BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,401,647
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/19/2026- NAV
- NAV Change
- Market Price $77.30
- Market Price Change $+0.04
- Trading Volume (M) 4,318
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,401,647
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/19/2026- NAV
- NAV Change
- Market Price $77.30
- Market Price Change $+0.04
- Trading Volume (M) 4,318
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/19/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.95% | GILD | GILEAD SCIENCES INC | -- | $3,333,231.00 | 25,542 | 2369174 |
| 4.94% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,325,511.67 | 7,657 | 2931034 |
| 4.82% | AMGN | AMGEN INC | -- | $3,242,342.25 | 9,803 | 2023607 |
| 3.59% | REGN | REGENERON PHARMACEUTICALS | -- | $2,416,742.40 | 3,840 | 2730190 |
| 2.14% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,443,247.20 | 4,904 | B00FWN1 |
| 1.60% | RVMD | REVOLUTION MEDICINES INC | -- | $1,079,119.80 | 7,326 | BL71K91 |
| 1.54% | BIIB | BIOGEN INC | -- | $1,033,788.00 | 5,425 | 2455965 |
| 1.36% | UTHR | UNITED THERAPEUTICS CORP | -- | $918,216.00 | 1,620 | 2430412 |
| 1.27% | INSM | INSMED INC | -- | $855,842.88 | 7,968 | 2614487 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $837,658.50 | 1,050 | BDVLM39 |
| 1.23% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $830,017.17 | 15,837 | BMVP7Y0 |
| 1.19% | ILMN | ILLUMINA INC | -- | $800,917.04 | 5,653 | 2613990 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $746,436.60 | 26,460 | BMW4NZ9 |
| 1.05% | INCY | INCYTE CORP | -- | $703,520.40 | 7,359 | 2471950 |
| 1.02% | VTRS | VIATRIS INC | -- | $688,276.05 | 42,565 | BMWS3X9 |
| 0.99% | MRNA | MODERNA INC | -- | $667,512.00 | 14,600 | BGSXTS3 |
| 0.85% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $572,984.32 | 3,712 | 2623911 |
| 0.80% | ASND | ASCENDIS PHARMA A/S | -- | $541,642.48 | 2,276 | BWXJHM8 |
| 0.80% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $540,198.75 | 2,275 | B4Q5ZN4 |
| 0.71% | GH | GUARDANT HEALTH INC | -- | $476,221.50 | 4,850 | BFXC911 |
| 0.70% | BBIO | BRIDGEBIO PHARMA INC | -- | $473,022.00 | 7,167 | BK1KWG8 |
| 0.69% | EXEL | EXELIXIS INC | -- | $467,232.00 | 9,600 | 2576941 |
| 0.68% | SMMT | SUMMIT THERAPEUTICS INC | -- | $454,324.40 | 28,664 | BMTVQS7 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $451,088.56 | 6,109 | BDJ0LS6 |
| 0.66% | MEDP | MEDPACE HOLDINGS INC | -- | $441,325.41 | 1,051 | BDCBC61 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $433,511.54 | 847 | BD59BS7 |
| 0.64% | AXSM | AXSOME THERAPEUTICS INC | -- | $428,406.30 | 1,890 | BYZR4X4 |
| 0.59% | SNY | SANOFI-ADR | -- | $393,996.85 | 9,047 | 2964557 |
| 0.56% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $378,926.04 | 5,178 | BYQBFJ8 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $369,859.27 | 4,213 | BK6H543 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $354,149.10 | 7,110 | 2437071 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $350,768.81 | 1,181 | BYYWPW6 |
| 0.52% | CYTK | CYTOKINETICS INC | -- | $348,076.85 | 4,553 | BBBSBJ5 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $329,907.69 | 1,029 | BQ721R4 |
| 0.47% | KRYS | KRYSTAL BIOTECH INC | -- | $316,764.00 | 1,080 | BD6JX35 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $299,937.72 | 4,364 | 2975098 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $294,942.08 | 38,008 | BNSP0B8 |
| 0.43% | TEM | TEMPUS AI INC-CL A | -- | $292,484.72 | 6,424 | BSLSJJ0 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $273,205.00 | 2,705 | BMVBZD3 |
| 0.39% | PCVX | VAXCYTE INC | -- | $259,558.38 | 5,321 | BKPVGH6 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $258,280.83 | 2,271 | BLC89B2 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $235,748.38 | 3,017 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $232,251.57 | 2,361 | BDCBCD8 |
| 0.34% | ALKS | ALKERMES PLC | -- | $228,031.00 | 6,163 | B3P6D26 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $220,292.46 | 2,526 | BF2YWG4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $215,289.22 | 3,062 | B17VCN9 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $213,395.15 | 2,231 | BJDX8Y8 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $197,779.67 | 7,523 | BJRFSB7 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $197,685.90 | 3,123 | BRBCSP4 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $193,531.10 | 2,905 | BQBBDY8 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $187,562.50 | 6,002 | BLR6XK8 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $179,443.88 | 3,773 | BFZQ0L8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,593.10 | 4,423 | BLB0YQ9 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,041.76 | 4,624 | BTZRLN8 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $168,944.50 | 3,550 | BDHF4K6 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $166,149.70 | 3,074 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $158,731.56 | 2,028 | BM9HHL5 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $156,047.76 | 10,431 | BT18HP9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $152,926.08 | 736 | 2501578 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $144,064.34 | 3,409 | BLFGJD5 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $143,377.44 | 4,252 | BP8JSP4 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $137,373.92 | 11,632 | BFNF1D6 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $135,287.68 | 3,872 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $129,085.44 | 6,303 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $124,651.38 | 3,966 | BKY5JZ8 |
| 0.18% | VCYT | VERACYTE INC | -- | $122,485.22 | 2,938 | BFTWZY0 |
| 0.18% | ERAS | ERASCA INC | -- | $118,102.08 | 11,444 | BNLYBF3 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $112,167.00 | 2,266 | BGKG6G7 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $106,178.93 | 5,863 | BD2B4V0 |
| 0.15% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $103,334.40 | 2,880 | BQS9486 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $102,867.50 | 1,789 | BKVF0J2 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $101,053.40 | 4,978 | BP2P6L0 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $100,954.40 | 2,120 | B72ZBG4 |
| 0.15% | ALMS | ALUMIS INC | -- | $100,607.85 | 4,674 | BPLQG36 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $99,185.11 | 3,767 | BK6L288 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $96,983.79 | 4,351 | BKS3RS7 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $96,905.04 | 6,087 | BN15WD1 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $96,409.17 | 1,573 | BMH5RL1 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $91,926.72 | 3,246 | BK0VHF6 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $90,571.32 | 1,698 | BRXB0C0 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $90,402.77 | 1,411 | BMGJZJ8 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $89,446.50 | 4,587 | BKX9VD3 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $88,213.32 | 2,196 | BMFD115 |
| 0.13% | GRAL | GRAIL INC | -- | $87,764.61 | 1,439 | BSLSSX7 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $87,647.00 | 2,636 | BL55460 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $84,106.68 | 3,122 | BMX9K07 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $81,306.67 | 9,271 | 2100362 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $80,168.95 | 3,571 | BJ62Z18 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $79,734.42 | 6,606 | BN2R582 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $77,617.10 | 2,255 | BFXC933 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $76,412.70 | 4,914 | BFWLC09 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $76,137.75 | 2,925 | BP9N0G0 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $75,987.15 | 8,805 | B9NSBM2 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $73,773.70 | 3,685 | BV2DHY6 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $73,768.32 | 5,692 | BJ5FZ74 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $71,595.09 | 4,209 | BYSS4X4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $68,524.65 | 2,367 | BMZ2X38 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $67,490.40 | 2,766 | BPCQZY9 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $66,681.72 | 1,974 | BMVNDH9 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $66,665.60 | 830 | BCDWBX6 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,141.60 | 2,140 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $64,668.75 | 1,875 | BSBMN89 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $64,480.00 | 3,875 | B8DPDT7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $64,311.51 | 8,049 | BNZB1X8 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $63,245.56 | 2,111 | BJQ05Z6 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $63,132.96 | 3,261 | BN7Q7R7 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $62,784.08 | 4,742 | BJH9ZN0 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $62,209.68 | 1,651 | BQKXDX4 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $61,144.71 | 1,023 | BDRW1L7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $61,092.72 | 2,379 | BBC9WC7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $60,628.68 | 1,764 | BR3T9B6 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $60,063.18 | 2,166 | BCBVTX1 |
| 0.09% | INVA | INNOVIVA INC | -- | $59,540.20 | 2,740 | BDDXF67 |
| 0.09% | INBX | INHIBRX BIOSCIENCES INC | -- | $58,806.87 | 537 | BNSP8K3 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $57,942.48 | 3,802 | BMVLGP2 |
| 0.08% | QURE | UNIQURE NV | -- | $56,910.45 | 2,305 | BJFSR88 |
| 0.08% | ARDX | ARDELYX INC | -- | $55,211.94 | 9,066 | BN89V40 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $54,996.45 | 19,297 | BM9FJ13 |
| 0.08% | PGEN | PRECIGEN INC | -- | $54,412.80 | 13,080 | BKM5C84 |
| 0.08% | NVAX | NOVAVAX INC | -- | $53,604.70 | 6,023 | BJDQXG4 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $53,178.84 | 13,429 | BWJDYK1 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $52,702.72 | 15,232 | BF0DMK7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $52,513.68 | 10,128 | BNC1BX1 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $52,165.86 | 4,369 | BYZM6C2 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $51,711.66 | 4,059 | BPCK358 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $50,386.62 | 1,658 | BQXJKH2 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $50,330.36 | 2,294 | BP6C0S2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,059.90 | 1,870 | BD06CS0 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $49,559.30 | 5,810 | BK4PZ38 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $49,540.44 | 2,818 | BP7KZP7 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $48,889.80 | 1,730 | BZ7PJQ1 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $47,368.05 | 3,455 | BRXYZ57 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $46,930.29 | 2,343 | BQB42F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,895.53 | 1,621 | BLCD809 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $45,396.45 | 11,209 | BL53SR3 |
| 0.07% | SEPN | SEPTERNA INC | -- | $43,927.07 | 1,657 | BQNKXX2 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $43,489.88 | 1,778 | BSRK699 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $42,734.40 | 6,960 | BYZG9R0 |
| 0.06% | HROW | HARROW INC | -- | $42,031.60 | 1,370 | BHNDW86 |
| 0.06% | ALVO | ALVOTECH SA | -- | $40,048.80 | 12,210 | BPNTJ34 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $39,931.05 | 1,527 | BMGTLY5 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,402.64 | 1,172 | BX7RSN3 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $38,802.20 | 2,962 | BMZ4LN0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $36,313.28 | 6,134 | BLR7H87 |
| 0.05% | EYPT | EYEPOINT INC | -- | $36,192.84 | 3,062 | BMGS7L1 |
| 0.05% | SVRA | SAVARA INC | -- | $35,513.28 | 7,524 | BYXGN81 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $35,376.72 | 1,983 | BQB42H3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $35,358.40 | 4,510 | B8K7T65 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,121.00 | 3,054 | BYP80F1 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $35,114.09 | 3,487 | BMC3HS7 |
| 0.05% | MNKD | MANNKIND CORP | -- | $33,711.44 | 11,389 | BF081J4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,353.45 | 1,495 | B3X26D8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $33,196.80 | 2,912 | BJLKVS6 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $32,626.88 | 992 | BGL0JK3 |
| 0.05% | OMER | OMEROS CORP | -- | $31,385.34 | 2,622 | B4NB858 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $31,086.31 | 2,251 | BMFX8Y7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,972.38 | 2,185 | BM90J52 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,468.75 | 1,875 | BMNDK09 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,137.94 | 9,849 | BMFJJ97 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $29,884.14 | 1,677 | BNFWZS4 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $29,862.00 | 7,110 | BZ0QMB7 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $29,576.67 | 3,711 | BKVDFF7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,833.28 | 3,218 | BYZD465 |
| 0.04% | GERN | GERON CORP | -- | $28,794.44 | 23,602 | 2370381 |
| 0.04% | XNCR | XENCOR INC | -- | $28,221.51 | 2,711 | BGCYWN8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,139.70 | 1,934 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | PSNL | PERSONALIS INC | -- | $27,237.76 | 3,869 | BJQ0608 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,161.75 | 2,975 | BFYQFJ2 |
| 0.04% | ANNX | ANNEXON INC | -- | $26,263.59 | 5,349 | BMVV9R5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,257.48 | 1,604 | BT9K6D8 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $26,213.52 | 3,656 | BMCR7V2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,865.70 | 763 | BL95N25 |
| 0.04% | ABSI | ABSCI CORP | -- | $25,747.43 | 5,561 | BN94K69 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $23,311.53 | 1,269 | BD9GVY0 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,830.20 | 5,410 | BMCWKZ2 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $22,804.60 | 6,265 | BYWVTY5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $22,764.02 | 2,911 | BJ0LT31 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,122.76 | 6,028 | B3MZ6K5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,081.45 | 2,105 | BMFK3H6 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $21,703.68 | 1,536 | BRJJYT3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $21,246.60 | 2,083 | BLFBZ32 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,120.00 | 1,100 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $20,735.62 | 2,707 | BP0TQC5 |
| 0.03% | ARVN | ARVINAS INC | -- | $20,203.65 | 2,363 | BDZ30Q0 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,842.55 | 4,459 | BYV2W40 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,017.60 | 672 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $18,911.97 | 693 | BPBPCG8 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,449.99 | 4,511 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,374.40 | 2,112 | BSMLR16 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $18,040.23 | 1,989 | B91XRN2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,017.10 | 6,673 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $17,510.40 | 2,880 | BQHN6C7 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $17,359.11 | 2,349 | BP81R42 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,043.18 | 1,023 | BS2CR64 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,218.40 | 2,134 | B2Q9833 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,035.91 | 1,997 | BRCFFK6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $15,843.43 | 1,885 | BKLXFX5 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,702.12 | 8,308 | BFZNYB7 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,412.71 | 2,397 | BDRJH21 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,348.48 | 571 | BS2F741 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,750.72 | 1,072 | B9L5200 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $14,582.28 | 548 | B292NQ7 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $14,562.24 | 2,464 | BJDX8Z9 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $14,349.10 | 3,053 | BDDVW37 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,342.24 | 1,124 | BPRBTY7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,366.62 | 4,014 | BMXNGZ6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,094.14 | 2,186 | B12W3P6 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $12,837.45 | 11,163 | B4N8MH9 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $12,795.99 | 1,879 | B7F2TY6 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $12,694.31 | 787 | BTNMG41 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,688.94 | 4,631 | BFY7DC4 |
| 0.02% | OABI | OMNIAB INC | -- | $12,613.14 | 5,322 | BN13S71 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,084.82 | 7,414 | BFMLGR4 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,082.56 | 2,697 | BQ6C357 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,989.35 | 2,889 | BLN9Z50 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,717.96 | 4,013 | BDFKQ07 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $11,672.43 | 2,387 | BMVBZF5 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,631.39 | 3,557 | BK5MWR1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,563.02 | 2,646 | 2107437 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $11,223.99 | 3,609 | BKX9NQ0 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,148.75 | 1,125 | BM7V485 |
| 0.02% | IVVD | INVIVYD INC | -- | $10,653.76 | 10,244 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $10,601.18 | 1,873 | BZ0G875 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $10,493.22 | 3,721 | BZC0D70 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,313.92 | 6,176 | BN4JN37 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,016.72 | 1,736 | BL5B6Z1 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,147.42 | 3,426 | BYTYP72 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,883.06 | 3,611 | BZ8FPH3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,356.00 | 2,089 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,218.86 | 3,341 | B5LL2C2 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,177.00 | 5,525 | BRK0149 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,000.40 | 1,416 | BP81RK8 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $7,794.00 | 2,165 | BMF7DT9 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,700.70 | 1,158 | BQV0J03 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,582.92 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,501.38 | 1,147 | BP2NYN2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,442.85 | 1,711 | BKDQKM6 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,369.32 | 1,981 | BP7L561 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,037.88 | 1,052 | BKC9SX3 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,973.68 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,804.38 | 3,454 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,315.00 | 2,105 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,309.45 | 8,012 | BNNXX52 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,225.03 | 7,230 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,075.06 | 1,387 | 2517058 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,979.74 | 2,743 | BPTK6Z2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,889.34 | 7,136 | BMYTJP4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,398.73 | 2,303 | BLBR8D5 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $3,513.48 | 804 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,506.58 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,190.92 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,703.30 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 29.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,156,998 | -- | 3,524 | -- |
| 28.67% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,299,010 | -- | 3,374 | -- |
| 26.66% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 17,943,389 | -- | 3,137 | -- |
| 22.43% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,094,869 | -- | 2,639 | -- |
| 21.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,374,159 | -- | 2,513 | -- |
| 5.38% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,620,709 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $17,968,371.84 | 17,968,372 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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