BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,354,266
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/18/2026- NAV
- NAV Change
- Market Price $77.26
- Market Price Change $-3.01
- Trading Volume (M) 12,242
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,354,266
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/18/2026- NAV
- NAV Change
- Market Price $77.26
- Market Price Change $-3.01
- Trading Volume (M) 12,242
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/18/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.10% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,589,124.18 | 8,221 | 2931034 |
| 5.05% | GILD | GILEAD SCIENCES INC | -- | $3,555,810.74 | 27,422 | 2369174 |
| 4.85% | AMGN | AMGEN INC | -- | $3,413,555.97 | 10,523 | 2023607 |
| 3.69% | REGN | REGENERON PHARMACEUTICALS | -- | $2,596,800.32 | 4,124 | 2730190 |
| 2.14% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,506,925.28 | 5,264 | B00FWN1 |
| 1.61% | RVMD | REVOLUTION MEDICINES INC | -- | $1,135,614.42 | 7,866 | BL71K91 |
| 1.59% | BIIB | BIOGEN INC | -- | $1,117,875.75 | 5,825 | 2455965 |
| 1.40% | UTHR | UNITED THERAPEUTICS CORP | -- | $986,562.60 | 1,740 | 2430412 |
| 1.30% | INSM | INSMED INC | -- | $916,775.40 | 8,556 | 2614487 |
| 1.26% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $885,450.35 | 17,005 | BMVP7Y0 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $874,068.76 | 1,126 | BDVLM39 |
| 1.22% | ILMN | ILLUMINA INC | -- | $858,824.19 | 6,069 | 2613990 |
| 1.15% | ROIV | ROIVANT SCIENCES LTD | -- | $811,048.40 | 28,408 | BMW4NZ9 |
| 1.07% | MRNA | MODERNA INC | -- | $754,172.36 | 15,676 | BGSXTS3 |
| 1.07% | VTRS | VIATRIS INC | -- | $754,066.50 | 45,701 | BMWS3X9 |
| 1.07% | INCY | INCYTE CORP | -- | $751,905.81 | 7,899 | 2471950 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $626,324.64 | 3,984 | 2623911 |
| 0.83% | ASND | ASCENDIS PHARMA A/S | -- | $580,792.16 | 2,444 | BWXJHM8 |
| 0.80% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $560,790.65 | 2,443 | B4Q5ZN4 |
| 0.73% | EXEL | EXELIXIS INC | -- | $513,750.72 | 10,308 | 2576941 |
| 0.71% | BBIO | BRIDGEBIO PHARMA INC | -- | $502,637.40 | 7,695 | BK1KWG8 |
| 0.71% | GH | GUARDANT HEALTH INC | -- | $498,005.96 | 5,206 | BFXC911 |
| 0.70% | SMMT | SUMMIT THERAPEUTICS INC | -- | $493,031.52 | 30,776 | BMTVQS7 |
| 0.68% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $475,751.53 | 911 | BD59BS7 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $475,513.64 | 6,557 | BDJ0LS6 |
| 0.67% | MEDP | MEDPACE HOLDINGS INC | -- | $474,095.09 | 1,127 | BDCBC61 |
| 0.66% | AXSM | AXSOME THERAPEUTICS INC | -- | $461,622.00 | 2,030 | BYZR4X4 |
| 0.60% | SNY | SANOFI-ADR | -- | $422,991.10 | 9,715 | 2964557 |
| 0.58% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $411,014.10 | 5,558 | BYQBFJ8 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $402,046.25 | 4,525 | BK6H543 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $379,180.78 | 7,634 | 2437071 |
| 0.53% | ONC | BEONE MEDICINES LTD-ADR | -- | $371,931.21 | 1,269 | BYYWPW6 |
| 0.52% | CYTK | CYTOKINETICS INC | -- | $367,555.02 | 4,889 | BBBSBJ5 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $354,185.65 | 1,105 | BQ721R4 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $338,430.00 | 1,160 | BD6JX35 |
| 0.46% | IBRX | IMMUNITYBIO INC | -- | $326,464.00 | 40,808 | BNSP0B8 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $315,888.96 | 4,684 | 2975098 |
| 0.43% | TEM | TEMPUS AI INC-CL A | -- | $300,803.52 | 6,896 | BSLSJJ0 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $290,209.50 | 2,905 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $276,948.45 | 2,439 | BLC89B2 |
| 0.39% | PCVX | VAXCYTE INC | -- | $276,737.72 | 5,713 | BKPVGH6 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $258,210.47 | 3,241 | BMPRZV5 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $255,174.42 | 2,533 | BDCBCD8 |
| 0.35% | ALKS | ALKERMES PLC | -- | $246,011.85 | 6,615 | B3P6D26 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $235,336.40 | 2,710 | BF2YWG4 |
| 0.33% | PTCT | PTC THERAPEUTICS INC | -- | $230,512.90 | 3,286 | B17VCN9 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $228,698.55 | 2,395 | BJDX8Y8 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $218,439.36 | 3,117 | BQBBDY8 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $214,335.87 | 8,079 | BJRFSB7 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $210,878.43 | 3,351 | BRBCSP4 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $202,021.12 | 6,442 | BLR6XK8 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $191,841.62 | 4,049 | BFZQ0L8 |
| 0.27% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $188,171.08 | 4,747 | BLB0YQ9 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $185,013.60 | 3,810 | BDHF4K6 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $181,384.56 | 4,964 | BTZRLN8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $177,350.42 | 3,302 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $171,360.00 | 2,176 | BM9HHL5 |
| 0.24% | CAI | CARIS LIFE SCIENCES INC | -- | $169,104.90 | 11,199 | BT18HP9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $164,648.88 | 792 | 2501578 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $157,020.29 | 3,661 | BLFGJD5 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $155,814.96 | 4,564 | BP8JSP4 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $148,856.96 | 12,488 | BFNF1D6 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $144,213.20 | 4,156 | BDD19F8 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $140,009.23 | 6,767 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $135,063.76 | 4,258 | BKY5JZ8 |
| 0.19% | VCYT | VERACYTE INC | -- | $130,891.00 | 3,154 | BFTWZY0 |
| 0.18% | ERAS | ERASCA INC | -- | $126,197.76 | 12,288 | BNLYBF3 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $121,188.86 | 2,434 | BGKG6G7 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $115,828.00 | 6,295 | BD2B4V0 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $112,071.14 | 1,921 | BKVF0J2 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $111,652.12 | 3,092 | BQS9486 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $110,287.98 | 5,346 | BP2P6L0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $109,999.08 | 2,276 | B72ZBG4 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $108,392.83 | 4,043 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $108,088.90 | 6,535 | BN15WD1 |
| 0.15% | ALMS | ALUMIS INC | -- | $106,130.70 | 5,018 | BPLQG36 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $106,102.98 | 1,689 | BMH5RL1 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $101,277.75 | 1,515 | BMGJZJ8 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $100,192.95 | 4,671 | BKS3RS7 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $98,723.52 | 3,486 | BK0VHF6 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $98,607.69 | 4,923 | BKX9VD3 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $97,732.08 | 1,822 | BRXB0C0 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $97,279.20 | 2,832 | BL55460 |
| 0.13% | GRAL | GRAIL INC | -- | $93,918.37 | 1,547 | BSLSSX7 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $93,368.28 | 2,356 | BMFD115 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $92,768.65 | 3,835 | BJ62Z18 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $90,383.00 | 3,350 | BMX9K07 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $89,296.35 | 9,955 | 2100362 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $85,837.40 | 7,094 | BN2R582 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $84,853.46 | 2,423 | BFXC933 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $82,890.99 | 3,141 | BP9N0G0 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $82,336.80 | 5,278 | BFWLC09 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $81,039.36 | 3,957 | BV2DHY6 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $79,216.14 | 9,453 | B9NSBM2 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $78,866.82 | 4,517 | BYSS4X4 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $77,683.52 | 6,112 | BJ5FZ74 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $75,527.88 | 2,118 | BMVNDH9 |
| 0.10% | PHVS | PHARVARIS NV | -- | $73,263.83 | 2,543 | BMZ2X38 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $72,557.10 | 2,970 | BPCQZY9 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $72,411.58 | 8,641 | BNZB1X8 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $70,744.59 | 4,159 | B8DPDT7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $70,612.60 | 890 | BCDWBX6 |
| 0.10% | VCEL | VERICEL CORP | -- | $70,263.05 | 2,015 | BSBMN89 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $69,494.04 | 1,771 | BQKXDX4 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,489.68 | 2,296 | BKSGZN7 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $68,358.70 | 5,090 | BJH9ZN0 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $67,954.41 | 3,501 | BN7Q7R7 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $67,375.35 | 2,555 | BBC9WC7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $66,560.56 | 1,892 | BR3T9B6 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $65,811.01 | 2,267 | BJQ05Z6 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $65,616.46 | 2,326 | BCBVTX1 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $64,555.26 | 1,099 | BDRW1L7 |
| 0.09% | INVA | INNOVIVA INC | -- | $64,092.00 | 2,940 | BDDXF67 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $63,311.82 | 4,082 | BMVLGP2 |
| 0.09% | QURE | UNIQURE NV | -- | $61,651.89 | 2,473 | BJFSR88 |
| 0.09% | INBX | INHIBRX BIOSCIENCES INC | -- | $61,046.60 | 577 | BNSP8K3 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $59,872.13 | 20,717 | BM9FJ13 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $59,830.55 | 14,417 | BWJDYK1 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $59,503.41 | 4,689 | BYZM6C2 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,474.74 | 9,734 | BN89V40 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,198.04 | 10,872 | BNC1BX1 |
| 0.08% | NVAX | NOVAVAX INC | -- | $57,750.31 | 6,467 | BJDQXG4 |
| 0.08% | PGEN | PRECIGEN INC | -- | $57,159.08 | 14,044 | BKM5C84 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $56,056.74 | 4,359 | BPCK358 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $55,433.28 | 16,352 | BF0DMK7 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $55,206.36 | 1,782 | BQXJKH2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,707.26 | 6,238 | BK4PZ38 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,498.26 | 3,026 | BP7KZP7 |
| 0.08% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $53,680.56 | 2,006 | BD06CS0 |
| 0.08% | GHRS | GH RESEARCH PLC | -- | $53,376.16 | 2,462 | BP6C0S2 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $53,101.64 | 1,858 | BZ7PJQ1 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $50,432.49 | 3,711 | BRXYZ57 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,057.28 | 12,033 | BL53SR3 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,392.17 | 1,741 | BLCD809 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $48,514.35 | 2,515 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $47,820.80 | 7,472 | BYZG9R0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $46,795.00 | 1,910 | BSRK699 |
| 0.07% | SEPN | SEPTERNA INC | -- | $46,735.10 | 1,777 | BQNKXX2 |
| 0.06% | HROW | HARROW INC | -- | $45,423.00 | 1,470 | BHNDW86 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,318.56 | 1,639 | BMGTLY5 |
| 0.06% | ALVO | ALVOTECH SA | -- | $42,607.50 | 13,110 | BPNTJ34 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,399.00 | 1,260 | BX7RSN3 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $41,047.80 | 3,182 | BMZ4LN0 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $40,024.38 | 3,278 | BYP80F1 |
| 0.06% | SVRA | SAVARA INC | -- | $39,653.16 | 8,076 | BYXGN81 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $39,581.86 | 6,586 | BLR7H87 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $39,526.08 | 3,743 | BMC3HS7 |
| 0.05% | EYPT | EYEPOINT INC | -- | $38,446.20 | 3,286 | BMGS7L1 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $38,106.54 | 4,842 | B8K7T65 |
| 0.05% | MNKD | MANNKIND CORP | -- | $36,564.71 | 12,229 | BF081J4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $36,061.08 | 1,607 | B3X26D8 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,035.21 | 2,131 | BQB42H3 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $35,627.92 | 3,128 | BJLKVS6 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,870.15 | 2,345 | BM90J52 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $34,569.36 | 1,064 | BGL0JK3 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $33,882.45 | 2,415 | BMFX8Y7 |
| 0.05% | OMER | OMEROS CORP | -- | $32,923.80 | 2,814 | B4NB858 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $32,698.86 | 2,011 | BMNDK09 |
| 0.05% | XNCR | XENCOR INC | -- | $32,195.66 | 2,911 | BGCYWN8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $32,141.92 | 10,573 | BMFJJ97 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,833.78 | 7,634 | BZ0QMB7 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $31,776.80 | 3,454 | BYZD465 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,585.19 | 3,983 | BKVDFF7 |
| 0.04% | GERN | GERON CORP | -- | $31,165.74 | 25,338 | 2370381 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,977.20 | 1,801 | BNFWZS4 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $30,421.92 | 2,078 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,033.00 | 3,195 | BFYQFJ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,700.57 | 9,489 | BBNBTD2 |
| 0.04% | ABSI | ABSCI CORP | -- | $29,516.71 | 5,969 | BN94K69 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $28,645.20 | 3,924 | BMCR7V2 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,495.20 | 5,745 | BMVV9R5 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $27,993.42 | 819 | BL95N25 |
| 0.04% | PSNL | PERSONALIS INC | -- | $27,908.16 | 4,153 | BJQ0608 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,446.16 | 1,724 | BT9K6D8 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $25,668.46 | 1,361 | BD9GVY0 |
| 0.04% | CRMD | CORMEDIX INC | -- | $24,734.57 | 3,127 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $24,192.70 | 2,261 | BMFK3H6 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,704.80 | 5,810 | BMCWKZ2 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $23,537.50 | 6,725 | BYWVTY5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,311.05 | 2,235 | BLFBZ32 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,286.24 | 1,648 | BRJJYT3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,965.30 | 2,907 | BP0TQC5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,797.60 | 1,180 | BKLCWZ3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,652.00 | 6,472 | B3MZ6K5 |
| 0.03% | ARVN | ARVINAS INC | -- | $22,292.42 | 2,539 | BDZ30Q0 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,062.80 | 4,787 | BYV2W40 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,636.50 | 745 | BPBPCG8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,599.20 | 720 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,493.83 | 2,137 | B91XRN2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $20,133.65 | 7,165 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,128.92 | 3,092 | BQHN6C7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,025.81 | 4,843 | BYVQJ96 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $19,551.21 | 1,099 | BS2CR64 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $19,368.72 | 2,268 | BSMLR16 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $18,831.87 | 2,521 | BP81R42 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $18,253.95 | 2,145 | BRCFFK6 |
| 0.03% | KMDA | KAMADA LTD | -- | $17,930.70 | 2,290 | B2Q9833 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,304.80 | 8,920 | BFZNYB7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,207.70 | 615 | BS2F741 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,939.13 | 2,025 | BKLXFX5 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,904.61 | 2,573 | BDRJH21 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $16,417.77 | 3,277 | BDDVW37 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,101.96 | 2,644 | BJDX8Z9 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,693.72 | 588 | B292NQ7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,534.88 | 1,208 | BPRBTY7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,494.40 | 1,152 | B9L5200 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $14,331.60 | 7,962 | BFMLGR4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,263.68 | 2,346 | B12W3P6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,964.40 | 4,310 | BMXNGZ6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,918.80 | 4,971 | BFY7DC4 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,917.93 | 843 | BTNMG41 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,785.05 | 11,987 | B4N8MH9 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,749.39 | 2,019 | B7F2TY6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,644.87 | 2,897 | BQ6C357 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $13,228.63 | 4,309 | BDFKQ07 |
| 0.02% | OABI | OMNIAB INC | -- | $13,085.06 | 5,714 | BN13S71 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,838.14 | 3,101 | BLN9Z50 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,571.09 | 3,821 | BK5MWR1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $12,481.81 | 2,563 | BMVBZF5 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,471.06 | 3,873 | BKX9NQ0 |
| 0.02% | IVVD | INVIVYD INC | -- | $12,430.00 | 11,000 | BM8NHS1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,283.44 | 1,209 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,135.34 | 2,842 | 2107437 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,738.64 | 6,632 | BN4JN37 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,612.72 | 1,864 | BL5B6Z1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,350.85 | 2,009 | BZ0G875 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,060.61 | 3,993 | BZC0D70 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $10,592.64 | 3,678 | BYTYP72 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,803.75 | 3,875 | BZ8FPH3 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,141.75 | 3,585 | B5LL2C2 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,952.80 | 1,520 | BP81RK8 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,919.18 | 2,241 | BPRB2N7 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,881.50 | 2,325 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,840.17 | 5,933 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,569.80 | 1,242 | BQV0J03 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,256.67 | 2,339 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,198.46 | 1,231 | BP2NYN2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,018.04 | 1,839 | BKDQKM6 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,929.84 | 1,128 | BKC9SX3 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,692.50 | 2,125 | BP7L561 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,679.70 | 3,710 | BNYJR68 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,618.05 | 4,455 | BKRRKY7 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,881.74 | 7,660 | BMYTJP4 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,736.93 | 8,604 | BNNXX52 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,627.97 | 7,762 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,513.06 | 1,487 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,833.38 | 2,261 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,746.65 | 2,947 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,991.42 | 2,471 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,011.63 | 2,729 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $3,767.04 | 864 | BTXQTX3 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,764.75 | 3,872 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,770.33 | 9,187 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 29.56% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 20,794,911 | -- | 3,637 | -- |
| 28.64% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,148,822 | -- | 3,524 | -- |
| 27.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,291,182 | -- | 3,374 | -- |
| 21.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,088,746 | -- | 2,639 | -- |
| 20.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,368,329 | -- | 2,513 | -- |
| 5.14% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,619,241 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,007,475.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $17,763,481.17 | 17,763,481 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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