BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,329,165
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/22/2026- NAV
- NAV Change
- Market Price $81.97
- Market Price Change $-0.32
- Trading Volume (M) 6,034
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,329,165
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/22/2026- NAV
- NAV Change
- Market Price $81.97
- Market Price Change $-0.32
- Trading Volume (M) 6,034
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/22/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.81% | GILD | GILEAD SCIENCES INC | -- | $3,431,823.12 | 25,542 | 2369174 |
| 4.66% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,327,119.64 | 7,657 | 2931034 |
| 4.66% | AMGN | AMGEN INC | -- | $3,326,157.90 | 9,803 | 2023607 |
| 3.44% | REGN | REGENERON PHARMACEUTICALS | -- | $2,453,299.20 | 3,840 | 2730190 |
| 2.05% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,458,694.80 | 4,904 | B00FWN1 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,110,328.56 | 7,326 | BL71K91 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,051,148.00 | 5,425 | 2455965 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $920,856.60 | 1,620 | 2430412 |
| 1.21% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $863,116.50 | 15,837 | BMVP7Y0 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $846,783.00 | 1,050 | BDVLM39 |
| 1.19% | INSM | INSMED INC | -- | $846,520.32 | 7,968 | 2614487 |
| 1.14% | ILMN | ILLUMINA INC | -- | $816,349.73 | 5,653 | 2613990 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $792,741.60 | 26,460 | BMW4NZ9 |
| 1.00% | INCY | INCYTE CORP | -- | $715,000.44 | 7,359 | 2471950 |
| 0.99% | VTRS | VIATRIS INC | -- | $708,707.25 | 42,565 | BMWS3X9 |
| 0.96% | MRNA | MODERNA INC | -- | $684,448.00 | 14,600 | BGSXTS3 |
| 0.82% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $581,670.40 | 3,712 | 2623911 |
| 0.81% | GH | GUARDANT HEALTH INC | -- | $576,907.50 | 4,850 | BFXC911 |
| 0.79% | ASND | ASCENDIS PHARMA A/S | -- | $562,285.80 | 2,276 | BWXJHM8 |
| 0.76% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $545,613.25 | 2,275 | B4Q5ZN4 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $495,383.04 | 7,167 | BK1KWG8 |
| 0.68% | EXEL | EXELIXIS INC | -- | $481,440.00 | 9,600 | 2576941 |
| 0.67% | SMMT | SUMMIT THERAPEUTICS INC | -- | $476,395.68 | 28,664 | BMTVQS7 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $461,596.04 | 6,109 | BDJ0LS6 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $454,872.80 | 1,051 | BDCBC61 |
| 0.63% | AXSM | AXSOME THERAPEUTICS INC | -- | $445,983.30 | 1,890 | BYZR4X4 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $438,119.22 | 847 | BD59BS7 |
| 0.56% | SNY | SANOFI-ADR | -- | $400,691.63 | 9,047 | 2964557 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $388,185.82 | 4,213 | BK6H543 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $388,091.10 | 5,178 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $384,579.90 | 7,110 | 2437071 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $366,405.25 | 1,181 | BYYWPW6 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $353,523.24 | 1,029 | BQ721R4 |
| 0.49% | CYTK | CYTOKINETICS INC | -- | $350,307.82 | 4,553 | BBBSBJ5 |
| 0.45% | KRYS | KRYSTAL BIOTECH INC | -- | $323,406.00 | 1,080 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $298,148.48 | 4,364 | 2975098 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $296,660.32 | 6,424 | BSLSJJ0 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $277,039.29 | 2,271 | BLC89B2 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $276,234.60 | 2,705 | BMVBZD3 |
| 0.38% | IBRX | IMMUNITYBIO INC | -- | $274,417.76 | 38,008 | BNSP0B8 |
| 0.36% | IMVT | IMMUNOVANT INC | -- | $256,910.45 | 7,523 | BJRFSB7 |
| 0.35% | PCVX | VAXCYTE INC | -- | $251,683.30 | 5,321 | BKPVGH6 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $238,011.13 | 3,017 | BMPRZV5 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $234,187.59 | 2,361 | BDCBCD8 |
| 0.32% | ALKS | ALKERMES PLC | -- | $226,798.40 | 6,163 | B3P6D26 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $221,883.84 | 2,526 | BF2YWG4 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $220,021.22 | 2,231 | BJDX8Y8 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $215,115.25 | 2,905 | BQBBDY8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $210,696.22 | 3,062 | B17VCN9 |
| 0.28% | CGON | CG ONCOLOGY INC | -- | $200,652.75 | 3,123 | BRBCSP4 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $196,085.34 | 6,002 | BLR6XK8 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $181,594.49 | 3,773 | BFZQ0L8 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $178,778.00 | 3,550 | BDHF4K6 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,814.25 | 4,423 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,538.72 | 4,624 | BTZRLN8 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $168,786.88 | 736 | 2501578 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $166,518.58 | 3,074 | BRJ3GY4 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $164,592.48 | 2,028 | BM9HHL5 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $162,202.05 | 10,431 | BT18HP9 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $151,461.87 | 3,409 | BLFGJD5 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $150,690.88 | 4,252 | BP8JSP4 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $144,469.44 | 11,632 | BFNF1D6 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $142,489.60 | 3,872 | BDD19F8 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $137,251.62 | 2,266 | BGKG6G7 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $132,993.30 | 6,303 | 2713317 |
| 0.19% | VCYT | VERACYTE INC | -- | $132,298.14 | 2,938 | BFTWZY0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $129,688.20 | 3,966 | BKY5JZ8 |
| 0.18% | ERAS | ERASCA INC | -- | $128,630.56 | 11,444 | BNLYBF3 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $112,867.20 | 2,880 | BQS9486 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $109,286.32 | 5,863 | BD2B4V0 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $108,431.29 | 1,789 | BKVF0J2 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $107,886.88 | 3,767 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $105,731.19 | 6,087 | BN15WD1 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $103,031.68 | 4,351 | BKS3RS7 |
| 0.14% | ALMS | ALUMIS INC | -- | $102,921.48 | 4,674 | BPLQG36 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $102,205.20 | 2,120 | B72ZBG4 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $100,754.72 | 4,978 | BP2P6L0 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $97,934.98 | 1,573 | BMH5RL1 |
| 0.14% | GRAL | GRAIL INC | -- | $96,686.41 | 1,439 | BSLSSX7 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $95,684.82 | 4,587 | BKX9VD3 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $94,458.60 | 3,246 | BK0VHF6 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $94,283.02 | 1,411 | BMGJZJ8 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $91,693.14 | 3,122 | BMX9K07 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $91,221.84 | 2,196 | BMFD115 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $90,401.52 | 1,698 | BRXB0C0 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $89,729.44 | 2,636 | BL55460 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $89,379.18 | 6,606 | BN2R582 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $87,311.25 | 2,925 | BP9N0G0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $83,525.69 | 3,571 | BJ62Z18 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $82,912.50 | 3,685 | BV2DHY6 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $81,698.65 | 2,255 | BFXC933 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $79,004.96 | 5,692 | BJ5FZ74 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $76,856.59 | 9,271 | 2100362 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $75,593.64 | 4,209 | BYSS4X4 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $74,791.08 | 4,914 | BFWLC09 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $72,553.20 | 8,805 | B9NSBM2 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $70,837.26 | 2,766 | BPCQZY9 |
| 0.10% | PHVS | PHARVARIS NV | -- | $70,252.56 | 2,367 | BMZ2X38 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,657.60 | 830 | BCDWBX6 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $67,905.63 | 1,651 | BQKXDX4 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $67,004.46 | 4,742 | BJH9ZN0 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $66,538.08 | 1,764 | BR3T9B6 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $66,535.00 | 3,802 | BMVLGP2 |
| 0.09% | OCUL | OCULAR THERAPEUTIX INC | -- | $66,243.27 | 8,049 | BNZB1X8 |
| 0.09% | VCEL | VERICEL CORP | -- | $65,118.75 | 1,875 | BSBMN89 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,100.00 | 3,875 | B8DPDT7 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $65,024.34 | 3,261 | BN7Q7R7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $64,521.00 | 2,140 | BKSGZN7 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $64,095.78 | 1,974 | BMVNDH9 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $63,923.73 | 2,379 | BBC9WC7 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $62,603.52 | 15,232 | BF0DMK7 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $61,936.74 | 2,111 | BJQ05Z6 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,540.40 | 2,740 | BDDXF67 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $61,083.33 | 1,023 | BDRW1L7 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $60,951.24 | 2,166 | BCBVTX1 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $58,286.80 | 11,209 | BL53SR3 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $58,083.97 | 19,297 | BM9FJ13 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $58,013.28 | 13,429 | BWJDYK1 |
| 0.08% | QURE | UNIQURE NV | -- | $55,757.95 | 2,305 | BJFSR88 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,602.72 | 10,128 | BNC1BX1 |
| 0.08% | NVAX | NOVAVAX INC | -- | $55,471.83 | 6,023 | BJDQXG4 |
| 0.08% | PGEN | PRECIGEN INC | -- | $55,459.20 | 13,080 | BKM5C84 |
| 0.08% | ARDX | ARDELYX INC | -- | $55,393.26 | 9,066 | BN89V40 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $55,121.22 | 4,059 | BPCK358 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $55,049.40 | 4,369 | BYZM6C2 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $54,408.84 | 537 | BNSP8K3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $53,393.90 | 5,810 | BK4PZ38 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $53,006.58 | 2,818 | BP7KZP7 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,807.30 | 1,658 | BQXJKH2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $50,796.24 | 2,343 | BQB42F1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $50,743.28 | 2,294 | BP6C0S2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,097.30 | 1,870 | BD06CS0 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $49,979.70 | 1,730 | BZ7PJQ1 |
| 0.07% | SEPN | SEPTERNA INC | -- | $46,992.52 | 1,657 | BQNKXX2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,733.43 | 1,621 | BLCD809 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $45,836.84 | 1,778 | BSRK699 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $45,675.10 | 3,455 | BRXYZ57 |
| 0.06% | HROW | HARROW INC | -- | $45,210.00 | 1,370 | BHNDW86 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $44,404.80 | 6,960 | BYZG9R0 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $41,181.47 | 3,487 | BMC3HS7 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $40,816.71 | 1,527 | BMGTLY5 |
| 0.06% | ALVO | ALVOTECH SA | -- | $40,781.40 | 12,210 | BPNTJ34 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $40,520.16 | 2,962 | BMZ4LN0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,930.04 | 1,172 | BX7RSN3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $39,591.66 | 3,062 | BMGS7L1 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $38,510.94 | 3,054 | BYP80F1 |
| 0.05% | MNKD | MANNKIND CORP | -- | $38,494.82 | 11,389 | BF081J4 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $37,969.46 | 6,134 | BLR7H87 |
| 0.05% | SVRA | SAVARA INC | -- | $37,770.48 | 7,524 | BYXGN81 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $37,617.51 | 1,983 | BQB42H3 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $36,202.50 | 3,218 | BYZD465 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $35,989.80 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,908.25 | 1,495 | B3X26D8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $32,992.96 | 2,912 | BJLKVS6 |
| 0.05% | PSNL | PERSONALIS INC | -- | $32,770.43 | 3,869 | BJQ0608 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $32,684.52 | 2,251 | BMFX8Y7 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $32,329.28 | 992 | BGL0JK3 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,928.50 | 7,110 | BZ0QMB7 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $30,875.52 | 3,711 | BKVDFF7 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,873.57 | 1,677 | BNFWZS4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,693.75 | 1,875 | BMNDK09 |
| 0.04% | XNCR | XENCOR INC | -- | $30,661.41 | 2,711 | BGCYWN8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,240.40 | 2,185 | BM90J52 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,236.43 | 9,849 | BMFJJ97 |
| 0.04% | GERN | GERON CORP | -- | $30,210.56 | 23,602 | 2370381 |
| 0.04% | OMER | OMEROS CORP | -- | $30,048.12 | 2,622 | B4NB858 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $29,396.80 | 1,934 | BQS7491 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $29,028.64 | 3,656 | BMCR7V2 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,403.19 | 5,349 | BMVV9R5 |
| 0.04% | ABSI | ABSCI CORP | -- | $28,361.10 | 5,561 | BN94K69 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,489.00 | 2,975 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,642.44 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,377.38 | 763 | BL95N25 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,804.00 | 5,410 | BMCWKZ2 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,629.76 | 6,028 | B3MZ6K5 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $23,616.09 | 1,269 | BD9GVY0 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $23,556.40 | 6,265 | BYWVTY5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,229.78 | 2,911 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,091.85 | 2,105 | BMFK3H6 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,165.00 | 1,100 | BKLCWZ3 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $22,010.88 | 1,536 | BRJJYT3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,628.93 | 2,707 | BP0TQC5 |
| 0.03% | ARVN | ARVINAS INC | -- | $21,479.67 | 2,363 | BDZ30Q0 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $20,892.49 | 2,083 | BLFBZ32 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,180.16 | 693 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,154.68 | 4,459 | BYV2W40 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,818.81 | 6,673 | BPBJFM7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $19,551.87 | 1,989 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,494.72 | 672 | BQD3J33 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $19,065.60 | 2,880 | BQHN6C7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,585.32 | 4,511 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,311.04 | 2,112 | BSMLR16 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $17,852.40 | 2,349 | BP81R42 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,575.14 | 1,023 | BS2CR64 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,714.89 | 1,997 | BRCFFK6 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,709.22 | 2,134 | B2Q9833 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,616.00 | 8,308 | BFZNYB7 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,211.00 | 1,885 | BKLXFX5 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,188.48 | 2,464 | BJDX8Z9 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,822.41 | 571 | BS2F741 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,578.64 | 1,124 | BPRBTY7 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,064.52 | 548 | B292NQ7 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $14,990.23 | 3,053 | BDDVW37 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,954.40 | 1,072 | B9L5200 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,597.73 | 2,397 | BDRJH21 |
| 0.02% | OABI | OMNIAB INC | -- | $14,103.30 | 5,322 | BN13S71 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,848.30 | 4,014 | BMXNGZ6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,781.67 | 2,697 | BQ6C357 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,741.02 | 787 | BTNMG41 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,618.86 | 11,163 | B4N8MH9 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,531.34 | 2,186 | B12W3P6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,429.90 | 4,631 | BFY7DC4 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,303.32 | 1,879 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,983.05 | 3,557 | BK5MWR1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $12,865.93 | 2,387 | BMVBZF5 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,848.04 | 3,609 | BKX9NQ0 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,769.38 | 2,889 | BLN9Z50 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,603.80 | 7,414 | BFMLGR4 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,588.75 | 1,125 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,383.28 | 2,646 | 2107437 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,893.55 | 1,873 | BZ0G875 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,878.48 | 4,013 | BDFKQ07 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,425.60 | 6,176 | BN4JN37 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,268.40 | 10,244 | BM8NHS1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,763.20 | 1,736 | BL5B6Z1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $10,530.43 | 3,721 | BZC0D70 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,966.36 | 3,611 | BZ8FPH3 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,288.96 | 1,416 | BP81RK8 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,233.07 | 3,426 | BYTYP72 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,136.30 | 2,165 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,895.25 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,742.90 | 1,158 | BQV0J03 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,481.34 | 2,089 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,319.09 | 3,341 | B5LL2C2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,280.20 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,132.23 | 1,147 | BP2NYN2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,785.05 | 1,711 | BKDQKM6 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,706.09 | 1,981 | BP7L561 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,663.80 | 7,230 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,492.80 | 7,136 | BMYTJP4 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,395.56 | 1,052 | BKC9SX3 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,347.27 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,253.40 | 3,454 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,837.91 | 1,387 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,189.27 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,897.45 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,799.40 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,513.88 | 2,303 | BLBR8D5 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,860.56 | 3,608 | BNNXX18 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,836.91 | 2,541 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $3,650.16 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,797.41 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 31.65% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 22,576,075 | -- | 3,832 | -- |
| 29.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,761,505 | -- | 3,524 | -- |
| 27.87% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,877,786 | -- | 3,374 | -- |
| 21.80% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,547,563 | -- | 2,639 | -- |
| 20.76% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,805,239 | -- | 2,513 | -- |
| 5.23% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,729,294 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,007,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $20,649,709.96 | 20,649,710 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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