BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,655,301
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/29/2026- NAV
- NAV Change
- Market Price $84.59
- Market Price Change $-0.25
- Trading Volume (M) 2,709
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,655,301
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/29/2026- NAV
- NAV Change
- Market Price $84.59
- Market Price Change $-0.25
- Trading Volume (M) 2,709
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/29/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.66% | GILD | GILEAD SCIENCES INC | -- | $3,433,611.06 | 25,542 | 2369174 |
| 4.65% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,426,813.78 | 7,657 | 2931034 |
| 4.48% | AMGN | AMGEN INC | -- | $3,301,552.37 | 9,803 | 2023607 |
| 3.21% | REGN | REGENERON PHARMACEUTICALS | -- | $2,360,755.20 | 3,840 | 2730190 |
| 2.01% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,480,909.92 | 4,904 | B00FWN1 |
| 1.57% | RVMD | REVOLUTION MEDICINES INC | -- | $1,153,698.48 | 7,326 | BL71K91 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,063,300.00 | 5,425 | 2455965 |
| 1.25% | ILMN | ILLUMINA INC | -- | $921,212.88 | 5,653 | 2613990 |
| 1.22% | UTHR | UNITED THERAPEUTICS CORP | -- | $902,048.40 | 1,620 | 2430412 |
| 1.20% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $883,071.12 | 15,837 | BMVP7Y0 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $877,789.50 | 1,050 | BDVLM39 |
| 1.16% | INSM | INSMED INC | -- | $851,858.88 | 7,968 | 2614487 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $793,535.40 | 26,460 | BMW4NZ9 |
| 0.97% | INCY | INCYTE CORP | -- | $711,909.66 | 7,359 | 2471950 |
| 0.94% | VTRS | VIATRIS INC | -- | $692,106.90 | 42,565 | BMWS3X9 |
| 0.94% | MRNA | MODERNA INC | -- | $688,974.00 | 14,600 | BGSXTS3 |
| 0.85% | GH | GUARDANT HEALTH INC | -- | $628,996.50 | 4,850 | BFXC911 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $587,609.60 | 3,712 | 2623911 |
| 0.73% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $538,014.75 | 2,275 | B4Q5ZN4 |
| 0.69% | ASND | ASCENDIS PHARMA A/S | -- | $510,074.36 | 2,276 | BWXJHM8 |
| 0.68% | SMMT | SUMMIT THERAPEUTICS INC | -- | $502,766.56 | 28,664 | BMTVQS7 |
| 0.66% | EXEL | EXELIXIS INC | -- | $484,608.00 | 9,600 | 2576941 |
| 0.64% | BBIO | BRIDGEBIO PHARMA INC | -- | $474,885.42 | 7,167 | BK1KWG8 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $469,912.61 | 1,051 | BDCBC61 |
| 0.63% | IONS | IONIS PHARMACEUTICALS INC | -- | $467,338.50 | 6,109 | BDJ0LS6 |
| 0.60% | AXSM | AXSOME THERAPEUTICS INC | -- | $443,167.20 | 1,890 | BYZR4X4 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $421,187.69 | 847 | BD59BS7 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $407,331.90 | 7,110 | 2437071 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $404,237.35 | 4,213 | BK6H543 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $403,417.98 | 5,178 | BYQBFJ8 |
| 0.54% | SNY | SANOFI-ADR | -- | $395,082.49 | 9,047 | 2964557 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $360,119.13 | 1,029 | BQ721R4 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $349,488.28 | 4,553 | BBBSBJ5 |
| 0.46% | ONC | BEONE MEDICINES LTD-ADR | -- | $340,033.52 | 1,181 | BYYWPW6 |
| 0.45% | KRYS | KRYSTAL BIOTECH INC | -- | $333,752.40 | 1,080 | BD6JX35 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $324,219.28 | 6,424 | BSLSJJ0 |
| 0.41% | ABVX | ABIVAX SA-ADR | -- | $301,202.73 | 2,271 | BLC89B2 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $298,604.95 | 2,705 | BMVBZD3 |
| 0.39% | HALO | HALOZYME THERAPEUTICS INC | -- | $290,380.56 | 4,364 | 2975098 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $285,820.16 | 38,008 | BNSP0B8 |
| 0.37% | PCVX | VAXCYTE INC | -- | $273,499.40 | 5,321 | BKPVGH6 |
| 0.35% | ALKS | ALKERMES PLC | -- | $260,016.97 | 6,163 | B3P6D26 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $250,515.90 | 7,523 | BJRFSB7 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $245,644.14 | 3,017 | BMPRZV5 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $235,061.16 | 2,361 | BDCBCD8 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $226,446.50 | 2,231 | BJDX8Y8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $226,128.70 | 3,062 | B17VCN9 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $223,096.32 | 2,526 | BF2YWG4 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $213,517.50 | 2,905 | BQBBDY8 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $209,829.92 | 6,002 | BLR6XK8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $199,439.00 | 3,550 | BDHF4K6 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $194,531.67 | 3,123 | BRBCSP4 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $186,008.90 | 3,773 | BFZQ0L8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,858.48 | 4,423 | BLB0YQ9 |
| 0.24% | CAI | CARIS LIFE SCIENCES INC | -- | $174,406.32 | 10,431 | BT18HP9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $170,722.56 | 736 | 2501578 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $168,240.02 | 3,074 | BRJ3GY4 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $166,579.92 | 2,028 | BM9HHL5 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $166,556.48 | 4,624 | BTZRLN8 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $160,836.62 | 3,409 | BLFGJD5 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $153,193.44 | 11,632 | BFNF1D6 |
| 0.21% | TWST | TWIST BIOSCIENCE CORP | -- | $151,527.42 | 2,266 | BGKG6G7 |
| 0.20% | ERAS | ERASCA INC | -- | $146,940.96 | 11,444 | BNLYBF3 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $143,207.36 | 4,252 | BP8JSP4 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $137,649.60 | 3,872 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $136,522.98 | 6,303 | 2713317 |
| 0.18% | VCYT | VERACYTE INC | -- | $136,146.92 | 2,938 | BFTWZY0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $135,478.56 | 3,966 | BKY5JZ8 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $124,047.31 | 3,767 | BK6L288 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $123,357.52 | 5,863 | BD2B4V0 |
| 0.17% | TXG | 10X GENOMICS INC-CLASS A | -- | $123,155.06 | 4,351 | BKS3RS7 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $117,661.71 | 6,087 | BN15WD1 |
| 0.15% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $113,299.20 | 2,880 | BQS9486 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $109,416.44 | 4,978 | BP2P6L0 |
| 0.14% | ORKA | ORUKA THERAPEUTICS INC | -- | $104,710.17 | 1,789 | BKVF0J2 |
| 0.14% | GRAL | GRAIL INC | -- | $103,147.52 | 1,439 | BSLSSX7 |
| 0.14% | ALMS | ALUMIS INC | -- | $100,958.40 | 4,674 | BPLQG36 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $98,437.02 | 4,587 | BKX9VD3 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $98,163.27 | 1,411 | BMGJZJ8 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $97,901.60 | 2,120 | B72ZBG4 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $95,659.62 | 3,246 | BK0VHF6 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $93,630.72 | 2,636 | BL55460 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $93,436.20 | 1,573 | BMH5RL1 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $92,814.30 | 6,606 | BN2R582 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $92,137.50 | 2,925 | BP9N0G0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $89,140.15 | 3,685 | BV2DHY6 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $86,895.72 | 2,196 | BMFD115 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $86,233.80 | 5,692 | BJ5FZ74 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $85,489.74 | 3,571 | BJ62Z18 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $84,793.52 | 3,122 | BMX9K07 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $82,781.05 | 2,255 | BFXC933 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $82,604.61 | 9,271 | 2100362 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $82,149.24 | 1,698 | BRXB0C0 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $75,331.62 | 4,914 | BFWLC09 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $72,521.49 | 8,049 | BNZB1X8 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $71,721.36 | 4,209 | BYSS4X4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $71,388.72 | 2,367 | BMZ2X38 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $70,695.82 | 1,651 | BQKXDX4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $70,263.90 | 8,805 | B9NSBM2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $69,678.00 | 1,764 | BR3T9B6 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $69,509.58 | 2,766 | BPCQZY9 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $69,276.23 | 19,297 | BM9FJ13 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $69,246.25 | 3,875 | B8DPDT7 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $69,159.53 | 11,209 | BL53SR3 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $67,602.60 | 2,140 | BKSGZN7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $67,523.52 | 3,802 | BMVLGP2 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $67,051.88 | 4,742 | BJH9ZN0 |
| 0.09% | NVAX | NOVAVAX INC | -- | $66,072.31 | 6,023 | BJDQXG4 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $65,951.34 | 1,974 | BMVNDH9 |
| 0.09% | QURE | UNIQURE NV | -- | $65,761.65 | 2,305 | BJFSR88 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $65,251.01 | 2,111 | BJQ05Z6 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $65,163.30 | 830 | BCDWBX6 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $63,882.99 | 3,261 | BN7Q7R7 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $63,680.40 | 2,166 | BCBVTX1 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $62,639.07 | 2,379 | BBC9WC7 |
| 0.08% | VCEL | VERICEL CORP | -- | $62,493.75 | 1,875 | BSBMN89 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $62,451.20 | 15,232 | BF0DMK7 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $61,471.83 | 4,369 | BYZM6C2 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $60,833.37 | 13,429 | BWJDYK1 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,451.36 | 10,128 | BNC1BX1 |
| 0.08% | INVA | INNOVIVA INC | -- | $58,690.80 | 2,740 | BDDXF67 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $58,246.65 | 4,059 | BPCK358 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $56,950.41 | 1,023 | BDRW1L7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $56,767.20 | 13,080 | BKM5C84 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,853.37 | 537 | BNSP8K3 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $55,542.78 | 2,818 | BP7KZP7 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $55,427.40 | 5,810 | BK4PZ38 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $55,033.06 | 2,294 | BP6C0S2 |
| 0.07% | ARDX | ARDELYX INC | -- | $54,758.64 | 9,066 | BN89V40 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $53,172.45 | 3,455 | BRXYZ57 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,177.26 | 1,658 | BQXJKH2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $50,960.25 | 2,343 | BQB42F1 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,246.90 | 1,870 | BD06CS0 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,041.40 | 1,657 | BQNKXX2 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $48,664.90 | 1,730 | BZ7PJQ1 |
| 0.07% | HROW | HARROW INC | -- | $48,237.70 | 1,370 | BHNDW86 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $47,045.88 | 1,778 | BSRK699 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,830.69 | 1,621 | BLCD809 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,222.29 | 1,527 | BMGTLY5 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $45,796.80 | 6,960 | BYZG9R0 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $45,540.22 | 3,487 | BMC3HS7 |
| 0.06% | PSNL | PERSONALIS INC | -- | $44,106.60 | 3,869 | BJQ0608 |
| 0.06% | MNKD | MANNKIND CORP | -- | $42,936.53 | 11,389 | BF081J4 |
| 0.06% | EYPT | EYEPOINT INC | -- | $41,581.96 | 3,062 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $41,025.60 | 12,210 | BPNTJ34 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,390.92 | 1,172 | BX7RSN3 |
| 0.05% | SVRA | SAVARA INC | -- | $39,124.80 | 7,524 | BYXGN81 |
| 0.05% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $39,068.78 | 2,962 | BMZ4LN0 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $37,900.14 | 3,054 | BYP80F1 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $37,785.44 | 6,134 | BLR7H87 |
| 0.05% | ABSI | ABSCI CORP | -- | $37,536.75 | 5,561 | BN94K69 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,487.20 | 1,983 | BQB42H3 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,921.40 | 2,185 | BM90J52 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $35,403.50 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,713.90 | 1,495 | B3X26D8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,159.92 | 3,656 | BMCR7V2 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $32,842.09 | 2,251 | BMFX8Y7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,823.60 | 3,218 | BYZD465 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $32,501.70 | 9,849 | BMFJJ97 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,421.60 | 7,110 | BZ0QMB7 |
| 0.04% | XNCR | XENCOR INC | -- | $32,206.68 | 2,711 | BGCYWN8 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,683.75 | 2,975 | BFYQFJ2 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $31,611.45 | 1,677 | BNFWZS4 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,357.95 | 3,711 | BKVDFF7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,206.40 | 992 | BGL0JK3 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,112.50 | 1,875 | BMNDK09 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $29,783.60 | 1,934 | BQS7491 |
| 0.04% | GERN | GERON CORP | -- | $29,502.50 | 23,602 | 2370381 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,991.58 | 5,349 | BMVV9R5 |
| 0.04% | OMER | OMEROS CORP | -- | $28,946.88 | 2,622 | B4NB858 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $27,926.08 | 2,912 | BJLKVS6 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $27,733.16 | 1,604 | BT9K6D8 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $26,530.57 | 3,053 | BDDVW37 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $25,968.00 | 5,410 | BMCWKZ2 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,568.84 | 2,911 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,141.97 | 2,083 | BLFBZ32 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $23,689.15 | 6,673 | BPBJFM7 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,492.77 | 763 | BL95N25 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,188.00 | 1,100 | BKLCWZ3 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $22,993.92 | 1,536 | BRJJYT3 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $22,554.00 | 6,265 | BYWVTY5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,468.10 | 2,707 | BP0TQC5 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $22,448.61 | 1,269 | BD9GVY0 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,060.40 | 2,105 | BMFK3H6 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,597.35 | 693 | BPBPCG8 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $21,519.96 | 6,028 | B3MZ6K5 |
| 0.03% | ARVN | ARVINAS INC | -- | $21,219.74 | 2,363 | BDZ30Q0 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $21,139.20 | 2,880 | BQHN6C7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,489.28 | 672 | BQD3J33 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,288.45 | 4,459 | BYV2W40 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,248.02 | 1,989 | B91XRN2 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,680.35 | 1,885 | BKLXFX5 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,134.22 | 4,511 | BYVQJ96 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $18,028.36 | 8,308 | BFZNYB7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,994.24 | 2,112 | BSMLR16 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,547.03 | 2,349 | BP81R42 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $17,050.88 | 2,464 | BJDX8Z9 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,694.92 | 1,997 | BRCFFK6 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,666.54 | 2,134 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $16,632.87 | 11,163 | B4N8MH9 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,327.08 | 1,023 | BS2CR64 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,182.14 | 571 | BS2F741 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,771.33 | 3,609 | BKX9NQ0 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,724.32 | 2,397 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,535.80 | 548 | B292NQ7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,162.76 | 1,124 | BPRBTY7 |
| 0.02% | OABI | OMNIAB INC | -- | $14,369.40 | 5,322 | BN13S71 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,124.55 | 4,631 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,107.52 | 1,072 | B9L5200 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,099.70 | 2,186 | B12W3P6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,968.72 | 4,014 | BMXNGZ6 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,864.18 | 7,414 | BFMLGR4 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,862.58 | 2,697 | BQ6C357 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,772.99 | 2,387 | BMVBZF5 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,638.71 | 787 | BTNMG41 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $13,491.63 | 2,889 | BLN9Z50 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,472.43 | 1,879 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,445.46 | 3,557 | BK5MWR1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $13,129.73 | 1,873 | BZ0G875 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,656.25 | 1,125 | BM7V485 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,494.06 | 3,611 | BZ8FPH3 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,383.28 | 2,646 | 2107437 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,319.91 | 4,013 | BDFKQ07 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,978.40 | 1,736 | BL5B6Z1 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,678.16 | 10,244 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,425.60 | 6,176 | BN4JN37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $10,697.40 | 1,981 | BP7L561 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $10,380.78 | 3,426 | BYTYP72 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,011.12 | 1,416 | BP81RK8 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,897.86 | 3,721 | BZC0D70 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,276.80 | 7,136 | BMYTJP4 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,266.20 | 2,165 | BMF7DT9 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,254.57 | 3,341 | B5LL2C2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $9,009.24 | 1,158 | BQV0J03 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,784.75 | 5,525 | BRK0149 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,603.70 | 7,230 | BNR5QT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,432.73 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,361.63 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,331.84 | 1,052 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,167.99 | 2,089 | BPRB2N7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,151.44 | 3,454 | BNYJR68 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,024.59 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,637.84 | 4,151 | BKRRKY7 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,962.74 | 1,387 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,962.43 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,034.60 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,673.10 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,145.40 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,811.50 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,430.49 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,304.44 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,975.35 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 33.11% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 24,384,517 | -- | 4,071 | -- |
| 28.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,108,090 | -- | 3,524 | -- |
| 27.44% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,209,619 | -- | 3,374 | -- |
| 21.46% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,807,109 | -- | 2,639 | -- |
| 20.44% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 15,052,393 | -- | 2,513 | -- |
| 5.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,791,550 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $22,215,864.92 | 22,215,865 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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