BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,951,994
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/17/2026- NAV
- NAV Change
- Market Price $84.95
- Market Price Change $+1.84
- Trading Volume (M) 21,891
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,951,994
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/17/2026- NAV
- NAV Change
- Market Price $84.95
- Market Price Change $+1.84
- Trading Volume (M) 21,891
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/17/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.75% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,514,486.43 | 7,657 | 2931034 |
| 4.53% | AMGN | AMGEN INC | -- | $3,349,292.98 | 9,803 | 2023607 |
| 4.33% | GILD | GILEAD SCIENCES INC | -- | $3,204,243.90 | 25,542 | 2369174 |
| 3.16% | REGN | REGENERON PHARMACEUTICALS | -- | $2,334,451.20 | 3,840 | 2730190 |
| 1.87% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,386,458.88 | 4,904 | B00FWN1 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,155,823.02 | 7,326 | BL71K91 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,077,784.75 | 5,425 | 2455965 |
| 1.27% | ARGX | ARGENX SE - ADR | -- | $936,873.00 | 1,050 | BDVLM39 |
| 1.22% | MRNA | MODERNA INC | -- | $902,280.00 | 14,600 | BGSXTS3 |
| 1.22% | ILMN | ILLUMINA INC | -- | $899,335.77 | 5,653 | 2613990 |
| 1.21% | UTHR | UNITED THERAPEUTICS CORP | -- | $893,381.40 | 1,620 | 2430412 |
| 1.15% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $850,446.90 | 15,837 | BMVP7Y0 |
| 1.12% | ROIV | ROIVANT SCIENCES LTD | -- | $825,552.00 | 26,460 | BMW4NZ9 |
| 1.06% | INSM | INSMED INC | -- | $784,449.60 | 7,968 | 2614487 |
| 0.99% | INCY | INCYTE CORP | -- | $728,467.41 | 7,359 | 2471950 |
| 0.91% | VTRS | VIATRIS INC | -- | $669,547.45 | 42,565 | BMWS3X9 |
| 0.85% | GH | GUARDANT HEALTH INC | -- | $626,183.50 | 4,850 | BFXC911 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $590,208.00 | 3,712 | 2623911 |
| 0.71% | ASND | ASCENDIS PHARMA A/S | -- | $526,097.40 | 2,276 | BWXJHM8 |
| 0.70% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $516,265.75 | 2,275 | B4Q5ZN4 |
| 0.68% | EXEL | EXELIXIS INC | -- | $503,424.00 | 9,600 | 2576941 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $482,984.13 | 7,167 | BK1KWG8 |
| 0.65% | MEDP | MEDPACE HOLDINGS INC | -- | $480,401.59 | 1,051 | BDCBC61 |
| 0.64% | AXSM | AXSOME THERAPEUTICS INC | -- | $476,582.40 | 1,890 | BYZR4X4 |
| 0.61% | IONS | IONIS PHARMACEUTICALS INC | -- | $453,959.79 | 6,109 | BDJ0LS6 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $423,381.42 | 847 | BD59BS7 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $419,625.12 | 5,178 | BYQBFJ8 |
| 0.55% | SMMT | SUMMIT THERAPEUTICS INC | -- | $403,302.48 | 28,664 | BMTVQS7 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $391,192.20 | 7,110 | 2437071 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $388,522.86 | 4,213 | BK6H543 |
| 0.52% | SNY | SANOFI-ADR | -- | $384,497.50 | 9,047 | 2964557 |
| 0.50% | KRYS | KRYSTAL BIOTECH INC | -- | $368,992.80 | 1,080 | BD6JX35 |
| 0.48% | CYTK | CYTOKINETICS INC | -- | $355,634.83 | 4,553 | BBBSBJ5 |
| 0.45% | NUVL | NUVALENT INC-A | -- | $333,688.80 | 2,705 | BMVBZD3 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $313,426.96 | 6,424 | BSLSJJ0 |
| 0.42% | ONC | BEONE MEDICINES LTD-ADR | -- | $310,225.08 | 1,181 | BYYWPW6 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $299,239.48 | 4,364 | 2975098 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $277,840.29 | 1,029 | BQ721R4 |
| 0.37% | ALKS | ALKERMES PLC | -- | $274,315.13 | 6,163 | B3P6D26 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $271,228.30 | 3,017 | BMPRZV5 |
| 0.36% | PCVX | VAXCYTE INC | -- | $269,615.07 | 5,321 | BKPVGH6 |
| 0.36% | IBRX | IMMUNITYBIO INC | -- | $265,675.92 | 38,008 | BNSP0B8 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $263,109.84 | 2,361 | BDCBCD8 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $261,123.33 | 7,523 | BJRFSB7 |
| 0.34% | SYRE | SPYRE THERAPEUTICS INC | -- | $254,158.45 | 2,905 | BQBBDY8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $242,066.58 | 2,526 | BF2YWG4 |
| 0.33% | PTCT | PTC THERAPEUTICS INC | -- | $240,458.86 | 3,062 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $227,651.24 | 2,231 | BJDX8Y8 |
| 0.31% | ABVX | ABIVAX SA-ADR | -- | $227,440.65 | 2,271 | BLC89B2 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $202,087.34 | 6,002 | BLR6XK8 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $193,671.04 | 736 | 2501578 |
| 0.26% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $189,368.96 | 11,632 | BFNF1D6 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $188,722.89 | 3,123 | BRBCSP4 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $188,469.50 | 3,550 | BDHF4K6 |
| 0.25% | TWST | TWIST BIOSCIENCE CORP | -- | $187,783.42 | 2,266 | BGKG6G7 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $186,297.66 | 10,431 | BT18HP9 |
| 0.25% | TVTX | TRAVERE THERAPEUTICS INC | -- | $184,563.26 | 3,409 | BLFGJD5 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $179,336.04 | 2,028 | BM9HHL5 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $177,142.35 | 3,773 | BFZQ0L8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,345.01 | 4,423 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $175,388.32 | 4,624 | BTZRLN8 |
| 0.22% | XENE | XENON PHARMACEUTICALS INC | -- | $163,536.80 | 3,074 | BRJ3GY4 |
| 0.22% | TNGX | TANGO THERAPEUTICS INC | -- | $160,739.62 | 4,978 | BP2P6L0 |
| 0.22% | ERAS | ERASCA INC | -- | $159,987.12 | 11,444 | BNLYBF3 |
| 0.20% | VCYT | VERACYTE INC | -- | $150,690.02 | 2,938 | BFTWZY0 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $139,797.63 | 4,351 | BKS3RS7 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $138,424.00 | 3,872 | BDD19F8 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $138,096.12 | 3,966 | BKY5JZ8 |
| 0.19% | DNLI | DENALI THERAPEUTICS INC | -- | $137,721.87 | 5,863 | BD2B4V0 |
| 0.18% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $136,144.80 | 6,303 | 2713317 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $129,600.00 | 2,880 | BQS9486 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $128,197.80 | 4,252 | BP8JSP4 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $126,804.32 | 1,789 | BKVF0J2 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $122,352.16 | 3,767 | BK6L288 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $120,271.14 | 4,587 | BKX9VD3 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $116,870.40 | 6,087 | BN15WD1 |
| 0.15% | QURE | UNIQURE NV | -- | $111,008.80 | 2,305 | BJFSR88 |
| 0.15% | ALMS | ALUMIS INC | -- | $107,735.70 | 4,674 | BPLQG36 |
| 0.14% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $104,649.44 | 3,122 | BMX9K07 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $102,789.36 | 6,606 | BN2R582 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $101,469.96 | 3,246 | BK0VHF6 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $99,066.31 | 1,411 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $98,512.56 | 2,196 | BMFD115 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $98,391.15 | 1,573 | BMH5RL1 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $96,095.61 | 3,571 | BJ62Z18 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $95,511.76 | 5,692 | BJ5FZ74 |
| 0.12% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $92,389.60 | 2,120 | B72ZBG4 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $92,286.36 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $92,048.58 | 1,698 | BRXB0C0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $90,024.55 | 3,685 | BV2DHY6 |
| 0.12% | GRAL | GRAIL INC | -- | $85,548.55 | 1,439 | BSLSSX7 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $82,975.45 | 9,271 | 2100362 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $80,526.05 | 2,255 | BFXC933 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $79,311.96 | 4,914 | BFWLC09 |
| 0.11% | PHVS | PHARVARIS NV | -- | $79,081.47 | 2,367 | BMZ2X38 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $77,626.54 | 4,742 | BJH9ZN0 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $77,592.36 | 8,049 | BNZB1X8 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $75,130.65 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $74,138.10 | 8,805 | B9NSBM2 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $73,505.25 | 2,925 | BP9N0G0 |
| 0.10% | VCEL | VERICEL CORP | -- | $73,368.75 | 1,875 | BSBMN89 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,267.80 | 2,140 | BKSGZN7 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $71,651.28 | 2,166 | BCBVTX1 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $68,956.22 | 1,658 | BQXJKH2 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $66,831.60 | 830 | BCDWBX6 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $66,408.80 | 4,369 | BYZM6C2 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,720.00 | 3,875 | B8DPDT7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $65,090.24 | 3,802 | BMVLGP2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,038.68 | 1,764 | BR3T9B6 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $64,005.24 | 2,766 | BPCQZY9 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $63,878.86 | 2,111 | BJQ05Z6 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $62,692.32 | 10,128 | BNC1BX1 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $62,089.44 | 3,261 | BN7Q7R7 |
| 0.08% | INVA | INNOVIVA INC | -- | $62,033.60 | 2,740 | BDDXF67 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $61,899.75 | 4,059 | BPCK358 |
| 0.08% | PGEN | PRECIGEN INC | -- | $61,868.40 | 13,080 | BKM5C84 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $60,976.96 | 11,209 | BL53SR3 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $60,641.23 | 1,651 | BQKXDX4 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $60,402.81 | 2,379 | BBC9WC7 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,013.67 | 19,297 | BM9FJ13 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $59,861.76 | 15,232 | BF0DMK7 |
| 0.08% | SEPN | SEPTERNA INC | -- | $59,320.60 | 1,657 | BQNKXX2 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $58,075.71 | 1,023 | BDRW1L7 |
| 0.08% | HROW | HARROW INC | -- | $57,457.80 | 1,370 | BHNDW86 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $57,384.18 | 1,974 | BMVNDH9 |
| 0.08% | NVAX | NOVAVAX INC | -- | $57,218.50 | 6,023 | BJDQXG4 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $56,761.30 | 1,730 | BZ7PJQ1 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $54,656.03 | 13,429 | BWJDYK1 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,033.00 | 5,810 | BK4PZ38 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $53,701.56 | 2,343 | BQB42F1 |
| 0.07% | ARDX | ARDELYX INC | -- | $52,945.44 | 9,066 | BN89V40 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $52,930.60 | 3,455 | BRXYZ57 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $51,879.38 | 2,818 | BP7KZP7 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,585.40 | 537 | BNSP8K3 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $49,779.80 | 2,294 | BP6C0S2 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $47,886.72 | 1,527 | BMGTLY5 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,802.15 | 12,210 | BPNTJ34 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,279.55 | 1,621 | BLCD809 |
| 0.06% | MNKD | MANNKIND CORP | -- | $44,644.88 | 11,389 | BF081J4 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $44,165.52 | 1,778 | BSRK699 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,324.60 | 6,134 | BLR7H87 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $41,634.78 | 3,487 | BMC3HS7 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $41,412.00 | 6,960 | BYZG9R0 |
| 0.05% | SVRA | SAVARA INC | -- | $40,479.12 | 7,524 | BYXGN81 |
| 0.05% | EYPT | EYEPOINT INC | -- | $40,265.30 | 3,062 | BMGS7L1 |
| 0.05% | ABSI | ABSCI CORP | -- | $39,927.98 | 5,561 | BN94K69 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,472.96 | 1,172 | BX7RSN3 |
| 0.05% | PSNL | PERSONALIS INC | -- | $37,722.75 | 3,869 | BJQ0608 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,844.14 | 1,983 | BQB42H3 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $36,648.00 | 3,054 | BYP80F1 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,194.40 | 3,656 | BMCR7V2 |
| 0.05% | XNCR | XENCOR INC | -- | $34,646.58 | 2,711 | BGCYWN8 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,846.80 | 1,495 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,644.60 | 4,510 | B8K7T65 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $32,550.57 | 1,677 | BNFWZS4 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,497.92 | 992 | BGL0JK3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,063.96 | 1,604 | BT9K6D8 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $32,032.00 | 2,912 | BJLKVS6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $32,025.93 | 3,711 | BKVDFF7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $31,851.65 | 2,251 | BMFX8Y7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,551.40 | 2,185 | BM90J52 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,497.30 | 7,110 | BZ0QMB7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,331.25 | 1,875 | BMNDK09 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,969.75 | 2,975 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $30,796.26 | 3,218 | BYZD465 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $30,530.00 | 3,053 | BDDVW37 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $29,940.96 | 9,849 | BMFJJ97 |
| 0.04% | GERN | GERON CORP | -- | $29,030.46 | 23,602 | 2370381 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $28,240.20 | 5,410 | BMCWKZ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $28,013.29 | 8,837 | BBNBTD2 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $27,961.28 | 2,962 | BMZ4LN0 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $27,017.98 | 1,934 | BQS7491 |
| 0.04% | ANNX | ANNEXON INC | -- | $26,424.06 | 5,349 | BMVV9R5 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,266.63 | 2,083 | BLFBZ32 |
| 0.03% | OMER | OMEROS CORP | -- | $25,276.08 | 2,622 | B4NB858 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,238.37 | 2,911 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,112.65 | 2,105 | BMFK3H6 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,530.92 | 763 | BL95N25 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,070.72 | 1,536 | BRJJYT3 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $22,689.72 | 1,269 | BD9GVY0 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,424.64 | 672 | BQD3J33 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,275.00 | 1,100 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,628.93 | 2,707 | BP0TQC5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $21,218.56 | 6,028 | B3MZ6K5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $21,086.68 | 6,673 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $21,052.80 | 2,880 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,831.58 | 693 | BPBPCG8 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,983.73 | 4,511 | BYVQJ96 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,708.78 | 4,459 | BYV2W40 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $18,587.91 | 1,023 | BS2CR64 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,544.40 | 6,265 | BYWVTY5 |
| 0.02% | ARVN | ARVINAS INC | -- | $18,124.21 | 2,363 | BDZ30Q0 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $17,756.70 | 1,885 | BKLXFX5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,581.09 | 571 | BS2F741 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,980.48 | 2,112 | BSMLR16 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,886.61 | 1,989 | B91XRN2 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,283.68 | 8,308 | BFZNYB7 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,155.78 | 2,397 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,546.76 | 548 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,492.84 | 2,134 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,958.42 | 11,163 | B4N8MH9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,822.19 | 2,349 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $14,796.70 | 1,873 | BZ0G875 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,209.56 | 4,014 | BMXNGZ6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $14,147.28 | 3,609 | BKX9NQ0 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,667.84 | 1,124 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,585.17 | 1,879 | B7F2TY6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,550.08 | 1,072 | B9L5200 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,431.06 | 2,697 | BQ6C357 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,028.56 | 2,186 | B12W3P6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,681.08 | 4,013 | BDFKQ07 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,509.37 | 2,889 | BLN9Z50 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,281.55 | 1,997 | BRCFFK6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,225.84 | 4,631 | BFY7DC4 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,735.36 | 1,736 | BL5B6Z1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,711.25 | 1,125 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,404.26 | 2,646 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,343.42 | 7,414 | BFMLGR4 |
| 0.01% | OABI | OMNIAB INC | -- | $10,803.66 | 5,322 | BN13S71 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,526.67 | 2,387 | BMVBZF5 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $10,101.88 | 3,557 | BK5MWR1 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,853.24 | 787 | BTNMG41 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,805.95 | 1,981 | BP7L561 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,642.96 | 1,416 | BP81RK8 |
| 0.01% | IVVD | INVIVYD INC | -- | $9,539.21 | 10,244 | BM8NHS1 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,449.28 | 6,176 | BN4JN37 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,208.05 | 3,611 | BZ8FPH3 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,147.42 | 3,426 | BYTYP72 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,768.25 | 2,165 | BMF7DT9 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,707.14 | 3,721 | BZC0D70 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,624.00 | 2,464 | BJDX8Z9 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,285.68 | 3,341 | B5LL2C2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,084.43 | 2,089 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,887.98 | 2,179 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,742.72 | 1,052 | BKC9SX3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,679.75 | 5,525 | BRK0149 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,656.24 | 1,387 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,489.91 | 1,147 | BP2NYN2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,341.72 | 1,158 | BQV0J03 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,914.07 | 7,136 | BMYTJP4 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,912.44 | 1,711 | BKDQKM6 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,827.29 | 7,230 | BNR5QT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,517.07 | 4,151 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,700.54 | 8,012 | BNNXX52 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,664.56 | 3,454 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,388.80 | 2,743 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,375.70 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,319.70 | 2,541 | BMTX3D7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,515.35 | 2,105 | BKTV702 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,071.28 | 804 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,760.84 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,531.35 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 36.14% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 26,723,250 | -- | 4,440 | -- |
| 28.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,210,075 | -- | 3,524 | -- |
| 24.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,465,525 | -- | 3,068 | -- |
| 21.48% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,883,481 | -- | 2,639 | -- |
| 20.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 15,125,119 | -- | 2,513 | -- |
| 5.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,809,869 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $22,345,677.26 | 22,345,677 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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