BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,050,253
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 3/27/2026- NAV
- NAV Change
- Market Price $73.81
- Market Price Change $-4.61
- Trading Volume (M) 11,750
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,050,253
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 3/27/2026- NAV
- NAV Change
- Market Price $73.81
- Market Price Change $-4.61
- Trading Volume (M) 11,750
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/27/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.68% | GILD | GILEAD SCIENCES INC | -- | $4,148,996.25 | 30,905 | 2369174 |
| 5.66% | AMGN | AMGEN INC | -- | $4,136,412.20 | 11,860 | 2023607 |
| 5.49% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,012,393.55 | 9,265 | 2931034 |
| 4.69% | REGN | REGENERON PHARMACEUTICALS | -- | $3,428,138.37 | 4,647 | 2730190 |
| 2.58% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,882,579.52 | 5,932 | B00FWN1 |
| 1.92% | INSM | INSMED INC | -- | $1,400,982.60 | 9,642 | 2614487 |
| 1.65% | BIIB | BIOGEN INC | -- | $1,206,725.76 | 6,564 | 2455965 |
| 1.40% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,024,746.80 | 1,960 | 2430412 |
| 1.22% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $888,297.75 | 19,165 | BMVP7Y0 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $877,386.60 | 1,269 | BDVLM39 |
| 1.20% | MRNA | MODERNA INC | -- | $875,576.52 | 17,667 | BGSXTS3 |
| 1.16% | ROIV | ROIVANT SCIENCES LTD | -- | $849,090.84 | 32,017 | BMW4NZ9 |
| 1.12% | RVMD | REVOLUTION MEDICINES INC | -- | $820,101.15 | 8,865 | BL71K91 |
| 1.10% | ILMN | ILLUMINA INC | -- | $804,980.47 | 6,841 | 2613990 |
| 1.10% | INCY | INCYTE CORP | -- | $803,850.60 | 8,902 | 2471950 |
| 0.92% | VTRS | VIATRIS INC | -- | $672,166.35 | 51,507 | BMWS3X9 |
| 0.83% | BBIO | BRIDGEBIO PHARMA INC | -- | $604,508.10 | 8,673 | BK1KWG8 |
| 0.82% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $597,480.30 | 2,754 | BV9G6B8 |
| 0.79% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $576,156.80 | 4,490 | 2623911 |
| 0.79% | SMMT | SUMMIT THERAPEUTICS INC | -- | $575,093.88 | 34,686 | BMTVQS7 |
| 0.78% | MEDP | MEDPACE HOLDINGS INC | -- | $572,572.80 | 1,269 | BDCBC61 |
| 0.73% | IONS | IONIS PHARMACEUTICALS INC | -- | $533,188.50 | 7,390 | BDJ0LS6 |
| 0.72% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $524,468.36 | 1,027 | BD59BS7 |
| 0.70% | SNY | SANOFI-ADR | -- | $512,194.22 | 10,949 | 2964557 |
| 0.69% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $503,128.26 | 2,754 | B4Q5ZN4 |
| 0.68% | GH | GUARDANT HEALTH INC | -- | $496,406.87 | 5,867 | BFXC911 |
| 0.66% | EXEL | EXELIXIS INC | -- | $482,454.01 | 11,617 | 2576941 |
| 0.64% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $465,820.56 | 8,604 | 2437071 |
| 0.60% | BNTX | BIONTECH SE-ADR | -- | $436,625.28 | 5,096 | BK6H543 |
| 0.55% | ONC | BEONE MEDICINES LTD-ADR | -- | $404,732.90 | 1,430 | BYYWPW6 |
| 0.50% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $361,991.70 | 6,265 | BYQBFJ8 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $361,174.50 | 1,245 | BQ721R4 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $357,885.15 | 2,289 | BYZR4X4 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $344,312.50 | 5,509 | BBBSBJ5 |
| 0.47% | PCVX | VAXCYTE INC | -- | $342,244.08 | 6,438 | BKPVGH6 |
| 0.46% | IBRX | IMMUNITYBIO INC | -- | $339,413.58 | 45,991 | BNSP0B8 |
| 0.45% | TEM | TEMPUS AI INC-CL A | -- | $331,200.02 | 7,771 | BSLSJJ0 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $325,406.40 | 5,280 | 2975098 |
| 0.44% | KRYS | KRYSTAL BIOTECH INC | -- | $321,215.51 | 1,309 | BD6JX35 |
| 0.43% | NUVL | NUVALENT INC-A | -- | $316,464.84 | 3,274 | BMVBZD3 |
| 0.41% | ACLX | ARCELLX INC | -- | $299,715.12 | 2,616 | BPCJ1Q2 |
| 0.39% | KYMR | KYMERA THERAPEUTICS INC | -- | $285,362.16 | 3,651 | BMPRZV5 |
| 0.39% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $282,559.35 | 2,855 | BDCBCD8 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $281,587.56 | 2,748 | BLC89B2 |
| 0.36% | COGT | COGENT BIOSCIENCES INC | -- | $262,122.10 | 7,261 | BLR6XK8 |
| 0.34% | TERN | TERNS PHARMACEUTICALS INC | -- | $251,740.44 | 4,757 | BMDJ0C9 |
| 0.34% | PTCT | PTC THERAPEUTICS INC | -- | $244,879.39 | 3,703 | B17VCN9 |
| 0.33% | CGON | CG ONCOLOGY INC | -- | $244,134.36 | 3,778 | BRBCSP4 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $238,699.56 | 2,699 | BJDX8Y8 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $231,630.10 | 3,055 | BF2YWG4 |
| 0.30% | ALKS | ALKERMES PLC | -- | $219,102.45 | 7,455 | B3P6D26 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $218,361.88 | 9,106 | BJRFSB7 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $213,942.90 | 12,622 | BT18HP9 |
| 0.28% | ERAS | ERASCA INC | -- | $207,334.50 | 13,850 | BNLYBF3 |
| 0.28% | XENE | XENON PHARMACEUTICALS INC | -- | $202,774.56 | 3,722 | BRJ3GY4 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $196,404.75 | 4,293 | BDHF4K6 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $194,426.40 | 4,564 | BFZQ0L8 |
| 0.26% | APGE | APOGEE THERAPEUTICS INC | -- | $190,814.64 | 2,452 | BM9HHL5 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $174,172.68 | 891 | 2501578 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $166,800.60 | 14,076 | BFNF1D6 |
| 0.23% | SYRE | SPYRE THERAPEUTICS INC | -- | $166,200.03 | 3,513 | BQBBDY8 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $162,058.18 | 5,594 | BTZRLN8 |
| 0.22% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $160,031.20 | 3,485 | BQS9486 |
| 0.22% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $158,239.50 | 7,626 | 2713317 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $157,710.28 | 4,684 | BDD19F8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $154,157.16 | 5,142 | BP8JSP4 |
| 0.21% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $153,573.70 | 5,351 | BLB0YQ9 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $147,970.32 | 4,798 | BKY5JZ8 |
| 0.19% | ALMS | ALUMIS INC | -- | $140,244.00 | 5,655 | BPLQG36 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $128,845.20 | 7,095 | BD2B4V0 |
| 0.17% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $127,018.80 | 2,565 | B72ZBG4 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $126,236.10 | 7,365 | BN15WD1 |
| 0.17% | TARS | TARSUS PHARMACEUTICALS INC | -- | $126,073.75 | 1,903 | BMH5RL1 |
| 0.17% | VERA | VERA THERAPEUTICS INC | -- | $124,041.12 | 3,192 | BL55460 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $122,101.26 | 2,742 | BGKG6G7 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $119,677.34 | 3,929 | BK0VHF6 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,643.68 | 5,544 | BKX9VD3 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $116,041.50 | 6,025 | BP2P6L0 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $112,460.75 | 4,127 | BLFGJD5 |
| 0.15% | VCYT | VERACYTE INC | -- | $106,685.55 | 3,555 | BFTWZY0 |
| 0.14% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $104,682.60 | 11,220 | 2100362 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $103,132.48 | 2,656 | BMFD115 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $102,573.63 | 1,707 | BMGJZJ8 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $102,542.72 | 5,264 | BKS3RS7 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $101,119.83 | 4,557 | BK6L288 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $101,010.00 | 2,730 | BFXC933 |
| 0.14% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $98,935.61 | 4,621 | BLB0YH0 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $98,549.50 | 10,654 | B9NSBM2 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $97,034.46 | 5,718 | BYTQ6X1 |
| 0.13% | ORKA | ORUKA THERAPEUTICS INC | -- | $96,299.20 | 2,165 | BKVF0J2 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $93,924.75 | 2,053 | BRXB0C0 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $93,619.36 | 4,688 | B8DPDT7 |
| 0.13% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $92,668.05 | 3,945 | BN7Q7R7 |
| 0.12% | TYRA | TYRA BIOSCIENCES INC | -- | $86,624.23 | 2,387 | BMVNDH9 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $85,480.08 | 6,888 | BJ5FZ74 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $84,877.96 | 5,948 | BFWLC09 |
| 0.12% | GRAL | GRAIL INC | -- | $84,518.07 | 1,743 | BSLSSX7 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $83,931.75 | 2,555 | BJQ05Z6 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $83,827.20 | 3,540 | BP9N0G0 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $83,779.74 | 4,323 | BJ62Z18 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $80,954.64 | 3,348 | BPCQZY9 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $79,744.80 | 4,460 | BV2DHY6 |
| 0.11% | PHVS | PHARVARIS NV | -- | $78,385.10 | 2,866 | BMZ2X38 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $77,136.03 | 2,621 | BCBVTX1 |
| 0.11% | RLAY | RELAY THERAPEUTICS INC | -- | $76,752.00 | 7,995 | BN2R582 |
| 0.10% | INVA | INNOVIVA INC | -- | $75,072.58 | 3,313 | BDDXF67 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $74,335.78 | 2,879 | BBC9WC7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $73,529.45 | 9,739 | BNZB1X8 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $73,038.46 | 1,003 | BCDWBX6 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $72,211.52 | 1,997 | BQKXDX4 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $71,176.00 | 1,240 | BDRW1L7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,685.52 | 2,588 | BKSGZN7 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $68,646.06 | 23,349 | BM9FJ13 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $67,896.00 | 4,600 | BMVLGP2 |
| 0.09% | VCEL | VERICEL CORP | -- | $66,631.14 | 2,271 | BSBMN89 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $66,571.15 | 4,913 | BPCK358 |
| 0.09% | MAZE | MAZE THERAPEUTICS INC | -- | $65,408.14 | 2,153 | BSRK699 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,363.08 | 5,284 | BYZM6C2 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $64,988.88 | 5,736 | BJH9ZN0 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $64,682.28 | 18,428 | BF0DMK7 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $63,436.80 | 3,776 | BMX9K07 |
| 0.08% | NVAX | NOVAVAX INC | -- | $61,583.60 | 7,288 | BJDQXG4 |
| 0.08% | ARDX | ARDELYX INC | -- | $60,115.60 | 10,970 | BN89V40 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $59,354.88 | 2,132 | BR3T9B6 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $59,060.40 | 7,031 | BK4PZ38 |
| 0.08% | PGEN | PRECIGEN INC | -- | $58,088.76 | 15,828 | BKM5C84 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $57,731.84 | 1,961 | BLCD809 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $57,256.50 | 2,009 | BQXJKH2 |
| 0.08% | HROW | HARROW INC | -- | $56,090.14 | 1,658 | BHNDW86 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $55,837.30 | 5,090 | BYSS4X4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $54,430.80 | 16,248 | BWJDYK1 |
| 0.07% | ORIC | ORIC PHARMACEUTICALS INC | -- | $54,149.40 | 4,490 | BKVDFF7 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $53,599.67 | 8,421 | BYZG9R0 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $52,461.18 | 3,411 | BP7KZP7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $52,060.58 | 2,834 | BQB42F1 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,752.94 | 3,694 | BYP80F1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $49,869.71 | 12,253 | BNC1BX1 |
| 0.07% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,731.24 | 923 | BL95N25 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $49,006.95 | 3,585 | BMZ4LN0 |
| 0.07% | SEPN | SEPTERNA INC | -- | $47,811.61 | 2,003 | BQNKXX2 |
| 0.06% | SVRA | SAVARA INC | -- | $46,789.42 | 9,103 | BYXGN81 |
| 0.06% | EYPT | EYEPOINT INC | -- | $46,300.00 | 3,704 | BMGS7L1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $46,097.24 | 1,421 | BX7RSN3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $45,953.36 | 14,776 | BPNTJ34 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $44,347.74 | 13,562 | BL53SR3 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $44,341.35 | 2,435 | BQB42H3 |
| 0.06% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $43,705.13 | 2,261 | BD06CS0 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,412.80 | 1,810 | B3X26D8 |
| 0.06% | QURE | UNIQURE NV | -- | $41,163.99 | 2,787 | BJFSR88 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $40,872.93 | 5,457 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,078.80 | 7,422 | BLR7H87 |
| 0.05% | GERN | GERON CORP | -- | $39,978.40 | 28,556 | 2370381 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $39,581.21 | 1,847 | BMGTLY5 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $38,571.29 | 2,029 | BNFWZS4 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $38,011.89 | 651 | BNSP8K3 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $37,939.81 | 4,183 | BRXYZ57 |
| 0.05% | XNCR | XENCOR INC | -- | $37,469.02 | 3,281 | BGCYWN8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,283.92 | 3,524 | BJLKVS6 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,911.16 | 8,604 | BZ0QMB7 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $36,491.25 | 2,775 | BP6C0S2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $35,936.81 | 2,093 | BZ7PJQ1 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,875.96 | 2,722 | BMFX8Y7 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,693.61 | 4,423 | BMCR7V2 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $34,257.08 | 7,579 | BYWVTY5 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,186.36 | 2,267 | BMNDK09 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,962.55 | 2,643 | BM90J52 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,631.12 | 2,342 | BQS7491 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $33,007.32 | 11,916 | BMFJJ97 |
| 0.04% | ANNX | ANNEXON INC | -- | $32,375.00 | 6,475 | BMVV9R5 |
| 0.04% | MNKD | MANNKIND CORP | -- | $31,425.24 | 13,783 | BF081J4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,395.60 | 1,944 | BT9K6D8 |
| 0.04% | OMER | OMEROS CORP | -- | $31,329.48 | 3,171 | B4NB858 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $31,294.90 | 1,330 | BKLCWZ3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $30,124.08 | 3,892 | BYZD465 |
| 0.04% | PSNL | PERSONALIS INC | -- | $29,677.54 | 4,681 | BJQ0608 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,301.56 | 10,694 | BBNBTD2 |
| 0.04% | ARVN | ARVINAS INC | -- | $28,906.20 | 2,862 | BDZ30Q0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $27,864.76 | 1,199 | BGL0JK3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $27,594.00 | 1,533 | BD9GVY0 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,432.00 | 3,600 | BFYQFJ2 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $27,293.50 | 8,075 | BPBJFM7 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $26,903.84 | 1,858 | BRJJYT3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,830.44 | 2,548 | BMFK3H6 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $26,670.68 | 3,694 | BDDVW37 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $24,785.46 | 3,486 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $24,654.00 | 840 | BPBPCG8 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,646.04 | 3,524 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,055.72 | 2,517 | BLFBZ32 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,719.78 | 10,053 | BFZNYB7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $22,661.40 | 4,220 | BMC3HS7 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,439.34 | 4,857 | BMXNGZ6 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,298.08 | 2,408 | B91XRN2 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,282.92 | 7,282 | B3MZ6K5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,941.16 | 5,458 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,291.06 | 2,282 | BKLXFX5 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,035.15 | 2,581 | B2Q9833 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,983.53 | 813 | BQD3J33 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,964.06 | 2,418 | BRCFFK6 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,436.09 | 1,713 | BP81RK8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $20,048.67 | 2,979 | BJDX8Z9 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $19,936.80 | 2,556 | BSMLR16 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,209.52 | 664 | B292NQ7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $18,990.40 | 5,395 | BYV2W40 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $18,730.14 | 6,549 | BMCWKZ2 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,706.17 | 951 | BTNMG41 |
| 0.03% | ABSI | ABSCI CORP | -- | $18,698.28 | 6,726 | BN94K69 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,339.14 | 2,654 | B12W3P6 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,314.66 | 4,858 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,169.08 | 1,362 | BPRBTY7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,894.40 | 3,495 | BLN9Z50 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,826.90 | 3,265 | BQ6C357 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,813.07 | 2,841 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $17,568.64 | 2,264 | BZ0G875 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $17,416.75 | 7,475 | BN4JN37 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,021.34 | 13,509 | B4N8MH9 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,982.52 | 12,396 | BM8NHS1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,981.20 | 3,204 | 2107437 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,918.04 | 5,602 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,821.82 | 1,299 | B9L5200 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,728.70 | 3,270 | BP0TQC5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,461.43 | 1,363 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,235.20 | 2,870 | BMVBZF5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,082.20 | 692 | BS2F741 |
| 0.02% | PEPG | PEPGEN INC | -- | $13,903.52 | 3,076 | BMTX3D7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,838.08 | 2,276 | B7F2TY6 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,753.34 | 5,021 | BKRRKY7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,152.70 | 4,501 | BZC0D70 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,790.00 | 2,620 | BMF7DT9 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,751.60 | 1,399 | BQV0J03 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,691.72 | 4,146 | BYTYP72 |
| 0.02% | EOLS | EVOLUS INC | -- | $11,624.99 | 2,899 | BDRJH21 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,540.08 | 4,306 | BK5MWR1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,899.81 | 6,687 | BRK0149 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,857.33 | 8,973 | BFMLGR4 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,756.50 | 2,525 | BPRB2N7 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $10,517.24 | 4,364 | BKX9NQ0 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,442.52 | 2,637 | BY7RB53 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,353.00 | 2,100 | BL5B6Z1 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,736.18 | 4,366 | BZ8FPH3 |
| 0.01% | OABI | OMNIAB INC | -- | $9,722.89 | 6,439 | BN13S71 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,934.63 | 2,073 | BKDQKM6 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,591.96 | 1,271 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,442.18 | 4,181 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $6,777.54 | 1,386 | BP2NYN2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,679.76 | 8,742 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,487.74 | 2,394 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,448.81 | 9,696 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,440.80 | 3,320 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,384.78 | 4,041 | B5LL2C2 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,130.50 | 1,675 | 2517058 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,832.45 | 8,633 | BMYTJP4 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,174.47 | 2,549 | BKTV702 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,649.66 | 2,786 | BLBR8D5 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,587.66 | 10,354 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,536.65 | 4,363 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,454.15 | 973 | BTXQTX3 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $24.43 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 32.54% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 23,768,080 | -- | 4,283 | -- |
| 28.12% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,543,879 | -- | 3,702 | -- |
| 27.51% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 20,094,377 | -- | 3,621 | -- |
| 20.05% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 14,644,867 | -- | 2,639 | -- |
| 15.12% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,043,306 | -- | 1,990 | -- |
| 4.81% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,512,770 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $20,169,320.17 | 20,169,320 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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