BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,641,531
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/11/2026- NAV
- NAV Change
- Market Price $82.27
- Market Price Change $+4.21
- Trading Volume (M) 9,380
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,641,531
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/11/2026- NAV
- NAV Change
- Market Price $82.27
- Market Price Change $+4.21
- Trading Volume (M) 9,380
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/11/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.84% | AMGN | AMGEN INC | -- | $3,470,850.18 | 9,803 | 2023607 |
| 4.76% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,407,671.28 | 7,657 | 2931034 |
| 4.49% | GILD | GILEAD SCIENCES INC | -- | $3,214,971.54 | 25,542 | 2369174 |
| 3.28% | REGN | REGENERON PHARMACEUTICALS | -- | $2,348,083.20 | 3,840 | 2730190 |
| 1.98% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,419,168.56 | 4,904 | B00FWN1 |
| 1.53% | RVMD | REVOLUTION MEDICINES INC | -- | $1,093,258.98 | 7,326 | BL71K91 |
| 1.51% | BIIB | BIOGEN INC | -- | $1,084,783.00 | 5,425 | 2455965 |
| 1.32% | ARGX | ARGENX SE - ADR | -- | $943,887.00 | 1,050 | BDVLM39 |
| 1.31% | ILMN | ILLUMINA INC | -- | $939,585.13 | 5,653 | 2613990 |
| 1.23% | UTHR | UNITED THERAPEUTICS CORP | -- | $883,548.00 | 1,620 | 2430412 |
| 1.22% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $875,627.73 | 15,837 | BMVP7Y0 |
| 1.11% | INCY | INCYTE CORP | -- | $793,520.97 | 7,359 | 2471950 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $786,655.80 | 26,460 | BMW4NZ9 |
| 1.08% | INSM | INSMED INC | -- | $770,664.96 | 7,968 | 2614487 |
| 1.01% | MRNA | MODERNA INC | -- | $724,744.00 | 14,600 | BGSXTS3 |
| 0.97% | VTRS | VIATRIS INC | -- | $694,235.15 | 42,565 | BMWS3X9 |
| 0.89% | GH | GUARDANT HEALTH INC | -- | $634,865.00 | 4,850 | BFXC911 |
| 0.84% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $603,979.52 | 3,712 | 2623911 |
| 0.75% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $537,286.75 | 2,275 | B4Q5ZN4 |
| 0.72% | EXEL | EXELIXIS INC | -- | $513,600.00 | 9,600 | 2576941 |
| 0.70% | MEDP | MEDPACE HOLDINGS INC | -- | $499,298.57 | 1,051 | BDCBC61 |
| 0.68% | ASND | ASCENDIS PHARMA A/S | -- | $490,705.60 | 2,276 | BWXJHM8 |
| 0.68% | BBIO | BRIDGEBIO PHARMA INC | -- | $484,130.85 | 7,167 | BK1KWG8 |
| 0.67% | AXSM | AXSOME THERAPEUTICS INC | -- | $479,625.30 | 1,890 | BYZR4X4 |
| 0.63% | IONS | IONIS PHARMACEUTICALS INC | -- | $450,966.38 | 6,109 | BDJ0LS6 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $401,715.16 | 847 | BD59BS7 |
| 0.56% | SNY | SANOFI-ADR | -- | $399,063.17 | 9,047 | 2964557 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $394,889.40 | 7,110 | 2437071 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $385,294.98 | 5,178 | BYQBFJ8 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $377,232.02 | 4,213 | BK6H543 |
| 0.52% | SMMT | SUMMIT THERAPEUTICS INC | -- | $374,925.12 | 28,664 | BMTVQS7 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $347,268.60 | 1,080 | BD6JX35 |
| 0.47% | NUVL | NUVALENT INC-A | -- | $333,932.25 | 2,705 | BMVBZD3 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $318,566.16 | 6,424 | BSLSJJ0 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $315,386.31 | 4,553 | BBBSBJ5 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $308,665.72 | 4,364 | 2975098 |
| 0.43% | ONC | BEONE MEDICINES LTD-ADR | -- | $307,378.87 | 1,181 | BYYWPW6 |
| 0.39% | ALKS | ALKERMES PLC | -- | $276,841.96 | 6,163 | B3P6D26 |
| 0.38% | IBRX | IMMUNITYBIO INC | -- | $273,657.60 | 38,008 | BNSP0B8 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $259,214.19 | 2,361 | BDCBCD8 |
| 0.36% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $255,171.42 | 1,029 | BQ721R4 |
| 0.35% | PCVX | VAXCYTE INC | -- | $251,630.09 | 5,321 | BKPVGH6 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $250,290.32 | 3,017 | BMPRZV5 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $247,356.24 | 7,523 | BJRFSB7 |
| 0.33% | SYRE | SPYRE THERAPEUTICS INC | -- | $234,636.85 | 2,905 | BQBBDY8 |
| 0.32% | ABVX | ABIVAX SA-ADR | -- | $229,075.77 | 2,271 | BLC89B2 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $228,762.02 | 3,062 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $222,073.74 | 2,231 | BJDX8Y8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $221,429.16 | 2,526 | BF2YWG4 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $195,785.24 | 6,002 | BLR6XK8 |
| 0.27% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $190,066.88 | 11,632 | BFNF1D6 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $187,758.00 | 10,431 | BT18HP9 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $187,363.52 | 736 | 2501578 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $181,506.00 | 2,028 | BM9HHL5 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $180,009.72 | 3,123 | BRBCSP4 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $178,316.50 | 3,550 | BDHF4K6 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $176,313.12 | 4,624 | BTZRLN8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,902.71 | 4,423 | BLB0YQ9 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $168,615.37 | 3,773 | BFZQ0L8 |
| 0.23% | TWST | TWIST BIOSCIENCE CORP | -- | $167,797.30 | 2,266 | BGKG6G7 |
| 0.23% | TVTX | TRAVERE THERAPEUTICS INC | -- | $166,734.19 | 3,409 | BLFGJD5 |
| 0.22% | XENE | XENON PHARMACEUTICALS INC | -- | $160,432.06 | 3,074 | BRJ3GY4 |
| 0.22% | ERAS | ERASCA INC | -- | $160,330.44 | 11,444 | BNLYBF3 |
| 0.21% | TNGX | TANGO THERAPEUTICS INC | -- | $148,443.96 | 4,978 | BP2P6L0 |
| 0.19% | VCYT | VERACYTE INC | -- | $139,319.96 | 2,938 | BFTWZY0 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $134,821.17 | 6,303 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $134,566.38 | 3,966 | BKY5JZ8 |
| 0.18% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $129,828.16 | 3,872 | BDD19F8 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $128,665.52 | 4,252 | BP8JSP4 |
| 0.18% | TXG | 10X GENOMICS INC-CLASS A | -- | $126,396.55 | 4,351 | BKS3RS7 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $124,704.00 | 2,880 | BQS9486 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $123,240.26 | 5,863 | BD2B4V0 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $122,492.83 | 1,789 | BKVF0J2 |
| 0.16% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $113,266.16 | 3,122 | BMX9K07 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $112,794.33 | 4,587 | BKX9VD3 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $110,787.47 | 3,767 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $109,261.65 | 6,087 | BN15WD1 |
| 0.15% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $106,611.16 | 5,692 | BJ5FZ74 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $98,485.53 | 1,573 | BMH5RL1 |
| 0.14% | ALMS | ALUMIS INC | -- | $97,686.60 | 4,674 | BPLQG36 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $96,566.00 | 2,120 | B72ZBG4 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $96,060.88 | 1,411 | BMGJZJ8 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $94,069.44 | 6,606 | BN2R582 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $93,614.64 | 3,246 | BK0VHF6 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $88,845.35 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $88,701.40 | 2,636 | BL55460 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $88,630.56 | 2,196 | BMFD115 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $87,582.84 | 1,698 | BRXB0C0 |
| 0.12% | GRAL | GRAIL INC | -- | $86,570.24 | 1,439 | BSLSSX7 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $85,632.58 | 3,571 | BJ62Z18 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $78,803.50 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $77,886.90 | 4,914 | BFWLC09 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $76,602.35 | 2,255 | BFXC933 |
| 0.11% | PHVS | PHARVARIS NV | -- | $76,217.40 | 2,367 | BMZ2X38 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $75,328.00 | 2,140 | BKSGZN7 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $74,541.39 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $73,257.60 | 8,805 | B9NSBM2 |
| 0.10% | VCEL | VERICEL CORP | -- | $72,318.75 | 1,875 | BSBMN89 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,026.30 | 8,049 | BNZB1X8 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $70,024.50 | 2,925 | BP9N0G0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,769.50 | 830 | BCDWBX6 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $64,557.96 | 3,802 | BMVLGP2 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $63,827.32 | 4,742 | BJH9ZN0 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $63,521.19 | 2,766 | BPCQZY9 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,207.52 | 2,166 | BCBVTX1 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $62,110.44 | 1,764 | BR3T9B6 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $61,978.96 | 2,111 | BJQ05Z6 |
| 0.09% | QURE | UNIQURE NV | -- | $61,820.10 | 2,305 | BJFSR88 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $61,760.50 | 1,658 | BQXJKH2 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,485.60 | 2,740 | BDDXF67 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,785.55 | 19,297 | BM9FJ13 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,318.72 | 15,232 | BF0DMK7 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $60,045.96 | 2,379 | BBC9WC7 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $59,518.55 | 1,651 | BQKXDX4 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,252.40 | 13,080 | BKM5C84 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,071.43 | 11,209 | BL53SR3 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $58,404.51 | 3,261 | BN7Q7R7 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $58,285.85 | 3,455 | BRXYZ57 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $58,125.00 | 3,875 | B8DPDT7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,514.24 | 10,128 | BNC1BX1 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $56,460.69 | 4,059 | BPCK358 |
| 0.08% | SEPN | SEPTERNA INC | -- | $56,387.71 | 1,657 | BQNKXX2 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $55,487.52 | 1,023 | BDRW1L7 |
| 0.08% | NVAX | NOVAVAX INC | -- | $54,387.69 | 6,023 | BJDQXG4 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $53,957.15 | 4,369 | BYZM6C2 |
| 0.07% | ARDX | ARDELYX INC | -- | $52,492.14 | 9,066 | BN89V40 |
| 0.07% | HROW | HARROW INC | -- | $51,580.50 | 1,370 | BHNDW86 |
| 0.07% | ALVO | ALVOTECH SA | -- | $51,526.20 | 12,210 | BPNTJ34 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $51,035.00 | 1,730 | BZ7PJQ1 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $51,030.20 | 13,429 | BWJDYK1 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $50,475.18 | 1,974 | BMVNDH9 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,230.98 | 537 | BNSP8K3 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $49,859.04 | 2,343 | BQB42F1 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $49,501.20 | 5,810 | BK4PZ38 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $48,187.80 | 2,818 | BP7KZP7 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $47,394.04 | 2,294 | BP6C0S2 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,393.02 | 1,621 | BLCD809 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,115.40 | 1,527 | BMGTLY5 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $42,832.02 | 1,778 | BSRK699 |
| 0.06% | MNKD | MANNKIND CORP | -- | $42,708.75 | 11,389 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,508.62 | 6,134 | BLR7H87 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $40,437.60 | 6,960 | BYZG9R0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,246.48 | 1,172 | BX7RSN3 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $39,786.67 | 3,487 | BMC3HS7 |
| 0.06% | SVRA | SAVARA INC | -- | $39,651.48 | 7,524 | BYXGN81 |
| 0.05% | EYPT | EYEPOINT INC | -- | $38,275.00 | 3,062 | BMGS7L1 |
| 0.05% | PSNL | PERSONALIS INC | -- | $36,445.98 | 3,869 | BJQ0608 |
| 0.05% | ABSI | ABSCI CORP | -- | $36,202.11 | 5,561 | BN94K69 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,426.40 | 3,054 | BYP80F1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $35,218.08 | 1,983 | BQB42H3 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,061.04 | 3,656 | BMCR7V2 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,923.20 | 1,495 | B3X26D8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $34,428.81 | 1,677 | BNFWZS4 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,779.90 | 4,510 | B8K7T65 |
| 0.05% | XNCR | XENCOR INC | -- | $32,775.99 | 2,711 | BGCYWN8 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,853.12 | 992 | BGL0JK3 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,918.75 | 1,875 | BMNDK09 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,748.66 | 2,251 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,501.90 | 7,110 | BZ0QMB7 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,906.24 | 2,912 | BJLKVS6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $29,020.02 | 3,711 | BKVDFF7 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $28,879.50 | 2,962 | BMZ4LN0 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,560.00 | 2,975 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,511.48 | 3,218 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $28,361.30 | 2,185 | BM90J52 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $28,186.10 | 5,410 | BMCWKZ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,836.55 | 8,837 | BBNBTD2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $27,308.08 | 1,934 | BQS7491 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $27,281.73 | 9,849 | BMFJJ97 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $27,016.51 | 2,083 | BLFBZ32 |
| 0.04% | GERN | GERON CORP | -- | $26,906.28 | 23,602 | 2370381 |
| 0.04% | OMER | OMEROS CORP | -- | $26,691.96 | 2,622 | B4NB858 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,385.80 | 1,604 | BT9K6D8 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $26,316.86 | 3,053 | BDDVW37 |
| 0.04% | CRMD | CORMEDIX INC | -- | $26,082.56 | 2,911 | BJ0LT31 |
| 0.04% | ANNX | ANNEXON INC | -- | $25,140.30 | 5,349 | BMVV9R5 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,851.38 | 763 | BL95N25 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,111.00 | 1,100 | BKLCWZ3 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $22,385.16 | 1,269 | BD9GVY0 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,165.65 | 2,105 | BMFK3H6 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,089.12 | 2,707 | BP0TQC5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $21,881.64 | 6,028 | B3MZ6K5 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $21,642.24 | 1,536 | BRJJYT3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,557.76 | 672 | BQD3J33 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,793.60 | 2,880 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,332.62 | 693 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,485.83 | 4,459 | BYV2W40 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,991.31 | 4,511 | BYVQJ96 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,817.86 | 6,673 | BPBJFM7 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,669.70 | 6,265 | BYWVTY5 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,421.69 | 1,023 | BS2CR64 |
| 0.02% | ARVN | ARVINAS INC | -- | $16,753.67 | 2,363 | BDZ30Q0 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,653.98 | 1,885 | BKLXFX5 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,621.44 | 2,112 | BSMLR16 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,559.00 | 571 | BS2F741 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,429.14 | 1,989 | B91XRN2 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,876.96 | 2,134 | B2Q9833 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,859.12 | 548 | B292NQ7 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,619.04 | 8,308 | BFZNYB7 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,604.47 | 2,397 | BDRJH21 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,070.05 | 11,163 | B4N8MH9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,587.29 | 2,349 | BP81R42 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,450.40 | 4,014 | BMXNGZ6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,966.83 | 3,609 | BKX9NQ0 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,585.17 | 1,879 | B7F2TY6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,334.60 | 2,186 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,330.64 | 1,124 | BPRBTY7 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,740.86 | 1,997 | BRCFFK6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,596.04 | 2,889 | BLN9Z50 |
| 0.02% | OABI | OMNIAB INC | -- | $12,453.48 | 5,322 | BN13S71 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,338.72 | 1,072 | B9L5200 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $11,994.29 | 4,631 | BFY7DC4 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,762.44 | 1,873 | BZ0G875 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,596.48 | 1,736 | BL5B6Z1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,565.84 | 7,414 | BFMLGR4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,404.26 | 2,646 | 2107437 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,327.40 | 2,697 | BQ6C357 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,306.25 | 1,125 | BM7V485 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,993.28 | 6,176 | BN4JN37 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,797.64 | 787 | BTNMG41 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $10,706.57 | 3,557 | BK5MWR1 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,674.58 | 4,013 | BDFKQ07 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,834.44 | 2,387 | BMVBZF5 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,934.96 | 1,416 | BP81RK8 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,810.84 | 3,611 | BZ8FPH3 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,789.90 | 2,165 | BMF7DT9 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,747.20 | 2,464 | BJDX8Z9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,716.40 | 1,981 | BP7L561 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,565.00 | 3,426 | BYTYP72 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,502.23 | 2,089 | BPRB2N7 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,409.46 | 3,721 | BZC0D70 |
| 0.01% | IVVD | INVIVYD INC | -- | $8,323.25 | 10,244 | BM8NHS1 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,051.81 | 3,341 | B5LL2C2 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,845.50 | 5,525 | BRK0149 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,836.55 | 1,387 | 2517058 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,706.88 | 7,136 | BMYTJP4 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,539.34 | 2,179 | BY7RB53 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,527.00 | 1,158 | BQV0J03 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,375.21 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,332.44 | 1,052 | BKC9SX3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,034.79 | 7,230 | BNR5QT9 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,015.10 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,101.97 | 4,151 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,767.04 | 8,012 | BNNXX52 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,733.64 | 3,454 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,676.82 | 2,743 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,846.01 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,836.91 | 2,541 | BMTX3D7 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,831.10 | 2,105 | BKTV702 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,926.56 | 804 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,893.62 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,517.66 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 33.97% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 24,333,615 | -- | 4,108 | -- |
| 29.14% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,874,308 | -- | 3,524 | -- |
| 25.43% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,214,670 | -- | 3,075 | -- |
| 21.82% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,632,037 | -- | 2,639 | -- |
| 20.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,885,680 | -- | 2,513 | -- |
| 5.23% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,749,557 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $20,772,773.34 | 20,772,773 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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