BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 7/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 10.19% | 6.76% | -8.68% | 0.27% | -23.18% | -0.36% | -5.86% | -6.05% | 13.44% | 04/07/2010 |
| BIB NAV | 10.39% | 6.81% | -8.47% | 0.46% | -23.08% | -0.27% | -5.82% | -6.03% | 13.44% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/03/2025- NAV $57.50
- NAV Change $+0.15
- Market Price $57.45
- Market Price Change $+0.12
- Trading Volume (M) 4,676
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/03/2025- NAV $57.50
- NAV Change $+0.15
- Market Price $57.45
- Market Price Change $+0.12
- Trading Volume (M) 4,676
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/03/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.48% | GILD | GILEAD SCIENCES INC | -- | $2,496,062.09 | 22,091 | 2369174 |
| 4.29% | AMGN | AMGEN INC | -- | $2,395,126.30 | 8,438 | 2023607 |
| 3.91% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,181,410.00 | 5,500 | 2931034 |
| 3.74% | REGN | REGENERON PHARMACEUTICALS | -- | $2,083,804.80 | 3,696 | 2730190 |
| 3.20% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,787,035.42 | 3,994 | B00FWN1 |
| 3.06% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,704,439.38 | 20,758 | 2989044 |
| 1.65% | INSM | INSMED INC | -- | $918,830.50 | 6,403 | 2614487 |
| 1.43% | ARGX | ARGENX SE - ADR | -- | $799,987.08 | 1,108 | BDVLM39 |
| 1.31% | BIIB | BIOGEN INC | -- | $729,343.00 | 5,150 | 2455965 |
| 1.11% | UTHR | UNITED THERAPEUTICS CORP | -- | $620,056.80 | 1,584 | 2430412 |
| 1.10% | SMMT | SUMMIT THERAPEUTICS INC | -- | $613,919.04 | 26,102 | BMTVQS7 |
| 1.06% | INCY | INCYTE CORP | -- | $591,501.92 | 6,802 | 2471950 |
| 0.97% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $542,897.94 | 14,809 | BMVP7Y0 |
| 0.96% | ILMN | ILLUMINA INC | -- | $534,437.41 | 5,563 | 2613990 |
| 0.88% | SNY | SANOFI-ADR | -- | $493,461.99 | 9,891 | 2964557 |
| 0.88% | ONC | BEONE MEDICINES LTD-ADR | -- | $488,585.78 | 1,453 | BYYWPW6 |
| 0.87% | MEDP | MEDPACE HOLDINGS INC | -- | $486,523.53 | 1,011 | BDCBC61 |
| 0.85% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $473,526.69 | 3,479 | 2623911 |
| 0.81% | TEM | TEMPUS AI INC | -- | $450,691.78 | 5,908 | BSLSJJ0 |
| 0.78% | VTRS | VIATRIS INC | -- | $435,208.60 | 41,252 | BMWS3X9 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $426,842.68 | 2,134 | BV9G6B8 |
| 0.71% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $397,466.22 | 6,739 | 2437071 |
| 0.64% | EXEL | EXELIXIS INC | -- | $354,224.64 | 9,584 | 2576941 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $352,474.20 | 3,510 | BK6H543 |
| 0.62% | BBIO | BRIDGEBIO PHARMA INC | -- | $345,876.48 | 6,672 | BK1KWG8 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $339,075.33 | 779 | BD59BS7 |
| 0.61% | IONS | IONIS PHARMACEUTICALS INC | -- | $338,441.55 | 5,595 | BDJ0LS6 |
| 0.59% | MRNA | MODERNA INC | -- | $326,911.65 | 13,593 | BGSXTS3 |
| 0.58% | HALO | HALOZYME THERAPEUTICS INC | -- | $323,970.60 | 4,330 | 2975098 |
| 0.54% | ROIV | ROIVANT SCIENCES LTD | -- | $300,825.46 | 23,894 | BMW4NZ9 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $293,347.71 | 2,763 | BYWPZK5 |
| 0.51% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $285,437.24 | 2,167 | B4Q5ZN4 |
| 0.51% | GH | GUARDANT HEALTH INC | -- | $283,336.30 | 4,355 | BFXC911 |
| 0.47% | RVMD | REVOLUTION MEDICINES INC | -- | $260,294.65 | 6,545 | BL71K91 |
| 0.41% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $227,378.84 | 2,236 | BF2YWG4 |
| 0.38% | AXSM | AXSOME THERAPEUTICS INC | -- | $211,060.00 | 1,730 | BYZR4X4 |
| 0.38% | CYTK | CYTOKINETICS INC | -- | $209,758.04 | 4,196 | BBBSBJ5 |
| 0.36% | RNA | AVIDITY BIOSCIENCES INC | -- | $201,686.42 | 4,238 | BMWHPY1 |
| 0.33% | NUVL | NUVALENT INC-A | -- | $185,407.74 | 2,331 | BMVBZD3 |
| 0.31% | ALKS | ALKERMES PLC | -- | $174,060.00 | 5,802 | B3P6D26 |
| 0.29% | MRUS | MERUS NV | -- | $162,153.08 | 2,434 | BZBY005 |
| 0.29% | CRSP | CRISPR THERAPEUTICS AG | -- | $160,794.30 | 3,035 | BDHF4K6 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $154,706.75 | 2,785 | B17VCN9 |
| 0.27% | KRYS | KRYSTAL BIOTECH INC | -- | $152,753.40 | 1,017 | BD6JX35 |
| 0.27% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $151,285.04 | 5,882 | 2713317 |
| 0.26% | PCVX | VAXCYTE INC | -- | $145,573.50 | 4,535 | BKPVGH6 |
| 0.25% | ADMA | ADMA BIOLOGICS INC | -- | $141,824.80 | 8,392 | B9NSBM2 |
| 0.25% | ACLX | ARCELLX INC | -- | $138,024.36 | 1,938 | BPCJ1Q2 |
| 0.24% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $134,969.00 | 4,855 | BYQBFJ8 |
| 0.23% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $129,896.01 | 1,741 | BJDX8Y8 |
| 0.23% | AKRO | AKERO THERAPEUTICS INC | -- | $127,872.86 | 2,803 | BK7Y2V9 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $126,621.69 | 2,179 | BDCBCD8 |
| 0.22% | APLS | APELLIS PHARMACEUTICALS INC | -- | $122,820.40 | 4,418 | BYTQ6X1 |
| 0.21% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $114,691.68 | 3,336 | BFZQ0L8 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $114,102.45 | 3,293 | BDD19F8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $112,914.12 | 678 | 2501578 |
| 0.19% | INDV | INDIVIOR PLC | -- | $108,153.28 | 4,384 | BP0BQQ5 |
| 0.19% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $105,073.56 | 11,014 | BFNF1D6 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $104,802.17 | 2,699 | BRJ3GY4 |
| 0.19% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $104,777.55 | 3,321 | BJ62Z18 |
| 0.19% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $103,248.40 | 2,872 | BMX9K07 |
| 0.18% | IMVT | IMMUNOVANT INC | -- | $100,316.90 | 6,007 | BJRFSB7 |
| 0.18% | KYMR | KYMERA THERAPEUTICS INC | -- | $99,070.40 | 2,288 | BMPRZV5 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $98,126.72 | 3,944 | BP8JSP4 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $88,377.31 | 1,967 | B72ZBG4 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $85,194.72 | 1,476 | BMH5RL1 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $84,976.25 | 10,825 | B19FQ48 |
| 0.15% | VCYT | VERACYTE INC | -- | $84,327.48 | 2,754 | BFTWZY0 |
| 0.15% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $82,641.35 | 2,035 | BCBVTX1 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $79,263.52 | 3,077 | BK0VHF6 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $78,249.41 | 5,111 | BD2B4V0 |
| 0.14% | CGON | CG ONCOLOGY INC | -- | $76,835.60 | 2,680 | BRBCSP4 |
| 0.14% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $75,660.48 | 2,016 | BKSGZN7 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $74,893.44 | 1,216 | BMGJZJ8 |
| 0.13% | ALVO | ALVOTECH SA | -- | $74,563.05 | 9,379 | BPNTJ34 |
| 0.13% | IBRX | IMMUNITYBIO INC | -- | $73,522.14 | 31,022 | BNSP0B8 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $72,464.00 | 5,600 | BNZB1X8 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,329.04 | 762 | BCDWBX6 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $68,619.00 | 5,340 | BJ5FZ74 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $66,982.50 | 2,290 | BP9N0G0 |
| 0.12% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $66,756.72 | 4,188 | BKX9VD3 |
| 0.12% | BEAM | BEAM THERAPEUTICS INC | -- | $66,335.36 | 3,536 | BK6L288 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,434.35 | 3,453 | B8DPDT7 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $65,046.87 | 14,049 | BM9FJ13 |
| 0.11% | ZLAB | ZAI LAB LTD-ADR | -- | $63,664.20 | 2,034 | BD9GVY0 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $61,666.56 | 1,616 | BM9HHL5 |
| 0.11% | TVTX | TRAVERE THERAPEUTICS INC | -- | $61,242.03 | 3,123 | BLFGJD5 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $60,956.37 | 7,353 | 2100362 |
| 0.11% | VCEL | VERICEL CORP | -- | $59,316.40 | 1,768 | BSBMN89 |
| 0.11% | MNKD | MANNKIND CORP | -- | $58,863.33 | 10,683 | BF081J4 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $56,964.00 | 4,747 | BFWLC09 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $54,756.00 | 2,106 | BGKG6G7 |
| 0.10% | ARDX | ARDELYX INC | -- | $54,729.57 | 8,407 | BN89V40 |
| 0.10% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $54,061.69 | 3,694 | BKY5JZ8 |
| 0.10% | DYN | DYNE THERAPEUTICS INC | -- | $53,879.56 | 3,997 | BN15WD1 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $53,409.87 | 3,357 | BLB0YQ9 |
| 0.09% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $52,794.24 | 1,488 | BRXB0C0 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $52,372.32 | 4,004 | BLR6XK8 |
| 0.09% | TXG | 10X GENOMICS INC-CLASS A | -- | $52,079.36 | 3,904 | BKS3RS7 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $51,476.32 | 2,242 | BL55460 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $49,829.34 | 3,399 | BDGMC59 |
| 0.09% | PGEN | PRECIGEN INC | -- | $49,286.00 | 10,376 | BKM5C84 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,201.65 | 1,395 | BLCD809 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $48,760.99 | 3,023 | BN7Q7R7 |
| 0.09% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $48,669.84 | 1,656 | BNFWZS4 |
| 0.09% | HROW | HARROW INC | -- | $48,131.26 | 1,289 | BHNDW86 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $47,877.12 | 2,078 | BMFX8Y7 |
| 0.08% | ETNB | 89BIO INC | -- | $47,401.20 | 5,130 | BK1K484 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $47,341.52 | 3,919 | BYSS4X4 |
| 0.08% | INVA | INNOVIVA INC | -- | $46,084.50 | 2,205 | BDDXF67 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,776.29 | 1,131 | BX7RSN3 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,249.04 | 1,628 | B3X26D8 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,123.52 | 5,628 | BLR7H87 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $43,352.00 | 5,419 | BYZG9R0 |
| 0.08% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $42,758.73 | 4,221 | BRJZSK0 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $42,600.98 | 3,638 | BYZM6C2 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,408.32 | 7,912 | BN4RD42 |
| 0.08% | NVAX | NOVAVAX INC | -- | $42,120.80 | 5,692 | BJDQXG4 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $41,859.09 | 10,491 | BL53SR3 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $41,253.03 | 2,093 | BQS9486 |
| 0.07% | GRFS | GRIFOLS SA-ADR | -- | $41,121.92 | 4,288 | B8K7T65 |
| 0.07% | GRAL | GRAIL INC | -- | $41,043.72 | 1,266 | BSLSSX7 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $39,888.84 | 1,473 | BBC9WC7 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $38,838.03 | 989 | BQV0J03 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $37,938.63 | 1,919 | BJQ05Z6 |
| 0.07% | SPRY | ARS PHARMACEUTICALS INC | -- | $37,546.88 | 3,451 | BMCR7V2 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $36,117.80 | 1,724 | BMFD115 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $35,670.82 | 2,122 | BQBBDY8 |
| 0.06% | ZYME | ZYMEWORKS INC | -- | $34,657.14 | 2,451 | BPCQZY9 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $34,015.58 | 3,182 | BRXYZ57 |
| 0.06% | QURE | UNIQURE NV | -- | $33,439.12 | 1,924 | BJFSR88 |
| 0.06% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $33,236.70 | 714 | BQ721R4 |
| 0.06% | CRMD | CORMEDIX INC | -- | $32,688.20 | 2,386 | BJ0LT31 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $31,398.77 | 1,621 | BZ7PJQ1 |
| 0.06% | GERN | GERON CORP | -- | $31,340.40 | 22,386 | 2370381 |
| 0.06% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $30,848.40 | 3,135 | BPCK358 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,129.76 | 2,452 | BJLKVS6 |
| 0.05% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $29,028.00 | 2,419 | BMGS7L1 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $28,549.02 | 3,002 | BYTYP72 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $27,271.23 | 714 | BL95N25 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $26,778.60 | 4,860 | BK4PZ38 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $26,658.72 | 3,564 | BLB0YH0 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $26,607.50 | 9,175 | BNC1BX1 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,500.00 | 2,500 | BKVDFF7 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $26,464.62 | 6,734 | BZ0QMB7 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $25,940.98 | 11,738 | BF0DMK7 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $25,652.49 | 3,043 | BYZD465 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $25,561.25 | 3,575 | BJH9ZN0 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $25,533.70 | 3,811 | BP2P6L0 |
| 0.05% | NRIX | NURIX THERAPEUTICS INC | -- | $25,352.80 | 2,680 | BMVLGP2 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,914.69 | 629 | BQD3J33 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $24,766.86 | 6,026 | BN2R582 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $24,751.68 | 1,748 | BD06CS0 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,159.87 | 1,759 | BMNDK09 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $24,054.30 | 2,655 | BPQYY97 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $23,701.73 | 7,927 | BMFJJ97 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,571.20 | 1,016 | BKLCWZ3 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $23,228.43 | 1,031 | BDRW1L7 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $23,164.96 | 1,204 | BMGTLY5 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $23,038.40 | 1,870 | BMVNDH9 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,855.68 | 3,072 | BMDJ0C9 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $22,624.11 | 901 | BQ80NC6 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,505.28 | 1,428 | BM7V485 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,636.93 | 2,513 | 2107437 |
| 0.04% | XNCR | XENCOR INC | -- | $20,849.99 | 2,503 | BGCYWN8 |
| 0.04% | SVRA | SAVARA INC | -- | $20,773.08 | 6,074 | BYXGN81 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $20,692.59 | 2,823 | BFYQFJ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $20,556.48 | 1,596 | BQS7491 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $20,334.48 | 1,317 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $20,279.30 | 2,567 | BDZ30Q0 |
| 0.03% | RAPP | RAPPORT THERAPEUTICS INC | -- | $19,281.28 | 1,282 | BR3T9B6 |
| 0.03% | RGNX | REGENXBIO INC | -- | $17,402.90 | 1,765 | BZ0G875 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $17,144.24 | 1,922 | BLFBZ32 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $16,929.81 | 6,967 | BBNBTD2 |
| 0.03% | EOLS | EVOLUS INC | -- | $16,708.32 | 2,264 | BDRJH21 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $16,613.76 | 1,088 | BYXV9H7 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $16,416.45 | 955 | BKC9SX3 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,317.72 | 522 | B292NQ7 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $16,049.88 | 2,079 | BM90J52 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,963.66 | 2,708 | BDDVW37 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,890.66 | 1,894 | B91XRN2 |
| 0.03% | ALMS | ALUMIS INC | -- | $15,724.80 | 3,360 | BPLQG36 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $15,663.00 | 2,724 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $15,417.44 | 4,616 | BPBJFM7 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,224.58 | 2,709 | BYP80F1 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $15,121.16 | 2,404 | BMZ4LN0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $15,059.25 | 3,105 | BJQ0608 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $15,034.32 | 3,192 | BMC3HS7 |
| 0.03% | ERAS | ERASCA INC | -- | $14,241.37 | 9,959 | BNLYBF3 |
| 0.03% | INBX | INHIBRX BIOSCIENCES INC | -- | $14,178.00 | 510 | BNSP8K3 |
| 0.02% | ATXS | ASTRIA THERAPEUTICS INC | -- | $13,861.17 | 1,983 | BMYRFN8 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $13,821.20 | 2,180 | BP81R42 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $13,793.40 | 3,492 | BYVQJ96 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $13,785.12 | 12,764 | BWFZX59 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $13,650.78 | 1,591 | BG31GH0 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,289.22 | 10,547 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,572.84 | 3,787 | BDFKQ07 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,939.24 | 5,059 | BMCWKZ2 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,896.16 | 1,996 | BMFK3H6 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,012.10 | 1,551 | BKDQKM6 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,805.00 | 2,161 | BP7KZP7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $10,692.88 | 655 | BPBPCG8 |
| 0.02% | ABSI | ABSCI CORP | -- | $10,671.92 | 4,484 | BN94K69 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,603.20 | 705 | BN72KB0 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $10,539.63 | 1,629 | BKLXFX5 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,491.68 | 2,851 | BFY7DC4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $10,414.60 | 3,010 | BLN9Z50 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,313.39 | 1,957 | BMF7DT9 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,239.60 | 1,855 | BYX2Z16 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,146.24 | 7,046 | BFMLGR4 |
| 0.02% | NGNE | NEUROGENE INC | -- | $9,974.74 | 502 | BS2F741 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,947.00 | 5,684 | BN4JN37 |
| 0.02% | ALEC | ALECTOR INC | -- | $9,801.27 | 3,513 | BJ4LDC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,784.56 | 2,073 | B12W3P6 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $9,337.75 | 911 | BQB9HM8 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $8,872.88 | 2,252 | BMXNGZ6 |
| 0.02% | OMER | OMEROS CORP | -- | $8,610.80 | 2,060 | B4NB858 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,610.56 | 7,688 | BFZNYB7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,276.52 | 1,652 | BL5B6Z1 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,985.75 | 1,879 | BP7L561 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $7,975.54 | 3,529 | BZC0D70 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,959.92 | 5,452 | BMYTJP4 |
| 0.01% | ANNX | ANNEXON INC | -- | $7,906.85 | 3,857 | BMVV9R5 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,360.00 | 2,944 | BZ8FPH3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,161.28 | 1,946 | BY7RB53 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,096.88 | 1,334 | BP81RK8 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $7,050.64 | 5,686 | B3MZ6K5 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,017.92 | 2,912 | B5LL2C2 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,632.64 | 752 | B9L5200 |
| 0.01% | OABI | OMNIAB INC | -- | $6,537.52 | 4,301 | BN13S71 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,392.32 | 2,497 | BKX9NQ0 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $5,943.60 | 520 | BTNMG41 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $5,797.44 | 2,376 | BMW5LX6 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,752.96 | 6,464 | BPG5P75 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $5,736.72 | 1,166 | BQ6C357 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,658.12 | 1,521 | BSMLR16 |
| 0.01% | NKTX | NKARTA INC | -- | $5,239.50 | 2,495 | BK80YJ8 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,158.44 | 3,738 | BKMQF66 |
| 0.01% | MGNX | MACROGENICS INC | -- | $4,232.56 | 2,216 | BFDV8K0 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $4,029.00 | 4,029 | BCZS820 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,688.47 | 2,157 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,435.19 | 1,837 | BNLYBJ7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,201.66 | 2,178 | BLBR8D5 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,997.68 | 2,968 | BF12XC2 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,722.08 | 856 | BMF1LJ7 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,546.23 | 4,977 | BJL38Z1 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,538.24 | 1,322 | BNKF6N0 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,475.34 | 1,101 | BP2TPK4 |
| -- | PEPG | PEPGEN INC | -- | $1,366.12 | 1,148 | BMTX3D7 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,279.16 | 452 | BT7KGT6 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,221.50 | 175 | BVPKH99 |
| -- | QTTB | Q32 BIO INC | -- | $731.88 | 428 | BS2FKQ4 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,543,017 | -- | 3,675 | -- |
| 31.38% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 17,500,054 | -- | 3,666 | -- |
| 24.61% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,724,129 | -- | 2,875 | -- |
| 16.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,184,426 | -- | 1,924 | -- |
| 16.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,160,558 | -- | 1,919 | -- |
| 16.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 9,045,991 | -- | 1,895 | -- |
| -- | -- | TREASURY BILL | -- | $4,979,741.30 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $15,602,141.14 | 15,602,141 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Earnings Ratio--
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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