BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,775,349
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/07/2026- NAV
- NAV Change
- Market Price $82.52
- Market Price Change $-3.85
- Trading Volume (M) 15,232
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,775,349
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/07/2026- NAV
- NAV Change
- Market Price $82.52
- Market Price Change $-3.85
- Trading Volume (M) 15,232
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/07/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.91% | GILD | GILEAD SCIENCES INC | -- | $3,769,901.26 | 28,121 | 2369174 |
| 4.67% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,582,325.00 | 8,429 | 2931034 |
| 4.63% | AMGN | AMGEN INC | -- | $3,551,210.19 | 10,791 | 2023607 |
| 3.90% | REGN | REGENERON PHARMACEUTICALS | -- | $2,997,365.70 | 4,227 | 2730190 |
| 2.08% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,596,730.36 | 5,396 | B00FWN1 |
| 1.50% | RVMD | REVOLUTION MEDICINES INC | -- | $1,149,343.15 | 8,065 | BL71K91 |
| 1.49% | BIIB | BIOGEN INC | -- | $1,142,729.98 | 5,971 | 2455965 |
| 1.32% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,014,847.94 | 1,783 | 2430412 |
| 1.20% | INSM | INSMED INC | -- | $921,165.00 | 8,773 | 2614487 |
| 1.18% | ARGX | ARGENX SE - ADR | -- | $909,343.05 | 1,155 | BDVLM39 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $875,287.20 | 17,436 | BMVP7Y0 |
| 1.12% | ILMN | ILLUMINA INC | -- | $863,331.04 | 6,224 | 2613990 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $823,909.52 | 29,134 | BMW4NZ9 |
| 1.06% | VTRS | VIATRIS INC | -- | $814,982.35 | 46,865 | BMWS3X9 |
| 1.03% | INCY | INCYTE CORP | -- | $792,132.54 | 8,102 | 2471950 |
| 1.02% | MRNA | MODERNA INC | -- | $780,183.42 | 16,073 | BGSXTS3 |
| 0.80% | ASND | ASCENDIS PHARMA A/S | -- | $616,580.70 | 2,505 | BWXJHM8 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $611,224.74 | 4,086 | 2623911 |
| 0.74% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $568,534.80 | 2,505 | B4Q5ZN4 |
| 0.70% | SMMT | SUMMIT THERAPEUTICS INC | -- | $541,254.00 | 31,560 | BMTVQS7 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $532,247.95 | 7,891 | BK1KWG8 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $511,234.50 | 6,725 | BDJ0LS6 |
| 0.65% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $499,559.24 | 934 | BD59BS7 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $495,160.05 | 1,155 | BDCBC61 |
| 0.64% | GH | GUARDANT HEALTH INC | -- | $492,391.62 | 5,337 | BFXC911 |
| 0.64% | EXEL | EXELIXIS INC | -- | $488,485.91 | 10,571 | 2576941 |
| 0.60% | AXSM | AXSOME THERAPEUTICS INC | -- | $458,498.04 | 2,082 | BYZR4X4 |
| 0.58% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $444,470.90 | 5,702 | BYQBFJ8 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $431,333.74 | 4,637 | BK6H543 |
| 0.56% | SNY | SANOFI-ADR | -- | $430,072.80 | 9,960 | 2964557 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $423,651.36 | 7,828 | 2437071 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $412,417.00 | 1,301 | BYYWPW6 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $377,939.52 | 1,134 | BQ721R4 |
| 0.49% | CYTK | CYTOKINETICS INC | -- | $372,490.06 | 5,014 | BBBSBJ5 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $353,666.40 | 1,192 | BD6JX35 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $349,752.90 | 7,070 | BSLSJJ0 |
| 0.42% | IBRX | IMMUNITYBIO INC | -- | $324,748.24 | 41,849 | BNSP0B8 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $313,172.76 | 4,804 | 2975098 |
| 0.41% | ABVX | ABIVAX SA-ADR | -- | $311,500.35 | 2,499 | BLC89B2 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $305,152.00 | 2,980 | BMVBZD3 |
| 0.39% | PCVX | VAXCYTE INC | -- | $301,518.36 | 5,857 | BKPVGH6 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $281,056.23 | 3,321 | BMPRZV5 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $267,519.40 | 2,780 | BF2YWG4 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $256,812.30 | 2,598 | BDCBCD8 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $252,796.08 | 2,456 | BJDX8Y8 |
| 0.31% | ALKS | ALKERMES PLC | -- | $240,153.60 | 6,784 | B3P6D26 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $237,771.66 | 3,437 | BRBCSP4 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $233,627.60 | 3,196 | BQBBDY8 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $229,892.32 | 6,608 | BLR6XK8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $227,882.24 | 11,486 | BT18HP9 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $225,572.14 | 8,287 | BJRFSB7 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $217,202.32 | 3,368 | B17VCN9 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,375.03 | 5,203 | BYTQ6X1 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,804.94 | 3,907 | BDHF4K6 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $201,484.80 | 5,088 | BTZRLN8 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $192,953.30 | 4,154 | BFZQ0L8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,861.09 | 4,869 | BLB0YQ9 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $189,616.00 | 3,386 | BRJ3GY4 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $185,354.38 | 4,262 | BDD19F8 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $182,518.11 | 2,231 | BM9HHL5 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $175,698.32 | 12,806 | BFNF1D6 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $170,367.30 | 810 | 2501578 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $163,028.30 | 4,678 | BP8JSP4 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $160,188.30 | 3,755 | BLFGJD5 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $156,498.72 | 6,937 | 2713317 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $155,342.28 | 4,366 | BKY5JZ8 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $146,115.84 | 2,496 | BGKG6G7 |
| 0.17% | VCYT | VERACYTE INC | -- | $131,940.12 | 3,237 | BFTWZY0 |
| 0.17% | ERAS | ERASCA INC | -- | $131,071.20 | 12,603 | BNLYBF3 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $130,506.09 | 4,147 | BK6L288 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $128,717.36 | 5,482 | BP2P6L0 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $127,208.34 | 6,454 | BD2B4V0 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $126,217.90 | 1,970 | BKVF0J2 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $124,222.95 | 3,173 | BQS9486 |
| 0.16% | ALMS | ALUMIS INC | -- | $122,268.96 | 5,146 | BPLQG36 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $122,021.52 | 2,334 | B72ZBG4 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $117,518.00 | 6,700 | BN15WD1 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $110,778.72 | 1,732 | BMH5RL1 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $108,501.12 | 2,484 | BFXC933 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $107,346.96 | 4,788 | BKS3RS7 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $106,459.10 | 1,870 | BRXB0C0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $104,941.62 | 1,554 | BMGJZJ8 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $104,209.04 | 5,044 | BKX9VD3 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $104,195.52 | 2,904 | BL55460 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,769.29 | 3,933 | BJ62Z18 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $100,958.00 | 3,575 | BK0VHF6 |
| 0.13% | GRAL | GRAIL INC | -- | $99,665.28 | 1,584 | BSLSSX7 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $98,137.95 | 3,435 | BMX9K07 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $97,380.93 | 2,417 | BMFD115 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $94,565.70 | 3,222 | BP9N0G0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $94,145.60 | 4,058 | BV2DHY6 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $92,062.23 | 6,267 | BJ5FZ74 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $91,010.25 | 7,275 | BN2R582 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,869.00 | 10,210 | 2100362 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $88,732.80 | 4,266 | B8DPDT7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $85,774.48 | 8,861 | BNZB1X8 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $82,116.65 | 9,695 | B9NSBM2 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $81,937.68 | 5,412 | BFWLC09 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $81,076.80 | 3,048 | BPCQZY9 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $78,737.58 | 1,818 | BQKXDX4 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $77,956.56 | 4,632 | BYSS4X4 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $77,504.13 | 1,941 | BR3T9B6 |
| 0.10% | PHVS | PHARVARIS NV | -- | $77,405.44 | 2,608 | BMZ2X38 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,609.83 | 913 | BCDWBX6 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $76,203.96 | 2,324 | BJQ05Z6 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $75,597.84 | 1,129 | BDRW1L7 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $74,357.16 | 11,148 | BNC1BX1 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,994.10 | 2,355 | BKSGZN7 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $73,759.14 | 3,591 | BN7Q7R7 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $73,591.32 | 591 | BNSP8K3 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $73,312.90 | 5,218 | BJH9ZN0 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,613.71 | 2,067 | BSBMN89 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $71,458.80 | 2,172 | BMVNDH9 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $70,924.26 | 2,621 | BBC9WC7 |
| 0.09% | ARDX | ARDELYX INC | -- | $69,667.38 | 9,981 | BN89V40 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $69,474.42 | 21,246 | BM9FJ13 |
| 0.09% | INVA | INNOVIVA INC | -- | $68,719.20 | 3,014 | BDDXF67 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $68,148.08 | 4,186 | BMVLGP2 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $67,974.40 | 4,472 | BPCK358 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,917.68 | 4,808 | BYZM6C2 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $65,631.52 | 2,384 | BCBVTX1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $63,380.46 | 1,826 | BQXJKH2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $61,510.05 | 3,105 | BP7KZP7 |
| 0.08% | QURE | UNIQURE NV | -- | $61,244.40 | 2,536 | BJFSR88 |
| 0.08% | NVAX | NOVAVAX INC | -- | $61,185.67 | 6,629 | BJDQXG4 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,776.60 | 14,404 | BKM5C84 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $59,549.11 | 2,579 | BQB42F1 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $59,526.40 | 16,768 | BF0DMK7 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,478.80 | 12,340 | BL53SR3 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $59,290.92 | 6,396 | BK4PZ38 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $59,279.83 | 14,783 | BWJDYK1 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $59,243.85 | 3,805 | BRXYZ57 |
| 0.08% | HROW | HARROW INC | -- | $59,004.55 | 1,511 | BHNDW86 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,480.12 | 7,663 | BYZG9R0 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,989.76 | 2,058 | BD06CS0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,626.08 | 1,784 | BLCD809 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,071.26 | 2,526 | BP6C0S2 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $50,814.36 | 1,292 | BX7RSN3 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $50,627.36 | 1,904 | BZ7PJQ1 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $49,870.26 | 1,958 | BSRK699 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $49,338.93 | 3,261 | BMZ4LN0 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $49,051.58 | 3,362 | BYP80F1 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $48,525.70 | 1,682 | BMGTLY5 |
| 0.06% | EYPT | EYEPOINT INC | -- | $45,178.29 | 3,369 | BMGS7L1 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,779.02 | 6,754 | BLR7H87 |
| 0.06% | MNKD | MANNKIND CORP | -- | $44,524.10 | 12,542 | BF081J4 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $44,359.38 | 1,846 | BNFWZS4 |
| 0.06% | SEPN | SEPTERNA INC | -- | $43,667.58 | 1,821 | BQNKXX2 |
| 0.06% | ALVO | ALVOTECH SA | -- | $43,024.00 | 13,445 | BPNTJ34 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $42,760.13 | 2,219 | BQB42H3 |
| 0.06% | SVRA | SAVARA INC | -- | $42,750.60 | 8,285 | BYXGN81 |
| 0.05% | OMER | OMEROS CORP | -- | $42,221.76 | 2,884 | B4NB858 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,001.78 | 4,963 | B8K7T65 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,209.38 | 3,206 | BJLKVS6 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $38,887.80 | 1,645 | B3X26D8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,950.50 | 10,843 | BMFJJ97 |
| 0.05% | GERN | GERON CORP | -- | $37,938.10 | 25,985 | 2370381 |
| 0.05% | XNCR | XENCOR INC | -- | $36,769.97 | 2,987 | BGCYWN8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,225.00 | 4,025 | BMCR7V2 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $36,211.24 | 839 | BL95N25 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $36,057.60 | 3,840 | BMC3HS7 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $36,015.58 | 2,477 | BMFX8Y7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $35,997.66 | 4,086 | BKVDFF7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,416.32 | 2,406 | BM90J52 |
| 0.05% | ABSI | ABSCI CORP | -- | $35,195.75 | 6,121 | BN94K69 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,129.28 | 2,064 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $34,051.80 | 7,828 | BZ0QMB7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $33,842.82 | 1,091 | BGL0JK3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,011.44 | 3,542 | BYZD465 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $32,669.70 | 2,317 | BMFK3H6 |
| 0.04% | ANNX | ANNEXON INC | -- | $32,518.32 | 5,891 | BMVV9R5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,711.68 | 3,276 | BFYQFJ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,509.20 | 2,129 | BQS7491 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,487.94 | 1,767 | BT9K6D8 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,549.06 | 9,729 | BBNBTD2 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,617.91 | 6,623 | B3MZ6K5 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $27,584.00 | 6,896 | BYWVTY5 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $27,572.18 | 1,395 | BD9GVY0 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $27,223.44 | 1,693 | BRJJYT3 |
| 0.03% | ARVN | ARVINAS INC | -- | $26,534.76 | 2,604 | BDZ30Q0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,511.41 | 4,259 | BJQ0608 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,391.52 | 3,206 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,190.00 | 2,290 | BLFBZ32 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $23,848.02 | 4,907 | BYV2W40 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,474.52 | 5,958 | BMCWKZ2 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,280.40 | 1,210 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,183.04 | 2,976 | BP0TQC5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,028.28 | 2,189 | B91XRN2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $22,885.91 | 7,347 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,440.18 | 3,174 | BQHN6C7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,622.50 | 2,325 | BSMLR16 |
| 0.03% | RGNX | REGENXBIO INC | -- | $21,475.62 | 2,061 | BZ0G875 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $21,188.80 | 2,584 | BP81R42 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,997.72 | 4,964 | BYVQJ96 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,765.96 | 9,148 | BFZNYB7 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,604.75 | 2,075 | BKLXFX5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,555.55 | 765 | BPBPCG8 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $20,281.80 | 12,292 | B4N8MH9 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $20,118.78 | 1,129 | BS2CR64 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $19,758.02 | 2,199 | BRCFFK6 |
| 0.03% | NGNE | NEUROGENE INC | -- | $19,662.54 | 629 | BS2F741 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,443.84 | 741 | BQD3J33 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,394.48 | 2,348 | B2Q9833 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,644.80 | 2,710 | BJDX8Z9 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,126.57 | 1,239 | BPRBTY7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,836.38 | 1,182 | B9L5200 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,676.00 | 4,419 | BMXNGZ6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,606.12 | 3,178 | BLN9Z50 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,351.90 | 865 | BTNMG41 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,291.22 | 2,971 | BQ6C357 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,856.82 | 2,638 | BDRJH21 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,748.92 | 604 | B292NQ7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,221.40 | 4,420 | BDFKQ07 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,127.54 | 11,278 | BM8NHS1 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $15,664.00 | 3,916 | BK5MWR1 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,491.84 | 5,096 | BFY7DC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $15,444.63 | 2,417 | B12W3P6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,020.94 | 2,069 | B7F2TY6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,433.60 | 1,240 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,792.68 | 2,916 | 2107437 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,618.98 | 2,609 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,281.45 | 1,911 | BL5B6Z1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $13,197.82 | 6,803 | BN4JN37 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,147.26 | 8,166 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,373.56 | 1,273 | BQV0J03 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,041.22 | 3,974 | BZ8FPH3 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,963.24 | 4,097 | BZC0D70 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,836.56 | 3,972 | BKX9NQ0 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,774.88 | 3,774 | BYTYP72 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $11,229.08 | 3,362 | BDDVW37 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,707.84 | 6,084 | BRK0149 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,686.00 | 1,560 | BP81RK8 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,297.30 | 1,157 | BKC9SX3 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,143.18 | 4,569 | BKRRKY7 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,008.60 | 2,383 | BMF7DT9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,649.32 | 1,263 | BP2NYN2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,504.00 | 2,400 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,484.08 | 3,676 | B5LL2C2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,212.76 | 1,884 | BKDQKM6 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,031.14 | 2,298 | BPRB2N7 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,716.00 | 2,179 | BP7L561 |
| 0.01% | OABI | OMNIAB INC | -- | $8,611.26 | 5,858 | BN13S71 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,485.56 | 7,857 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,799.69 | 7,954 | BNR5QT9 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,485.43 | 8,823 | BNNXX52 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,264.71 | 1,523 | 2517058 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,149.64 | 3,803 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,304.96 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,191.00 | 3,020 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,729.10 | 2,535 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,012.00 | 2,800 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,961.60 | 886 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,697.00 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,237.31 | 9,419 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 39.46% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,291,425 | -- | 5,132 | -- |
| 27.09% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,800,269 | -- | 3,524 | -- |
| 25.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,472,216 | -- | 3,299 | -- |
| 20.29% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,576,592 | -- | 2,639 | -- |
| 16.92% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,991,314 | -- | 2,201 | -- |
| 4.87% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,736,257 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,197,613.53 | 26,197,614 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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