BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $81,001,330
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/02/2026- NAV
- NAV Change
- Market Price $81.77
- Market Price Change $-0.80
- Trading Volume (M) 3,167
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $81,001,330
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/02/2026- NAV
- NAV Change
- Market Price $81.77
- Market Price Change $-0.80
- Trading Volume (M) 3,167
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/02/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.33% | GILD | GILEAD SCIENCES INC | -- | $4,317,737.55 | 30,905 | 2369174 |
| 5.09% | AMGN | AMGEN INC | -- | $4,126,568.40 | 11,860 | 2023607 |
| 5.02% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,064,648.15 | 9,265 | 2931034 |
| 4.37% | REGN | REGENERON PHARMACEUTICALS | -- | $3,540,316.95 | 4,647 | 2730190 |
| 2.34% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,891,418.20 | 5,932 | B00FWN1 |
| 1.93% | INSM | INSMED INC | -- | $1,566,150.06 | 9,642 | 2614487 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,164,059.76 | 6,564 | 2455965 |
| 1.37% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,107,027.60 | 1,960 | 2430412 |
| 1.17% | ARGX | ARGENX SE - ADR | -- | $947,206.98 | 1,269 | BDVLM39 |
| 1.15% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $930,844.05 | 19,165 | BMVP7Y0 |
| 1.12% | ROIV | ROIVANT SCIENCES LTD | -- | $907,041.61 | 32,017 | BMW4NZ9 |
| 1.08% | RVMD | REVOLUTION MEDICINES INC | -- | $878,698.80 | 8,865 | BL71K91 |
| 1.08% | ILMN | ILLUMINA INC | -- | $871,406.58 | 6,841 | 2613990 |
| 1.07% | MRNA | MODERNA INC | -- | $869,216.40 | 17,667 | BGSXTS3 |
| 1.05% | INCY | INCYTE CORP | -- | $853,968.86 | 8,902 | 2471950 |
| 0.85% | VTRS | VIATRIS INC | -- | $692,254.08 | 51,507 | BMWS3X9 |
| 0.83% | SMMT | SUMMIT THERAPEUTICS INC | -- | $672,214.68 | 34,686 | BMTVQS7 |
| 0.78% | BBIO | BRIDGEBIO PHARMA INC | -- | $634,429.95 | 8,673 | BK1KWG8 |
| 0.78% | MEDP | MEDPACE HOLDINGS INC | -- | $632,393.46 | 1,269 | BDCBC61 |
| 0.78% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $631,354.50 | 2,754 | BV9G6B8 |
| 0.73% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $590,884.00 | 4,490 | 2623911 |
| 0.69% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $561,656.03 | 1,027 | BD59BS7 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $552,698.10 | 7,390 | BDJ0LS6 |
| 0.68% | GH | GUARDANT HEALTH INC | -- | $550,500.61 | 5,867 | BFXC911 |
| 0.65% | SNY | SANOFI-ADR | -- | $524,347.61 | 10,949 | 2964557 |
| 0.64% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $514,860.30 | 2,754 | B4Q5ZN4 |
| 0.63% | EXEL | EXELIXIS INC | -- | $509,753.96 | 11,617 | 2576941 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $477,522.00 | 8,604 | 2437071 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $464,653.28 | 5,096 | BK6H543 |
| 0.55% | ONC | BEONE MEDICINES LTD-ADR | -- | $444,429.70 | 1,430 | BYYWPW6 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $386,423.10 | 1,245 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $385,707.95 | 2,289 | BYZR4X4 |
| 0.47% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $382,352.95 | 6,265 | BYQBFJ8 |
| 0.46% | PCVX | VAXCYTE INC | -- | $375,850.44 | 6,438 | BKPVGH6 |
| 0.45% | TEM | TEMPUS AI INC-CL A | -- | $368,267.69 | 7,771 | BSLSJJ0 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $367,615.57 | 5,509 | BBBSBJ5 |
| 0.43% | NUVL | NUVALENT INC-A | -- | $345,177.82 | 3,274 | BMVBZD3 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $341,583.55 | 1,309 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $340,507.20 | 5,280 | 2975098 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $335,734.30 | 45,991 | BNSP0B8 |
| 0.40% | ABVX | ABIVAX SA-ADR | -- | $325,280.76 | 2,748 | BLC89B2 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $311,795.40 | 3,651 | BMPRZV5 |
| 0.37% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $296,291.90 | 2,855 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $263,615.95 | 3,055 | BF2YWG4 |
| 0.32% | ALKS | ALKERMES PLC | -- | $259,732.20 | 7,455 | B3P6D26 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $255,659.81 | 7,261 | BLR6XK8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $254,939.44 | 3,778 | BRBCSP4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $254,164.83 | 2,699 | BJDX8Y8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $250,952.31 | 3,703 | B17VCN9 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $250,789.04 | 4,757 | BMDJ0C9 |
| 0.30% | ERAS | ERASCA INC | -- | $246,668.50 | 13,850 | BNLYBF3 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $243,478.38 | 12,622 | BT18HP9 |
| 0.29% | APLS | APELLIS PHARMACEUTICALS INC | -- | $231,064.38 | 5,718 | BYTQ6X1 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $228,245.64 | 4,564 | BFZQ0L8 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $223,097.00 | 9,106 | BJRFSB7 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $212,546.43 | 4,293 | BDHF4K6 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $212,381.19 | 5,351 | BLB0YQ9 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $211,595.70 | 3,722 | BRJ3GY4 |
| 0.26% | APGE | APOGEE THERAPEUTICS INC | -- | $206,801.68 | 2,452 | BM9HHL5 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $186,377.80 | 3,485 | BQS9486 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $177,834.69 | 891 | 2501578 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $175,668.48 | 14,076 | BFNF1D6 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $174,385.32 | 4,684 | BDD19F8 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $170,449.18 | 5,594 | BTZRLN8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $169,634.58 | 5,142 | BP8JSP4 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $169,297.20 | 7,626 | 2713317 |
| 0.21% | SYRE | SPYRE THERAPEUTICS INC | -- | $167,148.54 | 3,513 | BQBBDY8 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $159,917.34 | 4,798 | BKY5JZ8 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $146,511.75 | 7,095 | BD2B4V0 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $138,756.60 | 7,365 | BN15WD1 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $137,675.82 | 2,742 | BGKG6G7 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $133,438.36 | 1,903 | BMH5RL1 |
| 0.16% | ALMS | ALUMIS INC | -- | $132,157.35 | 5,655 | BPLQG36 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $131,004.72 | 5,544 | BKX9VD3 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $130,425.12 | 3,192 | BL55460 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $130,320.75 | 6,025 | BP2P6L0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $129,481.20 | 2,565 | B72ZBG4 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $128,635.46 | 3,929 | BK0VHF6 |
| 0.16% | TVTX | TRAVERE THERAPEUTICS INC | -- | $125,625.88 | 4,127 | BLFGJD5 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $117,545.12 | 5,264 | BKS3RS7 |
| 0.14% | ORKA | ORUKA THERAPEUTICS INC | -- | $115,416.15 | 2,165 | BKVF0J2 |
| 0.14% | VCYT | VERACYTE INC | -- | $114,648.75 | 3,555 | BFTWZY0 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $112,375.62 | 4,557 | BK6L288 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $111,262.26 | 1,707 | BMGJZJ8 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $110,919.90 | 2,730 | BFXC933 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $108,902.24 | 4,688 | B8DPDT7 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $103,132.48 | 2,656 | BMFD115 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $102,011.28 | 6,888 | BJ5FZ74 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $101,204.40 | 11,220 | 2100362 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $100,257.30 | 7,995 | BN2R582 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $100,227.46 | 2,053 | BRXB0C0 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $99,216.75 | 3,945 | BN7Q7R7 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $99,120.45 | 4,621 | BLB0YH0 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $97,910.26 | 10,654 | B9NSBM2 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,051.35 | 4,323 | BJ62Z18 |
| 0.12% | GRAL | GRAIL INC | -- | $95,847.57 | 1,743 | BSLSSX7 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $95,473.80 | 3,540 | BP9N0G0 |
| 0.12% | TYRA | TYRA BIOSCIENCES INC | -- | $94,549.07 | 2,387 | BMVNDH9 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $92,848.28 | 5,948 | BFWLC09 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $92,259.20 | 2,621 | BCBVTX1 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $92,232.80 | 4,460 | BV2DHY6 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $86,378.40 | 3,348 | BPCQZY9 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $83,650.70 | 2,555 | BJQ05Z6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,684.11 | 9,739 | BNZB1X8 |
| 0.10% | PHVS | PHARVARIS NV | -- | $81,852.96 | 2,866 | BMZ2X38 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $80,858.53 | 1,997 | BQKXDX4 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $79,172.50 | 2,879 | BBC9WC7 |
| 0.10% | VCEL | VERICEL CORP | -- | $77,531.94 | 2,271 | BSBMN89 |
| 0.09% | INVA | INNOVIVA INC | -- | $76,165.87 | 3,313 | BDDXF67 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,432.63 | 1,003 | BCDWBX6 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $73,449.35 | 4,913 | BPCK358 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $72,615.39 | 23,349 | BM9FJ13 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,272.64 | 3,776 | BMX9K07 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $71,791.12 | 2,588 | BKSGZN7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,592.56 | 2,132 | BR3T9B6 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $71,523.20 | 1,240 | BDRW1L7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,346.00 | 4,600 | BMVLGP2 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,378.92 | 5,284 | BYZM6C2 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $68,487.84 | 5,736 | BJH9ZN0 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $66,276.91 | 2,009 | BQXJKH2 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,161.80 | 10,970 | BN89V40 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $63,700.86 | 7,031 | BK4PZ38 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $63,208.04 | 18,428 | BF0DMK7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $62,362.32 | 15,828 | BKM5C84 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $61,812.63 | 2,153 | BSRK699 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $61,579.92 | 16,248 | BWJDYK1 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $61,304.88 | 8,421 | BYZG9R0 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $60,845.98 | 2,834 | BQB42F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $60,457.63 | 1,961 | BLCD809 |
| 0.07% | HROW | HARROW INC | -- | $58,543.98 | 1,658 | BHNDW86 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,293.99 | 3,411 | BP7KZP7 |
| 0.07% | NVAX | NOVAVAX INC | -- | $56,117.60 | 7,288 | BJDQXG4 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $54,264.86 | 3,694 | BYP80F1 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $53,990.10 | 3,585 | BMZ4LN0 |
| 0.07% | ALVO | ALVOTECH SA | -- | $53,932.40 | 14,776 | BPNTJ34 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $53,699.50 | 5,090 | BYSS4X4 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $53,545.61 | 12,253 | BNC1BX1 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $52,255.10 | 2,435 | BQB42H3 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $51,244.96 | 923 | BL95N25 |
| 0.06% | SVRA | SAVARA INC | -- | $50,612.68 | 9,103 | BYXGN81 |
| 0.06% | SEPN | SEPTERNA INC | -- | $50,435.54 | 2,003 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $49,633.60 | 3,704 | BMGS7L1 |
| 0.06% | QURE | UNIQURE NV | -- | $47,824.92 | 2,787 | BJFSR88 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,738.24 | 13,562 | BL53SR3 |
| 0.06% | GERN | GERON CORP | -- | $47,402.96 | 28,556 | 2370381 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,971.83 | 1,847 | BMGTLY5 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $45,912.51 | 1,421 | BX7RSN3 |
| 0.06% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $44,993.90 | 2,261 | BD06CS0 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $44,965.68 | 5,457 | B8K7T65 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,828.88 | 7,422 | BLR7H87 |
| 0.05% | XNCR | XENCOR INC | -- | $42,029.61 | 3,281 | BGCYWN8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,493.05 | 2,029 | BNFWZS4 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $41,358.03 | 651 | BNSP8K3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,087.00 | 1,810 | B3X26D8 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $40,431.75 | 2,775 | BP6C0S2 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $40,394.48 | 2,722 | BMFX8Y7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,962.16 | 3,524 | BJLKVS6 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,916.10 | 4,490 | BKVDFF7 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,529.35 | 4,183 | BRXYZ57 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $39,390.26 | 2,093 | BZ7PJQ1 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,545.92 | 8,604 | BZ0QMB7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $38,138.49 | 2,643 | BM90J52 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $38,131.20 | 11,916 | BMFJJ97 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,710.90 | 4,423 | BMCR7V2 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $36,317.34 | 2,267 | BMNDK09 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,612.50 | 6,475 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,685.02 | 2,342 | BQS7491 |
| 0.04% | OMER | OMEROS CORP | -- | $34,563.90 | 3,171 | B4NB858 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $34,560.24 | 7,579 | BYWVTY5 |
| 0.04% | MNKD | MANNKIND CORP | -- | $34,457.50 | 13,783 | BF081J4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $34,020.00 | 1,944 | BT9K6D8 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $33,536.90 | 1,858 | BRJJYT3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,510.12 | 3,892 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $33,048.00 | 3,600 | BFYQFJ2 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,037.20 | 1,330 | BKLCWZ3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,288.53 | 1,533 | BD9GVY0 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $31,066.54 | 3,694 | BDDVW37 |
| 0.04% | ARVN | ARVINAS INC | -- | $31,052.70 | 2,862 | BDZ30Q0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $30,800.98 | 4,681 | BJQ0608 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $29,963.01 | 1,199 | BGL0JK3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $28,614.04 | 2,548 | BMFK3H6 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,911.34 | 10,694 | BBNBTD2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $26,809.00 | 8,075 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,110.14 | 3,486 | BQHN6C7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,778.28 | 7,282 | B3MZ6K5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,636.80 | 840 | BPBPCG8 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $24,931.44 | 10,053 | BFZNYB7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,844.20 | 3,524 | BJ0LT31 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $24,433.80 | 4,220 | BMC3HS7 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $23,951.16 | 2,979 | BJDX8Z9 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,742.88 | 2,408 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,659.80 | 2,517 | BLFBZ32 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $23,265.03 | 4,857 | BMXNGZ6 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $22,971.00 | 2,418 | BRCFFK6 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,671.72 | 2,556 | BSMLR16 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,659.00 | 5,395 | BYV2W40 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,541.54 | 5,458 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,525.95 | 1,713 | BP81RK8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,381.89 | 813 | BQD3J33 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,861.07 | 2,581 | B2Q9833 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,633.36 | 2,282 | BKLXFX5 |
| 0.03% | ABSI | ABSCI CORP | -- | $20,581.56 | 6,726 | BN94K69 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $20,170.71 | 951 | BTNMG41 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $20,131.20 | 3,495 | BLN9Z50 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,534.88 | 664 | B292NQ7 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $19,319.55 | 6,549 | BMCWKZ2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,311.92 | 2,264 | BZ0G875 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,710.68 | 5,602 | BFY7DC4 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,675.80 | 3,265 | BQ6C357 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,580.14 | 2,841 | BP81R42 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,578.00 | 2,654 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,305.28 | 1,362 | BPRBTY7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,102.06 | 13,509 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,245.90 | 4,858 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,068.86 | 1,299 | B9L5200 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,788.96 | 3,204 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $16,356.00 | 1,363 | BM7V485 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,350.00 | 3,270 | BP0TQC5 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,866.88 | 12,396 | BM8NHS1 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,704.40 | 2,276 | B7F2TY6 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,641.50 | 2,870 | BMVBZF5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,950.00 | 7,475 | BN4JN37 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,317.48 | 692 | BS2F741 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,528.33 | 1,399 | BQV0J03 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,916.60 | 2,620 | BMF7DT9 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,745.76 | 4,306 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,651.93 | 8,973 | BFMLGR4 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $12,474.00 | 2,100 | BL5B6Z1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,422.76 | 4,501 | BZC0D70 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,396.54 | 4,146 | BYTYP72 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,306.48 | 4,364 | BKX9NQ0 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,201.03 | 5,021 | BKRRKY7 |
| 0.01% | EOLS | EVOLUS INC | -- | $11,682.97 | 2,899 | BDRJH21 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,657.22 | 4,366 | BZ8FPH3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,568.51 | 6,687 | BRK0149 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,781.75 | 2,525 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,468.65 | 2,073 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,442.52 | 2,637 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,206.13 | 1,271 | BKC9SX3 |
| 0.01% | OABI | OMNIAB INC | -- | $9,916.06 | 6,439 | BN13S71 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,134.00 | 3,320 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,111.14 | 4,181 | BNYJR68 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,565.04 | 2,394 | BP7L561 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,373.52 | 1,386 | BP2NYN2 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,354.62 | 4,041 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,734.84 | 9,696 | BNNXX52 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,537.27 | 8,742 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,432.00 | 1,675 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,092.11 | 2,549 | BKTV702 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,545.84 | 8,633 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,321.48 | 3,076 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,183.90 | 973 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,123.28 | 2,786 | BLBR8D5 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,830.98 | 10,354 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,664.05 | 4,363 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $23.78 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.41% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,677,250 | -- | 4,900 | -- |
| 30.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,066,258 | -- | 4,283 | -- |
| 26.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,665,955 | -- | 3,702 | -- |
| 19.07% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,444,748 | -- | 2,639 | -- |
| 14.38% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,646,475 | -- | 1,990 | -- |
| 4.57% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,704,633 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,530,140.15 | 25,530,140 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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