BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,506,188
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/12/2026- NAV
- NAV Change
- Market Price $85.10
- Market Price Change $+1.90
- Trading Volume (M) 5,041
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,506,188
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/12/2026- NAV
- NAV Change
- Market Price $85.10
- Market Price Change $+1.90
- Trading Volume (M) 5,041
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/12/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.74% | GILD | GILEAD SCIENCES INC | -- | $3,670,772.82 | 27,203 | 2369174 |
| 4.72% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,654,908.37 | 8,153 | 2931034 |
| 4.53% | AMGN | AMGEN INC | -- | $3,510,531.31 | 10,439 | 2023607 |
| 3.82% | REGN | REGENERON PHARMACEUTICALS | -- | $2,958,023.49 | 4,089 | 2730190 |
| 1.97% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,524,396.60 | 5,220 | B00FWN1 |
| 1.49% | BIIB | BIOGEN INC | -- | $1,151,304.00 | 5,775 | 2455965 |
| 1.47% | RVMD | REVOLUTION MEDICINES INC | -- | $1,136,761.72 | 7,801 | BL71K91 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,003,501.50 | 1,725 | 2430412 |
| 1.27% | INSM | INSMED INC | -- | $984,492.00 | 8,487 | 2614487 |
| 1.17% | ARGX | ARGENX SE - ADR | -- | $907,908.77 | 1,117 | BDVLM39 |
| 1.13% | ILMN | ILLUMINA INC | -- | $877,114.00 | 6,020 | 2613990 |
| 1.12% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $871,972.20 | 16,866 | BMVP7Y0 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $828,268.98 | 28,182 | BMW4NZ9 |
| 1.07% | MRNA | MODERNA INC | -- | $828,188.69 | 15,547 | BGSXTS3 |
| 1.00% | VTRS | VIATRIS INC | -- | $778,367.61 | 45,333 | BMWS3X9 |
| 1.00% | INCY | INCYTE CORP | -- | $776,980.94 | 7,838 | 2471950 |
| 0.79% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $615,721.60 | 3,952 | 2623911 |
| 0.75% | SMMT | SUMMIT THERAPEUTICS INC | -- | $578,505.60 | 30,528 | BMTVQS7 |
| 0.74% | ASND | ASCENDIS PHARMA A/S | -- | $575,825.95 | 2,423 | BWXJHM8 |
| 0.71% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $552,056.32 | 2,423 | B4Q5ZN4 |
| 0.67% | GH | GUARDANT HEALTH INC | -- | $515,990.22 | 5,163 | BFXC911 |
| 0.65% | EXEL | EXELIXIS INC | -- | $505,728.50 | 10,225 | 2576941 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $503,396.35 | 7,633 | BK1KWG8 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $493,274.15 | 6,505 | BDJ0LS6 |
| 0.60% | MEDP | MEDPACE HOLDINGS INC | -- | $468,860.75 | 1,117 | BDCBC61 |
| 0.60% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $461,275.04 | 904 | BD59BS7 |
| 0.58% | AXSM | AXSOME THERAPEUTICS INC | -- | $451,196.42 | 2,014 | BYZR4X4 |
| 0.56% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $435,984.64 | 5,516 | BYQBFJ8 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $420,065.10 | 4,485 | BK6H543 |
| 0.53% | SNY | SANOFI-ADR | -- | $412,913.24 | 9,634 | 2964557 |
| 0.52% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $400,407.36 | 7,572 | 2437071 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $396,673.13 | 1,259 | BYYWPW6 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $376,147.20 | 1,096 | BQ721R4 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $362,828.50 | 4,850 | BBBSBJ5 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $358,097.74 | 1,154 | BD6JX35 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $329,682.64 | 4,648 | 2975098 |
| 0.42% | IBRX | IMMUNITYBIO INC | -- | $328,705.72 | 40,481 | BNSP0B8 |
| 0.41% | TEM | TEMPUS AI INC-CL A | -- | $321,044.10 | 6,838 | BSLSJJ0 |
| 0.39% | PCVX | VAXCYTE INC | -- | $306,079.95 | 5,665 | BKPVGH6 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $295,520.28 | 2,882 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $293,399.63 | 2,417 | BLC89B2 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $268,446.15 | 3,213 | BMPRZV5 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $253,946.88 | 2,376 | BJDX8Y8 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $251,274.30 | 2,514 | BDCBCD8 |
| 0.32% | ALKS | ALKERMES PLC | -- | $251,258.98 | 6,562 | B3P6D26 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $245,623.90 | 2,690 | BF2YWG4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $244,415.16 | 3,258 | B17VCN9 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $239,632.75 | 3,325 | BRBCSP4 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $232,023.68 | 3,092 | BQBBDY8 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $229,687.05 | 8,017 | BJRFSB7 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $220,715.76 | 6,392 | BLR6XK8 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $206,654.98 | 5,033 | BYTQ6X1 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $199,644.57 | 3,779 | BDHF4K6 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $197,645.42 | 4,018 | BFZQ0L8 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $188,414.16 | 4,922 | BTZRLN8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $186,523.49 | 4,709 | BLB0YQ9 |
| 0.24% | CAI | CARIS LIFE SCIENCES INC | -- | $186,203.60 | 11,110 | BT18HP9 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $180,180.00 | 3,276 | BRJ3GY4 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $179,045.87 | 2,159 | BM9HHL5 |
| 0.23% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $176,016.14 | 4,526 | BP8JSP4 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $174,048.00 | 784 | 2501578 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $156,088.80 | 12,388 | BFNF1D6 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $155,637.72 | 3,633 | BLFGJD5 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $152,143.02 | 4,122 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $145,762.92 | 6,711 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $143,658.24 | 4,224 | BKY5JZ8 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $135,063.30 | 2,414 | BGKG6G7 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $126,667.38 | 4,011 | BK6L288 |
| 0.16% | ERAS | ERASCA INC | -- | $126,542.58 | 12,191 | BNLYBF3 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $124,597.00 | 5,302 | BP2P6L0 |
| 0.16% | VCYT | VERACYTE INC | -- | $123,862.36 | 3,131 | BFTWZY0 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $123,222.90 | 1,906 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $121,508.24 | 6,244 | BD2B4V0 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $119,074.34 | 6,482 | BN15WD1 |
| 0.15% | ALMS | ALUMIS INC | -- | $117,032.78 | 4,978 | BPLQG36 |
| 0.15% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $116,130.96 | 3,069 | BQS9486 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $114,096.74 | 2,258 | B72ZBG4 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $107,539.84 | 1,808 | BRXB0C0 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $103,127.00 | 2,810 | BL55460 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $103,069.12 | 1,504 | BMGJZJ8 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,126.20 | 3,805 | BJ62Z18 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $100,967.20 | 4,880 | BKX9VD3 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $100,275.08 | 1,676 | BMH5RL1 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $98,939.70 | 2,339 | BMFD115 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $97,267.08 | 3,459 | BK0VHF6 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $96,901.44 | 4,632 | BKS3RS7 |
| 0.12% | GRAL | GRAIL INC | -- | $94,953.36 | 1,532 | BSLSSX7 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $94,854.98 | 2,402 | BFXC933 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $93,907.98 | 3,323 | BMX9K07 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $91,174.16 | 3,116 | BP9N0G0 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $90,988.41 | 7,037 | BN2R582 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $86,908.80 | 9,876 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $83,723.64 | 5,236 | BFWLC09 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $83,074.16 | 3,926 | BV2DHY6 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $82,638.69 | 6,063 | BJ5FZ74 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $82,028.80 | 4,480 | BYSS4X4 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $78,930.38 | 4,126 | B8DPDT7 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $78,877.39 | 9,379 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,812.50 | 2,522 | BMZ2X38 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $78,510.36 | 8,571 | BNZB1X8 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $74,508.48 | 5,048 | BJH9ZN0 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $73,870.40 | 10,784 | BNC1BX1 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $73,296.74 | 2,102 | BMVNDH9 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $73,037.52 | 2,248 | BJQ05Z6 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $71,972.52 | 1,758 | BQKXDX4 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $71,678.94 | 1,093 | BDRW1L7 |
| 0.09% | QURE | UNIQURE NV | -- | $71,411.40 | 2,454 | BJFSR88 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $70,883.93 | 3,473 | BN7Q7R7 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $70,457.20 | 2,948 | BPCQZY9 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $70,198.50 | 883 | BCDWBX6 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $69,899.48 | 1,877 | BR3T9B6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,711.85 | 2,279 | BKSGZN7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $68,673.15 | 2,535 | BBC9WC7 |
| 0.09% | INVA | INNOVIVA INC | -- | $66,309.84 | 2,916 | BDDXF67 |
| 0.08% | VCEL | VERICEL CORP | -- | $65,847.06 | 1,999 | BSBMN89 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $65,536.52 | 2,306 | BCBVTX1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $65,306.68 | 1,766 | BQXJKH2 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,053.50 | 4,650 | BYZM6C2 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $64,738.80 | 20,552 | BM9FJ13 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $64,638.00 | 4,050 | BMVLGP2 |
| 0.08% | ARDX | ARDELYX INC | -- | $63,819.55 | 9,655 | BN89V40 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $62,467.44 | 4,326 | BPCK358 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $62,039.15 | 571 | BNSP8K3 |
| 0.08% | NVAX | NOVAVAX INC | -- | $61,693.06 | 6,413 | BJDQXG4 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $59,340.85 | 14,299 | BWJDYK1 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,083.20 | 11,936 | BL53SR3 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $58,148.40 | 6,186 | BK4PZ38 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,743.20 | 16,220 | BF0DMK7 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $57,387.33 | 3,003 | BP7KZP7 |
| 0.07% | PGEN | PRECIGEN INC | -- | $56,850.72 | 13,934 | BKM5C84 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $55,838.10 | 2,495 | BQB42F1 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $54,891.60 | 1,842 | BZ7PJQ1 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $53,779.41 | 3,681 | BRXYZ57 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $53,192.70 | 1,990 | BD06CS0 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $52,643.76 | 2,444 | BP6C0S2 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,934.44 | 3,252 | BYP80F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $50,571.80 | 1,726 | BLCD809 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $50,334.27 | 7,413 | BYZG9R0 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $48,827.32 | 1,894 | BSRK699 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $47,163.16 | 1,628 | BMGTLY5 |
| 0.06% | ALVO | ALVOTECH SA | -- | $46,167.75 | 13,005 | BPNTJ34 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,612.50 | 1,250 | BX7RSN3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $44,387.58 | 3,259 | BMGS7L1 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $44,075.35 | 3,155 | BMZ4LN0 |
| 0.06% | SEPN | SEPTERNA INC | -- | $43,743.24 | 1,761 | BQNKXX2 |
| 0.05% | HROW | HARROW INC | -- | $42,412.83 | 1,461 | BHNDW86 |
| 0.05% | OMER | OMEROS CORP | -- | $41,180.40 | 2,790 | B4NB858 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $41,136.52 | 2,147 | BQB42H3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,902.84 | 6,534 | BLR7H87 |
| 0.05% | SVRA | SAVARA INC | -- | $40,716.20 | 8,015 | BYXGN81 |
| 0.05% | MNKD | MANNKIND CORP | -- | $39,792.96 | 12,132 | BF081J4 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $38,868.06 | 3,102 | BJLKVS6 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,597.20 | 2,328 | BM90J52 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $36,338.44 | 1,591 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $36,295.56 | 4,801 | B8K7T65 |
| 0.05% | XNCR | XENCOR INC | -- | $35,939.16 | 2,889 | BGCYWN8 |
| 0.05% | DSGN | DESIGN THERAPEUTICS INC | -- | $35,385.39 | 2,241 | BMFK3H6 |
| 0.05% | GERN | GERON CORP | -- | $35,189.00 | 25,135 | 2370381 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $34,896.16 | 3,952 | BKVDFF7 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $34,800.18 | 3,714 | BMC3HS7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $34,540.77 | 2,397 | BMFX8Y7 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $34,194.14 | 10,489 | BMFJJ97 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,596.59 | 3,893 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,163.68 | 3,426 | BYZD465 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $32,894.08 | 1,996 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,635.32 | 7,572 | BZ0QMB7 |
| 0.04% | ABSI | ABSCI CORP | -- | $31,706.96 | 5,921 | BN94K69 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,344.05 | 1,055 | BGL0JK3 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $31,255.00 | 1,786 | BNFWZS4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,086.71 | 1,709 | BT9K6D8 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,014.72 | 3,168 | BFYQFJ2 |
| 0.04% | ANNX | ANNEXON INC | -- | $31,002.56 | 5,699 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $29,731.96 | 2,059 | BQS7491 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $29,666.38 | 811 | BL95N25 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,456.43 | 9,411 | BBNBTD2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,961.39 | 1,637 | BRJJYT3 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $26,860.24 | 5,764 | BMCWKZ2 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $26,345.97 | 1,349 | BD9GVY0 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,204.63 | 6,407 | B3MZ6K5 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $25,879.60 | 6,670 | BYWVTY5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,096.16 | 2,878 | BP0TQC5 |
| 0.03% | PSNL | PERSONALIS INC | -- | $24,878.76 | 4,119 | BJQ0608 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,486.80 | 2,216 | BLFBZ32 |
| 0.03% | ARVN | ARVINAS INC | -- | $24,097.26 | 2,518 | BDZ30Q0 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,700.40 | 3,070 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $23,453.10 | 7,107 | BPBJFM7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,296.02 | 3,102 | BJ0LT31 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $23,165.36 | 4,747 | BYV2W40 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,007.27 | 2,249 | BSMLR16 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,797.10 | 1,170 | BKLCWZ3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,058.29 | 717 | BQD3J33 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,752.38 | 2,007 | BKLXFX5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,718.36 | 741 | BPBPCG8 |
| 0.03% | RGNX | REGENXBIO INC | -- | $20,408.32 | 1,993 | BZ0G875 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,355.00 | 8,850 | BFZNYB7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,976.32 | 4,802 | BYVQJ96 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $19,963.31 | 2,117 | B91XRN2 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $19,825.00 | 2,500 | BP81R42 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $19,466.33 | 1,093 | BS2CR64 |
| 0.02% | NGNE | NEUROGENE INC | -- | $19,207.86 | 609 | BS2F741 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,152.96 | 2,272 | B2Q9833 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $19,036.65 | 2,127 | BRCFFK6 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,249.12 | 2,622 | BJDX8Z9 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,655.75 | 4,275 | BMXNGZ6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $16,907.00 | 3,074 | BLN9Z50 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,622.32 | 1,144 | B9L5200 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,588.00 | 2,552 | BDRJH21 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,378.34 | 1,199 | BPRBTY7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $16,376.10 | 2,873 | BQ6C357 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,255.90 | 10,910 | BM8NHS1 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $16,112.25 | 837 | BTNMG41 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,960.72 | 584 | B292NQ7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,564.64 | 4,276 | BDFKQ07 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,219.20 | 11,890 | B4N8MH9 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,184.40 | 4,930 | BFY7DC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $15,016.38 | 2,339 | B12W3P6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,167.08 | 2,001 | B7F2TY6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $13,980.00 | 1,200 | BM7V485 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,750.44 | 3,788 | BK5MWR1 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $13,300.68 | 3,252 | BDDVW37 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,069.14 | 2,523 | BMVBZF5 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,640.00 | 7,900 | BFMLGR4 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $12,554.71 | 1,849 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,549.00 | 2,820 | 2107437 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $12,503.90 | 6,581 | BN4JN37 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,179.14 | 3,842 | BKX9NQ0 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,262.92 | 3,844 | BZ8FPH3 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,169.00 | 3,650 | BYTYP72 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $10,977.51 | 3,963 | BZC0D70 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,751.20 | 1,510 | BP81RK8 |
| 0.01% | OABI | OMNIAB INC | -- | $10,482.10 | 5,666 | BN13S71 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,065.06 | 5,886 | BRK0149 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,773.20 | 2,305 | BMF7DT9 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $9,737.21 | 1,231 | BQV0J03 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,636.30 | 2,322 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,340.65 | 1,221 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,231.75 | 1,119 | BKC9SX3 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $9,103.14 | 4,419 | BKRRKY7 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,032.24 | 3,556 | B5LL2C2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,021.32 | 2,222 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,599.84 | 1,822 | BKDQKM6 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $8,535.00 | 8,535 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,406.93 | 2,107 | BP7L561 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,468.37 | 3,679 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,266.98 | 7,694 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,916.91 | 7,601 | BMYTJP4 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,716.88 | 1,473 | 2517058 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $6,377.80 | 2,453 | BLBR8D5 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,344.86 | 2,242 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,106.98 | 2,922 | BPTK6Z2 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,242.38 | 858 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,549.44 | 2,708 | BMTX3D7 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,225.10 | 3,841 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,103.21 | 9,111 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 37.30% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,911,324 | -- | 4,820 | -- |
| 27.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,137,657 | -- | 3,524 | -- |
| 26.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,237,927 | -- | 3,374 | -- |
| 20.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,829,250 | -- | 2,639 | -- |
| 19.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 15,073,477 | -- | 2,513 | -- |
| 4.90% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,796,861 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $27,793,729.73 | 27,793,730 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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