BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,744,882
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/22/2026- NAV
- NAV Change
- Market Price $87.03
- Market Price Change $+0.14
- Trading Volume (M) 15,247
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,744,882
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/22/2026- NAV
- NAV Change
- Market Price $87.03
- Market Price Change $+0.14
- Trading Volume (M) 15,247
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/22/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.64% | GILD | GILEAD SCIENCES INC | -- | $3,799,743.90 | 28,591 | 2369174 |
| 4.64% | AMGN | AMGEN INC | -- | $3,795,088.32 | 10,971 | 2023607 |
| 4.58% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,750,831.90 | 8,570 | 2931034 |
| 3.92% | REGN | REGENERON PHARMACEUTICALS | -- | $3,208,800.84 | 4,298 | 2730190 |
| 2.08% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,703,841.88 | 5,486 | B00FWN1 |
| 1.57% | INSM | INSMED INC | -- | $1,288,761.60 | 8,920 | 2614487 |
| 1.42% | RVMD | REVOLUTION MEDICINES INC | -- | $1,160,300.00 | 8,200 | BL71K91 |
| 1.41% | BIIB | BIOGEN INC | -- | $1,153,914.97 | 6,071 | 2455965 |
| 1.27% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,041,187.77 | 1,813 | 2430412 |
| 1.14% | ARGX | ARGENX SE - ADR | -- | $931,240.28 | 1,174 | BDVLM39 |
| 1.11% | MRNA | MODERNA INC | -- | $908,615.20 | 16,342 | BGSXTS3 |
| 1.08% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $881,436.16 | 17,728 | BMVP7Y0 |
| 1.05% | ROIV | ROIVANT SCIENCES LTD | -- | $863,452.15 | 29,621 | BMW4NZ9 |
| 1.01% | ILMN | ILLUMINA INC | -- | $825,804.00 | 6,328 | 2613990 |
| 0.97% | INCY | INCYTE CORP | -- | $796,847.38 | 8,237 | 2471950 |
| 0.96% | SMMT | SUMMIT THERAPEUTICS INC | -- | $788,723.04 | 32,088 | BMTVQS7 |
| 0.85% | VTRS | VIATRIS INC | -- | $691,863.48 | 47,649 | BMWS3X9 |
| 0.73% | BBIO | BRIDGEBIO PHARMA INC | -- | $597,232.12 | 8,023 | BK1KWG8 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $596,932.04 | 1,174 | BDCBC61 |
| 0.72% | -- | ASCENDIS PHARMA A/S | -- | $588,484.35 | 2,547 | -- |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $544,921.72 | 4,154 | 2623911 |
| 0.63% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $515,512.80 | 2,547 | B4Q5ZN4 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $512,049.00 | 4,715 | BK6H543 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $511,612.71 | 6,837 | BDJ0LS6 |
| 0.62% | EXEL | EXELIXIS INC | -- | $503,543.80 | 10,748 | 2576941 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $502,683.00 | 950 | BD59BS7 |
| 0.59% | GH | GUARDANT HEALTH INC | -- | $485,952.56 | 5,426 | BFXC911 |
| 0.58% | SNY | SANOFI-ADR | -- | $474,956.30 | 10,127 | 2964557 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $430,979.85 | 7,959 | 2437071 |
| 0.52% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $428,514.24 | 5,797 | BYQBFJ8 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $413,318.43 | 1,323 | BYYWPW6 |
| 0.49% | TEM | TEMPUS AI INC-CL A | -- | $399,005.88 | 7,188 | BSLSJJ0 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $394,651.14 | 2,117 | BYZR4X4 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $388,895.37 | 1,153 | BQ721R4 |
| 0.44% | PCVX | VAXCYTE INC | -- | $362,123.55 | 5,955 | BKPVGH6 |
| 0.42% | IBRX | IMMUNITYBIO INC | -- | $343,370.43 | 42,549 | BNSP0B8 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $337,742.50 | 5,098 | BBBSBJ5 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $334,439.28 | 1,212 | BD6JX35 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $334,065.60 | 4,884 | 2975098 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $329,815.50 | 3,030 | BMVBZD3 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $299,776.29 | 3,377 | BMPRZV5 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $294,730.59 | 2,541 | BLC89B2 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $278,757.55 | 2,641 | BDCBCD8 |
| 0.34% | ERAS | ERASCA INC | -- | $277,423.10 | 12,814 | BNLYBF3 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $248,482.74 | 8,426 | BJRFSB7 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $244,468.02 | 6,718 | BLR6XK8 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $244,160.72 | 3,494 | BRBCSP4 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $242,590.40 | 3,424 | B17VCN9 |
| 0.29% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $240,704.55 | 2,826 | BF2YWG4 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $239,399.00 | 11,678 | BT18HP9 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $237,177.00 | 3,249 | BQBBDY8 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $235,492.07 | 2,497 | BJDX8Y8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $232,704.78 | 6,897 | B3P6D26 |
| 0.28% | TERN | TERNS PHARMACEUTICALS INC | -- | $232,548.84 | 4,401 | BMDJ0C9 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $224,100.24 | 3,972 | BDHF4K6 |
| 0.26% | APLS | APELLIS PHARMACEUTICALS INC | -- | $216,308.10 | 5,290 | BYTQ6X1 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $205,662.24 | 2,268 | BM9HHL5 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $199,874.59 | 4,223 | BFZQ0L8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $195,376.50 | 4,950 | BLB0YQ9 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $195,045.95 | 3,443 | BRJ3GY4 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $186,940.88 | 824 | 2501578 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $172,726.47 | 5,173 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $169,420.30 | 4,333 | BDD19F8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $166,916.40 | 13,020 | BFNF1D6 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $160,401.60 | 2,538 | BGKG6G7 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $156,858.72 | 7,053 | 2713317 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $153,063.62 | 3,818 | BLFGJD5 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $151,906.64 | 4,756 | BP8JSP4 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $150,163.56 | 5,574 | BP2P6L0 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $150,009.00 | 3,226 | BQS9486 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $142,802.63 | 4,439 | BKY5JZ8 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $139,569.04 | 2,003 | BKVF0J2 |
| 0.17% | ALMS | ALUMIS INC | -- | $135,456.48 | 5,232 | BPLQG36 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $133,992.04 | 6,812 | BN15WD1 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $133,605.04 | 4,216 | BK6L288 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $132,880.50 | 6,562 | BD2B4V0 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $122,124.47 | 7,397 | BN2R582 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $121,790.00 | 5,128 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $119,338.17 | 2,373 | B72ZBG4 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $118,917.31 | 2,953 | BL55460 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $115,120.45 | 3,635 | BK0VHF6 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $114,149.94 | 2,526 | BFXC933 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $111,788.28 | 1,761 | BMH5RL1 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $111,136.44 | 4,868 | BKS3RS7 |
| 0.14% | VCYT | VERACYTE INC | -- | $110,939.61 | 3,291 | BFTWZY0 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $110,141.80 | 1,580 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $109,189.08 | 2,457 | BMFD115 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $107,934.15 | 9,857 | B9NSBM2 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $98,415.39 | 3,999 | BJ62Z18 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $95,228.08 | 4,126 | BV2DHY6 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $94,774.68 | 3,276 | BP9N0G0 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $93,532.81 | 10,381 | 2100362 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $90,547.56 | 3,492 | BMX9K07 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $90,482.40 | 6,372 | BJ5FZ74 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $90,342.84 | 5,502 | BFWLC09 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $89,515.68 | 4,337 | B8DPDT7 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $88,414.47 | 3,099 | BPCQZY9 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $87,026.94 | 9,009 | BNZB1X8 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $84,831.70 | 2,363 | BJQ05Z6 |
| 0.10% | GRAL | GRAIL INC | -- | $84,738.60 | 1,611 | BSLSSX7 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $82,468.80 | 2,208 | BMVNDH9 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $81,819.04 | 1,901 | BRXB0C0 |
| 0.10% | NTLA | INTELLIA THERAPEUTICS INC | -- | $80,994.16 | 4,888 | BYZM6C2 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $80,614.08 | 3,651 | BN7Q7R7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $80,571.73 | 21,601 | BM9FJ13 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $79,833.60 | 1,848 | BQKXDX4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $79,666.08 | 2,652 | BMZ2X38 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $79,663.44 | 4,547 | BPCK358 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $78,514.00 | 5,305 | BJH9ZN0 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $76,536.18 | 2,394 | BKSGZN7 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $76,164.48 | 11,334 | BNC1BX1 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,369.92 | 928 | BCDWBX6 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $73,793.85 | 2,665 | BBC9WC7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $72,566.94 | 1,973 | BR3T9B6 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,245.74 | 2,102 | BSBMN89 |
| 0.09% | INVA | INNOVIVA INC | -- | $72,004.00 | 3,064 | BDDXF67 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $70,791.30 | 15,030 | BWJDYK1 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $70,777.28 | 4,256 | BMVLGP2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $69,387.01 | 6,503 | BK4PZ38 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $69,169.09 | 601 | BNSP8K3 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $66,233.86 | 3,157 | BP7KZP7 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $64,769.28 | 2,424 | BCBVTX1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $62,358.06 | 1,857 | BQXJKH2 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $61,957.86 | 2,622 | BQB42F1 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $61,475.40 | 1,148 | BDRW1L7 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $61,311.18 | 4,709 | BYSS4X4 |
| 0.07% | ARDX | ARDELYX INC | -- | $61,090.96 | 10,148 | BN89V40 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $61,011.30 | 3,418 | BYP80F1 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,179.44 | 17,048 | BF0DMK7 |
| 0.07% | HROW | HARROW INC | -- | $60,119.04 | 1,536 | BHNDW86 |
| 0.07% | PGEN | PRECIGEN INC | -- | $57,994.20 | 14,645 | BKM5C84 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $57,497.58 | 7,791 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $56,953.00 | 6,740 | BJDQXG4 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,383.72 | 1,814 | BLCD809 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $53,851.84 | 3,316 | BMZ4LN0 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,830.45 | 1,710 | BMGTLY5 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $52,761.50 | 1,991 | BSRK699 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,187.68 | 12,546 | BL53SR3 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $50,452.16 | 1,936 | BZ7PJQ1 |
| 0.06% | EYPT | EYEPOINT INC | -- | $48,772.00 | 3,425 | BMGS7L1 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $48,663.60 | 2,568 | BP6C0S2 |
| 0.06% | SEPN | SEPTERNA INC | -- | $47,866.86 | 1,851 | BQNKXX2 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,845.00 | 13,670 | BPNTJ34 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $46,036.41 | 853 | BL95N25 |
| 0.06% | QURE | UNIQURE NV | -- | $45,836.84 | 2,578 | BJFSR88 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $45,277.92 | 2,256 | BQB42H3 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $44,738.58 | 4,154 | BKVDFF7 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $43,440.84 | 1,314 | BX7RSN3 |
| 0.05% | SVRA | SAVARA INC | -- | $43,294.22 | 8,423 | BYXGN81 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $42,335.94 | 5,046 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,624.24 | 1,673 | B3X26D8 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,476.68 | 6,867 | BLR7H87 |
| 0.05% | GERN | GERON CORP | -- | $40,949.45 | 26,419 | 2370381 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $40,919.52 | 2,092 | BD06CS0 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $40,678.56 | 11,024 | BMFJJ97 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,624.50 | 3,869 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,398.23 | 1,877 | BNFWZS4 |
| 0.05% | OMER | OMEROS CORP | -- | $39,200.84 | 2,932 | B4NB858 |
| 0.05% | XNCR | XENCOR INC | -- | $39,025.45 | 3,037 | BGCYWN8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $38,752.02 | 2,518 | BMFX8Y7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $38,239.80 | 3,260 | BJLKVS6 |
| 0.05% | ANNX | ANNEXON INC | -- | $37,491.14 | 5,989 | BMVV9R5 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $35,258.37 | 7,959 | BZ0QMB7 |
| 0.04% | MNKD | MANNKIND CORP | -- | $34,940.48 | 12,752 | BF081J4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,763.86 | 2,098 | BMNDK09 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,372.80 | 4,092 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,317.53 | 3,601 | BYZD465 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $34,160.00 | 3,904 | BMC3HS7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,077.10 | 2,165 | BQS7491 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,852.64 | 2,446 | BM90J52 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $33,409.93 | 3,331 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,992.92 | 1,797 | BT9K6D8 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,429.66 | 1,418 | BD9GVY0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,320.71 | 7,011 | BYWVTY5 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,499.72 | 2,356 | BMFK3H6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,873.00 | 1,230 | BKLCWZ3 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,581.20 | 7,470 | BPBJFM7 |
| 0.03% | ARVN | ARVINAS INC | -- | $28,148.24 | 2,648 | BDZ30Q0 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $28,148.12 | 6,734 | B3MZ6K5 |
| 0.03% | PSNL | PERSONALIS INC | -- | $27,322.30 | 4,330 | BJQ0608 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,106.80 | 3,227 | BQHN6C7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,365.72 | 1,721 | BRJJYT3 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $26,183.49 | 1,109 | BGL0JK3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,420.72 | 2,328 | BLFBZ32 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,417.40 | 3,260 | BJ0LT31 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $24,183.72 | 2,364 | BSMLR16 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,862.72 | 2,226 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,943.91 | 753 | BQD3J33 |
| 0.03% | ABSI | ABSCI CORP | -- | $22,900.64 | 6,223 | BN94K69 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,354.02 | 6,058 | BMCWKZ2 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,229.39 | 9,301 | BFZNYB7 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,210.84 | 3,026 | BP0TQC5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,173.00 | 778 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,901.71 | 4,989 | BYV2W40 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,781.62 | 879 | BTNMG41 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $21,662.76 | 1,148 | BS2CR64 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $21,555.04 | 2,236 | BRCFFK6 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $21,371.58 | 12,498 | B4N8MH9 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $21,351.25 | 2,755 | BJDX8Z9 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,945.05 | 5,047 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,697.30 | 1,586 | BP81RK8 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,678.00 | 2,110 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $20,488.08 | 4,493 | BMXNGZ6 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,955.32 | 2,387 | B2Q9833 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,676.23 | 2,627 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,567.30 | 2,095 | BZ0G875 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,487.24 | 9,892 | BBNBTD2 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $19,122.93 | 3,021 | BQ6C357 |
| 0.02% | IVVD | INVIVYD INC | -- | $18,347.20 | 11,467 | BM8NHS1 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $18,125.91 | 3,231 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,978.07 | 5,181 | BFY7DC4 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,891.96 | 614 | B292NQ7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,452.80 | 640 | BS2F741 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,077.20 | 4,494 | BDFKQ07 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,781.31 | 2,457 | B12W3P6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,575.58 | 1,202 | B9L5200 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,329.60 | 1,260 | BPRBTY7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,978.27 | 6,917 | BN4JN37 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,632.72 | 2,104 | B7F2TY6 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,626.17 | 2,653 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $15,485.71 | 1,943 | BL5B6Z1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,425.84 | 1,261 | BM7V485 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,919.58 | 2,682 | BDRJH21 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $13,851.57 | 3,837 | BYTYP72 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $13,453.20 | 4,040 | BZ8FPH3 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,372.15 | 2,965 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,284.80 | 8,303 | BFMLGR4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,059.97 | 2,423 | BMF7DT9 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,927.06 | 1,294 | BQV0J03 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,744.90 | 4,165 | BZC0D70 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,622.94 | 3,982 | BK5MWR1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,396.66 | 4,038 | BKX9NQ0 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,984.10 | 4,645 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,134.80 | 6,186 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,137.12 | 1,176 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,101.60 | 2,440 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,834.56 | 2,336 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,560.84 | 1,916 | BKDQKM6 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,230.39 | 3,737 | B5LL2C2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $9,126.12 | 3,867 | BNYJR68 |
| 0.01% | OABI | OMNIAB INC | -- | $8,934.00 | 5,956 | BN13S71 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,572.22 | 8,087 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,096.04 | 1,548 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,063.52 | 1,284 | BP2NYN2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,895.95 | 2,357 | BKTV702 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $7,758.86 | 3,418 | BDDVW37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,132.30 | 2,215 | BP7L561 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,001.88 | 3,071 | BPTK6Z2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,603.55 | 8,971 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,630.74 | 7,988 | BMYTJP4 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,982.53 | 901 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,844.76 | 2,577 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,726.02 | 2,847 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,835.15 | 4,037 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,734.07 | 9,577 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 38.00% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,107,537 | -- | 5,140 | -- |
| 29.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,002,430 | -- | 3,966 | -- |
| 27.37% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,404,689 | -- | 3,702 | -- |
| 19.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,971,360 | -- | 2,639 | -- |
| 16.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,320,562 | -- | 2,201 | -- |
| 4.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,830,948 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,908,001.17 | 28,908,001 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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