BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,975,486
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/12/2026- NAV
- NAV Change
- Market Price $82.65
- Market Price Change $+0.38
- Trading Volume (M) 5,455
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,975,486
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/12/2026- NAV
- NAV Change
- Market Price $82.65
- Market Price Change $+0.38
- Trading Volume (M) 5,455
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/12/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.84% | AMGN | AMGEN INC | -- | $3,482,025.60 | 9,803 | 2023607 |
| 4.73% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,406,790.73 | 7,657 | 2931034 |
| 4.43% | GILD | GILEAD SCIENCES INC | -- | $3,186,875.34 | 25,542 | 2369174 |
| 3.27% | REGN | REGENERON PHARMACEUTICALS | -- | $2,350,617.60 | 3,840 | 2730190 |
| 1.93% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,387,096.40 | 4,904 | B00FWN1 |
| 1.57% | RVMD | REVOLUTION MEDICINES INC | -- | $1,127,251.62 | 7,326 | BL71K91 |
| 1.51% | BIIB | BIOGEN INC | -- | $1,085,271.25 | 5,425 | 2455965 |
| 1.30% | ARGX | ARGENX SE - ADR | -- | $938,196.00 | 1,050 | BDVLM39 |
| 1.26% | ILMN | ILLUMINA INC | -- | $909,963.41 | 5,653 | 2613990 |
| 1.23% | UTHR | UNITED THERAPEUTICS CORP | -- | $884,455.20 | 1,620 | 2430412 |
| 1.21% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $868,976.19 | 15,837 | BMVP7Y0 |
| 1.11% | INCY | INCYTE CORP | -- | $798,672.27 | 7,359 | 2471950 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $794,858.40 | 26,460 | BMW4NZ9 |
| 1.08% | INSM | INSMED INC | -- | $779,668.80 | 7,968 | 2614487 |
| 1.01% | MRNA | MODERNA INC | -- | $728,686.00 | 14,600 | BGSXTS3 |
| 0.97% | VTRS | VIATRIS INC | -- | $701,471.20 | 42,565 | BMWS3X9 |
| 0.89% | GH | GUARDANT HEALTH INC | -- | $638,357.00 | 4,850 | BFXC911 |
| 0.82% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $593,029.12 | 3,712 | 2623911 |
| 0.73% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $524,524.00 | 2,275 | B4Q5ZN4 |
| 0.71% | EXEL | EXELIXIS INC | -- | $510,048.00 | 9,600 | 2576941 |
| 0.69% | ASND | ASCENDIS PHARMA A/S | -- | $496,304.56 | 2,276 | BWXJHM8 |
| 0.68% | MEDP | MEDPACE HOLDINGS INC | -- | $491,174.34 | 1,051 | BDCBC61 |
| 0.67% | AXSM | AXSOME THERAPEUTICS INC | -- | $482,271.30 | 1,890 | BYZR4X4 |
| 0.67% | BBIO | BRIDGEBIO PHARMA INC | -- | $478,755.60 | 7,167 | BK1KWG8 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $447,636.98 | 6,109 | BDJ0LS6 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $407,212.19 | 847 | BD59BS7 |
| 0.56% | SMMT | SUMMIT THERAPEUTICS INC | -- | $401,582.64 | 28,664 | BMTVQS7 |
| 0.56% | SNY | SANOFI-ADR | -- | $400,329.75 | 9,047 | 2964557 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $397,804.50 | 7,110 | 2437071 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $385,864.56 | 5,178 | BYQBFJ8 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $381,445.02 | 4,213 | BK6H543 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $343,407.60 | 1,080 | BD6JX35 |
| 0.46% | NUVL | NUVALENT INC-A | -- | $333,391.25 | 2,705 | BMVBZD3 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $319,392.95 | 4,553 | BBBSBJ5 |
| 0.43% | ONC | BEONE MEDICINES LTD-ADR | -- | $312,350.88 | 1,181 | BYYWPW6 |
| 0.43% | TEM | TEMPUS AI INC-CL A | -- | $307,195.68 | 6,424 | BSLSJJ0 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $303,298.00 | 4,364 | 2975098 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $274,310.82 | 1,029 | BQ721R4 |
| 0.38% | ALKS | ALKERMES PLC | -- | $272,897.64 | 6,163 | B3P6D26 |
| 0.37% | IBRX | IMMUNITYBIO INC | -- | $269,856.80 | 38,008 | BNSP0B8 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $260,080.49 | 3,017 | BMPRZV5 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $259,190.58 | 2,361 | BDCBCD8 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $252,923.26 | 7,523 | BJRFSB7 |
| 0.35% | PCVX | VAXCYTE INC | -- | $252,534.66 | 5,321 | BKPVGH6 |
| 0.33% | SYRE | SPYRE THERAPEUTICS INC | -- | $234,694.95 | 2,905 | BQBBDY8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $230,078.68 | 3,062 | B17VCN9 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $223,247.88 | 2,526 | BF2YWG4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $221,638.70 | 2,231 | BJDX8Y8 |
| 0.30% | ABVX | ABIVAX SA-ADR | -- | $219,265.05 | 2,271 | BLC89B2 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $198,666.20 | 6,002 | BLR6XK8 |
| 0.26% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $188,438.40 | 11,632 | BFNF1D6 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $188,077.44 | 736 | 2501578 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $187,445.07 | 10,431 | BT18HP9 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $186,005.88 | 3,123 | BRBCSP4 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $179,133.24 | 2,028 | BM9HHL5 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $177,931.52 | 4,624 | BTZRLN8 |
| 0.25% | TVTX | TRAVERE THERAPEUTICS INC | -- | $177,404.36 | 3,409 | BLFGJD5 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $176,790.00 | 3,550 | BDHF4K6 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,681.56 | 4,423 | BLB0YQ9 |
| 0.24% | TWST | TWIST BIOSCIENCE CORP | -- | $172,601.22 | 2,266 | BGKG6G7 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $166,691.14 | 3,773 | BFZQ0L8 |
| 0.22% | ERAS | ERASCA INC | -- | $160,788.20 | 11,444 | BNLYBF3 |
| 0.22% | XENE | XENON PHARMACEUTICALS INC | -- | $160,155.40 | 3,074 | BRJ3GY4 |
| 0.21% | TNGX | TANGO THERAPEUTICS INC | -- | $154,019.32 | 4,978 | BP2P6L0 |
| 0.19% | VCYT | VERACYTE INC | -- | $139,055.54 | 2,938 | BFTWZY0 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $138,135.78 | 3,966 | BKY5JZ8 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $133,467.84 | 3,872 | BDD19F8 |
| 0.18% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $132,930.27 | 6,303 | 2713317 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $129,260.80 | 4,252 | BP8JSP4 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $126,992.58 | 5,863 | BD2B4V0 |
| 0.17% | TXG | 10X GENOMICS INC-CLASS A | -- | $125,482.84 | 4,351 | BKS3RS7 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $125,033.21 | 1,789 | BKVF0J2 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $123,638.40 | 2,880 | BQS9486 |
| 0.16% | ALMS | ALUMIS INC | -- | $112,877.10 | 4,674 | BPLQG36 |
| 0.16% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $111,986.14 | 3,122 | BMX9K07 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $111,831.06 | 4,587 | BKX9VD3 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $110,722.53 | 6,087 | BN15WD1 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $109,356.01 | 3,767 | BK6L288 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $101,301.48 | 2,196 | BMFD115 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $100,179.20 | 5,692 | BJ5FZ74 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $97,834.86 | 6,606 | BN2R582 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $97,447.35 | 1,573 | BMH5RL1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $95,933.89 | 1,411 | BMGJZJ8 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $94,149.20 | 2,120 | B72ZBG4 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $94,069.08 | 3,246 | BK0VHF6 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $91,203.75 | 3,685 | BV2DHY6 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $90,309.36 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $88,109.22 | 1,698 | BRXB0C0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $86,953.85 | 3,571 | BJ62Z18 |
| 0.12% | GRAL | GRAIL INC | -- | $86,124.15 | 1,439 | BSLSSX7 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $80,657.70 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $77,739.48 | 4,914 | BFWLC09 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $76,805.30 | 2,255 | BFXC933 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $74,836.02 | 4,209 | BYSS4X4 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,744.40 | 2,140 | BKSGZN7 |
| 0.10% | PHVS | PHARVARIS NV | -- | $72,714.24 | 2,367 | BMZ2X38 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $72,289.05 | 8,805 | B9NSBM2 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,958.06 | 8,049 | BNZB1X8 |
| 0.10% | VCEL | VERICEL CORP | -- | $70,237.50 | 1,875 | BSBMN89 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $69,088.50 | 2,925 | BP9N0G0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,794.40 | 830 | BCDWBX6 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $67,737.60 | 1,764 | BR3T9B6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $67,383.82 | 4,742 | BJH9ZN0 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $64,443.90 | 3,802 | BMVLGP2 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $63,810.36 | 2,166 | BCBVTX1 |
| 0.09% | QURE | UNIQURE NV | -- | $63,548.85 | 2,305 | BJFSR88 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $63,286.08 | 2,766 | BPCQZY9 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $62,950.02 | 2,111 | BJQ05Z6 |
| 0.09% | INVA | INNOVIVA INC | -- | $62,307.60 | 2,740 | BDDXF67 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $62,146.56 | 15,232 | BF0DMK7 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,785.55 | 19,297 | BM9FJ13 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $59,665.32 | 2,379 | BBC9WC7 |
| 0.08% | SEPN | SEPTERNA INC | -- | $59,569.15 | 1,657 | BQNKXX2 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $59,513.25 | 3,261 | BN7Q7R7 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $59,326.25 | 3,875 | B8DPDT7 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $59,303.92 | 1,651 | BQKXDX4 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $59,220.81 | 4,059 | BPCK358 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $58,875.58 | 1,658 | BQXJKH2 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $58,735.16 | 11,209 | BL53SR3 |
| 0.08% | PGEN | PRECIGEN INC | -- | $58,206.00 | 13,080 | BKM5C84 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $57,830.88 | 10,128 | BNC1BX1 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $57,359.61 | 1,023 | BDRW1L7 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $56,938.40 | 3,455 | BRXYZ57 |
| 0.07% | NVAX | NOVAVAX INC | -- | $53,484.24 | 6,023 | BJDQXG4 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $53,278.26 | 1,974 | BMVNDH9 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $52,908.59 | 4,369 | BYZM6C2 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $52,641.68 | 13,429 | BWJDYK1 |
| 0.07% | ARDX | ARDELYX INC | -- | $51,585.54 | 9,066 | BN89V40 |
| 0.07% | HROW | HARROW INC | -- | $51,566.80 | 1,370 | BHNDW86 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $51,415.60 | 1,730 | BZ7PJQ1 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $51,386.23 | 2,818 | BP7KZP7 |
| 0.07% | ALVO | ALVOTECH SA | -- | $50,915.70 | 12,210 | BPNTJ34 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $50,819.67 | 2,343 | BQB42F1 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,024.10 | 5,810 | BK4PZ38 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $49,511.40 | 537 | BNSP8K3 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $48,449.28 | 2,294 | BP6C0S2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,944.16 | 1,621 | BLCD809 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,634.58 | 1,527 | BMGTLY5 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $42,760.90 | 1,778 | BSRK699 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $42,122.96 | 3,487 | BMC3HS7 |
| 0.06% | MNKD | MANNKIND CORP | -- | $41,683.74 | 11,389 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,649.86 | 6,134 | BLR7H87 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $40,855.20 | 6,960 | BYZG9R0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,598.08 | 1,172 | BX7RSN3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $39,897.86 | 3,062 | BMGS7L1 |
| 0.05% | SVRA | SAVARA INC | -- | $39,576.24 | 7,524 | BYXGN81 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $39,263.40 | 1,983 | BQB42H3 |
| 0.05% | ABSI | ABSCI CORP | -- | $37,814.80 | 5,561 | BN94K69 |
| 0.05% | PSNL | PERSONALIS INC | -- | $37,103.71 | 3,869 | BJQ0608 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $36,434.22 | 3,054 | BYP80F1 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,682.56 | 3,656 | BMCR7V2 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,456.40 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,370.05 | 1,495 | B3X26D8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $33,690.93 | 1,677 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $33,426.63 | 2,711 | BGCYWN8 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,337.28 | 992 | BGL0JK3 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,200.00 | 1,875 | BMNDK09 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $30,689.97 | 3,711 | BKVDFF7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,523.56 | 2,251 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,288.60 | 7,110 | BZ0QMB7 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $30,197.44 | 2,912 | BJLKVS6 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,934.50 | 2,185 | BM90J52 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $29,234.94 | 2,962 | BMZ4LN0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $29,122.90 | 3,218 | BYZD465 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $28,936.16 | 1,604 | BT9K6D8 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,530.25 | 2,975 | BFYQFJ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,836.55 | 8,837 | BBNBTD2 |
| 0.04% | GERN | GERON CORP | -- | $27,142.30 | 23,602 | 2370381 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $27,110.64 | 3,053 | BDDVW37 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $26,941.80 | 5,410 | BMCWKZ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,940.62 | 1,934 | BQS7491 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $26,395.32 | 9,849 | BMFJJ97 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,349.95 | 2,083 | BLFBZ32 |
| 0.04% | CRMD | CORMEDIX INC | -- | $25,442.14 | 2,911 | BJ0LT31 |
| 0.04% | ANNX | ANNEXON INC | -- | $25,193.79 | 5,349 | BMVV9R5 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,057.39 | 763 | BL95N25 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,171.92 | 2,707 | BP0TQC5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,091.85 | 2,105 | BMFK3H6 |
| 0.03% | OMER | OMEROS CORP | -- | $22,903.17 | 2,622 | B4NB858 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,770.00 | 1,100 | BKLCWZ3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,075.20 | 672 | BQD3J33 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $22,056.96 | 1,536 | BRJJYT3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,002.20 | 6,028 | B3MZ6K5 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,661.83 | 1,269 | BD9GVY0 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,984.04 | 693 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,563.20 | 2,880 | BQHN6C7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,262.88 | 4,459 | BYV2W40 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,857.65 | 6,265 | BYWVTY5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,810.87 | 4,511 | BYVQJ96 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,517.58 | 6,673 | BPBJFM7 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $18,045.72 | 1,023 | BS2CR64 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,911.54 | 2,363 | BDZ30Q0 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,012.16 | 2,112 | BSMLR16 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,644.55 | 1,885 | BKLXFX5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,616.10 | 571 | BS2F741 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,409.25 | 1,989 | B91XRN2 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,131.81 | 2,397 | BDRJH21 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,876.96 | 2,134 | B2Q9833 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,837.20 | 548 | B292NQ7 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,785.20 | 8,308 | BFZNYB7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $15,057.09 | 2,349 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,623.53 | 11,163 | B4N8MH9 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $14,075.10 | 3,609 | BKX9NQ0 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,928.58 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,773.07 | 1,879 | B7F2TY6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,353.12 | 1,124 | BPRBTY7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,971.61 | 2,889 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,831.82 | 2,186 | B12W3P6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,756.80 | 1,072 | B9L5200 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,474.18 | 1,873 | BZ0G875 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,181.70 | 1,997 | BRCFFK6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,086.91 | 4,631 | BFY7DC4 |
| 0.02% | OABI | OMNIAB INC | -- | $12,080.94 | 5,322 | BN13S71 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,785.89 | 2,697 | BQ6C357 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,613.84 | 1,736 | BL5B6Z1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,565.84 | 7,414 | BFMLGR4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,430.72 | 2,646 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,418.75 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,035.75 | 4,013 | BDFKQ07 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,993.28 | 6,176 | BN4JN37 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $10,706.57 | 3,557 | BK5MWR1 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,624.50 | 787 | BTNMG41 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,001.53 | 2,387 | BMVBZF5 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,147.36 | 1,416 | BP81RK8 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,049.70 | 2,165 | BMF7DT9 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,027.50 | 3,611 | BZ8FPH3 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,595.51 | 3,721 | BZC0D70 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,565.00 | 3,426 | BYTYP72 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,564.90 | 2,089 | BPRB2N7 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,500.80 | 2,464 | BJDX8Z9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,320.20 | 1,981 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,018.40 | 3,341 | B5LL2C2 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,887.88 | 10,244 | BM8NHS1 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,839.66 | 1,158 | BQV0J03 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,822.68 | 1,387 | 2517058 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,735.00 | 5,525 | BRK0149 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,626.50 | 2,179 | BY7RB53 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,528.48 | 7,136 | BMYTJP4 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,432.56 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,332.44 | 1,052 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,929.55 | 1,711 | BKDQKM6 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,844.64 | 7,230 | BNR5QT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,184.99 | 4,151 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,702.94 | 8,012 | BNNXX52 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,509.13 | 3,454 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,333.94 | 2,743 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,053.28 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,735.27 | 2,541 | BMTX3D7 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,683.75 | 2,105 | BKTV702 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,135.60 | 804 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,742.44 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,385.05 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 33.90% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 24,395,399 | -- | 4,108 | -- |
| 29.08% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,927,309 | -- | 3,524 | -- |
| 25.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,219,349 | -- | 3,068 | -- |
| 21.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,671,728 | -- | 2,639 | -- |
| 20.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,923,476 | -- | 2,513 | -- |
| 5.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,759,077 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,006,591.86 | 21,006,592 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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