BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View fund details
Documents & Downloads
ETF & Index
Prospectus & Regulatory
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 12/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/15/2026- NAV $80.87
- NAV Change $-2.34
- Market Price $80.81
- Market Price Change $-2.37
- Trading Volume (M) 9,802
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/15/2026- NAV $80.87
- NAV Change $-2.34
- Market Price $80.81
- Market Price Change $-2.37
- Trading Volume (M) 9,802
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 1/15/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.75% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,930,388.36 | 11,233 | 2931034 |
| 5.47% | GILD | GILEAD SCIENCES INC | -- | $4,691,791.92 | 38,692 | 2369174 |
| 5.43% | AMGN | AMGEN INC | -- | $4,652,102.88 | 14,096 | 2023607 |
| 4.00% | REGN | REGENERON PHARMACEUTICALS | -- | $3,430,638.08 | 4,624 | 2730190 |
| 2.87% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $2,456,992.59 | 26,141 | 2989044 |
| 2.48% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,125,022.90 | 5,915 | B00FWN1 |
| 1.77% | INSM | INSMED INC | -- | $1,520,869.23 | 9,549 | 2614487 |
| 1.29% | BIIB | BIOGEN INC | -- | $1,107,336.33 | 6,569 | 2455965 |
| 1.24% | RVMD | REVOLUTION MEDICINES INC | -- | $1,067,025.12 | 8,656 | BL71K91 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $1,060,464.96 | 1,304 | BDVLM39 |
| 1.16% | ILMN | ILLUMINA INC | -- | $993,997.30 | 6,841 | 2613990 |
| 1.08% | INCY | INCYTE CORP | -- | $925,059.60 | 8,790 | 2471950 |
| 1.06% | UTHR | UNITED THERAPEUTICS CORP | -- | $909,996.72 | 1,928 | 2430412 |
| 0.91% | MEDP | MEDPACE HOLDINGS INC | -- | $779,348.44 | 1,261 | BDCBC61 |
| 0.89% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $759,803.88 | 19,129 | BMVP7Y0 |
| 0.85% | ROIV | ROIVANT SCIENCES LTD | -- | $725,538.70 | 31,139 | BMW4NZ9 |
| 0.80% | MRNA | MODERNA INC | -- | $688,288.32 | 17,487 | BGSXTS3 |
| 0.77% | VTRS | VIATRIS INC | -- | $661,876.32 | 51,548 | BMWS3X9 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $657,971.28 | 8,628 | BK1KWG8 |
| 0.76% | GH | GUARDANT HEALTH INC | -- | $648,588.16 | 5,792 | BFXC911 |
| 0.69% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $595,274.40 | 4,464 | 2623911 |
| 0.69% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $591,144.96 | 2,749 | BV9G6B8 |
| 0.67% | SMMT | SUMMIT THERAPEUTICS INC | -- | $575,626.37 | 33,331 | BMTVQS7 |
| 0.66% | SNY | SANOFI-ADR | -- | $562,424.56 | 11,848 | 2964557 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $559,926.92 | 7,252 | BDJ0LS6 |
| 0.64% | EXEL | EXELIXIS INC | -- | $545,461.76 | 12,004 | 2576941 |
| 0.62% | TEM | TEMPUS AI INC | -- | $533,371.88 | 7,739 | BSLSJJ0 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $504,309.96 | 1,017 | BD59BS7 |
| 0.57% | RNA | AVIDITY BIOSCIENCES INC | -- | $489,759.60 | 6,746 | BMWHPY1 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $479,966.75 | 4,525 | BK6H543 |
| 0.56% | ONC | BEONE MEDICINES LTD-ADR | -- | $476,650.61 | 1,409 | BYYWPW6 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $473,216.51 | 8,593 | 2437071 |
| 0.54% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $465,726.36 | 2,721 | B4Q5ZN4 |
| 0.47% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $402,866.25 | 6,081 | BYQBFJ8 |
| 0.46% | AXSM | AXSOME THERAPEUTICS INC | -- | $393,033.98 | 2,257 | BYZR4X4 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $378,132.30 | 5,265 | 2975098 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $367,098.35 | 5,787 | BBBSBJ5 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $366,330.99 | 1,299 | BD6JX35 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $343,321.44 | 3,234 | BMVBZD3 |
| 0.40% | CAI | CARIS LIFE SCIENCES INC | -- | $342,579.84 | 12,632 | BT18HP9 |
| 0.39% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $333,468.80 | 1,120 | BQ721R4 |
| 0.37% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $316,907.28 | 2,988 | BF2YWG4 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $308,702.40 | 2,643 | BLC89B2 |
| 0.33% | PCVX | VAXCYTE INC | -- | $281,754.60 | 5,865 | BKPVGH6 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $271,850.16 | 3,594 | B17VCN9 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $269,647.50 | 6,870 | BLR6XK8 |
| 0.30% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $254,804.94 | 2,997 | BQS9486 |
| 0.28% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $239,714.64 | 4,248 | BDD19F8 |
| 0.28% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $237,215.25 | 2,799 | BDCBCD8 |
| 0.27% | ALKS | ALKERMES PLC | -- | $230,903.12 | 7,396 | B3P6D26 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $230,880.39 | 4,259 | BDHF4K6 |
| 0.27% | KYMR | KYMERA THERAPEUTICS INC | -- | $229,077.52 | 3,221 | BMPRZV5 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $212,549.04 | 4,568 | BFZQ0L8 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $212,428.32 | 2,301 | BJDX8Y8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $203,996.00 | 7,846 | BJRFSB7 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $200,964.75 | 7,575 | 2713317 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $198,241.25 | 2,455 | BM9HHL5 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $197,678.34 | 13,814 | B19FQ48 |
| 0.22% | CGON | CG ONCOLOGY INC | -- | $191,476.56 | 3,608 | BRBCSP4 |
| 0.22% | ADMA | ADMA BIOLOGICS INC | -- | $186,480.00 | 10,656 | B9NSBM2 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $185,583.30 | 14,070 | BFNF1D6 |
| 0.21% | INDV | INDIVIOR PLC | -- | $183,827.15 | 5,590 | BP0BQQ5 |
| 0.21% | ACLX | ARCELLX INC | -- | $176,880.48 | 2,589 | BPCJ1Q2 |
| 0.20% | IBRX | IMMUNITYBIO INC | -- | $174,195.00 | 44,100 | BNSP0B8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $172,746.48 | 881 | 2501578 |
| 0.20% | GRAL | GRAIL INC | -- | $170,130.24 | 1,746 | BSLSSX7 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $161,569.08 | 5,076 | BP8JSP4 |
| 0.17% | TERN | TERNS PHARMACEUTICALS INC | -- | $149,140.34 | 4,033 | BMDJ0C9 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $145,603.15 | 4,543 | BK6L288 |
| 0.17% | VCYT | VERACYTE INC | -- | $145,345.00 | 3,545 | BFTWZY0 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $144,558.24 | 5,484 | BKX9VD3 |
| 0.17% | IDYA | IDEAYA BIOSCIENCES INC | -- | $141,535.50 | 3,925 | BK0VHF6 |
| 0.16% | XENE | XENON PHARMACEUTICALS INC | -- | $140,960.40 | 3,460 | BRJ3GY4 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $140,008.65 | 1,901 | BMH5RL1 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $132,499.64 | 2,863 | BL55460 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $129,067.68 | 2,568 | B72ZBG4 |
| 0.15% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $126,084.00 | 4,740 | BKY5JZ8 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $123,328.26 | 6,567 | BD2B4V0 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $121,526.30 | 6,835 | BJ5FZ74 |
| 0.14% | ERAS | ERASCA INC | -- | $121,431.12 | 12,702 | BNLYBF3 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $120,057.60 | 1,690 | BMGJZJ8 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $116,281.92 | 5,664 | BYTQ6X1 |
| 0.13% | SYRE | SPYRE THERAPEUTICS INC | -- | $114,954.66 | 3,474 | BQBBDY8 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $113,770.40 | 4,006 | BLFGJD5 |
| 0.13% | TWST | TWIST BIOSCIENCE CORP | -- | $112,914.72 | 2,736 | BGKG6G7 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $111,210.72 | 3,544 | BP9N0G0 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $110,579.20 | 5,216 | BKS3RS7 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $107,554.80 | 9,535 | BNZB1X8 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $106,822.08 | 23,022 | BM9FJ13 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $105,313.95 | 7,485 | BYZG9R0 |
| 0.12% | ALMS | ALUMIS INC | -- | $105,212.01 | 4,353 | BPLQG36 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $104,989.48 | 6,394 | BN15WD1 |
| 0.12% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $102,807.18 | 3,522 | BMZ4LN0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $101,496.50 | 4,319 | BJ62Z18 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $99,730.80 | 4,680 | B8DPDT7 |
| 0.11% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $96,745.60 | 4,319 | BLB0YQ9 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $93,901.39 | 2,579 | BKSGZN7 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $88,585.45 | 2,617 | BBC9WC7 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $87,777.61 | 5,903 | BFWLC09 |
| 0.10% | VCEL | VERICEL CORP | -- | $87,361.05 | 2,265 | BSBMN89 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $85,801.74 | 1,006 | BCDWBX6 |
| 0.10% | MAZE | MAZE THERAPEUTICS INC | -- | $85,750.74 | 2,154 | BSRK699 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $85,586.68 | 4,538 | BMVLGP2 |
| 0.10% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $83,354.70 | 3,770 | BMX9K07 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $82,229.10 | 2,010 | BQXJKH2 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $82,129.96 | 5,258 | BRJZSK0 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $80,426.97 | 3,891 | BN7Q7R7 |
| 0.09% | HROW | HARROW INC | -- | $80,396.42 | 1,658 | BHNDW86 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $79,160.50 | 3,350 | BPCQZY9 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $77,622.30 | 1,998 | BQKXDX4 |
| 0.09% | MNKD | MANNKIND CORP | -- | $76,713.84 | 13,748 | BF081J4 |
| 0.09% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $76,674.24 | 2,022 | BRXB0C0 |
| 0.09% | ARDX | ARDELYX INC | -- | $76,588.16 | 10,879 | BN89V40 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $74,868.96 | 2,557 | BJQ05Z6 |
| 0.09% | UPB | UPSTREAM BIO INC | -- | $74,778.00 | 2,420 | BRCFFK6 |
| 0.09% | PHVS | PHARVARIS NV | -- | $73,564.20 | 2,868 | BMZ2X38 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $72,585.80 | 2,611 | BCBVTX1 |
| 0.08% | TNGX | TANGO THERAPEUTICS INC | -- | $70,490.70 | 6,030 | BP2P6L0 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $70,427.50 | 2,167 | BKVF0J2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $70,193.20 | 2,915 | BP7KZP7 |
| 0.08% | ALVO | ALVOTECH SA | -- | $69,374.25 | 14,015 | BPNTJ34 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $69,328.78 | 2,389 | BMVNDH9 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $69,193.20 | 5,014 | BYSS4X4 |
| 0.08% | -- | DEFINIUM THERAPEUTICS INC COMMON STOCK USD 0 | -- | $67,825.80 | 4,410 | -- |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $67,584.42 | 9,426 | 2100362 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $66,876.69 | 2,657 | BMFD115 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $66,477.84 | 4,917 | BPCK358 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,363.50 | 1,415 | BX7RSN3 |
| 0.08% | INVA | INNOVIVA INC | -- | $66,156.48 | 3,348 | BDDXF67 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $66,026.52 | 4,137 | BRXYZ57 |
| 0.08% | PGEN | PRECIGEN INC | -- | $65,440.98 | 15,807 | BKM5C84 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $63,960.75 | 1,953 | BLCD809 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $63,412.50 | 2,375 | BFXC933 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $61,773.16 | 5,741 | BJH9ZN0 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $61,498.47 | 5,181 | BYZM6C2 |
| 0.07% | QURE | UNIQURE NV | -- | $61,302.22 | 2,789 | BJFSR88 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $60,328.31 | 16,261 | BWJDYK1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $60,093.60 | 12,264 | BNC1BX1 |
| 0.07% | RLAY | RELAY THERAPEUTICS INC | -- | $59,208.80 | 7,760 | BN2R582 |
| 0.07% | EYPT | EYEPOINT INC | -- | $58,718.88 | 3,707 | BMGS7L1 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $57,424.40 | 1,240 | BDRW1L7 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $57,372.96 | 2,136 | BR3T9B6 |
| 0.07% | NVAX | NOVAVAX INC | -- | $56,599.50 | 7,275 | BJDQXG4 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $56,099.78 | 13,421 | BL53SR3 |
| 0.06% | SANA | SANA BIOTECHNOLOGY INC | -- | $55,694.42 | 11,926 | BMFJJ97 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $55,048.89 | 7,429 | BLR7H87 |
| 0.06% | SEPN | SEPTERNA INC | -- | $54,896.90 | 2,005 | BQNKXX2 |
| 0.06% | SVRA | SAVARA INC | -- | $53,566.80 | 9,110 | BYXGN81 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $53,508.00 | 2,058 | BNFWZS4 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $53,260.25 | 1,307 | BKLCWZ3 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $50,238.72 | 4,361 | BKVDFF7 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $49,084.34 | 4,426 | BMCR7V2 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $48,775.66 | 5,462 | B8K7T65 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $47,995.50 | 4,571 | BLB0YH0 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $47,891.79 | 2,403 | BQB42H3 |
| 0.06% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $47,711.30 | 3,185 | BJLKVS6 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $47,097.92 | 2,777 | BP6C0S2 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $46,741.80 | 651 | BNSP8K3 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $45,649.70 | 2,270 | BMNDK09 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $44,282.70 | 3,195 | BMG99Y1 |
| 0.05% | XNCR | XENCOR INC | -- | $42,232.37 | 3,197 | BGCYWN8 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $40,955.84 | 2,096 | BZ7PJQ1 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $40,940.57 | 2,453 | BQB42F1 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $40,471.70 | 8,611 | BZ0QMB7 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $40,471.20 | 1,848 | BMGTLY5 |
| 0.05% | RAPT | RAPT THERAPEUTICS INC | -- | $39,947.79 | 1,241 | BTJZB49 |
| 0.05% | ANNX | ANNEXON INC | -- | $39,916.80 | 6,480 | BMVV9R5 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $39,771.90 | 1,926 | B3X26D8 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $39,458.28 | 17,774 | BF0DMK7 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,935.08 | 2,196 | BQS7491 |
| 0.05% | OMER | OMEROS CORP | -- | $38,766.75 | 3,175 | B4NB858 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $38,619.80 | 6,229 | BK4PZ38 |
| 0.04% | PSNL | PERSONALIS INC | -- | $38,170.92 | 3,972 | BJQ0608 |
| 0.04% | GERN | GERON CORP | -- | $37,156.60 | 28,582 | 2370381 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $36,947.96 | 2,693 | BMFX8Y7 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $36,654.90 | 915 | BL95N25 |
| 0.04% | ARVN | ARVINAS INC | -- | $34,885.88 | 2,876 | BDZ30Q0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,650.99 | 3,889 | BYZD465 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $34,545.06 | 1,606 | BT9K6D8 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $33,869.44 | 2,264 | BD06CS0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $33,500.39 | 10,703 | BBNBTD2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,991.46 | 1,753 | BD9GVY0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $32,919.16 | 7,283 | B3MZ6K5 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $32,247.18 | 8,082 | BPBJFM7 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,240.50 | 7,586 | BYWVTY5 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $31,764.95 | 13,517 | B4N8MH9 |
| 0.04% | RGNX | REGENXBIO INC | -- | $31,193.92 | 2,267 | BZ0G875 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $30,840.89 | 4,219 | BMC3HS7 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $30,715.14 | 813 | BQD3J33 |
| 0.04% | IVVD | INVIVYD INC | -- | $30,273.08 | 12,407 | BM8NHS1 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $28,195.70 | 2,645 | BM90J52 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,714.76 | 3,604 | BFYQFJ2 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $26,270.64 | 1,364 | BM7V485 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $25,637.60 | 3,512 | BDDVW37 |
| 0.03% | LENZ | LENZ THERAPEUTICS INC | -- | $25,414.14 | 1,401 | BQV0J03 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $25,389.35 | 10,363 | BJ0CK86 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $25,150.74 | 2,423 | BJDX8Z9 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,731.28 | 3,528 | BJ0LT31 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $24,510.00 | 3,268 | BQ6C357 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,962.86 | 6,494 | BMCWKZ2 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $23,876.16 | 3,344 | BYP80F1 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,868.00 | 2,550 | BMFK3H6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,739.42 | 2,521 | BLFBZ32 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,325.86 | 2,411 | B91XRN2 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,051.44 | 648 | B292NQ7 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,783.50 | 950 | BTNMG41 |
| 0.02% | KMDA | KAMADA LTD | -- | $21,232.26 | 2,583 | B2Q9833 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,191.66 | 3,206 | 2107437 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,535.65 | 6,733 | BN94K69 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $19,809.28 | 4,672 | BFY7DC4 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $19,742.08 | 3,488 | BQHN6C7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $19,712.70 | 2,646 | B12W3P6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,473.99 | 2,559 | BKLXFX5 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $19,400.00 | 4,000 | BYTYP72 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $18,513.02 | 1,711 | BP81RK8 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $18,507.41 | 1,201 | BGL0JK3 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,246.42 | 5,463 | BYVQJ96 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,974.95 | 4,845 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,248.20 | 1,292 | B9L5200 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,134.80 | 1,965 | BSMLR16 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $17,037.30 | 4,655 | BKRRKY7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,349.38 | 838 | BPBPCG8 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $16,320.48 | 4,496 | BZC0D70 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,199.82 | 10,062 | BFZNYB7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,934.53 | 7,481 | BN4JN37 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,900.96 | 2,532 | BMF7DT9 |
| 0.02% | PEPG | PEPGEN INC | -- | $15,364.21 | 3,079 | BMTX3D7 |
| 0.02% | AARD | AARDVARK THERAPEUTICS INC | -- | $14,966.25 | 975 | BTXQTX3 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $14,600.52 | 2,458 | BP0TQC5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,527.73 | 2,843 | BP81R42 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,510.00 | 2,902 | BDRJH21 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,393.28 | 2,256 | B7F2TY6 |
| 0.02% | LFCR | LIFECORE BIOMEDICAL INC | -- | $13,591.80 | 1,678 | 2517058 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,414.24 | 2,891 | BMVBZF5 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $13,405.84 | 2,072 | BKDQKM6 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $12,952.17 | 4,851 | BYV2W40 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,932.64 | 8,981 | BFMLGR4 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,515.58 | 693 | BS2F741 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,492.32 | 3,832 | BMXNGZ6 |
| 0.01% | OABI | OMNIAB INC | -- | $12,374.40 | 6,445 | BN13S71 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,242.56 | 1,034 | BPRBTY7 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,033.12 | 3,498 | BLN9Z50 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $11,777.84 | 3,404 | BPTK6Z2 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,687.12 | 2,102 | BL5B6Z1 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,768.65 | 8,755 | BNR5QT9 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,601.24 | 754 | BRJJYT3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,541.76 | 2,528 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,092.44 | 2,642 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,679.92 | 1,272 | BKC9SX3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,634.80 | 4,340 | BKX9NQ0 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,223.50 | 8,385 | BMYTJP4 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,135.39 | 4,371 | BZ8FPH3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,983.92 | 5,412 | BRK0149 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $8,964.80 | 4,310 | BK5MWR1 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,865.20 | 2,396 | BP7L561 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,688.88 | 1,388 | BP2NYN2 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,200.10 | 4,045 | B5LL2C2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,811.17 | 2,551 | BKTV702 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,527.04 | 4,184 | BNYJR68 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,070.13 | 4,367 | BNNXX18 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,495.08 | 7,455 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,129.92 | 2,788 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $13.07 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 38.93% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 33,377,288 | -- | 5,795 | -- |
| 30.44% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,097,065 | -- | 4,531 | -- |
| 24.03% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,602,340 | -- | 3,577 | -- |
| 16.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,307,020 | -- | 2,484 | -- |
| 15.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 13,241,481 | -- | 2,299 | -- |
| 4.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,645,871 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,486,047.43 | 25,486,047 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More