BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.67% | 24.99% | 47.98% | 51.34% | 69.14% | 43.98% | 6.41% | 12.60% | 18.47% | 04/07/2010 |
| BIB Market Price | 4.40% | 24.85% | 47.78% | 51.20% | 68.94% | 43.92% | 6.39% | 12.57% | 18.46% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -0.91% | 14.69% | 41.74% | 44.83% | 94.28% | 35.26% | 4.58% | 9.38% | 18.26% | 04/07/2010 |
| BIB NAV | -1.01% | 14.41% | 41.46% | 44.59% | 93.99% | 35.10% | 4.57% | 9.35% | 18.24% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $102,444,234
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/06/2026- NAV
- NAV Change
- Market Price $117.73
- Market Price Change $+5.07
- Trading Volume (M) 5,878
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $102,444,234
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/06/2026- NAV
- NAV Change
- Market Price $117.73
- Market Price Change $+5.07
- Trading Volume (M) 5,878
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2027. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2026
Holdings
as of 11/06/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.65% | GILD | GILEAD SCIENCES INC | -- | $5,849,494.50 | 35,050 | 2369174 |
| 5.30% | AMGN | AMGEN INC | -- | $5,493,731.44 | 11,932 | 2023607 |
| 4.97% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,153,040.71 | 9,419 | 2931034 |
| 4.11% | MRNA | MODERNA INC | -- | $4,260,732.78 | 16,762 | BGSXTS3 |
| 3.71% | REGN | REGENERON PHARMACEUTICALS | -- | $3,839,870.10 | 4,246 | 2730190 |
| 1.67% | RVMD | REVOLUTION MEDICINES INC | -- | $1,730,327.72 | 8,999 | BL71K91 |
| 1.49% | BIIB | BIOGEN INC | -- | $1,540,763.40 | 6,204 | 2455965 |
| 1.30% | ILMN | ILLUMINA INC | -- | $1,351,244.20 | 6,340 | 2613990 |
| 1.21% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $1,258,106.20 | 18,694 | BMVP7Y0 |
| 1.14% | ROIV | ROIVANT SCIENCES LTD | -- | $1,179,113.76 | 30,327 | BMW4NZ9 |
| 1.03% | ARGX | ARGENX SE - ADR | -- | $1,062,582.66 | 1,146 | BDVLM39 |
| 1.01% | INSM | INSMED INC | -- | $1,048,865.04 | 9,168 | 2614487 |
| 0.98% | INCY | INCYTE CORP | -- | $1,018,221.50 | 8,510 | 2471950 |
| 0.98% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,012,760.04 | 1,802 | 2430412 |
| 0.93% | VTRS | VIATRIS INC | -- | $960,139.84 | 48,224 | BMWS3X9 |
| 0.85% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $876,070.92 | 5,618 | B00FWN1 |
| 0.82% | GH | GUARDANT HEALTH INC | -- | $850,001.58 | 5,634 | BFXC911 |
| 0.74% | MEDP | MEDPACE HOLDINGS INC | -- | $765,444.92 | 1,172 | BDCBC61 |
| 0.70% | EXEL | EXELIXIS INC | -- | $723,736.71 | 10,403 | 2576941 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $702,476.21 | 4,267 | 2623911 |
| 0.64% | ASND | ASCENDIS PHARMA A/S | -- | $663,879.70 | 2,585 | BWXJHM8 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $639,721.00 | 2,725 | B4Q5ZN4 |
| 0.60% | BBIO | BRIDGEBIO PHARMA INC | -- | $625,373.22 | 8,418 | BK1KWG8 |
| 0.59% | ONC | BEONE MEDICINES LTD-ADR | -- | $612,474.80 | 1,505 | BYYWPW6 |
| 0.54% | TEM | TEMPUS AI INC-CL A | -- | $560,032.20 | 7,364 | BSLSJJ0 |
| 0.53% | SMMT | SUMMIT THERAPEUTICS INC | -- | $546,940.69 | 33,493 | BMTVQS7 |
| 0.48% | HALO | HALOZYME THERAPEUTICS INC | -- | $493,900.58 | 4,766 | 2975098 |
| 0.44% | KYMR | KYMERA THERAPEUTICS INC | -- | $459,737.70 | 3,490 | BMPRZV5 |
| 0.44% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $455,355.81 | 8,127 | 2437071 |
| 0.41% | SNY | SANOFI-ADR | -- | $425,759.04 | 9,051 | 2964557 |
| 0.41% | BNTX | BIONTECH SE-ADR | -- | $425,386.11 | 4,861 | BK6H543 |
| 0.39% | PCVX | VAXCYTE INC | -- | $399,184.72 | 6,248 | BKPVGH6 |
| 0.37% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $388,040.73 | 971 | BD59BS7 |
| 0.37% | SYRE | SPYRE THERAPEUTICS INC | -- | $384,489.72 | 3,702 | BQBBDY8 |
| 0.37% | IBRX | IMMUNITYBIO INC | -- | $384,222.96 | 44,496 | BNSP0B8 |
| 0.36% | KRYS | KRYSTAL BIOTECH INC | -- | $373,993.84 | 1,243 | BD6JX35 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $358,752.68 | 2,717 | BDCBCD8 |
| 0.33% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $344,946.96 | 5,931 | BYQBFJ8 |
| 0.32% | TWST | TWIST BIOSCIENCE CORP | -- | $336,520.94 | 2,786 | BGKG6G7 |
| 0.31% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $325,370.64 | 1,172 | BQ721R4 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $324,489.20 | 2,890 | BF2YWG4 |
| 0.31% | ALKS | ALKERMES PLC | -- | $323,319.60 | 7,044 | B3P6D26 |
| 0.30% | CYTK | CYTOKINETICS INC | -- | $313,388.53 | 5,837 | BBBSBJ5 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $299,328.72 | 11,864 | BT18HP9 |
| 0.29% | TXG | 10X GENOMICS INC-CLASS A | -- | $299,186.16 | 5,047 | BKS3RS7 |
| 0.28% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $294,507.22 | 14,623 | BFNF1D6 |
| 0.28% | AXSM | AXSOME THERAPEUTICS INC | -- | $291,214.00 | 2,200 | BYZR4X4 |
| 0.28% | ORKA | ORUKA THERAPEUTICS INC | -- | $285,950.80 | 2,780 | BKVF0J2 |
| 0.27% | CGON | CG ONCOLOGY INC | -- | $282,834.78 | 3,722 | BRBCSP4 |
| 0.27% | IONS | IONIS PHARMACEUTICALS INC | -- | $275,072.76 | 6,978 | BDJ0LS6 |
| 0.26% | IMVT | IMMUNOVANT INC | -- | $264,756.16 | 8,672 | BJRFSB7 |
| 0.25% | KOD | KODIAK SCIENCES INC | -- | $261,953.40 | 2,638 | BFXC933 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $256,289.40 | 837 | 2501578 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $255,574.44 | 2,727 | BJDX8Y8 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $240,004.22 | 5,113 | BFZQ0L8 |
| 0.22% | COGT | COGENT BIOSCIENCES INC | -- | $230,533.83 | 7,285 | BLR6XK8 |
| 0.22% | PTCT | PTC THERAPEUTICS INC | -- | $229,367.20 | 3,505 | B17VCN9 |
| 0.22% | SUPN | SUPERNUS INC | -- | $227,932.08 | 8,713 | BTZRLN8 |
| 0.22% | GRAL | GRAIL INC | -- | $227,821.44 | 1,876 | BSLSSX7 |
| 0.21% | GMAB | GENMAB A/S -SP ADR | -- | $218,327.73 | 4,071 | BBC9WC7 |
| 0.20% | ERAS | ERASCA INC | -- | $211,596.44 | 14,684 | BNLYBF3 |
| 0.20% | ABVX | ABIVAX SA-ADR | -- | $205,837.73 | 2,401 | BLC89B2 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $205,382.40 | 4,560 | BKY5JZ8 |
| 0.20% | CRSP | CRISPR THERAPEUTICS AG | -- | $203,284.20 | 4,060 | BDHF4K6 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $196,316.80 | 3,958 | BLFGJD5 |
| 0.18% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $190,348.08 | 2,028 | BRXB0C0 |
| 0.18% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $187,676.07 | 5,641 | BV2DHY6 |
| 0.18% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $187,466.00 | 6,700 | BJ5FZ74 |
| 0.17% | RLAY | RELAY THERAPEUTICS INC | -- | $171,120.00 | 9,200 | BN2R582 |
| 0.16% | ABCL | ABCELLERA BIOLOGICS INC | -- | $161,615.52 | 13,604 | BL53SR3 |
| 0.15% | XENE | XENON PHARMACEUTICALS INC | -- | $159,265.22 | 4,066 | BRJ3GY4 |
| 0.15% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $155,435.50 | 5,269 | BPCK358 |
| 0.15% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $153,556.59 | 7,233 | 2713317 |
| 0.15% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $152,896.68 | 19,017 | BF0DMK7 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $152,198.50 | 7,079 | BP2P6L0 |
| 0.15% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $152,046.68 | 3,076 | BMFD115 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $141,650.73 | 7,839 | BN15WD1 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $134,827.35 | 5,277 | BKX9VD3 |
| 0.13% | DNLI | DENALI THERAPEUTICS INC | -- | $134,689.77 | 6,711 | BD2B4V0 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $132,466.60 | 1,931 | BMH5RL1 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $127,202.92 | 1,612 | BMGJZJ8 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $126,584.48 | 4,052 | BK0VHF6 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $119,700.19 | 9,403 | B9NSBM2 |
| 0.11% | VCEL | VERICEL CORP | -- | $117,433.00 | 2,150 | BSBMN89 |
| 0.11% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $116,340.80 | 7,654 | BLR7H87 |
| 0.11% | BEAM | BEAM THERAPEUTICS INC | -- | $114,513.76 | 4,336 | BK6L288 |
| 0.11% | XNCR | XENCOR INC | -- | $111,611.50 | 3,122 | BGCYWN8 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $103,829.70 | 2,022 | BQXJKH2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $101,381.72 | 2,948 | BMZ2X38 |
| 0.09% | SEPN | SEPTERNA INC | -- | $95,746.00 | 1,960 | BQNKXX2 |
| 0.09% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $94,840.20 | 5,018 | BP8JSP4 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,929.10 | 5,585 | BFWLC09 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $90,487.80 | 3,867 | BMX9K07 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $90,099.63 | 3,025 | BL55460 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $88,267.77 | 2,979 | BPCQZY9 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $87,686.28 | 3,993 | BRXYZ57 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $86,739.84 | 7,104 | BK4PZ38 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $85,722.06 | 5,982 | BJH9ZN0 |
| 0.08% | REPL | REPLIMUNE GROUP INC | -- | $85,507.10 | 3,955 | BDDVW37 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $82,498.32 | 10,728 | 2100362 |
| 0.08% | VCYT | VERACYTE INC | -- | $81,515.84 | 3,374 | BFTWZY0 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $80,920.84 | 2,444 | BKSGZN7 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $79,731.08 | 2,332 | BSRK699 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,112.00 | 22,475 | BM9FJ13 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $79,013.88 | 4,434 | B8DPDT7 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $77,347.62 | 2,737 | BQB42H3 |
| 0.07% | NVAX | NOVAVAX INC | -- | $74,640.72 | 6,924 | BJDQXG4 |
| 0.07% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $73,730.87 | 2,507 | BCBVTX1 |
| 0.07% | ABSI | ABSCI CORP | -- | $73,264.68 | 7,204 | BN94K69 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $71,870.32 | 2,708 | BJQ05Z6 |
| 0.07% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $71,850.00 | 1,500 | BS2CR64 |
| 0.07% | PSNL | PERSONALIS INC | -- | $70,786.57 | 4,483 | BJQ0608 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $70,004.00 | 3,440 | BQS9486 |
| 0.07% | ALVO | ALVOTECH SA | -- | $69,007.14 | 14,199 | BPNTJ34 |
| 0.07% | ETON | ETON PHARMACEUTICALS INC | -- | $67,752.00 | 1,200 | BGL0JK3 |
| 0.06% | PGEN | PRECIGEN INC | -- | $67,188.57 | 15,031 | BKM5C84 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $66,760.70 | 5,882 | BYZM6C2 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $66,646.80 | 4,356 | BMVLGP2 |
| 0.06% | ANIP | ANI PHARMACEUTICALS INC | -- | $65,050.65 | 965 | BCDWBX6 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $64,912.64 | 4,888 | BYSS4X4 |
| 0.06% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $63,849.34 | 4,138 | BJ62Z18 |
| 0.06% | QURE | UNIQURE NV | -- | $63,190.40 | 2,912 | BJFSR88 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $60,983.82 | 1,674 | B3X26D8 |
| 0.06% | OCUL | OCULAR THERAPEUTIX INC | -- | $60,799.31 | 9,219 | BNZB1X8 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $60,275.55 | 1,945 | BLCD809 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,225.74 | 13,678 | BNC1BX1 |
| 0.06% | INVA | INNOVIVA INC | -- | $57,930.30 | 3,033 | BDDXF67 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $57,783.80 | 1,244 | BDRW1L7 |
| 0.05% | MLYS | MINERALYS THERAPEUTICS INC | -- | $56,889.63 | 3,711 | BP9N0G0 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $53,615.41 | 2,881 | BP6C0S2 |
| 0.05% | TYRA | TYRA BIOSCIENCES INC | -- | $52,980.75 | 2,505 | BMVNDH9 |
| 0.05% | MNKD | MANNKIND CORP | -- | $52,646.10 | 13,499 | BF081J4 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $52,148.84 | 617 | BNSP8K3 |
| 0.05% | OMER | OMEROS CORP | -- | $51,419.88 | 3,039 | B4NB858 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $50,854.65 | 1,785 | BNFWZS4 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $50,787.00 | 2,052 | BZ7PJQ1 |
| 0.05% | VOR | VOR BIOPHARMA INC | -- | $49,362.04 | 2,483 | BRJJYT3 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $49,222.16 | 2,014 | BR3T9B6 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $48,396.81 | 5,621 | BMC3HS7 |
| 0.05% | ZLAB | ZAI LAB LTD-ADR | -- | $47,647.60 | 1,870 | BD9GVY0 |
| 0.05% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $47,037.60 | 6,255 | BMCWKZ2 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $45,238.58 | 2,566 | BMFX8Y7 |
| 0.04% | HROW | HARROW INC | -- | $42,324.86 | 1,574 | BHNDW86 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $41,690.64 | 1,282 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $41,663.58 | 8,626 | BYXGN81 |
| 0.04% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $38,927.29 | 1,973 | BL5B6Z1 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $38,375.82 | 4,351 | BKVDFF7 |
| 0.04% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $37,851.17 | 3,581 | BP7KZP7 |
| 0.04% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $37,216.74 | 3,531 | BYP80F1 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $36,279.00 | 4,031 | BFYQFJ2 |
| 0.03% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $35,755.92 | 3,748 | BN7Q7R7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $35,405.10 | 7,614 | BPBJFM7 |
| 0.03% | ANNX | ANNEXON INC | -- | $33,427.80 | 7,959 | BMVV9R5 |
| 0.03% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $33,070.86 | 1,366 | BX7RSN3 |
| 0.03% | ALMS | ALUMIS INC | -- | $32,760.99 | 5,433 | BPLQG36 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,408.27 | 2,201 | BQS7491 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $31,085.60 | 784 | BQD3J33 |
| 0.03% | OABI | OMNIAB INC | -- | $30,698.09 | 6,103 | BN13S71 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,548.31 | 2,701 | BM90J52 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,449.04 | 6,936 | B3MZ6K5 |
| 0.03% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,358.43 | 8,306 | BZ0QMB7 |
| 0.03% | ARDX | ARDELYX INC | -- | $30,127.68 | 10,461 | BN89V40 |
| 0.03% | SANA | SANA BIOTECHNOLOGY INC | -- | $29,783.79 | 12,567 | BMFJJ97 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $29,661.59 | 4,501 | BQHN6C7 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $29,427.75 | 13,050 | B4N8MH9 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $29,169.60 | 885 | BL95N25 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $28,882.28 | 2,492 | BLFBZ32 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $28,555.68 | 4,353 | BP81R42 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $28,407.75 | 2,319 | BKLXFX5 |
| 0.03% | AVBP | ARRIVENT BIOPHARMA INC | -- | $28,234.80 | 2,070 | BMGTLY5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $28,096.25 | 3,211 | BP0TQC5 |
| 0.03% | WVE | WAVE LIFE SCIENCES INC | -- | $27,835.28 | 8,272 | C08GM13 |
| 0.03% | KURA | KURA ONCOLOGY INC | -- | $27,146.18 | 3,734 | BYZD465 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $26,923.09 | 3,673 | BMZ4LN0 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,821.67 | 2,627 | BMFK3H6 |
| 0.03% | GERN | GERON CORP | -- | $26,698.87 | 26,974 | 2370381 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $25,462.25 | 2,585 | BP2NYN2 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $24,098.10 | 6,179 | BYV2W40 |
| 0.02% | BCAX | BICARA THERAPEUTICS INC | -- | $24,021.05 | 2,777 | BQB42F1 |
| 0.02% | NGNE | NEUROGENE INC | -- | $21,235.09 | 839 | BS2F741 |
| 0.02% | RGNX | REGENXBIO INC | -- | $21,107.40 | 2,770 | BZ0G875 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $20,872.80 | 624 | B292NQ7 |
| 0.02% | CTMX | CYTOMX THERAPEUTICS INC | -- | $20,031.93 | 9,147 | BYWVTY5 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,021.09 | 5,269 | BYVQJ96 |
| 0.02% | EOLS | EVOLUS INC | -- | $18,856.66 | 2,771 | BDRJH21 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,869.50 | 2,166 | B7F2TY6 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $17,829.00 | 3,396 | BJLKVS6 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $17,603.74 | 2,254 | BP7L561 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,589.04 | 2,744 | BDZ30Q0 |
| 0.02% | KMDA | KAMADA LTD | -- | $17,503.83 | 2,421 | B2Q9833 |
| 0.02% | CRMD | CORMEDIX INC | -- | $17,401.72 | 3,271 | BJ0LT31 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $17,167.38 | 2,154 | B91XRN2 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,985.28 | 8,166 | BFY7DC4 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,924.80 | 820 | BPBPCG8 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,568.79 | 6,447 | BZ8FPH3 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $16,008.40 | 5,164 | BKX9NQ0 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $15,276.08 | 1,028 | BTNMG41 |
| 0.01% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,084.16 | 14,504 | BFZNYB7 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,511.77 | 3,367 | BLN9Z50 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $14,330.64 | 2,523 | BPRB2N7 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,442.00 | 1,222 | B9L5200 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,156.64 | 1,382 | BPRBTY7 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $12,668.48 | 2,596 | BSMLR16 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $12,337.20 | 1,192 | BKC9SX3 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $11,847.40 | 3,202 | BJDX8Z9 |
| 0.01% | SPRY | ARS PHARMACEUTICALS INC | -- | $11,648.25 | 4,175 | BMCR7V2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $11,108.16 | 8,352 | BNR5QT9 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,992.47 | 4,609 | BDFKQ07 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,778.88 | 8,421 | BFMLGR4 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $10,422.79 | 4,361 | BMXNGZ6 |
| 0.01% | BIOA | BIOAGE LABS INC | -- | $10,279.50 | 1,925 | BT9K6D8 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $10,099.68 | 1,588 | 2517058 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,991.20 | 2,715 | BMVBZF5 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $9,953.16 | 3,444 | BQ6C357 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,695.16 | 2,538 | B12W3P6 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,526.56 | 4,272 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $9,349.60 | 3,016 | 2107437 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $9,252.10 | 7,117 | BK5MWR1 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,990.26 | 1,634 | BP81RK8 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,787.52 | 832 | BM7V485 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $7,425.77 | 2,299 | BRCFFK6 |
| 0.01% | PEPG | PEPGEN INC | -- | $7,182.76 | 2,908 | BMTX3D7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,079.21 | 1,961 | BKDQKM6 |
| 0.01% | IVVD | INVIVYD INC | -- | $6,966.56 | 12,374 | BM8NHS1 |
| 0.01% | SION | SIONNA THERAPEUTICS INC | -- | $6,222.16 | 1,897 | BQKXDX4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,813.32 | 3,502 | BLBR8D5 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,743.80 | 3,191 | BPTK6Z2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,226.91 | 11,662 | BMYTJP4 |
| -- | CHRS | COHERUS ONCOLOGY INC | -- | $4,994.22 | 6,486 | BRK0149 |
| -- | CDXS | CODEXIS INC | -- | $4,963.68 | 4,596 | B5LL2C2 |
| -- | VYGR | VOYAGER THERAPEUTICS INC | -- | $4,822.89 | 2,586 | BY7RB53 |
| -- | FHTX | FOGHORN THERAPEUTICS INC | -- | $4,660.04 | 2,492 | BMF7DT9 |
| -- | LENZ | LENZ THERAPEUTICS INC | -- | $4,613.00 | 1,318 | BQV0J03 |
| -- | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $4,475.80 | 3,892 | BYTYP72 |
| -- | NBP | NOVABRIDGE BIOSCIENCES | -- | $4,285.56 | 4,712 | BKRRKY7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,183.09 | 2,411 | BKTV702 |
| -- | NMRA | NEUMORA THERAPEUTICS INC | -- | $3,970.03 | 7,888 | BN4JN37 |
| -- | TNYA | TENAYA THERAPEUTICS INC | -- | $3,390.20 | 9,412 | BNNXX52 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,649.25 | 4,845 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $2,501.12 | 256 | C0BCTT5 |
| -- | CRBU | CARIBOU BIOSCIENCES INC | -- | $2,018.70 | 4,499 | BNYJR68 |
| -- | EYPT | EYEPOINT INC | -- | $1,302.48 | 3,618 | BMGS7L1 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $1,074.06 | 918 | BTXQTX3 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | -- | COHERUS ONCOLOGY INC COMMON STOCK USD | -- | $00.00 | 5,356 | -- |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.55% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 36,834,115 | -- | 5,080 | -- |
| 32.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 33,774,273 | -- | 4,658 | -- |
| 28.43% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 29,452,790 | -- | 4,062 | -- |
| 18.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 19,134,888 | -- | 2,639 | -- |
| 17.59% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 18,221,286 | -- | 2,513 | -- |
| 4.40% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,560,759 | -- | 629 | -- |
| -- | IQMM | PROSHARES GENIUS MONEY MARKET ETF | -- | $17,022,100.00 | 170,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,402,806.01 | 21,402,806 | -- |
Index
as of 9/30/2026
- Total Number of Holdings245
- Price/Book Ratio6.08
- Dividend Yield ( % )0.49
- Avg. Index Market Capitalization$7.91 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: Why hedge?—A tool for managing risk
Periods of uncertainty often make investors want to reduce risk in their portfolios. A hedging strategy may help investors manage risk while remaining invested for long-term growth.
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