BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $78,412,893
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 3/26/2026- NAV
- NAV Change
- Market Price $78.41
- Market Price Change $-0.32
- Trading Volume (M) 3,860
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $78,412,893
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 3/26/2026- NAV
- NAV Change
- Market Price $78.41
- Market Price Change $-0.32
- Trading Volume (M) 3,860
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/26/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.45% | GILD | GILEAD SCIENCES INC | -- | $4,230,276.40 | 30,905 | 2369174 |
| 5.42% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,203,901.10 | 9,265 | 2931034 |
| 5.40% | AMGN | AMGEN INC | -- | $4,188,477.60 | 11,860 | 2023607 |
| 4.53% | REGN | REGENERON PHARMACEUTICALS | -- | $3,516,524.31 | 4,647 | 2730190 |
| 2.51% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,946,645.12 | 5,932 | B00FWN1 |
| 1.83% | INSM | INSMED INC | -- | $1,423,159.20 | 9,642 | 2614487 |
| 1.62% | BIIB | BIOGEN INC | -- | $1,254,117.84 | 6,564 | 2455965 |
| 1.34% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,043,758.80 | 1,960 | 2430412 |
| 1.22% | MRNA | MODERNA INC | -- | $946,421.19 | 17,667 | BGSXTS3 |
| 1.16% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $899,605.10 | 19,165 | BMVP7Y0 |
| 1.13% | ARGX | ARGENX SE - ADR | -- | $879,201.27 | 1,269 | BDVLM39 |
| 1.13% | ROIV | ROIVANT SCIENCES LTD | -- | $875,664.95 | 32,017 | BMW4NZ9 |
| 1.10% | ILMN | ILLUMINA INC | -- | $851,020.40 | 6,841 | 2613990 |
| 1.06% | RVMD | REVOLUTION MEDICINES INC | -- | $826,306.65 | 8,865 | BL71K91 |
| 1.06% | INCY | INCYTE CORP | -- | $821,298.52 | 8,902 | 2471950 |
| 0.89% | VTRS | VIATRIS INC | -- | $688,648.59 | 51,507 | BMWS3X9 |
| 0.81% | BBIO | BRIDGEBIO PHARMA INC | -- | $629,486.34 | 8,673 | BK1KWG8 |
| 0.78% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $607,532.40 | 2,754 | BV9G6B8 |
| 0.77% | SMMT | SUMMIT THERAPEUTICS INC | -- | $598,680.36 | 34,686 | BMTVQS7 |
| 0.77% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $594,565.80 | 4,490 | 2623911 |
| 0.76% | MEDP | MEDPACE HOLDINGS INC | -- | $592,115.40 | 1,269 | BDCBC61 |
| 0.71% | IONS | IONIS PHARMACEUTICALS INC | -- | $548,633.60 | 7,390 | BDJ0LS6 |
| 0.69% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $532,766.52 | 1,027 | BD59BS7 |
| 0.67% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $520,919.10 | 2,754 | B4Q5ZN4 |
| 0.67% | GH | GUARDANT HEALTH INC | -- | $516,882.70 | 5,867 | BFXC911 |
| 0.66% | SNY | SANOFI-ADR | -- | $510,442.38 | 10,949 | 2964557 |
| 0.63% | EXEL | EXELIXIS INC | -- | $492,096.12 | 11,617 | 2576941 |
| 0.62% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $477,952.20 | 8,604 | 2437071 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $445,696.16 | 5,096 | BK6H543 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $396,038.50 | 1,430 | BYYWPW6 |
| 0.49% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $380,724.05 | 6,265 | BYQBFJ8 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $376,849.05 | 1,245 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $376,002.59 | 2,289 | BYZR4X4 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $353,813.63 | 7,771 | BSLSJJ0 |
| 0.45% | PCVX | VAXCYTE INC | -- | $352,222.98 | 6,438 | BKPVGH6 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $349,683.78 | 5,509 | BBBSBJ5 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $339,413.58 | 45,991 | BNSP0B8 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $334,171.20 | 5,280 | 2975098 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $329,082.60 | 1,309 | BD6JX35 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $321,048.44 | 3,274 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $300,851.04 | 2,748 | BLC89B2 |
| 0.39% | ACLX | ARCELLX INC | -- | $299,845.92 | 2,616 | BPCJ1Q2 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $292,737.18 | 3,651 | BMPRZV5 |
| 0.38% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $291,695.35 | 2,855 | BDCBCD8 |
| 0.34% | COGT | COGENT BIOSCIENCES INC | -- | $267,713.07 | 7,261 | BLR6XK8 |
| 0.33% | TERN | TERNS PHARMACEUTICALS INC | -- | $252,929.69 | 4,757 | BMDJ0C9 |
| 0.32% | CGON | CG ONCOLOGY INC | -- | $251,879.26 | 3,778 | BRBCSP4 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $250,204.50 | 3,055 | BF2YWG4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $248,101.00 | 3,703 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $239,887.12 | 2,699 | BJDX8Y8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $231,361.26 | 12,622 | BT18HP9 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $230,928.16 | 9,106 | BJRFSB7 |
| 0.29% | ALKS | ALKERMES PLC | -- | $223,053.60 | 7,455 | B3P6D26 |
| 0.27% | ERAS | ERASCA INC | -- | $209,966.00 | 13,850 | BNLYBF3 |
| 0.27% | XENE | XENON PHARMACEUTICALS INC | -- | $206,682.66 | 3,722 | BRJ3GY4 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,132.15 | 4,293 | BDHF4K6 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $201,774.44 | 4,564 | BFZQ0L8 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $192,285.84 | 2,452 | BM9HHL5 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $181,492.25 | 891 | 2501578 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $170,076.04 | 4,684 | BDD19F8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $169,756.56 | 14,076 | BFNF1D6 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $167,540.30 | 5,594 | BTZRLN8 |
| 0.22% | SYRE | SPYRE THERAPEUTICS INC | -- | $166,937.76 | 3,513 | BQBBDY8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $163,730.22 | 7,626 | 2713317 |
| 0.21% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $161,007.00 | 3,485 | BQS9486 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $160,687.50 | 5,142 | BP8JSP4 |
| 0.20% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $157,319.40 | 5,351 | BLB0YQ9 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $151,856.70 | 4,798 | BKY5JZ8 |
| 0.19% | ALMS | ALUMIS INC | -- | $148,839.60 | 5,655 | BPLQG36 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $140,019.83 | 7,095 | BD2B4V0 |
| 0.18% | DYN | DYNE THERAPEUTICS INC | -- | $136,620.75 | 7,365 | BN15WD1 |
| 0.17% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $130,289.18 | 2,565 | B72ZBG4 |
| 0.17% | VERA | VERA THERAPEUTICS INC | -- | $128,509.92 | 3,192 | BL55460 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $128,188.50 | 2,742 | BGKG6G7 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $127,881.60 | 1,903 | BMH5RL1 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $126,081.61 | 3,929 | BK0VHF6 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $124,074.72 | 5,544 | BKX9VD3 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $119,656.50 | 6,025 | BP2P6L0 |
| 0.15% | VCYT | VERACYTE INC | -- | $116,604.00 | 3,555 | BFTWZY0 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $115,225.84 | 4,127 | BLFGJD5 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $108,544.80 | 2,730 | BFXC933 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $107,636.34 | 4,557 | BK6L288 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $107,543.52 | 5,264 | BKS3RS7 |
| 0.14% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $107,263.20 | 11,220 | 2100362 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $105,851.07 | 1,707 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $104,354.24 | 2,656 | BMFD115 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $101,635.84 | 4,688 | B8DPDT7 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $100,865.52 | 5,718 | BYTQ6X1 |
| 0.13% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $98,889.40 | 4,621 | BLB0YH0 |
| 0.13% | ORKA | ORUKA THERAPEUTICS INC | -- | $98,420.90 | 2,165 | BKVF0J2 |
| 0.13% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $97,441.50 | 3,945 | BN7Q7R7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $96,156.48 | 6,888 | BJ5FZ74 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $96,039.34 | 2,053 | BRXB0C0 |
| 0.12% | GRAL | GRAIL INC | -- | $90,914.88 | 1,743 | BSLSSX7 |
| 0.12% | TYRA | TYRA BIOSCIENCES INC | -- | $90,777.61 | 2,387 | BMVNDH9 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $88,321.66 | 10,654 | B9NSBM2 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $86,840.80 | 5,948 | BFWLC09 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $86,460.00 | 4,323 | BJ62Z18 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $86,103.50 | 2,555 | BJQ05Z6 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,472.40 | 4,460 | BV2DHY6 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $83,579.40 | 3,540 | BP9N0G0 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $82,662.12 | 3,348 | BPCQZY9 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $80,909.40 | 7,995 | BN2R582 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $80,587.60 | 1,240 | BDRW1L7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $78,593.73 | 9,739 | BNZB1X8 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,499.74 | 2,866 | BMZ2X38 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $78,498.95 | 2,621 | BCBVTX1 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $75,806.12 | 1,997 | BQKXDX4 |
| 0.10% | INVA | INNOVIVA INC | -- | $75,072.58 | 3,313 | BDDXF67 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $74,940.37 | 2,879 | BBC9WC7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,362.42 | 1,003 | BCDWBX6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $73,549.35 | 23,349 | BM9FJ13 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,438.00 | 4,600 | BMVLGP2 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $71,014.72 | 2,588 | BKSGZN7 |
| 0.09% | VCEL | VERICEL CORP | -- | $69,992.22 | 2,271 | BSBMN89 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,960.16 | 5,284 | BYZM6C2 |
| 0.09% | MAZE | MAZE THERAPEUTICS INC | -- | $68,271.63 | 2,153 | BSRK699 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $67,999.32 | 18,428 | BF0DMK7 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $67,684.80 | 5,736 | BJH9ZN0 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $66,178.11 | 4,913 | BPCK358 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $66,042.24 | 3,776 | BMX9K07 |
| 0.08% | NVAX | NOVAVAX INC | -- | $65,227.60 | 7,288 | BJDQXG4 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $62,997.76 | 7,031 | BK4PZ38 |
| 0.08% | ARDX | ARDELYX INC | -- | $62,419.30 | 10,970 | BN89V40 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $61,828.00 | 2,132 | BR3T9B6 |
| 0.08% | PGEN | PRECIGEN INC | -- | $61,570.92 | 15,828 | BKM5C84 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $59,858.40 | 5,090 | BYSS4X4 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,830.11 | 1,961 | BLCD809 |
| 0.08% | HROW | HARROW INC | -- | $58,660.04 | 1,658 | BHNDW86 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $57,517.92 | 16,248 | BWJDYK1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $56,834.61 | 2,009 | BQXJKH2 |
| 0.07% | ORIC | ORIC PHARMACEUTICALS INC | -- | $55,586.20 | 4,490 | BKVDFF7 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $53,959.60 | 2,435 | BQB42H3 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $53,619.28 | 2,834 | BQB42F1 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $53,450.37 | 3,411 | BP7KZP7 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $52,932.96 | 12,253 | BNC1BX1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $52,210.20 | 8,421 | BYZG9R0 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,974.58 | 3,694 | BYP80F1 |
| 0.07% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $51,521.86 | 923 | BL95N25 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $50,620.20 | 3,585 | BMZ4LN0 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,554.22 | 2,003 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $48,374.24 | 3,704 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,874.24 | 14,776 | BPNTJ34 |
| 0.06% | SVRA | SAVARA INC | -- | $47,790.75 | 9,103 | BYXGN81 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,489.82 | 1,421 | BX7RSN3 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $45,432.70 | 13,562 | BL53SR3 |
| 0.06% | GERN | GERON CORP | -- | $43,976.24 | 28,556 | 2370381 |
| 0.06% | QURE | UNIQURE NV | -- | $43,477.20 | 2,787 | BJFSR88 |
| 0.06% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $42,845.95 | 2,261 | BD06CS0 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $42,829.29 | 651 | BNSP8K3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,191.10 | 1,810 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $41,582.34 | 5,457 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,340.54 | 7,422 | BLR7H87 |
| 0.05% | XNCR | XENCOR INC | -- | $40,389.11 | 3,281 | BGCYWN8 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $40,273.84 | 1,847 | BMGTLY5 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,947.65 | 4,183 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,626.37 | 2,029 | BNFWZS4 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $39,099.75 | 2,775 | BP6C0S2 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,287.80 | 8,604 | BZ0QMB7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $38,023.96 | 3,524 | BJLKVS6 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $37,860.88 | 4,423 | BMCR7V2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $37,464.70 | 2,093 | BZ7PJQ1 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $37,100.86 | 2,722 | BMFX8Y7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,129.81 | 2,643 | BM90J52 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,105.48 | 11,916 | BMFJJ97 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,802.12 | 2,342 | BQS7491 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,435.73 | 2,267 | BMNDK09 |
| 0.04% | PSNL | PERSONALIS INC | -- | $34,264.92 | 4,681 | BJQ0608 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,993.75 | 6,475 | BMVV9R5 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $33,499.18 | 7,579 | BYWVTY5 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $32,851.00 | 1,330 | BKLCWZ3 |
| 0.04% | OMER | OMEROS CORP | -- | $32,661.30 | 3,171 | B4NB858 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,537.12 | 3,892 | BYZD465 |
| 0.04% | MNKD | MANNKIND CORP | -- | $31,700.90 | 13,783 | BF081J4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,590.00 | 1,944 | BT9K6D8 |
| 0.04% | ARVN | ARVINAS INC | -- | $31,109.94 | 2,862 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,477.90 | 10,694 | BBNBTD2 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,393.00 | 8,075 | BPBJFM7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $28,116.55 | 1,199 | BGL0JK3 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $27,852.76 | 3,694 | BDDVW37 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,289.08 | 2,548 | BMFK3H6 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,108.00 | 3,600 | BFYQFJ2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,946.78 | 3,486 | BQHN6C7 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $26,842.83 | 1,533 | BD9GVY0 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,838.40 | 840 | BPBPCG8 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $25,213.06 | 1,858 | BRJJYT3 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $24,227.73 | 10,053 | BFZNYB7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $23,800.80 | 4,220 | BMC3HS7 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,672.22 | 2,418 | BRCFFK6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,659.80 | 2,517 | BLFBZ32 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,610.80 | 3,524 | BJ0LT31 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $23,556.45 | 4,857 | BMXNGZ6 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $23,230.76 | 2,282 | BKLXFX5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,938.30 | 7,282 | B3MZ6K5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,924.16 | 2,408 | B91XRN2 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $22,784.02 | 4,858 | BDFKQ07 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,596.12 | 5,458 | BYVQJ96 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,438.81 | 813 | BQD3J33 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,215.82 | 2,581 | B2Q9833 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,087.03 | 1,713 | BP81RK8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $20,674.26 | 2,979 | BJDX8Z9 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,524.68 | 2,556 | BSMLR16 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,236.41 | 6,549 | BMCWKZ2 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,900.08 | 664 | B292NQ7 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,370.88 | 6,726 | BN94K69 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,229.22 | 951 | BTNMG41 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $18,990.40 | 5,395 | BYV2W40 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,896.48 | 2,654 | B12W3P6 |
| 0.02% | IVVD | INVIVYD INC | -- | $18,717.96 | 12,396 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,700.64 | 2,264 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $18,628.35 | 3,495 | BLN9Z50 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $18,612.75 | 7,475 | BN4JN37 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,591.30 | 1,362 | BPRBTY7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,447.25 | 3,265 | BQ6C357 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,296.04 | 2,841 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,237.15 | 13,509 | B4N8MH9 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,926.40 | 5,602 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,250.49 | 1,299 | B9L5200 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,957.60 | 3,270 | BP0TQC5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $15,891.84 | 3,204 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,102.04 | 1,363 | BM7V485 |
| 0.02% | PEPG | PEPGEN INC | -- | $15,041.64 | 3,076 | BMTX3D7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,981.40 | 2,870 | BMVBZF5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,815.72 | 692 | BS2F741 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,270.52 | 2,276 | B7F2TY6 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,007.89 | 4,501 | BZC0D70 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,838.00 | 2,620 | BMF7DT9 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,803.55 | 5,021 | BKRRKY7 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,507.06 | 1,399 | BQV0J03 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,142.92 | 4,306 | BK5MWR1 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,088.83 | 2,899 | BDRJH21 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,940.48 | 4,146 | BYTYP72 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,575.17 | 8,973 | BFMLGR4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,433.68 | 4,364 | BKX9NQ0 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,337.25 | 2,525 | BPRB2N7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,151.00 | 2,100 | BL5B6Z1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,100.42 | 6,687 | BRK0149 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,890.81 | 2,637 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $10,173.62 | 6,439 | BN13S71 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,129.12 | 4,366 | BZ8FPH3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,328.50 | 2,073 | BKDQKM6 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,998.68 | 1,271 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,985.71 | 4,181 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,082.46 | 1,386 | BP2NYN2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,069.66 | 8,742 | BNR5QT9 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,795.93 | 9,696 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,775.02 | 2,394 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,719.93 | 8,633 | BMYTJP4 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,708.06 | 4,041 | B5LL2C2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,706.40 | 3,320 | BPTK6Z2 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,482.25 | 1,675 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,429.37 | 2,549 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,712.04 | 4,363 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,880.68 | 10,354 | BJ0CK86 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,872.54 | 2,786 | BLBR8D5 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,415.23 | 973 | BTXQTX3 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $24.91 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 32.40% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,153,216 | -- | 4,400 | -- |
| 31.54% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,484,369 | -- | 4,283 | -- |
| 27.26% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,163,001 | -- | 3,702 | -- |
| 19.43% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,086,213 | -- | 2,639 | -- |
| 14.65% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,376,114 | -- | 1,990 | -- |
| 4.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,618,633 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $23,156,575.30 | 23,156,575 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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