BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,566,678
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/25/2026- NAV $78.78
- NAV Change $+3.93
- Market Price $78.73
- Market Price Change $+3.93
- Trading Volume (M) 13,645
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,566,678
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/25/2026- NAV $78.78
- NAV Change $+3.93
- Market Price $78.73
- Market Price Change $+3.93
- Trading Volume (M) 13,645
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/25/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.50% | GILD | GILEAD SCIENCES INC | -- | $4,333,206.66 | 31,341 | 2369174 |
| 5.43% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,274,898.12 | 9,396 | 2931034 |
| 5.40% | AMGN | AMGEN INC | -- | $4,256,716.11 | 12,027 | 2023607 |
| 4.48% | REGN | REGENERON PHARMACEUTICALS | -- | $3,532,252.11 | 4,713 | 2730190 |
| 2.51% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,977,459.20 | 6,016 | B00FWN1 |
| 1.84% | INSM | INSMED INC | -- | $1,450,175.18 | 9,778 | 2614487 |
| 1.60% | BIIB | BIOGEN INC | -- | $1,259,371.26 | 6,657 | 2455965 |
| 1.37% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,076,700.80 | 1,988 | 2430412 |
| 1.22% | MRNA | MODERNA INC | -- | $959,222.64 | 17,916 | BGSXTS3 |
| 1.16% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $914,028.05 | 19,435 | BMVP7Y0 |
| 1.14% | ARGX | ARGENX SE - ADR | -- | $897,103.35 | 1,287 | BDVLM39 |
| 1.13% | ROIV | ROIVANT SCIENCES LTD | -- | $888,324.48 | 32,468 | BMW4NZ9 |
| 1.11% | ILMN | ILLUMINA INC | -- | $875,449.40 | 6,937 | 2613990 |
| 1.08% | RVMD | REVOLUTION MEDICINES INC | -- | $847,667.10 | 8,990 | BL71K91 |
| 1.06% | INCY | INCYTE CORP | -- | $832,652.44 | 9,028 | 2471950 |
| 0.90% | VTRS | VIATRIS INC | -- | $705,145.50 | 52,233 | BMWS3X9 |
| 0.80% | SMMT | SUMMIT THERAPEUTICS INC | -- | $631,039.50 | 35,175 | BMTVQS7 |
| 0.80% | BBIO | BRIDGEBIO PHARMA INC | -- | $629,809.95 | 8,795 | BK1KWG8 |
| 0.78% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $616,973.70 | 2,793 | BV9G6B8 |
| 0.76% | MEDP | MEDPACE HOLDINGS INC | -- | $600,771.60 | 1,287 | BDCBC61 |
| 0.76% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $597,034.89 | 4,553 | 2623911 |
| 0.69% | IONS | IONIS PHARMACEUTICALS INC | -- | $544,813.80 | 7,494 | BDJ0LS6 |
| 0.67% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $528,100.44 | 2,793 | B4Q5ZN4 |
| 0.65% | GH | GUARDANT HEALTH INC | -- | $515,151.00 | 5,950 | BFXC911 |
| 0.65% | SNY | SANOFI-ADR | -- | $511,071.09 | 11,103 | 2964557 |
| 0.64% | EXEL | EXELIXIS INC | -- | $504,050.09 | 11,781 | 2576941 |
| 0.62% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $485,022.75 | 8,725 | 2437071 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $480,869.13 | 1,041 | BD59BS7 |
| 0.58% | BNTX | BIONTECH SE-ADR | -- | $458,763.36 | 5,168 | BK6H543 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $411,002.50 | 1,450 | BYYWPW6 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $393,954.96 | 1,263 | BQ721R4 |
| 0.49% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $386,071.81 | 6,353 | BYQBFJ8 |
| 0.48% | IBRX | IMMUNITYBIO INC | -- | $376,384.80 | 46,640 | BNSP0B8 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $375,491.38 | 2,321 | BYZR4X4 |
| 0.47% | TEM | TEMPUS AI INC-CL A | -- | $368,515.56 | 7,881 | BSLSJJ0 |
| 0.46% | PCVX | VAXCYTE INC | -- | $365,036.39 | 6,529 | BKPVGH6 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $348,572.93 | 5,587 | BBBSBJ5 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $338,586.96 | 5,354 | 2975098 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $338,318.65 | 1,327 | BD6JX35 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $325,360.00 | 3,320 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $308,520.90 | 2,787 | BLC89B2 |
| 0.39% | ACLX | ARCELLX INC | -- | $303,874.62 | 2,653 | BPCJ1Q2 |
| 0.38% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $301,977.45 | 2,895 | BDCBCD8 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $292,277.79 | 3,703 | BMPRZV5 |
| 0.34% | COGT | COGENT BIOSCIENCES INC | -- | $268,749.50 | 7,363 | BLR6XK8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $262,152.76 | 3,098 | BF2YWG4 |
| 0.32% | TERN | TERNS PHARMACEUTICALS INC | -- | $254,996.64 | 4,824 | BMDJ0C9 |
| 0.32% | CGON | CG ONCOLOGY INC | -- | $252,118.11 | 3,831 | BRBCSP4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $250,646.25 | 3,755 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $246,795.29 | 2,737 | BJDX8Y8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $237,568.00 | 12,800 | BT18HP9 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $228,633.84 | 9,234 | BJRFSB7 |
| 0.29% | ERAS | ERASCA INC | -- | $224,579.55 | 14,045 | BNLYBF3 |
| 0.28% | ALKS | ALKERMES PLC | -- | $222,037.20 | 7,560 | B3P6D26 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $210,250.04 | 4,628 | BFZQ0L8 |
| 0.27% | XENE | XENON PHARMACEUTICALS INC | -- | $209,721.18 | 3,774 | BRJ3GY4 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $205,029.86 | 4,354 | BDHF4K6 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $195,304.11 | 2,487 | BM9HHL5 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $184,922.24 | 904 | 2501578 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $174,999.24 | 14,274 | BFNF1D6 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $172,615.00 | 4,750 | BDD19F8 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,664.98 | 5,673 | BTZRLN8 |
| 0.22% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $170,225.34 | 7,734 | 2713317 |
| 0.22% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $170,091.42 | 3,534 | BQS9486 |
| 0.21% | SYRE | SPYRE THERAPEUTICS INC | -- | $162,757.84 | 3,563 | BQBBDY8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $161,717.15 | 5,215 | BP8JSP4 |
| 0.21% | DNLI | DENALI THERAPEUTICS INC | -- | $161,671.65 | 7,195 | BD2B4V0 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $155,420.04 | 4,866 | BKY5JZ8 |
| 0.19% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $153,121.72 | 5,426 | BLB0YQ9 |
| 0.18% | ALMS | ALUMIS INC | -- | $142,285.35 | 5,735 | BPLQG36 |
| 0.18% | DYN | DYNE THERAPEUTICS INC | -- | $141,761.62 | 7,469 | BN15WD1 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $135,267.84 | 2,781 | BGKG6G7 |
| 0.17% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $130,206.06 | 2,601 | B72ZBG4 |
| 0.17% | VERA | VERA THERAPEUTICS INC | -- | $129,997.92 | 3,237 | BL55460 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $129,232.80 | 1,930 | BMH5RL1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $127,844.28 | 5,622 | BKX9VD3 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $127,576.80 | 6,110 | BP2P6L0 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $125,057.76 | 3,984 | BK0VHF6 |
| 0.15% | VCYT | VERACYTE INC | -- | $118,207.95 | 3,605 | BFTWZY0 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $115,338.60 | 4,185 | BLFGJD5 |
| 0.14% | SRPT | SAREPTA THERAPEUTICS INC | -- | $113,002.58 | 4,754 | B8DPDT7 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $111,617.58 | 5,338 | BKS3RS7 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $108,274.05 | 1,731 | BMGJZJ8 |
| 0.14% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $106,953.20 | 11,378 | 2100362 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $106,837.52 | 4,621 | BK6L288 |
| 0.13% | WVE | WAVE LIFE SCIENCES LTD | -- | $105,042.00 | 8,540 | BYZG9R0 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $104,042.52 | 10,804 | B9NSBM2 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $102,758.28 | 5,799 | BYTQ6X1 |
| 0.13% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $100,139.82 | 4,686 | BLB0YH0 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $98,837.75 | 6,985 | BJ5FZ74 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $96,824.20 | 4,001 | BN7Q7R7 |
| 0.12% | ORKA | ORUKA THERAPEUTICS INC | -- | $96,206.76 | 2,196 | BKVF0J2 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $95,682.29 | 2,693 | BMFD115 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $95,438.88 | 2,082 | BRXB0C0 |
| 0.12% | GRAL | GRAIL INC | -- | $92,448.72 | 1,768 | BSLSSX7 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $88,874.91 | 2,421 | BMVNDH9 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $88,385.80 | 3,590 | BP9N0G0 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $87,549.89 | 2,591 | BJQ05Z6 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $87,022.40 | 4,384 | BJ62Z18 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $86,679.84 | 6,032 | BFWLC09 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $83,539.81 | 4,523 | BV2DHY6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,267.08 | 9,876 | BNZB1X8 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $82,260.85 | 3,395 | BPCQZY9 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $82,195.23 | 1,257 | BDRW1L7 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $78,650.22 | 2,658 | BCBVTX1 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $77,836.80 | 8,108 | BN2R582 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $76,241.20 | 2,920 | BBC9WC7 |
| 0.10% | PHVS | PHARVARIS NV | -- | $75,991.90 | 2,906 | BMZ2X38 |
| 0.10% | INVA | INNOVIVA INC | -- | $75,902.40 | 3,360 | BDDXF67 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,329.19 | 1,017 | BCDWBX6 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $75,087.00 | 2,025 | BQKXDX4 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $75,059.26 | 23,678 | BM9FJ13 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,406.32 | 2,303 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,396.16 | 2,624 | BKSGZN7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $72,027.60 | 4,665 | BMVLGP2 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $71,060.34 | 5,359 | BYZM6C2 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $70,080.00 | 18,688 | BF0DMK7 |
| 0.09% | MAZE | MAZE THERAPEUTICS INC | -- | $69,266.59 | 2,183 | BSRK699 |
| 0.09% | NVAX | NOVAVAX INC | -- | $69,031.94 | 7,391 | BJDQXG4 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $68,901.06 | 4,982 | BPCK358 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $67,390.40 | 3,829 | BMX9K07 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $66,546.48 | 5,817 | BJH9ZN0 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,098.70 | 7,130 | BK4PZ38 |
| 0.08% | KOD | KODIAK SCIENCES INC | -- | $62,994.75 | 2,769 | BFXC933 |
| 0.08% | ARDX | ARDELYX INC | -- | $62,745.00 | 11,125 | BN89V40 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $62,438.56 | 2,162 | BR3T9B6 |
| 0.08% | HROW | HARROW INC | -- | $61,104.35 | 1,681 | BHNDW86 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $60,226.92 | 1,989 | BLCD809 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $59,930.82 | 5,162 | BYSS4X4 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $58,991.52 | 2,037 | BQXJKH2 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $58,328.58 | 16,477 | BWJDYK1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,911.08 | 12,426 | BNC1BX1 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,340.89 | 3,459 | BP7KZP7 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $54,032.65 | 2,435 | BQB42H3 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $53,686.32 | 2,874 | BQB42F1 |
| 0.07% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $53,361.36 | 936 | BL95N25 |
| 0.07% | ORIC | ORIC PHARMACEUTICALS INC | -- | $53,270.10 | 4,553 | BKVDFF7 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,268.12 | 3,746 | BYP80F1 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $51,522.12 | 3,636 | BMZ4LN0 |
| 0.06% | PGEN | PRECIGEN INC | -- | $49,758.10 | 16,051 | BKM5C84 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,170.51 | 2,031 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $49,015.80 | 3,756 | BMGS7L1 |
| 0.06% | SVRA | SAVARA INC | -- | $48,739.68 | 9,231 | BYXGN81 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,913.25 | 1,441 | BX7RSN3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,049.76 | 14,984 | BPNTJ34 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,622.67 | 13,753 | BL53SR3 |
| 0.06% | QURE | UNIQURE NV | -- | $46,233.36 | 2,826 | BJFSR88 |
| 0.06% | GERN | GERON CORP | -- | $45,465.63 | 28,959 | 2370381 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $43,863.60 | 660 | BNSP8K3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,127.64 | 1,836 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $42,667.14 | 5,534 | B8K7T65 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $42,610.75 | 1,873 | BMGTLY5 |
| 0.05% | XNCR | XENCOR INC | -- | $41,254.80 | 3,327 | BGCYWN8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,275.06 | 2,058 | BNFWZS4 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,044.48 | 4,242 | BRXYZ57 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $39,893.10 | 7,527 | BLR7H87 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $39,524.25 | 8,725 | BZ0QMB7 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,302.02 | 2,293 | BD06CS0 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $38,468.76 | 2,123 | BZ7PJQ1 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $38,411.10 | 2,814 | BP6C0S2 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $38,088.00 | 2,760 | BMFX8Y7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,680.80 | 2,680 | BM90J52 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,460.40 | 12,084 | BMFJJ97 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,419.78 | 3,574 | BJLKVS6 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $37,168.75 | 2,375 | BQS7491 |
| 0.05% | PSNL | PERSONALIS INC | -- | $36,551.90 | 4,747 | BJQ0608 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,431.50 | 4,485 | BMCR7V2 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,226.59 | 6,566 | BMVV9R5 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,151.71 | 2,299 | BMNDK09 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $34,089.23 | 1,349 | BKLCWZ3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,746.85 | 3,947 | BYZD465 |
| 0.04% | OMER | OMEROS CORP | -- | $33,575.04 | 3,216 | B4NB858 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,434.92 | 7,686 | BYWVTY5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,344.11 | 1,971 | BT9K6D8 |
| 0.04% | MNKD | MANNKIND CORP | -- | $31,867.56 | 13,977 | BF081J4 |
| 0.04% | ARVN | ARVINAS INC | -- | $31,689.84 | 2,902 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,932.20 | 10,845 | BBNBTD2 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,726.07 | 8,189 | BPBJFM7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $28,989.44 | 1,216 | BGL0JK3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $28,440.95 | 1,555 | BD9GVY0 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $28,319.76 | 3,746 | BDDVW37 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,820.62 | 3,651 | BFYQFJ2 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,726.32 | 2,584 | BMFK3H6 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $26,463.12 | 852 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,558.05 | 3,535 | BQHN6C7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,378.96 | 1,884 | BRJJYT3 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $24,047.98 | 4,279 | BMC3HS7 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $23,754.35 | 10,195 | BFZNYB7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,624.14 | 3,574 | BJ0LT31 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,558.15 | 7,385 | B3MZ6K5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,308.89 | 2,553 | BLFBZ32 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $23,302.35 | 5,535 | BYVQJ96 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,220.44 | 2,452 | BRCFFK6 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $23,053.68 | 4,926 | BMXNGZ6 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $23,053.68 | 4,926 | BDFKQ07 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,862.32 | 2,314 | BKLXFX5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,735.02 | 2,442 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,662.96 | 824 | BQD3J33 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,459.40 | 2,617 | B2Q9833 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $21,086.58 | 3,021 | BJDX8Z9 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,930.85 | 1,737 | BP81RK8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,653.51 | 6,641 | BMCWKZ2 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $20,620.72 | 673 | B292NQ7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,399.04 | 2,592 | BSMLR16 |
| 0.03% | ABSI | ABSCI CORP | -- | $19,917.32 | 6,821 | BN94K69 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,640.89 | 5,471 | BYV2W40 |
| 0.02% | IVVD | INVIVYD INC | -- | $19,610.76 | 12,571 | BM8NHS1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $19,509.75 | 2,691 | B12W3P6 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,424.16 | 2,296 | BZ0G875 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,414.96 | 964 | BTNMG41 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,243.92 | 3,544 | BLN9Z50 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,043.00 | 13,700 | B4N8MH9 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $18,950.00 | 7,580 | BN4JN37 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,938.92 | 3,311 | BQ6C357 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,804.11 | 5,681 | BFY7DC4 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,668.88 | 2,881 | BP81R42 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,339.68 | 1,381 | BPRBTY7 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,546.84 | 3,316 | BP0TQC5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,212.51 | 3,249 | 2107437 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,027.89 | 1,317 | B9L5200 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,671.88 | 1,382 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,486.52 | 2,911 | BMVBZF5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,465.06 | 702 | BS2F741 |
| 0.02% | PEPG | PEPGEN INC | -- | $15,220.72 | 3,119 | BMTX3D7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,609.64 | 2,308 | B7F2TY6 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $13,442.88 | 5,092 | BKRRKY7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,418.16 | 4,564 | BZC0D70 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,099.01 | 2,657 | BMF7DT9 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,870.33 | 1,419 | BQV0J03 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,847.80 | 2,940 | BDRJH21 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,140.26 | 4,367 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,103.00 | 9,100 | BFMLGR4 |
| 0.02% | CHRS | COHERUS ONCOLOGY INC | -- | $12,002.37 | 6,781 | BRK0149 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,905.94 | 4,426 | BKX9NQ0 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,703.77 | 2,561 | BPRB2N7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,651.10 | 2,130 | BL5B6Z1 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,518.96 | 4,204 | BYTYP72 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,776.22 | 2,674 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $10,578.60 | 6,530 | BN13S71 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,272.96 | 4,428 | BZ8FPH3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,837.36 | 2,102 | BKDQKM6 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,100.34 | 1,289 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,971.20 | 4,240 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,668.23 | 8,865 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,381.12 | 2,428 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,205.37 | 8,755 | BMYTJP4 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,171.50 | 4,098 | B5LL2C2 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,118.81 | 1,699 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,103.36 | 9,833 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,037.03 | 3,367 | BPTK6Z2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $6,495.72 | 1,406 | BP2NYN2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,661.15 | 2,585 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,044.50 | 4,425 | BNNXX18 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,039.75 | 2,825 | BLBR8D5 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,005.75 | 10,500 | BJ0CK86 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,493.98 | 987 | BTXQTX3 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $23.50 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 33.31% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 26,241,156 | -- | 4,580 | -- |
| 31.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,539,491 | -- | 4,283 | -- |
| 26.92% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,210,646 | -- | 3,702 | -- |
| 19.19% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,120,177 | -- | 2,639 | -- |
| 14.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,401,725 | -- | 1,990 | -- |
| 4.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,626,780 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $23,414,192.22 | 23,414,192 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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