BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,218,135
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/14/2026- NAV
- NAV Change
- Market Price $84.77
- Market Price Change $-1.23
- Trading Volume (M) 2,950
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,218,135
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/14/2026- NAV
- NAV Change
- Market Price $84.77
- Market Price Change $-1.23
- Trading Volume (M) 2,950
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/14/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.80% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,702,820.61 | 8,221 | 2931034 |
| 4.69% | GILD | GILEAD SCIENCES INC | -- | $3,621,349.32 | 27,422 | 2369174 |
| 4.55% | AMGN | AMGEN INC | -- | $3,511,630.33 | 10,523 | 2023607 |
| 3.81% | REGN | REGENERON PHARMACEUTICALS | -- | $2,939,875.88 | 4,124 | 2730190 |
| 2.00% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,544,720.80 | 5,264 | B00FWN1 |
| 1.52% | RVMD | REVOLUTION MEDICINES INC | -- | $1,175,731.02 | 7,866 | BL71K91 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,114,730.25 | 5,825 | 2455965 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,001,874.60 | 1,740 | 2430412 |
| 1.28% | INSM | INSMED INC | -- | $989,244.72 | 8,556 | 2614487 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $925,718.38 | 1,126 | BDVLM39 |
| 1.17% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $904,070.83 | 17,005 | BMVP7Y0 |
| 1.13% | ILMN | ILLUMINA INC | -- | $869,323.56 | 6,069 | 2613990 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $838,036.00 | 28,408 | BMW4NZ9 |
| 1.02% | VTRS | VIATRIS INC | -- | $788,799.26 | 45,701 | BMWS3X9 |
| 1.02% | MRNA | MODERNA INC | -- | $784,270.28 | 15,676 | BGSXTS3 |
| 1.00% | INCY | INCYTE CORP | -- | $771,179.37 | 7,899 | 2471950 |
| 0.82% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $633,655.20 | 3,984 | 2623911 |
| 0.78% | ASND | ASCENDIS PHARMA A/S | -- | $599,977.56 | 2,444 | BWXJHM8 |
| 0.73% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $564,455.15 | 2,443 | B4Q5ZN4 |
| 0.72% | SMMT | SUMMIT THERAPEUTICS INC | -- | $558,276.64 | 30,776 | BMTVQS7 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $536,033.70 | 7,695 | BK1KWG8 |
| 0.68% | EXEL | EXELIXIS INC | -- | $526,738.80 | 10,308 | 2576941 |
| 0.67% | GH | GUARDANT HEALTH INC | -- | $513,623.96 | 5,206 | BFXC911 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $496,233.76 | 6,557 | BDJ0LS6 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $491,839.79 | 911 | BD59BS7 |
| 0.61% | MEDP | MEDPACE HOLDINGS INC | -- | $472,404.59 | 1,127 | BDCBC61 |
| 0.61% | AXSM | AXSOME THERAPEUTICS INC | -- | $471,508.10 | 2,030 | BYZR4X4 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $442,917.02 | 5,558 | BYQBFJ8 |
| 0.54% | SNY | SANOFI-ADR | -- | $416,287.75 | 9,715 | 2964557 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $416,254.75 | 4,525 | BK6H543 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $406,434.16 | 7,634 | 2437071 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $386,562.78 | 1,269 | BYYWPW6 |
| 0.50% | CYTK | CYTOKINETICS INC | -- | $384,470.96 | 4,889 | BBBSBJ5 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $381,799.60 | 1,105 | BQ721R4 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $366,908.00 | 1,160 | BD6JX35 |
| 0.43% | IBRX | IMMUNITYBIO INC | -- | $332,585.20 | 40,808 | BNSP0B8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $324,179.64 | 4,684 | 2975098 |
| 0.41% | TEM | TEMPUS AI INC-CL A | -- | $313,630.08 | 6,896 | BSLSJJ0 |
| 0.40% | PCVX | VAXCYTE INC | -- | $305,816.89 | 5,713 | BKPVGH6 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $303,311.05 | 2,905 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $295,119.00 | 2,439 | BLC89B2 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $273,864.50 | 3,241 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $267,358.15 | 2,533 | BDCBCD8 |
| 0.35% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $266,779.05 | 2,395 | BJDX8Y8 |
| 0.33% | ALKS | ALKERMES PLC | -- | $253,751.40 | 6,615 | B3P6D26 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $253,737.30 | 2,710 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $238,957.92 | 3,286 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $235,801.05 | 3,117 | BQBBDY8 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $233,967.84 | 8,079 | BJRFSB7 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $233,011.79 | 3,351 | BRBCSP4 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $220,251.98 | 6,442 | BLR6XK8 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $207,632.72 | 4,049 | BFZQ0L8 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $192,214.50 | 3,810 | BDHF4K6 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $187,981.20 | 4,747 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $187,788.12 | 4,964 | BTZRLN8 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $184,912.00 | 3,302 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $182,588.16 | 2,176 | BM9HHL5 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $173,432.16 | 792 | 2501578 |
| 0.22% | CAI | CARIS LIFE SCIENCES INC | -- | $170,784.75 | 11,199 | BT18HP9 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $168,320.32 | 4,564 | BP8JSP4 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $161,450.10 | 3,661 | BLFGJD5 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $159,216.36 | 4,156 | BDD19F8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $152,728.24 | 12,488 | BFNF1D6 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $149,483.03 | 6,767 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $144,814.58 | 4,258 | BKY5JZ8 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $132,955.02 | 5,346 | BP2P6L0 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $128,880.30 | 2,434 | BGKG6G7 |
| 0.17% | ERAS | ERASCA INC | -- | $127,426.56 | 12,288 | BNLYBF3 |
| 0.16% | ALMS | ALUMIS INC | -- | $123,593.34 | 5,018 | BPLQG36 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $123,185.28 | 3,092 | BQS9486 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $122,751.90 | 1,921 | BKVF0J2 |
| 0.16% | VCYT | VERACYTE INC | -- | $122,690.60 | 3,154 | BFTWZY0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $122,060.05 | 6,295 | BD2B4V0 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $119,459.80 | 6,535 | BN15WD1 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $119,389.79 | 4,043 | BK6L288 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $116,531.20 | 2,276 | B72ZBG4 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $112,033.92 | 2,832 | BL55460 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $110,089.02 | 1,689 | BMH5RL1 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $106,659.88 | 1,822 | BRXB0C0 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $106,189.11 | 4,923 | BKX9VD3 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $105,595.50 | 1,515 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $101,496.48 | 2,356 | BMFD115 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $100,536.24 | 3,486 | BK0VHF6 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $100,519.92 | 4,671 | BKS3RS7 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $98,943.00 | 3,835 | BJ62Z18 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $95,810.00 | 3,350 | BMX9K07 |
| 0.12% | GRAL | GRAIL INC | -- | $95,604.60 | 1,547 | BSLSSX7 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $95,269.35 | 9,955 | 2100362 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $93,770.10 | 2,423 | BFXC933 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $90,661.32 | 7,094 | BN2R582 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $85,655.07 | 3,141 | BP9N0G0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,481.95 | 3,957 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $83,603.52 | 5,278 | BFWLC09 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,089.50 | 8,641 | BNZB1X8 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $81,531.85 | 4,517 | BYSS4X4 |
| 0.10% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $80,556.16 | 6,112 | BJ5FZ74 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $80,350.50 | 9,453 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,070.10 | 2,543 | BMZ2X38 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $77,690.12 | 4,159 | B8DPDT7 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $77,328.18 | 2,118 | BMVNDH9 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $76,757.20 | 5,090 | BJH9ZN0 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $75,745.67 | 1,771 | BQKXDX4 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $71,945.55 | 3,501 | BN7Q7R7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,801.40 | 1,892 | BR3T9B6 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $71,161.20 | 2,970 | BPCQZY9 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $71,093.12 | 2,267 | BJQ05Z6 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $70,826.20 | 890 | BCDWBX6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $70,624.96 | 2,296 | BKSGZN7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $68,729.50 | 2,555 | BBC9WC7 |
| 0.09% | QURE | UNIQURE NV | -- | $68,625.75 | 2,473 | BJFSR88 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $68,493.60 | 10,872 | BNC1BX1 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $68,346.81 | 1,099 | BDRW1L7 |
| 0.09% | INVA | INNOVIVA INC | -- | $67,208.40 | 2,940 | BDDXF67 |
| 0.09% | INBX | INHIBRX BIOSCIENCES INC | -- | $67,024.32 | 577 | BNSP8K3 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $66,825.98 | 2,326 | BCBVTX1 |
| 0.09% | VCEL | VERICEL CORP | -- | $66,777.10 | 2,015 | BSBMN89 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $65,312.00 | 4,082 | BMVLGP2 |
| 0.08% | PGEN | PRECIGEN INC | -- | $64,602.40 | 14,044 | BKM5C84 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $63,011.52 | 1,782 | BQXJKH2 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $62,979.68 | 20,717 | BM9FJ13 |
| 0.08% | ARDX | ARDELYX INC | -- | $62,881.64 | 9,734 | BN89V40 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $61,379.01 | 4,689 | BYZM6C2 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $60,502.92 | 4,359 | BPCK358 |
| 0.08% | NVAX | NOVAVAX INC | -- | $60,466.45 | 6,467 | BJDQXG4 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $58,244.68 | 14,417 | BWJDYK1 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,559.04 | 16,352 | BF0DMK7 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $56,703.42 | 6,238 | BK4PZ38 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $56,525.68 | 3,026 | BP7KZP7 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $55,145.44 | 1,858 | BZ7PJQ1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $54,681.02 | 2,462 | BP6C0S2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $53,680.56 | 2,006 | BD06CS0 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $52,945.20 | 12,033 | BL53SR3 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $52,844.64 | 3,711 | BRXYZ57 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $51,934.75 | 2,515 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $51,556.80 | 7,472 | BYZG9R0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,481.30 | 1,910 | BSRK699 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,324.64 | 1,777 | BQNKXX2 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $50,071.16 | 1,741 | BLCD809 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,580.38 | 1,639 | BMGTLY5 |
| 0.06% | HROW | HARROW INC | -- | $45,364.20 | 1,470 | BHNDW86 |
| 0.06% | ALVO | ALVOTECH SA | -- | $44,967.30 | 13,110 | BPNTJ34 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $44,761.09 | 3,278 | BYP80F1 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $43,975.24 | 3,182 | BMZ4LN0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $43,885.80 | 1,260 | BX7RSN3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $43,506.64 | 3,286 | BMGS7L1 |
| 0.06% | SVRA | SAVARA INC | -- | $42,560.52 | 8,076 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,018.68 | 6,586 | BLR7H87 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,820.40 | 3,128 | BJLKVS6 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $40,275.90 | 2,131 | BQB42H3 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $39,750.66 | 3,743 | BMC3HS7 |
| 0.05% | MNKD | MANNKIND CORP | -- | $39,377.38 | 12,229 | BF081J4 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,871.75 | 2,345 | BM90J52 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $37,812.71 | 1,607 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $37,719.18 | 4,842 | B8K7T65 |
| 0.05% | OMER | OMEROS CORP | -- | $37,369.92 | 2,814 | B4NB858 |
| 0.05% | GERN | GERON CORP | -- | $35,473.20 | 25,338 | 2370381 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $34,751.85 | 2,415 | BMFX8Y7 |
| 0.04% | XNCR | XENCOR INC | -- | $34,582.68 | 2,911 | BGCYWN8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,641.96 | 3,454 | BYZD465 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $33,218.22 | 3,983 | BKVDFF7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,207.90 | 7,634 | BZ0QMB7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $33,201.61 | 2,011 | BMNDK09 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $33,199.22 | 10,573 | BMFJJ97 |
| 0.04% | ABSI | ABSCI CORP | -- | $33,068.26 | 5,969 | BN94K69 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $32,874.94 | 2,261 | BMFK3H6 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,264.66 | 1,724 | BT9K6D8 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,877.44 | 1,064 | BGL0JK3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,790.25 | 3,195 | BFYQFJ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,336.24 | 2,078 | BQS7491 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $31,157.30 | 1,801 | BNFWZS4 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,156.56 | 3,924 | BMCR7V2 |
| 0.04% | ANNX | ANNEXON INC | -- | $30,850.65 | 5,745 | BMVV9R5 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $29,606.85 | 819 | BL95N25 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,605.68 | 9,489 | BBNBTD2 |
| 0.04% | PSNL | PERSONALIS INC | -- | $27,866.63 | 4,153 | BJQ0608 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $27,669.13 | 1,361 | BD9GVY0 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,060.10 | 2,235 | BLFBZ32 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,901.37 | 2,907 | BP0TQC5 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $25,420.50 | 6,725 | BYWVTY5 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,924.90 | 5,810 | BMCWKZ2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,835.36 | 1,648 | BRJJYT3 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,797.11 | 3,127 | BJ0LT31 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $24,358.32 | 2,268 | BSMLR16 |
| 0.03% | ARVN | ARVINAS INC | -- | $23,917.38 | 2,539 | BDZ30Q0 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,752.24 | 6,472 | B3MZ6K5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,591.96 | 3,092 | BQHN6C7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,982.40 | 720 | BQD3J33 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,977.60 | 4,787 | BYV2W40 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,907.39 | 4,843 | BYVQJ96 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $22,426.45 | 7,165 | BPBJFM7 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,278.40 | 1,180 | BKLCWZ3 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,201.00 | 745 | BPBPCG8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $21,070.82 | 2,137 | B91XRN2 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $20,117.58 | 2,521 | BP81R42 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $19,957.84 | 1,099 | BS2CR64 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,865.25 | 2,025 | BKLXFX5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $19,231.05 | 615 | BS2F741 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $19,088.80 | 8,920 | BFZNYB7 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $18,854.55 | 2,145 | BRCFFK6 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,798.84 | 2,644 | BJDX8Z9 |
| 0.02% | KMDA | KAMADA LTD | -- | $18,377.25 | 2,290 | B2Q9833 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,165.68 | 1,208 | BPRBTY7 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,930.34 | 2,573 | BDRJH21 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $16,765.90 | 4,310 | BMXNGZ6 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $16,164.12 | 588 | B292NQ7 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $16,155.61 | 3,277 | BDDVW37 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $16,033.86 | 843 | BTNMG41 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $15,933.50 | 2,897 | BQ6C357 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,909.12 | 1,152 | B9L5200 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,990.94 | 2,346 | B12W3P6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $14,650.60 | 4,309 | BDFKQ07 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,516.61 | 2,019 | B7F2TY6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,515.32 | 4,971 | BFY7DC4 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,504.27 | 11,987 | B4N8MH9 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $14,058.99 | 3,873 | BKX9NQ0 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,793.81 | 3,821 | BK5MWR1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,290.32 | 1,864 | BL5B6Z1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $13,286.91 | 1,209 | BM7V485 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $13,241.27 | 3,101 | BLN9Z50 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,173.82 | 2,563 | BMVBZF5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $13,065.04 | 6,632 | BN4JN37 |
| 0.02% | IVVD | INVIVYD INC | -- | $12,760.00 | 11,000 | BM8NHS1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,659.58 | 7,962 | BFMLGR4 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,546.21 | 2,009 | BZ0G875 |
| 0.02% | OABI | OMNIAB INC | -- | $12,513.66 | 5,714 | BN13S71 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,106.92 | 2,842 | 2107437 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,328.24 | 3,678 | BYTYP72 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $11,180.40 | 3,993 | BZC0D70 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,043.75 | 3,875 | BZ8FPH3 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,381.60 | 1,520 | BP81RK8 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,917.36 | 2,339 | BY7RB53 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,670.79 | 5,933 | BRK0149 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,393.00 | 2,325 | BMF7DT9 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,213.45 | 3,585 | B5LL2C2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,210.51 | 2,241 | BPRB2N7 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,072.47 | 1,231 | BP2NYN2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $9,054.18 | 1,242 | BQV0J03 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,832.24 | 1,128 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,588.13 | 1,839 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $8,553.60 | 4,455 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $8,044.74 | 8,604 | BNNXX52 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,939.40 | 3,710 | BNYJR68 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,905.00 | 2,125 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,660.00 | 7,660 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,241.17 | 7,762 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,765.85 | 1,487 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,466.46 | 2,261 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,129.76 | 2,947 | BPTK6Z2 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,814.72 | 864 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,460.91 | 2,471 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,502.85 | 2,729 | BMTX3D7 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,297.92 | 3,872 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,031.71 | 9,187 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 37.44% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,910,209 | -- | 4,828 | -- |
| 27.33% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,101,818 | -- | 3,524 | -- |
| 26.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,203,613 | -- | 3,374 | -- |
| 20.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,802,411 | -- | 2,639 | -- |
| 19.49% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 15,047,919 | -- | 2,513 | -- |
| 4.91% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,790,423 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $22,410,172.89 | 22,410,173 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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