BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 5/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 3.79% | -3.99% | 1.49% | 6.15% | 98.53% | 18.55% | 0.58% | -- | 16.40% | 04/07/2010 |
| BIB Market Price | 3.64% | -4.03% | 1.26% | 6.04% | 98.32% | 18.49% | 0.55% | -- | 16.40% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,617,903
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/29/2026- NAV
- NAV Change
- Market Price $100.48
- Market Price Change $+2.20
- Trading Volume (M) 10,937
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,617,903
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/29/2026- NAV
- NAV Change
- Market Price $100.48
- Market Price Change $+2.20
- Trading Volume (M) 10,937
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/29/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.59% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,838,810.95 | 7,683 | 2931034 |
| 4.40% | AMGN | AMGEN INC | -- | $3,680,133.85 | 10,207 | 2023607 |
| 3.86% | GILD | GILEAD SCIENCES INC | -- | $3,230,763.42 | 25,574 | 2369174 |
| 2.55% | REGN | REGENERON PHARMACEUTICALS | -- | $2,133,622.37 | 3,377 | 2730190 |
| 1.61% | RVMD | REVOLUTION MEDICINES INC | -- | $1,342,561.40 | 6,970 | BL71K91 |
| 1.54% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,284,737.04 | 4,377 | B00FWN1 |
| 1.25% | BIIB | BIOGEN INC | -- | $1,048,705.83 | 4,841 | 2455965 |
| 1.08% | MRNA | MODERNA INC | -- | $907,215.20 | 13,016 | BGSXTS3 |
| 1.07% | ILMN | ILLUMINA INC | -- | $898,799.30 | 4,963 | 2613990 |
| 0.99% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $830,202.78 | 14,542 | BMVP7Y0 |
| 0.99% | ARGX | ARGENX SE - ADR | -- | $826,688.76 | 906 | BDVLM39 |
| 0.98% | ROIV | ROIVANT SCIENCES LTD | -- | $819,072.32 | 23,584 | BMW4NZ9 |
| 0.91% | UTHR | UNITED THERAPEUTICS CORP | -- | $758,528.64 | 1,392 | 2430412 |
| 0.90% | INCY | INCYTE CORP | -- | $751,252.32 | 6,552 | 2471950 |
| 0.89% | INSM | INSMED INC | -- | $744,596.66 | 7,109 | 2614487 |
| 0.80% | GH | GUARDANT HEALTH INC | -- | $668,615.26 | 4,349 | BFXC911 |
| 0.74% | VTRS | VIATRIS INC | -- | $619,775.01 | 38,187 | BMWS3X9 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $560,660.00 | 3,298 | 2623911 |
| 0.64% | ASND | ASCENDIS PHARMA A/S | -- | $532,937.70 | 2,021 | BWXJHM8 |
| 0.60% | MEDP | MEDPACE HOLDINGS INC | -- | $499,963.20 | 935 | BDCBC61 |
| 0.59% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $489,227.76 | 2,058 | B4Q5ZN4 |
| 0.55% | BBIO | BRIDGEBIO PHARMA INC | -- | $462,376.21 | 6,421 | BK1KWG8 |
| 0.54% | EXEL | EXELIXIS INC | -- | $447,430.04 | 8,243 | 2576941 |
| 0.52% | IONS | IONIS PHARMACEUTICALS INC | -- | $437,097.73 | 5,417 | BDJ0LS6 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $406,287.20 | 1,685 | BYZR4X4 |
| 0.48% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $399,150.96 | 757 | BD59BS7 |
| 0.46% | CYTK | CYTOKINETICS INC | -- | $387,957.96 | 4,446 | BBBSBJ5 |
| 0.44% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $371,588.00 | 4,616 | BYQBFJ8 |
| 0.44% | KRYS | KRYSTAL BIOTECH INC | -- | $366,427.35 | 969 | BD6JX35 |
| 0.44% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $365,397.12 | 6,336 | 2437071 |
| 0.44% | SMMT | SUMMIT THERAPEUTICS INC | -- | $364,458.32 | 25,451 | BMTVQS7 |
| 0.43% | BNTX | BIONTECH SE-ADR | -- | $359,319.12 | 3,812 | BK6H543 |
| 0.40% | TEM | TEMPUS AI INC-CL A | -- | $333,591.51 | 5,721 | BSLSJJ0 |
| 0.40% | SNY | SANOFI-ADR | -- | $331,327.47 | 7,629 | 2964557 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $321,112.96 | 916 | BQ721R4 |
| 0.37% | ONC | BEONE MEDICINES LTD-ADR | -- | $313,479.19 | 1,081 | BYYWPW6 |
| 0.36% | IBRX | IMMUNITYBIO INC | -- | $301,196.88 | 34,344 | BNSP0B8 |
| 0.36% | HALO | HALOZYME THERAPEUTICS INC | -- | $300,153.02 | 3,889 | 2975098 |
| 0.36% | NUVL | NUVALENT INC-A | -- | $298,153.14 | 2,414 | BMVBZD3 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $294,945.36 | 2,698 | BMPRZV5 |
| 0.34% | ALKS | ALKERMES PLC | -- | $286,971.39 | 5,463 | B3P6D26 |
| 0.33% | PCVX | VAXCYTE INC | -- | $273,246.48 | 4,734 | BKPVGH6 |
| 0.32% | APGE | APOGEE THERAPEUTICS INC | -- | $268,933.08 | 2,028 | BM9HHL5 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $259,249.32 | 6,732 | BJRFSB7 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $256,956.00 | 2,850 | BQBBDY8 |
| 0.31% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $256,639.30 | 2,110 | BDCBCD8 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $247,479.96 | 2,249 | BF2YWG4 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $246,000.00 | 2,000 | BJDX8Y8 |
| 0.27% | PTCT | PTC THERAPEUTICS INC | -- | $221,625.69 | 2,717 | B17VCN9 |
| 0.26% | COGT | COGENT BIOSCIENCES INC | -- | $217,098.96 | 5,604 | BLR6XK8 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $215,882.88 | 3,928 | BFZQ0L8 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $213,227.16 | 2,892 | BRBCSP4 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $206,638.32 | 658 | 2501578 |
| 0.24% | TWST | TWIST BIOSCIENCE CORP | -- | $200,752.76 | 2,041 | BGKG6G7 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $190,431.71 | 3,167 | BRJ3GY4 |
| 0.22% | ERAS | ERASCA INC | -- | $186,539.71 | 10,199 | BNLYBF3 |
| 0.22% | ABVX | ABIVAX SA-ADR | -- | $182,781.15 | 1,901 | BLC89B2 |
| 0.22% | ORKA | ORUKA THERAPEUTICS INC | -- | $182,760.24 | 1,976 | BKVF0J2 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $180,836.11 | 10,459 | BFNF1D6 |
| 0.21% | CRSP | CRISPR THERAPEUTICS AG | -- | $178,291.40 | 3,164 | BDHF4K6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $177,815.00 | 3,050 | BLFGJD5 |
| 0.20% | CAI | CARIS LIFE SCIENCES INC | -- | $169,789.76 | 9,268 | BT18HP9 |
| 0.20% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $166,323.15 | 3,573 | BV2DHY6 |
| 0.20% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $164,957.48 | 3,998 | BTZRLN8 |
| 0.19% | VCYT | VERACYTE INC | -- | $157,637.61 | 2,619 | BFTWZY0 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $154,464.64 | 4,744 | BP2P6L0 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $144,324.84 | 3,527 | BKY5JZ8 |
| 0.17% | TXG | 10X GENOMICS INC-CLASS A | -- | $142,730.30 | 3,842 | BKS3RS7 |
| 0.17% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $141,447.60 | 5,613 | 2713317 |
| 0.17% | RLAY | RELAY THERAPEUTICS INC | -- | $138,851.16 | 7,034 | BN2R582 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $134,757.45 | 5,205 | BD2B4V0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $132,223.02 | 2,558 | BQS9486 |
| 0.16% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $129,789.84 | 3,832 | BP8JSP4 |
| 0.15% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $127,775.46 | 3,459 | BDD19F8 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $117,676.65 | 3,367 | BK6L288 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $115,207.94 | 5,419 | BN15WD1 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $112,328.60 | 5,249 | BJ5FZ74 |
| 0.13% | ALMS | ALUMIS INC | -- | $109,889.86 | 4,049 | BPLQG36 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $109,769.52 | 4,102 | BKX9VD3 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $105,227.45 | 2,879 | BK0VHF6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $101,575.10 | 2,354 | BL55460 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $101,547.45 | 1,997 | BMFD115 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $99,035.04 | 3,228 | BJ62Z18 |
| 0.12% | QURE | UNIQURE NV | -- | $98,239.47 | 2,073 | BJFSR88 |
| 0.12% | GRAL | GRAIL INC | -- | $96,293.12 | 1,408 | BSLSSX7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,863.20 | 1,520 | BRXB0C0 |
| 0.11% | IRON | DISC MEDICINE INC | -- | $93,348.50 | 1,253 | BMGJZJ8 |
| 0.11% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $89,107.20 | 1,904 | B72ZBG4 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $86,759.91 | 4,657 | BJH9ZN0 |
| 0.10% | TARS | TARSUS PHARMACEUTICALS INC | -- | $86,499.12 | 1,412 | BMH5RL1 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $83,898.30 | 1,558 | BQXJKH2 |
| 0.10% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $81,322.13 | 2,767 | BMX9K07 |
| 0.10% | ABCL | ABCELLERA BIOLOGICS INC | -- | $81,289.32 | 10,011 | BL53SR3 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $80,803.80 | 3,388 | BMVLGP2 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $79,589.70 | 8,334 | 2100362 |
| 0.10% | PHVS | PHARVARIS NV | -- | $79,485.90 | 2,290 | BMZ2X38 |
| 0.09% | KOD | KODIAK SCIENCES INC | -- | $77,442.48 | 2,052 | BFXC933 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $76,023.97 | 4,577 | BYZM6C2 |
| 0.09% | VCEL | VERICEL CORP | -- | $75,357.04 | 1,672 | BSBMN89 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,178.00 | 1,950 | BCBVTX1 |
| 0.09% | MLYS | MINERALYS THERAPEUTICS INC | -- | $72,737.28 | 2,706 | BP9N0G0 |
| 0.08% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,072.10 | 7,179 | BNZB1X8 |
| 0.08% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $70,669.11 | 4,209 | BFWLC09 |
| 0.08% | PGEN | PRECIGEN INC | -- | $69,216.64 | 11,692 | BKM5C84 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $68,180.20 | 3,646 | BPCK358 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $67,075.32 | 1,898 | BKSGZN7 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $66,155.20 | 2,768 | BP7KZP7 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $66,140.38 | 2,042 | BJQ05Z6 |
| 0.08% | CMPS | COMPASS PATHWAYS PLC | -- | $65,810.69 | 4,367 | BMC3HS7 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $64,711.74 | 2,487 | BBC9WC7 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $64,705.92 | 12,072 | BWJDYK1 |
| 0.08% | GHRS | GH RESEARCH PLC | -- | $63,903.07 | 2,243 | BP6C0S2 |
| 0.08% | ADMA | ADMA BIOLOGICS INC | -- | $63,620.37 | 7,601 | B9NSBM2 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $63,509.66 | 1,478 | BQKXDX4 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $63,479.07 | 17,203 | BM9FJ13 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $63,412.30 | 1,570 | BR3T9B6 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $63,410.06 | 9,422 | BNC1BX1 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $63,314.46 | 2,907 | BN7Q7R7 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $63,227.70 | 2,155 | BQB42F1 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $63,067.32 | 956 | BDRW1L7 |
| 0.07% | ANIP | ANI PHARMACEUTICALS INC | -- | $62,665.68 | 745 | BCDWBX6 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $62,614.50 | 1,950 | BMVNDH9 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $61,642.82 | 14,642 | BF0DMK7 |
| 0.07% | SRPT | SAREPTA THERAPEUTICS INC | -- | $58,906.22 | 3,461 | B8DPDT7 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $58,793.04 | 3,798 | BYSS4X4 |
| 0.07% | ABSI | ABSCI CORP | -- | $58,089.30 | 5,118 | BN94K69 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $57,671.30 | 2,393 | BPCQZY9 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $57,639.86 | 1,598 | BZ7PJQ1 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $57,391.02 | 5,529 | BK4PZ38 |
| 0.07% | INVA | INNOVIVA INC | -- | $55,952.52 | 2,418 | BDDXF67 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $54,347.04 | 3,102 | BRXYZ57 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $52,965.15 | 2,073 | BQB42H3 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $52,664.00 | 1,816 | BSRK699 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,414.25 | 1,525 | BMGTLY5 |
| 0.06% | SEPN | SEPTERNA INC | -- | $51,291.00 | 1,476 | BQNKXX2 |
| 0.06% | NVAX | NOVAVAX INC | -- | $50,469.12 | 5,392 | BJDQXG4 |
| 0.06% | HROW | HARROW INC | -- | $50,203.00 | 1,220 | BHNDW86 |
| 0.06% | PSNL | PERSONALIS INC | -- | $47,203.75 | 3,433 | BJQ0608 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $45,744.50 | 479 | BNSP8K3 |
| 0.05% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $44,382.78 | 1,459 | BLCD809 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,839.36 | 5,664 | BLR7H87 |
| 0.05% | MNKD | MANNKIND CORP | -- | $42,955.44 | 10,131 | BF081J4 |
| 0.05% | ARDX | ARDELYX INC | -- | $42,373.46 | 8,102 | BN89V40 |
| 0.05% | SVRA | SAVARA INC | -- | $40,509.54 | 6,718 | BYXGN81 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $39,950.32 | 2,759 | BYP80F1 |
| 0.05% | EYPT | EYEPOINT INC | -- | $38,802.50 | 2,750 | BMGS7L1 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $38,318.70 | 1,065 | BX7RSN3 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $38,071.44 | 3,036 | BFYQFJ2 |
| 0.05% | ALVO | ALVOTECH SA | -- | $38,066.76 | 10,233 | BPNTJ34 |
| 0.05% | XNCR | XENCOR INC | -- | $37,908.00 | 2,430 | BGCYWN8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,153.14 | 2,017 | BM90J52 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $36,402.05 | 1,459 | BT9K6D8 |
| 0.04% | WVE | WAVE LIFE SCIENCES LTD | -- | $35,846.48 | 6,311 | BYZG9R0 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $35,050.60 | 2,873 | BMZ4LN0 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $34,476.23 | 3,395 | BKVDFF7 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $33,052.20 | 1,777 | BRJJYT3 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,983.54 | 898 | BGL0JK3 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $32,366.10 | 1,290 | B3X26D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,955.61 | 2,913 | BYZD465 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,481.25 | 9,125 | BMFJJ97 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $30,908.43 | 4,837 | BMCWKZ2 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,650.00 | 2,000 | BMFX8Y7 |
| 0.04% | SLDB | SOLID BIOSCIENCES INC | -- | $30,550.22 | 3,226 | BQHN6C7 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $30,340.80 | 2,709 | BDDVW37 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,307.68 | 6,476 | BZ0QMB7 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $29,946.66 | 1,446 | BNFWZS4 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,916.47 | 5,371 | BMVV9R5 |
| 0.04% | GRFS | GRIFOLS SA-ADR | -- | $29,327.33 | 4,001 | B8K7T65 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $29,163.52 | 2,048 | BMFK3H6 |
| 0.03% | TBPH | THERAVANCE BIOPHARMA INC | -- | $28,831.40 | 1,690 | BMNDK09 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,446.79 | 2,617 | BJLKVS6 |
| 0.03% | SPRY | ARS PHARMACEUTICALS INC | -- | $27,879.92 | 3,257 | BMCR7V2 |
| 0.03% | GERN | GERON CORP | -- | $27,342.90 | 21,033 | 2370381 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $27,151.38 | 1,938 | BLFBZ32 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $26,699.86 | 7,139 | BYWVTY5 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $26,592.30 | 8,442 | BBNBTD2 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $25,123.74 | 11,317 | BFZNYB7 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $24,895.08 | 2,403 | BP0TQC5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $24,271.36 | 998 | BKLCWZ3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,697.28 | 607 | BQD3J33 |
| 0.03% | OMER | OMEROS CORP | -- | $23,496.61 | 2,371 | B4NB858 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $23,354.76 | 1,716 | BQS7491 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $23,323.20 | 3,390 | BP81R42 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,211.40 | 5,398 | B3MZ6K5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,981.56 | 4,578 | BYV2W40 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,102.08 | 1,716 | BKLXFX5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $22,026.12 | 5,921 | BPBJFM7 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $21,948.90 | 690 | BL95N25 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,548.89 | 621 | BPBPCG8 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,051.85 | 1,695 | BZ0G875 |
| 0.02% | ZLAB | ZAI LAB LTD-ADR | -- | $19,845.98 | 1,078 | BD9GVY0 |
| 0.02% | CRMD | CORMEDIX INC | -- | $19,634.80 | 2,570 | BJ0LT31 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $19,459.44 | 1,144 | BS2CR64 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,818.94 | 6,401 | BFY7DC4 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,687.52 | 10,224 | B4N8MH9 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,558.22 | 2,118 | BDZ30Q0 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,498.54 | 1,993 | BSMLR16 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $17,128.46 | 1,718 | B91XRN2 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,122.56 | 4,116 | BYVQJ96 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,785.60 | 520 | BS2F741 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $16,629.17 | 5,347 | BK5MWR1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $16,616.60 | 1,540 | BL5B6Z1 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,102.40 | 5,032 | BZ8FPH3 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,050.00 | 1,070 | BPRBTY7 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,764.40 | 3,624 | BKX9NQ0 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $15,634.53 | 2,007 | BP2NYN2 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,400.80 | 2,160 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $14,597.64 | 492 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $13,917.76 | 1,891 | B2Q9833 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,842.54 | 954 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,685.49 | 1,671 | B7F2TY6 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,376.13 | 2,573 | BQ6C357 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $12,356.19 | 1,783 | BRCFFK6 |
| 0.01% | OABI | OMNIAB INC | -- | $12,220.35 | 4,755 | BN13S71 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,095.80 | 1,970 | B12W3P6 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,087.42 | 2,622 | BLN9Z50 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,064.60 | 3,580 | BDFKQ07 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $10,905.60 | 3,408 | BMXNGZ6 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,850.40 | 6,576 | BFMLGR4 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,700.95 | 2,119 | BMVBZF5 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,447.28 | 6,074 | BN4JN37 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,973.53 | 1,759 | BP7L561 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,791.70 | 1,270 | BP81RK8 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,779.25 | 767 | BTNMG41 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,350.64 | 1,924 | BMF7DT9 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,333.75 | 1,965 | BPRB2N7 |
| 0.01% | IVVD | INVIVYD INC | -- | $9,114.25 | 9,658 | BM8NHS1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,876.42 | 3,337 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $8,490.72 | 2,352 | 2107437 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,146.32 | 2,184 | BJDX8Z9 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $7,901.40 | 3,039 | BYTYP72 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,337.00 | 5,060 | BRK0149 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,286.40 | 3,680 | BKRRKY7 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,093.57 | 649 | BM7V485 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,088.40 | 1,980 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,955.05 | 2,985 | B5LL2C2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $6,342.60 | 930 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,337.05 | 1,527 | BKDQKM6 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,090.88 | 1,228 | 2517058 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,937.36 | 2,076 | BLBR8D5 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $5,909.76 | 1,026 | BQV0J03 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,815.99 | 7,280 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $5,766.29 | 6,487 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,757.81 | 3,253 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,482.40 | 2,492 | BPTK6Z2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,227.34 | 7,113 | BNNXX52 |
| -- | PEPG | PEPGEN INC | -- | $4,042.38 | 2,271 | BMTX3D7 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,714.06 | 717 | BTXQTX3 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,286.50 | 1,878 | BKTV702 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,817.92 | 3,685 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,262.14 | 7,696 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 39.10% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 32,697,314 | -- | 4,982 | -- |
| 31.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 26,442,690 | -- | 4,029 | -- |
| 27.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 23,128,329 | -- | 3,524 | -- |
| 20.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 17,319,995 | -- | 2,639 | -- |
| 19.72% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 16,493,045 | -- | 2,513 | -- |
| 4.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,154,436 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $31,723,354.79 | 31,723,355 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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