BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,825,504
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/04/2026- NAV
- NAV Change
- Market Price $83.08
- Market Price Change $+3.71
- Trading Volume (M) 6,038
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,825,504
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/04/2026- NAV
- NAV Change
- Market Price $83.08
- Market Price Change $+3.71
- Trading Volume (M) 6,038
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/04/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.69% | AMGN | AMGEN INC | -- | $3,387,916.80 | 9,803 | 2023607 |
| 4.68% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,382,403.18 | 7,657 | 2931034 |
| 4.56% | GILD | GILEAD SCIENCES INC | -- | $3,299,515.56 | 25,542 | 2369174 |
| 3.34% | REGN | REGENERON PHARMACEUTICALS | -- | $2,414,323.20 | 3,840 | 2730190 |
| 2.06% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,489,050.56 | 4,904 | B00FWN1 |
| 1.58% | RVMD | REVOLUTION MEDICINES INC | -- | $1,140,584.94 | 7,326 | BL71K91 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,065,741.25 | 5,425 | 2455965 |
| 1.31% | ILMN | ILLUMINA INC | -- | $950,043.18 | 5,653 | 2613990 |
| 1.23% | UTHR | UNITED THERAPEUTICS CORP | -- | $887,257.80 | 1,620 | 2430412 |
| 1.22% | ARGX | ARGENX SE - ADR | -- | $884,383.50 | 1,050 | BDVLM39 |
| 1.21% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $871,351.74 | 15,837 | BMVP7Y0 |
| 1.16% | INSM | INSMED INC | -- | $836,002.56 | 7,968 | 2614487 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $781,363.80 | 26,460 | BMW4NZ9 |
| 1.04% | MRNA | MODERNA INC | -- | $753,214.00 | 14,600 | BGSXTS3 |
| 1.03% | INCY | INCYTE CORP | -- | $745,025.16 | 7,359 | 2471950 |
| 0.94% | VTRS | VIATRIS INC | -- | $676,783.50 | 42,565 | BMWS3X9 |
| 0.89% | GH | GUARDANT HEALTH INC | -- | $645,341.00 | 4,850 | BFXC911 |
| 0.86% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $621,203.20 | 3,712 | 2623911 |
| 0.76% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $546,136.50 | 2,275 | B4Q5ZN4 |
| 0.70% | EXEL | EXELIXIS INC | -- | $503,904.00 | 9,600 | 2576941 |
| 0.69% | ASND | ASCENDIS PHARMA A/S | -- | $498,079.84 | 2,276 | BWXJHM8 |
| 0.67% | BBIO | BRIDGEBIO PHARMA INC | -- | $482,554.11 | 7,167 | BK1KWG8 |
| 0.67% | MEDP | MEDPACE HOLDINGS INC | -- | $482,083.19 | 1,051 | BDCBC61 |
| 0.63% | IONS | IONIS PHARMACEUTICALS INC | -- | $458,969.17 | 6,109 | BDJ0LS6 |
| 0.61% | AXSM | AXSOME THERAPEUTICS INC | -- | $437,497.20 | 1,890 | BYZR4X4 |
| 0.59% | SMMT | SUMMIT THERAPEUTICS INC | -- | $425,373.76 | 28,664 | BMTVQS7 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $417,427.01 | 847 | BD59BS7 |
| 0.56% | SNY | SANOFI-ADR | -- | $401,505.86 | 9,047 | 2964557 |
| 0.56% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $401,501.70 | 7,110 | 2437071 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $389,178.48 | 5,178 | BYQBFJ8 |
| 0.52% | BNTX | BIONTECH SE-ADR | -- | $377,442.67 | 4,213 | BK6H543 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $335,718.24 | 6,424 | BSLSJJ0 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $332,413.20 | 1,080 | BD6JX35 |
| 0.46% | ONC | BEONE MEDICINES LTD-ADR | -- | $330,597.33 | 1,181 | BYYWPW6 |
| 0.46% | CYTK | CYTOKINETICS INC | -- | $329,136.37 | 4,553 | BBBSBJ5 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $312,462.40 | 4,364 | 2975098 |
| 0.38% | IBRX | IMMUNITYBIO INC | -- | $277,078.32 | 38,008 | BNSP0B8 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $272,427.75 | 1,029 | BQ721R4 |
| 0.37% | ALKS | ALKERMES PLC | -- | $267,350.94 | 6,163 | B3P6D26 |
| 0.36% | PCVX | VAXCYTE INC | -- | $259,451.96 | 5,321 | BKPVGH6 |
| 0.35% | NUVL | NUVALENT INC-A | -- | $254,324.10 | 2,705 | BMVBZD3 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $245,776.41 | 7,523 | BJRFSB7 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $242,687.19 | 2,361 | BDCBCD8 |
| 0.33% | ABVX | ABIVAX SA-ADR | -- | $238,296.03 | 2,271 | BLC89B2 |
| 0.32% | SYRE | SPYRE THERAPEUTICS INC | -- | $227,984.40 | 2,905 | BQBBDY8 |
| 0.31% | KYMR | KYMERA THERAPEUTICS INC | -- | $225,098.37 | 3,017 | BMPRZV5 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $221,302.86 | 2,526 | BF2YWG4 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $216,299.68 | 3,062 | B17VCN9 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $206,345.19 | 2,231 | BJDX8Y8 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $202,172.50 | 3,550 | BDHF4K6 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $196,805.58 | 6,002 | BLR6XK8 |
| 0.26% | APGE | APOGEE THERAPEUTICS INC | -- | $184,345.20 | 2,028 | BM9HHL5 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $180,247.68 | 10,431 | BT18HP9 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,035.40 | 4,423 | BLB0YQ9 |
| 0.24% | CGON | CG ONCOLOGY INC | -- | $175,169.07 | 3,123 | BRBCSP4 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $173,629.76 | 736 | 2501578 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,168.80 | 4,624 | BTZRLN8 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $171,030.09 | 3,773 | BFZQ0L8 |
| 0.23% | TWST | TWIST BIOSCIENCE CORP | -- | $167,525.38 | 2,266 | BGKG6G7 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $162,891.26 | 3,074 | BRJ3GY4 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $157,427.62 | 3,409 | BLFGJD5 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $157,264.64 | 11,632 | BFNF1D6 |
| 0.21% | ERAS | ERASCA INC | -- | $151,861.88 | 11,444 | BNLYBF3 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $147,654.18 | 3,966 | BKY5JZ8 |
| 0.20% | VCYT | VERACYTE INC | -- | $146,723.72 | 2,938 | BFTWZY0 |
| 0.20% | TXG | 10X GENOMICS INC-CLASS A | -- | $145,758.50 | 4,351 | BKS3RS7 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $138,912.84 | 4,252 | BP8JSP4 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $136,901.16 | 6,303 | 2713317 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $134,087.36 | 3,872 | BDD19F8 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $123,708.28 | 3,767 | BK6L288 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $118,080.82 | 5,863 | BD2B4V0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $112,492.80 | 2,880 | BQS9486 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $112,061.67 | 6,087 | BN15WD1 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $111,418.92 | 1,789 | BKVF0J2 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $110,262.70 | 4,978 | BP2P6L0 |
| 0.15% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $106,772.40 | 3,122 | BMX9K07 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $102,911.36 | 5,692 | BJ5FZ74 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $100,684.65 | 4,587 | BKX9VD3 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $100,336.21 | 1,411 | BMGJZJ8 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $96,051.24 | 6,606 | BN2R582 |
| 0.13% | GRAL | GRAIL INC | -- | $95,765.45 | 1,439 | BSLSSX7 |
| 0.13% | ALMS | ALUMIS INC | -- | $95,302.86 | 4,674 | BPLQG36 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $94,914.82 | 1,573 | BMH5RL1 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $94,848.12 | 3,246 | BK0VHF6 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $94,764.00 | 2,120 | B72ZBG4 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $90,614.15 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $87,989.68 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $83,592.54 | 1,698 | BRXB0C0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $83,240.01 | 3,571 | BJ62Z18 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $80,442.18 | 4,914 | BFWLC09 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $78,525.37 | 9,271 | 2100362 |
| 0.11% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $77,936.04 | 2,196 | BMFD115 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $77,030.80 | 2,255 | BFXC933 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $75,719.91 | 4,209 | BYSS4X4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $74,868.21 | 2,367 | BMZ2X38 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $73,328.60 | 19,297 | BM9FJ13 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $73,271.25 | 2,925 | BP9N0G0 |
| 0.10% | ABCL | ABCELLERA BIOLOGICS INC | -- | $71,401.33 | 11,209 | BL53SR3 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,831.20 | 8,049 | BNZB1X8 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $70,534.40 | 2,140 | BKSGZN7 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $70,263.90 | 8,805 | B9NSBM2 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $69,426.60 | 2,766 | BPCQZY9 |
| 0.09% | VCEL | VERICEL CORP | -- | $66,918.75 | 1,875 | BSBMN89 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,716.16 | 15,232 | BF0DMK7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $66,132.36 | 1,764 | BR3T9B6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $66,056.06 | 4,742 | BJH9ZN0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $65,736.00 | 830 | BCDWBX6 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $64,557.50 | 3,875 | B8DPDT7 |
| 0.09% | QURE | UNIQURE NV | -- | $64,516.95 | 2,305 | BJFSR88 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,442.75 | 4,369 | BYZM6C2 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $63,583.32 | 2,111 | BJQ05Z6 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $62,374.78 | 1,651 | BQKXDX4 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,359.14 | 2,166 | BCBVTX1 |
| 0.08% | NVAX | NOVAVAX INC | -- | $61,374.37 | 6,023 | BJDQXG4 |
| 0.08% | INVA | INNOVIVA INC | -- | $60,718.40 | 2,740 | BDDXF67 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $60,430.50 | 13,429 | BWJDYK1 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,653.92 | 10,128 | BNC1BX1 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $59,598.75 | 3,455 | BRXYZ57 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $58,832.67 | 2,379 | BBC9WC7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $58,763.22 | 3,261 | BN7Q7R7 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $58,094.56 | 3,802 | BMVLGP2 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $58,084.29 | 4,059 | BPCK358 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $53,653.32 | 1,974 | BMVNDH9 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,335.50 | 2,294 | BP6C0S2 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $53,161.50 | 5,810 | BK4PZ38 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $52,858.41 | 1,023 | BDRW1L7 |
| 0.07% | SEPN | SEPTERNA INC | -- | $51,980.09 | 1,657 | BQNKXX2 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $51,248.78 | 1,658 | BQXJKH2 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $50,528.43 | 1,527 | BMGTLY5 |
| 0.07% | PGEN | PRECIGEN INC | -- | $50,488.80 | 13,080 | BKM5C84 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,396.50 | 1,870 | BD06CS0 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $49,001.25 | 537 | BNSP8K3 |
| 0.07% | ARDX | ARDELYX INC | -- | $48,956.40 | 9,066 | BN89V40 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $48,920.48 | 2,818 | BP7KZP7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $47,820.63 | 2,343 | BQB42F1 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $47,748.00 | 1,730 | BZ7PJQ1 |
| 0.07% | HROW | HARROW INC | -- | $47,525.30 | 1,370 | BHNDW86 |
| 0.06% | PSNL | PERSONALIS INC | -- | $46,814.90 | 3,869 | BJQ0608 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,619.96 | 1,621 | BLCD809 |
| 0.06% | ALVO | ALVOTECH SA | -- | $45,665.40 | 12,210 | BPNTJ34 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $45,505.35 | 3,487 | BMC3HS7 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $45,161.20 | 1,778 | BSRK699 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $42,386.40 | 6,960 | BYZG9R0 |
| 0.06% | ABSI | ABSCI CORP | -- | $40,817.74 | 5,561 | BN94K69 |
| 0.06% | MNKD | MANNKIND CORP | -- | $40,089.28 | 11,389 | BF081J4 |
| 0.06% | SVRA | SAVARA INC | -- | $39,877.20 | 7,524 | BYXGN81 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $38,312.68 | 1,172 | BX7RSN3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $37,724.10 | 6,134 | BLR7H87 |
| 0.05% | EYPT | EYEPOINT INC | -- | $37,540.12 | 3,062 | BMGS7L1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,447.54 | 1,983 | BQB42H3 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,792.88 | 3,054 | BYP80F1 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,185.80 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,891.65 | 1,495 | B3X26D8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,159.92 | 3,656 | BMCR7V2 |
| 0.05% | XNCR | XENCOR INC | -- | $32,559.11 | 2,711 | BGCYWN8 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $31,634.16 | 2,962 | BMZ4LN0 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,529.55 | 2,185 | BM90J52 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $31,359.90 | 1,677 | BNFWZS4 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,973.76 | 2,251 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,928.50 | 7,110 | BZ0QMB7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,693.75 | 1,875 | BMNDK09 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $30,133.11 | 3,053 | BDDVW37 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $29,762.22 | 3,711 | BKVDFF7 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $29,153.04 | 9,849 | BMFJJ97 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,152.05 | 5,349 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,874.62 | 1,934 | BQS7491 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,712.32 | 2,912 | BJLKVS6 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $28,668.80 | 992 | BGL0JK3 |
| 0.04% | GERN | GERON CORP | -- | $28,558.42 | 23,602 | 2370381 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,470.75 | 2,975 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,221.86 | 3,218 | BYZD465 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $27,300.08 | 1,604 | BT9K6D8 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $26,995.90 | 5,410 | BMCWKZ2 |
| 0.04% | OMER | OMEROS CORP | -- | $26,875.50 | 2,622 | B4NB858 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,209.52 | 763 | BL95N25 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,093.89 | 2,707 | BP0TQC5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,859.94 | 2,911 | BJ0LT31 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,760.00 | 1,100 | BKLCWZ3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,267.11 | 2,083 | BLFBZ32 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $23,155.31 | 6,673 | BPBJFM7 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,649.80 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $22,004.46 | 1,269 | BD9GVY0 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $21,995.52 | 1,536 | BRJJYT3 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,001.89 | 4,459 | BYV2W40 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,851.20 | 2,880 | BQHN6C7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $20,495.20 | 6,028 | B3MZ6K5 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,328.00 | 672 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,187.09 | 693 | BPBPCG8 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $19,922.70 | 6,265 | BYWVTY5 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,868.85 | 1,885 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,675.54 | 4,511 | BYVQJ96 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $18,618.60 | 1,023 | BS2CR64 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $18,398.25 | 1,989 | B91XRN2 |
| 0.03% | ARVN | ARVINAS INC | -- | $18,289.62 | 2,363 | BDZ30Q0 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,195.69 | 11,163 | B4N8MH9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,948.32 | 8,308 | BFZNYB7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,790.40 | 2,112 | BSMLR16 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $15,973.20 | 2,349 | BP81R42 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,820.20 | 2,397 | BDRJH21 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,748.92 | 2,134 | B2Q9833 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,691.08 | 571 | BS2F741 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,404.28 | 548 | B292NQ7 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,049.53 | 3,609 | BKX9NQ0 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $14,837.71 | 1,997 | BRCFFK6 |
| 0.02% | OABI | OMNIAB INC | -- | $14,156.52 | 5,322 | BN13S71 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,870.16 | 1,124 | BPRBTY7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,662.50 | 2,186 | B12W3P6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,522.52 | 4,631 | BFY7DC4 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,206.06 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,171.79 | 1,879 | B7F2TY6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,891.66 | 2,697 | BQ6C357 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,886.24 | 1,873 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,769.38 | 2,889 | BLN9Z50 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,574.56 | 1,072 | B9L5200 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,485.07 | 3,557 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,307.24 | 7,414 | BFMLGR4 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,116.25 | 1,125 | BM7V485 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,891.60 | 1,736 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,721.78 | 2,646 | 2107437 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,717.96 | 4,013 | BDFKQ07 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,370.84 | 10,244 | BM8NHS1 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,808.00 | 6,176 | BN4JN37 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,796.89 | 3,611 | BZ8FPH3 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $10,756.83 | 1,981 | BP7L561 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,693.76 | 2,387 | BMVBZF5 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,632.64 | 7,136 | BMYTJP4 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,270.35 | 787 | BTNMG41 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,912.00 | 1,416 | BP81RK8 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,661.32 | 3,426 | BYTYP72 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,354.80 | 3,341 | B5LL2C2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $9,254.40 | 7,230 | BNR5QT9 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,930.40 | 3,721 | BZC0D70 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,701.88 | 5,525 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,458.08 | 1,052 | BKC9SX3 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,337.60 | 1,158 | BQV0J03 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,335.11 | 2,089 | BPRB2N7 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,303.68 | 2,464 | BJDX8Z9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,097.82 | 1,147 | BP2NYN2 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,097.10 | 2,165 | BMF7DT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,030.73 | 1,387 | 2517058 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,887.98 | 2,179 | BY7RB53 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,471.80 | 4,151 | BKRRKY7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,305.97 | 1,711 | BKDQKM6 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,132.51 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,186.07 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,760.30 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,399.45 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,938.13 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,760.68 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,242.15 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,167.76 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,521.08 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 32.15% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 23,237,832 | -- | 3,911 | -- |
| 28.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,938,410 | -- | 3,524 | -- |
| 27.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,047,161 | -- | 3,374 | -- |
| 21.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,680,041 | -- | 2,639 | -- |
| 20.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,931,392 | -- | 2,513 | -- |
| 5.20% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,761,071 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,219,779.93 | 21,219,780 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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