BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 20.05% | 41.93% | 51.59% | 42.58% | 20.67% | 9.55% | 2.60% | 0.91% | 15.79% | 04/07/2010 |
| BIB Market Price | 20.06% | 42.12% | 51.73% | 42.51% | 20.92% | 9.51% | 2.55% | 0.91% | 15.79% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 8.14% | 30.45% | 24.49% | 18.70% | -4.97% | 8.65% | -2.66% | 0.48% | 14.52% | 04/07/2010 |
| BIB NAV | 8.12% | 30.51% | 24.65% | 18.77% | -5.03% | 8.69% | -2.70% | 0.43% | 14.52% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 12/01/2025- NAV $79.93
- NAV Change $-3.63
- Market Price $79.90
- Market Price Change $-3.78
- Trading Volume (M) 23,938
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 12/01/2025- NAV $79.93
- NAV Change $-3.63
- Market Price $79.90
- Market Price Change $-3.78
- Trading Volume (M) 23,938
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2025
Holdings
as of 12/01/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.40% | AMGN | AMGEN INC | -- | $4,533,165.68 | 13,432 | 2023607 |
| 5.07% | GILD | GILEAD SCIENCES INC | -- | $4,253,453.63 | 34,211 | 2369174 |
| 5.01% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,206,204.80 | 9,883 | 2931034 |
| 4.31% | REGN | REGENERON PHARMACEUTICALS | -- | $3,619,280.75 | 4,825 | 2730190 |
| 3.29% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,759,633.76 | 6,071 | B00FWN1 |
| 2.61% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $2,189,045.16 | 24,183 | 2989044 |
| 2.49% | INSM | INSMED INC | -- | $2,087,039.52 | 9,872 | 2614487 |
| 1.52% | ARGX | ARGENX SE - ADR | -- | $1,278,812.10 | 1,429 | BDVLM39 |
| 1.45% | BIIB | BIOGEN INC | -- | $1,217,259.66 | 6,847 | 2455965 |
| 1.21% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,013,654.40 | 2,112 | 2430412 |
| 1.11% | INCY | INCYTE CORP | -- | $930,502.76 | 9,119 | 2471950 |
| 1.10% | ILMN | ILLUMINA INC | -- | $923,952.16 | 7,178 | 2613990 |
| 0.96% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $805,501.20 | 20,188 | BMVP7Y0 |
| 0.92% | MEDP | MEDPACE HOLDINGS INC | -- | $771,429.76 | 1,312 | BDCBC61 |
| 0.83% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $698,725.28 | 4,631 | 2623911 |
| 0.79% | RVMD | REVOLUTION MEDICINES INC | -- | $661,734.00 | 8,730 | BL71K91 |
| 0.77% | ROIV | ROIVANT SCIENCES LTD | -- | $644,836.02 | 31,891 | BMW4NZ9 |
| 0.76% | BBIO | BRIDGEBIO PHARMA INC | -- | $640,780.06 | 8,927 | BK1KWG8 |
| 0.75% | SNY | SANOFI-ADR | -- | $625,973.40 | 12,532 | 2964557 |
| 0.73% | GH | GUARDANT HEALTH INC | -- | $612,801.28 | 5,824 | BFXC911 |
| 0.73% | IONS | IONIS PHARMACEUTICALS INC | -- | $610,251.57 | 7,443 | BDJ0LS6 |
| 0.72% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $604,945.80 | 1,044 | BD59BS7 |
| 0.71% | SMMT | SUMMIT THERAPEUTICS INC | -- | $598,766.66 | 34,691 | BMTVQS7 |
| 0.71% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $597,759.75 | 2,835 | BV9G6B8 |
| 0.70% | TEM | TEMPUS AI INC | -- | $583,449.39 | 7,877 | BSLSJJ0 |
| 0.69% | VTRS | VIATRIS INC | -- | $582,572.20 | 54,446 | BMWS3X9 |
| 0.65% | EXEL | EXELIXIS INC | -- | $545,958.53 | 12,571 | 2576941 |
| 0.63% | ONC | BEONE MEDICINES LTD-ADR | -- | $526,892.00 | 1,570 | BYYWPW6 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $493,343.95 | 8,965 | 2437071 |
| 0.58% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $487,443.84 | 2,832 | B4Q5ZN4 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $457,538.22 | 4,698 | BK6H543 |
| 0.52% | MRNA | MODERNA INC | -- | $438,987.20 | 18,170 | BGSXTS3 |
| 0.51% | RNA | AVIDITY BIOSCIENCES INC | -- | $428,670.80 | 6,008 | BMWHPY1 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $371,962.20 | 5,462 | 2975098 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $369,087.40 | 5,588 | BBBSBJ5 |
| 0.43% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $363,206.25 | 6,457 | BYQBFJ8 |
| 0.41% | AXSM | AXSOME THERAPEUTICS INC | -- | $347,388.93 | 2,331 | BYZR4X4 |
| 0.40% | MRUS | MERUS NV | -- | $338,860.08 | 3,532 | BZBY005 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $331,391.88 | 3,114 | BMVBZD3 |
| 0.39% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $325,834.08 | 3,102 | BF2YWG4 |
| 0.35% | PTCT | PTC THERAPEUTICS INC | -- | $293,832.00 | 3,710 | B17VCN9 |
| 0.35% | KRYS | KRYSTAL BIOTECH INC | -- | $290,613.61 | 1,351 | BD6JX35 |
| 0.33% | PCVX | VAXCYTE INC | -- | $275,987.76 | 6,063 | BKPVGH6 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $259,394.24 | 6,524 | BLR6XK8 |
| 0.30% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $248,784.20 | 2,905 | BDCBCD8 |
| 0.27% | KYMR | KYMERA THERAPEUTICS INC | -- | $223,245.54 | 3,339 | BMPRZV5 |
| 0.27% | ALKS | ALKERMES PLC | -- | $222,790.10 | 7,709 | B3P6D26 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $221,200.80 | 4,240 | BDHF4K6 |
| 0.26% | ADMA | ADMA BIOLOGICS INC | -- | $215,970.72 | 11,144 | B9NSBM2 |
| 0.25% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $208,308.99 | 5,259 | BP8JSP4 |
| 0.24% | AKRO | AKERO THERAPEUTICS INC | -- | $203,369.16 | 3,736 | BK7Y2V9 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $199,009.50 | 4,398 | BDD19F8 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $195,793.15 | 7,879 | 2713317 |
| 0.23% | INDV | INDIVIOR PLC | -- | $195,787.20 | 5,827 | BP0BQQ5 |
| 0.22% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $188,535.10 | 4,490 | BFZQ0L8 |
| 0.22% | IMVT | IMMUNOVANT INC | -- | $185,185.00 | 8,140 | BJRFSB7 |
| 0.22% | ACLX | ARCELLX INC | -- | $182,025.20 | 2,590 | BPCJ1Q2 |
| 0.22% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $181,422.48 | 983 | BQ721R4 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $180,550.77 | 14,667 | BFNF1D6 |
| 0.21% | LGND | LIGAND PHARMACEUTICALS | -- | $180,227.55 | 915 | 2501578 |
| 0.20% | VCYT | VERACYTE INC | -- | $170,436.86 | 3,674 | BFTWZY0 |
| 0.20% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $169,950.52 | 5,596 | BKX9VD3 |
| 0.20% | GRAL | GRAIL INC | -- | $165,486.68 | 1,684 | BSLSSX7 |
| 0.20% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $164,243.46 | 2,346 | BJDX8Y8 |
| 0.19% | TARS | TARSUS PHARMACEUTICALS INC | -- | $157,620.87 | 1,971 | BMH5RL1 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $156,679.51 | 3,601 | BRJ3GY4 |
| 0.18% | CGON | CG ONCOLOGY INC | -- | $154,013.25 | 3,561 | BRBCSP4 |
| 0.18% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $150,198.37 | 4,501 | BJ62Z18 |
| 0.18% | IRON | DISC MEDICINE INC | -- | $148,721.18 | 1,622 | BMGJZJ8 |
| 0.18% | APGE | APOGEE THERAPEUTICS INC | -- | $148,539.84 | 2,154 | BM9HHL5 |
| 0.17% | TVTX | TRAVERE THERAPEUTICS INC | -- | $146,460.78 | 4,162 | BLFGJD5 |
| 0.17% | FOLD | AMICUS THERAPEUTICS INC | -- | $141,071.00 | 14,395 | B19FQ48 |
| 0.17% | IDYA | IDEAYA BIOSCIENCES INC | -- | $140,396.52 | 4,092 | BK0VHF6 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $136,912.23 | 6,643 | BN15WD1 |
| 0.16% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $133,971.24 | 7,111 | BJ5FZ74 |
| 0.15% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $127,488.66 | 4,478 | BLB0YQ9 |
| 0.15% | MLYS | MINERALYS THERAPEUTICS INC | -- | $126,131.04 | 3,096 | BP9N0G0 |
| 0.15% | APLS | APELLIS PHARMACEUTICALS INC | -- | $125,037.60 | 5,898 | BYTQ6X1 |
| 0.15% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $124,328.40 | 4,920 | BKY5JZ8 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $124,014.64 | 6,829 | BD2B4V0 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $117,069.30 | 2,619 | B72ZBG4 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $113,636.25 | 4,725 | BK6L288 |
| 0.13% | TERN | TERNS PHARMACEUTICALS INC | -- | $112,349.93 | 4,081 | BMDJ0C9 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $105,534.88 | 3,932 | BMX9K07 |
| 0.12% | IBRX | IMMUNITYBIO INC | -- | $101,528.90 | 44,143 | BNSP0B8 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $99,396.99 | 6,147 | BFWLC09 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $98,340.00 | 2,980 | BL55460 |
| 0.12% | AVDL | AVADEL PHARMACEUTICALS | -- | $97,118.28 | 4,534 | BDGMC59 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $96,601.44 | 5,343 | BKS3RS7 |
| 0.11% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $96,208.31 | 2,783 | BQS9486 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $95,379.86 | 2,686 | BKSGZN7 |
| 0.11% | JANX | JANUX THERAPEUTICS INC | -- | $95,375.94 | 2,806 | BMFX8Y7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $95,143.75 | 8,125 | BNZB1X8 |
| 0.11% | VCEL | VERICEL CORP | -- | $91,459.92 | 2,356 | BSBMN89 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $91,365.30 | 3,510 | BPCQZY9 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $90,002.08 | 4,564 | B8DPDT7 |
| 0.11% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $89,579.75 | 3,205 | BMZ4LN0 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $87,008.16 | 19,956 | BM9FJ13 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $85,568.11 | 1,013 | BCDWBX6 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $84,175.34 | 2,819 | BGKG6G7 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $83,087.90 | 2,030 | BRXB0C0 |
| 0.10% | SYRE | SPYRE THERAPEUTICS INC | -- | $80,849.86 | 2,821 | BQBBDY8 |
| 0.09% | MNKD | MANNKIND CORP | -- | $77,806.47 | 14,329 | BF081J4 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $77,000.31 | 2,559 | BJQ05Z6 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $76,919.76 | 4,023 | BN7Q7R7 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $75,696.96 | 2,719 | BCBVTX1 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $75,637.10 | 5,687 | BJH9ZN0 |
| 0.08% | ALVO | ALVOTECH SA | -- | $70,746.28 | 14,617 | BPNTJ34 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $70,293.30 | 1,870 | BLCD809 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $69,902.52 | 9,804 | 2100362 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $68,931.06 | 1,471 | BX7RSN3 |
| 0.08% | HROW | HARROW INC | -- | $68,739.84 | 1,728 | BHNDW86 |
| 0.08% | QURE | UNIQURE NV | -- | $68,072.34 | 2,562 | BJFSR88 |
| 0.07% | ARDX | ARDELYX INC | -- | $62,909.86 | 11,254 | BN89V40 |
| 0.07% | INVA | INNOVIVA INC | -- | $62,273.88 | 2,943 | BDDXF67 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $61,502.06 | 2,161 | BZ7PJQ1 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $61,461.62 | 1,958 | BBC9WC7 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $60,981.28 | 5,221 | BYSS4X4 |
| 0.07% | NRIX | NURIX THERAPEUTICS INC | -- | $60,334.88 | 3,568 | BMVLGP2 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $59,593.95 | 2,171 | BNFWZS4 |
| 0.07% | RLAY | RELAY THERAPEUTICS INC | -- | $59,577.40 | 8,051 | BN2R582 |
| 0.07% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $59,252.64 | 4,161 | BPCK358 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $58,647.96 | 5,476 | BRJZSK0 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,433.77 | 12,739 | BNC1BX1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,071.12 | 7,432 | BYZG9R0 |
| 0.07% | XNCR | XENCOR INC | -- | $54,994.81 | 3,331 | BGCYWN8 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $54,905.10 | 2,766 | BMFD115 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $54,681.29 | 677 | BNSP8K3 |
| 0.07% | CVAC | CUREVAC NV | -- | $54,678.00 | 10,515 | BN4RD42 |
| 0.06% | TNGX | TANGO THERAPEUTICS INC | -- | $54,142.32 | 5,196 | BP2P6L0 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $54,033.48 | 1,308 | BDRW1L7 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $52,968.48 | 1,354 | BKLCWZ3 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $52,745.60 | 4,240 | BRXYZ57 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $52,485.36 | 7,541 | BLR7H87 |
| 0.06% | TYRA | TYRA BIOSCIENCES INC | -- | $51,796.09 | 2,489 | BMVNDH9 |
| 0.06% | NVAX | NOVAVAX INC | -- | $50,743.65 | 7,585 | BJDQXG4 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $50,565.25 | 4,535 | BKVDFF7 |
| 0.06% | PGEN | PRECIGEN INC | -- | $50,233.15 | 13,915 | BKM5C84 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $50,076.63 | 5,697 | B8K7T65 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $49,722.60 | 2,098 | B3X26D8 |
| 0.06% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $49,496.22 | 3,313 | BJLKVS6 |
| 0.06% | RAPP | RAPPORT THERAPEUTICS INC | -- | $48,677.75 | 1,705 | BR3T9B6 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $48,423.85 | 13,955 | BL53SR3 |
| 0.06% | ORKA | ORUKA THERAPEUTICS INC | -- | $48,394.83 | 1,749 | BKVF0J2 |
| 0.06% | SANA | SANA BIOTECHNOLOGY INC | -- | $48,324.00 | 12,081 | BMFJJ97 |
| 0.06% | SVRA | SAVARA INC | -- | $47,140.48 | 8,072 | BYXGN81 |
| 0.06% | KURA | KURA ONCOLOGY INC | -- | $46,366.32 | 4,053 | BYZD465 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,122.72 | 2,352 | BMNDK09 |
| 0.05% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $45,902.94 | 3,219 | BMGS7L1 |
| 0.05% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $45,509.52 | 2,884 | BP7KZP7 |
| 0.05% | ZLAB | ZAI LAB LTD-ADR | -- | $44,392.04 | 2,233 | BD9GVY0 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $43,645.60 | 3,560 | BPQYY97 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $43,381.00 | 4,615 | BMCR7V2 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $42,652.88 | 1,894 | BMGTLY5 |
| 0.05% | NTLA | INTELLIA THERAPEUTICS INC | -- | $42,209.46 | 5,013 | BYZM6C2 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $41,994.74 | 4,783 | BLB0YH0 |
| 0.05% | ARVN | ARVINAS INC | -- | $40,496.49 | 3,429 | BDZ30Q0 |
| 0.05% | LENZ | LENZ THERAPEUTICS INC | -- | $40,492.80 | 1,332 | BQV0J03 |
| 0.05% | PSNL | PERSONALIS INC | -- | $40,084.88 | 4,141 | BJQ0608 |
| 0.05% | ERAS | ERASCA INC | -- | $39,741.00 | 13,247 | BNLYBF3 |
| 0.05% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $39,603.88 | 838 | BQD3J33 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $39,376.09 | 6,487 | BK4PZ38 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $38,762.76 | 951 | BL95N25 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,687.92 | 8,952 | BZ0QMB7 |
| 0.04% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $37,684.77 | 16,899 | BF0DMK7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $37,485.00 | 2,205 | BQS7491 |
| 0.04% | GERN | GERON CORP | -- | $35,456.05 | 29,795 | 2370381 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $35,392.95 | 3,645 | BDDVW37 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $35,027.52 | 9,416 | BBNBTD2 |
| 0.04% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $35,023.80 | 5,649 | BYVQJ96 |
| 0.04% | CRMD | CORMEDIX INC | -- | $34,127.94 | 3,486 | BJ0LT31 |
| 0.04% | ATXS | ASTRIA THERAPEUTICS INC | -- | $33,266.32 | 2,636 | BMYRFN8 |
| 0.04% | ALMS | ALUMIS INC | -- | $33,251.40 | 4,524 | BPLQG36 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $32,725.92 | 2,351 | BD06CS0 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $32,573.28 | 1,896 | BM7V485 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $31,280.21 | 14,027 | B4N8MH9 |
| 0.04% | OMER | OMEROS CORP | -- | $30,763.04 | 3,178 | B4NB858 |
| 0.04% | RGNX | REGENXBIO INC | -- | $29,836.80 | 2,368 | BZ0G875 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,648.50 | 2,758 | BM90J52 |
| 0.04% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $29,614.80 | 3,480 | BYP80F1 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,454.88 | 3,757 | BFYQFJ2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,581.00 | 8,166 | BPBJFM7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,547.50 | 7,585 | B3MZ6K5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $25,818.78 | 2,514 | B91XRN2 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,798.05 | 2,659 | BMFK3H6 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $23,080.56 | 16,971 | BWFZX59 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,922.31 | 2,181 | BKLXFX5 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,838.66 | 6,757 | BMCWKZ2 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $22,496.24 | 2,522 | BQ6C357 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $22,442.92 | 4,283 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $21,867.48 | 2,622 | BLFBZ32 |
| 0.03% | ABSI | ABSCI CORP | -- | $21,228.32 | 6,983 | BN94K69 |
| 0.03% | ANNX | ANNEXON INC | -- | $21,170.38 | 5,126 | BMVV9R5 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $20,825.97 | 669 | B292NQ7 |
| 0.02% | HCM | HUTCHMED CHINA-ADR | -- | $20,793.15 | 1,449 | BYXV9H7 |
| 0.02% | EOLS | EVOLUS INC | -- | $20,603.22 | 3,021 | BDRJH21 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $20,321.46 | 4,122 | BFY7DC4 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,845.80 | 898 | BTNMG41 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $19,696.16 | 3,344 | 2107437 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $18,948.77 | 3,637 | BQHN6C7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $18,302.46 | 7,563 | BN4JN37 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,015.21 | 2,901 | BP81R42 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $17,890.78 | 874 | BPBPCG8 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $17,610.07 | 1,777 | BP81RK8 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,923.24 | 5,039 | BDFKQ07 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $15,322.02 | 4,011 | BYTYP72 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $15,178.24 | 2,156 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $14,670.19 | 941 | BN72KB0 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,544.13 | 2,207 | BL5B6Z1 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $14,195.94 | 10,362 | BFZNYB7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,189.35 | 3,997 | BMXNGZ6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,125.86 | 999 | B9L5200 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,850.18 | 2,759 | B12W3P6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,660.16 | 667 | BS2F741 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $13,594.60 | 2,020 | BSMLR16 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,925.08 | 9,366 | BFMLGR4 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,765.66 | 4,659 | BZC0D70 |
| 0.02% | PYXS | PYXIS ONCOLOGY INC | -- | $12,713.44 | 2,896 | BLBR8D5 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $11,645.34 | 2,499 | BP7L561 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,616.00 | 2,640 | BMF7DT9 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,451.54 | 3,706 | BLN9Z50 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,230.50 | 2,590 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $9,970.20 | 5,730 | BN13S71 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,466.88 | 7,396 | BMYTJP4 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,195.81 | 4,199 | BZ8FPH3 |
| 0.01% | PEPG | PEPGEN INC | -- | $8,870.28 | 1,532 | BMTX3D7 |
| 0.01% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,869.50 | 1,215 | BQB9HM8 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,442.96 | 3,324 | BKX9NQ0 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,229.32 | 1,268 | BKC9SX3 |
| 0.01% | MXCT | MAXCYTE INC | -- | $8,115.77 | 4,979 | BKMQF66 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,954.75 | 4,215 | B5LL2C2 |
| 0.01% | MRSN | MERSANA THERAPEUTICS INC | -- | $6,391.19 | 233 | BVPKH99 |
| 0.01% | NKTX | NKARTA INC | -- | $6,003.77 | 3,317 | BK80YJ8 |
| 0.01% | ALEC | ALECTOR INC | -- | $5,814.21 | 4,727 | BJ4LDC4 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $5,665.35 | 3,165 | BMW5LX6 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $5,547.58 | 5,386 | BCZS820 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $4,386.51 | 2,867 | BMDWW66 |
| 0.01% | MGNX | MACROGENICS INC | -- | $4,309.92 | 2,952 | BFDV8K0 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $3,959.27 | 1,141 | BMF1LJ7 |
| -- | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $3,713.90 | 9,186 | BPG5P75 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $3,554.98 | 1,469 | BP2TPK4 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $3,173.14 | 3,959 | BF12XC2 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,806.79 | 2,779 | BNKF6N0 |
| -- | TCRX | TSCAN THERAPEUTICS INC | -- | $2,499.00 | 2,450 | BNLYBJ7 |
| -- | QTTB | Q32 BIO INC | -- | $2,173.58 | 569 | BS2FKQ4 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,704.00 | 600 | BT7KGT6 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $1,622.07 | 6,725 | BJL38Z1 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 37.04% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,089,486 | -- | 5,462 | -- |
| 34.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 29,006,228 | -- | 5,096 | -- |
| 22.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,119,294 | -- | 3,359 | -- |
| 16.85% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,138,829 | -- | 2,484 | -- |
| 15.59% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 13,085,816 | -- | 2,299 | -- |
| 4.29% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,603,011 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,883,189.12 | 25,883,189 | -- |
Index
as of 9/30/2025
- Total Number of Companies251
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.56 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
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