BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.67% | 24.99% | 47.98% | 51.34% | 69.14% | 43.98% | 6.41% | 12.60% | 18.47% | 04/07/2010 |
| BIB Market Price | 4.40% | 24.85% | 47.78% | 51.20% | 68.94% | 43.92% | 6.39% | 12.57% | 18.46% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -0.91% | 14.69% | 41.74% | 44.83% | 94.28% | 35.26% | 4.58% | 9.38% | 18.26% | 04/07/2010 |
| BIB NAV | -1.01% | 14.41% | 41.46% | 44.59% | 93.99% | 35.10% | 4.57% | 9.35% | 18.24% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $107,350,129
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/10/2026- NAV
- NAV Change
- Market Price $122.13
- Market Price Change $-2.00
- Trading Volume (M) 5,135
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $107,350,129
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/10/2026- NAV
- NAV Change
- Market Price $122.13
- Market Price Change $-2.00
- Trading Volume (M) 5,135
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2027. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2026
Holdings
as of 11/10/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.58% | GILD | GILEAD SCIENCES INC | -- | $5,988,993.50 | 35,050 | 2369174 |
| 5.17% | AMGN | AMGEN INC | -- | $5,551,124.36 | 11,932 | 2023607 |
| 4.81% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,160,575.91 | 9,419 | 2931034 |
| 3.92% | MRNA | MODERNA INC | -- | $4,204,412.46 | 16,762 | BGSXTS3 |
| 3.62% | REGN | REGENERON PHARMACEUTICALS | -- | $3,889,590.76 | 4,246 | 2730190 |
| 1.62% | RVMD | REVOLUTION MEDICINES INC | -- | $1,737,346.94 | 8,999 | BL71K91 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,571,163.00 | 6,204 | 2455965 |
| 1.27% | ILMN | ILLUMINA INC | -- | $1,362,529.40 | 6,340 | 2613990 |
| 1.21% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $1,298,298.30 | 18,694 | BMVP7Y0 |
| 1.16% | ROIV | ROIVANT SCIENCES LTD | -- | $1,249,169.13 | 30,327 | BMW4NZ9 |
| 1.04% | ARGX | ARGENX SE - ADR | -- | $1,113,396.30 | 1,146 | BDVLM39 |
| 1.02% | INSM | INSMED INC | -- | $1,095,484.32 | 9,168 | 2614487 |
| 0.99% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,060,675.22 | 1,802 | 2430412 |
| 0.95% | INCY | INCYTE CORP | -- | $1,023,753.00 | 8,510 | 2471950 |
| 0.94% | VTRS | VIATRIS INC | -- | $1,005,470.40 | 48,224 | BMWS3X9 |
| 0.82% | GH | GUARDANT HEALTH INC | -- | $875,241.90 | 5,634 | BFXC911 |
| 0.79% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $851,913.52 | 5,618 | B00FWN1 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $778,840.88 | 1,172 | BDCBC61 |
| 0.68% | EXEL | EXELIXIS INC | -- | $734,243.74 | 10,403 | 2576941 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $721,720.38 | 4,267 | 2623911 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $668,796.75 | 2,725 | B4Q5ZN4 |
| 0.62% | ASND | ASCENDIS PHARMA A/S | -- | $663,285.15 | 2,585 | BWXJHM8 |
| 0.62% | BBIO | BRIDGEBIO PHARMA INC | -- | $662,244.06 | 8,418 | BK1KWG8 |
| 0.59% | ONC | BEONE MEDICINES LTD-ADR | -- | $638,120.00 | 1,505 | BYYWPW6 |
| 0.56% | SMMT | SUMMIT THERAPEUTICS INC | -- | $597,180.19 | 33,493 | BMTVQS7 |
| 0.55% | TEM | TEMPUS AI INC-CL A | -- | $593,096.56 | 7,364 | BSLSJJ0 |
| 0.46% | HALO | HALOZYME THERAPEUTICS INC | -- | $490,802.68 | 4,766 | 2975098 |
| 0.44% | KYMR | KYMERA THERAPEUTICS INC | -- | $476,873.60 | 3,490 | BMPRZV5 |
| 0.43% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $464,295.51 | 8,127 | 2437071 |
| 0.41% | SNY | SANOFI-ADR | -- | $436,529.73 | 9,051 | 2964557 |
| 0.39% | BNTX | BIONTECH SE-ADR | -- | $423,927.81 | 4,861 | BK6H543 |
| 0.39% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $420,054.60 | 971 | BD59BS7 |
| 0.39% | PCVX | VAXCYTE INC | -- | $414,617.28 | 6,248 | BKPVGH6 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $395,655.48 | 1,172 | BQ721R4 |
| 0.36% | SYRE | SPYRE THERAPEUTICS INC | -- | $386,784.96 | 3,702 | BQBBDY8 |
| 0.35% | KRYS | KRYSTAL BIOTECH INC | -- | $380,979.50 | 1,243 | BD6JX35 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $370,218.42 | 2,717 | BDCBCD8 |
| 0.34% | TWST | TWIST BIOSCIENCE CORP | -- | $368,114.18 | 2,786 | BGKG6G7 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $329,315.50 | 2,890 | BF2YWG4 |
| 0.31% | CYTK | CYTOKINETICS INC | -- | $327,922.66 | 5,837 | BBBSBJ5 |
| 0.30% | ALKS | ALKERMES PLC | -- | $327,334.68 | 7,044 | B3P6D26 |
| 0.30% | TXG | 10X GENOMICS INC-CLASS A | -- | $317,456.30 | 5,047 | BKS3RS7 |
| 0.29% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $312,639.74 | 14,623 | BFNF1D6 |
| 0.29% | AXSM | AXSOME THERAPEUTICS INC | -- | $310,134.00 | 2,200 | BYZR4X4 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $309,677.12 | 8,672 | BJRFSB7 |
| 0.28% | ORKA | ORUKA THERAPEUTICS INC | -- | $304,410.00 | 2,780 | BKVF0J2 |
| 0.28% | IBRX | IMMUNITYBIO INC | -- | $300,125.52 | 44,496 | BNSP0B8 |
| 0.27% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $290,619.00 | 5,931 | BYQBFJ8 |
| 0.27% | CAI | CARIS LIFE SCIENCES INC | -- | $289,837.52 | 11,864 | BT18HP9 |
| 0.27% | KOD | KODIAK SCIENCES INC | -- | $285,062.28 | 2,638 | BFXC933 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $270,366.08 | 3,722 | BRBCSP4 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $262,951.92 | 837 | 2501578 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $257,483.34 | 2,727 | BJDX8Y8 |
| 0.23% | SUPN | SUPERNUS INC | -- | $250,498.75 | 8,713 | BTZRLN8 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $245,424.00 | 5,113 | BFZQ0L8 |
| 0.22% | GRAL | GRAIL INC | -- | $234,012.24 | 1,876 | BSLSSX7 |
| 0.21% | COGT | COGENT BIOSCIENCES INC | -- | $230,497.40 | 7,285 | BLR6XK8 |
| 0.21% | ERAS | ERASCA INC | -- | $227,308.32 | 14,684 | BNLYBF3 |
| 0.21% | PTCT | PTC THERAPEUTICS INC | -- | $224,810.70 | 3,505 | B17VCN9 |
| 0.21% | GMAB | GENMAB A/S -SP ADR | -- | $220,118.97 | 4,071 | BBC9WC7 |
| 0.20% | ABVX | ABIVAX SA-ADR | -- | $216,090.00 | 2,401 | BLC89B2 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $212,176.80 | 4,560 | BKY5JZ8 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $205,776.42 | 3,958 | BLFGJD5 |
| 0.18% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $196,712.00 | 6,700 | BJ5FZ74 |
| 0.18% | IONS | IONIS PHARMACEUTICALS INC | -- | $196,709.82 | 6,978 | BDJ0LS6 |
| 0.18% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $195,404.24 | 5,641 | BV2DHY6 |
| 0.18% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $192,700.56 | 2,028 | BRXB0C0 |
| 0.17% | RLAY | RELAY THERAPEUTICS INC | -- | $183,448.00 | 9,200 | BN2R582 |
| 0.17% | CRSP | CRISPR THERAPEUTICS AG | -- | $183,309.00 | 4,060 | BDHF4K6 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $172,019.70 | 7,079 | BP2P6L0 |
| 0.16% | ABCL | ABCELLERA BIOLOGICS INC | -- | $169,505.84 | 13,604 | BL53SR3 |
| 0.16% | XENE | XENON PHARMACEUTICALS INC | -- | $168,291.74 | 4,066 | BRJ3GY4 |
| 0.15% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $162,864.79 | 5,269 | BPCK358 |
| 0.15% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $157,491.20 | 3,076 | BMFD115 |
| 0.14% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $153,657.36 | 19,017 | BF0DMK7 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $144,510.65 | 5,277 | BKX9VD3 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $142,565.73 | 1,931 | BMH5RL1 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $140,474.88 | 7,839 | BN15WD1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $136,439.68 | 1,612 | BMGJZJ8 |
| 0.12% | DNLI | DENALI THERAPEUTICS INC | -- | $133,213.35 | 6,711 | BD2B4V0 |
| 0.12% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $132,219.24 | 7,233 | 2713317 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $128,651.00 | 4,052 | BK0VHF6 |
| 0.12% | VCEL | VERICEL CORP | -- | $126,914.50 | 2,150 | BSBMN89 |
| 0.11% | XNCR | XENCOR INC | -- | $122,975.58 | 3,122 | BGCYWN8 |
| 0.11% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $121,162.82 | 7,654 | BLR7H87 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $119,136.01 | 9,403 | B9NSBM2 |
| 0.11% | MBX | MBX BIOSCIENCES INC | -- | $113,899.26 | 2,022 | BQXJKH2 |
| 0.10% | BEAM | BEAM THERAPEUTICS INC | -- | $109,050.40 | 4,336 | BK6L288 |
| 0.10% | SEPN | SEPTERNA INC | -- | $102,586.40 | 1,960 | BQNKXX2 |
| 0.09% | PHVS | PHARVARIS NV | -- | $100,202.52 | 2,948 | BMZ2X38 |
| 0.09% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $96,245.24 | 5,018 | BP8JSP4 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $93,719.34 | 2,979 | BPCQZY9 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $93,417.60 | 7,104 | BK4PZ38 |
| 0.09% | REPL | REPLIMUNE GROUP INC | -- | $92,072.40 | 3,955 | BDDVW37 |
| 0.08% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,035.50 | 5,585 | BFWLC09 |
| 0.08% | VERA | VERA THERAPEUTICS INC | -- | $90,840.75 | 3,025 | BL55460 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $89,191.62 | 5,982 | BJH9ZN0 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $85,410.27 | 3,993 | BRXYZ57 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $82,669.40 | 2,332 | BSRK699 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $81,996.20 | 2,444 | BKSGZN7 |
| 0.08% | VCYT | VERACYTE INC | -- | $81,178.44 | 3,374 | BFTWZY0 |
| 0.08% | ETON | ETON PHARMACEUTICALS INC | -- | $81,048.00 | 1,200 | BGL0JK3 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $80,781.84 | 10,728 | 2100362 |
| 0.07% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,786.25 | 22,475 | BM9FJ13 |
| 0.07% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $79,622.32 | 2,507 | BCBVTX1 |
| 0.07% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $78,925.47 | 3,867 | BMX9K07 |
| 0.07% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $78,495.00 | 1,500 | BS2CR64 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $78,223.46 | 2,737 | BQB42H3 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $74,751.20 | 3,440 | BQS9486 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $73,684.68 | 2,708 | BJQ05Z6 |
| 0.07% | SRPT | SAREPTA THERAPEUTICS INC | -- | $72,806.28 | 4,434 | B8DPDT7 |
| 0.07% | ABSI | ABSCI CORP | -- | $71,823.88 | 7,204 | BN94K69 |
| 0.07% | PSNL | PERSONALIS INC | -- | $71,190.04 | 4,483 | BJQ0608 |
| 0.07% | NVAX | NOVAVAX INC | -- | $70,624.80 | 6,924 | BJDQXG4 |
| 0.06% | ALVO | ALVOTECH SA | -- | $69,291.12 | 14,199 | BPNTJ34 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $69,173.28 | 4,356 | BMVLGP2 |
| 0.06% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,756.25 | 965 | BCDWBX6 |
| 0.06% | PGEN | PRECIGEN INC | -- | $67,940.12 | 15,031 | BKM5C84 |
| 0.06% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $66,787.32 | 4,138 | BJ62Z18 |
| 0.06% | QURE | UNIQURE NV | -- | $66,131.52 | 2,912 | BJFSR88 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,701.94 | 5,882 | BYZM6C2 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $62,979.10 | 1,945 | BLCD809 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $61,084.26 | 1,674 | B3X26D8 |
| 0.06% | OCUL | OCULAR THERAPEUTIX INC | -- | $60,937.59 | 9,219 | BNZB1X8 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $60,184.72 | 1,244 | BDRW1L7 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $58,473.45 | 13,678 | BNC1BX1 |
| 0.05% | INVA | INNOVIVA INC | -- | $57,869.64 | 3,033 | BDDXF67 |
| 0.05% | NVCR | NOVOCURE LTD | -- | $57,727.28 | 4,888 | BYSS4X4 |
| 0.05% | MLYS | MINERALYS THERAPEUTICS INC | -- | $57,594.72 | 3,711 | BP9N0G0 |
| 0.05% | MNKD | MANNKIND CORP | -- | $57,100.77 | 13,499 | BF081J4 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $56,352.36 | 2,881 | BP6C0S2 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,906.37 | 617 | BNSP8K3 |
| 0.05% | TYRA | TYRA BIOSCIENCES INC | -- | $52,605.00 | 2,505 | BMVNDH9 |
| 0.05% | OMER | OMEROS CORP | -- | $52,574.70 | 3,039 | B4NB858 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $52,283.44 | 2,014 | BR3T9B6 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $51,994.25 | 5,621 | BMC3HS7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $51,956.64 | 2,052 | BZ7PJQ1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $51,872.10 | 1,785 | BNFWZS4 |
| 0.05% | ZLAB | ZAI LAB LTD-ADR | -- | $49,424.10 | 1,870 | BD9GVY0 |
| 0.05% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $49,164.30 | 6,255 | BMCWKZ2 |
| 0.05% | VOR | VOR BIOPHARMA INC | -- | $48,567.48 | 2,483 | BRJJYT3 |
| 0.04% | HROW | HARROW INC | -- | $47,786.64 | 1,574 | BHNDW86 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $44,126.44 | 1,282 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $42,439.92 | 8,626 | BYXGN81 |
| 0.04% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $40,147.47 | 3,531 | BYP80F1 |
| 0.04% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $39,045.67 | 1,973 | BL5B6Z1 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $38,778.22 | 4,031 | BFYQFJ2 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $38,767.41 | 4,351 | BKVDFF7 |
| 0.04% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $37,600.50 | 3,581 | BP7KZP7 |
| 0.03% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $35,568.52 | 3,748 | BN7Q7R7 |
| 0.03% | ALMS | ALUMIS INC | -- | $34,771.20 | 5,433 | BPLQG36 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $34,425.44 | 784 | BQD3J33 |
| 0.03% | ANNX | ANNEXON INC | -- | $33,507.39 | 7,959 | BMVV9R5 |
| 0.03% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $33,426.02 | 1,366 | BX7RSN3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $33,362.16 | 6,936 | B3MZ6K5 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $33,300.45 | 4,353 | BP81R42 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $32,272.17 | 4,501 | BQHN6C7 |
| 0.03% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,728.92 | 8,306 | BZ0QMB7 |
| 0.03% | ARDX | ARDELYX INC | -- | $31,487.61 | 10,461 | BN89V40 |
| 0.03% | OABI | OMNIAB INC | -- | $31,125.30 | 6,103 | BN13S71 |
| 0.03% | JANX | JANUX THERAPEUTICS INC | -- | $30,894.64 | 2,566 | BMFX8Y7 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $30,791.99 | 2,201 | BQS7491 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $30,656.40 | 885 | BL95N25 |
| 0.03% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,537.81 | 12,567 | BMFJJ97 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,332.23 | 2,701 | BM90J52 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $30,022.85 | 3,211 | BP0TQC5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $29,704.64 | 2,492 | BLFBZ32 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $29,694.60 | 7,614 | BPBJFM7 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $29,232.00 | 13,050 | B4N8MH9 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $28,894.74 | 2,319 | BKLXFX5 |
| 0.03% | BCAX | BICARA THERAPEUTICS INC | -- | $28,269.86 | 2,777 | BQB42F1 |
| 0.03% | KURA | KURA ONCOLOGY INC | -- | $28,266.38 | 3,734 | BYZD465 |
| 0.03% | WVE | WAVE LIFE SCIENCES INC | -- | $28,207.52 | 8,272 | C08GM13 |
| 0.03% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $28,150.65 | 2,585 | BP2NYN2 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,977.55 | 2,627 | BMFK3H6 |
| 0.03% | AVBP | ARRIVENT BIOPHARMA INC | -- | $27,924.30 | 2,070 | BMGTLY5 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $26,702.71 | 3,673 | BMZ4LN0 |
| 0.02% | GERN | GERON CORP | -- | $26,278.07 | 26,974 | 2370381 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $25,642.85 | 6,179 | BYV2W40 |
| 0.02% | RGNX | REGENXBIO INC | -- | $21,301.30 | 2,770 | BZ0G875 |
| 0.02% | NGNE | NEUROGENE INC | -- | $21,209.92 | 839 | BS2F741 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $20,847.84 | 624 | B292NQ7 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $19,677.42 | 2,254 | BP7L561 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,610.10 | 2,421 | B2Q9833 |
| 0.02% | ARVN | ARVINAS INC | -- | $18,988.48 | 2,744 | BDZ30Q0 |
| 0.02% | EOLS | EVOLUS INC | -- | $18,870.51 | 2,771 | BDRJH21 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,546.88 | 5,269 | BYVQJ96 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $18,491.22 | 3,396 | BJLKVS6 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $18,438.24 | 2,154 | B91XRN2 |
| 0.02% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,111.06 | 9,147 | BYWVTY5 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $18,015.40 | 820 | BPBPCG8 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,631.24 | 2,166 | B7F2TY6 |
| 0.02% | CRMD | CORMEDIX INC | -- | $17,565.27 | 3,271 | BJ0LT31 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,219.00 | 1,028 | BTNMG41 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,149.74 | 6,447 | BZ8FPH3 |
| 0.01% | ALT | ALTIMMUNE INC | -- | $15,842.04 | 8,166 | BFY7DC4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $15,492.00 | 5,164 | BKX9NQ0 |
| 0.01% | SPRY | ARS PHARMACEUTICALS INC | -- | $14,904.75 | 4,175 | BMCR7V2 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,593.92 | 1,382 | BPRBTY7 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $14,456.79 | 2,523 | BPRB2N7 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,141.40 | 3,367 | BLN9Z50 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,710.84 | 1,222 | B9L5200 |
| 0.01% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $13,516.28 | 14,504 | BFZNYB7 |
| 0.01% | PEPG | PEPGEN INC | -- | $13,405.88 | 2,908 | BMTX3D7 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $13,187.68 | 2,596 | BSMLR16 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $11,911.44 | 3,202 | BJDX8Z9 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $11,731.09 | 4,361 | BMXNGZ6 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,292.05 | 4,609 | BDFKQ07 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $11,192.88 | 1,192 | BKC9SX3 |
| 0.01% | BIOA | BIOAGE LABS INC | -- | $11,126.50 | 1,925 | BT9K6D8 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,115.72 | 8,421 | BFMLGR4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,690.56 | 8,352 | BNR5QT9 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $10,538.64 | 3,444 | BQ6C357 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,452.75 | 2,715 | BMVBZF5 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $10,355.04 | 2,538 | B12W3P6 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $10,319.65 | 7,117 | BK5MWR1 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $10,115.56 | 1,588 | 2517058 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,782.88 | 4,272 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $9,440.08 | 3,016 | 2107437 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,578.50 | 1,634 | BP81RK8 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $7,770.62 | 2,299 | BRCFFK6 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,762.56 | 832 | BM7V485 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,236.09 | 1,961 | BKDQKM6 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,107.63 | 12,374 | BM8NHS1 |
| 0.01% | SION | SIONNA THERAPEUTICS INC | -- | $7,018.90 | 1,897 | BQKXDX4 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,880.58 | 11,662 | BMYTJP4 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,711.89 | 3,191 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,708.26 | 3,502 | BLBR8D5 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $5,403.80 | 1,318 | BQV0J03 |
| -- | FHTX | FOGHORN THERAPEUTICS INC | -- | $4,734.80 | 2,492 | BMF7DT9 |
| -- | VYGR | VOYAGER THERAPEUTICS INC | -- | $4,719.45 | 2,586 | BY7RB53 |
| -- | CDXS | CODEXIS INC | -- | $4,596.00 | 4,596 | B5LL2C2 |
| -- | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $4,397.96 | 3,892 | BYTYP72 |
| -- | CHRS | COHERUS ONCOLOGY INC | -- | $4,156.88 | 6,486 | BRK0149 |
| -- | NBP | NOVABRIDGE BIOSCIENCES | -- | $4,052.79 | 4,712 | BKRRKY7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,845.55 | 2,411 | BKTV702 |
| -- | NMRA | NEUMORA THERAPEUTICS INC | -- | $3,680.54 | 7,888 | BN4JN37 |
| -- | TNYA | TENAYA THERAPEUTICS INC | -- | $3,488.09 | 9,412 | BNNXX52 |
| -- | GOSS | GOSSAMER BIO INC | -- | $2,887.68 | 256 | C0BCTT5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,713.68 | 4,845 | BNNXX18 |
| -- | CRBU | CARIBOU BIOSCIENCES INC | -- | $1,846.39 | 4,499 | BNYJR68 |
| -- | EYPT | EYEPOINT INC | -- | $1,462.03 | 3,618 | BMGS7L1 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $1,257.66 | 918 | BTXQTX3 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | -- | COHERUS ONCOLOGY INC COMMON STOCK USD | -- | $00.00 | 5,356 | -- |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 37,516,257 | -- | 5,080 | -- |
| 30.19% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 32,405,775 | -- | 4,388 | -- |
| 27.94% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 29,998,236 | -- | 4,062 | -- |
| 18.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 19,489,253 | -- | 2,639 | -- |
| 17.29% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 18,558,731 | -- | 2,513 | -- |
| 9.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 10,405,592 | -- | 1,409 | -- |
| -- | IQMM | PROSHARES GENIUS MONEY MARKET ETF | -- | $17,015,300.00 | 170,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $23,936,726.18 | 23,936,726 | -- |
Index
as of 9/30/2026
- Total Number of Holdings245
- Price/Book Ratio6.08
- Dividend Yield ( % )0.49
- Avg. Index Market Capitalization$7.91 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: Why hedge?—A tool for managing risk
Periods of uncertainty often make investors want to reduce risk in their portfolios. A hedging strategy may help investors manage risk while remaining invested for long-term growth.
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