BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
This fund will undergo a share split, effective prior to market open on November 19, 2026, when the fund will begin trading at its post-split price. The split will not change the total value of a shareholder’s investment. Please refer to the press release for more information specific to this fund.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.67% | 24.99% | 47.98% | 51.34% | 69.14% | 43.98% | 6.41% | 12.60% | 18.47% | 04/07/2010 |
| BIB Market Price | 4.40% | 24.85% | 47.78% | 51.20% | 68.94% | 43.92% | 6.39% | 12.57% | 18.46% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -0.91% | 14.69% | 41.74% | 44.83% | 94.28% | 35.26% | 4.58% | 9.38% | 18.26% | 04/07/2010 |
| BIB NAV | -1.01% | 14.41% | 41.46% | 44.59% | 93.99% | 35.10% | 4.57% | 9.35% | 18.24% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $103,304,423
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/12/2026- NAV
- NAV Change
- Market Price $117.41
- Market Price Change $-5.72
- Trading Volume (M) 6,088
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $103,304,423
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/12/2026- NAV
- NAV Change
- Market Price $117.41
- Market Price Change $-5.72
- Trading Volume (M) 6,088
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2027. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2026
Holdings
as of 11/12/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.70% | GILD | GILEAD SCIENCES INC | -- | $5,886,647.50 | 35,050 | 2369174 |
| 5.39% | AMGN | AMGEN INC | -- | $5,572,959.92 | 11,932 | 2023607 |
| 4.95% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,110,937.78 | 9,419 | 2931034 |
| 3.91% | REGN | REGENERON PHARMACEUTICALS | -- | $4,038,752.74 | 4,246 | 2730190 |
| 3.75% | MRNA | MODERNA INC | -- | $3,877,888.70 | 16,762 | BGSXTS3 |
| 1.54% | RVMD | REVOLUTION MEDICINES INC | -- | $1,586,973.65 | 8,999 | BL71K91 |
| 1.50% | BIIB | BIOGEN INC | -- | $1,553,977.92 | 6,204 | 2455965 |
| 1.29% | ILMN | ILLUMINA INC | -- | $1,328,547.00 | 6,340 | 2613990 |
| 1.24% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $1,284,932.09 | 18,694 | BMVP7Y0 |
| 1.17% | ROIV | ROIVANT SCIENCES LTD | -- | $1,212,776.73 | 30,327 | BMW4NZ9 |
| 1.09% | ARGX | ARGENX SE - ADR | -- | $1,124,604.18 | 1,146 | BDVLM39 |
| 1.05% | INSM | INSMED INC | -- | $1,082,465.76 | 9,168 | 2614487 |
| 1.03% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,069,144.62 | 1,802 | 2430412 |
| 1.00% | INCY | INCYTE CORP | -- | $1,035,667.00 | 8,510 | 2471950 |
| 0.96% | VTRS | VIATRIS INC | -- | $996,790.08 | 48,224 | BMWS3X9 |
| 0.85% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $880,059.70 | 5,618 | B00FWN1 |
| 0.84% | GH | GUARDANT HEALTH INC | -- | $872,481.24 | 5,634 | BFXC911 |
| 0.75% | MEDP | MEDPACE HOLDINGS INC | -- | $769,816.48 | 1,172 | BDCBC61 |
| 0.70% | EXEL | EXELIXIS INC | -- | $726,545.52 | 10,403 | 2576941 |
| 0.70% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $722,829.80 | 4,267 | 2623911 |
| 0.67% | ASND | ASCENDIS PHARMA A/S | -- | $690,375.95 | 2,585 | BWXJHM8 |
| 0.64% | BBIO | BRIDGEBIO PHARMA INC | -- | $658,035.06 | 8,418 | BK1KWG8 |
| 0.63% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $655,008.25 | 2,725 | B4Q5ZN4 |
| 0.61% | ONC | BEONE MEDICINES LTD-ADR | -- | $626,019.80 | 1,505 | BYYWPW6 |
| 0.54% | TEM | TEMPUS AI INC-CL A | -- | $558,853.96 | 7,364 | BSLSJJ0 |
| 0.49% | SMMT | SUMMIT THERAPEUTICS INC | -- | $504,906.98 | 33,493 | BMTVQS7 |
| 0.46% | HALO | HALOZYME THERAPEUTICS INC | -- | $479,793.22 | 4,766 | 2975098 |
| 0.45% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $460,800.90 | 8,127 | 2437071 |
| 0.43% | KYMR | KYMERA THERAPEUTICS INC | -- | $443,823.30 | 3,490 | BMPRZV5 |
| 0.42% | SNY | SANOFI-ADR | -- | $438,611.46 | 9,051 | 2964557 |
| 0.40% | BNTX | BIONTECH SE-ADR | -- | $413,379.44 | 4,861 | BK6H543 |
| 0.40% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $412,878.91 | 971 | BD59BS7 |
| 0.39% | PCVX | VAXCYTE INC | -- | $404,183.12 | 6,248 | BKPVGH6 |
| 0.37% | SYRE | SPYRE THERAPEUTICS INC | -- | $380,972.82 | 3,702 | BQBBDY8 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $380,618.72 | 1,172 | BQ721R4 |
| 0.37% | KRYS | KRYSTAL BIOTECH INC | -- | $379,960.24 | 1,243 | BD6JX35 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $365,110.46 | 2,717 | BDCBCD8 |
| 0.32% | ALKS | ALKERMES PLC | -- | $330,927.12 | 7,044 | B3P6D26 |
| 0.32% | CYTK | CYTOKINETICS INC | -- | $327,805.92 | 5,837 | BBBSBJ5 |
| 0.31% | TWST | TWIST BIOSCIENCE CORP | -- | $318,216.92 | 2,786 | BGKG6G7 |
| 0.31% | AXSM | AXSOME THERAPEUTICS INC | -- | $317,614.00 | 2,200 | BYZR4X4 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $317,495.40 | 2,890 | BF2YWG4 |
| 0.31% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $317,319.10 | 14,623 | BFNF1D6 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $303,953.60 | 8,672 | BJRFSB7 |
| 0.29% | TXG | 10X GENOMICS INC-CLASS A | -- | $298,277.70 | 5,047 | BKS3RS7 |
| 0.28% | ORKA | ORUKA THERAPEUTICS INC | -- | $291,872.20 | 2,780 | BKVF0J2 |
| 0.28% | KOD | KODIAK SCIENCES INC | -- | $285,563.50 | 2,638 | BFXC933 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $284,261.44 | 11,864 | BT18HP9 |
| 0.27% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $279,646.65 | 5,931 | BYQBFJ8 |
| 0.26% | IBRX | IMMUNITYBIO INC | -- | $270,090.72 | 44,496 | BNSP0B8 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $264,717.99 | 837 | 2501578 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $261,098.30 | 3,722 | BRBCSP4 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $254,510.91 | 2,727 | BJDX8Y8 |
| 0.25% | SUPN | SUPERNUS INC | -- | $254,419.60 | 8,713 | BTZRLN8 |
| 0.22% | ERAS | ERASCA INC | -- | $231,713.52 | 14,684 | BNLYBF3 |
| 0.22% | GRAL | GRAIL INC | -- | $227,652.60 | 1,876 | BSLSSX7 |
| 0.21% | PTCT | PTC THERAPEUTICS INC | -- | $222,076.80 | 3,505 | B17VCN9 |
| 0.21% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $220,677.08 | 5,113 | BFZQ0L8 |
| 0.21% | ABVX | ABIVAX SA-ADR | -- | $216,570.20 | 2,401 | BLC89B2 |
| 0.21% | COGT | COGENT BIOSCIENCES INC | -- | $212,284.90 | 7,285 | BLR6XK8 |
| 0.20% | GMAB | GENMAB A/S -SP ADR | -- | $210,633.54 | 4,071 | BBC9WC7 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $208,939.20 | 4,560 | BKY5JZ8 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $204,074.48 | 3,958 | BLFGJD5 |
| 0.19% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $197,516.00 | 6,700 | BJ5FZ74 |
| 0.19% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $195,255.84 | 2,028 | BRXB0C0 |
| 0.18% | IONS | IONIS PHARMACEUTICALS INC | -- | $190,569.18 | 6,978 | BDJ0LS6 |
| 0.18% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $186,153.00 | 5,641 | BV2DHY6 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $175,913.15 | 7,079 | BP2P6L0 |
| 0.17% | CRSP | CRISPR THERAPEUTICS AG | -- | $173,037.20 | 4,060 | BDHF4K6 |
| 0.16% | XENE | XENON PHARMACEUTICALS INC | -- | $166,685.67 | 4,066 | BRJ3GY4 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $166,336.00 | 9,200 | BN2R582 |
| 0.15% | ABCL | ABCELLERA BIOLOGICS INC | -- | $158,078.48 | 13,604 | BL53SR3 |
| 0.15% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $157,332.34 | 5,269 | BPCK358 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $148,601.56 | 3,076 | BMFD115 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $148,474.59 | 1,931 | BMH5RL1 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $145,275.81 | 5,277 | BKX9VD3 |
| 0.14% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $145,099.71 | 19,017 | BF0DMK7 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $134,166.76 | 1,612 | BMGJZJ8 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $133,341.39 | 7,839 | BN15WD1 |
| 0.13% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $131,206.62 | 7,233 | 2713317 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $127,597.48 | 4,052 | BK0VHF6 |
| 0.12% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $127,439.10 | 7,654 | BLR7H87 |
| 0.12% | DNLI | DENALI THERAPEUTICS INC | -- | $126,770.79 | 6,711 | BD2B4V0 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $124,495.72 | 9,403 | B9NSBM2 |
| 0.12% | VCEL | VERICEL CORP | -- | $123,453.00 | 2,150 | BSBMN89 |
| 0.12% | XNCR | XENCOR INC | -- | $119,041.86 | 3,122 | BGCYWN8 |
| 0.11% | MBX | MBX BIOSCIENCES INC | -- | $110,219.22 | 2,022 | BQXJKH2 |
| 0.10% | BEAM | BEAM THERAPEUTICS INC | -- | $104,194.08 | 4,336 | BK6L288 |
| 0.10% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $100,209.46 | 5,018 | BP8JSP4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $99,730.84 | 2,948 | BMZ2X38 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $90,532.85 | 5,585 | BFWLC09 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $87,846.00 | 3,025 | BL55460 |
| 0.08% | REPL | REPLIMUNE GROUP INC | -- | $86,930.90 | 3,955 | BDDVW37 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $86,100.48 | 7,104 | BK4PZ38 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $84,161.88 | 2,332 | BSRK699 |
| 0.08% | VCYT | VERACYTE INC | -- | $83,101.62 | 3,374 | BFTWZY0 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $82,607.20 | 2,444 | BKSGZN7 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $82,391.04 | 10,728 | 2100362 |
| 0.08% | SEPN | SEPTERNA INC | -- | $82,045.60 | 1,960 | BQNKXX2 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $81,474.84 | 5,982 | BJH9ZN0 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $80,099.58 | 3,993 | BRXYZ57 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $79,622.32 | 2,507 | BCBVTX1 |
| 0.08% | ZYME | ZYMEWORKS INC | -- | $78,854.13 | 2,979 | BPCQZY9 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $75,650.68 | 2,737 | BQB42H3 |
| 0.07% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $74,841.75 | 22,475 | BM9FJ13 |
| 0.07% | ETON | ETON PHARMACEUTICALS INC | -- | $73,740.00 | 1,200 | BGL0JK3 |
| 0.07% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $73,050.00 | 1,500 | BS2CR64 |
| 0.07% | QURE | UNIQURE NV | -- | $71,722.56 | 2,912 | BJFSR88 |
| 0.07% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $71,694.18 | 3,867 | BMX9K07 |
| 0.07% | PSNL | PERSONALIS INC | -- | $71,100.38 | 4,483 | BJQ0608 |
| 0.07% | SRPT | SAREPTA THERAPEUTICS INC | -- | $70,988.34 | 4,434 | B8DPDT7 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $70,949.60 | 2,708 | BJQ05Z6 |
| 0.07% | PGEN | PRECIGEN INC | -- | $70,044.46 | 15,031 | BKM5C84 |
| 0.07% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,572.90 | 965 | BCDWBX6 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $68,249.60 | 3,440 | BQS9486 |
| 0.07% | NRIX | NURIX THERAPEUTICS INC | -- | $67,953.60 | 4,356 | BMVLGP2 |
| 0.07% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $67,325.26 | 4,138 | BJ62Z18 |
| 0.06% | ALVO | ALVOTECH SA | -- | $66,309.33 | 14,199 | BPNTJ34 |
| 0.06% | ABSI | ABSCI CORP | -- | $65,808.54 | 7,204 | BN94K69 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $62,055.10 | 5,882 | BYZM6C2 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $61,034.04 | 1,674 | B3X26D8 |
| 0.06% | NVAX | NOVAVAX INC | -- | $60,654.24 | 6,924 | BJDQXG4 |
| 0.06% | ANAB | ANAPTYSBIO INC | -- | $59,425.88 | 1,244 | BDRW1L7 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,273.88 | 1,945 | BLCD809 |
| 0.06% | OCUL | OCULAR THERAPEUTIX INC | -- | $57,895.32 | 9,219 | BNZB1X8 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $57,584.38 | 13,678 | BNC1BX1 |
| 0.06% | INVA | INNOVIVA INC | -- | $57,536.01 | 3,033 | BDDXF67 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $57,520.50 | 3,711 | BP9N0G0 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $57,287.36 | 4,888 | BYSS4X4 |
| 0.05% | MNKD | MANNKIND CORP | -- | $56,155.84 | 13,499 | BF081J4 |
| 0.05% | OMER | OMEROS CORP | -- | $54,671.61 | 3,039 | B4NB858 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $54,152.28 | 2,052 | BZ7PJQ1 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $54,138.67 | 617 | BNSP8K3 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $53,269.69 | 2,881 | BP6C0S2 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $52,061.90 | 2,014 | BR3T9B6 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $51,532.95 | 1,785 | BNFWZS4 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $51,263.52 | 5,621 | BMC3HS7 |
| 0.05% | TYRA | TYRA BIOSCIENCES INC | -- | $49,511.33 | 2,505 | BMVNDH9 |
| 0.05% | ZLAB | ZAI LAB LTD-ADR | -- | $48,694.80 | 1,870 | BD9GVY0 |
| 0.05% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $48,038.40 | 6,255 | BMCWKZ2 |
| 0.05% | VOR | VOR BIOPHARMA INC | -- | $47,971.56 | 2,483 | BRJJYT3 |
| 0.04% | HROW | HARROW INC | -- | $44,544.20 | 1,574 | BHNDW86 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $44,229.00 | 1,282 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $40,714.72 | 8,626 | BYXGN81 |
| 0.04% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $39,065.40 | 1,973 | BL5B6Z1 |
| 0.04% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $37,499.22 | 3,531 | BYP80F1 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $36,983.50 | 4,351 | BKVDFF7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $35,820.96 | 784 | BQD3J33 |
| 0.03% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $35,755.92 | 3,748 | BN7Q7R7 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $35,432.49 | 4,031 | BFYQFJ2 |
| 0.03% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $34,081.70 | 1,366 | BX7RSN3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $33,639.60 | 6,936 | B3MZ6K5 |
| 0.03% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,473.18 | 8,306 | BZ0QMB7 |
| 0.03% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $33,339.11 | 3,581 | BP7KZP7 |
| 0.03% | ALMS | ALUMIS INC | -- | $33,304.29 | 5,433 | BPLQG36 |
| 0.03% | ARDX | ARDELYX INC | -- | $32,638.32 | 10,461 | BN89V40 |
| 0.03% | ANNX | ANNEXON INC | -- | $31,597.23 | 7,959 | BMVV9R5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $31,507.00 | 4,501 | BQHN6C7 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $31,382.10 | 885 | BL95N25 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $30,949.83 | 4,353 | BP81R42 |
| 0.03% | OABI | OMNIAB INC | -- | $30,209.85 | 6,103 | BN13S71 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $29,618.46 | 7,614 | BPBJFM7 |
| 0.03% | JANX | JANUX THERAPEUTICS INC | -- | $29,496.17 | 2,566 | BMFX8Y7 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,833.10 | 2,201 | BQS7491 |
| 0.03% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $28,254.05 | 2,585 | BP2NYN2 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $28,094.69 | 2,319 | BKLXFX5 |
| 0.03% | BCAX | BICARA THERAPEUTICS INC | -- | $28,075.47 | 2,777 | BQB42F1 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $27,810.72 | 2,492 | BLFBZ32 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,793.66 | 2,627 | BMFK3H6 |
| 0.03% | KURA | KURA ONCOLOGY INC | -- | $27,743.62 | 3,734 | BYZD465 |
| 0.03% | OLMA | OLEMA ONCOLOGY INC | -- | $27,620.96 | 3,673 | BMZ4LN0 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $27,523.19 | 2,701 | BM90J52 |
| 0.03% | AVBP | ARRIVENT BIOPHARMA INC | -- | $27,054.90 | 2,070 | BMGTLY5 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $26,940.29 | 3,211 | BP0TQC5 |
| 0.03% | GERN | GERON CORP | -- | $26,812.16 | 26,974 | 2370381 |
| 0.03% | WVE | WAVE LIFE SCIENCES INC | -- | $26,098.16 | 8,272 | C08GM13 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $25,708.50 | 13,050 | B4N8MH9 |
| 0.02% | SANA | SANA BIOTECHNOLOGY INC | -- | $25,259.67 | 12,567 | BMFJJ97 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $24,716.00 | 6,179 | BYV2W40 |
| 0.02% | RGNX | REGENXBIO INC | -- | $22,243.10 | 2,770 | BZ0G875 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $21,172.32 | 624 | B292NQ7 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $21,157.08 | 3,396 | BJLKVS6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $20,052.10 | 839 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $19,895.78 | 2,771 | BDRJH21 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,682.73 | 2,421 | B2Q9833 |
| 0.02% | ARVN | ARVINAS INC | -- | $18,851.28 | 2,744 | BDZ30Q0 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,810.33 | 5,269 | BYVQJ96 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $18,696.93 | 2,254 | BP7L561 |
| 0.02% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,659.88 | 9,147 | BYWVTY5 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $17,727.42 | 2,154 | B91XRN2 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,501.28 | 2,166 | B7F2TY6 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $17,252.80 | 820 | BPBPCG8 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $16,077.92 | 1,028 | BTNMG41 |
| 0.02% | SPRY | ARS PHARMACEUTICALS INC | -- | $15,906.75 | 4,175 | BMCR7V2 |
| 0.02% | CRMD | CORMEDIX INC | -- | $15,831.64 | 3,271 | BJ0LT31 |
| 0.02% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $15,516.45 | 2,523 | BPRB2N7 |
| 0.01% | PEPG | PEPGEN INC | -- | $14,656.32 | 2,908 | BMTX3D7 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $14,304.28 | 5,164 | BKX9NQ0 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,175.07 | 3,367 | BLN9Z50 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $13,796.58 | 6,447 | BZ8FPH3 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,686.40 | 1,222 | B9L5200 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,515.96 | 1,382 | BPRBTY7 |
| 0.01% | ALT | ALTIMMUNE INC | -- | $13,147.26 | 8,166 | BFY7DC4 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $13,057.88 | 2,596 | BSMLR16 |
| 0.01% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $11,994.81 | 14,504 | BFZNYB7 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $11,783.36 | 3,202 | BJDX8Z9 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $11,774.70 | 4,361 | BMXNGZ6 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,015.51 | 4,609 | BDFKQ07 |
| 0.01% | BIOA | BIOAGE LABS INC | -- | $10,876.25 | 1,925 | BT9K6D8 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,189.44 | 8,352 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $10,163.20 | 1,588 | 2517058 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,060.48 | 1,192 | BKC9SX3 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $10,025.10 | 2,538 | B12W3P6 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $10,022.04 | 3,444 | BQ6C357 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,020.99 | 8,421 | BFMLGR4 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,964.05 | 2,715 | BMVBZF5 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $9,465.61 | 7,117 | BK5MWR1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,142.08 | 4,272 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $8,716.24 | 3,016 | 2107437 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,447.78 | 1,634 | BP81RK8 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $8,386.56 | 832 | BM7V485 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,019.77 | 12,374 | BM8NHS1 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,943.55 | 11,662 | BMYTJP4 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,765.45 | 1,961 | BKDQKM6 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $6,575.14 | 2,299 | BRCFFK6 |
| 0.01% | SION | SIONNA THERAPEUTICS INC | -- | $6,506.71 | 1,897 | BQKXDX4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,533.16 | 3,502 | BLBR8D5 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $5,390.62 | 1,318 | BQV0J03 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,360.88 | 3,191 | BPTK6Z2 |
| -- | FHTX | FOGHORN THERAPEUTICS INC | -- | $5,108.60 | 2,492 | BMF7DT9 |
| -- | CDXS | CODEXIS INC | -- | $4,403.43 | 4,596 | B5LL2C2 |
| -- | VYGR | VOYAGER THERAPEUTICS INC | -- | $4,396.20 | 2,586 | BY7RB53 |
| -- | NBP | NOVABRIDGE BIOSCIENCES | -- | $3,910.96 | 4,712 | BKRRKY7 |
| -- | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $3,850.74 | 3,892 | BYTYP72 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,664.72 | 2,411 | BKTV702 |
| -- | CHRS | COHERUS ONCOLOGY INC | -- | $3,492.71 | 6,486 | BRK0149 |
| -- | NMRA | NEUMORA THERAPEUTICS INC | -- | $3,415.50 | 7,888 | BN4JN37 |
| -- | TNYA | TENAYA THERAPEUTICS INC | -- | $3,270.67 | 9,412 | BNNXX52 |
| -- | GOSS | GOSSAMER BIO INC | -- | $2,877.44 | 256 | C0BCTT5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,544.59 | 4,845 | BNNXX18 |
| -- | CRBU | CARIBOU BIOSCIENCES INC | -- | $1,710.52 | 4,499 | BNYJR68 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $1,395.36 | 918 | BTXQTX3 |
| -- | EYPT | EYEPOINT INC | -- | $1,155.95 | 3,618 | BMGS7L1 |
| -- | -- | COHERUS ONCOLOGY INC COMMON STOCK USD | -- | $00.00 | 5,356 | -- |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 30.79% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 31,802,249 | -- | 4,388 | -- |
| 30.57% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 31,584,823 | -- | 4,358 | -- |
| 29.54% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,519,433 | -- | 4,211 | -- |
| 18.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 19,126,284 | -- | 2,639 | -- |
| 17.63% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 18,213,093 | -- | 2,513 | -- |
| 9.89% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 10,211,798 | -- | 1,409 | -- |
| -- | IQMM | PROSHARES GENIUS MONEY MARKET ETF | -- | $17,017,000.00 | 170,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,132,037.58 | 21,132,038 | -- |
Index
as of 9/30/2026
- Total Number of Holdings245
- Price/Book Ratio6.08
- Dividend Yield ( % )0.49
- Avg. Index Market Capitalization$7.91 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: Why hedge?—A tool for managing risk
Periods of uncertainty often make investors want to reduce risk in their portfolios. A hedging strategy may help investors manage risk while remaining invested for long-term growth.
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