BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 7/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 10.19% | 6.76% | -8.68% | 0.27% | -23.18% | -0.36% | -5.86% | -6.05% | 13.44% | 04/07/2010 |
| BIB NAV | 10.39% | 6.81% | -8.47% | 0.46% | -23.08% | -0.27% | -5.82% | -6.03% | 13.44% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/14/2025- NAV $54.76
- NAV Change $+0.17
- Market Price $54.80
- Market Price Change $+0.21
- Trading Volume (M) 9,099
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/14/2025- NAV $54.76
- NAV Change $+0.17
- Market Price $54.80
- Market Price Change $+0.21
- Trading Volume (M) 9,099
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 8/14/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.06% | GILD | GILEAD SCIENCES INC | -- | $2,798,755.30 | 23,515 | 2369174 |
| 4.71% | AMGN | AMGEN INC | -- | $2,607,384.78 | 8,982 | 2023607 |
| 4.13% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,285,596.80 | 5,856 | 2931034 |
| 4.03% | REGN | REGENERON PHARMACEUTICALS | -- | $2,227,657.92 | 3,936 | 2730190 |
| 3.40% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,881,602.50 | 4,250 | B00FWN1 |
| 3.14% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,734,030.06 | 22,098 | 2989044 |
| 1.57% | INSM | INSMED INC | -- | $870,616.25 | 6,815 | 2614487 |
| 1.39% | ARGX | ARGENX SE - ADR | -- | $769,867.40 | 1,180 | BDVLM39 |
| 1.34% | BIIB | BIOGEN INC | -- | $739,741.08 | 5,482 | 2455965 |
| 1.33% | SMMT | SUMMIT THERAPEUTICS INC | -- | $734,939.70 | 27,786 | BMTVQS7 |
| 1.13% | INCY | INCYTE CORP | -- | $623,970.72 | 7,242 | 2471950 |
| 1.07% | ILMN | ILLUMINA INC | -- | $592,833.07 | 5,923 | 2613990 |
| 1.03% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $571,954.20 | 15,765 | BMVP7Y0 |
| 0.95% | UTHR | UNITED THERAPEUTICS CORP | -- | $526,757.28 | 1,688 | 2430412 |
| 0.93% | SNY | SANOFI-ADR | -- | $516,244.08 | 10,527 | 2964557 |
| 0.89% | MEDP | MEDPACE HOLDINGS INC | -- | $493,059.50 | 1,075 | BDCBC61 |
| 0.88% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $486,240.93 | 3,703 | 2623911 |
| 0.87% | ONC | BEONE MEDICINES LTD-ADR | -- | $478,471.05 | 1,545 | BYYWPW6 |
| 0.85% | VTRS | VIATRIS INC | -- | $469,419.28 | 43,912 | BMWS3X9 |
| 0.81% | TEM | TEMPUS AI INC | -- | $450,157.92 | 6,288 | BSLSJJ0 |
| 0.79% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $435,930.80 | 2,270 | BV9G6B8 |
| 0.76% | BNTX | BIONTECH SE-ADR | -- | $421,272.60 | 3,738 | BK6H543 |
| 0.75% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $416,150.00 | 7,175 | 2437071 |
| 0.71% | EXEL | EXELIXIS INC | -- | $392,394.00 | 10,200 | 2576941 |
| 0.70% | MRNA | MODERNA INC | -- | $386,177.61 | 14,469 | BGSXTS3 |
| 0.66% | BBIO | BRIDGEBIO PHARMA INC | -- | $363,582.72 | 7,104 | BK1KWG8 |
| 0.56% | VRNA | VERONA PHARMA PLC - ADR | -- | $309,809.61 | 2,943 | BYWPZK5 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $308,608.47 | 831 | BD59BS7 |
| 0.55% | HALO | HALOZYME THERAPEUTICS INC | -- | $302,139.40 | 4,610 | 2975098 |
| 0.54% | ROIV | ROIVANT SCIENCES LTD | -- | $298,849.50 | 25,434 | BMW4NZ9 |
| 0.51% | GH | GUARDANT HEALTH INC | -- | $279,768.60 | 4,635 | BFXC911 |
| 0.49% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $269,157.69 | 2,307 | B4Q5ZN4 |
| 0.46% | IONS | IONIS PHARMACEUTICALS INC | -- | $255,171.75 | 5,955 | BDJ0LS6 |
| 0.45% | RVMD | REVOLUTION MEDICINES INC | -- | $251,023.38 | 6,969 | BL71K91 |
| 0.42% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $229,622.40 | 2,380 | BF2YWG4 |
| 0.38% | RNA | AVIDITY BIOSCIENCES INC | -- | $207,775.70 | 4,510 | BMWHPY1 |
| 0.36% | AXSM | AXSOME THERAPEUTICS INC | -- | $200,317.50 | 1,842 | BYZR4X4 |
| 0.34% | NUVL | NUVALENT INC-A | -- | $190,694.40 | 2,483 | BMVBZD3 |
| 0.34% | CRSP | CRISPR THERAPEUTICS AG | -- | $190,047.42 | 3,231 | BDHF4K6 |
| 0.32% | ALKS | ALKERMES PLC | -- | $174,477.24 | 6,174 | B3P6D26 |
| 0.31% | MRUS | MERUS NV | -- | $173,374.60 | 2,590 | BZBY005 |
| 0.31% | CYTK | CYTOKINETICS INC | -- | $173,000.96 | 4,468 | BBBSBJ5 |
| 0.29% | KRYS | KRYSTAL BIOTECH INC | -- | $162,506.73 | 1,081 | BD6JX35 |
| 0.28% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $153,606.86 | 6,262 | 2713317 |
| 0.27% | PCVX | VAXCYTE INC | -- | $151,712.61 | 4,827 | BKPVGH6 |
| 0.27% | ADMA | ADMA BIOLOGICS INC | -- | $151,576.04 | 8,932 | B9NSBM2 |
| 0.27% | AKRO | AKERO THERAPEUTICS INC | -- | $149,418.47 | 2,983 | BK7Y2V9 |
| 0.27% | ACLX | ARCELLX INC | -- | $148,175.32 | 2,062 | BPCJ1Q2 |
| 0.26% | PTCT | PTC THERAPEUTICS INC | -- | $144,395.50 | 2,965 | B17VCN9 |
| 0.23% | APLS | APELLIS PHARMACEUTICALS INC | -- | $129,869.24 | 4,702 | BYTQ6X1 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $127,521.81 | 2,319 | BDCBCD8 |
| 0.22% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $120,129.99 | 1,853 | BJDX8Y8 |
| 0.21% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $115,241.76 | 3,056 | BMX9K07 |
| 0.21% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $114,694.08 | 3,552 | BFZQ0L8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $111,036.38 | 722 | 2501578 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $110,107.14 | 11,726 | BFNF1D6 |
| 0.20% | XENE | XENON PHARMACEUTICALS INC | -- | $108,983.16 | 2,871 | BRJ3GY4 |
| 0.20% | INDV | INDIVIOR PLC | -- | $108,157.56 | 4,668 | BP0BQQ5 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $105,714.00 | 4,200 | BP8JSP4 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $104,063.45 | 3,505 | BDD19F8 |
| 0.19% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,608.37 | 3,537 | BJ62Z18 |
| 0.18% | KYMR | KYMERA THERAPEUTICS INC | -- | $101,215.80 | 2,436 | BMPRZV5 |
| 0.18% | IMVT | IMMUNOVANT INC | -- | $97,204.00 | 6,395 | BJRFSB7 |
| 0.18% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $97,036.26 | 5,167 | BYQBFJ8 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $89,489.62 | 33,022 | BNSP0B8 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $88,346.15 | 2,095 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $88,017.20 | 2,930 | BFTWZY0 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $85,108.08 | 1,572 | BMH5RL1 |
| 0.15% | ALVO | ALVOTECH SA | -- | $84,605.93 | 9,983 | BPNTJ34 |
| 0.15% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $84,334.92 | 14,953 | BM9FJ13 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $82,029.52 | 11,521 | B19FQ48 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $79,860.49 | 3,277 | BK0VHF6 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $79,485.56 | 2,167 | BCBVTX1 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $78,693.12 | 1,296 | BMGJZJ8 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $78,647.94 | 5,439 | BD2B4V0 |
| 0.14% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $78,423.48 | 2,148 | BKSGZN7 |
| 0.14% | ZLAB | ZAI LAB LTD-ADR | -- | $75,658.38 | 2,166 | BD9GVY0 |
| 0.14% | OCUL | OCULAR THERAPEUTIX INC | -- | $75,394.00 | 5,960 | BNZB1X8 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $74,643.10 | 3,677 | B8DPDT7 |
| 0.13% | CGON | CG ONCOLOGY INC | -- | $74,037.92 | 2,852 | BRBCSP4 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $73,437.28 | 5,684 | BJ5FZ74 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,900.00 | 810 | BCDWBX6 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $71,270.80 | 4,460 | BKX9VD3 |
| 0.12% | VCEL | VERICEL CORP | -- | $67,390.68 | 1,884 | BSBMN89 |
| 0.12% | BEAM | BEAM THERAPEUTICS INC | -- | $66,359.32 | 3,764 | BK6L288 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $66,155.05 | 7,829 | 2100362 |
| 0.12% | APGE | APOGEE THERAPEUTICS INC | -- | $65,566.40 | 1,720 | BM9HHL5 |
| 0.12% | TWST | TWIST BIOSCIENCE CORP | -- | $64,659.28 | 2,242 | BGKG6G7 |
| 0.11% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $63,027.72 | 3,573 | BLB0YQ9 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $61,114.95 | 5,055 | BFWLC09 |
| 0.11% | TVTX | TRAVERE THERAPEUTICS INC | -- | $60,578.29 | 3,323 | BLFGJD5 |
| 0.10% | NVAX | NOVAVAX INC | -- | $57,145.80 | 6,060 | BJDQXG4 |
| 0.10% | JANX | JANUX THERAPEUTICS INC | -- | $55,283.58 | 2,214 | BMFX8Y7 |
| 0.10% | TXG | 10X GENOMICS INC-CLASS A | -- | $55,025.44 | 4,156 | BKS3RS7 |
| 0.10% | HROW | HARROW INC | -- | $54,933.73 | 1,373 | BHNDW86 |
| 0.10% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $54,800.62 | 3,934 | BKY5JZ8 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $53,290.44 | 1,764 | BNFWZS4 |
| 0.10% | SPRY | ARS PHARMACEUTICALS INC | -- | $53,177.25 | 3,675 | BMCR7V2 |
| 0.10% | DYN | DYNE THERAPEUTICS INC | -- | $53,162.50 | 4,253 | BN15WD1 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $52,715.52 | 1,584 | BRXB0C0 |
| 0.09% | ARDX | ARDELYX INC | -- | $52,273.84 | 8,951 | BN89V40 |
| 0.09% | WVE | WAVE LIFE SCIENCES LTD | -- | $51,383.97 | 5,767 | BYZG9R0 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $50,750.22 | 2,386 | BL55460 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,251.50 | 11,167 | BL53SR3 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $49,884.60 | 4,260 | BLR6XK8 |
| 0.09% | ETNB | 89BIO INC | -- | $49,704.20 | 5,462 | BK1K484 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,160.22 | 1,487 | BLCD809 |
| 0.09% | INVA | INNOVIVA INC | -- | $49,047.12 | 2,349 | BDDXF67 |
| 0.09% | GRFS | GRIFOLS SA-ADR | -- | $49,017.36 | 4,564 | B8K7T65 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $48,856.50 | 3,619 | BDGMC59 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $48,341.89 | 4,171 | BYSS4X4 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $47,715.66 | 4,493 | BRJZSK0 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $47,415.87 | 3,219 | BN7Q7R7 |
| 0.08% | CVAC | CUREVAC NV | -- | $46,416.24 | 8,424 | BN4RD42 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,703.48 | 1,203 | BX7RSN3 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,741.60 | 5,992 | BLR7H87 |
| 0.08% | GRAL | GRAIL INC | -- | $43,314.28 | 1,346 | BSLSSX7 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,282.68 | 1,732 | B3X26D8 |
| 0.08% | LENZ | LENZ THERAPEUTICS INC | -- | $43,078.23 | 1,053 | BQV0J03 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $42,226.60 | 3,874 | BYZM6C2 |
| 0.08% | MNKD | MANNKIND CORP | -- | $42,072.70 | 11,371 | BF081J4 |
| 0.07% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $41,303.37 | 2,229 | BQS9486 |
| 0.07% | SYRE | SPYRE THERAPEUTICS INC | -- | $38,069.88 | 2,258 | BQBBDY8 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $37,280.10 | 2,607 | BPCQZY9 |
| 0.07% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $36,347.40 | 762 | BQ721R4 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $36,297.72 | 1,836 | BMFD115 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $36,055.62 | 1,569 | BBC9WC7 |
| 0.06% | STOK | STOKE THERAPEUTICS INC | -- | $35,078.31 | 2,043 | BJQ05Z6 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $34,638.00 | 1,725 | BZ7PJQ1 |
| 0.06% | GERN | GERON CORP | -- | $34,553.50 | 23,830 | 2370381 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $34,448.94 | 2,438 | BP9N0G0 |
| 0.06% | QURE | UNIQURE NV | -- | $32,317.44 | 2,048 | BJFSR88 |
| 0.06% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $32,291.34 | 3,194 | BYTYP72 |
| 0.06% | CRMD | CORMEDIX INC | -- | $32,004.18 | 2,538 | BJ0LT31 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $30,610.30 | 12,494 | BF0DMK7 |
| 0.05% | NRIX | NURIX THERAPEUTICS INC | -- | $30,117.12 | 2,852 | BMVLGP2 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $28,945.77 | 8,439 | BMFJJ97 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $28,714.98 | 9,767 | BNC1BX1 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $28,514.43 | 3,807 | BJH9ZN0 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $28,060.60 | 4,055 | BP2P6L0 |
| 0.05% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $28,047.35 | 3,335 | BPCK358 |
| 0.05% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $27,938.75 | 2,575 | BMGS7L1 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $27,478.44 | 2,827 | BPQYY97 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $27,347.64 | 2,612 | BJLKVS6 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,962.00 | 1,700 | BQS7491 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $26,749.40 | 3,386 | BRXYZ57 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,413.80 | 2,660 | BKVDFF7 |
| 0.05% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $25,348.41 | 669 | BQD3J33 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $25,048.31 | 3,007 | BFYQFJ2 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,210.74 | 1,871 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $24,149.42 | 7,166 | BZ0QMB7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $24,087.00 | 1,860 | BD06CS0 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $23,833.60 | 1,280 | BMGTLY5 |
| 0.04% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $23,700.00 | 3,792 | BLB0YH0 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,294.34 | 762 | BL95N25 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $22,963.68 | 5,172 | BK4PZ38 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,934.34 | 2,673 | 2107437 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,124.36 | 3,268 | BMDJ0C9 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $21,947.03 | 1,099 | BDRW1L7 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $21,918.40 | 1,520 | BM7V485 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $21,743.46 | 6,414 | BN2R582 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $21,516.79 | 961 | BQ80NC6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,405.60 | 1,080 | BKLCWZ3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $21,377.40 | 3,239 | BYZD465 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $21,293.00 | 1,990 | BMVNDH9 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $21,015.00 | 1,401 | BKVF0J2 |
| 0.04% | PGEN | PRECIGEN INC | -- | $20,431.40 | 11,044 | BKM5C84 |
| 0.04% | RAPP | RAPPORT THERAPEUTICS INC | -- | $20,408.04 | 1,366 | BR3T9B6 |
| 0.04% | XNCR | XENCOR INC | -- | $20,371.95 | 2,663 | BGCYWN8 |
| 0.04% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $19,518.45 | 1,015 | BKC9SX3 |
| 0.04% | SVRA | SAVARA INC | -- | $19,462.66 | 6,466 | BYXGN81 |
| 0.03% | ARVN | ARVINAS INC | -- | $19,335.48 | 2,731 | BDZ30Q0 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $18,409.20 | 1,160 | BYXV9H7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $18,209.40 | 2,046 | BLFBZ32 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $17,893.00 | 2,900 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $17,879.68 | 4,912 | BPBJFM7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,611.66 | 554 | B292NQ7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $17,104.53 | 699 | BPBPCG8 |
| 0.03% | RGNX | REGENXBIO INC | -- | $17,005.62 | 1,877 | BZ0G875 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $16,759.38 | 2,211 | BM90J52 |
| 0.03% | ERAS | ERASCA INC | -- | $16,640.43 | 10,599 | BNLYBF3 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $16,240.00 | 2,320 | BP81R42 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $16,232.84 | 2,014 | B91XRN2 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $16,033.84 | 13,588 | BWFZX59 |
| 0.03% | ALMS | ALUMIS INC | -- | $15,698.64 | 3,576 | BPLQG36 |
| 0.03% | EOLS | EVOLUS INC | -- | $15,436.80 | 2,412 | BDRJH21 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,429.40 | 2,884 | BDDVW37 |
| 0.03% | PSNL | PERSONALIS INC | -- | $15,401.30 | 3,305 | BJQ0608 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $15,349.05 | 7,415 | BBNBTD2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $15,272.76 | 3,716 | BYVQJ96 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $14,477.52 | 1,432 | BMWXFT4 |
| 0.03% | YMAB | Y-MABS THERAPEUTICS INC | -- | $14,424.45 | 1,695 | BG31GH0 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $14,416.00 | 3,400 | BMC3HS7 |
| 0.03% | ABSI | ABSCI CORP | -- | $14,316.00 | 4,772 | BN94K69 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,270.36 | 2,111 | BMYRFN8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $14,006.20 | 5,387 | BMCWKZ2 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $13,992.25 | 2,885 | BYP80F1 |
| 0.03% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,878.70 | 7,502 | BFMLGR4 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,809.21 | 11,227 | B4N8MH9 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $13,465.60 | 2,560 | BMZ4LN0 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $12,975.48 | 542 | BNSP8K3 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $12,304.30 | 1,733 | BKLXFX5 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,213.93 | 4,031 | BDFKQ07 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $12,184.38 | 1,651 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $11,264.96 | 749 | BN72KB0 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,174.98 | 3,202 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $11,168.80 | 3,035 | BFY7DC4 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $11,098.53 | 971 | BQB9HM8 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $10,959.84 | 2,124 | BMFK3H6 |
| 0.02% | HUMA | HUMACYTE INC | -- | $10,911.52 | 5,804 | BMYTJP4 |
| 0.02% | NGNE | NEUROGENE INC | -- | $10,786.80 | 534 | BS2F741 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,727.33 | 2,085 | BMF7DT9 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $10,206.96 | 2,396 | BMXNGZ6 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,009.35 | 2,301 | BP7KZP7 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,908.80 | 1,760 | BL5B6Z1 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $9,776.25 | 1,975 | BYX2Z16 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,769.90 | 4,105 | BMVV9R5 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,768.15 | 2,205 | B12W3P6 |
| 0.02% | CDXS | CODEXIS INC | -- | $9,610.00 | 3,100 | B5LL2C2 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $9,595.20 | 1,999 | BP7L561 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,562.16 | 6,052 | BN4JN37 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $9,270.72 | 3,132 | BZ8FPH3 |
| 0.02% | ALEC | ALECTOR INC | -- | $9,202.86 | 3,741 | BJ4LDC4 |
| 0.02% | OABI | OMNIAB INC | -- | $9,154.00 | 4,577 | BN13S71 |
| 0.02% | OMER | OMEROS CORP | -- | $9,031.04 | 2,192 | B4NB858 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,756.88 | 8,184 | BFZNYB7 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,002.41 | 3,757 | BZC0D70 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,700.40 | 2,070 | BY7RB53 |
| 0.01% | CRGX | CARGO THERAPEUTICS INC | -- | $7,693.50 | 1,725 | BQHN2F2 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,444.50 | 1,418 | BP81RK8 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $6,742.40 | 6,880 | BPG5P75 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $6,477.78 | 6,054 | B3MZ6K5 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,243.95 | 2,657 | BKX9NQ0 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,192.00 | 800 | B9L5200 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $5,949.18 | 1,242 | BQ6C357 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $5,939.52 | 552 | BTNMG41 |
| 0.01% | NKTX | NKARTA INC | -- | $5,841.00 | 2,655 | BK80YJ8 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,724.18 | 1,617 | BSMLR16 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,608.98 | 3,978 | BKMQF66 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $4,589.23 | 4,289 | BCZS820 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,348.16 | 2,528 | BMW5LX6 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,823.20 | 2,360 | BFDV8K0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,617.78 | 2,297 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,542.17 | 1,957 | BNLYBJ7 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $2,619.34 | 2,318 | BLBR8D5 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,500.18 | 5,297 | BJL38Z1 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,465.12 | 3,160 | BF12XC2 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,462.40 | 912 | BMF1LJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,376.14 | 1,406 | BNKF6N0 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,630.47 | 1,173 | BP2TPK4 |
| -- | PEPG | PEPGEN INC | -- | $1,578.96 | 1,224 | BMTX3D7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,387.54 | 187 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,281.60 | 480 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $857.28 | 456 | BS2FKQ4 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 30.91% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,097,092 | -- | 3,675 | -- |
| 27.40% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 15,152,443 | -- | 3,257 | -- |
| 26.30% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 14,547,648 | -- | 3,127 | -- |
| 16.81% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 9,299,888 | -- | 1,999 | -- |
| 16.18% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 8,950,967 | -- | 1,924 | -- |
| 16.14% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 8,927,706 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,968,155.40 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $13,809,007.54 | 13,809,008 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Earnings Ratio--
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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