BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,508,339
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/23/2026- NAV
- NAV Change
- Market Price $84.58
- Market Price Change $-2.44
- Trading Volume (M) 23,740
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,508,339
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/23/2026- NAV
- NAV Change
- Market Price $84.58
- Market Price Change $-2.44
- Trading Volume (M) 23,740
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/23/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.81% | AMGN | AMGEN INC | -- | $3,824,710.02 | 10,971 | 2023607 |
| 4.81% | GILD | GILEAD SCIENCES INC | -- | $3,820,901.24 | 28,591 | 2369174 |
| 4.69% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,728,807.00 | 8,570 | 2931034 |
| 4.14% | REGN | REGENERON PHARMACEUTICALS | -- | $3,292,353.96 | 4,298 | 2730190 |
| 2.17% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,721,451.94 | 5,486 | B00FWN1 |
| 1.61% | INSM | INSMED INC | -- | $1,282,963.60 | 8,920 | 2614487 |
| 1.43% | BIIB | BIOGEN INC | -- | $1,140,619.48 | 6,071 | 2455965 |
| 1.39% | RVMD | REVOLUTION MEDICINES INC | -- | $1,102,736.00 | 8,200 | BL71K91 |
| 1.31% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,038,577.05 | 1,813 | 2430412 |
| 1.16% | ARGX | ARGENX SE - ADR | -- | $925,053.30 | 1,174 | BDVLM39 |
| 1.11% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $880,017.92 | 17,728 | BMVP7Y0 |
| 1.09% | MRNA | MODERNA INC | -- | $863,674.70 | 16,342 | BGSXTS3 |
| 1.05% | ROIV | ROIVANT SCIENCES LTD | -- | $833,534.94 | 29,621 | BMW4NZ9 |
| 1.00% | ILMN | ILLUMINA INC | -- | $793,784.32 | 6,328 | 2613990 |
| 0.99% | INCY | INCYTE CORP | -- | $786,386.39 | 8,237 | 2471950 |
| 0.90% | SMMT | SUMMIT THERAPEUTICS INC | -- | $714,599.76 | 32,088 | BMTVQS7 |
| 0.88% | VTRS | VIATRIS INC | -- | $702,822.75 | 47,649 | BMWS3X9 |
| 0.72% | BBIO | BRIDGEBIO PHARMA INC | -- | $575,008.41 | 8,023 | BK1KWG8 |
| 0.72% | -- | ASCENDIS PHARMA A/S | -- | $573,075.00 | 2,547 | -- |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $540,809.26 | 4,154 | 2623911 |
| 0.64% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $509,298.12 | 2,547 | B4Q5ZN4 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $506,553.33 | 6,837 | BDJ0LS6 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $497,715.40 | 4,715 | BK6H543 |
| 0.62% | EXEL | EXELIXIS INC | -- | $494,945.40 | 10,748 | 2576941 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $492,803.00 | 950 | BD59BS7 |
| 0.61% | SNY | SANOFI-ADR | -- | $481,336.31 | 10,127 | 2964557 |
| 0.60% | GH | GUARDANT HEALTH INC | -- | $476,782.62 | 5,426 | BFXC911 |
| 0.58% | MEDP | MEDPACE HOLDINGS INC | -- | $461,875.08 | 1,174 | BDCBC61 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $431,296.80 | 5,797 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $429,626.82 | 7,959 | 2437071 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $396,648.63 | 1,323 | BYYWPW6 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $386,818.24 | 2,117 | BYZR4X4 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $380,028.80 | 1,153 | BQ721R4 |
| 0.47% | TEM | TEMPUS AI INC-CL A | -- | $369,750.72 | 7,188 | BSLSJJ0 |
| 0.46% | PCVX | VAXCYTE INC | -- | $361,885.35 | 5,955 | BKPVGH6 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $348,476.31 | 42,549 | BNSP0B8 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $333,817.04 | 5,098 | BBBSBJ5 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $327,300.60 | 3,030 | BMVBZD3 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $325,225.56 | 4,884 | 2975098 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $324,864.48 | 1,212 | BD6JX35 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $294,373.09 | 3,377 | BMPRZV5 |
| 0.36% | ERAS | ERASCA INC | -- | $287,930.58 | 12,814 | BNLYBF3 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $287,133.00 | 2,541 | BLC89B2 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $271,019.42 | 2,641 | BDCBCD8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $244,195.66 | 3,494 | BRBCSP4 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $243,595.66 | 8,426 | BJRFSB7 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $242,788.52 | 6,718 | BLR6XK8 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $240,803.46 | 2,826 | BF2YWG4 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $234,852.16 | 3,424 | B17VCN9 |
| 0.29% | ALKS | ALKERMES PLC | -- | $233,877.27 | 6,897 | B3P6D26 |
| 0.29% | TERN | TERNS PHARMACEUTICALS INC | -- | $232,504.83 | 4,401 | BMDJ0C9 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $231,107.62 | 11,678 | BT18HP9 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $229,599.15 | 2,497 | BJDX8Y8 |
| 0.28% | SYRE | SPYRE THERAPEUTICS INC | -- | $224,960.76 | 3,249 | BQBBDY8 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $219,174.96 | 3,972 | BDHF4K6 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $216,572.60 | 5,290 | BYTQ6X1 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $200,508.04 | 4,223 | BFZQ0L8 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $200,241.72 | 2,268 | BM9HHL5 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $195,178.50 | 4,950 | BLB0YQ9 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $190,776.63 | 3,443 | BRJ3GY4 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $188,267.52 | 824 | 2501578 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,536.68 | 5,173 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $166,863.83 | 4,333 | BDD19F8 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $164,703.00 | 13,020 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $155,941.83 | 7,053 | 2713317 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $155,850.76 | 3,818 | BLFGJD5 |
| 0.19% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $151,686.52 | 3,226 | BQS9486 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $149,623.76 | 4,756 | BP8JSP4 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $149,361.30 | 2,538 | BGKG6G7 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $144,199.38 | 5,574 | BP2P6L0 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $138,629.97 | 4,439 | BKY5JZ8 |
| 0.17% | ALMS | ALUMIS INC | -- | $135,979.68 | 5,232 | BPLQG36 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $135,683.22 | 2,003 | BKVF0J2 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $128,746.80 | 6,812 | BN15WD1 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $127,630.90 | 6,562 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $127,154.56 | 4,216 | BK6L288 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $119,575.47 | 2,373 | B72ZBG4 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,226.08 | 5,128 | BKX9VD3 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $114,200.46 | 2,526 | BFXC933 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $113,365.67 | 2,953 | BL55460 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $111,620.73 | 7,397 | BN2R582 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $111,594.50 | 3,635 | BK0VHF6 |
| 0.14% | ADMA | ADMA BIOLOGICS INC | -- | $109,215.56 | 9,857 | B9NSBM2 |
| 0.14% | VCYT | VERACYTE INC | -- | $109,096.65 | 3,291 | BFTWZY0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $107,945.60 | 1,580 | BMGJZJ8 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $107,837.73 | 2,457 | BMFD115 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $107,368.17 | 1,761 | BMH5RL1 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $104,272.56 | 4,868 | BKS3RS7 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,095.72 | 3,999 | BJ62Z18 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $95,970.76 | 4,126 | BV2DHY6 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $93,333.24 | 3,276 | BP9N0G0 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,937.56 | 10,381 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,802.28 | 5,502 | BFWLC09 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $88,561.54 | 4,337 | B8DPDT7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $88,061.04 | 6,372 | BJ5FZ74 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $86,396.31 | 9,009 | BNZB1X8 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $85,005.57 | 3,099 | BPCQZY9 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $83,773.08 | 3,492 | BMX9K07 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $82,539.59 | 2,363 | BJQ05Z6 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $81,838.05 | 1,901 | BRXB0C0 |
| 0.10% | GRAL | GRAIL INC | -- | $81,597.15 | 1,611 | BSLSSX7 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $81,011.52 | 2,208 | BMVNDH9 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $78,754.04 | 4,547 | BPCK358 |
| 0.10% | NTLA | INTELLIA THERAPEUTICS INC | -- | $77,572.56 | 4,888 | BYZM6C2 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $76,799.52 | 2,394 | BKSGZN7 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $76,671.00 | 3,651 | BN7Q7R7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $75,603.50 | 21,601 | BM9FJ13 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $75,277.95 | 5,305 | BJH9ZN0 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $72,537.60 | 11,334 | BNC1BX1 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,439.68 | 928 | BCDWBX6 |
| 0.09% | PHVS | PHARVARIS NV | -- | $72,373.08 | 2,652 | BMZ2X38 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,308.80 | 2,102 | BSBMN89 |
| 0.09% | INBX | INHIBRX BIOSCIENCES INC | -- | $72,077.93 | 601 | BNSP8K3 |
| 0.09% | INVA | INNOVIVA INC | -- | $71,942.72 | 3,064 | BDDXF67 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $71,901.70 | 2,665 | BBC9WC7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,738.28 | 1,973 | BR3T9B6 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $71,693.10 | 15,030 | BWJDYK1 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $70,870.80 | 1,848 | BQKXDX4 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $70,521.92 | 4,256 | BMVLGP2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $67,306.05 | 6,503 | BK4PZ38 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $63,676.69 | 3,157 | BP7KZP7 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,393.76 | 2,424 | BCBVTX1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $62,005.23 | 1,857 | BQXJKH2 |
| 0.08% | ARDX | ARDELYX INC | -- | $60,482.08 | 10,148 | BN89V40 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $59,886.48 | 2,622 | BQB42F1 |
| 0.07% | HROW | HARROW INC | -- | $59,520.00 | 1,536 | BHNDW86 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $59,327.04 | 17,048 | BF0DMK7 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $59,286.31 | 4,709 | BYSS4X4 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $58,857.96 | 1,148 | BDRW1L7 |
| 0.07% | PGEN | PRECIGEN INC | -- | $57,994.20 | 14,645 | BKM5C84 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $56,952.21 | 7,791 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $54,931.00 | 6,740 | BJDQXG4 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $54,756.36 | 3,418 | BYP80F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $53,023.22 | 1,814 | BLCD809 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $53,010.00 | 1,710 | BMGTLY5 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $51,785.91 | 1,991 | BSRK699 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $50,900.60 | 3,316 | BMZ4LN0 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,811.30 | 12,546 | BL53SR3 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $48,304.08 | 2,568 | BP6C0S2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $47,402.00 | 3,425 | BMGS7L1 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $47,064.16 | 1,936 | BZ7PJQ1 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $46,650.57 | 853 | BL95N25 |
| 0.06% | SEPN | SEPTERNA INC | -- | $46,219.47 | 1,851 | BQNKXX2 |
| 0.06% | ALVO | ALVOTECH SA | -- | $46,204.60 | 13,670 | BPNTJ34 |
| 0.06% | QURE | UNIQURE NV | -- | $45,218.12 | 2,578 | BJFSR88 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $43,326.22 | 4,154 | BKVDFF7 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,427.28 | 1,673 | B3X26D8 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,415.92 | 1,314 | BX7RSN3 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $41,713.44 | 2,256 | BQB42H3 |
| 0.05% | SVRA | SAVARA INC | -- | $41,609.62 | 8,423 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,858.65 | 6,867 | BLR7H87 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,317.54 | 5,046 | B8K7T65 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,915.36 | 2,092 | BD06CS0 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,641.60 | 3,260 | BJLKVS6 |
| 0.05% | OMER | OMEROS CORP | -- | $39,640.64 | 2,932 | B4NB858 |
| 0.05% | GERN | GERON CORP | -- | $39,628.50 | 26,419 | 2370381 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,435.77 | 1,877 | BNFWZS4 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $38,248.42 | 2,518 | BMFX8Y7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,922.56 | 11,024 | BMFJJ97 |
| 0.05% | XNCR | XENCOR INC | -- | $37,810.65 | 3,037 | BGCYWN8 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $37,258.47 | 3,869 | BRXYZ57 |
| 0.05% | ANNX | ANNEXON INC | -- | $36,293.34 | 5,989 | BMVV9R5 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $35,721.60 | 3,904 | BMC3HS7 |
| 0.04% | MNKD | MANNKIND CORP | -- | $34,557.92 | 12,752 | BF081J4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,218.38 | 2,098 | BMNDK09 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,963.60 | 4,092 | BMCR7V2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,825.75 | 7,959 | BZ0QMB7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,557.50 | 2,165 | BQS7491 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,381.27 | 3,601 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,675.70 | 2,446 | BM90J52 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $31,198.95 | 7,011 | BYWVTY5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,044.92 | 3,331 | BFYQFJ2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,025.84 | 1,418 | BD9GVY0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,980.28 | 1,797 | BT9K6D8 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,109.68 | 2,356 | BMFK3H6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,138.70 | 1,230 | BKLCWZ3 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $28,684.80 | 7,470 | BPBJFM7 |
| 0.03% | ARVN | ARVINAS INC | -- | $27,592.16 | 2,648 | BDZ30Q0 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,525.94 | 3,227 | BQHN6C7 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,547.00 | 4,330 | BJQ0608 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,521.86 | 6,734 | B3MZ6K5 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $25,473.73 | 1,109 | BGL0JK3 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $25,161.02 | 1,721 | BRJJYT3 |
| 0.03% | ABSI | ABSCI CORP | -- | $24,705.31 | 6,223 | BN94K69 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,895.80 | 3,260 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,884.98 | 2,226 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,536.08 | 2,328 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,132.16 | 753 | BQD3J33 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,699.95 | 4,989 | BYV2W40 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,260.40 | 2,755 | BJDX8Z9 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,126.32 | 778 | BPBPCG8 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,857.35 | 9,301 | BFZNYB7 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $21,812.00 | 1,148 | BS2CR64 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $21,465.60 | 2,236 | BRCFFK6 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,303.04 | 3,026 | BP0TQC5 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,157.80 | 2,364 | BSMLR16 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,900.10 | 6,058 | BMCWKZ2 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $20,744.40 | 879 | BTNMG41 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,541.29 | 5,047 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,316.66 | 1,586 | BP81RK8 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,277.10 | 2,110 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $20,218.50 | 4,493 | BMXNGZ6 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,740.49 | 2,387 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,621.86 | 12,498 | B4N8MH9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,072.02 | 2,627 | BP81R42 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,893.72 | 9,892 | BBNBTD2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,834.05 | 2,095 | BZ0G875 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,156.21 | 3,021 | BQ6C357 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,835.12 | 3,231 | BLN9Z50 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,609.52 | 614 | B292NQ7 |
| 0.02% | IVVD | INVIVYD INC | -- | $17,315.17 | 11,467 | BM8NHS1 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,248.00 | 640 | BS2F741 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,537.92 | 4,494 | BDFKQ07 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,437.33 | 2,457 | B12W3P6 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $16,262.89 | 2,653 | BMVBZF5 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,046.70 | 1,202 | B9L5200 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,649.20 | 1,260 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,569.60 | 2,104 | B7F2TY6 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,424.91 | 6,917 | BN4JN37 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $15,233.12 | 1,943 | BL5B6Z1 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,973.09 | 5,181 | BFY7DC4 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,577.16 | 1,261 | BM7V485 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,241.42 | 2,682 | BDRJH21 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,431.45 | 2,965 | 2107437 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,968.40 | 4,040 | BZ8FPH3 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,703.59 | 8,303 | BFMLGR4 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,700.47 | 3,837 | BYTYP72 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,575.37 | 2,423 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,370.05 | 4,165 | BZC0D70 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,145.10 | 3,982 | BK5MWR1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,992.86 | 4,038 | BKX9NQ0 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $11,840.10 | 1,294 | BQV0J03 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,473.15 | 4,645 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,887.36 | 6,186 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,960.72 | 1,176 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,857.60 | 2,440 | BY7RB53 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $9,741.30 | 3,418 | BDDVW37 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,694.40 | 2,336 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,417.24 | 3,737 | B5LL2C2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,292.60 | 1,916 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $9,291.36 | 5,956 | BN13S71 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,739.42 | 3,867 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,616.16 | 1,548 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,606.63 | 8,087 | BNR5QT9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,537.08 | 1,284 | BP2NYN2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,306.70 | 2,357 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,971.17 | 3,071 | BPTK6Z2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,711.45 | 2,215 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,135.27 | 8,971 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,656.30 | 7,988 | BMYTJP4 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,838.37 | 901 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,526.73 | 2,847 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,406.67 | 2,577 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,695.87 | 4,037 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,577.97 | 9,577 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 35.67% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,357,610 | -- | 4,754 | -- |
| 29.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 23,657,190 | -- | 3,966 | -- |
| 27.77% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,082,430 | -- | 3,702 | -- |
| 19.80% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,741,635 | -- | 2,639 | -- |
| 16.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,128,965 | -- | 2,201 | -- |
| 4.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,775,845 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $27,304,523.01 | 27,304,523 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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