BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View fund details
Documents & Downloads
ETF & Index
Prospectus & Regulatory
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/17/2026- NAV $80.32
- NAV Change $+0.08
- Market Price $80.23
- Market Price Change $+0.03
- Trading Volume (M) 6,528
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/17/2026- NAV $80.32
- NAV Change $+0.08
- Market Price $80.23
- Market Price Change $+0.03
- Trading Volume (M) 6,528
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/17/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.81% | GILD | GILEAD SCIENCES INC | -- | $5,522,578.00 | 38,245 | 2369174 |
| 6.33% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,132,714.02 | 11,098 | 2931034 |
| 6.20% | AMGN | AMGEN INC | -- | $5,031,624.29 | 13,933 | 2023607 |
| 4.28% | REGN | REGENERON PHARMACEUTICALS | -- | $3,469,617.55 | 4,571 | 2730190 |
| 2.31% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,873,175.32 | 5,846 | B00FWN1 |
| 1.67% | INSM | INSMED INC | -- | $1,358,267.41 | 9,437 | 2614487 |
| 1.48% | BIIB | BIOGEN INC | -- | $1,202,902.68 | 6,492 | 2455965 |
| 1.27% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,028,198.08 | 1,904 | 2430412 |
| 1.15% | MRNA | MODERNA INC | -- | $932,395.77 | 17,289 | BGSXTS3 |
| 1.12% | ARGX | ARGENX SE - ADR | -- | $908,660.61 | 1,287 | BDVLM39 |
| 1.07% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $871,940.10 | 18,910 | BMVP7Y0 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $871,045.70 | 30,779 | BMW4NZ9 |
| 1.05% | RVMD | REVOLUTION MEDICINES INC | -- | $848,057.15 | 8,555 | BL71K91 |
| 1.01% | INCY | INCYTE CORP | -- | $818,489.14 | 8,687 | 2471950 |
| 1.01% | ILMN | ILLUMINA INC | -- | $816,999.24 | 6,761 | 2613990 |
| 0.87% | VTRS | VIATRIS INC | -- | $703,413.60 | 50,972 | BMWS3X9 |
| 0.76% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $619,867.08 | 2,718 | BV9G6B8 |
| 0.75% | BBIO | BRIDGEBIO PHARMA INC | -- | $604,976.32 | 8,528 | BK1KWG8 |
| 0.71% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $576,692.52 | 4,412 | 2623911 |
| 0.70% | MEDP | MEDPACE HOLDINGS INC | -- | $567,572.05 | 1,247 | BDCBC61 |
| 0.64% | SMMT | SUMMIT THERAPEUTICS INC | -- | $522,209.95 | 32,947 | BMTVQS7 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $518,389.11 | 7,167 | BDJ0LS6 |
| 0.64% | SNY | SANOFI-ADR | -- | $516,030.72 | 11,712 | 2964557 |
| 0.63% | GH | GUARDANT HEALTH INC | -- | $508,093.75 | 5,725 | BFXC911 |
| 0.61% | EXEL | EXELIXIS INC | -- | $496,312.95 | 11,865 | 2576941 |
| 0.60% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $487,703.93 | 2,689 | B4Q5ZN4 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $476,537.10 | 8,502 | 2437071 |
| 0.55% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $444,509.54 | 1,003 | BD59BS7 |
| 0.52% | BNTX | BIONTECH SE-ADR | -- | $424,403.64 | 4,474 | BK6H543 |
| 0.49% | ONC | BEONE MEDICINES LTD-ADR | -- | $400,538.02 | 1,394 | BYYWPW6 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $388,875.16 | 7,649 | BSLSJJ0 |
| 0.44% | AXSM | AXSOME THERAPEUTICS INC | -- | $359,570.27 | 2,231 | BYZR4X4 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $357,882.11 | 43,591 | BNSP0B8 |
| 0.43% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $345,995.70 | 6,010 | BYQBFJ8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $339,001.65 | 5,205 | 2975098 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $336,247.56 | 5,412 | BBBSBJ5 |
| 0.41% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $335,841.66 | 1,107 | BQ721R4 |
| 0.41% | ABVX | ABIVAX SA-ADR | -- | $330,731.44 | 2,612 | BLC89B2 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $328,615.06 | 1,282 | BD6JX35 |
| 0.40% | PCVX | VAXCYTE INC | -- | $321,340.16 | 5,792 | BKPVGH6 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $316,407.09 | 3,197 | BMVBZD3 |
| 0.36% | ACLX | ARCELLX INC | -- | $293,056.68 | 2,559 | BPCJ1Q2 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $269,035.41 | 2,767 | BDCBCD8 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $258,919.04 | 2,953 | BF2YWG4 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $258,572.64 | 3,184 | BMPRZV5 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $244,976.16 | 3,569 | BRBCSP4 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $240,643.48 | 6,794 | BLR6XK8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $239,717.30 | 3,554 | B17VCN9 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $231,490.44 | 12,486 | BT18HP9 |
| 0.27% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $219,554.70 | 2,274 | BJDX8Y8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $211,229.53 | 4,217 | BDHF4K6 |
| 0.25% | ALKS | ALKERMES PLC | -- | $202,010.90 | 7,306 | B3P6D26 |
| 0.24% | FOLD | AMICUS THERAPEUTICS INC | -- | $196,236.72 | 13,656 | B19FQ48 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $194,725.80 | 7,758 | BJRFSB7 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $188,839.20 | 3,421 | BRJ3GY4 |
| 0.23% | TERN | TERNS PHARMACEUTICALS INC | -- | $185,229.42 | 3,986 | BMDJ0C9 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $183,805.65 | 4,515 | BFZQ0L8 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $183,561.30 | 870 | 2501578 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,035.59 | 5,523 | BTZRLN8 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $172,938.59 | 13,913 | BFNF1D6 |
| 0.21% | ADMA | ADMA BIOLOGICS INC | -- | $170,124.10 | 10,534 | B9NSBM2 |
| 0.21% | APGE | APOGEE THERAPEUTICS INC | -- | $169,525.95 | 2,427 | BM9HHL5 |
| 0.21% | ERAS | ERASCA INC | -- | $167,734.80 | 12,555 | BNLYBF3 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $166,035.55 | 2,957 | BQS9486 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $159,100.11 | 4,199 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $156,499.20 | 7,488 | 2713317 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $153,520.20 | 5,017 | BP8JSP4 |
| 0.19% | SYRE | SPYRE THERAPEUTICS INC | -- | $150,880.35 | 3,433 | BQBBDY8 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $142,892.50 | 4,685 | BKY5JZ8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $134,407.90 | 6,490 | BD2B4V0 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $132,967.60 | 3,880 | BK0VHF6 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $131,205.20 | 1,880 | BMH5RL1 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $128,930.34 | 2,537 | B72ZBG4 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $127,939.68 | 2,706 | BGKG6G7 |
| 0.15% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $123,587.55 | 4,269 | BLB0YQ9 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $123,187.84 | 5,422 | BKX9VD3 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $117,968.52 | 6,322 | BN15WD1 |
| 0.14% | VCYT | VERACYTE INC | -- | $117,079.56 | 3,497 | BFTWZY0 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $115,976.70 | 4,490 | BK6L288 |
| 0.14% | ALMS | ALUMIS INC | -- | $112,781.63 | 4,303 | BPLQG36 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $111,351.48 | 5,961 | BP2P6L0 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $111,157.64 | 2,827 | BL55460 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $109,929.60 | 3,960 | BLFGJD5 |
| 0.13% | MAZE | MAZE THERAPEUTICS INC | -- | $107,280.31 | 2,129 | BSRK699 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $105,316.72 | 5,596 | BYTQ6X1 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $100,286.56 | 1,672 | BMGJZJ8 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $96,720.47 | 4,543 | BLB0YH0 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $93,992.98 | 1,999 | BRXB0C0 |
| 0.11% | TXG | 10X GENOMICS INC-CLASS A | -- | $93,235.86 | 5,154 | BKS3RS7 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $92,228.92 | 7,402 | BYZG9R0 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $92,210.40 | 4,269 | BJ62Z18 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $91,419.42 | 3,846 | BN7Q7R7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $90,449.45 | 6,755 | BJ5FZ74 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $89,567.04 | 2,362 | BMVNDH9 |
| 0.11% | ORKA | ORUKA THERAPEUTICS INC | -- | $88,527.33 | 2,143 | BKVF0J2 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $87,595.02 | 3,501 | BP9N0G0 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $85,809.57 | 9,317 | 2100362 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $84,446.92 | 5,836 | BFWLC09 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $83,062.49 | 2,527 | BJQ05Z6 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $82,362.96 | 1,224 | BDRW1L7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,843.72 | 9,429 | BNZB1X8 |
| 0.10% | GRAL | GRAIL INC | -- | $81,713.25 | 1,725 | BSLSSX7 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $79,620.48 | 3,312 | BPCQZY9 |
| 0.10% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $78,854.31 | 4,359 | BV2DHY6 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $78,694.20 | 7,670 | BN2R582 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $78,087.08 | 4,637 | B8DPDT7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $77,825.52 | 22,756 | BM9FJ13 |
| 0.09% | NVAX | NOVAVAX INC | -- | $76,522.88 | 7,192 | BJDQXG4 |
| 0.09% | PHVS | PHARVARIS NV | -- | $76,318.20 | 2,835 | BMZ2X38 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,616.71 | 2,581 | BCBVTX1 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $73,908.60 | 995 | BCDWBX6 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $73,004.33 | 2,627 | BMFD115 |
| 0.09% | INVA | INNOVIVA INC | -- | $72,996.54 | 3,309 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,767.50 | 2,239 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,315.13 | 2,549 | BKSGZN7 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $70,748.16 | 1,974 | BQKXDX4 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $69,463.69 | 4,861 | BPCK358 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,427.80 | 4,485 | BMVLGP2 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $69,117.30 | 3,726 | BMX9K07 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,098.48 | 5,126 | BYZM6C2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $68,339.52 | 17,568 | BF0DMK7 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $68,219.68 | 2,588 | BBC9WC7 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $63,503.25 | 5,675 | BJH9ZN0 |
| 0.08% | ARDX | ARDELYX INC | -- | $62,684.16 | 10,752 | BN89V40 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $61,194.25 | 4,955 | BYSS4X4 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,339.63 | 1,931 | BLCD809 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $59,063.64 | 1,986 | BQXJKH2 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $58,670.10 | 16,074 | BWJDYK1 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $58,454.84 | 2,108 | BR3T9B6 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $58,368.36 | 6,157 | BK4PZ38 |
| 0.07% | HROW | HARROW INC | -- | $57,706.74 | 1,638 | BHNDW86 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $55,999.80 | 2,348 | BFXC933 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $55,788.48 | 2,376 | BQB42H3 |
| 0.07% | PGEN | PRECIGEN INC | -- | $55,436.40 | 15,660 | BKM5C84 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,402.11 | 12,123 | BNC1BX1 |
| 0.07% | ALVO | ALVOTECH SA | -- | $52,922.28 | 13,854 | BPNTJ34 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $52,421.51 | 3,482 | BMZ4LN0 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $52,033.77 | 4,311 | BKVDFF7 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,062.25 | 3,305 | BYP80F1 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,915.70 | 3,663 | BMGS7L1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $50,008.00 | 1,400 | BX7RSN3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,836.60 | 1,980 | BQNKXX2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $47,626.57 | 907 | BL95N25 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,023.30 | 13,246 | BL53SR3 |
| 0.06% | BCAX | BICARA THERAPEUTICS INC | -- | $46,851.00 | 2,425 | BQB42F1 |
| 0.06% | SVRA | SAVARA INC | -- | $46,375.75 | 9,005 | BYXGN81 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $46,182.43 | 2,881 | BP7KZP7 |
| 0.06% | GERN | GERON CORP | -- | $45,763.38 | 28,249 | 2370381 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $44,962.95 | 645 | BNSP8K3 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $43,890.28 | 1,828 | BMGTLY5 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $43,299.98 | 5,399 | B8K7T65 |
| 0.05% | QURE | UNIQURE NV | -- | $43,064.34 | 2,757 | BJFSR88 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $42,147.84 | 2,744 | BP6C0S2 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,729.88 | 1,902 | B3X26D8 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,199.84 | 7,344 | BLR7H87 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $40,869.55 | 7,499 | BYWVTY5 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,702.85 | 2,035 | BNFWZS4 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,663.30 | 4,089 | BRXYZ57 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $38,893.75 | 4,375 | BMCR7V2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $38,518.48 | 2,072 | BZ7PJQ1 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,963.80 | 11,790 | BMFJJ97 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $37,415.15 | 2,663 | BMFX8Y7 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,112.32 | 8,512 | BZ0QMB7 |
| 0.05% | XNCR | XENCOR INC | -- | $37,098.40 | 3,160 | BGCYWN8 |
| 0.05% | MNKD | MANNKIND CORP | -- | $37,097.97 | 13,589 | BF081J4 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $37,061.28 | 2,238 | BD06CS0 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,926.44 | 6,404 | BMVV9R5 |
| 0.04% | OMER | OMEROS CORP | -- | $35,376.53 | 3,139 | B4NB858 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,132.16 | 2,614 | BM90J52 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $34,144.95 | 3,147 | BJLKVS6 |
| 0.04% | ARVN | ARVINAS INC | -- | $34,132.42 | 2,842 | BDZ30Q0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,676.14 | 1,587 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,436.90 | 1,291 | BKLCWZ3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,033.00 | 3,850 | BYZD465 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,961.66 | 1,733 | BD9GVY0 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,544.63 | 2,171 | BQS7491 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,236.48 | 2,244 | BMNDK09 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,631.77 | 7,987 | BPBJFM7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $28,669.09 | 10,579 | BBNBTD2 |
| 0.03% | PSNL | PERSONALIS INC | -- | $27,981.60 | 3,930 | BJQ0608 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,842.88 | 2,522 | BMFK3H6 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,241.65 | 3,561 | BFYQFJ2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,756.48 | 3,448 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $26,065.44 | 828 | BPBPCG8 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $25,276.26 | 4,171 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,670.80 | 2,492 | BLFBZ32 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $24,304.00 | 3,472 | BDDVW37 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,400.00 | 7,200 | B3MZ6K5 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,206.90 | 2,390 | BRCFFK6 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,696.17 | 2,553 | B2Q9833 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,575.15 | 9,945 | BFZNYB7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $22,532.48 | 3,488 | BJ0LT31 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $22,489.00 | 2,615 | B12W3P6 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $22,476.96 | 1,188 | BGL0JK3 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,189.89 | 5,399 | BYVQJ96 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $22,145.29 | 4,783 | BDFKQ07 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,757.47 | 2,527 | BKLXFX5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $21,447.00 | 2,383 | B91XRN2 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,314.87 | 1,693 | BP81RK8 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $21,313.25 | 641 | B292NQ7 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $21,191.41 | 3,457 | BLN9Z50 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,156.76 | 802 | BQD3J33 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $20,925.02 | 7,394 | BN4JN37 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $20,601.02 | 3,229 | BQ6C357 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,167.68 | 6,656 | BN94K69 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,021.04 | 6,417 | BMCWKZ2 |
| 0.02% | IVVD | INVIVYD INC | -- | $19,501.35 | 12,265 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,362.24 | 2,241 | BZ0G875 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,129.29 | 2,809 | BP81R42 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,871.18 | 937 | BTNMG41 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $18,608.48 | 4,796 | BYV2W40 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,439.56 | 13,362 | B4N8MH9 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $17,990.70 | 3,954 | BYTYP72 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $17,787.42 | 2,394 | BJDX8Z9 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $17,312.50 | 1,385 | BQV0J03 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,063.20 | 1,939 | BSMLR16 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,959.06 | 1,278 | B9L5200 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $16,591.44 | 3,788 | BMXNGZ6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,301.54 | 4,618 | BFY7DC4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $15,908.38 | 3,169 | 2107437 |
| 0.02% | PEPG | PEPGEN INC | -- | $15,488.87 | 3,043 | BMTX3D7 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,297.66 | 1,349 | BM7V485 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,754.08 | 4,444 | BZC0D70 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,439.80 | 685 | BS2F741 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,365.89 | 2,079 | BL5B6Z1 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,091.70 | 2,870 | BDRJH21 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,718.40 | 2,858 | BMVBZF5 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,692.20 | 2,230 | B7F2TY6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,505.73 | 1,022 | BPRBTY7 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,405.78 | 8,878 | BFMLGR4 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $13,248.00 | 4,600 | BKRRKY7 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,202.90 | 4,259 | BK5MWR1 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,665.18 | 2,503 | BMF7DT9 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $12,563.10 | 2,430 | BP0TQC5 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,837.64 | 4,289 | BKX9NQ0 |
| 0.01% | OABI | OMNIAB INC | -- | $11,658.93 | 6,371 | BN13S71 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,520.39 | 2,499 | BPRB2N7 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,632.12 | 4,322 | BZ8FPH3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,373.22 | 2,046 | BKDQKM6 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,221.40 | 745 | BRJJYT3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,219.44 | 2,607 | BY7RB53 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,612.92 | 8,287 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,988.00 | 5,350 | BRK0149 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,147.92 | 4,136 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,050.88 | 8,655 | BNR5QT9 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,038.62 | 1,258 | BKC9SX3 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,228.88 | 1,658 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,120.68 | 1,372 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,822.72 | 2,369 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,316.47 | 7,367 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,055.20 | 3,364 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,875.59 | 3,997 | B5LL2C2 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,656.58 | 4,318 | BNNXX18 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,626.29 | 2,523 | BKTV702 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,132.79 | 963 | BTXQTX3 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,832.65 | 10,243 | BJ0CK86 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,463.10 | 2,755 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $22.94 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.87% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,854,044 | -- | 4,475 | -- |
| 30.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,744,776 | -- | 4,283 | -- |
| 26.37% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,388,083 | -- | 3,702 | -- |
| 18.80% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,246,664 | -- | 2,639 | -- |
| 17.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,351,161 | -- | 2,484 | -- |
| 4.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,657,120 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $24,520,044.48 | 24,520,044 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More