BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $72,370,352
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/16/2026- NAV
- NAV Change
- Market Price $83.11
- Market Price Change $-0.60
- Trading Volume (M) 4,469
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $72,370,352
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/16/2026- NAV
- NAV Change
- Market Price $83.11
- Market Price Change $-0.60
- Trading Volume (M) 4,469
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/16/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.79% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,469,922.69 | 7,657 | 2931034 |
| 4.71% | AMGN | AMGEN INC | -- | $3,409,875.52 | 9,803 | 2023607 |
| 4.49% | GILD | GILEAD SCIENCES INC | -- | $3,249,708.66 | 25,542 | 2369174 |
| 3.26% | REGN | REGENERON PHARMACEUTICALS | -- | $2,360,563.20 | 3,840 | 2730190 |
| 1.91% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,382,437.60 | 4,904 | B00FWN1 |
| 1.59% | RVMD | REVOLUTION MEDICINES INC | -- | $1,147,105.08 | 7,326 | BL71K91 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,061,184.25 | 5,425 | 2455965 |
| 1.28% | ILMN | ILLUMINA INC | -- | $928,674.84 | 5,653 | 2613990 |
| 1.27% | ARGX | ARGENX SE - ADR | -- | $922,414.50 | 1,050 | BDVLM39 |
| 1.23% | UTHR | UNITED THERAPEUTICS CORP | -- | $888,197.40 | 1,620 | 2430412 |
| 1.19% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $858,523.77 | 15,837 | BMVP7Y0 |
| 1.12% | MRNA | MODERNA INC | -- | $808,840.00 | 14,600 | BGSXTS3 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $804,648.60 | 26,460 | BMW4NZ9 |
| 1.05% | INSM | INSMED INC | -- | $761,103.36 | 7,968 | 2614487 |
| 1.01% | INCY | INCYTE CORP | -- | $734,060.25 | 7,359 | 2471950 |
| 0.94% | VTRS | VIATRIS INC | -- | $682,742.60 | 42,565 | BMWS3X9 |
| 0.85% | GH | GUARDANT HEALTH INC | -- | $617,599.00 | 4,850 | BFXC911 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $580,631.04 | 3,712 | 2623911 |
| 0.73% | ASND | ASCENDIS PHARMA A/S | -- | $526,211.20 | 2,276 | BWXJHM8 |
| 0.71% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $516,152.00 | 2,275 | B4Q5ZN4 |
| 0.69% | EXEL | EXELIXIS INC | -- | $500,160.00 | 9,600 | 2576941 |
| 0.67% | MEDP | MEDPACE HOLDINGS INC | -- | $485,141.60 | 1,051 | BDCBC61 |
| 0.66% | BBIO | BRIDGEBIO PHARMA INC | -- | $477,608.88 | 7,167 | BK1KWG8 |
| 0.66% | AXSM | AXSOME THERAPEUTICS INC | -- | $476,109.90 | 1,890 | BYZR4X4 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $446,506.81 | 6,109 | BDJ0LS6 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $424,507.93 | 847 | BD59BS7 |
| 0.55% | SNY | SANOFI-ADR | -- | $398,520.35 | 9,047 | 2964557 |
| 0.55% | SMMT | SUMMIT THERAPEUTICS INC | -- | $397,856.32 | 28,664 | BMTVQS7 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $396,375.90 | 5,178 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $391,903.20 | 7,110 | 2437071 |
| 0.52% | BNTX | BIONTECH SE-ADR | -- | $377,063.50 | 4,213 | BK6H543 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $349,239.60 | 1,080 | BD6JX35 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $342,431.13 | 4,553 | BBBSBJ5 |
| 0.46% | NUVL | NUVALENT INC-A | -- | $333,769.95 | 2,705 | BMVBZD3 |
| 0.45% | TEM | TEMPUS AI INC-CL A | -- | $324,797.44 | 6,424 | BSLSJJ0 |
| 0.43% | ONC | BEONE MEDICINES LTD-ADR | -- | $311,689.52 | 1,181 | BYYWPW6 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $303,908.96 | 4,364 | 2975098 |
| 0.38% | ALKS | ALKERMES PLC | -- | $271,726.67 | 6,163 | B3P6D26 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $264,710.25 | 1,029 | BQ721R4 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $263,806.48 | 3,017 | BMPRZV5 |
| 0.36% | PCVX | VAXCYTE INC | -- | $262,378.51 | 5,321 | BKPVGH6 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $261,221.04 | 2,361 | BDCBCD8 |
| 0.35% | IBRX | IMMUNITYBIO INC | -- | $255,413.76 | 38,008 | BNSP0B8 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $252,848.03 | 7,523 | BJRFSB7 |
| 0.33% | SYRE | SPYRE THERAPEUTICS INC | -- | $242,306.05 | 2,905 | BQBBDY8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $226,632.72 | 2,526 | BF2YWG4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $226,558.05 | 2,231 | BJDX8Y8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $224,352.74 | 3,062 | B17VCN9 |
| 0.31% | ABVX | ABIVAX SA-ADR | -- | $221,422.50 | 2,271 | BLC89B2 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $198,486.14 | 6,002 | BLR6XK8 |
| 0.27% | TWST | TWIST BIOSCIENCE CORP | -- | $192,496.70 | 2,266 | BGKG6G7 |
| 0.26% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $189,020.00 | 11,632 | BFNF1D6 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $188,254.44 | 3,123 | BRBCSP4 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $187,864.00 | 736 | 2501578 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $187,549.38 | 10,431 | BT18HP9 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,671.00 | 3,550 | BDHF4K6 |
| 0.25% | TVTX | TRAVERE THERAPEUTICS INC | -- | $181,972.42 | 3,409 | BLFGJD5 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,814.25 | 4,423 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $175,758.24 | 4,624 | BTZRLN8 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $172,866.72 | 2,028 | BM9HHL5 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $171,897.88 | 3,773 | BFZQ0L8 |
| 0.22% | TNGX | TANGO THERAPEUTICS INC | -- | $160,092.48 | 4,978 | BP2P6L0 |
| 0.22% | XENE | XENON PHARMACEUTICALS INC | -- | $159,817.26 | 3,074 | BRJ3GY4 |
| 0.21% | ERAS | ERASCA INC | -- | $153,120.72 | 11,444 | BNLYBF3 |
| 0.21% | VCYT | VERACYTE INC | -- | $149,602.96 | 2,938 | BFTWZY0 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $138,144.25 | 4,351 | BKS3RS7 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $135,520.00 | 3,872 | BDD19F8 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $134,645.70 | 3,966 | BKY5JZ8 |
| 0.18% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $131,984.82 | 6,303 | 2713317 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $128,575.59 | 5,863 | BD2B4V0 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $128,367.88 | 4,252 | BP8JSP4 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $123,580.80 | 2,880 | BQS9486 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $121,133.19 | 1,789 | BKVF0J2 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,748.29 | 4,587 | BKX9VD3 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $116,739.33 | 3,767 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $109,992.09 | 6,087 | BN15WD1 |
| 0.14% | ALMS | ALUMIS INC | -- | $104,323.68 | 4,674 | BPLQG36 |
| 0.14% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $104,212.36 | 3,122 | BMX9K07 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $99,420.30 | 6,606 | BN2R582 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $99,230.22 | 3,246 | BK0VHF6 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $98,530.13 | 1,411 | BMGJZJ8 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $98,016.24 | 5,692 | BJ5FZ74 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $95,638.40 | 1,573 | BMH5RL1 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $93,439.80 | 2,196 | BMFD115 |
| 0.13% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $92,389.60 | 2,120 | B72ZBG4 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $89,029.60 | 3,685 | BV2DHY6 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $88,805.40 | 1,698 | BRXB0C0 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $88,754.12 | 2,636 | BL55460 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $88,739.35 | 3,571 | BJ62Z18 |
| 0.12% | GRAL | GRAIL INC | -- | $83,879.31 | 1,439 | BSLSSX7 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $82,697.32 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $79,705.08 | 4,914 | BFWLC09 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $75,546.90 | 8,805 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $74,465.82 | 2,367 | BMZ2X38 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $74,279.70 | 2,255 | BFXC933 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $73,615.41 | 4,209 | BYSS4X4 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $73,026.80 | 4,742 | BJH9ZN0 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,396.20 | 2,140 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $72,112.50 | 1,875 | BSBMN89 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,958.06 | 8,049 | BNZB1X8 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $70,170.75 | 2,925 | BP9N0G0 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $68,965.44 | 2,166 | BCBVTX1 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,890.00 | 830 | BCDWBX6 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $67,896.36 | 1,764 | BR3T9B6 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $66,469.22 | 1,658 | BQXJKH2 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $64,900.14 | 3,802 | BMVLGP2 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $63,568.95 | 4,369 | BYZM6C2 |
| 0.09% | QURE | UNIQURE NV | -- | $62,211.95 | 2,305 | BJFSR88 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $62,207.34 | 2,766 | BPCQZY9 |
| 0.09% | PGEN | PRECIGEN INC | -- | $62,130.00 | 13,080 | BKM5C84 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,951.40 | 2,740 | BDDXF67 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $61,535.65 | 2,111 | BJQ05Z6 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $61,364.46 | 19,297 | BM9FJ13 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $61,147.50 | 3,875 | B8DPDT7 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $61,087.95 | 4,059 | BPCK358 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $60,491.55 | 3,261 | BN7Q7R7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,248.80 | 10,128 | BNC1BX1 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $58,935.03 | 1,023 | BDRW1L7 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $58,856.46 | 2,379 | BBC9WC7 |
| 0.08% | SEPN | SEPTERNA INC | -- | $58,276.69 | 1,657 | BQNKXX2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $58,186.24 | 15,232 | BF0DMK7 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $57,372.25 | 1,651 | BQKXDX4 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $57,053.81 | 11,209 | BL53SR3 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $55,686.54 | 1,974 | BMVNDH9 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $55,596.06 | 13,429 | BWJDYK1 |
| 0.08% | NVAX | NOVAVAX INC | -- | $55,411.60 | 6,023 | BJDQXG4 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $55,273.50 | 1,730 | BZ7PJQ1 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $55,210.90 | 3,455 | BRXYZ57 |
| 0.07% | HROW | HARROW INC | -- | $52,608.00 | 1,370 | BHNDW86 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $51,428.85 | 2,343 | BQB42F1 |
| 0.07% | ARDX | ARDELYX INC | -- | $51,404.22 | 9,066 | BN89V40 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $50,047.68 | 2,818 | BP7KZP7 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,024.10 | 5,810 | BK4PZ38 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,000.07 | 537 | BNSP8K3 |
| 0.07% | ALVO | ALVOTECH SA | -- | $47,252.70 | 12,210 | BPNTJ34 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,313.91 | 1,527 | BMGTLY5 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $45,834.12 | 2,294 | BP6C0S2 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,663.57 | 1,621 | BLCD809 |
| 0.06% | MNKD | MANNKIND CORP | -- | $44,075.43 | 11,389 | BF081J4 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $42,423.08 | 1,778 | BSRK699 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,324.60 | 6,134 | BLR7H87 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,609.80 | 1,172 | BX7RSN3 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $40,065.63 | 3,487 | BMC3HS7 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $39,950.40 | 6,960 | BYZG9R0 |
| 0.06% | SVRA | SAVARA INC | -- | $39,877.20 | 7,524 | BYXGN81 |
| 0.05% | EYPT | EYEPOINT INC | -- | $39,438.56 | 3,062 | BMGS7L1 |
| 0.05% | ABSI | ABSCI CORP | -- | $38,927.00 | 5,561 | BN94K69 |
| 0.05% | PSNL | PERSONALIS INC | -- | $37,490.61 | 3,869 | BJQ0608 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,070.77 | 1,983 | BQB42H3 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,853.96 | 3,054 | BYP80F1 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,463.20 | 3,656 | BMCR7V2 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,230.90 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,115.90 | 1,495 | B3X26D8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $33,472.92 | 1,677 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $33,074.20 | 2,711 | BGCYWN8 |
| 0.05% | BIOA | BIOAGE LABS INC | -- | $32,865.96 | 1,604 | BT9K6D8 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,091.20 | 992 | BGL0JK3 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,293.75 | 1,875 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,212.90 | 7,110 | BZ0QMB7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,838.70 | 2,251 | BMFX8Y7 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $30,838.41 | 3,711 | BKVDFF7 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $30,372.16 | 2,912 | BJLKVS6 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $30,249.20 | 3,218 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,606.75 | 2,185 | BM90J52 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,887.25 | 2,975 | BFYQFJ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,924.92 | 8,837 | BBNBTD2 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $27,872.67 | 9,849 | BMFJJ97 |
| 0.04% | GERN | GERON CORP | -- | $27,850.36 | 23,602 | 2370381 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $27,220.78 | 2,962 | BMZ4LN0 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,104.10 | 5,410 | BMCWKZ2 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $26,805.34 | 3,053 | BDDVW37 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,592.50 | 1,934 | BQS7491 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,349.95 | 2,083 | BLFBZ32 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,209.26 | 2,911 | BJ0LT31 |
| 0.03% | OMER | OMEROS CORP | -- | $24,856.56 | 2,622 | B4NB858 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,316.81 | 763 | BL95N25 |
| 0.03% | ANNX | ANNEXON INC | -- | $24,177.48 | 5,349 | BMVV9R5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,565.60 | 2,105 | BMFK3H6 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,506.00 | 1,100 | BKLCWZ3 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $22,499.37 | 1,269 | BD9GVY0 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,062.48 | 6,028 | B3MZ6K5 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,813.12 | 672 | BQD3J33 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $21,672.96 | 1,536 | BRJJYT3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,574.79 | 2,707 | BP0TQC5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,796.93 | 693 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,361.60 | 2,880 | BQHN6C7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,352.06 | 4,459 | BYV2W40 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,216.86 | 4,511 | BYVQJ96 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,151.51 | 6,673 | BPBJFM7 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,356.45 | 6,265 | BYWVTY5 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,534.22 | 1,023 | BS2CR64 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,533.46 | 2,363 | BDZ30Q0 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,758.85 | 571 | BS2F741 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,727.04 | 2,112 | BSMLR16 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,488.81 | 1,989 | B91XRN2 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,342.95 | 1,885 | BKLXFX5 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,919.64 | 2,134 | B2Q9833 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,892.11 | 2,397 | BDRJH21 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,785.20 | 8,308 | BFZNYB7 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,442.64 | 548 | B292NQ7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,070.05 | 11,163 | B4N8MH9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,751.72 | 2,349 | BP81R42 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,937.60 | 1,124 | BPRBTY7 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,858.56 | 3,609 | BKX9NQ0 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,647.60 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,472.43 | 1,879 | B7F2TY6 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,979.89 | 1,873 | BZ0G875 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,939.04 | 1,072 | B9L5200 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,810.75 | 2,697 | BQ6C357 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,525.78 | 2,186 | B12W3P6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,307.14 | 2,889 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,133.22 | 4,631 | BFY7DC4 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $11,822.24 | 1,997 | BRCFFK6 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,648.56 | 1,736 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,377.80 | 2,646 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,283.75 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,236.40 | 4,013 | BDFKQ07 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,046.86 | 7,414 | BFMLGR4 |
| 0.01% | OABI | OMNIAB INC | -- | $10,750.44 | 5,322 | BN13S71 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $9,959.60 | 3,557 | BK5MWR1 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,790.28 | 787 | BTNMG41 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,786.70 | 2,387 | BMVBZF5 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,634.56 | 6,176 | BN4JN37 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,204.00 | 1,416 | BP81RK8 |
| 0.01% | IVVD | INVIVYD INC | -- | $9,135.60 | 10,244 | BM8NHS1 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,132.41 | 1,981 | BP7L561 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,818.77 | 3,721 | BZC0D70 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,681.65 | 2,165 | BMF7DT9 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,633.52 | 3,426 | BYTYP72 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,525.44 | 2,464 | BJDX8Z9 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,521.96 | 3,611 | BZ8FPH3 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,285.68 | 3,341 | B5LL2C2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,042.65 | 2,089 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,691.87 | 2,179 | BY7RB53 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,624.50 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,550.16 | 1,158 | BQV0J03 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,511.28 | 1,052 | BKC9SX3 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,420.45 | 1,387 | 2517058 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,350.08 | 7,136 | BMYTJP4 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,226.10 | 1,147 | BP2NYN2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,897.42 | 7,230 | BNR5QT9 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,878.22 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,268.01 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,837.26 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,448.16 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,388.80 | 2,743 | BPTK6Z2 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,040.19 | 2,541 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,030.25 | 2,303 | BLBR8D5 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,536.40 | 2,105 | BKTV702 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,990.88 | 804 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,741.00 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,434.67 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.56% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,009,687 | -- | 4,201 | -- |
| 28.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,979,323 | -- | 3,524 | -- |
| 25.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,264,632 | -- | 3,068 | -- |
| 21.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,710,680 | -- | 2,639 | -- |
| 20.67% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,960,568 | -- | 2,513 | -- |
| 5.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,768,420 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,271,580.67 | 21,271,581 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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