BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -1.49% | -14.47% | -20.30% | -6.07% | -4.31% | -1.10% | -4.38% | -4.22% | 13.18% | 04/07/2010 |
| BIB NAV | -1.28% | -14.31% | -20.40% | -5.95% | -4.14% | -1.07% | -4.38% | -4.22% | 13.19% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -12.17% | -4.65% | -23.66% | -4.65% | -14.82% | -7.50% | 1.19% | -4.67% | 13.38% | 04/07/2010 |
| BIB NAV | -12.25% | -4.72% | -23.81% | -4.72% | -14.95% | -7.45% | 1.07% | -4.69% | 13.36% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 6/03/2025- NAV $45.27
- NAV Change $+0.87
- Market Price $45.32
- Market Price Change $+0.89
- Trading Volume (M) 11,254
- 30-Day Median Bid Ask Spread 0.29%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 6/03/2025- NAV $45.27
- NAV Change $+0.87
- Market Price $45.32
- Market Price Change $+0.89
- Trading Volume (M) 11,254
- 30-Day Median Bid Ask Spread 0.29%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2025
Holdings
as of 6/03/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.05% | GILD | GILEAD SCIENCES INC | -- | $2,821,369.98 | 25,806 | 2369174 |
| 5.95% | AMGN | AMGEN INC | -- | $2,772,922.32 | 9,576 | 2023607 |
| 5.89% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,744,959.04 | 6,148 | 2931034 |
| 4.14% | REGN | REGENERON PHARMACEUTICALS | -- | $1,929,486.30 | 3,955 | 2730190 |
| 3.30% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,538,456.22 | 21,421 | 2989044 |
| 3.10% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,446,552.74 | 4,762 | B00FWN1 |
| 1.52% | BIIB | BIOGEN INC | -- | $709,958.40 | 5,385 | 2455965 |
| 1.46% | ARGX | ARGENX SE - ADR | -- | $679,246.58 | 1,178 | BDVLM39 |
| 1.20% | SMMT | SUMMIT THERAPEUTICS INC | -- | $559,544.32 | 27,136 | BMTVQS7 |
| 1.15% | UTHR | UNITED THERAPEUTICS CORP | -- | $535,578.40 | 1,652 | 2430412 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $530,642.60 | 15,940 | BMVP7Y0 |
| 1.12% | SNY | SANOFI-ADR | -- | $519,938.30 | 10,570 | 2964557 |
| 1.04% | INSM | INSMED INC | -- | $486,566.64 | 6,658 | 2614487 |
| 1.02% | INCY | INCYTE CORP | -- | $477,756.09 | 7,119 | 2471950 |
| 1.02% | ILMN | ILLUMINA INC | -- | $476,823.41 | 5,827 | 2613990 |
| 0.98% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $458,500.00 | 3,668 | 2623911 |
| 0.94% | EXEL | EXELIXIS INC | -- | $439,330.32 | 10,296 | 2576941 |
| 0.91% | BNTX | BIONTECH SE-ADR | -- | $423,242.40 | 3,660 | BK6H543 |
| 0.85% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $398,552.22 | 7,018 | 2437071 |
| 0.85% | MRNA | MODERNA INC | -- | $394,707.33 | 14,193 | BGSXTS3 |
| 0.83% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $387,516.80 | 2,222 | BV9G6B8 |
| 0.83% | ONC | BEONE MEDICINES LTD-ADR | -- | $387,397.08 | 1,539 | BYYWPW6 |
| 0.82% | VTRS | VIATRIS INC | -- | $382,464.81 | 43,911 | BMWS3X9 |
| 0.82% | TEM | TEMPUS AI INC | -- | $380,992.04 | 6,149 | BSLSJJ0 |
| 0.74% | MEDP | MEDPACE HOLDINGS INC | -- | $343,104.47 | 1,121 | BDCBC61 |
| 0.64% | BPMC | BLUEPRINT MEDICINES CORP | -- | $299,987.60 | 2,351 | BWY52P3 |
| 0.63% | ROIV | ROIVANT SCIENCES LTD | -- | $295,170.01 | 26,249 | BMW4NZ9 |
| 0.60% | RVMD | REVOLUTION MEDICINES INC | -- | $277,526.62 | 6,839 | BL71K91 |
| 0.56% | BBIO | BRIDGEBIO PHARMA INC | -- | $262,489.92 | 6,996 | BK1KWG8 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $246,454.88 | 2,234 | B4Q5ZN4 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $245,864.19 | 2,899 | BYWPZK5 |
| 0.52% | HALO | HALOZYME THERAPEUTICS INC | -- | $241,494.30 | 4,530 | 2975098 |
| 0.50% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $230,940.92 | 812 | BD59BS7 |
| 0.45% | GH | GUARDANT HEALTH INC | -- | $207,886.60 | 4,540 | BFXC911 |
| 0.44% | IONS | IONIS PHARMACEUTICALS INC | -- | $203,276.48 | 5,848 | BDJ0LS6 |
| 0.42% | AXSM | AXSOME THERAPEUTICS INC | -- | $197,537.34 | 1,794 | BYZR4X4 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $190,290.12 | 2,434 | BMVBZD3 |
| 0.40% | ALKS | ALKERMES PLC | -- | $187,057.14 | 5,982 | B3P6D26 |
| 0.38% | ADMA | ADMA BIOLOGICS INC | -- | $177,920.16 | 8,696 | B9NSBM2 |
| 0.35% | PCVX | VAXCYTE INC | -- | $164,137.05 | 4,737 | BKPVGH6 |
| 0.34% | MRUS | MERUS NV | -- | $158,671.64 | 2,542 | BZBY005 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $152,748.42 | 2,326 | BF2YWG4 |
| 0.33% | RNA | AVIDITY BIOSCIENCES INC | -- | $152,161.02 | 4,422 | BMWHPY1 |
| 0.32% | AKRO | AKERO THERAPEUTICS INC | -- | $151,165.69 | 2,929 | BK7Y2V9 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $147,051.69 | 2,901 | B17VCN9 |
| 0.30% | CYTK | CYTOKINETICS INC | -- | $139,392.00 | 4,356 | BBBSBJ5 |
| 0.30% | KRYS | KRYSTAL BIOTECH INC | -- | $138,764.60 | 1,060 | BD6JX35 |
| 0.30% | SRPT | SAREPTA THERAPEUTICS INC | -- | $138,727.03 | 3,569 | B8DPDT7 |
| 0.29% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $134,847.30 | 6,135 | 2713317 |
| 0.28% | ACLX | ARCELLX INC | -- | $131,647.94 | 2,021 | BPCJ1Q2 |
| 0.28% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $128,889.75 | 2,757 | BGMGM89 |
| 0.27% | ALVO | ALVOTECH SA | -- | $126,980.50 | 11,090 | BPNTJ34 |
| 0.27% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $123,869.20 | 3,403 | BJ62Z18 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $120,016.20 | 3,155 | BDHF4K6 |
| 0.25% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $115,293.48 | 2,258 | BDCBCD8 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $109,878.30 | 3,423 | BDD19F8 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $107,764.02 | 3,483 | BFZQ0L8 |
| 0.22% | KYMR | KYMERA THERAPEUTICS INC | -- | $104,112.62 | 2,389 | BMPRZV5 |
| 0.21% | IMVT | IMMUNOVANT INC | -- | $96,484.56 | 6,249 | BJRFSB7 |
| 0.19% | APLS | APELLIS PHARMACEUTICALS INC | -- | $86,891.94 | 4,617 | BYTQ6X1 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $86,507.52 | 2,816 | BRJ3GY4 |
| 0.18% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $86,017.53 | 7,687 | 2100362 |
| 0.18% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $85,432.15 | 3,005 | BMX9K07 |
| 0.18% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $84,944.90 | 11,402 | BFNF1D6 |
| 0.18% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $81,657.87 | 1,803 | BJDX8Y8 |
| 0.17% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $77,053.79 | 4,639 | BYQBFJ8 |
| 0.16% | VCEL | VERICEL CORP | -- | $76,405.66 | 1,838 | BSBMN89 |
| 0.16% | VCYT | VERACYTE INC | -- | $75,975.50 | 2,867 | BFTWZY0 |
| 0.16% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $75,507.60 | 4,040 | BP8JSP4 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $75,038.79 | 2,801 | BRBCSP4 |
| 0.16% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,504.10 | 2,110 | BKSGZN7 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $74,414.06 | 5,342 | BD2B4V0 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $72,790.60 | 26,860 | BNSP0B8 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $72,483.95 | 2,345 | BL55460 |
| 0.16% | LGND | LIGAND PHARMACEUTICALS | -- | $72,463.80 | 708 | 2501578 |
| 0.15% | ZLAB | ZAI LAB LTD-ADR | -- | $71,630.13 | 2,301 | BD9GVY0 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $70,750.52 | 11,302 | B19FQ48 |
| 0.15% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $70,343.96 | 2,108 | BCBVTX1 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $69,680.80 | 3,220 | BK0VHF6 |
| 0.15% | NVCR | NOVOCURE LTD | -- | $68,892.72 | 4,043 | BYSS4X4 |
| 0.15% | TWST | TWIST BIOSCIENCE CORP | -- | $67,750.72 | 2,194 | BGKG6G7 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $66,168.19 | 2,053 | B72ZBG4 |
| 0.14% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $63,799.87 | 14,533 | BM9FJ13 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $62,000.92 | 1,412 | BMH5RL1 |
| 0.13% | APGE | APOGEE THERAPEUTICS INC | -- | $61,404.48 | 1,656 | BM9HHL5 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $60,292.80 | 1,272 | BMGJZJ8 |
| 0.12% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $57,910.28 | 4,364 | BKX9VD3 |
| 0.12% | INDV | INDIVIOR PLC | -- | $57,886.73 | 4,567 | BP0BQQ5 |
| 0.12% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $56,337.12 | 1,458 | BLCD809 |
| 0.12% | JANX | JANUX THERAPEUTICS INC | -- | $55,284.82 | 2,174 | BMFX8Y7 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $55,216.47 | 4,161 | BN15WD1 |
| 0.12% | ETNB | 89BIO INC | -- | $54,612.90 | 5,370 | BK1K484 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $53,964.26 | 5,429 | BJ5FZ74 |
| 0.11% | BEAM | BEAM THERAPEUTICS INC | -- | $51,973.52 | 3,079 | BK6L288 |
| 0.11% | SPRY | ARS PHARMACEUTICALS INC | -- | $51,944.75 | 3,575 | BMCR7V2 |
| 0.11% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $51,687.72 | 3,483 | BKY5JZ8 |
| 0.11% | TVTX | TRAVERE THERAPEUTICS INC | -- | $50,265.60 | 3,264 | BLFGJD5 |
| 0.11% | ANIP | ANI PHARMACEUTICALS INC | -- | $49,389.66 | 801 | BCDWBX6 |
| 0.11% | MNKD | MANNKIND CORP | -- | $49,362.56 | 11,168 | BF081J4 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $48,172.39 | 5,783 | BNZB1X8 |
| 0.10% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $48,158.24 | 2,192 | BQS9486 |
| 0.10% | GRAL | GRAIL INC | -- | $47,647.80 | 1,236 | BSLSSX7 |
| 0.10% | INVA | INNOVIVA INC | -- | $47,503.60 | 2,306 | BDDXF67 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $46,011.69 | 1,769 | BNFWZS4 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $45,685.64 | 4,564 | BRJZSK0 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $44,974.95 | 1,545 | BRXB0C0 |
| 0.10% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,932.80 | 1,702 | B3X26D8 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $44,862.88 | 3,358 | BLB0YQ9 |
| 0.09% | NVAX | NOVAVAX INC | -- | $42,957.42 | 5,917 | BJDQXG4 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $40,416.00 | 5,052 | BFWLC09 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $39,282.42 | 1,797 | BMFD115 |
| 0.08% | CVAC | CUREVAC NV | -- | $38,789.10 | 8,253 | BN4RD42 |
| 0.08% | HROW | HARROW INC | -- | $38,435.40 | 1,310 | BHNDW86 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $37,429.92 | 4,488 | B8K7T65 |
| 0.08% | GERN | GERON CORP | -- | $36,783.53 | 23,429 | 2370381 |
| 0.08% | SYRE | SPYRE THERAPEUTICS INC | -- | $36,735.69 | 2,217 | BQBBDY8 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $36,471.50 | 5,611 | BYZG9R0 |
| 0.08% | TXG | 10X GENOMICS INC-CLASS A | -- | $36,276.02 | 3,982 | BKS3RS7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $35,152.30 | 3,140 | BN7Q7R7 |
| 0.07% | ARDX | ARDELYX INC | -- | $34,458.24 | 8,768 | BN89V40 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $33,848.34 | 1,158 | BX7RSN3 |
| 0.07% | NRIX | NURIX THERAPEUTICS INC | -- | $33,727.36 | 2,792 | BMVLGP2 |
| 0.07% | AVDL | AVADEL PHARMACEUTICALS | -- | $33,429.35 | 3,545 | BDGMC59 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $32,921.70 | 1,542 | BBC9WC7 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $30,610.72 | 2,534 | BPCQZY9 |
| 0.07% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $30,570.40 | 742 | BQ721R4 |
| 0.06% | QURE | UNIQURE NV | -- | $30,153.24 | 1,989 | BJFSR88 |
| 0.06% | LENZ | LENZ THERAPEUTICS INC | -- | $30,127.24 | 1,012 | BQV0J03 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $29,657.94 | 1,833 | BP9N0G0 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $29,283.52 | 3,808 | BYZM6C2 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $28,668.80 | 1,240 | BMGTLY5 |
| 0.06% | CRMD | CORMEDIX INC | -- | $28,145.52 | 2,232 | BJ0LT31 |
| 0.06% | REPL | REPLIMUNE GROUP INC | -- | $27,281.79 | 2,833 | BDDVW37 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $26,530.56 | 1,128 | BDRW1L7 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $26,385.35 | 5,045 | BK4PZ38 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $26,021.44 | 3,728 | BLB0YH0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $25,500.60 | 5,484 | BLR7H87 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $25,322.22 | 10,962 | BL53SR3 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $24,531.36 | 3,129 | BYTYP72 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $24,270.30 | 1,818 | BD06CS0 |
| 0.05% | COGT | COGENT BIOSCIENCES INC | -- | $24,248.52 | 4,188 | BLR6XK8 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $24,049.95 | 6,971 | BZ0QMB7 |
| 0.05% | XNCR | XENCOR INC | -- | $23,690.88 | 2,592 | BGCYWN8 |
| 0.05% | EOLS | EVOLUS INC | -- | $23,196.84 | 2,329 | BDRJH21 |
| 0.05% | KROS | KEROS THERAPEUTICS INC | -- | $22,305.40 | 1,492 | BM7V485 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $21,951.02 | 12,061 | BF0DMK7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $21,949.20 | 2,613 | BKVDFF7 |
| 0.05% | STOK | STOKE THERAPEUTICS INC | -- | $21,233.20 | 1,948 | BJQ05Z6 |
| 0.04% | TSHA | TAYSHA GENE THERAPIES INC | -- | $20,963.98 | 7,541 | BNC1BX1 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $20,747.62 | 2,698 | BPQYY97 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $20,516.44 | 6,236 | BN2R582 |
| 0.04% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $20,389.32 | 2,511 | BMGS7L1 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $20,116.08 | 1,809 | BMNDK09 |
| 0.04% | TRVI | TREVI THERAPEUTICS INC | -- | $19,557.65 | 3,287 | BJH9ZN0 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $19,281.92 | 2,152 | BM90J52 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $19,218.42 | 8,213 | BMFJJ97 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $19,073.82 | 2,971 | BYZD465 |
| 0.04% | RGNX | REGENXBIO INC | -- | $18,466.99 | 1,823 | BZ0G875 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $18,101.60 | 748 | BL95N25 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $17,958.65 | 1,861 | BMVNDH9 |
| 0.04% | ARVN | ARVINAS INC | -- | $17,710.00 | 2,530 | BDZ30Q0 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $17,528.79 | 1,049 | BKLCWZ3 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $17,411.81 | 1,963 | BLFBZ32 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $17,388.92 | 943 | BQ80NC6 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $16,772.70 | 1,141 | BYXV9H7 |
| 0.04% | RAPP | RAPPORT THERAPEUTICS INC | -- | $16,475.04 | 1,346 | BR3T9B6 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $16,441.38 | 1,377 | BKVF0J2 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,287.40 | 2,627 | 2107437 |
| 0.03% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $16,138.24 | 3,152 | BPCK358 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $15,927.50 | 2,875 | BFYQFJ2 |
| 0.03% | PSNL | PERSONALIS INC | -- | $15,845.36 | 3,247 | BJQ0608 |
| 0.03% | VERV | VERVE THERAPEUTICS INC | -- | $15,807.44 | 3,266 | BNKGXX2 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $15,408.32 | 538 | B292NQ7 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $15,354.86 | 2,833 | BFY7DC4 |
| 0.03% | FTRE | FORTREA HOLDINGS INC | -- | $15,279.00 | 3,300 | BRXYZ57 |
| 0.03% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $15,260.04 | 7,372 | BFMLGR4 |
| 0.03% | SVRA | SAVARA INC | -- | $15,151.20 | 6,313 | BYXGN81 |
| 0.03% | ERAS | ERASCA INC | -- | $15,028.00 | 10,400 | BNLYBF3 |
| 0.03% | SAGE | SAGE THERAPEUTICS INC | -- | $14,770.86 | 2,262 | BP4GNK9 |
| 0.03% | PGEN | PRECIGEN INC | -- | $14,651.28 | 10,773 | BKM5C84 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $13,574.40 | 1,344 | BMWXFT4 |
| 0.03% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $13,446.00 | 1,620 | BKDQKM6 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $13,212.72 | 648 | BQD3J33 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $13,198.05 | 1,251 | BQS7491 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $12,948.00 | 996 | BKC9SX3 |
| 0.03% | TNGX | TANGO THERAPEUTICS INC | -- | $12,885.48 | 3,977 | BP2P6L0 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $12,641.04 | 543 | BPBPCG8 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $12,449.25 | 2,515 | BJLKVS6 |
| 0.03% | HUMA | HUMACYTE INC | -- | $12,353.13 | 4,733 | BMYTJP4 |
| 0.03% | ALMS | ALUMIS INC | -- | $12,147.45 | 3,521 | BPLQG36 |
| 0.03% | ABSI | ABSCI CORP | -- | $11,745.50 | 4,225 | BN94K69 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $11,634.54 | 1,838 | BP81R42 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,609.12 | 3,922 | BDFKQ07 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,583.96 | 5,218 | BMCWKZ2 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $11,395.92 | 1,383 | BP81RK8 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $11,275.75 | 1,961 | BP7L561 |
| 0.02% | NGNE | NEUROGENE INC | -- | $11,225.76 | 546 | BS2F741 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $11,060.55 | 2,731 | BMZ4LN0 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $10,921.88 | 3,125 | BMDJ0C9 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $10,665.72 | 3,354 | BYVQJ96 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $10,577.70 | 10,074 | B4N8MH9 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,486.40 | 2,260 | BP7KZP7 |
| 0.02% | CMPS | COMPASS PATHWAYS PLC | -- | $10,483.56 | 2,284 | BMC3HS7 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $10,412.55 | 7,713 | BFZNYB7 |
| 0.02% | ATXS | ASTRIA THERAPEUTICS INC | -- | $10,296.96 | 2,076 | BMYRFN8 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $10,004.54 | 3,107 | BLN9Z50 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $9,824.50 | 2,807 | BQHN6C7 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $9,739.68 | 2,364 | BYP80F1 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $9,563.40 | 1,980 | B91XRN2 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,416.55 | 2,145 | B12W3P6 |
| 0.02% | INZY | INOZYME PHARMA INC | -- | $9,404.74 | 2,363 | BMVLGY1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,359.30 | 1,730 | BL5B6Z1 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $9,256.50 | 935 | BQB9HM8 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,018.30 | 3,921 | BMVV9R5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,920.56 | 2,046 | BMF7DT9 |
| 0.02% | MXCT | MAXCYTE INC | -- | $8,846.40 | 3,880 | BKMQF66 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $8,807.15 | 737 | BN72KB0 |
| 0.02% | THRD | THIRD HARMONIC BIO INC | -- | $8,704.50 | 1,658 | BNNPQY8 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $8,425.19 | 13,331 | BWFZX59 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $8,352.83 | 2,083 | BMFK3H6 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $8,241.92 | 6,439 | BPG5P75 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $8,025.76 | 1,648 | BG31GH0 |
| 0.02% | URGN | UROGEN PHARMA LTD | -- | $7,760.00 | 1,552 | BZ7PJQ1 |
| 0.02% | CRGX | CARGO THERAPEUTICS INC | -- | $7,618.50 | 1,693 | BQHN2F2 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $7,610.40 | 7,248 | BBNBTD2 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $7,211.49 | 533 | BNSP8K3 |
| 0.02% | CDXS | CODEXIS INC | -- | $7,129.98 | 3,047 | B5LL2C2 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $7,087.85 | 1,841 | BYX2Z16 |
| 0.01% | OMER | OMEROS CORP | -- | $6,694.48 | 2,132 | B4NB858 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $6,590.61 | 1,703 | BKLXFX5 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,589.52 | 2,009 | BY7RB53 |
| 0.01% | PRME | PRIME MEDICINE INC | -- | $6,417.25 | 4,825 | BPBJFM7 |
| 0.01% | OABI | OMNIAB INC | -- | $6,099.24 | 4,452 | BN13S71 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $6,002.70 | 3,638 | BZC0D70 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $5,698.40 | 4,190 | BCZS820 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $5,656.27 | 2,347 | BMXNGZ6 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,644.15 | 785 | B9L5200 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $5,527.34 | 3,037 | BZ8FPH3 |
| 0.01% | ALEC | ALECTOR INC | -- | $5,394.60 | 3,645 | BJ4LDC4 |
| 0.01% | NKTX | NKARTA INC | -- | $4,594.92 | 2,596 | BK80YJ8 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $4,430.52 | 1,588 | BSMLR16 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $4,416.24 | 5,943 | BN4JN37 |
| 0.01% | -- | LYELL IMMUNOPHARMA INC COMMON STOCK USD 0.0001 | -- | $4,290.63 | 537 | -- |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $3,864.28 | 2,611 | BKX9NQ0 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $3,590.48 | 5,887 | B3MZ6K5 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,582.40 | 2,239 | BMDWW66 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,486.59 | 2,309 | BFDV8K0 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $3,429.12 | 1,216 | BQ6C357 |
| 0.01% | BMEA | BIOMEA FUSION INC | -- | $3,319.17 | 1,333 | BNKF6N0 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $3,190.17 | 2,473 | BMW5LX6 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,160.50 | 1,806 | BNLYBJ7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $2,888.16 | 2,188 | BLBR8D5 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,770.04 | 3,033 | BF12XC2 |
| -- | PEPG | PEPGEN INC | -- | $1,840.59 | 1,203 | BMTX3D7 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $1,743.30 | 894 | BMF1LJ7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,584.95 | 4,544 | BF3NP05 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $1,567.50 | 1,254 | BKS3SM8 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $1,523.68 | 4,280 | BJL38Z1 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,328.20 | 1,145 | BP2TPK4 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,250.85 | 465 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $860.16 | 448 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 34.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 16,171,213 | -- | 3,863 | -- |
| 27.85% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 12,985,530 | -- | 3,102 | -- |
| 18.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 8,497,945 | -- | 2,030 | -- |
| 17.23% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 8,033,279 | -- | 1,919 | -- |
| 15.94% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 7,430,470 | -- | 1,775 | -- |
| 13.79% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 6,429,972 | -- | 1,536 | -- |
| -- | -- | TREASURY BILL | -- | $6,989,393.46 | 7,000,000 | BSNQ2D7 |
| -- | -- | TREASURY BILL | -- | $4,491,575.01 | 4,500,000 | BRBYPQ0 |
| -- | -- | TREASURY BILL | -- | $1,496,494.01 | 1,500,000 | BQ7YG75 |
| -- | -- | TREASURY BILL | -- | $748,070.60 | 750,000 | BS60BF1 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $-723,002.91 | -723,003 | -- |
Index
as of 3/31/2025
- Total Number of Companies264
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.80 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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