BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View fund details
Documents & Downloads
ETF & Index
Prospectus & Regulatory
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 12/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/21/2026- NAV $85.46
- NAV Change $+3.94
- Market Price $85.43
- Market Price Change $+3.95
- Trading Volume (M) 21,748
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/21/2026- NAV $85.46
- NAV Change $+3.94
- Market Price $85.43
- Market Price Change $+3.95
- Trading Volume (M) 21,748
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 1/20/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.99% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,177,640.96 | 11,712 | 2931034 |
| 5.80% | GILD | GILEAD SCIENCES INC | -- | $5,009,793.84 | 40,356 | 2369174 |
| 5.63% | AMGN | AMGEN INC | -- | $4,865,700.00 | 14,700 | 2023607 |
| 4.10% | REGN | REGENERON PHARMACEUTICALS | -- | $3,539,020.94 | 4,823 | 2730190 |
| 2.54% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,195,397.75 | 6,175 | B00FWN1 |
| 1.88% | INSM | INSMED INC | -- | $1,628,559.60 | 9,960 | 2614487 |
| 1.31% | BIIB | BIOGEN INC | -- | $1,133,018.38 | 6,851 | 2455965 |
| 1.27% | ARGX | ARGENX SE - ADR | -- | $1,100,300.76 | 1,359 | BDVLM39 |
| 1.22% | ILMN | ILLUMINA INC | -- | $1,050,205.12 | 7,136 | 2613990 |
| 1.21% | RVMD | REVOLUTION MEDICINES INC | -- | $1,049,234.16 | 9,028 | BL71K91 |
| 1.09% | UTHR | UNITED THERAPEUTICS CORP | -- | $941,288.77 | 2,011 | 2430412 |
| 1.09% | INCY | INCYTE CORP | -- | $940,820.16 | 9,168 | 2471950 |
| 0.92% | MEDP | MEDPACE HOLDINGS INC | -- | $793,360.80 | 1,317 | BDCBC61 |
| 0.91% | MRNA | MODERNA INC | -- | $784,492.00 | 18,244 | BGSXTS3 |
| 0.90% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $779,806.41 | 19,949 | BMVP7Y0 |
| 0.86% | ROIV | ROIVANT SCIENCES LTD | -- | $746,528.28 | 32,486 | BMW4NZ9 |
| 0.80% | BBIO | BRIDGEBIO PHARMA INC | -- | $694,632.81 | 8,999 | BK1KWG8 |
| 0.80% | GH | GUARDANT HEALTH INC | -- | $694,044.54 | 6,042 | BFXC911 |
| 0.79% | VTRS | VIATRIS INC | -- | $680,930.76 | 53,786 | BMWS3X9 |
| 0.72% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $626,418.24 | 4,656 | 2623911 |
| 0.72% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $618,067.86 | 2,867 | BV9G6B8 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $586,436.92 | 7,564 | BDJ0LS6 |
| 0.65% | SNY | SANOFI-ADR | -- | $565,254.92 | 12,358 | 2964557 |
| 0.65% | SMMT | SUMMIT THERAPEUTICS INC | -- | $558,325.90 | 34,765 | BMTVQS7 |
| 0.63% | EXEL | EXELIXIS INC | -- | $548,256.94 | 12,523 | 2576941 |
| 0.62% | TEM | TEMPUS AI INC | -- | $539,114.94 | 8,073 | BSLSJJ0 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $536,256.90 | 1,062 | BD59BS7 |
| 0.59% | RNA | AVIDITY BIOSCIENCES INC | -- | $509,898.92 | 7,036 | BMWHPY1 |
| 0.58% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $505,213.32 | 8,972 | 2437071 |
| 0.58% | BNTX | BIONTECH SE-ADR | -- | $498,348.76 | 4,721 | BK6H543 |
| 0.57% | ONC | BEONE MEDICINES LTD-ADR | -- | $491,391.60 | 1,470 | BYYWPW6 |
| 0.55% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $476,443.44 | 2,838 | B4Q5ZN4 |
| 0.50% | AXSM | AXSOME THERAPEUTICS INC | -- | $434,313.00 | 2,354 | BYZR4X4 |
| 0.48% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $413,614.08 | 6,336 | BYQBFJ8 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $386,801.56 | 5,492 | 2975098 |
| 0.44% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $378,525.44 | 1,168 | BQ721R4 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $372,092.74 | 1,354 | BD6JX35 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $364,183.80 | 5,710 | BBBSBJ5 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $357,407.82 | 3,374 | BMVBZD3 |
| 0.40% | CAI | CARIS LIFE SCIENCES INC | -- | $346,133.52 | 13,176 | BT18HP9 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $327,523.04 | 2,756 | BLC89B2 |
| 0.37% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $319,670.44 | 3,116 | BF2YWG4 |
| 0.34% | IBRX | IMMUNITYBIO INC | -- | $298,060.56 | 45,997 | BNSP0B8 |
| 0.34% | PCVX | VAXCYTE INC | -- | $290,489.76 | 6,113 | BKPVGH6 |
| 0.33% | COGT | COGENT BIOSCIENCES INC | -- | $286,122.90 | 7,171 | BLR6XK8 |
| 0.33% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $283,982.40 | 3,120 | BQS9486 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $273,939.43 | 3,749 | B17VCN9 |
| 0.29% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $246,873.77 | 4,433 | BDD19F8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $244,824.25 | 7,711 | B3P6D26 |
| 0.28% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $243,502.98 | 2,919 | BDCBCD8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $234,377.55 | 4,455 | BDHF4K6 |
| 0.26% | KYMR | KYMERA THERAPEUTICS INC | -- | $228,950.40 | 3,360 | BMPRZV5 |
| 0.26% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $220,536.00 | 2,400 | BJDX8Y8 |
| 0.25% | IMVT | IMMUNOVANT INC | -- | $214,034.32 | 8,188 | BJRFSB7 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $213,230.84 | 4,766 | BFZQ0L8 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $210,104.44 | 2,561 | BM9HHL5 |
| 0.24% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $207,717.29 | 7,901 | 2713317 |
| 0.24% | FOLD | AMICUS THERAPEUTICS INC | -- | $206,178.48 | 14,408 | B19FQ48 |
| 0.24% | CGON | CG ONCOLOGY INC | -- | $206,017.23 | 3,767 | BRBCSP4 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $195,684.40 | 14,680 | BFNF1D6 |
| 0.23% | ADMA | ADMA BIOLOGICS INC | -- | $195,495.26 | 11,114 | B9NSBM2 |
| 0.23% | ACLX | ARCELLX INC | -- | $194,859.00 | 2,700 | BPCJ1Q2 |
| 0.22% | INDV | INDIVIOR PLC | -- | $192,164.40 | 5,832 | BP0BQQ5 |
| 0.21% | GRAL | GRAIL INC | -- | $184,384.20 | 1,820 | BSLSSX7 |
| 0.21% | LGND | LIGAND PHARMACEUTICALS | -- | $180,638.64 | 919 | 2501578 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $171,610.95 | 5,295 | BP8JSP4 |
| 0.18% | VCYT | VERACYTE INC | -- | $153,919.48 | 3,692 | BFTWZY0 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $153,892.06 | 4,207 | BMDJ0C9 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $149,778.90 | 3,610 | BRJ3GY4 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $147,976.40 | 5,720 | BKX9VD3 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $146,743.14 | 4,739 | BK6L288 |
| 0.17% | IDYA | IDEAYA BIOSCIENCES INC | -- | $146,360.50 | 4,094 | BK0VHF6 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $142,041.12 | 4,944 | BKY5JZ8 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $140,583.26 | 1,982 | BMH5RL1 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $133,817.55 | 2,985 | BL55460 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $133,417.96 | 2,678 | B72ZBG4 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $130,536.00 | 1,764 | BMGJZJ8 |
| 0.15% | ERAS | ERASCA INC | -- | $129,972.69 | 13,249 | BNLYBF3 |
| 0.15% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $127,323.75 | 7,125 | BJ5FZ74 |
| 0.14% | SYRE | SPYRE THERAPEUTICS INC | -- | $122,203.79 | 3,623 | BQBBDY8 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $120,957.23 | 5,909 | BYTQ6X1 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $120,062.97 | 6,849 | BD2B4V0 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $119,996.10 | 5,442 | BKS3RS7 |
| 0.14% | TWST | TWIST BIOSCIENCE CORP | -- | $118,952.40 | 2,856 | BGKG6G7 |
| 0.14% | ALMS | ALUMIS INC | -- | $118,312.40 | 4,540 | BPLQG36 |
| 0.14% | MLYS | MINERALYS THERAPEUTICS INC | -- | $118,013.28 | 3,696 | BP9N0G0 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $116,733.32 | 4,178 | BLFGJD5 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $113,973.30 | 9,954 | BNZB1X8 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $110,588.60 | 6,670 | BN15WD1 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $107,892.74 | 7,807 | BYZG9R0 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $105,652.80 | 24,012 | BM9FJ13 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $103,254.60 | 4,505 | BLB0YQ9 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $102,948.72 | 4,893 | B8DPDT7 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $101,948.15 | 4,505 | BJ62Z18 |
| 0.12% | MAZE | MAZE THERAPEUTICS INC | -- | $99,631.98 | 2,247 | BSRK699 |
| 0.11% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $98,089.12 | 3,671 | BMZ4LN0 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $96,597.90 | 2,690 | BKSGZN7 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $92,087.44 | 3,932 | BMX9K07 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,239.51 | 6,169 | BFWLC09 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $90,464.58 | 2,097 | BQXJKH2 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $89,972.73 | 1,049 | BCDWBX6 |
| 0.10% | ARDX | ARDELYX INC | -- | $88,052.72 | 11,347 | BN89V40 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $86,532.27 | 2,109 | BRXB0C0 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $86,348.16 | 4,734 | BMVLGP2 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $85,989.12 | 5,484 | BRJZSK0 |
| 0.10% | VCEL | VERICEL CORP | -- | $85,716.98 | 2,362 | BSBMN89 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $85,530.90 | 2,730 | BBC9WC7 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $84,868.40 | 5,128 | BPCK358 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $83,380.84 | 2,084 | BQKXDX4 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $82,726.65 | 3,495 | BPCQZY9 |
| 0.10% | HROW | HARROW INC | -- | $82,555.60 | 1,730 | BHNDW86 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $82,113.57 | 4,059 | BN7Q7R7 |
| 0.09% | MNKD | MANNKIND CORP | -- | $78,803.46 | 14,354 | BF081J4 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $78,675.39 | 6,289 | BP2P6L0 |
| 0.09% | PHVS | PHARVARIS NV | -- | $78,394.11 | 2,991 | BMZ2X38 |
| 0.09% | UPB | UPSTREAM BIO INC | -- | $78,244.00 | 2,524 | BRCFFK6 |
| 0.09% | -- | DEFINIUM THERAPEUTICS INC COMMON STOCK USD 0 | -- | $77,188.00 | 4,600 | -- |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $76,596.24 | 2,667 | BJQ05Z6 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $75,133.03 | 2,261 | BKVF0J2 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $74,955.55 | 2,771 | BMFD115 |
| 0.09% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $74,678.08 | 3,488 | BYP80F1 |
| 0.09% | RAPT | RAPT THERAPEUTICS INC | -- | $74,495.58 | 1,294 | BTJZB49 |
| 0.09% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $74,322.04 | 3,041 | BP7KZP7 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $73,538.92 | 2,492 | BMVNDH9 |
| 0.08% | PGEN | PRECIGEN INC | -- | $72,702.79 | 16,561 | BKM5C84 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $72,649.64 | 2,723 | BCBVTX1 |
| 0.08% | ALVO | ALVOTECH SA | -- | $72,505.28 | 14,618 | BPNTJ34 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $70,405.20 | 1,476 | BX7RSN3 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,448.79 | 5,413 | BYZM6C2 |
| 0.08% | INVA | INNOVIVA INC | -- | $68,268.60 | 3,492 | BDDXF67 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $68,263.30 | 4,315 | BRXYZ57 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $68,055.44 | 5,229 | BYSS4X4 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $67,893.21 | 2,037 | BLCD809 |
| 0.08% | KOD | KODIAK SCIENCES INC | -- | $65,987.28 | 2,477 | BFXC933 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $65,579.44 | 9,832 | 2100362 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $65,299.85 | 16,961 | BWJDYK1 |
| 0.08% | QURE | UNIQURE NV | -- | $65,161.60 | 2,909 | BJFSR88 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $62,394.96 | 5,988 | BJH9ZN0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $62,229.80 | 7,589 | BJDQXG4 |
| 0.07% | EYPT | EYEPOINT INC | -- | $60,155.34 | 3,871 | BMGS7L1 |
| 0.07% | RLAY | RELAY THERAPEUTICS INC | -- | $60,013.59 | 8,099 | BN2R582 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $59,749.53 | 1,293 | BDRW1L7 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,354.88 | 12,792 | BNC1BX1 |
| 0.07% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $58,962.28 | 7,748 | BLR7H87 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $58,152.64 | 13,979 | BL53SR3 |
| 0.07% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $58,067.45 | 4,795 | BLB0YH0 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $57,731.31 | 2,223 | BR3T9B6 |
| 0.07% | SANA | SANA BIOTECHNOLOGY INC | -- | $56,970.62 | 12,439 | BMFJJ97 |
| 0.07% | SVRA | SAVARA INC | -- | $56,726.94 | 9,502 | BYXGN81 |
| 0.07% | SEPN | SEPTERNA INC | -- | $56,519.73 | 2,091 | BQNKXX2 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $55,692.18 | 1,363 | BKLCWZ3 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $55,688.70 | 2,146 | BNFWZS4 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $52,847.76 | 4,548 | BKVDFF7 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $52,471.44 | 2,513 | BQB42H3 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $49,499.10 | 679 | BNSP8K3 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $49,222.08 | 5,697 | B8K7T65 |
| 0.06% | TBPH | THERAVANCE BIOPHARMA INC | -- | $48,313.72 | 2,366 | BMNDK09 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $48,237.20 | 4,616 | BMCR7V2 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $47,105.35 | 3,329 | BJLKVS6 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,248.16 | 3,332 | BMG99Y1 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $45,627.75 | 2,897 | BP6C0S2 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $45,427.92 | 18,618 | BF0DMK7 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $42,917.28 | 1,928 | BMGTLY5 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $42,803.20 | 2,560 | BQB42F1 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $42,567.99 | 7,927 | BYWVTY5 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $42,255.38 | 2,186 | BZ7PJQ1 |
| 0.05% | XNCR | XENCOR INC | -- | $42,154.40 | 3,335 | BGCYWN8 |
| 0.05% | ANNX | ANNEXON INC | -- | $41,734.00 | 6,775 | BMVV9R5 |
| 0.05% | OMER | OMEROS CORP | -- | $40,592.86 | 3,311 | B4NB858 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $39,231.40 | 955 | BL95N25 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $38,982.00 | 6,497 | BK4PZ38 |
| 0.05% | PSNL | PERSONALIS INC | -- | $38,940.33 | 4,147 | BJQ0608 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $38,773.70 | 2,009 | B3X26D8 |
| 0.04% | GERN | GERON CORP | -- | $38,753.00 | 29,810 | 2370381 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,540.70 | 2,290 | BQS7491 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,857.62 | 9,003 | BZ0QMB7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $36,938.35 | 2,809 | BMFX8Y7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $36,162.22 | 2,362 | BD06CS0 |
| 0.04% | ARVN | ARVINAS INC | -- | $36,077.97 | 2,999 | BDZ30Q0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $35,689.68 | 1,674 | BT9K6D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,950.40 | 4,064 | BYZD465 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $34,716.40 | 7,580 | B3MZ6K5 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $34,567.48 | 1,828 | BD9GVY0 |
| 0.04% | RGNX | REGENXBIO INC | -- | $33,332.40 | 2,364 | BZ0G875 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $33,273.64 | 14,099 | B4N8MH9 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $32,831.60 | 8,440 | BPBJFM7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $32,263.96 | 11,164 | BBNBTD2 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $32,164.00 | 4,400 | BMC3HS7 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $30,816.32 | 848 | BQD3J33 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,990.33 | 2,759 | BM90J52 |
| 0.03% | IVVD | INVIVYD INC | -- | $28,987.84 | 12,941 | BM8NHS1 |
| 0.03% | LENZ | LENZ THERAPEUTICS INC | -- | $28,314.18 | 1,461 | BQV0J03 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $28,158.00 | 10,830 | BJ0CK86 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,515.88 | 3,759 | BFYQFJ2 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $26,786.20 | 2,527 | BJDX8Z9 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $26,225.89 | 1,423 | BM7V485 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $25,677.63 | 3,663 | BDDVW37 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $25,395.00 | 6,772 | BMCWKZ2 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,311.52 | 3,679 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,137.00 | 2,660 | BMFK3H6 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $24,742.08 | 3,408 | BQ6C357 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,713.58 | 2,629 | BLFBZ32 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $23,684.90 | 991 | BTNMG41 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,254.50 | 2,514 | B91XRN2 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,599.00 | 675 | B292NQ7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,415.80 | 5,060 | BYV2W40 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,869.76 | 3,344 | 2107437 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $21,279.60 | 2,760 | B12W3P6 |
| 0.02% | KMDA | KAMADA LTD | -- | $21,040.14 | 2,694 | B2Q9833 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $21,010.31 | 4,177 | BYTYP72 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $20,612.79 | 4,873 | BFY7DC4 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $20,445.56 | 3,638 | BQHN6C7 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,363.80 | 7,022 | BN94K69 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,330.16 | 2,668 | BKLXFX5 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,825.56 | 5,697 | BYVQJ96 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $19,230.72 | 1,252 | BGL0JK3 |
| 0.02% | PEPG | PEPGEN INC | -- | $19,099.50 | 3,210 | BMTX3D7 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $19,031.60 | 4,855 | BKRRKY7 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $18,956.70 | 1,785 | BP81RK8 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,445.90 | 2,045 | BSMLR16 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,396.56 | 5,054 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,836.52 | 1,348 | B9L5200 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,693.40 | 874 | BPBPCG8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,477.15 | 10,495 | BFZNYB7 |
| 0.02% | AARD | AARDVARK THERAPEUTICS INC | -- | $15,783.84 | 1,017 | BTXQTX3 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $15,567.48 | 4,689 | BZC0D70 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,529.80 | 2,353 | B7F2TY6 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,316.62 | 3,027 | BDRJH21 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,178.88 | 2,564 | BP0TQC5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,741.02 | 2,966 | BP81R42 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,710.37 | 2,641 | BMF7DT9 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,591.61 | 7,803 | BN4JN37 |
| 0.02% | LFCR | LIFECORE BIOMEDICAL INC | -- | $14,437.50 | 1,750 | 2517058 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,430.82 | 3,019 | BMVBZF5 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $14,413.87 | 2,161 | BKDQKM6 |
| 0.02% | VOR | VOR BIOPHARMA INC | -- | $13,851.20 | 787 | BRJJYT3 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,302.56 | 9,368 | BFMLGR4 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,790.40 | 3,997 | BMXNGZ6 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,786.15 | 1,079 | BPRBTY7 |
| 0.01% | OABI | OMNIAB INC | -- | $12,773.70 | 6,723 | BN13S71 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,666.96 | 723 | BS2F741 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,549.12 | 3,648 | BLN9Z50 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $11,573.00 | 3,550 | BPTK6Z2 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,403.60 | 2,193 | BL5B6Z1 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,867.08 | 9,132 | BNR5QT9 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,653.48 | 2,637 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,114.52 | 2,756 | BY7RB53 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,866.68 | 4,526 | BKX9NQ0 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $9,844.05 | 4,495 | BK5MWR1 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,421.70 | 1,327 | BKC9SX3 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,209.18 | 4,559 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,106.00 | 1,450 | BP2NYN2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,919.90 | 8,745 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,749.75 | 5,645 | BRK0149 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,425.00 | 2,500 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,790.98 | 4,218 | B5LL2C2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,386.40 | 2,661 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,194.80 | 4,555 | BNNXX18 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,067.35 | 4,365 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,460.31 | 7,776 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,827.28 | 2,908 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $14.92 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 38.75% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 33,489,712 | -- | 5,789 | -- |
| 30.33% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,212,107 | -- | 4,531 | -- |
| 23.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,693,160 | -- | 3,577 | -- |
| 16.63% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,370,089 | -- | 2,484 | -- |
| 15.39% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 13,299,853 | -- | 2,299 | -- |
| 4.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,661,943 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,908,248.21 | 25,908,248 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More