BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $81,001,330
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/02/2026- NAV
- NAV Change
- Market Price $81.77
- Market Price Change $-0.80
- Trading Volume (M) 3,167
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $81,001,330
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/02/2026- NAV
- NAV Change
- Market Price $81.77
- Market Price Change $-0.80
- Trading Volume (M) 3,167
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/01/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.31% | GILD | GILEAD SCIENCES INC | -- | $4,335,971.50 | 30,905 | 2369174 |
| 5.13% | AMGN | AMGEN INC | -- | $4,189,900.80 | 11,860 | 2023607 |
| 5.07% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,143,863.90 | 9,265 | 2931034 |
| 4.42% | REGN | REGENERON PHARMACEUTICALS | -- | $3,611,880.75 | 4,647 | 2730190 |
| 2.39% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,950,026.36 | 5,932 | B00FWN1 |
| 1.95% | INSM | INSMED INC | -- | $1,589,580.12 | 9,642 | 2614487 |
| 1.48% | BIIB | BIOGEN INC | -- | $1,206,331.92 | 6,564 | 2455965 |
| 1.37% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,117,729.20 | 1,960 | 2430412 |
| 1.15% | ARGX | ARGENX SE - ADR | -- | $943,019.28 | 1,269 | BDVLM39 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $929,310.85 | 19,165 | BMVP7Y0 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $891,353.28 | 32,017 | BMW4NZ9 |
| 1.08% | MRNA | MODERNA INC | -- | $883,880.01 | 17,667 | BGSXTS3 |
| 1.07% | RVMD | REVOLUTION MEDICINES INC | -- | $874,443.60 | 8,865 | BL71K91 |
| 1.06% | ILMN | ILLUMINA INC | -- | $866,275.83 | 6,841 | 2613990 |
| 1.03% | INCY | INCYTE CORP | -- | $839,458.60 | 8,902 | 2471950 |
| 0.86% | VTRS | VIATRIS INC | -- | $702,040.41 | 51,507 | BMWS3X9 |
| 0.80% | SMMT | SUMMIT THERAPEUTICS INC | -- | $656,259.12 | 34,686 | BMTVQS7 |
| 0.79% | BBIO | BRIDGEBIO PHARMA INC | -- | $645,704.85 | 8,673 | BK1KWG8 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $628,572.96 | 2,754 | BV9G6B8 |
| 0.76% | MEDP | MEDPACE HOLDINGS INC | -- | $621,150.12 | 1,269 | BDCBC61 |
| 0.73% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $595,194.40 | 4,490 | 2623911 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $555,210.70 | 7,390 | BDJ0LS6 |
| 0.67% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $544,145.68 | 1,027 | BD59BS7 |
| 0.65% | GH | GUARDANT HEALTH INC | -- | $534,777.05 | 5,867 | BFXC911 |
| 0.64% | SNY | SANOFI-ADR | -- | $522,595.77 | 10,949 | 2964557 |
| 0.63% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $518,495.58 | 2,754 | B4Q5ZN4 |
| 0.63% | EXEL | EXELIXIS INC | -- | $511,612.68 | 11,617 | 2576941 |
| 0.60% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $492,492.96 | 8,604 | 2437071 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $455,684.32 | 5,096 | BK6H543 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $441,069.20 | 1,430 | BYYWPW6 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $397,503.60 | 1,245 | BQ721R4 |
| 0.48% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $394,193.80 | 6,265 | BYQBFJ8 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $393,204.42 | 2,289 | BYZR4X4 |
| 0.46% | PCVX | VAXCYTE INC | -- | $376,623.00 | 6,438 | BKPVGH6 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $366,954.49 | 5,509 | BBBSBJ5 |
| 0.45% | TEM | TEMPUS AI INC-CL A | -- | $365,470.13 | 7,771 | BSLSJJ0 |
| 0.42% | NUVL | NUVALENT INC-A | -- | $345,865.36 | 3,274 | BMVBZD3 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $345,312.00 | 5,280 | 2975098 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $338,913.19 | 1,309 | BD6JX35 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $328,375.74 | 45,991 | BNSP0B8 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $315,937.56 | 2,748 | BLC89B2 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $310,079.43 | 3,651 | BMPRZV5 |
| 0.37% | ACLX | ARCELLX INC | -- | $300,186.00 | 2,616 | BPCJ1Q2 |
| 0.36% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $295,977.85 | 2,855 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $269,206.60 | 3,055 | BF2YWG4 |
| 0.32% | ALKS | ALKERMES PLC | -- | $261,297.75 | 7,455 | B3P6D26 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $255,877.64 | 7,261 | BLR6XK8 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $255,379.38 | 2,699 | BJDX8Y8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $254,581.25 | 3,703 | B17VCN9 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $252,332.62 | 3,778 | BRBCSP4 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $251,122.03 | 4,757 | BMDJ0C9 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $241,458.86 | 12,622 | BT18HP9 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $230,950.02 | 5,718 | BYTQ6X1 |
| 0.28% | ERAS | ERASCA INC | -- | $229,910.00 | 13,850 | BNLYBF3 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $228,560.60 | 9,106 | BJRFSB7 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $225,233.40 | 4,564 | BFZQ0L8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $213,290.86 | 5,351 | BLB0YQ9 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $211,000.18 | 3,722 | BRJ3GY4 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $209,541.33 | 4,293 | BDHF4K6 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $206,556.48 | 2,452 | BM9HHL5 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $178,905.96 | 14,076 | BFNF1D6 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $177,861.42 | 891 | 2501578 |
| 0.21% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $174,842.45 | 3,485 | BQS9486 |
| 0.21% | SYRE | SPYRE THERAPEUTICS INC | -- | $171,785.70 | 3,513 | BQBBDY8 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,456.10 | 5,594 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $171,293.88 | 4,684 | BDD19F8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $170,212.32 | 7,626 | 2713317 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $168,709.02 | 5,142 | BP8JSP4 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $159,005.72 | 4,798 | BKY5JZ8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $139,629.60 | 7,095 | BD2B4V0 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $135,838.68 | 2,742 | BGKG6G7 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $133,628.66 | 1,903 | BMH5RL1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $133,610.40 | 5,544 | BKX9VD3 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $133,306.50 | 7,365 | BN15WD1 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $131,943.60 | 2,565 | B72ZBG4 |
| 0.16% | TVTX | TRAVERE THERAPEUTICS INC | -- | $129,670.34 | 4,127 | BLFGJD5 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $129,276.00 | 3,192 | BL55460 |
| 0.16% | ALMS | ALUMIS INC | -- | $128,538.15 | 5,655 | BPLQG36 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $127,850.50 | 6,025 | BP2P6L0 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $127,613.92 | 3,929 | BK0VHF6 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $116,871.30 | 2,730 | BFXC933 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $116,071.20 | 5,264 | BKS3RS7 |
| 0.14% | VCYT | VERACYTE INC | -- | $115,182.00 | 3,555 | BFTWZY0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $110,579.46 | 1,707 | BMGJZJ8 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $110,370.54 | 4,557 | BK6L288 |
| 0.13% | ORKA | ORUKA THERAPEUTICS INC | -- | $109,180.95 | 2,165 | BKVF0J2 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $105,243.60 | 11,220 | 2100362 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $103,745.44 | 4,688 | B8DPDT7 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $100,370.24 | 2,656 | BMFD115 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $99,393.84 | 6,888 | BJ5FZ74 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $98,981.82 | 4,621 | BLB0YH0 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $98,810.89 | 2,053 | BRXB0C0 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $97,057.94 | 10,654 | B9NSBM2 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $94,206.60 | 3,945 | BN7Q7R7 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $93,491.40 | 3,540 | BP9N0G0 |
| 0.11% | GRAL | GRAIL INC | -- | $93,424.80 | 1,743 | BSLSSX7 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $92,598.66 | 4,323 | BJ62Z18 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $92,015.56 | 5,948 | BFWLC09 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $91,876.00 | 4,460 | BV2DHY6 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $91,374.36 | 2,387 | BMVNDH9 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $89,611.99 | 2,621 | BCBVTX1 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $86,847.12 | 3,348 | BPCQZY9 |
| 0.11% | RLAY | RELAY THERAPEUTICS INC | -- | $86,106.15 | 7,995 | BN2R582 |
| 0.10% | PHVS | PHARVARIS NV | -- | $84,403.70 | 2,866 | BMZ2X38 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $82,476.10 | 1,997 | BQKXDX4 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $81,734.45 | 2,555 | BJQ05Z6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,125.87 | 9,739 | BNZB1X8 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $78,366.38 | 2,879 | BBC9WC7 |
| 0.09% | INVA | INNOVIVA INC | -- | $77,557.33 | 3,313 | BDDXF67 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,187.88 | 1,003 | BCDWBX6 |
| 0.09% | VCEL | VERICEL CORP | -- | $73,943.76 | 2,271 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,360.48 | 2,588 | BKSGZN7 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $71,932.80 | 3,776 | BMX9K07 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $71,447.94 | 23,349 | BM9FJ13 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,208.00 | 4,600 | BMVLGP2 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $70,501.55 | 4,913 | BPCK358 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $70,345.20 | 1,240 | BDRW1L7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $70,118.68 | 5,284 | BYZM6C2 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $67,520.44 | 2,132 | BR3T9B6 |
| 0.08% | ARDX | ARDELYX INC | -- | $67,026.70 | 10,970 | BN89V40 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $66,422.88 | 5,736 | BJH9ZN0 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $64,870.61 | 2,009 | BQXJKH2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $63,576.60 | 18,428 | BF0DMK7 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $63,419.62 | 7,031 | BK4PZ38 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $62,544.65 | 2,153 | BSRK699 |
| 0.08% | PGEN | PRECIGEN INC | -- | $62,204.04 | 15,828 | BKM5C84 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $60,117.60 | 16,248 | BWJDYK1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,437.91 | 1,961 | BLCD809 |
| 0.07% | HROW | HARROW INC | -- | $58,742.94 | 1,658 | BHNDW86 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,566.87 | 3,411 | BP7KZP7 |
| 0.07% | NVAX | NOVAVAX INC | -- | $58,449.76 | 7,288 | BJDQXG4 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $58,097.00 | 2,834 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $57,515.43 | 8,421 | BYZG9R0 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $55,175.60 | 5,090 | BYSS4X4 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $54,205.20 | 3,585 | BMZ4LN0 |
| 0.07% | ALVO | ALVOTECH SA | -- | $53,489.12 | 14,776 | BPNTJ34 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,304.42 | 3,694 | BYP80F1 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $52,810.43 | 12,253 | BNC1BX1 |
| 0.06% | SVRA | SAVARA INC | -- | $50,794.74 | 9,103 | BYXGN81 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $50,543.48 | 923 | BL95N25 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $49,576.60 | 2,435 | BQB42H3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $48,813.11 | 2,003 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $48,226.08 | 3,704 | BMGS7L1 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,602.62 | 13,562 | BL53SR3 |
| 0.06% | GERN | GERON CORP | -- | $47,402.96 | 28,556 | 2370381 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,248.25 | 1,421 | BX7RSN3 |
| 0.06% | QURE | UNIQURE NV | -- | $47,072.43 | 2,787 | BJFSR88 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $45,020.25 | 5,457 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $44,828.88 | 7,422 | BLR7H87 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,734.34 | 1,847 | BMGTLY5 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $44,699.97 | 2,261 | BD06CS0 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $43,649.55 | 651 | BNSP8K3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,249.90 | 1,810 | B3X26D8 |
| 0.05% | XNCR | XENCOR INC | -- | $41,110.93 | 3,281 | BGCYWN8 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,066.96 | 2,029 | BNFWZS4 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $40,848.00 | 2,775 | BP6C0S2 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,780.33 | 4,183 | BRXYZ57 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $39,641.42 | 2,093 | BZ7PJQ1 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,496.22 | 2,722 | BMFX8Y7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,257.36 | 3,524 | BJLKVS6 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,890.08 | 8,604 | BZ0QMB7 |
| 0.05% | OMER | OMEROS CORP | -- | $38,305.68 | 3,171 | B4NB858 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $37,003.60 | 2,342 | BQS7491 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,843.42 | 2,643 | BM90J52 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,343.80 | 11,916 | BMFJJ97 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,909.28 | 2,267 | BMNDK09 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,870.53 | 4,423 | BMCR7V2 |
| 0.04% | MNKD | MANNKIND CORP | -- | $35,008.82 | 13,783 | BF081J4 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,706.00 | 6,475 | BMVV9R5 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $34,560.24 | 7,579 | BYWVTY5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $34,467.12 | 1,944 | BT9K6D8 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $33,562.75 | 4,490 | BKVDFF7 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,316.50 | 1,330 | BKLCWZ3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $32,724.00 | 3,600 | BFYQFJ2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,459.28 | 3,892 | BYZD465 |
| 0.04% | ARVN | ARVINAS INC | -- | $32,426.46 | 2,862 | BDZ30Q0 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $32,310.62 | 1,858 | BRJJYT3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,181.22 | 1,533 | BD9GVY0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $30,707.36 | 4,681 | BJQ0608 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,406.64 | 1,199 | BGL0JK3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $28,399.80 | 7,282 | B3MZ6K5 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $28,111.34 | 3,694 | BDDVW37 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $28,053.48 | 2,548 | BMFK3H6 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,911.34 | 10,694 | BBNBTD2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $27,374.25 | 8,075 | BPBJFM7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,855.20 | 840 | BPBPCG8 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $25,735.68 | 10,053 | BFZNYB7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,726.68 | 3,486 | BQHN6C7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,738.48 | 3,524 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,152.24 | 2,408 | B91XRN2 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $23,716.40 | 4,220 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,684.97 | 2,517 | BLFBZ32 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $23,091.24 | 1,713 | BP81RK8 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,730.76 | 4,857 | BMXNGZ6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,541.54 | 5,458 | BYVQJ96 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,523.34 | 2,282 | BKLXFX5 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $22,511.58 | 2,418 | BRCFFK6 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,416.12 | 2,556 | BSMLR16 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,357.50 | 813 | BQD3J33 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,335.30 | 5,395 | BYV2W40 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,282.92 | 2,979 | BJDX8Z9 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,861.07 | 2,581 | B2Q9833 |
| 0.03% | ABSI | ABSCI CORP | -- | $21,186.90 | 6,726 | BN94K69 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,790.31 | 951 | BTNMG41 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,760.64 | 664 | B292NQ7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,746.75 | 3,495 | BLN9Z50 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,538.32 | 2,264 | BZ0G875 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,034.70 | 2,841 | BP81R42 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $18,795.63 | 6,549 | BMCWKZ2 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,763.78 | 2,654 | B12W3P6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,512.55 | 3,265 | BQ6C357 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,318.90 | 1,362 | BPRBTY7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,237.15 | 13,509 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,585.96 | 4,858 | BDFKQ07 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,478.24 | 5,602 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,848.03 | 1,299 | B9L5200 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,564.68 | 3,204 | 2107437 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,486.68 | 12,396 | BM8NHS1 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,284.60 | 3,270 | BP0TQC5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,933.47 | 1,363 | BM7V485 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,622.75 | 7,475 | BN4JN37 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,385.76 | 2,276 | B7F2TY6 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,297.10 | 2,870 | BMVBZF5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,988.72 | 692 | BS2F741 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,080.65 | 1,399 | BQV0J03 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,852.60 | 4,146 | BYTYP72 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,838.00 | 2,620 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,557.79 | 4,501 | BZC0D70 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,494.69 | 2,899 | BDRJH21 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,382.74 | 8,973 | BFMLGR4 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,351.66 | 5,021 | BKRRKY7 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,782.80 | 4,364 | BKX9NQ0 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,635.38 | 6,687 | BRK0149 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $11,540.08 | 4,306 | BK5MWR1 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,487.00 | 2,100 | BL5B6Z1 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,395.26 | 4,366 | BZ8FPH3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,958.50 | 2,525 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,521.63 | 2,637 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,157.70 | 2,073 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $10,044.84 | 6,439 | BN13S71 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,977.35 | 1,271 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,320.19 | 4,181 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,569.60 | 3,320 | BPTK6Z2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,262.64 | 1,386 | BP2NYN2 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,031.34 | 4,041 | B5LL2C2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,014.42 | 2,394 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,602.98 | 9,696 | BNNXX52 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,535.52 | 8,742 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,432.00 | 1,675 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,939.17 | 2,549 | BKTV702 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,352.24 | 3,076 | BMTX3D7 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,109.87 | 8,633 | BMYTJP4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,095.42 | 2,786 | BLBR8D5 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,979.57 | 973 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,779.21 | 10,354 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,513.96 | 4,363 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $24.87 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 36.41% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 29,729,883 | -- | 5,061 | -- |
| 30.81% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,159,670 | -- | 4,283 | -- |
| 26.63% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,746,696 | -- | 3,702 | -- |
| 18.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,502,304 | -- | 2,639 | -- |
| 14.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,689,877 | -- | 1,990 | -- |
| 4.55% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,718,438 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,680,346.59 | 25,680,347 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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