BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 5/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 3.79% | -3.99% | 1.49% | 6.15% | 98.53% | 18.55% | 0.58% | -- | 16.40% | 04/07/2010 |
| BIB Market Price | 3.64% | -4.03% | 1.26% | 6.04% | 98.32% | 18.49% | 0.55% | -- | 16.40% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,860,852
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 7/13/2026- NAV
- NAV Change
- Market Price $99.88
- Market Price Change $-3.04
- Trading Volume (M) 16,136
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,860,852
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 7/13/2026- NAV
- NAV Change
- Market Price $99.88
- Market Price Change $-3.04
- Trading Volume (M) 16,136
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 7/13/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.49% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,765,640.25 | 7,841 | 2931034 |
| 4.48% | AMGN | AMGEN INC | -- | $3,754,807.65 | 10,417 | 2023607 |
| 4.09% | GILD | GILEAD SCIENCES INC | -- | $3,429,671.40 | 26,101 | 2369174 |
| 2.73% | REGN | REGENERON PHARMACEUTICALS | -- | $2,285,671.23 | 3,447 | 2730190 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,308,620.30 | 7,114 | BL71K91 |
| 1.53% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,286,764.02 | 4,467 | B00FWN1 |
| 1.23% | BIIB | BIOGEN INC | -- | $1,032,817.23 | 4,941 | 2455965 |
| 1.15% | ILMN | ILLUMINA INC | -- | $962,603.25 | 5,065 | 2613990 |
| 1.06% | MRNA | MODERNA INC | -- | $890,160.84 | 13,284 | BGSXTS3 |
| 1.00% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $837,774.45 | 14,841 | BMVP7Y0 |
| 0.99% | ROIV | ROIVANT SCIENCES LTD | -- | $830,655.70 | 24,070 | BMW4NZ9 |
| 0.97% | ARGX | ARGENX SE - ADR | -- | $810,531.25 | 925 | BDVLM39 |
| 0.94% | INSM | INSMED INC | -- | $791,810.70 | 7,255 | 2614487 |
| 0.91% | INCY | INCYTE CORP | -- | $763,856.01 | 6,687 | 2471950 |
| 0.91% | UTHR | UNITED THERAPEUTICS CORP | -- | $761,044.97 | 1,421 | 2430412 |
| 0.84% | GH | GUARDANT HEALTH INC | -- | $703,137.60 | 4,439 | BFXC911 |
| 0.76% | VTRS | VIATRIS INC | -- | $638,767.47 | 38,973 | BMWS3X9 |
| 0.70% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $586,020.60 | 3,366 | 2623911 |
| 0.65% | ASND | ASCENDIS PHARMA A/S | -- | $547,148.86 | 2,063 | BWXJHM8 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $544,423.24 | 6,553 | BK1KWG8 |
| 0.60% | MEDP | MEDPACE HOLDINGS INC | -- | $505,801.26 | 954 | BDCBC61 |
| 0.59% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $497,637.00 | 2,100 | B4Q5ZN4 |
| 0.56% | EXEL | EXELIXIS INC | -- | $471,464.52 | 8,413 | 2576941 |
| 0.49% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $410,463.00 | 773 | BD59BS7 |
| 0.47% | SMMT | SUMMIT THERAPEUTICS INC | -- | $397,417.50 | 25,975 | BMTVQS7 |
| 0.47% | AXSM | AXSOME THERAPEUTICS INC | -- | $392,641.60 | 1,720 | BYZR4X4 |
| 0.46% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $382,787.20 | 6,466 | 2437071 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $373,205.12 | 4,538 | BBBSBJ5 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $359,442.16 | 989 | BD6JX35 |
| 0.42% | BNTX | BIONTECH SE-ADR | -- | $350,372.30 | 3,890 | BK6H543 |
| 0.42% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $349,132.21 | 4,711 | BYQBFJ8 |
| 0.41% | SNY | SANOFI-ADR | -- | $342,584.00 | 7,786 | 2964557 |
| 0.40% | ONC | BEONE MEDICINES LTD-ADR | -- | $335,267.88 | 1,103 | BYYWPW6 |
| 0.39% | TEM | TEMPUS AI INC-CL A | -- | $326,575.27 | 5,839 | BSLSJJ0 |
| 0.37% | IONS | IONIS PHARMACEUTICALS INC | -- | $313,770.75 | 5,529 | BDJ0LS6 |
| 0.36% | NUVL | NUVALENT INC-A | -- | $305,388.16 | 2,464 | BMVBZD3 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $304,041.60 | 2,754 | BMPRZV5 |
| 0.36% | HALO | HALOZYME THERAPEUTICS INC | -- | $302,080.59 | 3,969 | 2975098 |
| 0.35% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $295,355.10 | 3,530 | BDD19F8 |
| 0.35% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $294,113.60 | 935 | BQ721R4 |
| 0.34% | ALKS | ALKERMES PLC | -- | $289,227.12 | 5,576 | B3P6D26 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $279,653.17 | 2,153 | BDCBCD8 |
| 0.33% | APGE | APOGEE THERAPEUTICS INC | -- | $277,007.40 | 2,070 | BM9HHL5 |
| 0.33% | PCVX | VAXCYTE INC | -- | $275,511.93 | 4,831 | BKPVGH6 |
| 0.33% | IBRX | IMMUNITYBIO INC | -- | $273,047.29 | 35,051 | BNSP0B8 |
| 0.33% | SYRE | SPYRE THERAPEUTICS INC | -- | $272,660.57 | 2,909 | BQBBDY8 |
| 0.32% | IMVT | IMMUNOVANT INC | -- | $265,907.70 | 6,871 | BJRFSB7 |
| 0.31% | ABVX | ABIVAX SA-ADR | -- | $263,801.20 | 1,940 | BLC89B2 |
| 0.29% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $246,689.55 | 2,295 | BF2YWG4 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $242,960.64 | 2,041 | BJDX8Y8 |
| 0.27% | PTCT | PTC THERAPEUTICS INC | -- | $225,528.09 | 2,773 | B17VCN9 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $219,292.30 | 4,009 | BFZQ0L8 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $218,871.04 | 3,232 | BRJ3GY4 |
| 0.26% | COGT | COGENT BIOSCIENCES INC | -- | $214,233.74 | 5,719 | BLR6XK8 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $214,020.00 | 2,952 | BRBCSP4 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $207,816.00 | 672 | 2501578 |
| 0.22% | TWST | TWIST BIOSCIENCE CORP | -- | $188,199.05 | 2,083 | BGKG6G7 |
| 0.22% | ERAS | ERASCA INC | -- | $186,321.10 | 10,409 | BNLYBF3 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $183,379.32 | 10,674 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $175,230.77 | 3,113 | BLFGJD5 |
| 0.20% | ORKA | ORUKA THERAPEUTICS INC | -- | $170,557.52 | 2,017 | BKVF0J2 |
| 0.20% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $164,056.80 | 4,080 | BTZRLN8 |
| 0.20% | TXG | 10X GENOMICS INC-CLASS A | -- | $163,780.17 | 3,921 | BKS3RS7 |
| 0.19% | CRSP | CRISPR THERAPEUTICS AG | -- | $163,484.27 | 3,229 | BDHF4K6 |
| 0.19% | CAI | CARIS LIFE SCIENCES INC | -- | $161,370.54 | 9,459 | BT18HP9 |
| 0.19% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $159,191.55 | 3,647 | BV2DHY6 |
| 0.18% | VCYT | VERACYTE INC | -- | $153,644.04 | 2,673 | BFTWZY0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $148,572.00 | 3,600 | BKY5JZ8 |
| 0.17% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $146,089.50 | 5,729 | 2713317 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $140,661.76 | 5,312 | BD2B4V0 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $137,319.12 | 4,842 | BP2P6L0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $134,832.04 | 2,611 | BQS9486 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $134,462.67 | 7,179 | BN2R582 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $130,752.84 | 5,531 | BN15WD1 |
| 0.16% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $130,158.08 | 3,911 | BP8JSP4 |
| 0.14% | ALMS | ALUMIS INC | -- | $116,109.20 | 4,132 | BPLQG36 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $113,524.32 | 4,186 | BKX9VD3 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $112,604.14 | 5,357 | BJ5FZ74 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $109,426.68 | 3,294 | BJ62Z18 |
| 0.13% | BEAM | BEAM THERAPEUTICS INC | -- | $106,516.00 | 3,436 | BK6L288 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $106,208.70 | 2,938 | BK0VHF6 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $103,673.06 | 2,038 | BMFD115 |
| 0.12% | GRAL | GRAIL INC | -- | $103,176.60 | 1,437 | BSLSSX7 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $99,683.00 | 2,402 | BL55460 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $97,178.42 | 1,279 | BMGJZJ8 |
| 0.11% | MBX | MBX BIOSCIENCES INC | -- | $95,463.60 | 1,590 | BQXJKH2 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,517.94 | 1,551 | BRXB0C0 |
| 0.11% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $92,001.05 | 1,943 | B72ZBG4 |
| 0.10% | QURE | UNIQURE NV | -- | $86,967.60 | 2,116 | BJFSR88 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $86,063.40 | 2,094 | BFXC933 |
| 0.10% | TARS | TARSUS PHARMACEUTICALS INC | -- | $85,465.71 | 1,441 | BMH5RL1 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $84,294.46 | 8,506 | 2100362 |
| 0.10% | PHVS | PHARVARIS NV | -- | $81,958.59 | 2,337 | BMZ2X38 |
| 0.10% | VCEL | VERICEL CORP | -- | $81,017.94 | 1,706 | BSBMN89 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $80,694.50 | 1,990 | BCBVTX1 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $78,531.18 | 3,458 | BMVLGP2 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $78,519.56 | 4,753 | BJH9ZN0 |
| 0.09% | MLYS | MINERALYS THERAPEUTICS INC | -- | $76,203.58 | 2,762 | BP9N0G0 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $73,094.40 | 2,538 | BBC9WC7 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,718.00 | 2,824 | BMX9K07 |
| 0.09% | OCUL | OCULAR THERAPEUTIX INC | -- | $72,390.76 | 7,327 | BNZB1X8 |
| 0.08% | ADMA | ADMA BIOLOGICS INC | -- | $69,580.29 | 7,757 | B9NSBM2 |
| 0.08% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $68,864.88 | 4,296 | BFWLC09 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,840.98 | 1,937 | BKSGZN7 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $68,134.56 | 976 | BDRW1L7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $67,914.63 | 2,967 | BN7Q7R7 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $66,614.84 | 10,217 | BL53SR3 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $66,472.24 | 3,532 | B8DPDT7 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $66,276.60 | 1,508 | BQKXDX4 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,025.18 | 1,602 | BR3T9B6 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $65,013.30 | 1,990 | BMVNDH9 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $64,782.61 | 3,721 | BPCK358 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $64,440.81 | 1,631 | BZ7PJQ1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $62,364.84 | 3,876 | BYSS4X4 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $62,093.50 | 2,825 | BP7KZP7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $61,901.85 | 2,199 | BQB42F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $61,693.61 | 11,933 | BKM5C84 |
| 0.07% | ANIP | ANI PHARMACEUTICALS INC | -- | $61,620.80 | 760 | BCDWBX6 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $61,394.64 | 2,084 | BJQ05Z6 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $61,235.37 | 12,321 | BWJDYK1 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $60,903.48 | 2,442 | BPCQZY9 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $60,816.42 | 4,671 | BYZM6C2 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,369.72 | 14,943 | BF0DMK7 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $58,994.08 | 2,116 | BQB42H3 |
| 0.07% | CMPS | COMPASS PATHWAYS PLC | -- | $58,765.55 | 4,457 | BMC3HS7 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $58,026.15 | 2,289 | BP6C0S2 |
| 0.07% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $57,938.10 | 17,557 | BM9FJ13 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $56,544.76 | 3,166 | BRXYZ57 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,849.96 | 5,643 | BK4PZ38 |
| 0.07% | INVA | INNOVIVA INC | -- | $54,814.28 | 2,468 | BDDXF67 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $54,070.54 | 1,853 | BSRK699 |
| 0.06% | ABSI | ABSCI CORP | -- | $53,326.83 | 5,223 | BN94K69 |
| 0.06% | PSNL | PERSONALIS INC | -- | $52,700.16 | 3,504 | BJQ0608 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,343.84 | 1,556 | BMGTLY5 |
| 0.06% | HROW | HARROW INC | -- | $52,053.45 | 1,245 | BHNDW86 |
| 0.06% | SEPN | SEPTERNA INC | -- | $51,746.16 | 1,506 | BQNKXX2 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $51,734.08 | 9,616 | BNC1BX1 |
| 0.06% | NVAX | NOVAVAX INC | -- | $49,031.73 | 5,503 | BJDQXG4 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $48,377.61 | 1,489 | BLCD809 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $47,172.96 | 5,781 | BLR7H87 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $45,068.69 | 489 | BNSP8K3 |
| 0.05% | ARDX | ARDELYX INC | -- | $42,502.66 | 8,269 | BN89V40 |
| 0.05% | MNKD | MANNKIND CORP | -- | $41,773.60 | 10,340 | BF081J4 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $41,423.36 | 2,816 | BYP80F1 |
| 0.05% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $40,891.68 | 1,168 | BS2CR64 |
| 0.05% | EYPT | EYEPOINT INC | -- | $40,083.96 | 2,807 | BMGS7L1 |
| 0.05% | SVRA | SAVARA INC | -- | $39,353.44 | 6,856 | BYXGN81 |
| 0.05% | WVE | WAVE LIFE SCIENCES LTD | -- | $38,323.95 | 6,441 | BYZG9R0 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $38,241.66 | 3,099 | BFYQFJ2 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $37,849.34 | 1,087 | BX7RSN3 |
| 0.04% | XNCR | XENCOR INC | -- | $37,100.80 | 2,480 | BGCYWN8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,776.46 | 2,058 | BM90J52 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $36,243.90 | 3,465 | BKVDFF7 |
| 0.04% | ALVO | ALVOTECH SA | -- | $35,300.72 | 10,444 | BPNTJ34 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $34,744.20 | 2,932 | BMZ4LN0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $34,203.44 | 916 | BGL0JK3 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $33,899.32 | 9,313 | BMFJJ97 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,636.18 | 1,317 | B3X26D8 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $32,941.74 | 2,041 | BMFX8Y7 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $32,706.42 | 1,814 | BRJJYT3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,437.87 | 1,489 | BT9K6D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,435.43 | 2,973 | BYZD465 |
| 0.04% | SLDB | SOLID BIOSCIENCES INC | -- | $31,998.24 | 3,292 | BQHN6C7 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $31,399.32 | 4,937 | BMCWKZ2 |
| 0.04% | ANNX | ANNEXON INC | -- | $30,863.66 | 5,482 | BMVV9R5 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,830.99 | 6,609 | BZ0QMB7 |
| 0.04% | GERN | GERON CORP | -- | $30,481.72 | 21,466 | 2370381 |
| 0.04% | GRFS | GRIFOLS SA-ADR | -- | $29,397.60 | 4,083 | B8K7T65 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,153.97 | 2,671 | BJLKVS6 |
| 0.03% | TBPH | THERAVANCE BIOPHARMA INC | -- | $29,152.50 | 1,725 | BMNDK09 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $28,956.95 | 2,090 | BMFK3H6 |
| 0.03% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $28,472.04 | 1,476 | BNFWZS4 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,401.22 | 1,751 | BQS7491 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $27,470.28 | 2,765 | BDDVW37 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $26,958.20 | 7,286 | BYWVTY5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,070.04 | 1,978 | BLFBZ32 |
| 0.03% | SPRY | ARS PHARMACEUTICALS INC | -- | $25,727.76 | 3,324 | BMCR7V2 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $25,696.00 | 4,672 | BYV2W40 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $25,564.70 | 619 | BQD3J33 |
| 0.03% | OMER | OMEROS CORP | -- | $24,224.20 | 2,420 | B4NB858 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $24,220.00 | 3,460 | BP81R42 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,637.28 | 2,452 | BP0TQC5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,393.64 | 1,018 | BKLCWZ3 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,232.00 | 704 | BL95N25 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,192.89 | 5,509 | B3MZ6K5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,291.50 | 11,550 | BFZNYB7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $22,057.50 | 1,730 | BZ0G875 |
| 0.03% | CRMD | CORMEDIX INC | -- | $21,823.36 | 2,623 | BJ0LT31 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,771.56 | 634 | BPBPCG8 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,582.00 | 1,100 | BD9GVY0 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $21,241.15 | 6,043 | BPBJFM7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $20,347.92 | 531 | BS2F741 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,786.30 | 1,751 | BKLXFX5 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $19,530.68 | 6,532 | BFY7DC4 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,512.20 | 2,162 | BDZ30Q0 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,056.06 | 4,201 | BYVQJ96 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,229.76 | 5,136 | BZ8FPH3 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,965.04 | 1,092 | BPRBTY7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $15,804.18 | 2,034 | BSMLR16 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,546.66 | 10,434 | B4N8MH9 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $15,478.99 | 1,753 | B91XRN2 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $15,088.61 | 5,457 | BK5MWR1 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $14,959.60 | 502 | B292NQ7 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $14,643.20 | 2,048 | BP2NYN2 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,603.88 | 1,572 | BL5B6Z1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $14,500.08 | 3,699 | BKX9NQ0 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,370.08 | 2,204 | BDRJH21 |
| 0.02% | KMDA | KAMADA LTD | -- | $13,838.10 | 1,930 | B2Q9833 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,776.40 | 1,705 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $13,592.88 | 3,654 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,285.36 | 974 | B9L5200 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $13,249.60 | 1,820 | BRCFFK6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,955.55 | 3,478 | BMXNGZ6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,684.24 | 2,676 | BLN9Z50 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,197.77 | 2,626 | BQ6C357 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,066.00 | 2,011 | B12W3P6 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $11,220.39 | 783 | BTNMG41 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $11,161.08 | 2,163 | BMVBZF5 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,684.16 | 1,964 | BMF7DT9 |
| 0.01% | OABI | OMNIAB INC | -- | $10,239.83 | 4,853 | BN13S71 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $9,932.28 | 6,711 | BFMLGR4 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,918.40 | 6,199 | BN4JN37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,710.95 | 1,795 | BP7L561 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $8,664.00 | 2,400 | 2107437 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,553.60 | 1,296 | BP81RK8 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,344.70 | 3,406 | BZC0D70 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $7,890.66 | 2,229 | BJDX8Z9 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,762.39 | 9,857 | BM8NHS1 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $7,659.10 | 2,005 | BPRB2N7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,591.08 | 5,164 | BRK0149 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,348.20 | 662 | BM7V485 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $7,289.70 | 3,102 | BYTYP72 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,986.16 | 3,756 | BKRRKY7 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,853.50 | 3,046 | B5LL2C2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,777.30 | 1,558 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,548.04 | 2,021 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $6,367.79 | 949 | BKC9SX3 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,072.15 | 7,259 | BNNXX52 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,976.00 | 3,320 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $5,801.39 | 1,253 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $5,755.64 | 6,621 | BNR5QT9 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,655.92 | 2,318 | BMTX3D7 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,620.03 | 2,543 | BPTK6Z2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $5,475.81 | 1,047 | BQV0J03 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,170.36 | 2,119 | BLBR8D5 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,135.62 | 7,430 | BMYTJP4 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,362.72 | 732 | BTXQTX3 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,642.30 | 1,917 | BKTV702 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,379.21 | 3,761 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,131.76 | 7,854 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.47% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,903,239 | -- | 4,415 | -- |
| 32.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 27,011,272 | -- | 4,126 | -- |
| 30.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 25,990,002 | -- | 3,970 | -- |
| 20.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 17,276,477 | -- | 2,639 | -- |
| 19.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 16,451,606 | -- | 2,513 | -- |
| 4.94% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,143,998 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,007,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $31,141,072.49 | 31,141,072 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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