BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/10/2026- NAV $85.11
- NAV Change $+1.23
- Market Price $85.03
- Market Price Change $+1.12
- Trading Volume (M) 12,071
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/10/2026- NAV $85.11
- NAV Change $+1.23
- Market Price $85.03
- Market Price Change $+1.12
- Trading Volume (M) 12,071
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/09/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.65% | GILD | GILEAD SCIENCES INC | -- | $5,688,950.74 | 38,798 | 2369174 |
| 6.23% | AMGN | AMGEN INC | -- | $5,328,093.98 | 14,134 | 2023607 |
| 6.06% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,188,935.33 | 11,259 | 2931034 |
| 4.24% | REGN | REGENERON PHARMACEUTICALS | -- | $3,624,279.20 | 4,637 | 2730190 |
| 2.24% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,919,212.29 | 5,931 | B00FWN1 |
| 1.60% | INSM | INSMED INC | -- | $1,370,326.62 | 9,574 | 2614487 |
| 1.45% | BIIB | BIOGEN INC | -- | $1,239,748.64 | 6,586 | 2455965 |
| 1.19% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,022,356.44 | 1,932 | 2430412 |
| 1.14% | MRNA | MODERNA INC | -- | $977,623.86 | 17,539 | BGSXTS3 |
| 1.13% | ARGX | ARGENX SE - ADR | -- | $966,962.40 | 1,306 | BDVLM39 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $922,044.72 | 31,224 | BMW4NZ9 |
| 1.03% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $879,348.72 | 19,183 | BMVP7Y0 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $866,077.41 | 8,679 | BL71K91 |
| 1.00% | INCY | INCYTE CORP | -- | $855,742.30 | 8,813 | 2471950 |
| 1.00% | ILMN | ILLUMINA INC | -- | $852,436.52 | 6,859 | 2613990 |
| 0.86% | VTRS | VIATRIS INC | -- | $735,301.98 | 51,709 | BMWS3X9 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $661,459.44 | 2,757 | BV9G6B8 |
| 0.71% | MEDP | MEDPACE HOLDINGS INC | -- | $605,353.10 | 1,265 | BDCBC61 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $581,566.68 | 4,476 | 2623911 |
| 0.66% | BBIO | BRIDGEBIO PHARMA INC | -- | $567,851.64 | 8,651 | BK1KWG8 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $547,942.56 | 7,271 | BDJ0LS6 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $529,689.60 | 5,808 | BFXC911 |
| 0.62% | SNY | SANOFI-ADR | -- | $526,922.35 | 11,881 | 2964557 |
| 0.61% | SMMT | SUMMIT THERAPEUTICS INC | -- | $525,409.56 | 33,423 | BMTVQS7 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $525,090.00 | 8,625 | 2437071 |
| 0.60% | EXEL | EXELIXIS INC | -- | $510,007.69 | 12,037 | 2576941 |
| 0.59% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $505,771.20 | 2,728 | B4Q5ZN4 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $463,704.24 | 4,539 | BK6H543 |
| 0.52% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $440,997.60 | 1,018 | BD59BS7 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $427,438.06 | 1,414 | BYYWPW6 |
| 0.47% | TEM | ADD | -- | $406,003.20 | 7,760 | BSLSJJ0 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $373,667.45 | 44,221 | BNSP0B8 |
| 0.44% | AXSM | AXSOME THERAPEUTICS INC | -- | $372,240.87 | 2,263 | BYZR4X4 |
| 0.43% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $369,904.99 | 6,097 | BYQBFJ8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $359,779.20 | 5,280 | 2975098 |
| 0.41% | PCVX | VAXCYTE INC | -- | $348,564.32 | 5,876 | BKPVGH6 |
| 0.41% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $347,018.23 | 1,123 | BQ721R4 |
| 0.40% | CYTK | CYTOKINETICS INC | -- | $342,685.80 | 5,490 | BBBSBJ5 |
| 0.39% | KRYS | KRYSTAL BIOTECH INC | -- | $336,503.65 | 1,301 | BD6JX35 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $331,823.76 | 3,243 | BMVBZD3 |
| 0.35% | ACLX | ARCELLX INC | -- | $297,242.00 | 2,596 | BPCJ1Q2 |
| 0.34% | ABVX | ABIVAX SA-ADR | -- | $290,466.50 | 2,650 | BLC89B2 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $278,628.00 | 2,996 | BF2YWG4 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $274,679.20 | 3,230 | BMPRZV5 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $271,324.62 | 2,807 | BDCBCD8 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $255,072.92 | 6,892 | BLR6XK8 |
| 0.29% | CRSP | CRISPR THERAPEUTICS AG | -- | $251,460.84 | 4,278 | BDHF4K6 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $246,582.00 | 3,605 | B17VCN9 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $240,673.00 | 12,667 | BT18HP9 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $221,931.09 | 3,621 | BRBCSP4 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $217,777.20 | 3,470 | BRJ3GY4 |
| 0.25% | ALKS | ALKERMES PLC | -- | $210,871.40 | 7,412 | B3P6D26 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $207,846.70 | 7,870 | BJRFSB7 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $204,815.46 | 2,307 | BJDX8Y8 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $202,573.40 | 4,580 | BFZQ0L8 |
| 0.23% | ERAS | ERASCA INC | -- | $200,735.12 | 12,737 | BNLYBF3 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $199,067.61 | 13,853 | B19FQ48 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $187,010.50 | 14,114 | BFNF1D6 |
| 0.22% | APGE | APOGEE THERAPEUTICS INC | -- | $184,502.28 | 2,462 | BM9HHL5 |
| 0.21% | LGND | LIGAND PHARMACEUTICALS | -- | $183,805.28 | 883 | 2501578 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $182,657.80 | 5,603 | BTZRLN8 |
| 0.21% | TERN | TERNS PHARMACEUTICALS INC | -- | $179,108.76 | 4,044 | BMDJ0C9 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $171,517.68 | 7,596 | 2713317 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $169,500.00 | 3,000 | BQS9486 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $168,945.66 | 10,686 | B9NSBM2 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $162,817.20 | 4,260 | BDD19F8 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $156,619.30 | 5,090 | BP8JSP4 |
| 0.17% | SYRE | SPYRE THERAPEUTICS INC | -- | $143,046.81 | 3,483 | BQBBDY8 |
| 0.17% | TARS | TARSUS PHARMACEUTICALS INC | -- | $142,052.43 | 1,907 | BMH5RL1 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $140,305.04 | 6,584 | BD2B4V0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $139,433.58 | 2,574 | B72ZBG4 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $138,074.88 | 3,936 | BK0VHF6 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $136,510.00 | 5,500 | BKX9VD3 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $136,220.98 | 4,753 | BKY5JZ8 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $132,665.85 | 2,745 | BGKG6G7 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $125,809.10 | 4,555 | BK6L288 |
| 0.14% | VCYT | VERACYTE INC | -- | $118,396.76 | 3,548 | BFTWZY0 |
| 0.14% | ALMS | ALUMIS INC | -- | $117,156.60 | 4,365 | BPLQG36 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $116,412.66 | 4,017 | BLFGJD5 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $113,483.23 | 5,677 | BYTQ6X1 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $113,445.97 | 6,413 | BN15WD1 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $112,995.79 | 4,331 | BLB0YQ9 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $111,765.96 | 2,868 | BL55460 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $109,338.39 | 5,229 | BKS3RS7 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $108,934.08 | 1,696 | BMGJZJ8 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $102,452.35 | 6,853 | BJ5FZ74 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $99,794.61 | 7,509 | BYZG9R0 |
| 0.12% | TNGX | TANGO THERAPEUTICS INC | -- | $99,473.15 | 6,047 | BP2P6L0 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $98,309.97 | 4,609 | BLB0YH0 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $98,226.84 | 2,564 | BJQ05Z6 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,923.91 | 4,331 | BJ62Z18 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $97,329.60 | 2,160 | BSRK699 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $96,756.48 | 3,552 | BP9N0G0 |
| 0.11% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $96,417.02 | 17,822 | BF0DMK7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $95,076.10 | 9,565 | BNZB1X8 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,788.72 | 2,028 | BRXB0C0 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $93,179.76 | 3,902 | BN7Q7R7 |
| 0.10% | GRAL | GRAIL INC | -- | $87,185.00 | 1,750 | BSLSSX7 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $85,070.40 | 5,920 | BFWLC09 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $82,978.56 | 4,704 | B8DPDT7 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $81,480.00 | 3,360 | BPCQZY9 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $81,476.24 | 9,452 | 2100362 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $81,143.70 | 4,422 | BV2DHY6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $81,028.35 | 23,085 | BM9FJ13 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $80,865.00 | 2,396 | BMVNDH9 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $79,230.45 | 2,665 | BMFD115 |
| 0.09% | RLAY | RELAY THERAPEUTICS INC | -- | $78,899.34 | 7,781 | BN2R582 |
| 0.09% | VCEL | VERICEL CORP | -- | $77,486.52 | 2,271 | BSBMN89 |
| 0.09% | NVAX | NOVAVAX INC | -- | $76,972.80 | 7,296 | BJDQXG4 |
| 0.09% | PHVS | PHARVARIS NV | -- | $76,242.76 | 2,876 | BMZ2X38 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,483.29 | 1,009 | BCDWBX6 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $75,172.59 | 2,003 | BQKXDX4 |
| 0.09% | INVA | INNOVIVA INC | -- | $74,928.24 | 3,357 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,691.54 | 2,618 | BCBVTX1 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $74,147.40 | 1,242 | BDRW1L7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,882.02 | 2,586 | BKSGZN7 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,155.10 | 2,174 | BKVF0J2 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,349.20 | 3,780 | BMX9K07 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $72,228.00 | 5,200 | BYZM6C2 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $71,505.00 | 2,625 | BBC9WC7 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $70,562.61 | 4,931 | BPCK358 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $70,525.00 | 4,550 | BMVLGP2 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $67,356.90 | 5,757 | BJH9ZN0 |
| 0.08% | ARDX | ARDELYX INC | -- | $67,302.36 | 10,908 | BN89V40 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $65,450.19 | 1,959 | BLCD809 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,325.06 | 2,139 | BR3T9B6 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $64,898.57 | 5,027 | BYSS4X4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $63,430.34 | 16,306 | BWJDYK1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $62,997.40 | 2,410 | BQB42H3 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $61,265.04 | 2,382 | BFXC933 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $61,210.80 | 6,246 | BK4PZ38 |
| 0.07% | HROW | HARROW INC | -- | $58,419.30 | 1,662 | BHNDW86 |
| 0.07% | SEPN | SEPTERNA INC | -- | $58,381.54 | 2,009 | BQNKXX2 |
| 0.07% | EYPT | EYEPOINT INC | -- | $58,229.72 | 3,716 | BMGS7L1 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,512.00 | 3,532 | BMZ4LN0 |
| 0.07% | ALVO | ALVOTECH SA | -- | $56,497.08 | 14,054 | BPNTJ34 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,447.82 | 12,298 | BNC1BX1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $56,299.10 | 2,015 | BQXJKH2 |
| 0.07% | PGEN | PRECIGEN INC | -- | $55,759.86 | 15,886 | BKM5C84 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,279.17 | 3,353 | BYP80F1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $52,923.40 | 1,420 | BX7RSN3 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $51,620.18 | 2,923 | BP7KZP7 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $50,945.45 | 4,373 | BKVDFF7 |
| 0.06% | QURE | UNIQURE NV | -- | $50,318.03 | 2,797 | BJFSR88 |
| 0.06% | SVRA | SAVARA INC | -- | $49,603.05 | 9,135 | BYXGN81 |
| 0.06% | BCAX | BICARA THERAPEUTICS INC | -- | $48,462.00 | 2,460 | BQB42F1 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $47,978.52 | 5,477 | B8K7T65 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,301.76 | 13,438 | BL53SR3 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $46,996.44 | 654 | BNSP8K3 |
| 0.05% | GERN | GERON CORP | -- | $46,425.96 | 28,658 | 2370381 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,997.74 | 1,854 | BMGTLY5 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $44,877.60 | 920 | BL95N25 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $44,488.32 | 2,784 | BP6C0S2 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,923.20 | 1,930 | B3X26D8 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $41,850.82 | 2,102 | BZ7PJQ1 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,720.00 | 7,450 | BLR7H87 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,774.84 | 4,148 | BRXYZ57 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $40,757.20 | 8,635 | BZ0QMB7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $40,602.12 | 2,652 | BM90J52 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $40,163.90 | 4,438 | BMCR7V2 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,826.80 | 11,960 | BMFJJ97 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,649.44 | 2,064 | BNFWZS4 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,271.00 | 2,270 | BD06CS0 |
| 0.05% | ARVN | ARVINAS INC | -- | $38,545.71 | 2,883 | BDZ30Q0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $38,263.21 | 7,607 | BYWVTY5 |
| 0.04% | XNCR | XENCOR INC | -- | $38,055.22 | 3,206 | BGCYWN8 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $37,759.98 | 2,701 | BMFX8Y7 |
| 0.04% | MNKD | MANNKIND CORP | -- | $36,946.48 | 13,786 | BF081J4 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $36,677.34 | 3,906 | BYZD465 |
| 0.04% | ANNX | ANNEXON INC | -- | $36,318.23 | 6,497 | BMVV9R5 |
| 0.04% | OMER | OMEROS CORP | -- | $35,947.36 | 3,184 | B4NB858 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $35,474.23 | 3,193 | BJLKVS6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $35,396.20 | 1,310 | BKLCWZ3 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,976.86 | 2,202 | BQS7491 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $33,612.96 | 1,758 | BD9GVY0 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $33,303.33 | 8,103 | BPBJFM7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $32,625.28 | 10,732 | BBNBTD2 |
| 0.04% | PSNL | PERSONALIS INC | -- | $32,533.92 | 3,987 | BJQ0608 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,864.00 | 2,276 | BMNDK09 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,765.30 | 1,610 | BT9K6D8 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $30,394.86 | 3,522 | BDDVW37 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $29,024.66 | 4,231 | BMC3HS7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $28,560.00 | 840 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $28,053.96 | 3,498 | BQHN6C7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,659.60 | 7,304 | B3MZ6K5 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $26,627.81 | 3,613 | BFYQFJ2 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,526.46 | 2,558 | BMFK3H6 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $25,222.50 | 10,089 | BFZNYB7 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $24,793.72 | 4,852 | BDFKQ07 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $24,373.44 | 3,276 | BQ6C357 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $24,250.50 | 951 | BTNMG41 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $24,153.22 | 7,501 | BN4JN37 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,710.77 | 2,417 | B91XRN2 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,631.30 | 6,510 | BMCWKZ2 |
| 0.03% | RGNX | REGENXBIO INC | -- | $23,593.74 | 2,273 | BZ0G875 |
| 0.03% | IVVD | INVIVYD INC | -- | $23,515.38 | 12,442 | BM8NHS1 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $23,496.33 | 5,477 | BYVQJ96 |
| 0.03% | KMDA | KAMADA LTD | -- | $23,258.20 | 2,590 | B2Q9833 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,209.28 | 3,538 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,055.36 | 2,528 | BLFBZ32 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $23,028.04 | 2,653 | B12W3P6 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,848.98 | 814 | BQD3J33 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,383.72 | 2,564 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $21,866.67 | 3,843 | BMXNGZ6 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,805.90 | 1,717 | BP81RK8 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $21,568.05 | 3,507 | BLN9Z50 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $21,489.00 | 650 | B292NQ7 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $20,123.50 | 1,205 | BGL0JK3 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $19,545.50 | 2,425 | BRCFFK6 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,286.26 | 2,429 | BJDX8Z9 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $19,212.69 | 4,011 | BYTYP72 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,841.45 | 13,555 | B4N8MH9 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,177.80 | 4,685 | BFY7DC4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $18,004.00 | 3,215 | 2107437 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,001.44 | 1,296 | B9L5200 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $17,281.50 | 1,405 | BQV0J03 |
| 0.02% | PEPG | PEPGEN INC | -- | $17,194.59 | 3,087 | BMTX3D7 |
| 0.02% | ABSI | ABSCI CORP | -- | $16,947.52 | 6,752 | BN94K69 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,522.80 | 1,967 | BSMLR16 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,492.35 | 4,865 | BYV2W40 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,402.00 | 695 | BS2F741 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $16,357.84 | 4,667 | BKRRKY7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $16,292.38 | 2,899 | BMVBZF5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,159.50 | 2,850 | BP81R42 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,620.09 | 4,351 | BKX9NQ0 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,573.85 | 2,911 | BDRJH21 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,526.80 | 1,368 | BM7V485 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $14,589.72 | 9,006 | BFMLGR4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,129.67 | 4,321 | BK5MWR1 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,069.64 | 2,262 | B7F2TY6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,040.98 | 1,037 | BPRBTY7 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,913.72 | 2,539 | BMF7DT9 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,054.71 | 2,109 | BL5B6Z1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,892.88 | 4,508 | BZC0D70 |
| 0.01% | CADL | CANDEL THERAPEUTICS INC | -- | $12,645.45 | 2,465 | BP0TQC5 |
| 0.01% | OABI | OMNIAB INC | -- | $12,602.85 | 6,463 | BN13S71 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,838.45 | 2,535 | BPRB2N7 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $11,740.36 | 1,682 | 2517058 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $11,687.76 | 756 | BRJJYT3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,168.88 | 2,076 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,870.95 | 2,645 | BY7RB53 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,474.11 | 5,427 | BRK0149 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,170.88 | 4,384 | BZ8FPH3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,088.40 | 8,407 | BMYTJP4 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,391.36 | 1,276 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,266.12 | 4,196 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,129.40 | 8,780 | BNR5QT9 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,020.55 | 3,413 | BPTK6Z2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,488.96 | 1,392 | BP2NYN2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,157.10 | 7,474 | BNNXX52 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,044.40 | 4,380 | BNNXX18 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,949.93 | 977 | BTXQTX3 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $5,770.12 | 10,391 | BJ0CK86 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,578.62 | 2,559 | BKTV702 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,094.36 | 2,403 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,068.75 | 4,055 | B5LL2C2 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $4,192.50 | 2,795 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $24.98 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 35.61% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,466,708 | -- | 5,163 | -- |
| 29.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,321,062 | -- | 4,291 | -- |
| 26.39% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,577,111 | -- | 3,826 | -- |
| 18.20% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,572,660 | -- | 2,639 | -- |
| 17.13% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,658,009 | -- | 2,484 | -- |
| 4.37% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,735,314 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,912,483.80 | 26,912,484 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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