BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,464,965
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/11/2026- NAV
- NAV Change
- Market Price $83.19
- Market Price Change $+0.29
- Trading Volume (M) 17,648
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,464,965
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/11/2026- NAV
- NAV Change
- Market Price $83.19
- Market Price Change $+0.29
- Trading Volume (M) 17,648
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/11/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.79% | GILD | GILEAD SCIENCES INC | -- | $3,632,144.56 | 27,203 | 2369174 |
| 4.68% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,547,941.01 | 8,153 | 2931034 |
| 4.54% | AMGN | AMGEN INC | -- | $3,440,590.01 | 10,439 | 2023607 |
| 3.85% | REGN | REGENERON PHARMACEUTICALS | -- | $2,914,516.53 | 4,089 | 2730190 |
| 1.96% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,486,864.80 | 5,220 | B00FWN1 |
| 1.51% | BIIB | BIOGEN INC | -- | $1,143,161.25 | 5,775 | 2455965 |
| 1.48% | RVMD | REVOLUTION MEDICINES INC | -- | $1,124,514.15 | 7,801 | BL71K91 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $983,043.00 | 1,725 | 2430412 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $908,433.76 | 1,117 | BDVLM39 |
| 1.16% | INSM | INSMED INC | -- | $881,714.43 | 8,487 | 2614487 |
| 1.15% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $871,128.90 | 16,866 | BMVP7Y0 |
| 1.13% | ILMN | ILLUMINA INC | -- | $857,910.20 | 6,020 | 2613990 |
| 1.08% | MRNA | MODERNA INC | -- | $822,125.36 | 15,547 | BGSXTS3 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $816,150.72 | 28,182 | BMW4NZ9 |
| 1.04% | INCY | INCYTE CORP | -- | $786,308.16 | 7,838 | 2471950 |
| 1.01% | VTRS | VIATRIS INC | -- | $767,034.36 | 45,333 | BMWS3X9 |
| 0.79% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $595,131.68 | 3,952 | 2623911 |
| 0.76% | ASND | ASCENDIS PHARMA A/S | -- | $578,297.41 | 2,423 | BWXJHM8 |
| 0.75% | SMMT | SUMMIT THERAPEUTICS INC | -- | $569,652.48 | 30,528 | BMTVQS7 |
| 0.71% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $541,807.03 | 2,423 | B4Q5ZN4 |
| 0.67% | EXEL | EXELIXIS INC | -- | $508,284.75 | 10,225 | 2576941 |
| 0.66% | GH | GUARDANT HEALTH INC | -- | $499,313.73 | 5,163 | BFXC911 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $493,702.44 | 7,633 | BK1KWG8 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $490,346.90 | 6,505 | BDJ0LS6 |
| 0.61% | MEDP | MEDPACE HOLDINGS INC | -- | $466,112.93 | 1,117 | BDCBC61 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $449,315.12 | 904 | BD59BS7 |
| 0.58% | AXSM | AXSOME THERAPEUTICS INC | -- | $435,970.58 | 2,014 | BYZR4X4 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $428,813.84 | 5,516 | BYQBFJ8 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $418,629.90 | 4,485 | BK6H543 |
| 0.54% | SNY | SANOFI-ADR | -- | $409,445.00 | 9,634 | 2964557 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $398,135.76 | 7,572 | 2437071 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $391,234.25 | 1,259 | BYYWPW6 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $363,663.76 | 1,096 | BQ721R4 |
| 0.48% | CYTK | CYTOKINETICS INC | -- | $361,616.00 | 4,850 | BBBSBJ5 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $361,063.52 | 1,154 | BD6JX35 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $331,369.48 | 6,838 | BSLSJJ0 |
| 0.43% | IBRX | IMMUNITYBIO INC | -- | $328,300.91 | 40,481 | BNSP0B8 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $308,673.68 | 4,648 | 2975098 |
| 0.40% | PCVX | VAXCYTE INC | -- | $305,853.35 | 5,665 | BKPVGH6 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $301,313.10 | 2,882 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $295,188.21 | 2,417 | BLC89B2 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $270,213.30 | 3,213 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $260,199.00 | 2,514 | BDCBCD8 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $252,259.92 | 2,376 | BJDX8Y8 |
| 0.33% | PTCT | PTC THERAPEUTICS INC | -- | $250,377.30 | 3,258 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $236,321.56 | 3,092 | BQBBDY8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $235,079.10 | 2,690 | BF2YWG4 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $232,974.02 | 8,017 | BJRFSB7 |
| 0.31% | ALKS | ALKERMES PLC | -- | $232,754.14 | 6,562 | B3P6D26 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $230,489.00 | 3,325 | BRBCSP4 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $217,967.20 | 6,392 | BLR6XK8 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $206,453.66 | 5,033 | BYTQ6X1 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,103.79 | 3,779 | BDHF4K6 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $194,270.30 | 4,018 | BFZQ0L8 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $191,170.48 | 4,922 | BTZRLN8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $186,429.31 | 4,709 | BLB0YQ9 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $182,735.28 | 3,276 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $182,651.40 | 2,159 | BM9HHL5 |
| 0.24% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $179,184.34 | 4,526 | BP8JSP4 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $177,093.40 | 11,110 | BT18HP9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $172,856.32 | 784 | 2501578 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $158,318.64 | 12,388 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $158,071.83 | 3,633 | BLFGJD5 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $150,659.10 | 4,122 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $146,299.80 | 6,711 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $145,981.44 | 4,224 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $135,690.94 | 2,414 | BGKG6G7 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $127,349.25 | 4,011 | BK6L288 |
| 0.17% | ERAS | ERASCA INC | -- | $127,274.04 | 12,191 | BNLYBF3 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $125,186.08 | 1,906 | BKVF0J2 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $124,490.96 | 5,302 | BP2P6L0 |
| 0.16% | VCYT | VERACYTE INC | -- | $124,300.70 | 3,131 | BFTWZY0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $122,819.48 | 6,244 | BD2B4V0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $119,657.72 | 6,482 | BN15WD1 |
| 0.16% | ALMS | ALUMIS INC | -- | $117,779.48 | 4,978 | BPLQG36 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $117,604.08 | 3,069 | BQS9486 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $111,477.46 | 2,258 | B72ZBG4 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $105,532.96 | 1,808 | BRXB0C0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $104,121.92 | 1,504 | BMGJZJ8 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $103,651.20 | 4,880 | BKX9VD3 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $102,874.10 | 2,810 | BL55460 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $100,071.50 | 3,805 | BJ62Z18 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $99,973.40 | 1,676 | BMH5RL1 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $97,301.67 | 3,459 | BK0VHF6 |
| 0.13% | KOD | KODIAK SCIENCES INC | -- | $95,719.70 | 2,402 | BFXC933 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $94,956.00 | 4,632 | BKS3RS7 |
| 0.12% | GRAL | GRAIL INC | -- | $93,850.32 | 1,532 | BSLSSX7 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $92,638.68 | 3,116 | BP9N0G0 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $92,601.01 | 2,339 | BMFD115 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $90,425.45 | 7,037 | BN2R582 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $85,002.34 | 3,323 | BMX9K07 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $84,736.08 | 9,876 | 2100362 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,016.40 | 3,926 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $82,309.92 | 5,236 | BFWLC09 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $82,093.02 | 6,063 | BJ5FZ74 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $81,088.00 | 4,480 | BYSS4X4 |
| 0.11% | SION | SIONNA THERAPEUTICS INC | -- | $80,780.10 | 1,758 | BQKXDX4 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $80,044.40 | 4,126 | B8DPDT7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $79,538.88 | 8,571 | BNZB1X8 |
| 0.10% | PHVS | PHARVARIS NV | -- | $75,533.90 | 2,522 | BMZ2X38 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $75,114.24 | 5,048 | BJH9ZN0 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $74,252.74 | 3,473 | BN7Q7R7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $74,236.56 | 1,093 | BDRW1L7 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $73,906.52 | 9,379 | B9NSBM2 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $73,546.88 | 10,784 | BNC1BX1 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $73,374.72 | 2,248 | BJQ05Z6 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $72,848.18 | 571 | BNSP8K3 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $72,133.11 | 1,877 | BR3T9B6 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $71,489.02 | 2,102 | BMVNDH9 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $70,840.44 | 2,948 | BPCQZY9 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $70,781.28 | 1,766 | BQXJKH2 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $69,500.93 | 883 | BCDWBX6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,780.22 | 2,279 | BKSGZN7 |
| 0.09% | QURE | UNIQURE NV | -- | $67,828.56 | 2,454 | BJFSR88 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $67,053.00 | 4,650 | BYZM6C2 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $66,999.52 | 20,552 | BM9FJ13 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $66,366.30 | 2,535 | BBC9WC7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $65,934.00 | 4,050 | BMVLGP2 |
| 0.09% | VCEL | VERICEL CORP | -- | $65,807.08 | 1,999 | BSBMN89 |
| 0.09% | INVA | INNOVIVA INC | -- | $65,668.32 | 2,916 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $64,544.94 | 2,306 | BCBVTX1 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $64,370.88 | 4,326 | BPCK358 |
| 0.08% | ARDX | ARDELYX INC | -- | $63,819.55 | 9,655 | BN89V40 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $62,664.00 | 11,936 | BL53SR3 |
| 0.08% | NVAX | NOVAVAX INC | -- | $60,923.50 | 6,413 | BJDQXG4 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $60,840.78 | 3,003 | BP7KZP7 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,014.00 | 16,220 | BF0DMK7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $58,522.80 | 13,934 | BKM5C84 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $57,767.96 | 14,299 | BWJDYK1 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $57,709.86 | 1,842 | BZ7PJQ1 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $57,467.94 | 6,186 | BK4PZ38 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $57,185.40 | 2,495 | BQB42F1 |
| 0.07% | HROW | HARROW INC | -- | $55,576.44 | 1,461 | BHNDW86 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $55,178.19 | 3,681 | BRXYZ57 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $53,152.90 | 1,990 | BD06CS0 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $52,409.91 | 7,413 | BYZG9R0 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $51,959.44 | 2,444 | BP6C0S2 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,414.12 | 3,252 | BYP80F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,795.10 | 1,726 | BLCD809 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $48,334.88 | 1,894 | BSRK699 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $47,244.56 | 1,628 | BMGTLY5 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $46,883.30 | 3,155 | BMZ4LN0 |
| 0.06% | ALVO | ALVOTECH SA | -- | $46,687.95 | 13,005 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $45,560.82 | 3,259 | BMGS7L1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,762.50 | 1,250 | BX7RSN3 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $43,798.80 | 2,147 | BQB42H3 |
| 0.05% | SEPN | SEPTERNA INC | -- | $41,506.77 | 1,761 | BQNKXX2 |
| 0.05% | SVRA | SAVARA INC | -- | $41,036.80 | 8,015 | BYXGN81 |
| 0.05% | MNKD | MANNKIND CORP | -- | $40,763.52 | 12,132 | BF081J4 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,118.76 | 6,534 | BLR7H87 |
| 0.05% | OMER | OMEROS CORP | -- | $40,064.40 | 2,790 | B4NB858 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,906.44 | 3,102 | BJLKVS6 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $37,447.80 | 4,801 | B8K7T65 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,340.84 | 10,489 | BMFJJ97 |
| 0.05% | XNCR | XENCOR INC | -- | $36,950.31 | 2,889 | BGCYWN8 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $36,179.34 | 1,591 | B3X26D8 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $35,840.10 | 3,714 | BMC3HS7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $35,528.48 | 3,952 | BKVDFF7 |
| 0.05% | DSGN | DESIGN THERAPEUTICS INC | -- | $34,982.01 | 2,241 | BMFK3H6 |
| 0.05% | GERN | GERON CORP | -- | $34,937.65 | 25,135 | 2370381 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,291.44 | 2,328 | BM90J52 |
| 0.05% | ABSI | ABSCI CORP | -- | $34,223.38 | 5,921 | BN94K69 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $34,109.31 | 2,397 | BMFX8Y7 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,479.80 | 3,893 | BMCR7V2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,241.08 | 7,572 | BZ0QMB7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $32,973.92 | 1,996 | BMNDK09 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $32,951.70 | 1,786 | BNFWZS4 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,581.26 | 3,426 | BYZD465 |
| 0.04% | ANNX | ANNEXON INC | -- | $32,370.32 | 5,699 | BMVV9R5 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,481.20 | 1,055 | BGL0JK3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,363.20 | 3,168 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,035.44 | 1,709 | BT9K6D8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $29,876.09 | 2,059 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,456.43 | 9,411 | BBNBTD2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $29,455.52 | 811 | BL95N25 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $28,238.25 | 1,637 | BRJJYT3 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,321.36 | 5,764 | BMCWKZ2 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,717.19 | 6,407 | B3MZ6K5 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $26,426.91 | 1,349 | BD9GVY0 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $25,746.20 | 6,670 | BYWVTY5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,470.30 | 2,878 | BP0TQC5 |
| 0.03% | ARVN | ARVINAS INC | -- | $24,323.88 | 2,518 | BDZ30Q0 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,932.80 | 2,216 | BLFBZ32 |
| 0.03% | PSNL | PERSONALIS INC | -- | $23,807.82 | 4,119 | BJQ0608 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,761.32 | 3,102 | BJ0LT31 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,577.60 | 3,070 | BQHN6C7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $23,497.65 | 4,747 | BYV2W40 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,254.66 | 2,249 | BSMLR16 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $23,026.68 | 7,107 | BPBJFM7 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,276.80 | 1,170 | BKLCWZ3 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,655.53 | 2,007 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,840.68 | 4,802 | BYVQJ96 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $20,504.68 | 1,093 | BS2CR64 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $20,475.00 | 2,500 | BP81R42 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,471.39 | 2,117 | B91XRN2 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,392.32 | 741 | BPBPCG8 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,178.00 | 8,850 | BFZNYB7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $20,089.44 | 1,993 | BZ0G875 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $19,376.97 | 2,127 | BRCFFK6 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,198.40 | 2,272 | B2Q9833 |
| 0.02% | NGNE | NEUROGENE INC | -- | $18,812.01 | 609 | BS2F741 |
| 0.02% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $18,785.40 | 717 | BQD3J33 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,354.00 | 2,622 | BJDX8Z9 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,686.24 | 1,144 | B9L5200 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,582.76 | 2,873 | BQ6C357 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,484.75 | 4,275 | BMXNGZ6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $16,630.34 | 3,074 | BLN9Z50 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,474.10 | 10,910 | BM8NHS1 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,366.35 | 1,199 | BPRBTY7 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,128.64 | 2,552 | BDRJH21 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $16,110.95 | 11,890 | B4N8MH9 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $16,070.40 | 837 | BTNMG41 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $16,030.80 | 584 | B292NQ7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,350.84 | 4,276 | BDFKQ07 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,233.70 | 4,930 | BFY7DC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,665.53 | 2,339 | B12W3P6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,470.16 | 3,788 | BK5MWR1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,412.00 | 1,200 | BM7V485 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,287.14 | 2,001 | B7F2TY6 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,257.33 | 1,849 | BL5B6Z1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,119.60 | 2,523 | BMVBZF5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,831.00 | 2,820 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,482.00 | 7,900 | BFMLGR4 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $12,306.47 | 6,581 | BN4JN37 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,297.69 | 1,231 | BQV0J03 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,179.14 | 3,842 | BKX9NQ0 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $12,162.48 | 3,252 | BDDVW37 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,826.00 | 3,650 | BYTYP72 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,762.64 | 3,844 | BZ8FPH3 |
| 0.02% | CHRS | COHERUS ONCOLOGY INC | -- | $11,477.70 | 5,886 | BRK0149 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $11,215.29 | 3,963 | BZC0D70 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,570.00 | 1,510 | BP81RK8 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,980.65 | 2,305 | BMF7DT9 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,662.57 | 1,119 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,566.64 | 2,322 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $9,462.22 | 5,666 | BN13S71 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,423.40 | 3,556 | B5LL2C2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,389.49 | 1,221 | BP2NYN2 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $9,279.90 | 4,419 | BKRRKY7 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,688.02 | 2,222 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,563.40 | 1,822 | BKDQKM6 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $8,518.78 | 8,535 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,027.67 | 2,107 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,601.00 | 7,601 | BMYTJP4 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,468.37 | 3,679 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,095.41 | 7,694 | BNR5QT9 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $6,745.75 | 2,453 | BLBR8D5 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,628.50 | 1,473 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,591.48 | 2,242 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,048.54 | 2,922 | BPTK6Z2 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,907.76 | 858 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,603.60 | 2,708 | BMTX3D7 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,109.87 | 3,841 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,085.90 | 9,111 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 37.71% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,586,456 | -- | 4,820 | -- |
| 27.57% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,900,139 | -- | 3,524 | -- |
| 26.40% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,010,519 | -- | 3,374 | -- |
| 20.65% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,651,381 | -- | 2,639 | -- |
| 17.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,053,691 | -- | 2,201 | -- |
| 4.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,754,196 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,638,562.04 | 26,638,562 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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