BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/19/2026- NAV $87.42
- NAV Change $+0.39
- Market Price $87.38
- Market Price Change $+0.33
- Trading Volume (M) 9,740
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/19/2026- NAV $87.42
- NAV Change $+0.39
- Market Price $87.38
- Market Price Change $+0.33
- Trading Volume (M) 9,740
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/19/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.66% | GILD | GILEAD SCIENCES INC | -- | $6,114,768.56 | 40,463 | 2369174 |
| 6.03% | AMGN | AMGEN INC | -- | $5,534,494.50 | 14,739 | 2023607 |
| 6.00% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,510,637.61 | 11,743 | 2931034 |
| 4.12% | REGN | REGENERON PHARMACEUTICALS | -- | $3,779,043.84 | 4,836 | 2730190 |
| 2.29% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,099,342.82 | 6,186 | B00FWN1 |
| 1.75% | INSM | INSMED INC | -- | $1,607,746.00 | 9,986 | 2614487 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,319,397.52 | 6,869 | 2455965 |
| 1.26% | ARGX | ARGENX SE - ADR | -- | $1,154,815.38 | 1,363 | BDVLM39 |
| 1.06% | UTHR | UNITED THERAPEUTICS CORP | -- | $968,728.32 | 2,016 | 2430412 |
| 1.02% | INCY | INCYTE CORP | -- | $935,102.16 | 9,192 | 2471950 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $930,002.48 | 9,052 | BL71K91 |
| 0.99% | MRNA | MODERNA INC | -- | $909,112.40 | 18,292 | BGSXTS3 |
| 0.98% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $897,724.38 | 20,005 | BMVP7Y0 |
| 0.98% | ROIV | ROIVANT SCIENCES LTD | -- | $896,161.28 | 32,564 | BMW4NZ9 |
| 0.94% | VTRS | VIATRIS INC | -- | $861,769.44 | 53,928 | BMWS3X9 |
| 0.94% | ILMN | ILLUMINA INC | -- | $858,480.00 | 7,154 | 2613990 |
| 0.72% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $661,853.75 | 2,875 | BV9G6B8 |
| 0.70% | GH | GUARDANT HEALTH INC | -- | $644,450.04 | 6,058 | BFXC911 |
| 0.70% | BBIO | BRIDGEBIO PHARMA INC | -- | $638,035.84 | 9,022 | BK1KWG8 |
| 0.69% | IONS | IONIS PHARMACEUTICALS INC | -- | $630,571.68 | 7,584 | BDJ0LS6 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $607,306.80 | 4,668 | 2623911 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $588,854.36 | 1,319 | BDCBC61 |
| 0.64% | SNY | SANOFI-ADR | -- | $587,038.20 | 12,390 | 2964557 |
| 0.62% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $570,462.90 | 8,995 | 2437071 |
| 0.60% | EXEL | EXELIXIS INC | -- | $554,384.64 | 12,554 | 2576941 |
| 0.60% | SMMT | SUMMIT THERAPEUTICS INC | -- | $553,164.72 | 34,856 | BMTVQS7 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $522,728.28 | 4,734 | BK6H543 |
| 0.57% | ONC | BEONE MEDICINES LTD-ADR | -- | $522,503.52 | 1,474 | BYYWPW6 |
| 0.56% | RNA | AVIDITY BIOSCIENCES INC | -- | $514,027.30 | 7,055 | BMWHPY1 |
| 0.53% | TEM | TEMPUS AI INC | -- | $485,316.24 | 8,094 | BSLSJJ0 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $482,483.55 | 2,845 | B4Q5ZN4 |
| 0.51% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $464,392.81 | 1,063 | BD59BS7 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $439,373.00 | 2,360 | BYZR4X4 |
| 0.44% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $406,085.74 | 6,359 | BYQBFJ8 |
| 0.43% | IBRX | IMMUNITYBIO INC | -- | $397,075.98 | 46,118 | BNSP0B8 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $396,652.24 | 5,506 | 2975098 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $388,326.75 | 5,725 | BBBSBJ5 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $388,315.31 | 1,171 | BQ721R4 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $359,983.36 | 2,764 | BLC89B2 |
| 0.39% | KRYS | KRYSTAL BIOTECH INC | -- | $356,705.86 | 1,358 | BD6JX35 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $351,930.92 | 3,382 | BMVBZD3 |
| 0.38% | PCVX | VAXCYTE INC | -- | $351,314.28 | 6,129 | BKPVGH6 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $322,375.00 | 3,125 | BF2YWG4 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $291,418.50 | 3,369 | BMPRZV5 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $275,549.58 | 7,187 | BLR6XK8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $275,449.35 | 13,211 | BT18HP9 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $262,754.10 | 3,759 | B17VCN9 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $253,808.94 | 2,406 | BJDX8Y8 |
| 0.27% | ALKS | ALKERMES PLC | -- | $247,392.00 | 7,731 | B3P6D26 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $243,803.68 | 4,462 | BDHF4K6 |
| 0.26% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $243,204.43 | 2,927 | BDCBCD8 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $227,815.20 | 4,776 | BFZQ0L8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $216,336.52 | 8,207 | BJRFSB7 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $214,897.40 | 14,719 | BFNF1D6 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $213,098.34 | 3,777 | BRBCSP4 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $211,113.63 | 3,129 | BQS9486 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $207,300.10 | 14,446 | B19FQ48 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $201,267.36 | 5,844 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $195,492.00 | 4,443 | BDD19F8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $192,717.93 | 7,921 | 2713317 |
| 0.20% | GRAL | GRAIL INC | -- | $185,292.25 | 1,825 | BSLSSX7 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $183,850.67 | 5,309 | BP8JSP4 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $181,870.08 | 11,144 | B9NSBM2 |
| 0.20% | ACLX | ARCELLX INC | -- | $180,096.71 | 2,707 | BPCJ1Q2 |
| 0.19% | APGE | APOGEE THERAPEUTICS INC | -- | $176,943.31 | 2,567 | BM9HHL5 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $171,787.04 | 922 | 2501578 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $166,400.10 | 4,218 | BMDJ0C9 |
| 0.18% | ERAS | ERASCA INC | -- | $164,588.76 | 13,284 | BNLYBF3 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $160,293.25 | 5,735 | BKX9VD3 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $155,863.44 | 3,618 | BRJ3GY4 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $150,278.87 | 2,863 | BGKG6G7 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $146,281.07 | 4,957 | BKY5JZ8 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $138,988.08 | 6,867 | BD2B4V0 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $137,874.75 | 2,685 | B72ZBG4 |
| 0.15% | SYRE | SPYRE THERAPEUTICS INC | -- | $137,363.73 | 3,633 | BQBBDY8 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $135,054.50 | 4,105 | BK0VHF6 |
| 0.15% | APLS | APELLIS PHARMACEUTICALS INC | -- | $134,998.80 | 5,921 | BYTQ6X1 |
| 0.15% | VCYT | VERACYTE INC | -- | $134,272.28 | 3,701 | BFTWZY0 |
| 0.14% | ALMS | ALUMIS INC | -- | $132,941.16 | 4,552 | BPLQG36 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $132,457.88 | 4,751 | BK6L288 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $130,293.52 | 1,988 | BMH5RL1 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $126,070.65 | 2,991 | BL55460 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $122,737.70 | 4,189 | BLFGJD5 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $114,725.40 | 7,148 | BJ5FZ74 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $112,744.32 | 4,517 | BLB0YQ9 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $112,002.80 | 1,768 | BMGJZJ8 |
| 0.11% | TXG | 10X GENOMICS INC-CLASS A | -- | $104,662.26 | 5,454 | BKS3RS7 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $103,962.30 | 3,705 | BP9N0G0 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $103,055.96 | 7,831 | BYZG9R0 |
| 0.11% | DYN | DYNE THERAPEUTICS INC | -- | $101,976.75 | 6,687 | BN15WD1 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $101,475.12 | 2,253 | BSRK699 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $99,764.55 | 2,115 | BRXB0C0 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $98,606.11 | 4,517 | BJ62Z18 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $92,749.83 | 2,697 | BKSGZN7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $91,939.75 | 2,675 | BJQ05Z6 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $91,202.54 | 4,906 | B8DPDT7 |
| 0.10% | VCEL | VERICEL CORP | -- | $90,386.56 | 2,368 | BSBMN89 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $89,559.00 | 24,075 | BM9FJ13 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,891.20 | 6,173 | BFWLC09 |
| 0.10% | HROW | HARROW INC | -- | $88,121.88 | 1,734 | BHNDW86 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $87,692.23 | 3,683 | BMZ4LN0 |
| 0.09% | PHVS | PHARVARIS NV | -- | $83,972.00 | 2,999 | BMZ2X38 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $83,964.10 | 4,070 | BN7Q7R7 |
| 0.09% | INVA | INNOVIVA INC | -- | $82,763.64 | 3,501 | BDDXF67 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $82,161.20 | 1,052 | BCDWBX6 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $81,713.28 | 3,504 | BPCQZY9 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $79,649.24 | 4,612 | BV2DHY6 |
| 0.09% | MNKD | MANNKIND CORP | -- | $79,510.34 | 14,378 | BF081J4 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $79,099.30 | 2,737 | BBC9WC7 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $78,320.52 | 2,102 | BQXJKH2 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $78,293.67 | 2,499 | BMVNDH9 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $78,040.60 | 2,090 | BQKXDX4 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $78,023.40 | 2,730 | BCBVTX1 |
| 0.08% | TNGX | TANGO THERAPEUTICS INC | -- | $77,879.10 | 6,306 | BP2P6L0 |
| 0.08% | ARDX | ARDELYX INC | -- | $76,680.98 | 11,377 | BN89V40 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,966.60 | 1,297 | BTJZB49 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $74,939.34 | 4,746 | BMVLGP2 |
| 0.08% | PGEN | PRECIGEN INC | -- | $74,717.17 | 16,567 | BKM5C84 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $73,737.84 | 9,858 | 2100362 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,496.14 | 2,267 | BKVF0J2 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $72,698.64 | 2,779 | BMFD115 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,375.12 | 3,942 | BMX9K07 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,090.84 | 5,142 | BPCK358 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $71,898.90 | 8,115 | BN2R582 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $71,876.16 | 1,296 | BDRW1L7 |
| 0.08% | QURE | UNIQURE NV | -- | $71,174.80 | 2,917 | BJFSR88 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $70,715.92 | 5,423 | BYZM6C2 |
| 0.08% | NVAX | NOVAVAX INC | -- | $70,193.03 | 7,609 | BJDQXG4 |
| 0.08% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,124.25 | 9,975 | BNZB1X8 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $67,901.26 | 2,513 | BQB42H3 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $67,756.10 | 2,043 | BLCD809 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $66,937.68 | 2,232 | BR3T9B6 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,866.40 | 1,480 | BX7RSN3 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $66,235.86 | 2,484 | BFXC933 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $64,959.10 | 17,005 | BWJDYK1 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $63,402.24 | 6,004 | BJH9ZN0 |
| 0.07% | ALVO | ALVOTECH SA | -- | $63,313.92 | 14,656 | BPNTJ34 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $61,431.75 | 12,825 | BNC1BX1 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $61,418.08 | 2,152 | BNFWZS4 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $61,302.41 | 3,497 | BYP80F1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $59,717.77 | 5,243 | BYSS4X4 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,418.84 | 3,049 | BP7KZP7 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $58,020.49 | 4,807 | BLB0YH0 |
| 0.06% | GERN | GERON CORP | -- | $57,386.88 | 29,889 | 2370381 |
| 0.06% | EYPT | EYEPOINT INC | -- | $56,977.20 | 3,876 | BMGS7L1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $56,759.68 | 2,096 | BQNKXX2 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,215.48 | 681 | BNSP8K3 |
| 0.06% | SVRA | SAVARA INC | -- | $54,494.44 | 9,527 | BYXGN81 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $53,921.28 | 5,712 | B8K7T65 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $52,972.95 | 18,587 | BF0DMK7 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $52,285.37 | 7,769 | BLR7H87 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $51,664.80 | 4,560 | BKVDFF7 |
| 0.06% | SANA | SANA BIOTECHNOLOGY INC | -- | $51,634.08 | 12,472 | BMFJJ97 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,939.48 | 6,514 | BK4PZ38 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,724.15 | 959 | BL95N25 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $47,785.60 | 2,192 | BZ7PJQ1 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $47,629.26 | 4,326 | BRXYZ57 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $46,684.52 | 2,014 | B3X26D8 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,640.36 | 3,341 | BMG99Y1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,107.39 | 2,373 | BMNDK09 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $45,883.20 | 2,904 | BP6C0S2 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $45,128.30 | 14,015 | BL53SR3 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,632.97 | 1,933 | BMGTLY5 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $43,688.32 | 4,628 | BMCR7V2 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $43,393.51 | 7,933 | BYWVTY5 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $42,841.78 | 1,367 | BKLCWZ3 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,905.38 | 3,331 | BJLKVS6 |
| 0.04% | OMER | OMEROS CORP | -- | $39,873.20 | 3,320 | B4NB858 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $39,552.30 | 2,565 | BQB42F1 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $39,399.36 | 11,193 | BBNBTD2 |
| 0.04% | XNCR | XENCOR INC | -- | $39,258.56 | 3,344 | BGCYWN8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,825.36 | 2,296 | BQS7491 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $38,392.08 | 2,766 | BM90J52 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,181.20 | 9,005 | BZ0QMB7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $37,790.72 | 2,816 | BMFX8Y7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $37,611.63 | 2,367 | BD06CS0 |
| 0.04% | ARVN | ARVINAS INC | -- | $37,407.08 | 3,007 | BDZ30Q0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $37,047.78 | 4,158 | BJQ0608 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $36,806.64 | 1,833 | BD9GVY0 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $36,443.12 | 4,412 | BMC3HS7 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $35,114.37 | 7,617 | B3MZ6K5 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,954.92 | 4,074 | BYZD465 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,562.70 | 6,777 | BMVV9R5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,815.06 | 1,679 | BT9K6D8 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $31,404.15 | 3,673 | BDDVW37 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $31,144.00 | 850 | BQD3J33 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $29,723.82 | 2,534 | BJDX8Z9 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,418.26 | 3,769 | BFYQFJ2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,145.16 | 8,452 | BPBJFM7 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,416.76 | 2,667 | BMFK3H6 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $27,224.04 | 7,823 | BN4JN37 |
| 0.03% | CRMD | CORMEDIX INC | -- | $26,118.12 | 3,689 | BJ0LT31 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $24,529.75 | 2,675 | BKLXFX5 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $23,748.48 | 14,136 | B4N8MH9 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $23,600.30 | 1,426 | BM7V485 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,434.04 | 2,636 | BLFBZ32 |
| 0.03% | KMDA | KAMADA LTD | -- | $23,390.66 | 2,701 | B2Q9833 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $23,139.86 | 677 | B292NQ7 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $22,884.32 | 1,256 | BGL0JK3 |
| 0.02% | GOSS | GOSSAMER BIO INC | -- | $22,866.07 | 10,837 | BJ0CK86 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $22,755.60 | 2,520 | B91XRN2 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,699.81 | 3,353 | 2107437 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,619.52 | 5,712 | BYVQJ96 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,411.86 | 10,522 | BFZNYB7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $21,938.14 | 4,886 | BFY7DC4 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $21,606.20 | 2,530 | BRCFFK6 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $21,450.24 | 3,648 | BQHN6C7 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,448.80 | 993 | BTNMG41 |
| 0.02% | PEPG | PEPGEN INC | -- | $21,438.54 | 3,219 | BMTX3D7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,424.59 | 3,417 | BQ6C357 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,913.20 | 6,790 | BMCWKZ2 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,889.75 | 12,975 | BM8NHS1 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,423.90 | 1,790 | BP81RK8 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,931.70 | 2,370 | BZ0G875 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,573.98 | 7,041 | BN94K69 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,924.40 | 5,060 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,914.00 | 1,351 | B9L5200 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $18,396.00 | 876 | BPBPCG8 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $17,653.25 | 1,465 | BQV0J03 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,338.92 | 3,658 | BLN9Z50 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,312.00 | 1,082 | BPRBTY7 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $17,233.96 | 4,183 | BYTYP72 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,878.70 | 2,767 | B12W3P6 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,613.10 | 2,051 | BSMLR16 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,385.79 | 5,073 | BYV2W40 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $16,161.76 | 4,868 | BKRRKY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,017.61 | 2,359 | B7F2TY6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $15,935.28 | 2,973 | BP81R42 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,870.75 | 3,023 | BMVBZF5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,437.84 | 2,648 | BMF7DT9 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $15,402.88 | 9,392 | BFMLGR4 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,291.50 | 2,570 | BP0TQC5 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,151.98 | 4,507 | BK5MWR1 |
| 0.01% | NGNE | NEUROGENE INC | -- | $13,499.50 | 725 | BS2F741 |
| 0.01% | EOLS | EVOLUS INC | -- | $13,414.70 | 3,035 | BDRJH21 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,645.79 | 1,019 | BTXQTX3 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,628.80 | 1,754 | 2517058 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,464.88 | 4,008 | BMXNGZ6 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,999.64 | 2,166 | BKDQKM6 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $11,893.53 | 4,701 | BZC0D70 |
| 0.01% | OABI | OMNIAB INC | -- | $11,525.40 | 6,740 | BN13S71 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,995.00 | 2,199 | BL5B6Z1 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,600.10 | 1,330 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,523.12 | 2,644 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,501.59 | 789 | BRJJYT3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,083.20 | 8,768 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,676.89 | 5,659 | BRK0149 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,620.56 | 4,538 | BKX9NQ0 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,435.78 | 2,759 | BY7RB53 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,796.17 | 9,156 | BNR5QT9 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,273.51 | 4,571 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,811.76 | 1,452 | BP2NYN2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,701.76 | 4,376 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,084.40 | 3,560 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,136.40 | 2,668 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,074.11 | 4,567 | BNNXX18 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,237.54 | 2,506 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $4,990.22 | 4,229 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $4,911.48 | 7,796 | BNNXX52 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $4,459.95 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $19.56 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 41.39% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,993,129 | -- | 6,321 | -- |
| 28.91% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,536,887 | -- | 4,415 | -- |
| 22.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,802,756 | -- | 3,461 | -- |
| 17.28% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,862,026 | -- | 2,639 | -- |
| 16.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,930,380 | -- | 2,484 | -- |
| 4.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,804,722 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,854,701.05 | 28,854,701 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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