BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View all
Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 8/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.47% | 28.93% | 1.11% | 9.77% | -16.62% | 3.73% | -4.43% | -2.92% | 14.03% | 04/07/2010 |
| BIB NAV | 9.35% | 28.93% | 1.18% | 9.85% | -16.62% | 3.78% | -4.40% | -2.92% | 14.03% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/17/2025- NAV $56.73
- NAV Change $+0.14
- Market Price $56.66
- Market Price Change $+0.11
- Trading Volume (M) 5,997
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/17/2025- NAV $56.73
- NAV Change $+0.14
- Market Price $56.66
- Market Price Change $+0.11
- Trading Volume (M) 5,997
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/17/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.51% | GILD | GILEAD SCIENCES INC | -- | $2,479,935.66 | 22,091 | 2369174 |
| 4.21% | AMGN | AMGEN INC | -- | $2,318,002.98 | 8,438 | 2023607 |
| 3.93% | REGN | REGENERON PHARMACEUTICALS | -- | $2,164,008.00 | 3,696 | 2730190 |
| 3.87% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,129,325.00 | 5,500 | 2931034 |
| 3.28% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,804,189.65 | 3,994 | B00FWN1 |
| 2.93% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,612,689.02 | 20,758 | 2989044 |
| 1.68% | INSM | INSMED INC | -- | $927,026.34 | 6,403 | 2614487 |
| 1.48% | ARGX | ARGENX SE - ADR | -- | $813,659.80 | 1,108 | BDVLM39 |
| 1.36% | BIIB | BIOGEN INC | -- | $746,080.50 | 5,150 | 2455965 |
| 1.16% | UTHR | UNITED THERAPEUTICS CORP | -- | $639,429.12 | 1,584 | 2430412 |
| 1.05% | INCY | INCYTE CORP | -- | $576,809.60 | 6,802 | 2471950 |
| 1.02% | ILMN | ILLUMINA INC | -- | $561,139.81 | 5,563 | 2613990 |
| 0.96% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $527,792.76 | 14,809 | BMVP7Y0 |
| 0.93% | TEM | TEMPUS AI INC | -- | $510,746.60 | 5,908 | BSLSJJ0 |
| 0.91% | MEDP | MEDPACE HOLDINGS INC | -- | $503,306.13 | 1,011 | BDCBC61 |
| 0.90% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $496,557.67 | 3,479 | 2623911 |
| 0.88% | ONC | BEONE MEDICINES LTD-ADR | -- | $482,686.60 | 1,453 | BYYWPW6 |
| 0.86% | SMMT | SUMMIT THERAPEUTICS INC | -- | $472,185.18 | 26,102 | BMTVQS7 |
| 0.84% | SNY | SANOFI-ADR | -- | $464,580.27 | 9,891 | 2964557 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $425,925.06 | 2,134 | BV9G6B8 |
| 0.72% | VTRS | VIATRIS INC | -- | $396,844.24 | 41,252 | BMWS3X9 |
| 0.70% | EXEL | EXELIXIS INC | -- | $387,576.96 | 9,584 | 2576941 |
| 0.67% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $366,399.43 | 6,739 | 2437071 |
| 0.66% | ROIV | ROIVANT SCIENCES LTD | -- | $365,100.32 | 23,894 | BMW4NZ9 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $344,506.50 | 3,510 | BK6H543 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $342,246.15 | 5,595 | BDJ0LS6 |
| 0.62% | BBIO | BRIDGEBIO PHARMA INC | -- | $341,472.96 | 6,672 | BK1KWG8 |
| 0.62% | MRNA | MODERNA INC | -- | $339,825.00 | 13,593 | BGSXTS3 |
| 0.60% | HALO | HALOZYME THERAPEUTICS INC | -- | $328,257.30 | 4,330 | 2975098 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $325,177.97 | 779 | BD59BS7 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $293,679.27 | 2,763 | BYWPZK5 |
| 0.52% | RVMD | REVOLUTION MEDICINES INC | -- | $286,736.45 | 6,545 | BL71K91 |
| 0.51% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $280,713.18 | 2,167 | B4Q5ZN4 |
| 0.45% | GH | GUARDANT HEALTH INC | -- | $249,062.45 | 4,355 | BFXC911 |
| 0.39% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $214,879.60 | 2,236 | BF2YWG4 |
| 0.37% | AXSM | AXSOME THERAPEUTICS INC | -- | $201,752.60 | 1,730 | BYZR4X4 |
| 0.36% | CYTK | CYTOKINETICS INC | -- | $199,561.76 | 4,196 | BBBSBJ5 |
| 0.33% | NUVL | NUVALENT INC-A | -- | $183,309.84 | 2,331 | BMVBZD3 |
| 0.33% | CRSP | CRISPR THERAPEUTICS AG | -- | $179,277.45 | 3,035 | BDHF4K6 |
| 0.31% | RNA | AVIDITY BIOSCIENCES INC | -- | $169,774.28 | 4,238 | BMWHPY1 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $168,910.25 | 2,785 | B17VCN9 |
| 0.30% | MRUS | MERUS NV | -- | $165,937.95 | 2,434 | BZBY005 |
| 0.29% | ALKS | ALKERMES PLC | -- | $161,701.74 | 5,802 | B3P6D26 |
| 0.28% | KRYS | KRYSTAL BIOTECH INC | -- | $156,668.85 | 1,017 | BD6JX35 |
| 0.27% | ACLX | ARCELLX INC | -- | $148,101.96 | 1,938 | BPCJ1Q2 |
| 0.26% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $142,344.40 | 5,882 | 2713317 |
| 0.26% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $141,426.15 | 4,855 | BYQBFJ8 |
| 0.25% | PCVX | VAXCYTE INC | -- | $140,063.48 | 4,535 | BKPVGH6 |
| 0.24% | ADMA | ADMA BIOLOGICS INC | -- | $130,579.52 | 8,392 | B9NSBM2 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $129,040.38 | 2,179 | BDCBCD8 |
| 0.23% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $127,336.74 | 1,741 | BJDX8Y8 |
| 0.21% | AKRO | AKERO THERAPEUTICS INC | -- | $118,230.54 | 2,803 | BK7Y2V9 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $112,620.60 | 3,293 | BDD19F8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $112,147.98 | 678 | 2501578 |
| 0.20% | KYMR | KYMERA THERAPEUTICS INC | -- | $110,098.56 | 2,288 | BMPRZV5 |
| 0.19% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $106,585.20 | 3,336 | BFZQ0L8 |
| 0.19% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $105,844.54 | 11,014 | BFNF1D6 |
| 0.19% | APLS | APELLIS PHARMACEUTICALS INC | -- | $102,188.34 | 4,418 | BYTQ6X1 |
| 0.18% | CGON | CG ONCOLOGY INC | -- | $101,089.60 | 2,680 | BRBCSP4 |
| 0.18% | INDV | INDIVIOR PLC | -- | $100,700.48 | 4,384 | BP0BQQ5 |
| 0.18% | XENE | XENON PHARMACEUTICALS INC | -- | $99,053.30 | 2,699 | BRJ3GY4 |
| 0.18% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $98,997.84 | 2,872 | BMX9K07 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $96,588.56 | 3,944 | BP8JSP4 |
| 0.17% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $95,345.91 | 3,321 | BJ62Z18 |
| 0.16% | IMVT | IMMUNOVANT INC | -- | $90,765.77 | 6,007 | BJRFSB7 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $88,121.60 | 1,967 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $87,659.82 | 2,754 | BFTWZY0 |
| 0.16% | FOLD | AMICUS THERAPEUTICS INC | -- | $86,275.25 | 10,825 | B19FQ48 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $85,620.72 | 31,022 | BNSP0B8 |
| 0.16% | MLYS | MINERALYS THERAPEUTICS INC | -- | $85,394.10 | 2,290 | BP9N0G0 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $79,383.20 | 3,536 | BK6L288 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $76,294.44 | 1,476 | BMH5RL1 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $75,201.88 | 3,077 | BK0VHF6 |
| 0.14% | ALVO | ALVOTECH SA | -- | $74,375.47 | 9,379 | BPNTJ34 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $74,218.56 | 1,216 | BMGJZJ8 |
| 0.13% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,114.70 | 2,035 | BCBVTX1 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $73,858.95 | 3,123 | BLFGJD5 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $73,350.45 | 3,357 | BLB0YQ9 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,660.51 | 762 | BCDWBX6 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $71,782.32 | 4,188 | BKX9VD3 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $68,458.80 | 5,340 | BJ5FZ74 |
| 0.12% | OCUL | OCULAR THERAPEUTIX INC | -- | $68,124.00 | 5,600 | BNZB1X8 |
| 0.12% | DNLI | DENALI THERAPEUTICS INC | -- | $66,749.66 | 5,111 | BD2B4V0 |
| 0.12% | ZLAB | ZAI LAB LTD-ADR | -- | $66,267.72 | 2,034 | BD9GVY0 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $66,170.79 | 14,049 | BM9FJ13 |
| 0.12% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $64,632.96 | 2,016 | BKSGZN7 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $60,810.08 | 1,616 | BM9HHL5 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $58,873.65 | 3,453 | B8DPDT7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $58,388.10 | 4,747 | BFWLC09 |
| 0.10% | MNKD | MANNKIND CORP | -- | $57,581.37 | 10,683 | BF081J4 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $56,798.82 | 2,106 | BGKG6G7 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $56,618.10 | 7,353 | 2100362 |
| 0.10% | HROW | HARROW INC | -- | $55,620.35 | 1,289 | BHNDW86 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $55,018.68 | 2,242 | BL55460 |
| 0.10% | AVDL | AVADEL PHARMACEUTICALS | -- | $53,228.34 | 3,399 | BDGMC59 |
| 0.10% | VCEL | VERICEL CORP | -- | $53,075.36 | 1,768 | BSBMN89 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $52,719.84 | 1,488 | BRXB0C0 |
| 0.10% | DYN | DYNE THERAPEUTICS INC | -- | $52,560.55 | 3,997 | BN15WD1 |
| 0.09% | ARDX | ARDELYX INC | -- | $52,039.33 | 8,407 | BN89V40 |
| 0.09% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $51,309.66 | 3,694 | BKY5JZ8 |
| 0.09% | TXG | 10X GENOMICS INC-CLASS A | -- | $50,205.44 | 3,904 | BKS3RS7 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $49,732.11 | 3,919 | BYSS4X4 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $49,489.44 | 4,004 | BLR6XK8 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $48,749.88 | 2,078 | BMFX8Y7 |
| 0.09% | GRAL | GRAIL INC | -- | $48,513.12 | 1,266 | BSLSSX7 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,943.87 | 10,491 | BL53SR3 |
| 0.09% | NVAX | NOVAVAX INC | -- | $47,755.88 | 5,692 | BJDQXG4 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,613.93 | 1,395 | BLCD809 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $45,313.45 | 2,093 | BQS9486 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $45,147.58 | 3,638 | BYZM6C2 |
| 0.08% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $44,678.88 | 1,656 | BNFWZS4 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $44,589.25 | 3,023 | BN7Q7R7 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $43,638.06 | 1,919 | BJQ05Z6 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,166.76 | 5,628 | BLR7H87 |
| 0.08% | TRML | TOURMALINE BIO INC | -- | $42,977.70 | 901 | BQ80NC6 |
| 0.08% | INVA | INNOVIVA INC | -- | $42,732.90 | 2,205 | BDDXF67 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,441.96 | 1,628 | B3X26D8 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,408.32 | 7,912 | BN4RD42 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $41,808.00 | 4,288 | B8K7T65 |
| 0.08% | LENZ | LENZ THERAPEUTICS INC | -- | $41,765.47 | 989 | BQV0J03 |
| 0.08% | ETNB | 89BIO INC | -- | $41,450.40 | 5,130 | BK1K484 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $41,361.84 | 1,473 | BBC9WC7 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $40,394.97 | 4,221 | BRJZSK0 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,195.74 | 1,131 | BX7RSN3 |
| 0.07% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $40,033.95 | 3,135 | BPCK358 |
| 0.07% | PGEN | PRECIGEN INC | -- | $39,636.32 | 10,376 | BKM5C84 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $38,897.37 | 2,451 | BPCQZY9 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $36,849.20 | 5,419 | BYZG9R0 |
| 0.06% | RAPP | RAPPORT THERAPEUTICS INC | -- | $33,716.60 | 1,282 | BR3T9B6 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,026.07 | 3,451 | BMCR7V2 |
| 0.06% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $32,995.16 | 2,419 | BMGS7L1 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $32,806.42 | 3,182 | BRXYZ57 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $32,790.48 | 1,724 | BMFD115 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $31,936.10 | 2,122 | BQBBDY8 |
| 0.06% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $31,437.42 | 714 | BQ721R4 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $29,831.62 | 6,734 | BZ0QMB7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $29,340.10 | 1,621 | BZ7PJQ1 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $29,039.82 | 3,811 | BP2P6L0 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $28,528.50 | 3,575 | BJH9ZN0 |
| 0.05% | GERN | GERON CORP | -- | $28,430.22 | 22,386 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $27,546.12 | 714 | BL95N25 |
| 0.05% | QURE | UNIQURE NV | -- | $27,243.84 | 1,924 | BJFSR88 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $26,972.00 | 2,452 | BJLKVS6 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $26,607.50 | 9,175 | BNC1BX1 |
| 0.05% | CRMD | CORMEDIX INC | -- | $26,532.32 | 2,386 | BJ0LT31 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $26,357.56 | 3,002 | BYTYP72 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,300.00 | 2,500 | BKVDFF7 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $26,058.36 | 11,738 | BF0DMK7 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $25,408.35 | 2,655 | BPQYY97 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $24,912.36 | 3,564 | BLB0YH0 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,713.95 | 1,759 | BMNDK09 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $24,646.34 | 6,026 | BN2R582 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $24,617.87 | 3,043 | BYZD465 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $24,098.08 | 7,927 | BMFJJ97 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $24,051.72 | 1,596 | BQS7491 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $23,388.24 | 1,748 | BD06CS0 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $23,328.00 | 4,860 | BK4PZ38 |
| 0.04% | XNCR | XENCOR INC | -- | $23,152.75 | 2,503 | BGCYWN8 |
| 0.04% | NRIX | NURIX THERAPEUTICS INC | -- | $22,967.60 | 2,680 | BMVLGP2 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,732.80 | 3,072 | BMDJ0C9 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $22,720.50 | 1,870 | BMVNDH9 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,305.36 | 1,428 | BM7V485 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,169.12 | 1,016 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $21,866.40 | 6,074 | BYXGN81 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,762.58 | 2,513 | 2107437 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,524.38 | 629 | BQD3J33 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $21,464.40 | 4,616 | BPBJFM7 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $21,348.57 | 1,317 | BKVF0J2 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $21,082.04 | 1,204 | BMGTLY5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $20,692.59 | 2,823 | BFYQFJ2 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $20,424.11 | 1,031 | BDRW1L7 |
| 0.04% | ARVN | ARVINAS INC | -- | $19,534.87 | 2,567 | BDZ30Q0 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $19,018.24 | 1,088 | BYXV9H7 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,950.24 | 6,967 | BBNBTD2 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $18,631.00 | 2,404 | BMZ4LN0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $17,791.65 | 3,105 | BJQ0608 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $17,237.75 | 955 | BKC9SX3 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $16,866.36 | 3,492 | BYVQJ96 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,839.72 | 522 | B292NQ7 |
| 0.03% | ERAS | ERASCA INC | -- | $16,631.53 | 9,959 | BNLYBF3 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $16,087.68 | 3,192 | BMC3HS7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $15,937.95 | 1,765 | BZ0G875 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,685.11 | 2,709 | BYP80F1 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,462.68 | 2,708 | BDDVW37 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,265.64 | 1,894 | B91XRN2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $14,900.28 | 2,724 | BQHN6C7 |
| 0.03% | EOLS | EVOLUS INC | -- | $14,761.28 | 2,264 | BDRJH21 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,654.37 | 1,983 | BMYRFN8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $14,215.79 | 5,059 | BMCWKZ2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $14,088.26 | 1,922 | BLFBZ32 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $13,912.76 | 12,764 | BWFZX59 |
| 0.03% | ALMS | ALUMIS INC | -- | $13,876.80 | 3,360 | BPLQG36 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $13,743.96 | 2,161 | BP7KZP7 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $13,532.85 | 510 | BNSP8K3 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $13,298.00 | 2,180 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $12,972.81 | 10,547 | B4N8MH9 |
| 0.02% | CGEM | CULLINAN THERAPEUTICS INC | -- | $12,328.47 | 2,079 | BM90J52 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,876.20 | 1,996 | BMFK3H6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,474.61 | 3,787 | BDFKQ07 |
| 0.02% | ABSI | ABSCI CORP | -- | $11,434.20 | 4,484 | BN94K69 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $10,849.14 | 1,629 | BKLXFX5 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,732.92 | 1,551 | BKDQKM6 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,443.65 | 1,855 | BYX2Z16 |
| 0.02% | ALEC | ALECTOR INC | -- | $10,363.35 | 3,513 | BJ4LDC4 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,293.00 | 705 | BN72KB0 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,178.07 | 2,851 | BFY7DC4 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $9,864.30 | 655 | BPBPCG8 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,719.64 | 3,857 | BMVV9R5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,393.60 | 1,957 | BMF7DT9 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,188.16 | 2,252 | BMXNGZ6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,100.47 | 2,073 | B12W3P6 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $8,948.42 | 7,046 | BFMLGR4 |
| 0.02% | NGNE | NEUROGENE INC | -- | $8,890.42 | 502 | BS2F741 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $8,759.10 | 3,010 | BLN9Z50 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,687.44 | 7,688 | BFZNYB7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $8,681.34 | 3,529 | BZC0D70 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $8,439.86 | 2,497 | BKX9NQ0 |
| 0.02% | OMER | OMEROS CORP | -- | $8,363.60 | 2,060 | B4NB858 |
| 0.02% | HUMA | HUMACYTE INC | -- | $8,341.56 | 5,452 | BMYTJP4 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,335.65 | 911 | BQB9HM8 |
| 0.02% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,289.96 | 1,946 | BY7RB53 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,276.52 | 1,652 | BL5B6Z1 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $8,267.60 | 1,879 | BP7L561 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $8,241.80 | 5,684 | BN4JN37 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,007.68 | 2,944 | BZ8FPH3 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $7,278.08 | 5,686 | B3MZ6K5 |
| 0.01% | OABI | OMNIAB INC | -- | $6,967.62 | 4,301 | BN13S71 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,843.20 | 2,912 | B5LL2C2 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $6,790.06 | 1,334 | BP81RK8 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $6,646.77 | 1,521 | BSMLR16 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $6,401.20 | 520 | BTNMG41 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $6,249.76 | 1,166 | BQ6C357 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,670.08 | 752 | B9L5200 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,607.00 | 3,738 | BKMQF66 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,429.76 | 6,464 | BPG5P75 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $5,037.12 | 2,376 | BMW5LX6 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,813.38 | 2,178 | BLBR8D5 |
| 0.01% | NKTX | NKARTA INC | -- | $4,765.45 | 2,495 | BK80YJ8 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $3,827.55 | 4,029 | BCZS820 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,390.48 | 2,216 | BFDV8K0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,149.22 | 2,157 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $2,939.20 | 1,837 | BNLYBJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,591.12 | 1,322 | BNKF6N0 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,530.81 | 2,968 | BF12XC2 |
| -- | PEPG | PEPGEN INC | -- | $2,146.76 | 1,148 | BMTX3D7 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,047.04 | 4,977 | BJL38Z1 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $1,951.68 | 856 | BMF1LJ7 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,717.56 | 1,101 | BP2TPK4 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,251.25 | 175 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,080.28 | 452 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $766.12 | 428 | BS2FKQ4 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,446,952 | -- | 3,675 | -- |
| 25.94% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 14,275,642 | -- | 3,007 | -- |
| 24.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,615,744 | -- | 2,868 | -- |
| 20.67% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 11,374,938 | -- | 2,396 | -- |
| 16.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,134,132 | -- | 1,924 | -- |
| 16.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,110,395 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,988,339.15 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $15,051,593.93 | 15,051,594 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More