BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,917,396
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/01/2026- NAV
- NAV Change
- Market Price $81.46
- Market Price Change $-3.14
- Trading Volume (M) 5,070
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,917,396
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/01/2026- NAV
- NAV Change
- Market Price $81.46
- Market Price Change $-3.14
- Trading Volume (M) 5,070
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/01/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.73% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,356,828.80 | 7,657 | 2931034 |
| 4.72% | GILD | GILEAD SCIENCES INC | -- | $3,348,556.20 | 25,542 | 2369174 |
| 4.55% | AMGN | AMGEN INC | -- | $3,226,461.39 | 9,803 | 2023607 |
| 3.25% | REGN | REGENERON PHARMACEUTICALS | -- | $2,306,534.40 | 3,840 | 2730190 |
| 2.04% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,449,769.52 | 4,904 | B00FWN1 |
| 1.69% | RVMD | REVOLUTION MEDICINES INC | -- | $1,199,119.68 | 7,326 | BL71K91 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,042,847.75 | 5,425 | 2455965 |
| 1.31% | ILMN | ILLUMINA INC | -- | $929,353.20 | 5,653 | 2613990 |
| 1.24% | UTHR | UNITED THERAPEUTICS CORP | -- | $882,284.40 | 1,620 | 2430412 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $877,894.50 | 1,050 | BDVLM39 |
| 1.23% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $873,885.66 | 15,837 | BMVP7Y0 |
| 1.19% | INSM | INSMED INC | -- | $844,847.04 | 7,968 | 2614487 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $769,721.40 | 26,460 | BMW4NZ9 |
| 0.99% | INCY | INCYTE CORP | -- | $703,446.81 | 7,359 | 2471950 |
| 0.95% | VTRS | VIATRIS INC | -- | $672,952.65 | 42,565 | BMWS3X9 |
| 0.95% | MRNA | MODERNA INC | -- | $672,476.00 | 14,600 | BGSXTS3 |
| 0.88% | GH | GUARDANT HEALTH INC | -- | $626,329.00 | 4,850 | BFXC911 |
| 0.84% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $597,632.00 | 3,712 | 2623911 |
| 0.75% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $529,256.00 | 2,275 | B4Q5ZN4 |
| 0.70% | ASND | ASCENDIS PHARMA A/S | -- | $498,034.32 | 2,276 | BWXJHM8 |
| 0.68% | EXEL | EXELIXIS INC | -- | $482,688.00 | 9,600 | 2576941 |
| 0.67% | MEDP | MEDPACE HOLDINGS INC | -- | $474,494.97 | 1,051 | BDCBC61 |
| 0.66% | BBIO | BRIDGEBIO PHARMA INC | -- | $468,435.12 | 7,167 | BK1KWG8 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $460,496.42 | 6,109 | BDJ0LS6 |
| 0.63% | SMMT | SUMMIT THERAPEUTICS INC | -- | $450,311.44 | 28,664 | BMTVQS7 |
| 0.61% | AXSM | AXSOME THERAPEUTICS INC | -- | $435,172.50 | 1,890 | BYZR4X4 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $407,601.81 | 847 | BD59BS7 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $391,263.30 | 7,110 | 2437071 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $389,385.60 | 5,178 | BYQBFJ8 |
| 0.55% | SNY | SANOFI-ADR | -- | $388,659.12 | 9,047 | 2964557 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $386,332.10 | 4,213 | BK6H543 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $344,879.64 | 1,029 | BQ721R4 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $339,187.20 | 6,424 | BSLSJJ0 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $335,465.04 | 4,553 | BBBSBJ5 |
| 0.47% | ONC | BEONE MEDICINES LTD-ADR | -- | $330,302.08 | 1,181 | BYYWPW6 |
| 0.45% | KRYS | KRYSTAL BIOTECH INC | -- | $321,948.00 | 1,080 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $297,362.96 | 4,364 | 2975098 |
| 0.42% | ABVX | ABIVAX SA-ADR | -- | $294,525.99 | 2,271 | BLC89B2 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $275,177.92 | 38,008 | BNSP0B8 |
| 0.37% | ALKS | ALKERMES PLC | -- | $260,510.01 | 6,163 | B3P6D26 |
| 0.37% | PCVX | VAXCYTE INC | -- | $260,250.11 | 5,321 | BKPVGH6 |
| 0.35% | NUVL | NUVALENT INC-A | -- | $251,592.05 | 2,705 | BMVBZD3 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $247,205.78 | 7,523 | BJRFSB7 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $236,743.99 | 3,017 | BMPRZV5 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $225,975.60 | 3,062 | B17VCN9 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $224,106.12 | 2,361 | BDCBCD8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $221,959.62 | 2,526 | BF2YWG4 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $214,912.23 | 2,231 | BJDX8Y8 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $208,929.62 | 6,002 | BLR6XK8 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $204,918.70 | 2,905 | BQBBDY8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $192,374.50 | 3,550 | BDHF4K6 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $184,975.29 | 3,123 | BRBCSP4 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $178,802.47 | 3,773 | BFZQ0L8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,300.78 | 4,423 | BLB0YQ9 |
| 0.24% | CAI | CARIS LIFE SCIENCES INC | -- | $171,589.95 | 10,431 | BT18HP9 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $169,118.08 | 736 | 2501578 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $164,182.34 | 3,074 | BRJ3GY4 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $161,285.12 | 4,624 | BTZRLN8 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $160,820.40 | 2,028 | BM9HHL5 |
| 0.23% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $159,671.16 | 3,966 | BKY5JZ8 |
| 0.22% | ERAS | ERASCA INC | -- | $158,156.08 | 11,444 | BNLYBF3 |
| 0.22% | TWST | TWIST BIOSCIENCE CORP | -- | $153,770.76 | 2,266 | BGKG6G7 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $153,541.36 | 3,409 | BLFGJD5 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $150,052.80 | 11,632 | BFNF1D6 |
| 0.20% | VCYT | VERACYTE INC | -- | $141,552.84 | 2,938 | BFTWZY0 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $135,640.56 | 6,303 | 2713317 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $135,171.08 | 4,252 | BP8JSP4 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $133,661.44 | 3,872 | BDD19F8 |
| 0.18% | TXG | 10X GENOMICS INC-CLASS A | -- | $128,746.09 | 4,351 | BKS3RS7 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $119,663.83 | 5,863 | BD2B4V0 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $117,304.38 | 3,767 | BK6L288 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $114,991.80 | 4,978 | BP2P6L0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $113,400.81 | 6,087 | BN15WD1 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $111,024.00 | 2,880 | BQS9486 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $101,549.67 | 1,411 | BMGJZJ8 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $98,482.89 | 4,587 | BKX9VD3 |
| 0.14% | ORKA | ORUKA THERAPEUTICS INC | -- | $98,412.89 | 1,789 | BKVF0J2 |
| 0.13% | ALMS | ALUMIS INC | -- | $95,022.42 | 4,674 | BPLQG36 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $94,891.20 | 2,120 | B72ZBG4 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $94,201.56 | 6,606 | BN2R582 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $93,939.24 | 3,246 | BK0VHF6 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $92,696.89 | 1,573 | BMH5RL1 |
| 0.13% | GRAL | GRAIL INC | -- | $92,671.60 | 1,439 | BSLSSX7 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $90,996.75 | 2,925 | BP9N0G0 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $89,465.84 | 2,636 | BL55460 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $88,661.10 | 3,685 | BV2DHY6 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $86,689.16 | 5,692 | BJ5FZ74 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $83,232.05 | 2,255 | BFXC933 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $82,371.96 | 2,196 | BMFD115 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $82,234.14 | 1,698 | BRXB0C0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $81,597.35 | 3,571 | BJ62Z18 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $79,642.22 | 3,122 | BMX9K07 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $79,452.47 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $75,233.34 | 4,914 | BFWLC09 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $73,135.63 | 19,297 | BM9FJ13 |
| 0.10% | ABCL | ABCELLERA BIOLOGICS INC | -- | $72,410.14 | 11,209 | BL53SR3 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,877.57 | 8,049 | BNZB1X8 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $69,701.04 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $69,559.50 | 8,805 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $68,879.70 | 2,367 | BMZ2X38 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $68,238.75 | 3,875 | B8DPDT7 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,073.40 | 2,140 | BKSGZN7 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $67,877.64 | 2,766 | BPCQZY9 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $67,525.90 | 1,651 | BQKXDX4 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $66,150.90 | 4,742 | BJH9ZN0 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $66,116.78 | 3,802 | BMVLGP2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,462.04 | 1,764 | BR3T9B6 |
| 0.09% | QURE | UNIQURE NV | -- | $65,047.10 | 2,305 | BJFSR88 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $64,727.78 | 13,429 | BWJDYK1 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $64,322.17 | 2,111 | BJQ05Z6 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $63,669.30 | 830 | BCDWBX6 |
| 0.09% | NVAX | NOVAVAX INC | -- | $63,301.73 | 6,023 | BJDQXG4 |
| 0.09% | VCEL | VERICEL CORP | -- | $61,537.50 | 1,875 | BSBMN89 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $61,469.85 | 3,261 | BN7Q7R7 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $60,648.00 | 2,166 | BCBVTX1 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $60,545.55 | 2,379 | BBC9WC7 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $60,464.16 | 10,128 | BNC1BX1 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,318.72 | 15,232 | BF0DMK7 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $59,989.86 | 1,974 | BMVNDH9 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $59,986.37 | 4,369 | BYZM6C2 |
| 0.08% | INVA | INNOVIVA INC | -- | $58,937.40 | 2,740 | BDDXF67 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $57,110.13 | 4,059 | BPCK358 |
| 0.08% | GHRS | GH RESEARCH PLC | -- | $56,960.02 | 2,294 | BP6C0S2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $55,430.06 | 2,818 | BP7KZP7 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $54,450.80 | 3,455 | BRXYZ57 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $54,362.22 | 1,023 | BDRW1L7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $53,889.60 | 13,080 | BKM5C84 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $53,318.73 | 537 | BNSP8K3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $52,464.30 | 5,810 | BK4PZ38 |
| 0.07% | ARDX | ARDELYX INC | -- | $51,948.18 | 9,066 | BN89V40 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $50,817.70 | 1,658 | BQXJKH2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,377.80 | 1,870 | BD06CS0 |
| 0.07% | SEPN | SEPTERNA INC | -- | $49,676.86 | 1,657 | BQNKXX2 |
| 0.07% | CMPS | COMPASS PATHWAYS PLC | -- | $49,480.53 | 3,487 | BMC3HS7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $48,312.66 | 2,343 | BQB42F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $47,219.73 | 1,621 | BLCD809 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,848.36 | 1,527 | BMGTLY5 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $46,761.90 | 1,730 | BZ7PJQ1 |
| 0.07% | HROW | HARROW INC | -- | $46,730.70 | 1,370 | BHNDW86 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $45,267.88 | 1,778 | BSRK699 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $43,569.60 | 6,960 | BYZG9R0 |
| 0.06% | PSNL | PERSONALIS INC | -- | $43,564.94 | 3,869 | BJQ0608 |
| 0.06% | EYPT | EYEPOINT INC | -- | $40,265.30 | 3,062 | BMGS7L1 |
| 0.06% | MNKD | MANNKIND CORP | -- | $40,203.17 | 11,389 | BF081J4 |
| 0.06% | ALVO | ALVOTECH SA | -- | $39,316.20 | 12,210 | BPNTJ34 |
| 0.05% | SVRA | SAVARA INC | -- | $38,748.60 | 7,524 | BYXGN81 |
| 0.05% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $37,647.02 | 2,962 | BMZ4LN0 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $37,246.16 | 1,172 | BX7RSN3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $37,233.38 | 6,134 | BLR7H87 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $36,892.32 | 3,054 | BYP80F1 |
| 0.05% | ABSI | ABSCI CORP | -- | $36,257.72 | 5,561 | BN94K69 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,031.11 | 1,983 | BQB42H3 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,418.85 | 2,185 | BM90J52 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,907.40 | 4,510 | B8K7T65 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,476.08 | 3,656 | BMCR7V2 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,325.20 | 1,495 | B3X26D8 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $33,324.78 | 3,711 | BKVDFF7 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $32,436.91 | 2,251 | BMFX8Y7 |
| 0.05% | XNCR | XENCOR INC | -- | $31,989.80 | 2,711 | BGCYWN8 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,852.80 | 7,110 | BZ0QMB7 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,615.29 | 9,849 | BMFJJ97 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,890.34 | 1,677 | BNFWZS4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $29,887.50 | 1,875 | BMNDK09 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,847.42 | 5,349 | BMVV9R5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,155.00 | 2,975 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $29,074.63 | 3,218 | BYZD465 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,739.24 | 1,934 | BQS7491 |
| 0.04% | GERN | GERON CORP | -- | $28,558.42 | 23,602 | 2370381 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $28,450.56 | 992 | BGL0JK3 |
| 0.04% | OMER | OMEROS CORP | -- | $28,107.84 | 2,622 | B4NB858 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $27,588.80 | 1,604 | BT9K6D8 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $27,477.00 | 3,053 | BDDVW37 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $26,906.88 | 2,912 | BJLKVS6 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $25,697.50 | 5,410 | BMCWKZ2 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,597.95 | 2,911 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,933.67 | 2,083 | BLFBZ32 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,067.00 | 1,100 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,036.57 | 2,707 | BP0TQC5 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $22,790.81 | 763 | BL95N25 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $22,688.20 | 6,673 | BPBJFM7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $22,379.52 | 1,536 | BRJJYT3 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $21,976.20 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,687.21 | 1,269 | BD9GVY0 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $21,614.25 | 6,265 | BYWVTY5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $20,856.88 | 6,028 | B3MZ6K5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,707.20 | 2,880 | BQHN6C7 |
| 0.03% | ARVN | ARVINAS INC | -- | $20,274.54 | 2,363 | BDZ30Q0 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,065.92 | 672 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,020.77 | 693 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,352.06 | 4,459 | BYV2W40 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $19,074.51 | 1,989 | B91XRN2 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $18,506.07 | 1,023 | BS2CR64 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,303.35 | 1,885 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,044.00 | 4,511 | BYVQJ96 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,862.20 | 8,308 | BFZNYB7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,637.54 | 11,163 | B4N8MH9 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,360.64 | 2,112 | BSMLR16 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,889.31 | 2,349 | BP81R42 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,431.80 | 2,134 | B2Q9833 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,135.76 | 1,997 | BRCFFK6 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $15,818.88 | 2,464 | BJDX8Z9 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,807.42 | 3,609 | BKX9NQ0 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,725.34 | 571 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,628.44 | 2,397 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,091.92 | 548 | B292NQ7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,713.16 | 1,124 | BPRBTY7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,089.14 | 4,014 | BMXNGZ6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,939.31 | 4,631 | BFY7DC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,913.89 | 2,186 | B12W3P6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,890.42 | 5,322 | BN13S71 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,641.76 | 7,414 | BFMLGR4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,582.24 | 1,072 | B9L5200 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,497.05 | 787 | BTNMG41 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,378.48 | 1,879 | B7F2TY6 |
| 0.02% | RGNX | REGENXBIO INC | -- | $13,373.22 | 1,873 | BZ0G875 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,054.19 | 3,557 | BK5MWR1 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,972.57 | 2,697 | BQ6C357 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,653.82 | 2,889 | BLN9Z50 |
| 0.02% | IVVD | INVIVYD INC | -- | $12,497.68 | 10,244 | BM8NHS1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,262.50 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,119.26 | 4,013 | BDFKQ07 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,060.74 | 3,611 | BZ8FPH3 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,748.24 | 2,646 | 2107437 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,336.08 | 1,736 | BL5B6Z1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,240.32 | 6,176 | BN4JN37 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,729.57 | 2,387 | BMVBZF5 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $10,637.97 | 1,981 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,347.20 | 7,136 | BMYTJP4 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $10,209.48 | 3,426 | BYTYP72 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,784.56 | 1,416 | BP81RK8 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,153.66 | 3,721 | BZC0D70 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,920.47 | 3,341 | B5LL2C2 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,674.25 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,615.52 | 1,158 | BQV0J03 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,605.88 | 2,165 | BMF7DT9 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,531.40 | 7,230 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,393.22 | 3,454 | BNYJR68 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,258.41 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,246.93 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,174.04 | 1,052 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,000.87 | 2,089 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,750.83 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,098.21 | 4,151 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,970.44 | 8,012 | BNNXX52 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,726.95 | 1,387 | 2517058 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,650.58 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,757.30 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,122.37 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,735.27 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,231.69 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,207.96 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,694.75 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 30.61% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 21,703,865 | -- | 3,692 | -- |
| 29.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,716,257 | -- | 3,524 | -- |
| 27.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,834,464 | -- | 3,374 | -- |
| 21.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,513,678 | -- | 2,639 | -- |
| 20.83% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,772,972 | -- | 2,513 | -- |
| 5.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,721,166 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,007,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $20,341,760.93 | 20,341,761 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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