BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,075,321
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/05/2026- NAV
- NAV Change
- Market Price $82.85
- Market Price Change $+0.31
- Trading Volume (M) 7,073
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,075,321
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/05/2026- NAV
- NAV Change
- Market Price $82.85
- Market Price Change $+0.31
- Trading Volume (M) 7,073
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/05/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.87% | GILD | GILEAD SCIENCES INC | -- | $3,753,591.08 | 28,121 | 2369174 |
| 4.64% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,576,930.44 | 8,429 | 2931034 |
| 4.61% | AMGN | AMGEN INC | -- | $3,556,605.69 | 10,791 | 2023607 |
| 3.85% | REGN | REGENERON PHARMACEUTICALS | -- | $2,968,495.29 | 4,227 | 2730190 |
| 2.11% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,624,789.56 | 5,396 | B00FWN1 |
| 1.59% | INSM | INSMED INC | -- | $1,223,307.12 | 8,773 | 2614487 |
| 1.54% | RVMD | REVOLUTION MEDICINES INC | -- | $1,187,248.65 | 8,065 | BL71K91 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,129,295.23 | 5,971 | 2455965 |
| 1.32% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,020,232.60 | 1,783 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $917,878.50 | 1,155 | BDVLM39 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $879,471.84 | 17,436 | BMVP7Y0 |
| 1.12% | ILMN | ILLUMINA INC | -- | $865,571.68 | 6,224 | 2613990 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $825,074.88 | 29,134 | BMW4NZ9 |
| 1.02% | INCY | INCYTE CORP | -- | $789,701.94 | 8,102 | 2471950 |
| 0.97% | MRNA | MODERNA INC | -- | $750,769.83 | 16,073 | BGSXTS3 |
| 0.94% | VTRS | VIATRIS INC | -- | $727,344.80 | 46,865 | BMWS3X9 |
| 0.73% | ASND | ASCENDIS PHARMA A/S | -- | $564,326.40 | 2,505 | BWXJHM8 |
| 0.72% | SMMT | SUMMIT THERAPEUTICS INC | -- | $553,562.40 | 31,560 | BMTVQS7 |
| 0.72% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $551,855.16 | 4,086 | 2623911 |
| 0.70% | BBIO | BRIDGEBIO PHARMA INC | -- | $542,742.98 | 7,891 | BK1KWG8 |
| 0.69% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $531,711.30 | 2,505 | B4Q5ZN4 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $506,056.25 | 6,725 | BDJ0LS6 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $497,019.60 | 1,155 | BDCBC61 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $477,768.24 | 5,337 | BFXC911 |
| 0.61% | EXEL | EXELIXIS INC | -- | $469,563.82 | 10,571 | 2576941 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $469,306.98 | 934 | BD59BS7 |
| 0.60% | AXSM | AXSOME THERAPEUTICS INC | -- | $464,410.92 | 2,082 | BYZR4X4 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $442,833.50 | 4,637 | BK6H543 |
| 0.56% | SNY | SANOFI-ADR | -- | $431,865.60 | 9,960 | 2964557 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $427,250.86 | 5,702 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $416,762.72 | 7,828 | 2437071 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $387,034.49 | 1,301 | BYYWPW6 |
| 0.50% | CYTK | CYTOKINETICS INC | -- | $386,529.26 | 5,014 | BBBSBJ5 |
| 0.50% | TEM | TEMPUS AI INC-CL A | -- | $382,274.90 | 7,070 | BSLSJJ0 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $377,962.20 | 1,134 | BQ721R4 |
| 0.44% | KRYS | KRYSTAL BIOTECH INC | -- | $339,207.44 | 1,192 | BD6JX35 |
| 0.42% | PCVX | VAXCYTE INC | -- | $325,883.48 | 5,857 | BKPVGH6 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $317,215.42 | 41,849 | BNSP0B8 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $316,439.48 | 4,804 | 2975098 |
| 0.40% | ABVX | ABIVAX SA-ADR | -- | $309,326.22 | 2,499 | BLC89B2 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $302,380.60 | 2,980 | BMVBZD3 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $274,679.91 | 3,321 | BMPRZV5 |
| 0.34% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $259,869.36 | 2,456 | BJDX8Y8 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $257,747.58 | 2,598 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $256,621.80 | 2,780 | BF2YWG4 |
| 0.32% | ALKS | ALKERMES PLC | -- | $245,920.00 | 6,784 | B3P6D26 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $244,363.84 | 6,608 | BLR6XK8 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $230,880.48 | 3,437 | BRBCSP4 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $230,710.08 | 8,287 | BJRFSB7 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $226,947.96 | 3,196 | BQBBDY8 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $219,054.72 | 3,368 | B17VCN9 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $217,659.70 | 11,486 | BT18HP9 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,166.91 | 5,203 | BYTQ6X1 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,648.66 | 3,907 | BDHF4K6 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $201,433.92 | 5,088 | BTZRLN8 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $195,798.79 | 4,154 | BFZQ0L8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $195,406.06 | 3,386 | BRJ3GY4 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $193,153.23 | 4,869 | BLB0YQ9 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $188,163.00 | 810 | 2501578 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $185,819.99 | 2,231 | BM9HHL5 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $173,676.50 | 4,262 | BDD19F8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $171,728.46 | 12,806 | BFNF1D6 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $168,224.00 | 3,755 | BLFGJD5 |
| 0.22% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $165,951.66 | 4,366 | BKY5JZ8 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $155,041.95 | 6,937 | 2713317 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $141,523.20 | 2,496 | BGKG6G7 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $139,638.30 | 4,678 | BP8JSP4 |
| 0.18% | ORKA | ORUKA THERAPEUTICS INC | -- | $135,831.50 | 1,970 | BKVF0J2 |
| 0.17% | ALMS | ALUMIS INC | -- | $134,464.98 | 5,146 | BPLQG36 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $132,664.40 | 5,482 | BP2P6L0 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $130,410.30 | 3,173 | BQS9486 |
| 0.16% | ERAS | ERASCA INC | -- | $125,903.97 | 12,603 | BNLYBF3 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $122,109.68 | 6,454 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $119,848.30 | 4,147 | BK6L288 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $118,130.48 | 5,044 | BKX9VD3 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $117,049.00 | 6,700 | BN15WD1 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $114,809.46 | 2,334 | B72ZBG4 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $112,649.28 | 1,732 | BMH5RL1 |
| 0.14% | VCYT | VERACYTE INC | -- | $106,723.89 | 3,237 | BFTWZY0 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $106,103.80 | 1,870 | BRXB0C0 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $105,967.44 | 2,484 | BFXC933 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $105,383.88 | 4,788 | BKS3RS7 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $105,034.86 | 1,554 | BMGJZJ8 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $102,960.00 | 3,575 | BK0VHF6 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $100,498.86 | 2,417 | BMFD115 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $100,246.08 | 2,904 | BL55460 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $99,373.75 | 9,695 | B9NSBM2 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $98,364.33 | 3,933 | BJ62Z18 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $97,931.85 | 3,435 | BMX9K07 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $94,575.00 | 7,275 | BN2R582 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $94,340.16 | 3,222 | BP9N0G0 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $92,956.14 | 4,266 | B8DPDT7 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $92,196.30 | 10,210 | 2100362 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $90,899.20 | 4,058 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $86,808.48 | 5,412 | BFWLC09 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $86,359.26 | 6,267 | BJ5FZ74 |
| 0.11% | GRAL | GRAIL INC | -- | $86,169.60 | 1,584 | BSLSSX7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $86,040.31 | 8,861 | BNZB1X8 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $81,320.64 | 3,048 | BPCQZY9 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,292.16 | 2,608 | BMZ2X38 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $78,217.12 | 1,129 | BDRW1L7 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $77,367.12 | 11,148 | BNC1BX1 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $77,267.19 | 913 | BCDWBX6 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $76,599.04 | 2,324 | BJQ05Z6 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $76,495.88 | 5,218 | BJH9ZN0 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $76,160.70 | 2,355 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $76,086.27 | 2,067 | BSBMN89 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $75,718.92 | 591 | BNSP8K3 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $74,483.46 | 1,818 | BQKXDX4 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $73,695.96 | 2,172 | BMVNDH9 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $73,556.16 | 4,632 | BYSS4X4 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $73,474.96 | 4,472 | BPCK358 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $72,179.10 | 3,591 | BN7Q7R7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $72,129.92 | 2,621 | BBC9WC7 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $71,599.02 | 21,246 | BM9FJ13 |
| 0.09% | ARDX | ARDELYX INC | -- | $71,164.53 | 9,981 | BN89V40 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,487.60 | 4,186 | BMVLGP2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $69,080.19 | 1,941 | BR3T9B6 |
| 0.09% | INVA | INNOVIVA INC | -- | $68,267.10 | 3,014 | BDDXF67 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,736.64 | 16,768 | BF0DMK7 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $64,868.64 | 2,384 | BCBVTX1 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,023.96 | 6,396 | BK4PZ38 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $63,994.48 | 4,808 | BYZM6C2 |
| 0.08% | PGEN | PRECIGEN INC | -- | $62,369.32 | 14,404 | BKM5C84 |
| 0.08% | HROW | HARROW INC | -- | $61,195.50 | 1,511 | BHNDW86 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $60,081.75 | 3,105 | BP7KZP7 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $59,729.64 | 2,579 | BQB42F1 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $59,132.00 | 14,783 | BWJDYK1 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $57,504.40 | 12,340 | BL53SR3 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $55,286.65 | 3,805 | BRXYZ57 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,020.34 | 7,663 | BYZG9R0 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,969.18 | 2,058 | BD06CS0 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $54,049.60 | 1,826 | BQXJKH2 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,753.28 | 2,526 | BP6C0S2 |
| 0.07% | NVAX | NOVAVAX INC | -- | $53,694.90 | 6,629 | BJDQXG4 |
| 0.07% | QURE | UNIQURE NV | -- | $53,661.76 | 2,536 | BJFSR88 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $52,783.40 | 3,362 | BYP80F1 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $52,004.48 | 1,958 | BSRK699 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $51,450.56 | 1,784 | BLCD809 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $50,174.06 | 1,682 | BMGTLY5 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $47,741.04 | 3,261 | BMZ4LN0 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $47,185.36 | 839 | BL95N25 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,057.50 | 13,445 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $46,323.75 | 3,369 | BMGS7L1 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $46,066.44 | 2,219 | BQB42H3 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $45,633.44 | 1,292 | BX7RSN3 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $45,372.32 | 1,904 | BZ7PJQ1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $43,940.73 | 1,821 | BQNKXX2 |
| 0.06% | SVRA | SAVARA INC | -- | $43,496.25 | 8,285 | BYXGN81 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $43,177.94 | 1,846 | BNFWZS4 |
| 0.06% | GERN | GERON CORP | -- | $42,875.25 | 25,985 | 2370381 |
| 0.06% | OMER | OMEROS CORP | -- | $42,596.68 | 2,884 | B4NB858 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,077.42 | 6,754 | BLR7H87 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $41,044.01 | 4,963 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,779.55 | 1,645 | B3X26D8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,379.57 | 3,206 | BJLKVS6 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,103.02 | 4,086 | BKVDFF7 |
| 0.05% | XNCR | XENCOR INC | -- | $38,382.95 | 2,987 | BGCYWN8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,842.07 | 10,843 | BMFJJ97 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,345.75 | 4,025 | BMCR7V2 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,945.64 | 2,406 | BM90J52 |
| 0.05% | MNKD | MANNKIND CORP | -- | $35,870.12 | 12,542 | BF081J4 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $35,788.80 | 3,840 | BMC3HS7 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,495.41 | 2,477 | BMFX8Y7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,530.72 | 2,064 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $34,443.20 | 7,828 | BZ0QMB7 |
| 0.04% | ABSI | ABSCI CORP | -- | $34,338.81 | 6,121 | BN94K69 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,696.52 | 5,891 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,616.91 | 2,129 | BQS7491 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $33,144.58 | 1,091 | BGL0JK3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,905.18 | 3,542 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,941.00 | 3,276 | BFYQFJ2 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,070.97 | 2,317 | BMFK3H6 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,929.41 | 6,623 | B3MZ6K5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,354.48 | 9,729 | BBNBTD2 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,766.00 | 1,210 | BKLCWZ3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $29,473.56 | 1,767 | BT9K6D8 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $29,267.10 | 1,395 | BD9GVY0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $28,135.68 | 6,896 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $27,628.44 | 2,604 | BDZ30Q0 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,275.36 | 1,693 | BRJJYT3 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $24,906.33 | 7,347 | BPBJFM7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,782.38 | 3,206 | BJ0LT31 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $24,570.00 | 1,560 | BP81RK8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,494.91 | 2,189 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,296.90 | 2,290 | BLFBZ32 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $23,923.51 | 1,129 | BS2CR64 |
| 0.03% | PSNL | PERSONALIS INC | -- | $23,680.04 | 4,259 | BJQ0608 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $23,308.25 | 4,907 | BYV2W40 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $22,997.60 | 2,584 | BP81R42 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,938.30 | 5,958 | BMCWKZ2 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,825.92 | 2,976 | BP0TQC5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,460.40 | 765 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $21,900.60 | 3,174 | BQHN6C7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,413.25 | 2,325 | BSMLR16 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,814.69 | 741 | BQD3J33 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,749.52 | 4,964 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,148.25 | 2,075 | BKLXFX5 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,054.88 | 2,199 | BRCFFK6 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $19,851.16 | 9,148 | BFZNYB7 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,421.36 | 12,292 | B4N8MH9 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,277.08 | 2,348 | B2Q9833 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,024.20 | 2,710 | BJDX8Z9 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,002.42 | 2,061 | BZ0G875 |
| 0.02% | NGNE | NEUROGENE INC | -- | $18,203.26 | 629 | BS2F741 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $17,861.63 | 2,417 | B12W3P6 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,836.30 | 865 | BTNMG41 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,829.21 | 1,239 | BPRBTY7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,796.80 | 3,178 | BLN9Z50 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,720.19 | 4,419 | BMXNGZ6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,707.16 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,147.56 | 604 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,115.36 | 1,182 | B9L5200 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,804.06 | 2,638 | BDRJH21 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $16,251.40 | 3,916 | BK5MWR1 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,676.42 | 11,278 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,646.90 | 6,803 | BN4JN37 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,646.80 | 4,420 | BDFKQ07 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,593.76 | 5,096 | BFY7DC4 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,207.15 | 2,069 | B7F2TY6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,594.80 | 1,240 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,932.06 | 2,609 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,644.54 | 1,911 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,530.24 | 2,916 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,392.24 | 8,166 | BFMLGR4 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,680.64 | 3,774 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,331.97 | 4,097 | BZC0D70 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,080.96 | 3,974 | BZ8FPH3 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,796.84 | 3,972 | BKX9NQ0 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $11,546.11 | 1,273 | BQV0J03 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,057.12 | 2,383 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,890.36 | 6,084 | BRK0149 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,874.22 | 4,569 | BKRRKY7 |
| 0.01% | CDXS | CODEXIS INC | -- | $10,109.00 | 3,676 | B5LL2C2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,750.36 | 1,263 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,730.37 | 1,157 | BKC9SX3 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $9,648.94 | 3,362 | BDDVW37 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,360.00 | 2,400 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,231.60 | 1,884 | BKDQKM6 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,214.98 | 2,298 | BPRB2N7 |
| 0.01% | OABI | OMNIAB INC | -- | $8,201.20 | 5,858 | BN13S71 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,149.46 | 2,179 | BP7L561 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,858.68 | 1,523 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,646.18 | 7,954 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,339.79 | 3,803 | BNYJR68 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,086.23 | 7,857 | BMYTJP4 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,655.19 | 8,823 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,652.66 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,251.40 | 3,020 | BPTK6Z2 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,404.00 | 2,800 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,846.42 | 886 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,639.05 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,509.97 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,164.78 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.16% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 27,098,405 | -- | 4,585 | -- |
| 30.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 23,209,473 | -- | 3,927 | -- |
| 27.02% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,827,651 | -- | 3,524 | -- |
| 20.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,597,097 | -- | 2,639 | -- |
| 16.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,008,416 | -- | 2,201 | -- |
| 4.85% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,741,176 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,430,905.70 | 26,430,906 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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