BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 5/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 3.79% | -3.99% | 1.49% | 6.15% | 98.53% | 18.55% | 0.58% | -- | 16.40% | 04/07/2010 |
| BIB Market Price | 3.64% | -4.03% | 1.26% | 6.04% | 98.32% | 18.49% | 0.55% | -- | 16.40% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,660,238
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/30/2026- NAV
- NAV Change
- Market Price $100.74
- Market Price Change $+0.26
- Trading Volume (M) 14,961
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,660,238
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/30/2026- NAV
- NAV Change
- Market Price $100.74
- Market Price Change $+0.26
- Trading Volume (M) 14,961
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/30/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.56% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,816,376.59 | 7,683 | 2931034 |
| 4.42% | AMGN | AMGEN INC | -- | $3,696,158.84 | 10,207 | 2023607 |
| 3.86% | GILD | GILEAD SCIENCES INC | -- | $3,231,019.16 | 25,574 | 2369174 |
| 2.52% | REGN | REGENERON PHARMACEUTICALS | -- | $2,105,694.58 | 3,377 | 2730190 |
| 1.57% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,317,608.31 | 4,377 | B00FWN1 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,305,341.60 | 6,970 | BL71K91 |
| 1.25% | BIIB | BIOGEN INC | -- | $1,045,946.46 | 4,841 | 2455965 |
| 1.09% | MRNA | MODERNA INC | -- | $911,510.48 | 13,016 | BGSXTS3 |
| 1.04% | ILMN | ILLUMINA INC | -- | $872,644.29 | 4,963 | 2613990 |
| 1.00% | ARGX | ARGENX SE - ADR | -- | $840,559.62 | 906 | BDVLM39 |
| 1.00% | ROIV | ROIVANT SCIENCES LTD | -- | $834,637.76 | 23,584 | BMW4NZ9 |
| 0.97% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $815,369.94 | 14,542 | BMVP7Y0 |
| 0.91% | INSM | INSMED INC | -- | $757,961.58 | 7,109 | 2614487 |
| 0.90% | UTHR | UNITED THERAPEUTICS CORP | -- | $754,227.36 | 1,392 | 2430412 |
| 0.89% | INCY | INCYTE CORP | -- | $742,734.72 | 6,552 | 2471950 |
| 0.78% | GH | GUARDANT HEALTH INC | -- | $652,480.47 | 4,349 | BFXC911 |
| 0.72% | VTRS | VIATRIS INC | -- | $606,409.56 | 38,187 | BMWS3X9 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $555,828.43 | 3,298 | 2623911 |
| 0.64% | ASND | ASCENDIS PHARMA A/S | -- | $539,041.12 | 2,021 | BWXJHM8 |
| 0.59% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $495,916.26 | 2,058 | B4Q5ZN4 |
| 0.59% | MEDP | MEDPACE HOLDINGS INC | -- | $495,166.65 | 935 | BDCBC61 |
| 0.57% | BBIO | BRIDGEBIO PHARMA INC | -- | $478,236.08 | 6,421 | BK1KWG8 |
| 0.54% | EXEL | EXELIXIS INC | -- | $448,501.63 | 8,243 | 2576941 |
| 0.51% | IONS | IONIS PHARMACEUTICALS INC | -- | $429,513.93 | 5,417 | BDJ0LS6 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $412,437.45 | 1,685 | BYZR4X4 |
| 0.49% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $406,471.15 | 757 | BD59BS7 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $378,754.74 | 4,446 | BBBSBJ5 |
| 0.45% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $376,250.16 | 4,616 | BYQBFJ8 |
| 0.44% | SMMT | SUMMIT THERAPEUTICS INC | -- | $370,821.07 | 25,451 | BMTVQS7 |
| 0.43% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $362,545.92 | 6,336 | 2437071 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $360,148.23 | 969 | BD6JX35 |
| 0.42% | BNTX | BIONTECH SE-ADR | -- | $354,706.60 | 3,812 | BK6H543 |
| 0.40% | TEM | TEMPUS AI INC-CL A | -- | $331,417.53 | 5,721 | BSLSJJ0 |
| 0.39% | SNY | SANOFI-ADR | -- | $325,453.14 | 7,629 | 2964557 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $309,379.66 | 2,698 | BMPRZV5 |
| 0.37% | ONC | BEONE MEDICINES LTD-ADR | -- | $308,052.57 | 1,081 | BYYWPW6 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $306,667.64 | 916 | BQ721R4 |
| 0.36% | HALO | HALOZYME THERAPEUTICS INC | -- | $304,392.03 | 3,889 | 2975098 |
| 0.36% | IBRX | IMMUNITYBIO INC | -- | $300,681.72 | 34,344 | BNSP0B8 |
| 0.36% | NUVL | NUVALENT INC-A | -- | $298,129.00 | 2,414 | BMVBZD3 |
| 0.34% | ALKS | ALKERMES PLC | -- | $286,233.89 | 5,463 | B3P6D26 |
| 0.33% | PCVX | VAXCYTE INC | -- | $275,187.42 | 4,734 | BKPVGH6 |
| 0.32% | APGE | APOGEE THERAPEUTICS INC | -- | $269,176.44 | 2,028 | BM9HHL5 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $259,383.96 | 6,732 | BJRFSB7 |
| 0.31% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $258,643.80 | 2,110 | BDCBCD8 |
| 0.30% | ABVX | ABIVAX SA-ADR | -- | $253,327.26 | 1,901 | BLC89B2 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $253,023.00 | 2,850 | BQBBDY8 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $249,706.47 | 2,249 | BF2YWG4 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $234,140.00 | 2,000 | BJDX8Y8 |
| 0.26% | PTCT | PTC THERAPEUTICS INC | -- | $221,625.69 | 2,717 | B17VCN9 |
| 0.26% | COGT | COGENT BIOSCIENCES INC | -- | $216,874.80 | 5,604 | BLR6XK8 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $216,040.00 | 3,928 | BFZQ0L8 |
| 0.25% | TWST | TWIST BIOSCIENCE CORP | -- | $209,978.08 | 2,041 | BGKG6G7 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $207,987.22 | 658 | 2501578 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $205,476.60 | 2,892 | BRBCSP4 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $191,160.12 | 3,167 | BRJ3GY4 |
| 0.22% | ORKA | ORUKA THERAPEUTICS INC | -- | $188,055.92 | 1,976 | BKVF0J2 |
| 0.22% | ERAS | ERASCA INC | -- | $186,845.68 | 10,199 | BNLYBF3 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $181,045.29 | 10,459 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $173,270.50 | 3,050 | BLFGJD5 |
| 0.21% | CRSP | CRISPR THERAPEUTICS AG | -- | $172,564.56 | 3,164 | BDHF4K6 |
| 0.20% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $168,073.92 | 3,573 | BV2DHY6 |
| 0.20% | CAI | CARIS LIFE SCIENCES INC | -- | $165,155.76 | 9,268 | BT18HP9 |
| 0.20% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $164,037.94 | 3,998 | BTZRLN8 |
| 0.18% | VCYT | VERACYTE INC | -- | $153,813.87 | 2,619 | BFTWZY0 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $148,297.44 | 4,744 | BP2P6L0 |
| 0.18% | TXG | 10X GENOMICS INC-CLASS A | -- | $147,302.28 | 3,842 | BKS3RS7 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $143,302.01 | 3,527 | BKY5JZ8 |
| 0.17% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $142,008.90 | 5,613 | 2713317 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $137,287.86 | 2,558 | BQS9486 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $133,872.60 | 5,205 | BD2B4V0 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $131,606.14 | 7,034 | BN2R582 |
| 0.16% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $129,866.48 | 3,832 | BP8JSP4 |
| 0.15% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $129,435.78 | 3,459 | BDD19F8 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $120,355.99 | 5,419 | BN15WD1 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $115,555.44 | 3,367 | BK6L288 |
| 0.14% | ALMS | ALUMIS INC | -- | $113,938.86 | 4,049 | BPLQG36 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $112,591.05 | 5,249 | BJ5FZ74 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $107,782.92 | 3,228 | BJ62Z18 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $107,554.44 | 4,102 | BKX9VD3 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $107,300.33 | 2,879 | BK0VHF6 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $101,347.75 | 1,997 | BMFD115 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $101,010.14 | 2,354 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $97,204.00 | 1,520 | BRXB0C0 |
| 0.11% | GRAL | GRAIL INC | -- | $96,124.16 | 1,408 | BSLSSX7 |
| 0.11% | QURE | UNIQURE NV | -- | $95,482.38 | 2,073 | BJFSR88 |
| 0.11% | IRON | DISC MEDICINE INC | -- | $91,644.42 | 1,253 | BMGJZJ8 |
| 0.11% | TARS | TARSUS PHARMACEUTICALS INC | -- | $88,871.28 | 1,412 | BMH5RL1 |
| 0.11% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $88,555.04 | 1,904 | B72ZBG4 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $86,853.05 | 4,657 | BJH9ZN0 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $86,001.60 | 1,558 | BQXJKH2 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $83,340.00 | 8,334 | 2100362 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $82,192.88 | 3,388 | BMVLGP2 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $79,945.92 | 2,052 | BFXC933 |
| 0.10% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $79,910.96 | 2,767 | BMX9K07 |
| 0.09% | PHVS | PHARVARIS NV | -- | $79,188.20 | 2,290 | BMZ2X38 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $78,586.35 | 10,011 | BL53SR3 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $77,442.84 | 4,577 | BYZM6C2 |
| 0.09% | VCEL | VERICEL CORP | -- | $74,387.28 | 1,672 | BSBMN89 |
| 0.09% | MLYS | MINERALYS THERAPEUTICS INC | -- | $73,007.88 | 2,706 | BP9N0G0 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $72,364.50 | 1,950 | BCBVTX1 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $71,426.73 | 4,209 | BFWLC09 |
| 0.08% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,497.78 | 7,179 | BNZB1X8 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $69,106.18 | 1,898 | BKSGZN7 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $68,317.89 | 2,487 | BBC9WC7 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $66,985.60 | 2,768 | BP7KZP7 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $66,814.24 | 2,042 | BJQ05Z6 |
| 0.08% | PGEN | PRECIGEN INC | -- | $66,644.40 | 11,692 | BKM5C84 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $65,482.16 | 3,646 | BPCK358 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,421.90 | 1,570 | BR3T9B6 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $65,017.22 | 1,478 | BQKXDX4 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $64,530.00 | 956 | BDRW1L7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $64,163.82 | 9,422 | BNC1BX1 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $63,981.95 | 2,155 | BQB42F1 |
| 0.08% | ADMA | ADMA BIOLOGICS INC | -- | $63,620.37 | 7,601 | B9NSBM2 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $63,619.44 | 12,072 | BWJDYK1 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $63,547.02 | 2,907 | BN7Q7R7 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $63,135.01 | 17,203 | BM9FJ13 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $62,553.02 | 2,393 | BPCQZY9 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $62,283.00 | 1,950 | BMVNDH9 |
| 0.07% | SRPT | SAREPTA THERAPEUTICS INC | -- | $62,194.17 | 3,461 | B8DPDT7 |
| 0.07% | CMPS | COMPASS PATHWAYS PLC | -- | $61,793.05 | 4,367 | BMC3HS7 |
| 0.07% | ANIP | ANI PHARMACEUTICALS INC | -- | $61,671.10 | 745 | BCDWBX6 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,910.72 | 14,642 | BF0DMK7 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $60,291.84 | 2,243 | BP6C0S2 |
| 0.07% | ABSI | ABSCI CORP | -- | $59,317.62 | 5,118 | BN94K69 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $58,806.40 | 1,598 | BZ7PJQ1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $57,539.70 | 3,798 | BYSS4X4 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $56,340.51 | 5,529 | BK4PZ38 |
| 0.07% | INVA | INNOVIVA INC | -- | $54,912.78 | 2,418 | BDDXF67 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $54,189.44 | 1,816 | BSRK699 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $53,974.80 | 3,102 | BRXYZ57 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,978.50 | 1,525 | BMGTLY5 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $52,612.74 | 2,073 | BQB42H3 |
| 0.06% | HROW | HARROW INC | -- | $51,813.40 | 1,220 | BHNDW86 |
| 0.06% | NVAX | NOVAVAX INC | -- | $50,792.64 | 5,392 | BJDQXG4 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,431.24 | 1,476 | BQNKXX2 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,323.25 | 1,459 | BLCD809 |
| 0.05% | PSNL | PERSONALIS INC | -- | $46,002.20 | 3,433 | BJQ0608 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $45,385.25 | 479 | BNSP8K3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,858.88 | 5,664 | BLR7H87 |
| 0.05% | MNKD | MANNKIND CORP | -- | $43,158.06 | 10,131 | BF081J4 |
| 0.05% | SVRA | SAVARA INC | -- | $41,382.88 | 6,718 | BYXGN81 |
| 0.05% | ARDX | ARDELYX INC | -- | $41,320.20 | 8,102 | BN89V40 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $41,219.46 | 2,759 | BYP80F1 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $41,016.36 | 3,036 | BFYQFJ2 |
| 0.05% | EYPT | EYEPOINT INC | -- | $39,325.00 | 2,750 | BMGS7L1 |
| 0.05% | XNCR | XENCOR INC | -- | $39,123.00 | 2,430 | BGCYWN8 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $38,553.00 | 1,065 | BX7RSN3 |
| 0.05% | ALVO | ALVOTECH SA | -- | $37,759.77 | 10,233 | BPNTJ34 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $36,767.85 | 3,395 | BKVDFF7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,729.57 | 2,017 | BM90J52 |
| 0.04% | WVE | WAVE LIFE SCIENCES LTD | -- | $36,666.91 | 6,311 | BYZG9R0 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $35,941.23 | 2,873 | BMZ4LN0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $35,760.09 | 1,459 | BT9K6D8 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $32,727.30 | 1,290 | B3X26D8 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $32,714.57 | 1,777 | BRJJYT3 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,507.60 | 898 | BGL0JK3 |
| 0.04% | SLDB | SOLID BIOSCIENCES INC | -- | $32,227.74 | 3,226 | BQHN6C7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,955.61 | 2,913 | BYZD465 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,846.25 | 9,125 | BMFJJ97 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,084.80 | 6,476 | BZ0QMB7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,720.00 | 2,000 | BMFX8Y7 |
| 0.04% | ANNX | ANNEXON INC | -- | $30,668.41 | 5,371 | BMVV9R5 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $30,182.88 | 4,837 | BMCWKZ2 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $29,988.63 | 2,709 | BDDVW37 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $29,634.56 | 2,048 | BMFK3H6 |
| 0.03% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $29,180.28 | 1,446 | BNFWZS4 |
| 0.03% | TBPH | THERAVANCE BIOPHARMA INC | -- | $28,730.00 | 1,690 | BMNDK09 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,394.45 | 2,617 | BJLKVS6 |
| 0.03% | GRFS | GRIFOLS SA-ADR | -- | $28,327.08 | 4,001 | B8K7T65 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $27,790.92 | 1,938 | BLFBZ32 |
| 0.03% | GERN | GERON CORP | -- | $26,922.24 | 21,033 | 2370381 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $26,771.25 | 7,139 | BYWVTY5 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $26,676.72 | 8,442 | BBNBTD2 |
| 0.03% | SPRY | ARS PHARMACEUTICALS INC | -- | $26,088.57 | 3,257 | BMCR7V2 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $24,750.90 | 2,403 | BP0TQC5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $24,217.62 | 4,578 | BYV2W40 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $24,069.00 | 3,390 | BP81R42 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,802.30 | 998 | BKLCWZ3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,745.84 | 607 | BQD3J33 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $23,539.36 | 11,317 | BFZNYB7 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $23,217.48 | 1,716 | BQS7491 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $23,017.28 | 1,144 | BS2CR64 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,822.80 | 1,716 | BKLXFX5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,725.58 | 5,398 | B3MZ6K5 |
| 0.03% | OMER | OMEROS CORP | -- | $22,548.21 | 2,371 | B4NB858 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $21,848.49 | 5,921 | BPBJFM7 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $21,666.00 | 690 | BL95N25 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,346.88 | 621 | BPBPCG8 |
| 0.02% | ZLAB | ZAI LAB LTD-ADR | -- | $20,482.00 | 1,078 | BD9GVY0 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,306.10 | 1,695 | BZ0G875 |
| 0.02% | CRMD | CORMEDIX INC | -- | $20,174.50 | 2,570 | BJ0LT31 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $19,459.04 | 6,401 | BFY7DC4 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,757.63 | 1,993 | BSMLR16 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,600.58 | 2,118 | BDZ30Q0 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,537.30 | 1,070 | BPRBTY7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,176.32 | 10,224 | B4N8MH9 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,122.56 | 4,116 | BYVQJ96 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $16,924.08 | 3,624 | BKX9NQ0 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $16,909.20 | 1,540 | BL5B6Z1 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,819.22 | 1,718 | B91XRN2 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $16,629.17 | 5,347 | BK5MWR1 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,354.00 | 520 | BS2F741 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,303.68 | 5,032 | BZ8FPH3 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $15,514.11 | 2,007 | BP2NYN2 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,990.40 | 2,160 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $14,750.16 | 492 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,909.32 | 954 | B9L5200 |
| 0.02% | KMDA | KAMADA LTD | -- | $13,879.94 | 1,891 | B2Q9833 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,551.81 | 1,671 | B7F2TY6 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $12,338.36 | 1,783 | BRCFFK6 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,243.60 | 3,580 | BDFKQ07 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,192.30 | 2,622 | BLN9Z50 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,056.40 | 1,970 | B12W3P6 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,977.32 | 2,573 | BQ6C357 |
| 0.01% | OABI | OMNIAB INC | -- | $11,697.30 | 4,755 | BN13S71 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,776.35 | 767 | BTNMG41 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,573.81 | 2,119 | BMVBZF5 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,521.60 | 6,576 | BFMLGR4 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $10,394.40 | 3,408 | BMXNGZ6 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,325.80 | 6,074 | BN4JN37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,991.12 | 1,759 | BP7L561 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,389.12 | 1,924 | BMF7DT9 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,347.20 | 1,270 | BP81RK8 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $8,561.28 | 2,352 | 2107437 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,478.98 | 1,965 | BPRB2N7 |
| 0.01% | IVVD | INVIVYD INC | -- | $8,425.64 | 9,658 | BM8NHS1 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $7,993.44 | 2,184 | BJDX8Z9 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $7,942.06 | 3,337 | BZC0D70 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $7,871.01 | 3,039 | BYTYP72 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,176.00 | 3,680 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,084.00 | 5,060 | BRK0149 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $6,944.30 | 649 | BM7V485 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,930.00 | 1,980 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,746.10 | 2,985 | B5LL2C2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,474.48 | 1,527 | BKDQKM6 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,447.00 | 1,228 | 2517058 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $6,249.60 | 930 | BKC9SX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $6,248.76 | 2,076 | BLBR8D5 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $5,827.68 | 1,026 | BQV0J03 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $5,741.00 | 6,487 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,725.28 | 3,253 | BNYJR68 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,681.31 | 7,280 | BMYTJP4 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,257.22 | 7,113 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,158.44 | 2,492 | BPTK6Z2 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $4,129.92 | 717 | BTXQTX3 |
| -- | PEPG | PEPGEN INC | -- | $4,087.80 | 2,271 | BMTX3D7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,474.30 | 1,878 | BKTV702 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,802.07 | 3,685 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,266.76 | 7,696 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 39.10% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 32,706,481 | -- | 4,982 | -- |
| 31.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 26,450,103 | -- | 4,029 | -- |
| 27.65% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 23,134,813 | -- | 3,524 | -- |
| 20.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 17,324,850 | -- | 2,639 | -- |
| 19.72% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 16,497,669 | -- | 2,513 | -- |
| 4.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,155,601 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,003,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $31,748,637.67 | 31,748,638 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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