BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.67% | 24.99% | 47.98% | 51.34% | 69.14% | 43.98% | 6.41% | 12.60% | 18.47% | 04/07/2010 |
| BIB Market Price | 4.40% | 24.85% | 47.78% | 51.20% | 68.94% | 43.92% | 6.39% | 12.57% | 18.46% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -0.91% | 14.69% | 41.74% | 44.83% | 94.28% | 35.26% | 4.58% | 9.38% | 18.26% | 04/07/2010 |
| BIB NAV | -1.01% | 14.41% | 41.46% | 44.59% | 93.99% | 35.10% | 4.57% | 9.35% | 18.24% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $97,032,160
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/05/2026- NAV
- NAV Change
- Market Price $112.66
- Market Price Change $-12.45
- Trading Volume (M) 35,994
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $97,032,160
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/05/2026- NAV
- NAV Change
- Market Price $112.66
- Market Price Change $-12.45
- Trading Volume (M) 35,994
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2027. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2026
Holdings
as of 11/05/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.89% | GILD | GILEAD SCIENCES INC | -- | $5,783,343.41 | 34,513 | 2369174 |
| 5.51% | AMGN | AMGEN INC | -- | $5,407,829.72 | 11,749 | 2023607 |
| 5.13% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,031,687.50 | 9,275 | 2931034 |
| 4.06% | MRNA | MODERNA INC | -- | $3,985,297.30 | 16,505 | BGSXTS3 |
| 3.85% | REGN | REGENERON PHARMACEUTICALS | -- | $3,775,024.90 | 4,181 | 2730190 |
| 1.60% | RVMD | REVOLUTION MEDICINES INC | -- | $1,574,156.65 | 8,861 | BL71K91 |
| 1.52% | BIIB | BIOGEN INC | -- | $1,490,168.37 | 6,109 | 2455965 |
| 1.32% | ILMN | ILLUMINA INC | -- | $1,298,544.00 | 6,243 | 2613990 |
| 1.27% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $1,243,828.56 | 18,408 | BMVP7Y0 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $1,093,583.06 | 29,863 | BMW4NZ9 |
| 1.03% | ARGX | ARGENX SE - ADR | -- | $1,009,300.56 | 1,128 | BDVLM39 |
| 1.02% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,003,587.28 | 1,774 | 2430412 |
| 1.01% | INCY | INCYTE CORP | -- | $988,923.80 | 8,380 | 2471950 |
| 1.00% | INSM | INSMED INC | -- | $981,885.28 | 9,028 | 2614487 |
| 0.92% | VTRS | VIATRIS INC | -- | $900,809.42 | 47,486 | BMWS3X9 |
| 0.88% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $866,643.12 | 5,532 | B00FWN1 |
| 0.87% | GH | GUARDANT HEALTH INC | -- | $851,229.64 | 5,548 | BFXC911 |
| 0.75% | MEDP | MEDPACE HOLDINGS INC | -- | $732,766.92 | 1,154 | BDCBC61 |
| 0.72% | EXEL | EXELIXIS INC | -- | $703,865.24 | 10,244 | 2576941 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $671,311.52 | 4,202 | 2623911 |
| 0.66% | ASND | ASCENDIS PHARMA A/S | -- | $645,030.25 | 2,545 | BWXJHM8 |
| 0.63% | BBIO | BRIDGEBIO PHARMA INC | -- | $615,624.03 | 8,289 | BK1KWG8 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $609,899.56 | 2,683 | B4Q5ZN4 |
| 0.59% | HALO | HALOZYME THERAPEUTICS INC | -- | $577,051.28 | 4,693 | 2975098 |
| 0.58% | ONC | BEONE MEDICINES LTD-ADR | -- | $573,904.50 | 1,482 | BYYWPW6 |
| 0.52% | TEM | TEMPUS AI INC-CL A | -- | $510,687.93 | 7,251 | BSLSJJ0 |
| 0.48% | SMMT | SUMMIT THERAPEUTICS INC | -- | $468,000.39 | 32,981 | BMTVQS7 |
| 0.46% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $449,128.36 | 8,003 | 2437071 |
| 0.45% | KYMR | KYMERA THERAPEUTICS INC | -- | $440,348.44 | 3,437 | BMPRZV5 |
| 0.43% | SNY | SANOFI-ADR | -- | $418,061.92 | 8,912 | 2964557 |
| 0.42% | BNTX | BIONTECH SE-ADR | -- | $411,011.82 | 4,787 | BK6H543 |
| 0.39% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $382,495.60 | 956 | BD59BS7 |
| 0.39% | PCVX | VAXCYTE INC | -- | $380,931.84 | 6,152 | BKPVGH6 |
| 0.37% | KRYS | KRYSTAL BIOTECH INC | -- | $367,506.00 | 1,224 | BD6JX35 |
| 0.37% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $361,820.50 | 2,675 | BDCBCD8 |
| 0.36% | SYRE | SPYRE THERAPEUTICS INC | -- | $352,070.55 | 3,645 | BQBBDY8 |
| 0.36% | IBRX | IMMUNITYBIO INC | -- | $350,966.16 | 43,816 | BNSP0B8 |
| 0.34% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $335,566.40 | 5,840 | BYQBFJ8 |
| 0.34% | TWST | TWIST BIOSCIENCE CORP | -- | $330,833.23 | 2,743 | BGKG6G7 |
| 0.33% | CYTK | CYTOKINETICS INC | -- | $319,301.40 | 5,748 | BBBSBJ5 |
| 0.31% | ALKS | ALKERMES PLC | -- | $308,929.44 | 6,936 | B3P6D26 |
| 0.31% | CAI | CARIS LIFE SCIENCES INC | -- | $304,108.49 | 11,683 | BT18HP9 |
| 0.31% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $303,028.86 | 1,154 | BQ721R4 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $298,886.92 | 2,846 | BF2YWG4 |
| 0.29% | TXG | 10X GENOMICS INC-CLASS A | -- | $288,558.20 | 4,970 | BKS3RS7 |
| 0.29% | AXSM | AXSOME THERAPEUTICS INC | -- | $281,146.80 | 2,166 | BYZR4X4 |
| 0.29% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $280,080.00 | 14,400 | BFNF1D6 |
| 0.27% | IONS | IONIS PHARMACEUTICALS INC | -- | $266,594.80 | 6,871 | BDJ0LS6 |
| 0.27% | ORKA | ORUKA THERAPEUTICS INC | -- | $262,806.74 | 2,737 | BKVF0J2 |
| 0.26% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $251,154.90 | 2,685 | BJDX8Y8 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $246,376.00 | 824 | 2501578 |
| 0.25% | IMVT | IMMUNOVANT INC | -- | $242,422.21 | 8,539 | BJRFSB7 |
| 0.24% | CGON | CG ONCOLOGY INC | -- | $237,492.00 | 3,665 | BRBCSP4 |
| 0.24% | KOD | KODIAK SCIENCES INC | -- | $236,469.96 | 2,598 | BFXC933 |
| 0.23% | SUPN | SUPERNUS INC | -- | $229,429.20 | 8,580 | BTZRLN8 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $229,092.50 | 5,035 | BFZQ0L8 |
| 0.23% | PTCT | PTC THERAPEUTICS INC | -- | $226,627.17 | 3,451 | B17VCN9 |
| 0.22% | GRAL | GRAIL INC | -- | $220,033.11 | 1,847 | BSLSSX7 |
| 0.22% | COGT | COGENT BIOSCIENCES INC | -- | $212,206.92 | 7,174 | BLR6XK8 |
| 0.22% | GMAB | GENMAB A/S -SP ADR | -- | $211,434.66 | 4,009 | BBC9WC7 |
| 0.20% | ABVX | ABIVAX SA-ADR | -- | $198,989.70 | 2,364 | BLC89B2 |
| 0.20% | CRSP | CRISPR THERAPEUTICS AG | -- | $194,142.88 | 3,998 | BDHF4K6 |
| 0.20% | ERAS | ERASCA INC | -- | $191,884.20 | 14,460 | BNLYBF3 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $190,446.39 | 3,897 | BLFGJD5 |
| 0.18% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $177,024.34 | 6,598 | BJ5FZ74 |
| 0.18% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $176,414.98 | 1,997 | BRXB0C0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $174,526.30 | 4,490 | BKY5JZ8 |
| 0.17% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $168,649.80 | 5,555 | BV2DHY6 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $154,020.00 | 9,060 | BN2R582 |
| 0.15% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $151,292.52 | 7,123 | 2713317 |
| 0.15% | XENE | XENON PHARMACEUTICALS INC | -- | $150,870.72 | 4,004 | BRJ3GY4 |
| 0.15% | ABCL | ABCELLERA BIOLOGICS INC | -- | $149,108.61 | 13,397 | BL53SR3 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $145,484.77 | 6,971 | BP2P6L0 |
| 0.15% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $144,946.98 | 18,727 | BF0DMK7 |
| 0.15% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $143,320.18 | 5,189 | BPCK358 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $140,319.00 | 5,197 | BKX9VD3 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $135,668.91 | 3,029 | BMFD115 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $134,019.20 | 7,720 | BN15WD1 |
| 0.13% | DNLI | DENALI THERAPEUTICS INC | -- | $130,329.48 | 6,609 | BD2B4V0 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $128,355.52 | 1,901 | BMH5RL1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $124,531.89 | 1,587 | BMGJZJ8 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $122,324.60 | 9,260 | B9NSBM2 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $122,293.50 | 3,990 | BK0VHF6 |
| 0.11% | BEAM | BEAM THERAPEUTICS INC | -- | $110,464.90 | 4,270 | BK6L288 |
| 0.11% | VCEL | VERICEL CORP | -- | $109,618.26 | 2,117 | BSBMN89 |
| 0.11% | XNCR | XENCOR INC | -- | $104,669.70 | 3,074 | BGCYWN8 |
| 0.10% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $98,597.04 | 7,538 | BLR7H87 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $96,483.86 | 1,991 | BQXJKH2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $94,434.59 | 2,903 | BMZ2X38 |
| 0.10% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $93,354.38 | 4,942 | BP8JSP4 |
| 0.09% | SEPN | SEPTERNA INC | -- | $91,385.50 | 1,930 | BQNKXX2 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $89,787.06 | 2,979 | BL55460 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,155.00 | 5,500 | BFWLC09 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $85,832.32 | 3,808 | BMX9K07 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $84,308.49 | 2,934 | BPCQZY9 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $80,610.95 | 10,565 | 2100362 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $80,448.72 | 3,932 | BRXYZ57 |
| 0.08% | VCYT | VERACYTE INC | -- | $79,752.00 | 3,323 | BFTWZY0 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $78,155.29 | 2,407 | BKSGZN7 |
| 0.08% | REPL | REPLIMUNE GROUP INC | -- | $77,977.90 | 3,895 | BDDVW37 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $77,462.00 | 22,132 | BM9FJ13 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $77,095.92 | 6,996 | BK4PZ38 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $76,728.19 | 4,367 | B8DPDT7 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $75,463.71 | 5,891 | BJH9ZN0 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $74,688.88 | 2,296 | BSRK699 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $69,881.35 | 2,695 | BQB42H3 |
| 0.07% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $69,798.63 | 2,469 | BCBVTX1 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $69,528.69 | 2,667 | BJQ05Z6 |
| 0.07% | PSNL | PERSONALIS INC | -- | $68,653.25 | 4,415 | BJQ0608 |
| 0.07% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $67,100.11 | 1,477 | BS2CR64 |
| 0.07% | NVAX | NOVAVAX INC | -- | $66,689.82 | 6,819 | BJDQXG4 |
| 0.07% | ABSI | ABSCI CORP | -- | $66,622.05 | 7,095 | BN94K69 |
| 0.07% | ANIP | ANI PHARMACEUTICALS INC | -- | $66,139.00 | 950 | BCDWBX6 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $65,229.70 | 4,814 | BYSS4X4 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $64,643.04 | 3,388 | BQS9486 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,302.30 | 5,793 | BYZM6C2 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $63,663.60 | 4,290 | BMVLGP2 |
| 0.06% | ALVO | ALVOTECH SA | -- | $63,622.65 | 13,983 | BPNTJ34 |
| 0.06% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $63,463.32 | 4,076 | BJ62Z18 |
| 0.06% | PGEN | PRECIGEN INC | -- | $62,464.44 | 14,802 | BKM5C84 |
| 0.06% | QURE | UNIQURE NV | -- | $60,256.68 | 2,868 | BJFSR88 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $60,020.16 | 1,648 | B3X26D8 |
| 0.06% | OCUL | OCULAR THERAPEUTIX INC | -- | $58,377.97 | 9,079 | BNZB1X8 |
| 0.06% | INVA | INNOVIVA INC | -- | $57,469.88 | 2,987 | BDDXF67 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $55,835.50 | 1,225 | BDRW1L7 |
| 0.06% | ETON | ETON PHARMACEUTICALS INC | -- | $55,731.30 | 1,182 | BGL0JK3 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $55,702.20 | 3,655 | BP9N0G0 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,092.30 | 13,470 | BNC1BX1 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,386.00 | 1,915 | BLCD809 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $52,332.72 | 2,838 | BP6C0S2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $52,000.33 | 2,021 | BZ7PJQ1 |
| 0.05% | TYRA | TYRA BIOSCIENCES INC | -- | $51,535.63 | 2,467 | BMVNDH9 |
| 0.05% | OMER | OMEROS CORP | -- | $51,090.51 | 2,993 | B4NB858 |
| 0.05% | MNKD | MANNKIND CORP | -- | $49,981.68 | 13,293 | BF081J4 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $48,810.24 | 608 | BNSP8K3 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $48,626.28 | 1,758 | BNFWZS4 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $47,060.48 | 1,984 | BR3T9B6 |
| 0.05% | VOR | VOR BIOPHARMA INC | -- | $45,642.36 | 2,446 | BRJJYT3 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $43,236.16 | 5,536 | BMC3HS7 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $43,194.60 | 1,263 | BKLCWZ3 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $42,996.80 | 6,160 | BMCWKZ2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $41,629.20 | 1,842 | BD9GVY0 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $40,599.68 | 2,528 | BMFX8Y7 |
| 0.04% | HROW | HARROW INC | -- | $40,362.00 | 1,550 | BHNDW86 |
| 0.04% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $38,315.96 | 1,943 | BL5B6Z1 |
| 0.04% | SVRA | SAVARA INC | -- | $37,208.10 | 8,495 | BYXGN81 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $36,379.65 | 4,285 | BKVDFF7 |
| 0.04% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $36,151.75 | 3,527 | BP7KZP7 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $35,288.12 | 772 | BQD3J33 |
| 0.04% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $34,594.04 | 3,692 | BN7Q7R7 |
| 0.03% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $33,865.36 | 1,346 | BX7RSN3 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $33,840.94 | 3,478 | BYP80F1 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $33,784.70 | 3,970 | BFYQFJ2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $33,366.10 | 7,498 | BPBJFM7 |
| 0.03% | ANNX | ANNEXON INC | -- | $31,391.19 | 7,838 | BMVV9R5 |
| 0.03% | ALMS | ALUMIS INC | -- | $31,303.35 | 5,351 | BPLQG36 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $31,227.93 | 12,851 | B4N8MH9 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $30,868.80 | 872 | BL95N25 |
| 0.03% | ARDX | ARDELYX INC | -- | $30,802.98 | 10,302 | BN89V40 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $30,568.80 | 2,168 | BQS7491 |
| 0.03% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,020.60 | 8,180 | BZ0QMB7 |
| 0.03% | OABI | OMNIAB INC | -- | $29,033.13 | 6,011 | BN13S71 |
| 0.03% | SANA | SANA BIOTECHNOLOGY INC | -- | $28,959.84 | 12,376 | BMFJJ97 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $28,738.80 | 2,661 | BM90J52 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,528.93 | 6,831 | B3MZ6K5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,395.94 | 4,433 | BQHN6C7 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $27,179.58 | 4,287 | BP81R42 |
| 0.03% | WVE | WAVE LIFE SCIENCES INC | -- | $26,230.12 | 8,146 | C08GM13 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,851.15 | 2,455 | BLFBZ32 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $25,695.00 | 2,284 | BKLXFX5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,430.52 | 3,163 | BP0TQC5 |
| 0.03% | GERN | GERON CORP | -- | $25,236.56 | 26,562 | 2370381 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,025.96 | 2,588 | BMFK3H6 |
| 0.03% | KURA | KURA ONCOLOGY INC | -- | $25,010.40 | 3,678 | BYZD465 |
| 0.03% | AVBP | ARRIVENT BIOPHARMA INC | -- | $24,936.97 | 2,039 | BMGTLY5 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $24,457.68 | 3,618 | BMZ4LN0 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $23,219.52 | 2,546 | BP2NYN2 |
| 0.02% | BCAX | BICARA THERAPEUTICS INC | -- | $22,399.65 | 2,735 | BQB42F1 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,966.85 | 6,085 | BYV2W40 |
| 0.02% | NGNE | NEUROGENE INC | -- | $21,212.55 | 827 | BS2F741 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $20,849.18 | 2,134 | B7F2TY6 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $20,639.40 | 615 | B292NQ7 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,140.02 | 2,729 | BZ0G875 |
| 0.02% | CTMX | CYTOMX THERAPEUTICS INC | -- | $19,277.12 | 9,008 | BYWVTY5 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,991.74 | 5,189 | BYVQJ96 |
| 0.02% | EOLS | EVOLUS INC | -- | $18,550.35 | 2,730 | BDRJH21 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,704.65 | 2,703 | BDZ30Q0 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $17,493.60 | 2,220 | BP7L561 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $16,992.60 | 3,345 | BJLKVS6 |
| 0.02% | CRMD | CORMEDIX INC | -- | $16,851.06 | 3,222 | BJ0LT31 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,742.58 | 2,122 | B91XRN2 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,384.95 | 2,385 | B2Q9833 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,189.95 | 6,349 | BZ8FPH3 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,842.74 | 8,042 | BFY7DC4 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $15,691.36 | 808 | BPBPCG8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,568.47 | 14,283 | BFZNYB7 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $15,195.00 | 1,013 | BTNMG41 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,003.70 | 5,086 | BKX9NQ0 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $13,993.52 | 3,316 | BLN9Z50 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $13,965.70 | 2,485 | BPRB2N7 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,136.32 | 1,204 | B9L5200 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $11,999.22 | 1,362 | BPRBTY7 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $11,787.77 | 2,557 | BSMLR16 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $11,606.72 | 3,154 | BJDX8Z9 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,052.47 | 4,539 | BDFKQ07 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,998.00 | 1,175 | BKC9SX3 |
| 0.01% | SPRY | ARS PHARMACEUTICALS INC | -- | $10,896.80 | 4,112 | BMCR7V2 |
| 0.01% | BIOA | BIOAGE LABS INC | -- | $10,509.38 | 1,897 | BT9K6D8 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,449.18 | 8,293 | BFMLGR4 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $10,016.00 | 1,565 | 2517058 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,964.40 | 4,295 | BMXNGZ6 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $9,853.76 | 3,392 | BQ6C357 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $9,623.25 | 8,225 | BNR5QT9 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,011.38 | 2,674 | BMVBZF5 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $8,975.00 | 2,500 | B12W3P6 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $8,971.52 | 7,009 | BK5MWR1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,878.88 | 4,208 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $8,823.87 | 2,971 | 2107437 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,749.00 | 820 | BM7V485 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,325.50 | 1,610 | BP81RK8 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $7,270.65 | 2,265 | BRCFFK6 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,128.81 | 12,186 | BM8NHS1 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,723.36 | 1,932 | BKDQKM6 |
| 0.01% | PEPG | PEPGEN INC | -- | $6,644.48 | 2,864 | BMTX3D7 |
| 0.01% | SION | SIONNA THERAPEUTICS INC | -- | $6,130.32 | 1,869 | BQKXDX4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,552.89 | 3,449 | BLBR8D5 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,185.95 | 3,143 | BPTK6Z2 |
| -- | CHRS | COHERUS ONCOLOGY INC | -- | $4,783.97 | 6,388 | BRK0149 |
| -- | FHTX | FOGHORN THERAPEUTICS INC | -- | $4,676.78 | 2,455 | BMF7DT9 |
| -- | CDXS | CODEXIS INC | -- | $4,617.54 | 4,527 | B5LL2C2 |
| -- | HUMA | HUMACYTE INC | -- | $4,542.32 | 11,485 | BMYTJP4 |
| -- | VYGR | VOYAGER THERAPEUTICS INC | -- | $4,380.84 | 2,547 | BY7RB53 |
| -- | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $4,254.63 | 3,833 | BYTYP72 |
| -- | NBP | NOVABRIDGE BIOSCIENCES | -- | $4,214.49 | 4,641 | BKRRKY7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,942.50 | 2,375 | BKTV702 |
| -- | LENZ | LENZ THERAPEUTICS INC | -- | $3,909.99 | 1,299 | BQV0J03 |
| -- | NMRA | NEUMORA THERAPEUTICS INC | -- | $3,783.02 | 7,768 | BN4JN37 |
| -- | TNYA | TENAYA THERAPEUTICS INC | -- | $2,929.32 | 9,270 | BNNXX52 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,463.31 | 4,772 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $2,383.26 | 253 | C0BCTT5 |
| -- | CRBU | CARIBOU BIOSCIENCES INC | -- | $1,827.31 | 4,432 | BNYJR68 |
| -- | EYPT | EYEPOINT INC | -- | $1,268.43 | 3,564 | BMGS7L1 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $1,004.55 | 905 | BTXQTX3 |
| -- | -- | COHERUS ONCOLOGY INC COMMON STOCK USD | -- | $00.00 | 5,356 | -- |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 36.72% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 36,039,806 | -- | 5,080 | -- |
| 33.67% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 33,045,948 | -- | 4,658 | -- |
| 23.98% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 23,539,385 | -- | 3,318 | -- |
| 19.07% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 18,722,254 | -- | 2,639 | -- |
| 18.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 17,828,353 | -- | 2,513 | -- |
| 4.55% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,462,409 | -- | 629 | -- |
| -- | IQMM | PROSHARES GENIUS MONEY MARKET ETF | -- | $17,018,700.00 | 170,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $18,333,172.24 | 18,333,172 | -- |
Index
as of 9/30/2026
- Total Number of Holdings245
- Price/Book Ratio6.08
- Dividend Yield ( % )0.49
- Avg. Index Market Capitalization$7.91 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: Why hedge?—A tool for managing risk
Periods of uncertainty often make investors want to reduce risk in their portfolios. A hedging strategy may help investors manage risk while remaining invested for long-term growth.
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