BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,354,198
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/08/2026- NAV
- NAV Change
- Market Price $82.90
- Market Price Change $+0.38
- Trading Volume (M) 33,554
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,354,198
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/08/2026- NAV
- NAV Change
- Market Price $82.90
- Market Price Change $+0.38
- Trading Volume (M) 33,554
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/08/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.77% | GILD | GILEAD SCIENCES INC | -- | $3,693,130.93 | 28,121 | 2369174 |
| 4.68% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,622,952.78 | 8,429 | 2931034 |
| 4.63% | AMGN | AMGEN INC | -- | $3,579,374.70 | 10,791 | 2023607 |
| 3.91% | REGN | REGENERON PHARMACEUTICALS | -- | $3,021,840.03 | 4,227 | 2730190 |
| 2.06% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,592,089.80 | 5,396 | B00FWN1 |
| 1.49% | BIIB | BIOGEN INC | -- | $1,155,089.95 | 5,971 | 2455965 |
| 1.48% | RVMD | REVOLUTION MEDICINES INC | -- | $1,143,697.65 | 8,065 | BL71K91 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,007,288.02 | 1,783 | 2430412 |
| 1.17% | ARGX | ARGENX SE - ADR | -- | $903,406.35 | 1,155 | BDVLM39 |
| 1.15% | INSM | INSMED INC | -- | $889,143.55 | 8,773 | 2614487 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $885,574.44 | 17,436 | BMVP7Y0 |
| 1.14% | ILMN | ILLUMINA INC | -- | $883,061.12 | 6,224 | 2613990 |
| 1.13% | MRNA | MODERNA INC | -- | $873,567.55 | 16,073 | BGSXTS3 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $832,067.04 | 29,134 | BMW4NZ9 |
| 1.04% | VTRS | VIATRIS INC | -- | $804,672.05 | 46,865 | BMWS3X9 |
| 1.03% | INCY | INCYTE CORP | -- | $798,533.12 | 8,102 | 2471950 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $622,093.50 | 4,086 | 2623911 |
| 0.77% | ASND | ASCENDIS PHARMA A/S | -- | $597,843.30 | 2,505 | BWXJHM8 |
| 0.74% | SMMT | SUMMIT THERAPEUTICS INC | -- | $570,604.80 | 31,560 | BMTVQS7 |
| 0.73% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $565,603.95 | 2,505 | B4Q5ZN4 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $531,774.49 | 7,891 | BK1KWG8 |
| 0.66% | GH | GUARDANT HEALTH INC | -- | $510,750.90 | 5,337 | BFXC911 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $509,149.75 | 6,725 | BDJ0LS6 |
| 0.66% | EXEL | EXELIXIS INC | -- | $509,099.36 | 10,571 | 2576941 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $489,720.00 | 1,155 | BDCBC61 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $476,377.36 | 934 | BD59BS7 |
| 0.59% | AXSM | AXSOME THERAPEUTICS INC | -- | $452,585.16 | 2,082 | BYZR4X4 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $436,457.63 | 4,637 | BK6H543 |
| 0.56% | SNY | SANOFI-ADR | -- | $431,367.60 | 9,960 | 2964557 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $423,181.68 | 7,828 | 2437071 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $414,478.38 | 5,702 | BYQBFJ8 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $406,068.12 | 1,301 | BYYWPW6 |
| 0.50% | CYTK | CYTOKINETICS INC | -- | $385,626.74 | 5,014 | BBBSBJ5 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $374,242.68 | 1,134 | BQ721R4 |
| 0.47% | KRYS | KRYSTAL BIOTECH INC | -- | $364,406.32 | 1,192 | BD6JX35 |
| 0.46% | IBRX | IMMUNITYBIO INC | -- | $356,134.99 | 41,849 | BNSP0B8 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $352,510.20 | 7,070 | BSLSJJ0 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $313,734.40 | 2,980 | BMVBZD3 |
| 0.40% | PCVX | VAXCYTE INC | -- | $310,479.57 | 5,857 | BKPVGH6 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $308,032.48 | 4,804 | 2975098 |
| 0.40% | ABVX | ABIVAX SA-ADR | -- | $306,727.26 | 2,499 | BLC89B2 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $285,871.68 | 3,321 | BMPRZV5 |
| 0.34% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $263,184.96 | 2,456 | BJDX8Y8 |
| 0.34% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $261,792.60 | 2,780 | BF2YWG4 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $258,137.28 | 2,598 | BDCBCD8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $248,187.92 | 3,368 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $239,843.82 | 3,196 | BQBBDY8 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $239,825.78 | 8,287 | BJRFSB7 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $239,283.94 | 3,437 | BRBCSP4 |
| 0.31% | ALKS | ALKERMES PLC | -- | $237,372.16 | 6,784 | B3P6D26 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $229,561.92 | 6,608 | BLR6XK8 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $214,220.81 | 3,907 | BDHF4K6 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,479.09 | 5,203 | BYTQ6X1 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $201,012.06 | 4,154 | BFZQ0L8 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $200,976.00 | 5,088 | BTZRLN8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,763.71 | 4,869 | BLB0YQ9 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $191,105.84 | 3,386 | BRJ3GY4 |
| 0.24% | CAI | CARIS LIFE SCIENCES INC | -- | $185,498.90 | 11,486 | BT18HP9 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $185,239.93 | 2,231 | BM9HHL5 |
| 0.23% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $181,178.94 | 4,678 | BP8JSP4 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $179,342.10 | 810 | 2501578 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $169,039.20 | 12,806 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $159,963.00 | 3,755 | BLFGJD5 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $159,739.76 | 4,262 | BDD19F8 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $155,388.80 | 6,937 | 2713317 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $154,207.12 | 4,366 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $141,897.60 | 2,496 | BGKG6G7 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $134,031.04 | 4,147 | BK6L288 |
| 0.17% | VCYT | VERACYTE INC | -- | $130,839.54 | 3,237 | BFTWZY0 |
| 0.16% | ERAS | ERASCA INC | -- | $127,542.36 | 12,603 | BNLYBF3 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $127,242.30 | 1,970 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $126,627.48 | 6,454 | BD2B4V0 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $126,195.64 | 5,482 | BP2P6L0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $124,064.30 | 3,173 | BQS9486 |
| 0.16% | ALMS | ALUMIS INC | -- | $121,754.36 | 5,146 | BPLQG36 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $120,271.02 | 2,334 | B72ZBG4 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $117,987.00 | 6,700 | BN15WD1 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $109,582.00 | 1,870 | BRXB0C0 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $106,781.48 | 5,044 | BKX9VD3 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $106,076.04 | 1,554 | BMGJZJ8 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $106,015.72 | 1,732 | BMH5RL1 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $105,095.76 | 2,904 | BL55460 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $103,420.80 | 4,788 | BKS3RS7 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,729.96 | 3,933 | BJ62Z18 |
| 0.13% | KOD | KODIAK SCIENCES INC | -- | $101,868.84 | 2,484 | BFXC933 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $101,244.00 | 3,575 | BK0VHF6 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $98,492.75 | 2,417 | BMFD115 |
| 0.13% | GRAL | GRAIL INC | -- | $97,637.76 | 1,584 | BSLSSX7 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $96,592.20 | 3,435 | BMX9K07 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $95,177.88 | 3,222 | BP9N0G0 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $92,829.00 | 7,275 | BN2R582 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $89,478.90 | 4,058 | BV2DHY6 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $88,010.20 | 10,210 | 2100362 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $86,547.27 | 6,267 | BJ5FZ74 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $85,508.65 | 8,861 | BNZB1X8 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $85,128.03 | 4,266 | B8DPDT7 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $82,866.48 | 4,632 | BYSS4X4 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $82,424.76 | 5,412 | BFWLC09 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $80,410.14 | 1,818 | BQKXDX4 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $79,400.85 | 591 | BNSP8K3 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $79,208.15 | 9,695 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,474.72 | 2,608 | BMZ2X38 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $78,273.57 | 1,129 | BDRW1L7 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $77,170.59 | 3,591 | BN7Q7R7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $76,436.36 | 2,324 | BJQ05Z6 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $75,917.88 | 11,148 | BNC1BX1 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $75,661.00 | 5,218 | BJH9ZN0 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $74,802.09 | 1,826 | BQXJKH2 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,738.18 | 913 | BCDWBX6 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $74,543.04 | 2,172 | BMVNDH9 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $73,835.64 | 1,941 | BR3T9B6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,981.45 | 2,355 | BKSGZN7 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $72,816.72 | 3,048 | BPCQZY9 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $70,536.72 | 21,246 | BM9FJ13 |
| 0.09% | QURE | UNIQURE NV | -- | $70,145.76 | 2,536 | BJFSR88 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $69,273.03 | 2,621 | BBC9WC7 |
| 0.09% | VCEL | VERICEL CORP | -- | $69,161.82 | 2,067 | BSBMN89 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,152.72 | 4,186 | BMVLGP2 |
| 0.09% | INVA | INNOVIVA INC | -- | $68,990.46 | 3,014 | BDDXF67 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $67,744.72 | 4,808 | BYZM6C2 |
| 0.09% | ARDX | ARDELYX INC | -- | $67,671.18 | 9,981 | BN89V40 |
| 0.09% | NVAX | NOVAVAX INC | -- | $67,019.19 | 6,629 | BJDQXG4 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $66,251.36 | 2,384 | BCBVTX1 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $65,872.56 | 4,472 | BPCK358 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $64,661.60 | 12,340 | BL53SR3 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,700.16 | 16,768 | BF0DMK7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $60,640.84 | 14,404 | BKM5C84 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $60,205.95 | 3,105 | BP7KZP7 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $59,575.49 | 14,783 | BWJDYK1 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $58,711.15 | 3,805 | BRXYZ57 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $58,331.52 | 6,396 | BK4PZ38 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $58,233.82 | 2,579 | BQB42F1 |
| 0.07% | HROW | HARROW INC | -- | $57,765.53 | 1,511 | BHNDW86 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $55,977.60 | 1,904 | BZ7PJQ1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,020.34 | 7,663 | BYZG9R0 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $55,010.34 | 2,058 | BD06CS0 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $54,106.92 | 2,526 | BP6C0S2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $52,770.72 | 1,784 | BLCD809 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $52,279.10 | 3,362 | BYP80F1 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,966.74 | 1,958 | BSRK699 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $49,619.00 | 1,682 | BMGTLY5 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,837.60 | 1,292 | BX7RSN3 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $48,588.90 | 3,261 | BMZ4LN0 |
| 0.06% | EYPT | EYEPOINT INC | -- | $46,020.54 | 3,369 | BMGS7L1 |
| 0.06% | MNKD | MANNKIND CORP | -- | $44,147.84 | 12,542 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,103.62 | 6,754 | BLR7H87 |
| 0.06% | ALVO | ALVOTECH SA | -- | $43,830.70 | 13,445 | BPNTJ34 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $43,581.16 | 2,219 | BQB42H3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $43,467.27 | 1,821 | BQNKXX2 |
| 0.06% | SVRA | SAVARA INC | -- | $43,330.55 | 8,285 | BYXGN81 |
| 0.05% | OMER | OMEROS CORP | -- | $40,750.92 | 2,884 | B4NB858 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,200.30 | 4,963 | B8K7T65 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $38,984.96 | 3,206 | BJLKVS6 |
| 0.05% | XNCR | XENCOR INC | -- | $38,412.82 | 2,987 | BGCYWN8 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $38,081.75 | 1,645 | B3X26D8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $38,058.93 | 10,843 | BMFJJ97 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $38,054.40 | 3,840 | BMC3HS7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $36,161.10 | 4,086 | BKVDFF7 |
| 0.05% | GERN | GERON CORP | -- | $36,119.15 | 25,985 | 2370381 |
| 0.05% | ABSI | ABSCI CORP | -- | $36,113.90 | 6,121 | BN94K69 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,178.50 | 4,025 | BMCR7V2 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,111.48 | 2,477 | BMFX8Y7 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,108.64 | 2,064 | BMNDK09 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $35,074.00 | 1,846 | BNFWZS4 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,007.30 | 2,406 | BM90J52 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,973.52 | 7,828 | BZ0QMB7 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $33,560.00 | 839 | BL95N25 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,519.79 | 5,891 | BMVV9R5 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,365.64 | 3,542 | BYZD465 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $32,947.74 | 2,317 | BMFK3H6 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,348.15 | 1,091 | BGL0JK3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $32,170.32 | 3,276 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,788.33 | 1,767 | BT9K6D8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,381.46 | 2,129 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,549.06 | 9,729 | BBNBTD2 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $28,896.30 | 5,958 | BMCWKZ2 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $28,679.42 | 1,693 | BRJJYT3 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,949.06 | 6,623 | B3MZ6K5 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $27,446.08 | 6,896 | BYWVTY5 |
| 0.03% | ARVN | ARVINAS INC | -- | $26,326.44 | 2,604 | BDZ30Q0 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $25,947.00 | 1,395 | BD9GVY0 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,487.70 | 2,290 | BLFBZ32 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,468.82 | 4,259 | BJQ0608 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,391.52 | 3,206 | BJ0LT31 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $24,849.60 | 2,976 | BP0TQC5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $24,191.51 | 4,907 | BYV2W40 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,994.30 | 1,210 | BKLCWZ3 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $23,583.87 | 7,347 | BPBJFM7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,487.97 | 2,189 | B91XRN2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,074.98 | 3,174 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,185.00 | 765 | BPBPCG8 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $22,060.66 | 1,129 | BS2CR64 |
| 0.03% | RGNX | REGENXBIO INC | -- | $21,743.55 | 2,061 | BZ0G875 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,738.75 | 2,325 | BSMLR16 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $21,705.60 | 2,584 | BP81R42 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,444.48 | 4,964 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,040.50 | 2,075 | BKLXFX5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,857.44 | 9,148 | BFZNYB7 |
| 0.03% | KMDA | KAMADA LTD | -- | $20,075.40 | 2,348 | B2Q9833 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $19,988.91 | 2,199 | BRCFFK6 |
| 0.03% | NGNE | NEUROGENE INC | -- | $19,360.62 | 629 | BS2F741 |
| 0.02% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,295.64 | 741 | BQD3J33 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,997.10 | 2,710 | BJDX8Z9 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,131.88 | 1,182 | B9L5200 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,002.67 | 1,239 | BPRBTY7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,543.43 | 4,419 | BMXNGZ6 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,331.72 | 12,292 | B4N8MH9 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,320.93 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,268.36 | 604 | B292NQ7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,256.54 | 3,178 | BLN9Z50 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,917.00 | 11,278 | BM8NHS1 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,777.68 | 2,638 | BDRJH21 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $16,720.45 | 865 | BTNMG41 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,044.60 | 4,420 | BDFKQ07 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,746.64 | 5,096 | BFY7DC4 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,496.81 | 2,069 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $15,194.08 | 3,916 | BK5MWR1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $15,178.76 | 2,417 | B12W3P6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,966.80 | 1,240 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,996.80 | 2,916 | 2107437 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $13,683.34 | 3,362 | BDDVW37 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,618.98 | 2,609 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,319.67 | 1,911 | BL5B6Z1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,820.62 | 8,166 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,806.38 | 1,273 | BQV0J03 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $12,449.49 | 6,803 | BN4JN37 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,359.14 | 3,974 | BZ8FPH3 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,152.28 | 3,774 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,717.42 | 4,097 | BZC0D70 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,717.40 | 3,972 | BKX9NQ0 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,670.40 | 1,560 | BP81RK8 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,667.54 | 1,157 | BKC9SX3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,647.00 | 6,084 | BRK0149 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,580.52 | 2,383 | BMF7DT9 |
| 0.01% | CDXS | CODEXIS INC | -- | $10,476.60 | 3,676 | B5LL2C2 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,051.80 | 4,569 | BKRRKY7 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,737.73 | 1,263 | BP2NYN2 |
| 0.01% | OABI | OMNIAB INC | -- | $9,724.28 | 5,858 | BN13S71 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,720.00 | 2,400 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,283.92 | 2,298 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,062.04 | 1,884 | BKDQKM6 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $8,823.00 | 8,823 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,345.57 | 2,179 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,328.42 | 7,857 | BMYTJP4 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,377.82 | 3,803 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,295.17 | 1,523 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,211.10 | 7,954 | BNR5QT9 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $6,945.90 | 2,535 | BLBR8D5 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,930.82 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,191.00 | 3,020 | BPTK6Z2 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,928.00 | 2,800 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,819.84 | 886 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,834.00 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,080.01 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 39.32% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,412,283 | -- | 5,132 | -- |
| 27.00% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,883,259 | -- | 3,524 | -- |
| 25.85% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,994,358 | -- | 3,374 | -- |
| 20.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,638,740 | -- | 2,639 | -- |
| 16.86% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,043,148 | -- | 2,201 | -- |
| 4.85% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,751,164 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,571,953.45 | 26,571,953 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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