BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,519,002
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/09/2026- NAV
- NAV Change
- Market Price $84.36
- Market Price Change $+0.70
- Trading Volume (M) 4,696
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,519,002
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/09/2026- NAV
- NAV Change
- Market Price $84.36
- Market Price Change $+0.70
- Trading Volume (M) 4,696
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/09/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.21% | GILD | GILEAD SCIENCES INC | -- | $4,261,705.37 | 29,993 | 2369174 |
| 5.00% | AMGN | AMGEN INC | -- | $4,092,956.00 | 11,510 | 2023607 |
| 4.91% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,016,998.98 | 8,991 | 2931034 |
| 4.23% | REGN | REGENERON PHARMACEUTICALS | -- | $3,462,235.65 | 4,509 | 2730190 |
| 2.26% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,849,287.68 | 5,756 | B00FWN1 |
| 1.83% | INSM | INSMED INC | -- | $1,493,443.22 | 9,358 | 2614487 |
| 1.38% | BIIB | BIOGEN INC | -- | $1,128,190.70 | 6,370 | 2455965 |
| 1.34% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,093,212.54 | 1,902 | 2430412 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $985,415.50 | 1,231 | BDVLM39 |
| 1.10% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $898,331.70 | 18,599 | BMVP7Y0 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $884,959.04 | 31,073 | BMW4NZ9 |
| 1.07% | MRNA | MODERNA INC | -- | $879,195.60 | 17,145 | BGSXTS3 |
| 1.02% | INCY | INCYTE CORP | -- | $837,734.40 | 8,640 | 2471950 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $827,780.66 | 8,603 | BL71K91 |
| 1.00% | ILMN | ILLUMINA INC | -- | $821,045.13 | 6,639 | 2613990 |
| 0.83% | VTRS | VIATRIS INC | -- | $680,323.07 | 49,987 | BMWS3X9 |
| 0.79% | SMMT | SUMMIT THERAPEUTICS INC | -- | $650,013.22 | 33,662 | BMTVQS7 |
| 0.79% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $645,849.12 | 2,672 | BV9G6B8 |
| 0.78% | BBIO | BRIDGEBIO PHARMA INC | -- | $635,651.84 | 8,417 | BK1KWG8 |
| 0.75% | MEDP | MEDPACE HOLDINGS INC | -- | $617,346.50 | 1,231 | BDCBC61 |
| 0.70% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $573,687.12 | 4,358 | 2623911 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $548,155.96 | 7,172 | BDJ0LS6 |
| 0.65% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $529,430.08 | 2,672 | B4Q5ZN4 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $522,727.10 | 997 | BD59BS7 |
| 0.63% | EXEL | EXELIXIS INC | -- | $511,997.75 | 11,275 | 2576941 |
| 0.61% | SNY | SANOFI-ADR | -- | $500,225.00 | 10,625 | 2964557 |
| 0.61% | GH | GUARDANT HEALTH INC | -- | $496,258.81 | 5,693 | BFXC911 |
| 0.57% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $470,105.00 | 8,350 | 2437071 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $454,933.08 | 4,946 | BK6H543 |
| 0.53% | ONC | BEONE MEDICINES LTD-ADR | -- | $435,026.96 | 1,388 | BYYWPW6 |
| 0.49% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $402,744.63 | 6,081 | BYQBFJ8 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $397,336.90 | 2,221 | BYZR4X4 |
| 0.47% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $387,170.16 | 1,209 | BQ721R4 |
| 0.47% | PCVX | VAXCYTE INC | -- | $385,439.12 | 6,248 | BKPVGH6 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $345,362.73 | 5,347 | BBBSBJ5 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $343,717.92 | 5,124 | 2975098 |
| 0.41% | ABVX | ABIVAX SA-ADR | -- | $335,089.54 | 2,666 | BLC89B2 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $333,869.80 | 44,635 | BNSP0B8 |
| 0.41% | TEM | TEMPUS AI INC-CL A | -- | $333,010.56 | 7,541 | BSLSJJ0 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $332,387.02 | 3,178 | BMVBZD3 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $328,337.43 | 1,271 | BD6JX35 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $309,481.05 | 3,543 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $288,419.54 | 2,771 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $263,205.45 | 7,047 | BLR6XK8 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $259,150.05 | 2,619 | BJDX8Y8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $255,375.45 | 2,965 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $254,564.05 | 3,593 | B17VCN9 |
| 0.31% | ALKS | ALKERMES PLC | -- | $252,646.20 | 7,235 | B3P6D26 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $251,340.96 | 3,666 | BRBCSP4 |
| 0.30% | TERN | TERNS PHARMACEUTICALS INC | -- | $242,669.52 | 4,617 | BMDJ0C9 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $235,200.00 | 12,250 | BT18HP9 |
| 0.29% | ERAS | ERASCA INC | -- | $233,353.12 | 13,442 | BNLYBF3 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $226,694.70 | 8,838 | BJRFSB7 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $225,607.50 | 5,550 | BYTQ6X1 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $217,911.70 | 4,430 | BFZQ0L8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $215,517.24 | 4,167 | BDHF4K6 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $211,627.08 | 3,612 | BRJ3GY4 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $206,473.68 | 5,193 | BLB0YQ9 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $205,917.60 | 2,380 | BM9HHL5 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $186,538.62 | 3,383 | BQS9486 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $180,157.98 | 4,546 | BDD19F8 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $177,878.60 | 865 | 2501578 |
| 0.22% | SYRE | SPYRE THERAPEUTICS INC | -- | $176,483.93 | 3,409 | BQBBDY8 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $175,378.68 | 5,428 | BTZRLN8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $174,999.30 | 4,990 | BP8JSP4 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $174,848.00 | 13,660 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $167,018.00 | 7,400 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $156,069.12 | 4,656 | BKY5JZ8 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $138,365.92 | 7,147 | BN15WD1 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $133,768.98 | 1,847 | BMH5RL1 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $133,623.60 | 2,101 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $132,811.65 | 6,885 | BD2B4V0 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $132,186.60 | 5,380 | BKX9VD3 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $130,012.08 | 2,662 | BGKG6G7 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $128,183.50 | 2,489 | B72ZBG4 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $126,801.14 | 3,098 | BL55460 |
| 0.15% | ALMS | ALUMIS INC | -- | $125,917.66 | 5,489 | BPLQG36 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $125,917.20 | 4,005 | BLFGJD5 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $121,032.90 | 5,847 | BP2P6L0 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $118,203.00 | 3,813 | BK0VHF6 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $117,531.02 | 2,578 | BMFD115 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $117,484.00 | 5,108 | BKS3RS7 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $116,457.59 | 4,423 | BK6L288 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $116,385.00 | 7,759 | BN2R582 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $112,254.00 | 2,650 | BFXC933 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $111,516.10 | 1,657 | BMGJZJ8 |
| 0.13% | VCYT | VERACYTE INC | -- | $108,188.85 | 3,451 | BFTWZY0 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $107,702.10 | 10,890 | 2100362 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $102,779.60 | 10,340 | B9NSBM2 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $101,146.50 | 4,550 | B8DPDT7 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $100,302.45 | 4,195 | BJ62Z18 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $96,337.80 | 4,485 | BLB0YH0 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $94,806.04 | 3,829 | BN7Q7R7 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,328.69 | 1,993 | BRXB0C0 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $93,356.12 | 3,436 | BP9N0G0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $92,705.76 | 4,328 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $92,121.12 | 5,772 | BFWLC09 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $89,565.60 | 6,684 | BJ5FZ74 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $88,887.50 | 3,250 | BPCQZY9 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $87,894.30 | 9,451 | BNZB1X8 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $87,136.85 | 2,479 | BJQ05Z6 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $85,010.73 | 2,317 | BMVNDH9 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $83,715.56 | 2,543 | BCBVTX1 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $82,599.08 | 4,769 | BPCK358 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $82,522.16 | 1,204 | BDRW1L7 |
| 0.10% | GRAL | GRAIL INC | -- | $80,423.96 | 1,691 | BSLSSX7 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $79,042.60 | 2,795 | BBC9WC7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $77,976.22 | 973 | BCDWBX6 |
| 0.10% | INVA | INNOVIVA INC | -- | $77,803.00 | 3,215 | BDDXF67 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $75,407.71 | 1,939 | BQKXDX4 |
| 0.09% | PHVS | PHARVARIS NV | -- | $75,308.74 | 2,782 | BMZ2X38 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $75,007.91 | 22,661 | BM9FJ13 |
| 0.09% | VCEL | VERICEL CORP | -- | $74,065.95 | 2,205 | BSBMN89 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $74,027.80 | 5,566 | BJH9ZN0 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,249.92 | 2,512 | BKSGZN7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $72,495.36 | 4,464 | BMVLGP2 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $71,714.84 | 17,884 | BF0DMK7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $70,920.24 | 5,128 | BYZM6C2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $70,835.40 | 2,070 | BR3T9B6 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $67,070.09 | 6,823 | BK4PZ38 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $66,684.80 | 3,664 | BMX9K07 |
| 0.08% | PGEN | PRECIGEN INC | -- | $65,595.74 | 15,362 | BKM5C84 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,259.98 | 10,646 | BN89V40 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $64,044.14 | 1,949 | BQXJKH2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $60,534.43 | 1,903 | BLCD809 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $60,445.00 | 2,750 | BQB42F1 |
| 0.07% | NVAX | NOVAVAX INC | -- | $60,394.88 | 7,072 | BJDQXG4 |
| 0.07% | HROW | HARROW INC | -- | $60,036.90 | 1,610 | BHNDW86 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,763.55 | 3,311 | BP7KZP7 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $58,518.68 | 8,173 | BYZG9R0 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $58,341.60 | 15,768 | BWJDYK1 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $58,241.32 | 2,089 | BSRK699 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $57,890.56 | 3,479 | BMZ4LN0 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $56,192.62 | 3,586 | BYP80F1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,055.33 | 11,891 | BNC1BX1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $54,340.00 | 4,940 | BYSS4X4 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $52,885.55 | 895 | BL95N25 |
| 0.06% | SVRA | SAVARA INC | -- | $51,861.45 | 8,835 | BYXGN81 |
| 0.06% | ALVO | ALVOTECH SA | -- | $51,624.00 | 14,340 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $51,142.62 | 3,594 | BMGS7L1 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $50,327.20 | 2,365 | BQB42H3 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $48,859.25 | 1,793 | BMGTLY5 |
| 0.06% | GERN | GERON CORP | -- | $48,776.64 | 27,714 | 2370381 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,609.75 | 1,379 | BX7RSN3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $48,244.69 | 1,943 | BQNKXX2 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $47,798.25 | 631 | BNSP8K3 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $45,277.28 | 13,162 | BL53SR3 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $45,236.04 | 4,358 | BKVDFF7 |
| 0.05% | QURE | UNIQURE NV | -- | $44,091.50 | 2,705 | BJFSR88 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $43,790.25 | 2,195 | BD06CS0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,296.04 | 7,204 | BLR7H87 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $43,228.80 | 3,420 | BJLKVS6 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $42,624.75 | 5,295 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,827.92 | 1,756 | B3X26D8 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $41,696.43 | 2,031 | BZ7PJQ1 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $41,122.11 | 2,693 | BP6C0S2 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,093.03 | 1,969 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $39,908.05 | 3,185 | BGCYWN8 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $39,013.65 | 2,565 | BM90J52 |
| 0.05% | ANNX | ANNEXON INC | -- | $38,577.62 | 6,283 | BMVV9R5 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $38,388.26 | 2,642 | BMFX8Y7 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $38,073.42 | 4,059 | BRXYZ57 |
| 0.04% | OMER | OMEROS CORP | -- | $36,647.07 | 3,077 | B4NB858 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $36,426.55 | 2,201 | BMNDK09 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,079.68 | 11,564 | BMFJJ97 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $35,905.00 | 8,350 | BZ0QMB7 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,503.11 | 4,293 | BMCR7V2 |
| 0.04% | MNKD | MANNKIND CORP | -- | $34,245.12 | 13,377 | BF081J4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,551.94 | 1,886 | BT9K6D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,435.30 | 3,778 | BYZD465 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,057.60 | 2,272 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $32,633.96 | 3,494 | BFYQFJ2 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,517.30 | 1,163 | BGL0JK3 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $31,185.20 | 7,355 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $31,030.26 | 2,778 | BDZ30Q0 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,875.28 | 2,472 | BMFK3H6 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $30,840.38 | 1,487 | BD9GVY0 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,224.70 | 1,290 | BKLCWZ3 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $28,392.87 | 9,757 | BFZNYB7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $28,142.40 | 1,804 | BRJJYT3 |
| 0.03% | PSNL | PERSONALIS INC | -- | $27,666.87 | 4,543 | BJQ0608 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $27,507.87 | 7,837 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,410.40 | 3,384 | BQHN6C7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,437.60 | 7,066 | B3MZ6K5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,369.44 | 816 | BPBPCG8 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,171.20 | 3,420 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,714.88 | 2,336 | B91XRN2 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $24,445.32 | 2,346 | BRCFFK6 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,072.39 | 789 | BQD3J33 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $23,989.17 | 4,713 | BMXNGZ6 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,758.40 | 2,480 | BSMLR16 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,721.53 | 2,443 | BLFBZ32 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $23,365.15 | 1,663 | BP81RK8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,867.81 | 2,891 | BJDX8Z9 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $22,855.68 | 4,096 | BMC3HS7 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $22,624.04 | 10,378 | BBNBTD2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,084.32 | 5,296 | BYVQJ96 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $22,013.55 | 923 | BTNMG41 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,785.76 | 2,214 | BKLXFX5 |
| 0.03% | IVVD | INVIVYD INC | -- | $21,413.40 | 12,030 | BM8NHS1 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,358.80 | 5,235 | BYV2W40 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,317.55 | 2,505 | B2Q9833 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $21,193.26 | 3,586 | BDDVW37 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $20,376.67 | 3,169 | BQ6C357 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,803.44 | 3,391 | BLN9Z50 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $19,764.05 | 6,355 | BMCWKZ2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,694.08 | 2,198 | BZ0G875 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,257.60 | 6,528 | BN94K69 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,882.08 | 2,576 | B12W3P6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,692.46 | 2,757 | BP81R42 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,392.64 | 644 | B292NQ7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,373.68 | 5,436 | BFY7DC4 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,699.85 | 13,111 | B4N8MH9 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,590.95 | 1,261 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,222.40 | 2,208 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,970.40 | 4,714 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,961.26 | 1,322 | BPRBTY7 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $16,524.27 | 1,323 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,757.44 | 2,784 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,235.20 | 3,174 | BP0TQC5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,090.40 | 7,255 | BN4JN37 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,854.60 | 4,369 | BZC0D70 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,360.64 | 672 | BS2F741 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,684.00 | 3,110 | 2107437 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,244.26 | 4,178 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,802.23 | 8,709 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,606.53 | 1,357 | BQV0J03 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,273.20 | 4,024 | BYTYP72 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $12,247.82 | 4,238 | BZ8FPH3 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,176.18 | 2,542 | BMF7DT9 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,987.88 | 4,236 | BKX9NQ0 |
| 0.01% | EOLS | EVOLUS INC | -- | $11,927.12 | 2,813 | BDRJH21 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,841.39 | 4,873 | BKRRKY7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,820.40 | 2,038 | BL5B6Z1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,706.85 | 6,489 | BRK0149 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,367.73 | 2,451 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,135.26 | 1,233 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,133.64 | 2,559 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,994.67 | 2,011 | BKDQKM6 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,410.40 | 3,921 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $9,373.50 | 6,249 | BN13S71 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,634.96 | 3,222 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,951.72 | 4,057 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,670.00 | 1,625 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,591.44 | 1,346 | BP2NYN2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,963.40 | 9,410 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,483.96 | 2,324 | BP7L561 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,380.34 | 2,473 | BKTV702 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,336.70 | 8,484 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,086.05 | 8,379 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,807.46 | 2,986 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,353.44 | 2,704 | BLBR8D5 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,733.84 | 10,048 | BJ0CK86 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,685.50 | 945 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,303.30 | 4,235 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $26.76 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 37.88% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,995,977 | -- | 5,213 | -- |
| 30.02% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,568,459 | -- | 4,132 | -- |
| 26.90% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,011,722 | -- | 3,702 | -- |
| 19.18% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,691,230 | -- | 2,639 | -- |
| 14.46% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,832,341 | -- | 1,990 | -- |
| 4.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,763,755 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $27,146,300.48 | 27,146,300 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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