BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $67,884,201
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/10/2026- NAV
- NAV Change
- Market Price $78.07
- Market Price Change $-3.02
- Trading Volume (M) 5,895
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $67,884,201
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/10/2026- NAV
- NAV Change
- Market Price $78.07
- Market Price Change $-3.02
- Trading Volume (M) 5,895
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/10/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.91% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,336,231.47 | 7,657 | 2931034 |
| 4.88% | AMGN | AMGEN INC | -- | $3,310,767.19 | 9,803 | 2023607 |
| 4.57% | GILD | GILEAD SCIENCES INC | -- | $3,102,842.16 | 25,542 | 2369174 |
| 3.40% | REGN | REGENERON PHARMACEUTICALS | -- | $2,310,336.00 | 3,840 | 2730190 |
| 2.10% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,428,142.88 | 4,904 | B00FWN1 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,056,335.94 | 7,326 | BL71K91 |
| 1.55% | BIIB | BIOGEN INC | -- | $1,053,752.00 | 5,425 | 2455965 |
| 1.35% | ILMN | ILLUMINA INC | -- | $918,442.91 | 5,653 | 2613990 |
| 1.33% | ARGX | ARGENX SE - ADR | -- | $905,289.00 | 1,050 | BDVLM39 |
| 1.30% | UTHR | UNITED THERAPEUTICS CORP | -- | $881,442.00 | 1,620 | 2430412 |
| 1.27% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $863,433.24 | 15,837 | BMVP7Y0 |
| 1.14% | INCY | INCYTE CORP | -- | $775,565.01 | 7,359 | 2471950 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $751,728.60 | 26,460 | BMW4NZ9 |
| 1.08% | INSM | INSMED INC | -- | $732,099.84 | 7,968 | 2614487 |
| 0.99% | MRNA | MODERNA INC | -- | $671,454.00 | 14,600 | BGSXTS3 |
| 0.99% | VTRS | VIATRIS INC | -- | $671,250.05 | 42,565 | BMWS3X9 |
| 0.93% | GH | GUARDANT HEALTH INC | -- | $633,895.00 | 4,850 | BFXC911 |
| 0.88% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $597,112.32 | 3,712 | 2623911 |
| 0.77% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $522,408.25 | 2,275 | B4Q5ZN4 |
| 0.74% | EXEL | EXELIXIS INC | -- | $504,768.00 | 9,600 | 2576941 |
| 0.72% | MEDP | MEDPACE HOLDINGS INC | -- | $489,482.23 | 1,051 | BDCBC61 |
| 0.71% | BBIO | BRIDGEBIO PHARMA INC | -- | $483,091.64 | 7,167 | BK1KWG8 |
| 0.70% | ASND | ASCENDIS PHARMA A/S | -- | $477,482.04 | 2,276 | BWXJHM8 |
| 0.69% | AXSM | AXSOME THERAPEUTICS INC | -- | $465,582.60 | 1,890 | BYZR4X4 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $447,911.88 | 6,109 | BDJ0LS6 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $399,368.70 | 7,110 | 2437071 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $399,208.04 | 847 | BD59BS7 |
| 0.58% | SNY | SANOFI-ADR | -- | $394,177.79 | 9,047 | 2964557 |
| 0.55% | SMMT | SUMMIT THERAPEUTICS INC | -- | $374,065.20 | 28,664 | BMTVQS7 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $366,239.94 | 5,178 | BYQBFJ8 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $362,949.95 | 4,213 | BK6H543 |
| 0.50% | KRYS | KRYSTAL BIOTECH INC | -- | $337,402.80 | 1,080 | BD6JX35 |
| 0.49% | NUVL | NUVALENT INC-A | -- | $333,661.75 | 2,705 | BMVBZD3 |
| 0.47% | TEM | TEMPUS AI INC-CL A | -- | $317,859.52 | 6,424 | BSLSJJ0 |
| 0.46% | ONC | BEONE MEDICINES LTD-ADR | -- | $311,323.41 | 1,181 | BYYWPW6 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $307,662.00 | 4,364 | 2975098 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $305,369.71 | 4,553 | BBBSBJ5 |
| 0.40% | ALKS | ALKERMES PLC | -- | $270,185.92 | 6,163 | B3P6D26 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $265,295.84 | 38,008 | BNSP0B8 |
| 0.37% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $249,722.97 | 2,361 | BDCBCD8 |
| 0.36% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $247,639.14 | 1,029 | BQ721R4 |
| 0.36% | PCVX | VAXCYTE INC | -- | $241,679.82 | 5,321 | BKPVGH6 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $236,019.91 | 3,017 | BMPRZV5 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $234,567.14 | 7,523 | BJRFSB7 |
| 0.33% | PTCT | PTC THERAPEUTICS INC | -- | $224,597.70 | 3,062 | B17VCN9 |
| 0.33% | ABVX | ABIVAX SA-ADR | -- | $222,626.13 | 2,271 | BLC89B2 |
| 0.32% | SYRE | SPYRE THERAPEUTICS INC | -- | $218,107.40 | 2,905 | BQBBDY8 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $216,503.46 | 2,526 | BF2YWG4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $209,714.00 | 2,231 | BJDX8Y8 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $188,342.76 | 6,002 | BLR6XK8 |
| 0.27% | LGND | LIGAND PHARMACEUTICALS | -- | $182,704.64 | 736 | 2501578 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $178,995.96 | 10,431 | BT18HP9 |
| 0.26% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $178,202.24 | 11,632 | BFNF1D6 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $176,128.16 | 4,624 | BTZRLN8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,548.87 | 4,423 | BLB0YQ9 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $175,512.00 | 3,550 | BDHF4K6 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $171,515.16 | 3,123 | BRBCSP4 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $167,756.16 | 2,028 | BM9HHL5 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $166,351.57 | 3,773 | BFZQ0L8 |
| 0.23% | TVTX | TRAVERE THERAPEUTICS INC | -- | $159,336.66 | 3,409 | BLFGJD5 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $157,819.16 | 3,074 | BRJ3GY4 |
| 0.23% | TWST | TWIST BIOSCIENCE CORP | -- | $153,566.82 | 2,266 | BGKG6G7 |
| 0.23% | ERAS | ERASCA INC | -- | $153,006.28 | 11,444 | BNLYBF3 |
| 0.21% | TNGX | TANGO THERAPEUTICS INC | -- | $142,769.04 | 4,978 | BP2P6L0 |
| 0.21% | VCYT | VERACYTE INC | -- | $141,523.46 | 2,938 | BFTWZY0 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $133,938.75 | 6,303 | 2713317 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $132,887.04 | 3,872 | BDD19F8 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $130,560.72 | 3,966 | BKY5JZ8 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $126,657.61 | 4,351 | BKS3RS7 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $124,711.16 | 4,252 | BP8JSP4 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $120,836.43 | 5,863 | BD2B4V0 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $119,606.40 | 2,880 | BQS9486 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $114,549.67 | 1,789 | BKVF0J2 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $111,088.83 | 3,767 | BK6L288 |
| 0.16% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $108,832.92 | 3,122 | BMX9K07 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $107,557.29 | 6,087 | BN15WD1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $106,556.01 | 4,587 | BKX9VD3 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $97,162.44 | 5,692 | BJ5FZ74 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $96,377.71 | 1,573 | BMH5RL1 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $95,590.80 | 2,120 | B72ZBG4 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $94,889.75 | 1,411 | BMGJZJ8 |
| 0.14% | ALMS | ALUMIS INC | -- | $93,760.44 | 4,674 | BPLQG36 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $89,589.60 | 3,246 | BK0VHF6 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $89,114.94 | 6,606 | BN2R582 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $85,639.40 | 3,685 | BV2DHY6 |
| 0.12% | GRAL | GRAIL INC | -- | $84,311.01 | 1,439 | BSLSSX7 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $83,660.46 | 1,698 | BRXB0C0 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $83,350.32 | 2,636 | BL55460 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $82,025.87 | 3,571 | BJ62Z18 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $81,252.00 | 2,196 | BMFD115 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $76,953.24 | 4,914 | BFWLC09 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $75,929.49 | 9,271 | 2100362 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $75,927.20 | 2,140 | BKSGZN7 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $74,666.40 | 8,805 | B9NSBM2 |
| 0.11% | PHVS | PHARVARIS NV | -- | $74,584.17 | 2,367 | BMZ2X38 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $70,829.55 | 2,255 | BFXC933 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,348.26 | 8,049 | BNZB1X8 |
| 0.10% | VCEL | VERICEL CORP | -- | $70,087.50 | 1,875 | BSBMN89 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $70,079.85 | 4,209 | BYSS4X4 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $69,498.00 | 2,925 | BP9N0G0 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,935.50 | 830 | BCDWBX6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $63,542.80 | 4,742 | BJH9ZN0 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $63,203.10 | 2,766 | BPCQZY9 |
| 0.09% | INVA | INNOVIVA INC | -- | $63,020.00 | 2,740 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,554.08 | 2,166 | BCBVTX1 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $62,110.44 | 1,764 | BR3T9B6 |
| 0.09% | QURE | UNIQURE NV | -- | $61,820.10 | 2,305 | BJFSR88 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $60,121.28 | 2,111 | BJQ05Z6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $58,662.88 | 19,297 | BM9FJ13 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $58,551.25 | 3,875 | B8DPDT7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $58,261.71 | 2,379 | BBC9WC7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $58,170.60 | 3,802 | BMVLGP2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,576.96 | 15,232 | BF0DMK7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $57,328.38 | 3,261 | BN7Q7R7 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $57,053.81 | 11,209 | BL53SR3 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $56,454.70 | 3,455 | BRXYZ57 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $56,183.53 | 1,651 | BQKXDX4 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $54,691.20 | 10,128 | BNC1BX1 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $54,634.14 | 4,059 | BPCK358 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $53,301.80 | 4,369 | BYZM6C2 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $53,298.30 | 1,023 | BDRW1L7 |
| 0.08% | NVAX | NOVAVAX INC | -- | $51,556.88 | 6,023 | BJDQXG4 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $51,381.42 | 1,658 | BQXJKH2 |
| 0.07% | PGEN | PRECIGEN INC | -- | $50,881.20 | 13,080 | BKM5C84 |
| 0.07% | ARDX | ARDELYX INC | -- | $50,860.26 | 9,066 | BN89V40 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $50,761.62 | 13,429 | BWJDYK1 |
| 0.07% | ALVO | ALVOTECH SA | -- | $50,549.40 | 12,210 | BPNTJ34 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,488.79 | 1,657 | BQNKXX2 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $50,179.08 | 1,974 | BMVNDH9 |
| 0.07% | HROW | HARROW INC | -- | $49,183.00 | 1,370 | BHNDW86 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $48,440.00 | 1,730 | BZ7PJQ1 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $48,045.39 | 537 | BNSP8K3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $47,932.50 | 5,810 | BK4PZ38 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $47,352.03 | 2,343 | BQB42F1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $46,705.84 | 2,294 | BP6C0S2 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,558.23 | 1,527 | BMGTLY5 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $46,553.36 | 2,818 | BP7KZP7 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,225.90 | 1,621 | BLCD809 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $42,067.48 | 1,778 | BSRK699 |
| 0.06% | MNKD | MANNKIND CORP | -- | $41,342.07 | 11,389 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,159.14 | 6,134 | BLR7H87 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,785.60 | 1,172 | BX7RSN3 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $39,393.60 | 6,960 | BYZG9R0 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $38,461.61 | 3,487 | BMC3HS7 |
| 0.06% | SVRA | SAVARA INC | -- | $38,297.16 | 7,524 | BYXGN81 |
| 0.06% | EYPT | EYEPOINT INC | -- | $37,754.46 | 3,062 | BMGS7L1 |
| 0.05% | PSNL | PERSONALIS INC | -- | $37,181.09 | 3,869 | BJQ0608 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $35,515.53 | 1,983 | BQB42H3 |
| 0.05% | ABSI | ABSCI CORP | -- | $35,479.18 | 5,561 | BN94K69 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $35,012.90 | 1,495 | B3X26D8 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $34,082.64 | 3,054 | BYP80F1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $34,026.33 | 1,677 | BNFWZS4 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,854.56 | 3,656 | BMCR7V2 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,013.20 | 4,510 | B8K7T65 |
| 0.05% | XNCR | XENCOR INC | -- | $32,071.13 | 2,711 | BGCYWN8 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $30,702.40 | 992 | BGL0JK3 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,693.75 | 1,875 | BMNDK09 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $29,600.65 | 2,251 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $29,293.20 | 7,110 | BZ0QMB7 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $29,086.84 | 2,962 | BMZ4LN0 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,595.84 | 2,912 | BJLKVS6 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $28,120.50 | 2,083 | BLFBZ32 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $27,980.94 | 3,711 | BKVDFF7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $27,932.24 | 3,218 | BYZD465 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $27,774.18 | 9,849 | BMFJJ97 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,748.18 | 8,837 | BBNBTD2 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,482.80 | 5,410 | BMCWKZ2 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,191.50 | 2,975 | BFYQFJ2 |
| 0.04% | OMER | OMEROS CORP | -- | $26,744.40 | 2,622 | B4NB858 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,689.20 | 1,934 | BQS7491 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $26,329.25 | 2,185 | BM90J52 |
| 0.04% | GERN | GERON CORP | -- | $25,962.20 | 23,602 | 2370381 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $25,858.91 | 3,053 | BDDVW37 |
| 0.04% | CRMD | CORMEDIX INC | -- | $25,529.47 | 2,911 | BJ0LT31 |
| 0.04% | ANNX | ANNEXON INC | -- | $25,247.28 | 5,349 | BMVV9R5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $24,829.92 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,790.34 | 763 | BL95N25 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,188.00 | 1,100 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,603.45 | 2,707 | BP0TQC5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,439.30 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,902.94 | 1,269 | BD9GVY0 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,771.52 | 672 | BQD3J33 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $20,193.80 | 6,028 | B3MZ6K5 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $19,968.00 | 1,536 | BRJJYT3 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,438.65 | 693 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $19,036.80 | 2,880 | BQHN6C7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $18,281.90 | 4,459 | BYV2W40 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,231.15 | 6,265 | BYWVTY5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,083.83 | 6,673 | BPBJFM7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,998.89 | 4,511 | BYVQJ96 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,797.66 | 1,023 | BS2CR64 |
| 0.02% | ARVN | ARVINAS INC | -- | $16,493.74 | 2,363 | BDZ30Q0 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,437.20 | 1,885 | BKLXFX5 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,177.92 | 2,112 | BSMLR16 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,107.84 | 2,397 | BDRJH21 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,993.71 | 571 | BS2F741 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $15,732.99 | 1,989 | B91XRN2 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,678.28 | 548 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,386.14 | 2,134 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,293.31 | 11,163 | B4N8MH9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $14,788.24 | 8,308 | BFZNYB7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,375.88 | 2,349 | BP81R42 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,966.83 | 3,609 | BKX9NQ0 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,808.16 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,190.58 | 1,879 | B7F2TY6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,181.58 | 2,186 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,701.20 | 1,124 | BPRBTY7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,682.71 | 2,889 | BLN9Z50 |
| 0.02% | OABI | OMNIAB INC | -- | $12,666.36 | 5,322 | BN13S71 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,542.40 | 1,072 | B9L5200 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,541.16 | 1,997 | BRCFFK6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,086.91 | 4,631 | BFY7DC4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,536.56 | 2,646 | 2107437 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,481.49 | 1,873 | BZ0G875 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,171.25 | 1,125 | BM7V485 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,138.61 | 2,697 | BQ6C357 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,972.72 | 7,414 | BFMLGR4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $10,813.28 | 3,557 | BK5MWR1 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,433.80 | 4,013 | BDFKQ07 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,416.00 | 1,736 | BL5B6Z1 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,404.14 | 787 | BTNMG41 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,881.60 | 6,176 | BN4JN37 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,562.24 | 7,136 | BMYTJP4 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,357.04 | 2,387 | BMVBZF5 |
| 0.01% | IVVD | INVIVYD INC | -- | $9,228.82 | 10,244 | BM8NHS1 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,955.28 | 3,611 | BZ8FPH3 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,855.07 | 1,981 | BP7L561 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,648.64 | 2,464 | BJDX8Z9 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,453.52 | 1,416 | BP81RK8 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,427.96 | 3,426 | BYTYP72 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,397.78 | 2,089 | BPRB2N7 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,335.25 | 2,165 | BMF7DT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,892.03 | 1,387 | 2517058 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $7,888.52 | 3,721 | BZC0D70 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,851.35 | 3,341 | B5LL2C2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,619.64 | 1,158 | BQV0J03 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,514.00 | 5,525 | BRK0149 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,455.50 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,248.28 | 1,052 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,234.28 | 2,179 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,895.33 | 1,711 | BKDQKM6 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,843.20 | 7,230 | BNR5QT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,351.03 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,182.66 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,594.78 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,717.96 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,894.25 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,846.01 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,506.58 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,825.06 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,797.92 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,334.58 | 8,555 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 29.92% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,311,420 | -- | 3,524 | -- |
| 29.39% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 19,948,304 | -- | 3,461 | -- |
| 26.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 17,723,501 | -- | 3,075 | -- |
| 22.41% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,210,510 | -- | 2,639 | -- |
| 21.34% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,484,279 | -- | 2,513 | -- |
| 5.37% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,648,447 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $18,252,887.14 | 18,252,887 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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