BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,824,153
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/18/2026- NAV $77.05
- NAV Change $-3.26
- Market Price $77.03
- Market Price Change $-3.21
- Trading Volume (M) 14,557
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,824,153
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/18/2026- NAV $77.05
- NAV Change $-3.26
- Market Price $77.03
- Market Price Change $-3.21
- Trading Volume (M) 14,557
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/18/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.94% | GILD | GILEAD SCIENCES INC | -- | $5,403,636.05 | 38,245 | 2369174 |
| 6.44% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,011,745.82 | 11,098 | 2931034 |
| 6.29% | AMGN | AMGEN INC | -- | $4,897,170.84 | 13,933 | 2023607 |
| 4.37% | REGN | REGENERON PHARMACEUTICALS | -- | $3,401,372.52 | 4,571 | 2730190 |
| 2.36% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,840,320.80 | 5,846 | B00FWN1 |
| 1.73% | INSM | INSMED INC | -- | $1,346,659.90 | 9,437 | 2614487 |
| 1.52% | BIIB | BIOGEN INC | -- | $1,183,556.52 | 6,492 | 2455965 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,009,786.40 | 1,904 | 2430412 |
| 1.16% | MRNA | MODERNA INC | -- | $905,943.60 | 17,289 | BGSXTS3 |
| 1.13% | ARGX | ARGENX SE - ADR | -- | $881,298.99 | 1,287 | BDVLM39 |
| 1.11% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $865,888.90 | 18,910 | BMVP7Y0 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $855,656.20 | 30,779 | BMW4NZ9 |
| 1.08% | RVMD | REVOLUTION MEDICINES INC | -- | $839,331.05 | 8,555 | BL71K91 |
| 1.07% | ILMN | ILLUMINA INC | -- | $831,264.95 | 6,761 | 2613990 |
| 1.03% | INCY | INCYTE CORP | -- | $801,288.88 | 8,687 | 2471950 |
| 0.90% | VTRS | VIATRIS INC | -- | $700,355.28 | 50,972 | BMWS3X9 |
| 0.79% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $618,100.38 | 2,718 | BV9G6B8 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $597,983.36 | 8,528 | BK1KWG8 |
| 0.74% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $576,692.52 | 4,412 | 2623911 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $567,135.60 | 1,247 | BDCBC61 |
| 0.66% | SMMT | SUMMIT THERAPEUTICS INC | -- | $513,973.20 | 32,947 | BMTVQS7 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $513,658.89 | 7,167 | BDJ0LS6 |
| 0.66% | SNY | SANOFI-ADR | -- | $511,931.52 | 11,712 | 2964557 |
| 0.64% | GH | GUARDANT HEALTH INC | -- | $499,620.75 | 5,725 | BFXC911 |
| 0.63% | EXEL | EXELIXIS INC | -- | $489,549.90 | 11,865 | 2576941 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $485,230.05 | 2,689 | B4Q5ZN4 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $471,265.86 | 8,502 | 2437071 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $443,326.00 | 1,003 | BD59BS7 |
| 0.52% | BNTX | BIONTECH SE-ADR | -- | $402,660.00 | 4,474 | BK6H543 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $393,512.26 | 1,394 | BYYWPW6 |
| 0.48% | IBRX | IMMUNITYBIO INC | -- | $373,138.96 | 43,591 | BNSP0B8 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $372,429.81 | 7,649 | BSLSJJ0 |
| 0.45% | AXSM | AXSOME THERAPEUTICS INC | -- | $352,207.97 | 2,231 | BYZR4X4 |
| 0.44% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $340,827.10 | 6,010 | BYQBFJ8 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $336,572.28 | 5,412 | BBBSBJ5 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $331,298.25 | 5,205 | 2975098 |
| 0.42% | ABVX | ABIVAX SA-ADR | -- | $323,861.88 | 2,612 | BLC89B2 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $321,564.06 | 1,282 | BD6JX35 |
| 0.41% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $319,690.53 | 1,107 | BQ721R4 |
| 0.40% | PCVX | VAXCYTE INC | -- | $314,389.76 | 5,792 | BKPVGH6 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $311,483.71 | 3,197 | BMVBZD3 |
| 0.38% | ACLX | ARCELLX INC | -- | $293,031.09 | 2,559 | BPCJ1Q2 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $268,648.03 | 2,767 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $253,544.58 | 2,953 | BF2YWG4 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $251,981.76 | 3,184 | BMPRZV5 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $238,118.00 | 3,554 | B17VCN9 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $233,509.78 | 6,794 | BLR6XK8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $230,616.42 | 12,486 | BT18HP9 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $230,022.05 | 3,569 | BRBCSP4 |
| 0.27% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $208,434.84 | 2,274 | BJDX8Y8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $201,108.73 | 4,217 | BDHF4K6 |
| 0.26% | ALKS | ALKERMES PLC | -- | $198,723.20 | 7,306 | B3P6D26 |
| 0.25% | FOLD | AMICUS THERAPEUTICS INC | -- | $196,236.72 | 13,656 | B19FQ48 |
| 0.24% | TERN | TERNS PHARMACEUTICALS INC | -- | $190,451.08 | 3,986 | BMDJ0C9 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $188,394.47 | 3,421 | BRJ3GY4 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $183,088.80 | 7,758 | BJRFSB7 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $182,282.40 | 870 | 2501578 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $179,651.85 | 4,515 | BFZQ0L8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $172,382.07 | 13,913 | BFNF1D6 |
| 0.22% | ERAS | ERASCA INC | -- | $169,492.50 | 12,555 | BNLYBF3 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $168,617.19 | 5,523 | BTZRLN8 |
| 0.21% | APGE | APOGEE THERAPEUTICS INC | -- | $162,050.79 | 2,427 | BM9HHL5 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $156,640.58 | 10,534 | B9NSBM2 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $153,438.73 | 2,957 | BQS9486 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $152,156.16 | 7,488 | 2713317 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $151,373.95 | 4,199 | BDD19F8 |
| 0.19% | SYRE | SPYRE THERAPEUTICS INC | -- | $147,824.98 | 3,433 | BQBBDY8 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $147,700.48 | 5,017 | BP8JSP4 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $139,097.65 | 4,685 | BKY5JZ8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $130,189.40 | 6,490 | BD2B4V0 |
| 0.17% | IDYA | IDEAYA BIOSCIENCES INC | -- | $129,242.80 | 3,880 | BK0VHF6 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $128,291.20 | 1,880 | BMH5RL1 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $125,048.73 | 2,537 | B72ZBG4 |
| 0.16% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $122,562.99 | 4,269 | BLB0YQ9 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $120,585.28 | 5,422 | BKX9VD3 |
| 0.15% | TWST | TWIST BIOSCIENCE CORP | -- | $120,308.76 | 2,706 | BGKG6G7 |
| 0.15% | VCYT | VERACYTE INC | -- | $116,380.16 | 3,497 | BFTWZY0 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $115,629.38 | 6,322 | BN15WD1 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $113,686.80 | 4,490 | BK6L288 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $111,351.48 | 5,961 | BP2P6L0 |
| 0.14% | ALMS | ALUMIS INC | -- | $109,382.26 | 4,303 | BPLQG36 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $108,330.64 | 2,827 | BL55460 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $106,761.60 | 3,960 | BLFGJD5 |
| 0.13% | MAZE | MAZE THERAPEUTICS INC | -- | $103,192.63 | 2,129 | BSRK699 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $100,112.44 | 5,596 | BYTQ6X1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $98,873.72 | 1,672 | BMGJZJ8 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $96,811.33 | 4,543 | BLB0YH0 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $90,957.90 | 3,846 | BN7Q7R7 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $90,254.85 | 1,999 | BRXB0C0 |
| 0.12% | TYRA | TYRA BIOSCIENCES INC | -- | $89,874.10 | 2,362 | BMVNDH9 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $89,706.40 | 6,755 | BJ5FZ74 |
| 0.11% | TXG | 10X GENOMICS INC-CLASS A | -- | $89,421.90 | 5,154 | BKS3RS7 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $88,083.80 | 7,402 | BYZG9R0 |
| 0.11% | ORKA | ORUKA THERAPEUTICS INC | -- | $87,434.40 | 2,143 | BKVF0J2 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $87,343.74 | 4,269 | BJ62Z18 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $85,343.72 | 9,317 | 2100362 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $83,673.90 | 3,501 | BP9N0G0 |
| 0.11% | GRAL | GRAIL INC | -- | $83,507.25 | 1,725 | BSLSSX7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $82,170.88 | 5,836 | BFWLC09 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $80,052.21 | 9,429 | BNZB1X8 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $79,570.92 | 4,637 | B8DPDT7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $79,217.28 | 1,224 | BDRW1L7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $78,387.54 | 2,527 | BJQ05Z6 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $77,666.40 | 3,312 | BPCQZY9 |
| 0.10% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $76,892.76 | 4,359 | BV2DHY6 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $76,163.10 | 7,670 | BN2R582 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $75,549.92 | 22,756 | BM9FJ13 |
| 0.10% | PHVS | PHARVARIS NV | -- | $74,191.95 | 2,835 | BMZ2X38 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $73,799.15 | 995 | BCDWBX6 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $72,603.53 | 2,581 | BCBVTX1 |
| 0.09% | INVA | INNOVIVA INC | -- | $72,434.01 | 3,309 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,319.70 | 2,239 | BSBMN89 |
| 0.09% | NVAX | NOVAVAX INC | -- | $71,991.92 | 7,192 | BJDQXG4 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $71,585.75 | 2,627 | BMFD115 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $70,989.65 | 2,549 | BKSGZN7 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $67,905.60 | 1,974 | BQKXDX4 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $67,850.46 | 3,726 | BMX9K07 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $67,714.46 | 5,126 | BYZM6C2 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $67,499.25 | 4,485 | BMVLGP2 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $67,033.19 | 4,861 | BPCK358 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $66,899.80 | 2,588 | BBC9WC7 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,231.36 | 17,568 | BF0DMK7 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $60,665.75 | 5,675 | BJH9ZN0 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $59,757.30 | 4,955 | BYSS4X4 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,673.60 | 10,752 | BN89V40 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $58,007.24 | 1,931 | BLCD809 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $57,383.24 | 6,157 | BK4PZ38 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $57,223.44 | 16,074 | BWJDYK1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $56,998.20 | 1,986 | BQXJKH2 |
| 0.07% | HROW | HARROW INC | -- | $56,478.24 | 1,638 | BHNDW86 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $55,819.84 | 2,108 | BR3T9B6 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $54,719.28 | 2,376 | BQB42H3 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $53,947.35 | 12,123 | BNC1BX1 |
| 0.07% | ALVO | ALVOTECH SA | -- | $52,645.20 | 13,854 | BPNTJ34 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $51,843.84 | 2,348 | BFXC933 |
| 0.07% | PGEN | PRECIGEN INC | -- | $51,208.20 | 15,660 | BKM5C84 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $50,715.33 | 3,482 | BMZ4LN0 |
| 0.06% | EYPT | EYEPOINT INC | -- | $49,963.32 | 3,663 | BMGS7L1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,720.00 | 1,400 | BX7RSN3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $47,737.80 | 1,980 | BQNKXX2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $47,372.61 | 907 | BL95N25 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $46,817.46 | 4,311 | BKVDFF7 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,625.92 | 13,246 | BL53SR3 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $46,534.40 | 3,305 | BYP80F1 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $45,404.56 | 2,881 | BP7KZP7 |
| 0.06% | SVRA | SAVARA INC | -- | $45,385.20 | 9,005 | BYXGN81 |
| 0.06% | BCAX | BICARA THERAPEUTICS INC | -- | $44,644.25 | 2,425 | BQB42F1 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $44,305.05 | 645 | BNSP8K3 |
| 0.06% | GERN | GERON CORP | -- | $43,785.95 | 28,249 | 2370381 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $42,490.13 | 5,399 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,882.04 | 1,902 | B3X26D8 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $41,696.68 | 1,828 | BMGTLY5 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $41,214.88 | 2,744 | BP6C0S2 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,644.66 | 4,089 | BRXYZ57 |
| 0.05% | QURE | UNIQURE NV | -- | $40,610.61 | 2,757 | BJFSR88 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $39,877.92 | 7,344 | BLR7H87 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $38,665.00 | 2,035 | BNFWZS4 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $38,290.56 | 2,072 | BZ7PJQ1 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $36,909.18 | 2,663 | BMFX8Y7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,902.70 | 11,790 | BMFJJ97 |
| 0.05% | XNCR | XENCOR INC | -- | $36,624.40 | 3,160 | BGCYWN8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,312.50 | 4,375 | BMCR7V2 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,176.00 | 8,512 | BZ0QMB7 |
| 0.05% | MNKD | MANNKIND CORP | -- | $35,467.29 | 13,589 | BF081J4 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,709.68 | 6,404 | BMVV9R5 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $34,666.62 | 2,238 | BD06CS0 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $34,491.12 | 3,147 | BJLKVS6 |
| 0.04% | OMER | OMEROS CORP | -- | $34,372.05 | 3,139 | B4NB858 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,321.82 | 2,614 | BM90J52 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,068.97 | 1,291 | BKLCWZ3 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,995.60 | 7,499 | BYWVTY5 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,632.39 | 1,733 | BD9GVY0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,301.50 | 3,850 | BYZD465 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,761.73 | 2,171 | BQS7491 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,034.52 | 2,244 | BMNDK09 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,949.38 | 2,842 | BDZ30Q0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,724.32 | 1,587 | BT9K6D8 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $28,194.11 | 7,987 | BPBJFM7 |
| 0.04% | PSNL | PERSONALIS INC | -- | $27,352.80 | 3,930 | BJQ0608 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $26,620.20 | 828 | BPBPCG8 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $26,500.40 | 10,579 | BBNBTD2 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $26,458.23 | 3,561 | BFYQFJ2 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,976.60 | 2,522 | BMFK3H6 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $24,549.76 | 3,448 | BQHN6C7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $24,525.48 | 4,171 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,798.60 | 2,492 | BLFBZ32 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $23,470.72 | 3,472 | BDDVW37 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,824.00 | 7,200 | B3MZ6K5 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $22,595.76 | 1,188 | BGL0JK3 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $22,384.40 | 2,615 | B12W3P6 |
| 0.03% | CRMD | CORMEDIX INC | -- | $22,218.56 | 3,488 | BJ0LT31 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,930.27 | 2,553 | B2Q9833 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,703.98 | 5,399 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,631.12 | 2,527 | BKLXFX5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,381.75 | 9,945 | BFZNYB7 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $21,380.01 | 4,783 | BDFKQ07 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,709.35 | 2,390 | BRCFFK6 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $20,620.97 | 641 | B292NQ7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,469.97 | 2,383 | B91XRN2 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $20,430.87 | 3,457 | BLN9Z50 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,402.88 | 802 | BQD3J33 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,112.84 | 1,693 | BP81RK8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $19,571.85 | 6,417 | BMCWKZ2 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $19,520.16 | 7,394 | BN4JN37 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,036.16 | 6,656 | BN94K69 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,796.22 | 937 | BTNMG41 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,582.90 | 3,229 | BQ6C357 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,555.48 | 2,241 | BZ0G875 |
| 0.02% | IVVD | INVIVYD INC | -- | $18,520.15 | 12,265 | BM8NHS1 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,483.22 | 2,809 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,771.46 | 13,362 | B4N8MH9 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $17,553.36 | 4,796 | BYV2W40 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,844.04 | 3,954 | BYTYP72 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,566.48 | 2,394 | BJDX8Z9 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,559.06 | 1,939 | BSMLR16 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $16,288.40 | 3,788 | BMXNGZ6 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $16,232.20 | 1,385 | BQV0J03 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,230.60 | 1,278 | B9L5200 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,793.56 | 4,618 | BFY7DC4 |
| 0.02% | PEPG | PEPGEN INC | -- | $15,580.16 | 3,043 | BMTX3D7 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $15,401.34 | 3,169 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,771.55 | 1,349 | BM7V485 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,862.10 | 2,870 | BDRJH21 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,783.77 | 2,079 | BL5B6Z1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,731.96 | 4,444 | BZC0D70 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,661.24 | 2,858 | BMVBZF5 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,380.00 | 2,230 | B7F2TY6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,357.50 | 685 | BS2F741 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,972.00 | 4,600 | BKRRKY7 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,873.10 | 8,878 | BFMLGR4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,649.23 | 4,259 | BK5MWR1 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,488.84 | 1,022 | BPRBTY7 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $12,247.20 | 2,430 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,214.64 | 2,503 | BMF7DT9 |
| 0.01% | OABI | OMNIAB INC | -- | $11,595.22 | 6,371 | BN13S71 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,537.41 | 4,289 | BKX9NQ0 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,270.49 | 2,499 | BPRB2N7 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,156.70 | 4,322 | BZ8FPH3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,802.32 | 2,607 | BY7RB53 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $9,685.00 | 745 | BRJJYT3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,616.20 | 2,046 | BKDQKM6 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,784.22 | 8,287 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,453.00 | 5,350 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,239.90 | 1,258 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,899.76 | 4,136 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,637.17 | 8,655 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,880.70 | 1,658 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $6,667.92 | 1,372 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,562.13 | 2,369 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,059.36 | 7,367 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,021.56 | 3,364 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,875.59 | 3,997 | B5LL2C2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,474.91 | 2,523 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,138.42 | 4,318 | BNNXX18 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,699.44 | 963 | BTXQTX3 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,446.49 | 10,243 | BJ0CK86 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,215.15 | 2,755 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $21.79 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 32.55% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,329,440 | -- | 4,475 | -- |
| 31.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,242,679 | -- | 4,283 | -- |
| 26.93% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,954,097 | -- | 3,702 | -- |
| 19.19% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 14,937,294 | -- | 2,639 | -- |
| 14.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,263,818 | -- | 1,990 | -- |
| 4.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,582,913 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $22,372,662.27 | 22,372,662 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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