BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,476,544
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/21/2026- NAV
- NAV Change
- Market Price $86.89
- Market Price Change $-1.62
- Trading Volume (M) 5,260
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,476,544
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/21/2026- NAV
- NAV Change
- Market Price $86.89
- Market Price Change $-1.62
- Trading Volume (M) 5,260
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/21/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.69% | GILD | GILEAD SCIENCES INC | -- | $3,873,940.56 | 29,064 | 2369174 |
| 4.66% | AMGN | AMGEN INC | -- | $3,846,223.58 | 11,153 | 2023607 |
| 4.60% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,803,572.08 | 8,712 | 2931034 |
| 3.95% | REGN | REGENERON PHARMACEUTICALS | -- | $3,265,215.84 | 4,369 | 2730190 |
| 2.08% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,720,114.11 | 5,577 | B00FWN1 |
| 1.55% | INSM | INSMED INC | -- | $1,278,406.64 | 9,068 | 2614487 |
| 1.50% | RVMD | REVOLUTION MEDICINES INC | -- | $1,241,230.40 | 8,336 | BL71K91 |
| 1.39% | BIIB | BIOGEN INC | -- | $1,147,683.40 | 6,172 | 2455965 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,056,886.78 | 1,843 | 2430412 |
| 1.16% | ARGX | ARGENX SE - ADR | -- | $960,818.34 | 1,193 | BDVLM39 |
| 1.09% | MRNA | MODERNA INC | -- | $900,922.99 | 16,613 | BGSXTS3 |
| 1.08% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $891,728.56 | 18,022 | BMVP7Y0 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $881,951.19 | 30,111 | BMW4NZ9 |
| 1.04% | SMMT | SUMMIT THERAPEUTICS INC | -- | $860,489.22 | 32,619 | BMTVQS7 |
| 1.03% | ILMN | ILLUMINA INC | -- | $849,027.34 | 6,433 | 2613990 |
| 0.98% | INCY | INCYTE CORP | -- | $805,650.06 | 8,373 | 2471950 |
| 0.86% | VTRS | VIATRIS INC | -- | $713,491.74 | 48,438 | BMWS3X9 |
| 0.75% | -- | ASCENDIS PHARMA A/S | -- | $622,110.81 | 2,589 | -- |
| 0.75% | BBIO | BRIDGEBIO PHARMA INC | -- | $621,324.08 | 8,156 | BK1KWG8 |
| 0.74% | MEDP | MEDPACE HOLDINGS INC | -- | $614,275.70 | 1,193 | BDCBC61 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $549,919.06 | 4,223 | 2623911 |
| 0.65% | BNTX | BIONTECH SE-ADR | -- | $534,898.80 | 4,793 | BK6H543 |
| 0.63% | IONS | IONIS PHARMACEUTICALS INC | -- | $519,721.00 | 6,950 | BDJ0LS6 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $515,288.67 | 2,589 | B4Q5ZN4 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $509,748.54 | 966 | BD59BS7 |
| 0.61% | EXEL | EXELIXIS INC | -- | $501,394.14 | 10,926 | 2576941 |
| 0.60% | GH | GUARDANT HEALTH INC | -- | $498,425.76 | 5,516 | BFXC911 |
| 0.59% | SNY | SANOFI-ADR | -- | $485,203.35 | 10,295 | 2964557 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $441,930.42 | 8,091 | 2437071 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $420,056.95 | 1,345 | BYYWPW6 |
| 0.51% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $418,697.65 | 5,893 | BYQBFJ8 |
| 0.49% | TEM | TEMPUS AI INC-CL A | -- | $402,981.05 | 7,307 | BSLSJJ0 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $399,464.48 | 1,172 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $393,751.44 | 2,152 | BYZR4X4 |
| 0.44% | PCVX | VAXCYTE INC | -- | $366,569.70 | 6,054 | BKPVGH6 |
| 0.42% | IBRX | IMMUNITYBIO INC | -- | $350,349.30 | 43,253 | BNSP0B8 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $340,975.60 | 5,182 | BBBSBJ5 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $339,655.65 | 4,965 | 2975098 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $335,917.12 | 1,232 | BD6JX35 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $329,960.40 | 3,080 | BMVBZD3 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $302,344.31 | 3,433 | BMPRZV5 |
| 0.35% | ERAS | ERASCA INC | -- | $291,912.66 | 13,026 | BNLYBF3 |
| 0.35% | ABVX | ABIVAX SA-ADR | -- | $287,823.69 | 2,583 | BLC89B2 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $284,314.65 | 2,685 | BDCBCD8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $255,175.68 | 3,552 | BRBCSP4 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $250,829.17 | 6,829 | BLR6XK8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $247,272.93 | 11,871 | BT18HP9 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $245,863.03 | 3,481 | B17VCN9 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $243,975.16 | 2,873 | BF2YWG4 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $242,218.20 | 8,565 | BJRFSB7 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $236,871.54 | 2,538 | BJDX8Y8 |
| 0.29% | TERN | TERNS PHARMACEUTICALS INC | -- | $236,495.64 | 4,474 | BMDJ0C9 |
| 0.28% | SYRE | SPYRE THERAPEUTICS INC | -- | $235,404.81 | 3,303 | BQBBDY8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $235,008.72 | 7,011 | B3P6D26 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $224,270.52 | 4,038 | BDHF4K6 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $220,175.32 | 5,378 | BYTQ6X1 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $209,523.16 | 2,306 | BM9HHL5 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $206,493.30 | 4,293 | BFZQ0L8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $198,713.68 | 5,032 | BLB0YQ9 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $197,400.00 | 3,500 | BRJ3GY4 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $189,949.46 | 838 | 2501578 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $172,332.72 | 13,236 | BFNF1D6 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $171,354.50 | 4,405 | BDD19F8 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $169,497.57 | 5,259 | BTZRLN8 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $161,533.80 | 2,580 | BGKG6G7 |
| 0.19% | TNGX | TANGO THERAPEUTICS INC | -- | $157,344.82 | 5,666 | BP2P6L0 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $157,040.80 | 4,835 | BP8JSP4 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $156,306.00 | 7,170 | 2713317 |
| 0.19% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $153,555.57 | 3,279 | BQS9486 |
| 0.18% | TVTX | TRAVERE THERAPEUTICS INC | -- | $150,505.18 | 3,881 | BLFGJD5 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $146,414.40 | 4,512 | BKY5JZ8 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $140,484.00 | 2,036 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $134,287.23 | 6,671 | BD2B4V0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $133,029.25 | 6,925 | BN15WD1 |
| 0.16% | ALMS | ALUMIS INC | -- | $132,868.62 | 5,319 | BPLQG36 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $131,537.34 | 4,286 | BK6L288 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $126,319.20 | 7,519 | BN2R582 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $121,984.20 | 5,213 | BKX9VD3 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $120,260.12 | 3,002 | BL55460 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $118,487.52 | 2,568 | BFXC933 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $118,477.44 | 2,412 | B72ZBG4 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $117,611.85 | 3,695 | BK0VHF6 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $115,472.90 | 1,790 | BMH5RL1 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $114,633.22 | 2,498 | BMFD115 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $113,678.53 | 4,949 | BKS3RS7 |
| 0.14% | VCYT | VERACYTE INC | -- | $112,090.95 | 3,345 | BFTWZY0 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $110,942.48 | 1,606 | BMGJZJ8 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $108,015.60 | 10,020 | B9NSBM2 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $99,984.96 | 4,194 | BV2DHY6 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,966.50 | 4,065 | BJ62Z18 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $95,837.40 | 3,330 | BP9N0G0 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $93,395.54 | 4,346 | BLB0YH0 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $92,038.17 | 6,477 | BJ5FZ74 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $91,178.12 | 4,409 | B8DPDT7 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,544.74 | 10,553 | 2100362 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $89,531.00 | 3,550 | BMX9K07 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $89,050.50 | 3,150 | BPCQZY9 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,481.26 | 5,593 | BFWLC09 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $86,577.63 | 3,711 | BN7Q7R7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $85,535.22 | 2,402 | BJQ05Z6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $85,352.56 | 9,158 | BNZB1X8 |
| 0.10% | GRAL | GRAIL INC | -- | $83,619.90 | 1,638 | BSLSSX7 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $82,369.05 | 2,245 | BMVNDH9 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $82,013.40 | 1,932 | BRXB0C0 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $81,300.98 | 4,622 | BPCK358 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $78,845.66 | 5,393 | BJH9ZN0 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,588.40 | 2,696 | BMZ2X38 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $78,523.41 | 1,879 | BQKXDX4 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $78,228.76 | 2,434 | BKSGZN7 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $78,174.04 | 21,959 | BM9FJ13 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $76,075.39 | 4,969 | BYZM6C2 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,383.42 | 943 | BCDWBX6 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $74,408.73 | 15,279 | BWJDYK1 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $74,121.70 | 2,006 | BR3T9B6 |
| 0.09% | INVA | INNOVIVA INC | -- | $73,545.15 | 3,115 | BDDXF67 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $73,305.54 | 2,709 | BBC9WC7 |
| 0.09% | VCEL | VERICEL CORP | -- | $71,952.79 | 2,137 | BSBMN89 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $71,666.84 | 11,522 | BNC1BX1 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $71,597.13 | 6,611 | BK4PZ38 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,119.44 | 4,326 | BMVLGP2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $67,036.01 | 3,209 | BP7KZP7 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $64,778.56 | 2,464 | BCBVTX1 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $64,121.00 | 17,330 | BF0DMK7 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $62,757.12 | 1,888 | BQXJKH2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $61,588.15 | 2,665 | BQB42F1 |
| 0.07% | HROW | HARROW INC | -- | $61,581.45 | 1,561 | BHNDW86 |
| 0.07% | ARDX | ARDELYX INC | -- | $61,483.36 | 10,316 | BN89V40 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $60,473.94 | 1,167 | BDRW1L7 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $59,561.50 | 3,475 | BYP80F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $59,250.26 | 14,887 | BKM5C84 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $58,545.01 | 4,787 | BYSS4X4 |
| 0.07% | NVAX | NOVAVAX INC | -- | $58,173.48 | 6,852 | BJDQXG4 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $58,132.80 | 7,920 | BYZG9R0 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,059.73 | 3,371 | BMZ4LN0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,434.88 | 1,844 | BLCD809 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,896.50 | 2,610 | BP6C0S2 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $53,843.24 | 1,738 | BMGTLY5 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $51,996.56 | 2,024 | BSRK699 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,372.88 | 611 | BNSP8K3 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,888.46 | 12,754 | BL53SR3 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $49,259.04 | 1,968 | BZ7PJQ1 |
| 0.06% | EYPT | EYEPOINT INC | -- | $49,131.02 | 3,482 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $48,774.96 | 13,896 | BPNTJ34 |
| 0.06% | SEPN | SEPTERNA INC | -- | $48,555.60 | 1,882 | BQNKXX2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $46,896.03 | 867 | BL95N25 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $46,868.92 | 2,293 | BQB42H3 |
| 0.06% | QURE | UNIQURE NV | -- | $45,736.45 | 2,621 | BJFSR88 |
| 0.05% | SVRA | SAVARA INC | -- | $45,207.36 | 8,562 | BYXGN81 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $44,890.49 | 4,223 | BKVDFF7 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,448.72 | 1,336 | BX7RSN3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $43,040.70 | 5,130 | B8K7T65 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $42,684.32 | 3,314 | BJLKVS6 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,912.64 | 1,701 | B3X26D8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $41,462.20 | 11,206 | BMFJJ97 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $41,327.61 | 2,127 | BD06CS0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,118.09 | 6,981 | BLR7H87 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,588.56 | 3,933 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,468.68 | 1,908 | BNFWZS4 |
| 0.05% | GERN | GERON CORP | -- | $40,284.00 | 26,856 | 2370381 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,577.60 | 2,560 | BMFX8Y7 |
| 0.05% | OMER | OMEROS CORP | -- | $39,528.06 | 2,981 | B4NB858 |
| 0.05% | XNCR | XENCOR INC | -- | $38,927.07 | 3,087 | BGCYWN8 |
| 0.05% | ANNX | ANNEXON INC | -- | $37,745.60 | 6,088 | BMVV9R5 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $36,713.25 | 3,969 | BMC3HS7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $35,843.13 | 8,091 | BZ0QMB7 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $35,827.47 | 1,827 | BT9K6D8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $35,612.18 | 2,201 | BQS7491 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,450.46 | 2,133 | BMNDK09 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,350.92 | 2,486 | BM90J52 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $35,218.04 | 1,441 | BD9GVY0 |
| 0.04% | MNKD | MANNKIND CORP | -- | $35,000.10 | 12,963 | BF081J4 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,669.67 | 3,661 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $34,435.62 | 3,386 | BFYQFJ2 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $33,924.52 | 7,127 | BYWVTY5 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $32,614.40 | 4,160 | BMCR7V2 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,829.55 | 2,395 | BMFK3H6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,725.00 | 1,250 | BKLCWZ3 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $28,933.14 | 7,594 | BPBJFM7 |
| 0.03% | ARVN | ARVINAS INC | -- | $28,589.04 | 2,692 | BDZ30Q0 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,863.22 | 6,846 | B3MZ6K5 |
| 0.03% | PSNL | PERSONALIS INC | -- | $27,468.48 | 4,402 | BJQ0608 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,764.80 | 3,280 | BQHN6C7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,532.33 | 1,749 | BRJJYT3 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $26,529.58 | 1,127 | BGL0JK3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,701.85 | 765 | BQD3J33 |
| 0.03% | ABSI | ABSCI CORP | -- | $24,671.40 | 6,326 | BN94K69 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,593.13 | 2,367 | BLFBZ32 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,457.32 | 3,314 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,146.21 | 2,263 | B91XRN2 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,333.13 | 2,403 | BSMLR16 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,661.44 | 6,158 | BMCWKZ2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,268.54 | 5,131 | BYVQJ96 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $21,979.65 | 12,705 | B4N8MH9 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,935.60 | 9,455 | BFZNYB7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,863.24 | 791 | BPBPCG8 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,532.00 | 3,076 | BP0TQC5 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,371.07 | 894 | BTNMG41 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,150.24 | 5,072 | BYV2W40 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $21,091.53 | 2,801 | BJDX8Z9 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,068.84 | 1,612 | BP81RK8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $21,047.98 | 2,273 | BRCFFK6 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,935.20 | 2,145 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $20,871.19 | 4,567 | BMXNGZ6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,872.24 | 2,671 | BP81R42 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $19,839.00 | 1,167 | BS2CR64 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,707.24 | 2,427 | B2Q9833 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,404.30 | 2,130 | BZ0G875 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $19,316.59 | 3,071 | BQ6C357 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,307.52 | 10,056 | BBNBTD2 |
| 0.02% | IVVD | INVIVYD INC | -- | $18,534.63 | 11,657 | BM8NHS1 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $18,133.20 | 3,285 | BLN9Z50 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,039.84 | 624 | B292NQ7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,960.47 | 5,267 | BFY7DC4 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,251.50 | 651 | BS2F741 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,929.66 | 2,497 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,845.15 | 1,281 | BPRBTY7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,718.88 | 4,568 | BDFKQ07 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $16,311.92 | 7,031 | BN4JN37 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,179.28 | 1,222 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,529.14 | 2,139 | B7F2TY6 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $15,266.75 | 1,975 | BL5B6Z1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,968.35 | 2,697 | BMVBZF5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,499.42 | 1,282 | BM7V485 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $13,650.00 | 3,900 | BYTYP72 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $13,553.10 | 4,107 | BZ8FPH3 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,439.18 | 2,726 | BDRJH21 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,382.16 | 3,014 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,082.00 | 8,440 | BFMLGR4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,980.01 | 2,463 | BMF7DT9 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,979.05 | 1,315 | BQV0J03 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,807.60 | 4,105 | BKX9NQ0 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,670.24 | 4,048 | BK5MWR1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $12,151.58 | 4,234 | BZC0D70 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,135.54 | 4,722 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,444.16 | 6,288 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,539.90 | 1,195 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,217.60 | 2,480 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,046.25 | 2,375 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,603.64 | 1,948 | BKDQKM6 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,155.59 | 3,799 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $8,961.40 | 6,055 | BN13S71 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,844.75 | 3,931 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,232.02 | 1,574 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,031.92 | 8,221 | BNR5QT9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,712.55 | 1,305 | BP2NYN2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,547.40 | 2,396 | BKTV702 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,048.76 | 2,252 | BP7L561 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,649.86 | 3,122 | BPTK6Z2 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $6,463.50 | 3,475 | BDDVW37 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,319.47 | 9,119 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,351.08 | 8,120 | BMYTJP4 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,918.92 | 916 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,659.34 | 2,894 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,480.20 | 2,620 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,889.77 | 4,104 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,674.37 | 9,736 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 37.62% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,079,216 | -- | 5,140 | -- |
| 29.84% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,651,744 | -- | 4,077 | -- |
| 27.10% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,384,291 | -- | 3,702 | -- |
| 19.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,956,819 | -- | 2,639 | -- |
| 16.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,308,435 | -- | 2,201 | -- |
| 4.63% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,827,460 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,719,890.01 | 28,719,890 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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