BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -1.49% | -14.47% | -20.30% | -6.07% | -4.31% | -1.10% | -4.38% | -4.22% | 13.18% | 04/07/2010 |
| BIB NAV | -1.28% | -14.31% | -20.40% | -5.95% | -4.14% | -1.07% | -4.38% | -4.22% | 13.19% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -12.17% | -4.65% | -23.66% | -4.65% | -14.82% | -7.50% | 1.19% | -4.67% | 13.38% | 04/07/2010 |
| BIB NAV | -12.25% | -4.72% | -23.81% | -4.72% | -14.95% | -7.45% | 1.07% | -4.69% | 13.36% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 5/14/2025- NAV $39.76
- NAV Change $-1.63
- Market Price $39.84
- Market Price Change $-1.64
- Trading Volume (M) 12,417
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 5/14/2025- NAV $39.76
- NAV Change $-1.63
- Market Price $39.84
- Market Price Change $-1.64
- Trading Volume (M) 12,417
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2025
Holdings
as of 5/13/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.24% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,740,176.00 | 6,343 | 2931034 |
| 6.15% | GILD | GILEAD SCIENCES INC | -- | $2,700,370.89 | 26,623 | 2369174 |
| 6.09% | AMGN | AMGEN INC | -- | $2,671,775.55 | 9,879 | 2023607 |
| 5.34% | REGN | REGENERON PHARMACEUTICALS | -- | $2,343,146.96 | 4,081 | 2730190 |
| 3.41% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,496,612.00 | 22,100 | 2989044 |
| 2.99% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,311,083.18 | 4,913 | B00FWN1 |
| 1.57% | SMMT | SUMMIT THERAPEUTICS INC | -- | $689,006.17 | 27,997 | BMTVQS7 |
| 1.56% | BIIB | BIOGEN INC | -- | $684,030.64 | 5,554 | 2455965 |
| 1.50% | ARGX | ARGENX SE - ADR | -- | $659,101.05 | 1,215 | BDVLM39 |
| 1.24% | SNY | SANOFI-ADR | -- | $544,863.76 | 10,906 | 2964557 |
| 1.23% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $539,757.72 | 16,446 | BMVP7Y0 |
| 1.20% | UTHR | UNITED THERAPEUTICS CORP | -- | $524,951.28 | 1,704 | 2430412 |
| 1.10% | ILMN | ILLUMINA INC | -- | $482,683.30 | 6,011 | 2613990 |
| 1.03% | INSM | INSMED INC | -- | $451,361.99 | 6,869 | 2614487 |
| 1.02% | INCY | INCYTE CORP | -- | $446,649.45 | 7,345 | 2471950 |
| 1.01% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $442,352.95 | 3,785 | 2623911 |
| 1.00% | TEM | TEMPUS AI INC | -- | $437,233.95 | 6,345 | BSLSJJ0 |
| 0.99% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $432,807.20 | 7,240 | 2437071 |
| 0.91% | VTRS | VIATRIS INC | -- | $398,222.16 | 45,304 | BMWS3X9 |
| 0.89% | EXEL | EXELIXIS INC | -- | $392,445.95 | 10,621 | 2576941 |
| 0.85% | MRNA | MODERNA INC | -- | $373,224.58 | 14,642 | BGSXTS3 |
| 0.84% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $370,203.84 | 2,292 | BV9G6B8 |
| 0.82% | MEDP | MEDPACE HOLDINGS INC | -- | $358,843.55 | 1,157 | BDCBC61 |
| 0.81% | ONC | BEIGENE LTD-ADR | -- | $357,095.97 | 1,589 | BYYWPW6 |
| 0.81% | BNTX | BIONTECH SE-ADR | -- | $356,926.50 | 3,777 | BK6H543 |
| 0.66% | ROIV | ROIVANT SCIENCES LTD | -- | $291,391.56 | 27,081 | BMW4NZ9 |
| 0.64% | RVMD | REVOLUTION MEDICINES INC | -- | $281,927.15 | 7,057 | BL71K91 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $247,511.68 | 838 | BD59BS7 |
| 0.55% | BPMC | BLUEPRINT MEDICINES CORP | -- | $241,156.53 | 2,426 | BWY52P3 |
| 0.55% | BBIO | BRIDGEBIO PHARMA INC | -- | $240,070.68 | 7,218 | BK1KWG8 |
| 0.54% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $237,104.64 | 2,304 | B4Q5ZN4 |
| 0.54% | HALO | HALOZYME THERAPEUTICS INC | -- | $234,775.02 | 4,674 | 2975098 |
| 0.46% | VRNA | VERONA PHARMA PLC - ADR | -- | $202,034.30 | 2,990 | BYWPZK5 |
| 0.45% | IONS | IONIS PHARMACEUTICALS INC | -- | $196,253.49 | 6,033 | BDJ0LS6 |
| 0.45% | AXSM | AXSOME THERAPEUTICS INC | -- | $195,383.83 | 1,849 | BYZR4X4 |
| 0.44% | GH | GUARDANT HEALTH INC | -- | $193,730.24 | 4,684 | BFXC911 |
| 0.43% | ALKS | ALKERMES PLC | -- | $190,313.64 | 6,171 | B3P6D26 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $179,335.62 | 2,511 | BMVBZD3 |
| 0.41% | ADMA | ADMA BIOLOGICS INC | -- | $178,343.48 | 8,971 | B9NSBM2 |
| 0.34% | KRYS | KRYSTAL BIOTECH INC | -- | $147,175.82 | 1,094 | BD6JX35 |
| 0.33% | PCVX | VAXCYTE INC | -- | $146,854.35 | 4,887 | BKPVGH6 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $138,845.27 | 2,993 | B17VCN9 |
| 0.31% | CYTK | CYTOKINETICS INC | -- | $137,530.73 | 4,493 | BBBSBJ5 |
| 0.31% | RNA | AVIDITY BIOSCIENCES INC | -- | $136,342.44 | 4,563 | BMWHPY1 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $136,239.21 | 2,399 | BF2YWG4 |
| 0.30% | SRPT | SAREPTA THERAPEUTICS INC | -- | $133,324.60 | 3,683 | B8DPDT7 |
| 0.30% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $131,449.68 | 2,844 | BGMGM89 |
| 0.28% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $124,254.00 | 3,510 | BJ62Z18 |
| 0.28% | ACLX | ARCELLX INC | -- | $121,393.00 | 2,084 | BPCJ1Q2 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $121,188.32 | 3,256 | BDHF4K6 |
| 0.28% | AKRO | AKERO THERAPEUTICS INC | -- | $120,910.22 | 3,022 | BK7Y2V9 |
| 0.28% | ALVO | ALVOTECH SA | -- | $120,816.96 | 11,441 | BPNTJ34 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $112,788.80 | 3,592 | BFZQ0L8 |
| 0.25% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $109,315.40 | 3,532 | BDD19F8 |
| 0.25% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $108,858.80 | 6,329 | 2713317 |
| 0.24% | MRUS | MERUS NV | -- | $107,333.16 | 2,623 | BZBY005 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $103,104.83 | 2,329 | BDCBCD8 |
| 0.22% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $96,379.08 | 3,101 | BMX9K07 |
| 0.21% | IMVT | IMMUNOVANT INC | -- | $90,400.96 | 6,448 | BJRFSB7 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $88,230.00 | 11,764 | BFNF1D6 |
| 0.20% | VCYT | VERACYTE INC | -- | $86,669.67 | 2,957 | BFTWZY0 |
| 0.20% | XENE | XENON PHARMACEUTICALS INC | -- | $86,017.60 | 2,906 | BRJ3GY4 |
| 0.19% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $84,156.93 | 1,859 | BJDX8Y8 |
| 0.19% | VCEL | VERICEL CORP | -- | $82,785.08 | 1,897 | BSBMN89 |
| 0.19% | APLS | APELLIS PHARMACEUTICALS INC | -- | $82,321.92 | 4,764 | BYTQ6X1 |
| 0.18% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $79,785.86 | 7,931 | 2100362 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $78,586.86 | 5,511 | BD2B4V0 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $78,150.00 | 4,168 | BP8JSP4 |
| 0.18% | LGND | LIGAND PHARMACEUTICALS | -- | $77,109.90 | 730 | 2501578 |
| 0.17% | KYMR | KYMERA THERAPEUTICS INC | -- | $76,728.96 | 2,464 | BMPRZV5 |
| 0.17% | NVCR | NOVOCURE LTD | -- | $75,680.08 | 4,172 | BYSS4X4 |
| 0.17% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,789.12 | 2,176 | BKSGZN7 |
| 0.17% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $73,145.36 | 4,787 | BYQBFJ8 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $73,104.56 | 2,264 | BGKG6G7 |
| 0.16% | TVTX | TRAVERE THERAPEUTICS INC | -- | $70,525.92 | 3,368 | BLFGJD5 |
| 0.16% | FOLD | AMICUS THERAPEUTICS INC | -- | $70,199.22 | 11,661 | B19FQ48 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $69,856.02 | 2,889 | BRBCSP4 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $69,559.63 | 27,713 | BNSP0B8 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $68,390.73 | 2,119 | B72ZBG4 |
| 0.15% | ZLAB | ZAI LAB LTD-ADR | -- | $67,972.50 | 2,375 | BD9GVY0 |
| 0.15% | APGE | APOGEE THERAPEUTICS INC | -- | $67,836.18 | 1,707 | BM9HHL5 |
| 0.15% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $67,622.94 | 14,994 | BM9FJ13 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,480.76 | 2,174 | BCBVTX1 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $62,231.46 | 4,503 | BKX9VD3 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $60,811.20 | 1,312 | BMGJZJ8 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $60,448.68 | 1,458 | BMH5RL1 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $57,986.35 | 3,323 | BK0VHF6 |
| 0.13% | BEAM | BEAM THERAPEUTICS INC | -- | $57,326.80 | 3,176 | BK6L288 |
| 0.13% | JANX | JANUX THERAPEUTICS INC | -- | $56,789.86 | 2,242 | BMFX8Y7 |
| 0.12% | GRAL | GRAIL INC | -- | $54,727.64 | 1,276 | BSLSSX7 |
| 0.12% | MNKD | MANNKIND CORP | -- | $54,383.84 | 11,522 | BF081J4 |
| 0.12% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $54,015.29 | 2,261 | BQS9486 |
| 0.12% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $53,499.77 | 3,593 | BKY5JZ8 |
| 0.12% | INDV | INDIVIOR PLC | -- | $52,727.28 | 4,712 | BP0BQQ5 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $52,223.60 | 2,420 | BL55460 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $52,042.58 | 5,602 | BJ5FZ74 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $51,945.30 | 4,293 | BN15WD1 |
| 0.12% | ANIP | ANI PHARMACEUTICALS INC | -- | $51,150.00 | 825 | BCDWBX6 |
| 0.11% | SPRY | ARS PHARMACEUTICALS INC | -- | $49,248.15 | 3,689 | BMCR7V2 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $45,300.58 | 4,709 | BRJZSK0 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $43,604.88 | 1,826 | BNFWZS4 |
| 0.10% | INVA | INNOVIVA INC | -- | $43,404.02 | 2,377 | BDDXF67 |
| 0.10% | ETNB | 89BIO INC | -- | $43,219.80 | 5,541 | BK1K484 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $43,173.90 | 3,465 | BLB0YQ9 |
| 0.10% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $42,939.20 | 1,504 | BLCD809 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $41,762.00 | 5,966 | BNZB1X8 |
| 0.09% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,137.20 | 1,758 | B3X26D8 |
| 0.09% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $40,832.00 | 1,595 | BRXB0C0 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $40,757.84 | 5,212 | BFWLC09 |
| 0.09% | TXG | 10X GENOMICS INC-CLASS A | -- | $39,661.50 | 4,110 | BKS3RS7 |
| 0.09% | NVAX | NOVAVAX INC | -- | $37,783.76 | 6,104 | BJDQXG4 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $37,115.59 | 1,853 | BMFD115 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $36,985.32 | 5,788 | BYZG9R0 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $36,391.80 | 4,630 | B8K7T65 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $35,611.00 | 1,195 | BX7RSN3 |
| 0.08% | HROW | HARROW INC | -- | $35,517.04 | 1,352 | BHNDW86 |
| 0.08% | SYRE | SPYRE THERAPEUTICS INC | -- | $33,748.00 | 2,288 | BQBBDY8 |
| 0.08% | AVDL | AVADEL PHARMACEUTICALS | -- | $33,031.74 | 3,658 | BDGMC59 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $33,015.60 | 3,240 | BN7Q7R7 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $32,697.60 | 3,930 | BYZM6C2 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $30,741.52 | 1,592 | BBC9WC7 |
| 0.07% | ARDX | ARDELYX INC | -- | $30,665.94 | 9,046 | BN89V40 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $30,348.54 | 2,614 | BPCQZY9 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $30,205.28 | 1,043 | BQV0J03 |
| 0.07% | GERN | GERON CORP | -- | $29,007.60 | 24,173 | 2370381 |
| 0.07% | CVAC | CUREVAC NV | -- | $28,901.64 | 8,513 | BN4RD42 |
| 0.07% | MLYS | MINERALYS THERAPEUTICS INC | -- | $28,739.48 | 1,892 | BP9N0G0 |
| 0.07% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $28,587.12 | 766 | BQ721R4 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $28,022.40 | 2,880 | BMVLGP2 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $27,724.20 | 5,658 | BLR7H87 |
| 0.06% | CRMD | CORMEDIX INC | -- | $26,772.26 | 2,302 | BJ0LT31 |
| 0.06% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $26,757.68 | 4,045 | BDFKQ07 |
| 0.06% | QURE | UNIQURE NV | -- | $26,298.93 | 2,053 | BJFSR88 |
| 0.06% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $26,211.36 | 3,228 | BYTYP72 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $24,463.50 | 5,205 | BK4PZ38 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $24,448.00 | 1,280 | BMGTLY5 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $24,351.51 | 3,847 | BLB0YH0 |
| 0.06% | EOLS | EVOLUS INC | -- | $24,342.39 | 2,403 | BDRJH21 |
| 0.05% | ANAB | ANAPTYSBIO INC | -- | $23,885.28 | 1,164 | BDRW1L7 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $23,748.90 | 11,309 | BL53SR3 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $22,942.48 | 7,192 | BZ0QMB7 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $22,274.76 | 12,444 | BF0DMK7 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $21,895.36 | 3,392 | BJH9ZN0 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $21,825.00 | 1,875 | BD06CS0 |
| 0.05% | XNCR | XENCOR INC | -- | $21,694.25 | 2,675 | BGCYWN8 |
| 0.05% | REPL | REPLIMUNE GROUP INC | -- | $21,659.43 | 2,923 | BDDVW37 |
| 0.05% | COGT | COGENT BIOSCIENCES INC | -- | $21,561.79 | 4,321 | BLR6XK8 |
| 0.05% | KROS | KEROS THERAPEUTICS INC | -- | $20,743.80 | 1,540 | BM7V485 |
| 0.04% | SVRA | SAVARA INC | -- | $19,346.58 | 6,514 | BYXGN81 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $19,181.56 | 1,922 | BMVNDH9 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $19,015.80 | 773 | BL95N25 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $18,443.49 | 1,083 | BKLCWZ3 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $18,211.05 | 6,435 | BN2R582 |
| 0.04% | TSHA | TAYSHA GENE THERAPIES INC | -- | $18,207.54 | 7,781 | BNC1BX1 |
| 0.04% | STOK | STOKE THERAPEUTICS INC | -- | $17,940.37 | 2,009 | BJQ05Z6 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $17,771.20 | 3,064 | BYZD465 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $17,727.71 | 2,783 | BPQYY97 |
| 0.04% | PSNL | PERSONALIS INC | -- | $17,219.00 | 3,350 | BJQ0608 |
| 0.04% | FTRE | FORTREA HOLDINGS INC | -- | $17,025.00 | 3,405 | BRXYZ57 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $16,924.02 | 2,221 | BM90J52 |
| 0.04% | ALT | ALTIMMUNE INC | -- | $16,836.48 | 2,923 | BFY7DC4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $16,626.06 | 1,866 | BMNDK09 |
| 0.04% | ARVN | ARVINAS INC | -- | $16,416.90 | 2,610 | BDZ30Q0 |
| 0.04% | URGN | UROGEN PHARMA LTD | -- | $16,254.42 | 1,603 | BZ7PJQ1 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,091.46 | 2,709 | 2107437 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $15,944.62 | 2,026 | BLFBZ32 |
| 0.04% | PRTA | PROTHENA CORP PLC | -- | $15,506.37 | 2,043 | B91XRN2 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $15,452.64 | 1,176 | BYXV9H7 |
| 0.04% | SAGE | SAGE THERAPEUTICS INC | -- | $15,421.13 | 2,333 | BP4GNK9 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $15,387.72 | 1,292 | BQS7491 |
| 0.04% | RGNX | REGENXBIO INC | -- | $15,378.40 | 1,880 | BZ0G875 |
| 0.03% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $15,312.81 | 2,591 | BMGS7L1 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $15,274.90 | 2,966 | BFYQFJ2 |
| 0.03% | SANA | SANA BIOTECHNOLOGY INC | -- | $15,210.83 | 8,474 | BMFJJ97 |
| 0.03% | TRML | TOURMALINE BIO INC | -- | $15,120.42 | 973 | BQ80NC6 |
| 0.03% | PGEN | PRECIGEN INC | -- | $15,006.60 | 11,116 | BKM5C84 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $14,923.04 | 556 | B292NQ7 |
| 0.03% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $14,605.97 | 3,253 | BPCK358 |
| 0.03% | ORIC | ORIC PHARMACEUTICALS INC | -- | $14,315.76 | 2,696 | BKVDFF7 |
| 0.03% | ERAS | ERASCA INC | -- | $14,272.23 | 10,731 | BNLYBF3 |
| 0.03% | VERV | VERVE THERAPEUTICS INC | -- | $14,019.20 | 3,370 | BNKGXX2 |
| 0.03% | RAPP | RAPPORT THERAPEUTICS INC | -- | $13,866.12 | 1,388 | BR3T9B6 |
| 0.03% | ORKA | ORUKA THERAPEUTICS INC | -- | $13,670.02 | 1,421 | BKVF0J2 |
| 0.03% | TKNO | ALPHA TEKNOVA INC | -- | $13,635.02 | 2,023 | BP7L561 |
| 0.03% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $13,559.92 | 1,672 | BKDQKM6 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $13,188.24 | 2,818 | BMZ4LN0 |
| 0.03% | ABSI | ABSCI CORP | -- | $12,902.64 | 4,359 | BN94K69 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $12,414.90 | 1,427 | BP81RK8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $12,217.72 | 668 | BQD3J33 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $12,180.22 | 1,027 | BKC9SX3 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $11,951.95 | 10,393 | B4N8MH9 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $11,326.59 | 561 | BPBPCG8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,088.98 | 5,383 | BMCWKZ2 |
| 0.02% | ITOS | ITEOS THERAPEUTICS INC | -- | $10,880.10 | 1,386 | BMWXFT4 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $9,972.96 | 1,896 | BP81R42 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $9,832.80 | 964 | BQB9HM8 |
| 0.02% | OMER | OMEROS CORP | -- | $9,746.00 | 2,200 | B4NB858 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $9,659.62 | 7,606 | BFMLGR4 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $9,487.71 | 2,439 | BYP80F1 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $9,417.24 | 2,331 | BP7KZP7 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $9,346.70 | 3,223 | BMDJ0C9 |
| 0.02% | CMPS | COMPASS PATHWAYS PLC | -- | $9,196.20 | 2,358 | BMC3HS7 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,140.63 | 2,111 | BMF7DT9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,992.54 | 7,958 | BFZNYB7 |
| 0.02% | MXCT | MAXCYTE INC | -- | $8,808.80 | 4,004 | BKMQF66 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $8,807.74 | 2,213 | B12W3P6 |
| 0.02% | THRD | THIRD HARMONIC BIO INC | -- | $8,801.35 | 1,709 | BNNPQY8 |
| 0.02% | NGNE | NEUROGENE INC | -- | $8,747.64 | 564 | BS2F741 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $8,642.97 | 13,719 | BWFZX59 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $8,592.76 | 2,596 | BJLKVS6 |
| 0.02% | HUMA | HUMACYTE INC | -- | $8,447.59 | 4,883 | BMYTJP4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $8,434.41 | 3,207 | BLN9Z50 |
| 0.02% | ATXS | ASTRIA THERAPEUTICS INC | -- | $8,353.80 | 2,142 | BMYRFN8 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $8,082.63 | 2,897 | BQHN6C7 |
| 0.02% | CDXS | CODEXIS INC | -- | $8,046.08 | 3,143 | B5LL2C2 |
| 0.02% | ALMS | ALUMIS INC | -- | $7,987.86 | 1,791 | BPLQG36 |
| 0.02% | SLRN | ACELYRIN INC | -- | $7,985.89 | 3,821 | BQPF874 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $7,923.40 | 3,460 | BYVQJ96 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $7,805.20 | 760 | BN72KB0 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $7,705.88 | 6,643 | BPG5P75 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $7,675.50 | 2,150 | BMFK3H6 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $7,332.24 | 1,784 | BL5B6Z1 |
| 0.02% | ANNX | ANNEXON INC | -- | $7,077.00 | 4,044 | BMVV9R5 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $7,067.84 | 1,699 | BG31GH0 |
| 0.02% | CRGX | CARGO THERAPEUTICS INC | -- | $6,939.56 | 1,748 | BQHN2F2 |
| 0.02% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,802.72 | 2,074 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $6,430.20 | 4,593 | BN13S71 |
| 0.01% | PRME | PRIME MEDICINE INC | -- | $6,323.33 | 4,979 | BPBJFM7 |
| 0.01% | INBX | INHIBRX BIOSCIENCES INC | -- | $6,204.00 | 550 | BNSP8K3 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $5,892.21 | 3,753 | BZC0D70 |
| 0.01% | ESPR | ESPERION THERAPEUTICS INC | -- | $5,838.07 | 7,478 | BBNBTD2 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $5,751.93 | 1,759 | BKLXFX5 |
| 0.01% | TNGX | TANGO THERAPEUTICS INC | -- | $5,745.60 | 4,104 | BP2P6L0 |
| 0.01% | NKTX | NKARTA INC | -- | $5,197.26 | 2,679 | BK80YJ8 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $4,699.50 | 3,133 | BZ8FPH3 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $4,541.25 | 2,422 | BMXNGZ6 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $4,488.00 | 4,488 | BCZS820 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $4,486.61 | 11,089 | BN6MB18 |
| 0.01% | SCPH | SCPHARMACEUTICALS INC | -- | $4,408.00 | 1,900 | BYX2Z16 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $4,231.07 | 809 | B9L5200 |
| 0.01% | ALEC | ALECTOR INC | -- | $4,174.71 | 3,761 | BJ4LDC4 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $4,166.08 | 6,132 | BN4JN37 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $4,156.52 | 6,075 | B3MZ6K5 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $4,041.00 | 2,694 | BKX9NQ0 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $3,797.84 | 1,637 | BSMLR16 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $3,684.66 | 1,302 | BQ6C357 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,666.74 | 2,381 | BFDV8K0 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $3,238.50 | 2,550 | BMW5LX6 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,186.42 | 2,309 | BMDWW66 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $2,685.83 | 2,257 | BLBR8D5 |
| 0.01% | INZY | INOZYME PHARMA INC | -- | $2,658.51 | 2,439 | BMVLGY1 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,551.26 | 3,130 | BF12XC2 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $2,477.79 | 1,863 | BNLYBJ7 |
| 0.01% | BMEA | BIOMEA FUSION INC | -- | $2,241.25 | 1,375 | BNKF6N0 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $1,943.92 | 4,417 | BJL38Z1 |
| -- | PEPG | PEPGEN INC | -- | $1,898.73 | 1,241 | BMTX3D7 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $1,890.10 | 922 | BMF1LJ7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,679.24 | 4,688 | BF3NP05 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $1,488.10 | 1,294 | BKS3SM8 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,334.53 | 1,181 | BP2TPK4 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $918.16 | 499 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $803.88 | 462 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 35.77% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 15,694,534 | -- | 3,930 | -- |
| 25.80% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 11,321,629 | -- | 2,835 | -- |
| 21.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 9,400,746 | -- | 2,354 | -- |
| 17.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 7,663,565 | -- | 1,919 | -- |
| 12.59% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 5,523,038 | -- | 1,383 | -- |
| 11.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 5,211,544 | -- | 1,305 | -- |
| -- | -- | TREASURY BILL | -- | $7,488,530.18 | 7,500,000 | BQC9631 |
| -- | -- | TREASURY BILL | -- | $4,480,459.38 | 4,500,000 | BRBYPQ0 |
| -- | -- | TREASURY BILL | -- | $3,997,180.00 | 4,000,000 | BSZBFQ4 |
| -- | -- | TREASURY BILL | -- | $2,988,057.51 | 3,000,000 | BSNQ2D7 |
| -- | -- | TREASURY BILL | -- | $746,206.15 | 750,000 | BS60BF1 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $-8,916,882.84 | -8,916,883 | -- |
Index
as of 3/31/2025
- Total Number of Companies264
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.80 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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