BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,845,017
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/26/2026- NAV
- NAV Change
- Market Price $82.52
- Market Price Change $+0.56
- Trading Volume (M) 981
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,845,017
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/26/2026- NAV
- NAV Change
- Market Price $82.52
- Market Price Change $+0.56
- Trading Volume (M) 981
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/26/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.75% | GILD | GILEAD SCIENCES INC | -- | $3,415,731.66 | 25,542 | 2369174 |
| 4.65% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,337,916.01 | 7,657 | 2931034 |
| 4.58% | AMGN | AMGEN INC | -- | $3,293,219.82 | 9,803 | 2023607 |
| 3.39% | REGN | REGENERON PHARMACEUTICALS | -- | $2,436,940.80 | 3,840 | 2730190 |
| 2.02% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,449,132.00 | 4,904 | B00FWN1 |
| 1.58% | RVMD | REVOLUTION MEDICINES INC | -- | $1,134,724.14 | 7,326 | BL71K91 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,047,459.00 | 5,425 | 2455965 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $937,056.60 | 1,620 | 2430412 |
| 1.21% | INSM | INSMED INC | -- | $867,476.16 | 7,968 | 2614487 |
| 1.19% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $852,980.82 | 15,837 | BMVP7Y0 |
| 1.18% | ARGX | ARGENX SE - ADR | -- | $848,851.50 | 1,050 | BDVLM39 |
| 1.14% | ILMN | ILLUMINA INC | -- | $820,956.93 | 5,653 | 2613990 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $784,935.90 | 26,460 | BMW4NZ9 |
| 0.99% | INCY | INCYTE CORP | -- | $714,558.90 | 7,359 | 2471950 |
| 0.96% | VTRS | VIATRIS INC | -- | $692,106.90 | 42,565 | BMWS3X9 |
| 0.96% | MRNA | MODERNA INC | -- | $686,638.00 | 14,600 | BGSXTS3 |
| 0.81% | GH | GUARDANT HEALTH INC | -- | $581,272.50 | 4,850 | BFXC911 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $578,069.76 | 3,712 | 2623911 |
| 0.76% | ASND | ASCENDIS PHARMA A/S | -- | $545,443.40 | 2,276 | BWXJHM8 |
| 0.75% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $540,107.75 | 2,275 | B4Q5ZN4 |
| 0.68% | SMMT | SUMMIT THERAPEUTICS INC | -- | $487,288.00 | 28,664 | BMTVQS7 |
| 0.68% | BBIO | BRIDGEBIO PHARMA INC | -- | $485,420.91 | 7,167 | BK1KWG8 |
| 0.67% | EXEL | EXELIXIS INC | -- | $479,808.00 | 9,600 | 2576941 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $464,711.63 | 6,109 | BDJ0LS6 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $450,994.61 | 1,051 | BDCBC61 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $444,065.16 | 847 | BD59BS7 |
| 0.62% | AXSM | AXSOME THERAPEUTICS INC | -- | $442,638.00 | 1,890 | BYZR4X4 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $407,405.04 | 5,178 | BYQBFJ8 |
| 0.56% | SNY | SANOFI-ADR | -- | $399,425.05 | 9,047 | 2964557 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $388,649.25 | 4,213 | BK6H543 |
| 0.52% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $375,976.80 | 7,110 | 2437071 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $360,767.40 | 1,029 | BQ721R4 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $357,181.64 | 1,181 | BYYWPW6 |
| 0.48% | CYTK | CYTOKINETICS INC | -- | $347,348.37 | 4,553 | BBBSBJ5 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $326,894.40 | 1,080 | BD6JX35 |
| 0.42% | IBRX | IMMUNITYBIO INC | -- | $301,023.36 | 38,008 | BNSP0B8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $299,894.08 | 4,364 | 2975098 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $299,743.84 | 6,424 | BSLSJJ0 |
| 0.40% | ABVX | ABIVAX SA-ADR | -- | $287,077.11 | 2,271 | BLC89B2 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $283,889.75 | 2,705 | BMVBZD3 |
| 0.37% | PCVX | VAXCYTE INC | -- | $266,635.31 | 5,321 | BKPVGH6 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $254,503.09 | 7,523 | BJRFSB7 |
| 0.34% | KYMR | KYMERA THERAPEUTICS INC | -- | $243,683.09 | 3,017 | BMPRZV5 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $236,052.78 | 2,361 | BDCBCD8 |
| 0.32% | ALKS | ALKERMES PLC | -- | $230,188.05 | 6,163 | B3P6D26 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $226,885.32 | 2,526 | BF2YWG4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $220,645.90 | 2,231 | BJDX8Y8 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $213,953.25 | 2,905 | BQBBDY8 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $207,144.30 | 3,062 | B17VCN9 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $203,707.88 | 6,002 | BLR6XK8 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $194,347.23 | 3,773 | BFZQ0L8 |
| 0.27% | CGON | CG ONCOLOGY INC | -- | $193,282.47 | 3,123 | BRBCSP4 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $183,144.50 | 3,550 | BDHF4K6 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,946.94 | 4,423 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $174,833.44 | 4,624 | BTZRLN8 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $173,202.88 | 736 | 2501578 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $167,938.68 | 2,028 | BM9HHL5 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $165,934.52 | 3,074 | BRJ3GY4 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $161,889.12 | 10,431 | BT18HP9 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $153,539.72 | 4,252 | BP8JSP4 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $150,984.61 | 3,409 | BLFGJD5 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $148,773.28 | 11,632 | BFNF1D6 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $146,995.42 | 2,266 | BGKG6G7 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $142,412.16 | 3,872 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $134,001.78 | 6,303 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $133,098.96 | 3,966 | BKY5JZ8 |
| 0.18% | ERAS | ERASCA INC | -- | $131,606.00 | 11,444 | BNLYBF3 |
| 0.18% | VCYT | VERACYTE INC | -- | $129,888.98 | 2,938 | BFTWZY0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $113,990.40 | 2,880 | BQS9486 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $113,624.94 | 5,863 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $112,218.93 | 3,767 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $110,479.05 | 6,087 | BN15WD1 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $107,121.62 | 4,351 | BKS3RS7 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $105,658.34 | 1,789 | BKVF0J2 |
| 0.15% | ALMS | ALUMIS INC | -- | $104,370.42 | 4,674 | BPLQG36 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $101,272.40 | 2,120 | B72ZBG4 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $99,759.12 | 4,978 | BP2P6L0 |
| 0.14% | GRAL | GRAIL INC | -- | $99,233.44 | 1,439 | BSLSSX7 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $96,831.57 | 4,587 | BKX9VD3 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $96,204.68 | 1,573 | BMH5RL1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $96,117.32 | 1,411 | BMGJZJ8 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $95,270.10 | 3,246 | BK0VHF6 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $93,607.02 | 6,606 | BN2R582 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $93,395.88 | 2,196 | BMFD115 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $92,192.66 | 3,122 | BMX9K07 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $90,520.24 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $89,756.28 | 1,698 | BRXB0C0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $87,720.75 | 2,925 | BP9N0G0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,312.80 | 3,685 | BV2DHY6 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $82,632.94 | 3,571 | BJ62Z18 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $81,180.00 | 2,255 | BFXC933 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $80,427.96 | 5,692 | BJ5FZ74 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $78,525.37 | 9,271 | 2100362 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $76,856.34 | 4,209 | BYSS4X4 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $74,643.66 | 4,914 | BFWLC09 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $71,760.75 | 8,805 | B9NSBM2 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $70,794.88 | 1,651 | BQKXDX4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $70,725.96 | 2,367 | BMZ2X38 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $70,256.40 | 2,766 | BPCQZY9 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $70,048.44 | 1,764 | BR3T9B6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $68,189.96 | 4,742 | BJH9ZN0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,570.30 | 830 | BCDWBX6 |
| 0.09% | OCUL | OCULAR THERAPEUTIX INC | -- | $66,726.21 | 8,049 | BNZB1X8 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $66,306.66 | 1,974 | BMVNDH9 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $66,078.76 | 3,802 | BMVLGP2 |
| 0.09% | VCEL | VERICEL CORP | -- | $65,568.75 | 1,875 | BSBMN89 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $65,504.33 | 2,111 | BJQ05Z6 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $64,893.90 | 3,261 | BN7Q7R7 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $64,596.25 | 3,875 | B8DPDT7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $64,392.60 | 2,140 | BKSGZN7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $63,971.31 | 2,379 | BBC9WC7 |
| 0.09% | NVAX | NOVAVAX INC | -- | $63,000.58 | 6,023 | BJDQXG4 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $62,451.20 | 15,232 | BF0DMK7 |
| 0.09% | INVA | INNOVIVA INC | -- | $62,143.20 | 2,740 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $61,362.78 | 2,166 | BCBVTX1 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,295.61 | 11,209 | BL53SR3 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $59,098.71 | 1,023 | BDRW1L7 |
| 0.08% | QURE | UNIQURE NV | -- | $57,970.75 | 2,305 | BJFSR88 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $57,610.41 | 13,429 | BWJDYK1 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $57,378.45 | 537 | BNSP8K3 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $57,312.09 | 19,297 | BM9FJ13 |
| 0.08% | ARDX | ARDELYX INC | -- | $56,662.50 | 9,066 | BN89V40 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,615.52 | 10,128 | BNC1BX1 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $55,527.12 | 4,059 | BPCK358 |
| 0.08% | PGEN | PRECIGEN INC | -- | $55,459.20 | 13,080 | BKM5C84 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $55,093.09 | 4,369 | BYZM6C2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,497.80 | 5,810 | BK4PZ38 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,105.60 | 2,818 | BP7KZP7 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,106.10 | 2,294 | BP6C0S2 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,641.50 | 1,658 | BQXJKH2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $51,499.14 | 2,343 | BQB42F1 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $50,965.80 | 1,730 | BZ7PJQ1 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,778.77 | 1,657 | BQNKXX2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,134.70 | 1,870 | BD06CS0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $47,673.61 | 1,621 | BLCD809 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $46,850.30 | 1,778 | BSRK699 |
| 0.07% | HROW | HARROW INC | -- | $46,812.90 | 1,370 | BHNDW86 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $45,675.10 | 3,455 | BRXYZ57 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $44,404.80 | 6,960 | BYZG9R0 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $42,664.38 | 1,527 | BMGTLY5 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $42,628.58 | 3,487 | BMC3HS7 |
| 0.06% | ALVO | ALVOTECH SA | -- | $41,758.20 | 12,210 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $40,877.70 | 3,062 | BMGS7L1 |
| 0.06% | MNKD | MANNKIND CORP | -- | $40,203.17 | 11,389 | BF081J4 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $40,135.10 | 2,962 | BMZ4LN0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,590.16 | 1,172 | BX7RSN3 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $39,182.82 | 3,054 | BYP80F1 |
| 0.05% | SVRA | SAVARA INC | -- | $38,673.36 | 7,524 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $38,398.84 | 6,134 | BLR7H87 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $37,141.59 | 1,983 | BQB42H3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $36,418.20 | 1,495 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $36,125.10 | 4,510 | B8K7T65 |
| 0.05% | PSNL | PERSONALIS INC | -- | $34,588.86 | 3,869 | BJQ0608 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,780.10 | 2,185 | BM90J52 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $33,499.38 | 3,218 | BYZD465 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,990.40 | 7,110 | BZ0QMB7 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $32,414.40 | 2,251 | BMFX8Y7 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $32,323.20 | 2,912 | BJLKVS6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,691.94 | 3,711 | BKVDFF7 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $31,544.37 | 1,677 | BNFWZS4 |
| 0.04% | XNCR | XENCOR INC | -- | $31,528.93 | 2,711 | BGCYWN8 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,039.68 | 992 | BGL0JK3 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,768.75 | 1,875 | BMNDK09 |
| 0.04% | OMER | OMEROS CORP | -- | $30,546.30 | 2,622 | B4NB858 |
| 0.04% | GERN | GERON CORP | -- | $30,210.56 | 23,602 | 2370381 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,039.45 | 9,849 | BMFJJ97 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $29,869.52 | 3,656 | BMCR7V2 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,526.48 | 5,349 | BMVV9R5 |
| 0.04% | ABSI | ABSCI CORP | -- | $29,362.08 | 5,561 | BN94K69 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,816.60 | 1,934 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,560.00 | 2,975 | BFYQFJ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,571.44 | 8,837 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $25,984.80 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,697.84 | 763 | BL95N25 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,073.97 | 2,911 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,997.00 | 2,105 | BMFK3H6 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,695.80 | 5,410 | BMCWKZ2 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,509.20 | 6,028 | B3MZ6K5 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $23,413.05 | 1,269 | BD9GVY0 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $23,117.85 | 6,265 | BYWVTY5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,659.00 | 1,100 | BKLCWZ3 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $21,657.60 | 1,536 | BRJJYT3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,520.65 | 2,707 | BP0TQC5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $21,496.56 | 2,083 | BLFBZ32 |
| 0.03% | ARVN | ARVINAS INC | -- | $21,077.96 | 2,363 | BDZ30Q0 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,783.07 | 693 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,110.09 | 4,459 | BYV2W40 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,009.34 | 1,989 | B91XRN2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,818.81 | 6,673 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $19,814.40 | 2,880 | BQHN6C7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,602.24 | 672 | BQD3J33 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,404.88 | 4,511 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,184.32 | 2,112 | BSMLR16 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,875.89 | 2,349 | BP81R42 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,612.96 | 8,308 | BFZNYB7 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,447.27 | 1,023 | BS2CR64 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,965.30 | 2,134 | B2Q9833 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,656.64 | 2,464 | BJDX8Z9 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,418.35 | 1,885 | BKLXFX5 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,395.37 | 1,997 | BRCFFK6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,474.10 | 571 | BS2F741 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,398.80 | 1,124 | BPRBTY7 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,163.16 | 548 | B292NQ7 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,981.25 | 2,397 | BDRJH21 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,504.16 | 1,072 | B9L5200 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,065.38 | 11,163 | B4N8MH9 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $14,043.80 | 3,053 | BDDVW37 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,928.58 | 4,014 | BMXNGZ6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,862.58 | 2,697 | BQ6C357 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,660.33 | 1,879 | B7F2TY6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,596.92 | 2,186 | B12W3P6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,571.10 | 5,322 | BN13S71 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,568.83 | 4,631 | BFY7DC4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,232.04 | 3,557 | BK5MWR1 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $13,087.17 | 2,889 | BLN9Z50 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $12,883.19 | 787 | BTNMG41 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,633.75 | 1,125 | BM7V485 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,595.41 | 3,609 | BKX9NQ0 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $12,579.49 | 2,387 | BMVBZF5 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,455.52 | 7,414 | BFMLGR4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,356.82 | 2,646 | 2107437 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,039.00 | 4,013 | BDFKQ07 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,818.63 | 1,873 | BZ0G875 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,527.04 | 1,736 | BL5B6Z1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,363.84 | 6,176 | BN4JN37 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,268.40 | 10,244 | BM8NHS1 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,121.88 | 3,611 | BZ8FPH3 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $10,902.53 | 3,721 | BZC0D70 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,487.20 | 1,416 | BP81RK8 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,461.05 | 2,165 | BMF7DT9 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,284.46 | 3,426 | BYTYP72 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,061.00 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,974.50 | 1,158 | BQV0J03 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,686.60 | 3,341 | B5LL2C2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,345.57 | 2,179 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,293.33 | 2,089 | BPRB2N7 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,281.34 | 1,147 | BP2NYN2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,920.96 | 7,136 | BMYTJP4 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,904.19 | 1,981 | BP7L561 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,819.27 | 1,711 | BKDQKM6 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,808.40 | 7,230 | BNR5QT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,720.86 | 4,151 | BKRRKY7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,584.92 | 1,052 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,460.64 | 3,454 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,657.60 | 1,387 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,265.38 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,952.31 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,904.65 | 2,105 | BKTV702 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,887.73 | 2,541 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,753.89 | 2,303 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,393.32 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,376.80 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,882.10 | 8,555 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.48% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 22,618,679 | -- | 3,825 | -- |
| 29.01% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,838,751 | -- | 3,524 | -- |
| 27.77% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,951,744 | -- | 3,374 | -- |
| 21.72% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,605,410 | -- | 2,639 | -- |
| 20.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,860,324 | -- | 2,513 | -- |
| 5.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,743,170 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,003,599.84 | 21,003,600 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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