BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/12/2026- NAV $83.12
- NAV Change $-1.81
- Market Price $83.09
- Market Price Change $-1.78
- Trading Volume (M) 7,505
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/12/2026- NAV $83.12
- NAV Change $-1.81
- Market Price $83.09
- Market Price Change $-1.78
- Trading Volume (M) 7,505
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/12/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 7.04% | GILD | GILEAD SCIENCES INC | -- | $6,142,688.03 | 40,463 | 2369174 |
| 6.26% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,460,729.86 | 11,743 | 2931034 |
| 6.14% | AMGN | AMGEN INC | -- | $5,360,279.52 | 14,739 | 2023607 |
| 4.34% | REGN | REGENERON PHARMACEUTICALS | -- | $3,789,731.40 | 4,836 | 2730190 |
| 2.19% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,908,257.28 | 6,186 | B00FWN1 |
| 1.67% | INSM | INSMED INC | -- | $1,459,653.62 | 9,986 | 2614487 |
| 1.54% | BIIB | BIOGEN INC | -- | $1,342,889.50 | 6,869 | 2455965 |
| 1.30% | ARGX | ARGENX SE - ADR | -- | $1,136,115.02 | 1,363 | BDVLM39 |
| 1.10% | UTHR | UNITED THERAPEUTICS CORP | -- | $959,878.08 | 2,016 | 2430412 |
| 1.06% | INCY | INCYTE CORP | -- | $926,094.00 | 9,192 | 2471950 |
| 1.03% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $896,224.00 | 20,005 | BMVP7Y0 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $881,031.16 | 9,052 | BL71K91 |
| 1.00% | ROIV | ROIVANT SCIENCES LTD | -- | $871,087.00 | 32,564 | BMW4NZ9 |
| 0.98% | VTRS | VIATRIS INC | -- | $851,523.12 | 53,928 | BMWS3X9 |
| 0.94% | ILMN | ILLUMINA INC | -- | $818,703.76 | 7,154 | 2613990 |
| 0.84% | MRNA | MODERNA INC | -- | $733,692.12 | 18,292 | BGSXTS3 |
| 0.79% | BBIO | BRIDGEBIO PHARMA INC | -- | $686,213.32 | 9,022 | BK1KWG8 |
| 0.72% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $627,037.50 | 2,875 | BV9G6B8 |
| 0.71% | GH | GUARDANT HEALTH INC | -- | $622,520.08 | 6,058 | BFXC911 |
| 0.71% | IONS | IONIS PHARMACEUTICALS INC | -- | $620,219.52 | 7,584 | BDJ0LS6 |
| 0.67% | SNY | SANOFI-ADR | -- | $582,701.70 | 12,390 | 2964557 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $574,630.80 | 4,668 | 2623911 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $548,756.76 | 1,319 | BDCBC61 |
| 0.62% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $539,160.30 | 8,995 | 2437071 |
| 0.61% | EXEL | EXELIXIS INC | -- | $536,055.80 | 12,554 | 2576941 |
| 0.59% | RNA | AVIDITY BIOSCIENCES INC | -- | $514,380.05 | 7,055 | BMWHPY1 |
| 0.59% | ONC | BEONE MEDICINES LTD-ADR | -- | $510,623.08 | 1,474 | BYYWPW6 |
| 0.58% | SMMT | SUMMIT THERAPEUTICS INC | -- | $509,943.28 | 34,856 | BMTVQS7 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $503,638.77 | 1,063 | BD59BS7 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $500,667.84 | 4,734 | BK6H543 |
| 0.54% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $473,095.05 | 2,845 | B4Q5ZN4 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $431,738.40 | 2,360 | BYZR4X4 |
| 0.49% | HALO | HALOZYME THERAPEUTICS INC | -- | $423,521.52 | 5,506 | 2975098 |
| 0.47% | TEM | TEMPUS AI INC | -- | $411,013.32 | 8,094 | BSLSJJ0 |
| 0.45% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $396,674.42 | 6,359 | BYQBFJ8 |
| 0.45% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $389,849.32 | 1,171 | BQ721R4 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $372,354.00 | 5,725 | BBBSBJ5 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $367,013.08 | 1,358 | BD6JX35 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $344,228.56 | 2,764 | BLC89B2 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $342,698.06 | 3,382 | BMVBZD3 |
| 0.39% | PCVX | VAXCYTE INC | -- | $336,788.55 | 6,129 | BKPVGH6 |
| 0.35% | IBRX | IMMUNITYBIO INC | -- | $305,301.16 | 46,118 | BNSP0B8 |
| 0.34% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $300,187.50 | 3,125 | BF2YWG4 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $283,063.38 | 3,369 | BMPRZV5 |
| 0.31% | CAI | CARIS LIFE SCIENCES INC | -- | $272,807.15 | 13,211 | BT18HP9 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $265,761.30 | 3,759 | B17VCN9 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $263,906.64 | 7,187 | BLR6XK8 |
| 0.29% | ALKS | ALKERMES PLC | -- | $257,364.99 | 7,731 | B3P6D26 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $245,436.06 | 2,406 | BJDX8Y8 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $239,809.11 | 2,927 | BDCBCD8 |
| 0.26% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $225,413.16 | 3,129 | BQS9486 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $222,848.16 | 4,776 | BFZQ0L8 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $218,325.66 | 4,462 | BDHF4K6 |
| 0.25% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $215,338.97 | 14,719 | BFNF1D6 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $210,427.48 | 8,207 | BJRFSB7 |
| 0.24% | FOLD | AMICUS THERAPEUTICS INC | -- | $207,011.18 | 14,446 | B19FQ48 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $197,293.44 | 5,844 | BTZRLN8 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $195,847.44 | 4,443 | BDD19F8 |
| 0.22% | CGON | CG ONCOLOGY INC | -- | $194,968.74 | 3,777 | BRBCSP4 |
| 0.21% | ACLX | ARCELLX INC | -- | $185,835.55 | 2,707 | BPCJ1Q2 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $185,071.74 | 5,309 | BP8JSP4 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $177,918.77 | 2,567 | BM9HHL5 |
| 0.20% | GRAL | GRAIL INC | -- | $174,999.25 | 1,825 | BSLSSX7 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $173,734.96 | 11,144 | B9NSBM2 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $171,172.81 | 7,921 | 2713317 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $167,481.30 | 922 | 2501578 |
| 0.19% | ERAS | ERASCA INC | -- | $163,526.04 | 13,284 | BNLYBF3 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $159,229.50 | 4,218 | BMDJ0C9 |
| 0.18% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $153,181.85 | 5,735 | BKX9VD3 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $150,581.16 | 3,618 | BRJ3GY4 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $150,544.09 | 4,957 | BKY5JZ8 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $136,450.58 | 2,863 | BGKG6G7 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $133,847.25 | 2,685 | B72ZBG4 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $131,709.06 | 6,867 | BD2B4V0 |
| 0.15% | APLS | APELLIS PHARMACEUTICALS INC | -- | $130,558.05 | 5,921 | BYTQ6X1 |
| 0.15% | VCYT | VERACYTE INC | -- | $130,090.15 | 3,701 | BFTWZY0 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $129,389.60 | 4,105 | BK0VHF6 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $128,183.40 | 4,189 | BLFGJD5 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $127,944.43 | 4,751 | BK6L288 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $126,677.20 | 1,768 | BMGJZJ8 |
| 0.15% | SYRE | SPYRE THERAPEUTICS INC | -- | $126,573.72 | 3,633 | BQBBDY8 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $126,339.84 | 2,991 | BL55460 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $125,741.00 | 1,988 | BMH5RL1 |
| 0.14% | ALMS | ALUMIS INC | -- | $121,993.60 | 4,552 | BPLQG36 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $111,079.92 | 7,148 | BJ5FZ74 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $109,537.25 | 4,517 | BLB0YQ9 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $106,992.00 | 6,687 | BN15WD1 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $106,149.50 | 4,517 | BJ62Z18 |
| 0.12% | MAZE | MAZE THERAPEUTICS INC | -- | $105,981.12 | 2,253 | BSRK699 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $103,221.30 | 3,705 | BP9N0G0 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $100,236.80 | 7,831 | BYZG9R0 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $96,687.45 | 2,697 | BKSGZN7 |
| 0.11% | TXG | 10X GENOMICS INC-CLASS A | -- | $95,499.54 | 5,454 | BKS3RS7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,561.65 | 2,115 | BRXB0C0 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $90,373.50 | 9,975 | BNZB1X8 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,335.63 | 6,173 | BFWLC09 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $87,471.25 | 3,683 | BMZ4LN0 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $86,188.50 | 24,075 | BM9FJ13 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $86,039.80 | 4,070 | BN7Q7R7 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $85,364.40 | 4,906 | B8DPDT7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $85,305.75 | 2,675 | BJQ05Z6 |
| 0.09% | HROW | HARROW INC | -- | $81,706.08 | 1,734 | BHNDW86 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $81,187.68 | 3,504 | BPCQZY9 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $80,987.83 | 2,737 | BBC9WC7 |
| 0.09% | MNKD | MANNKIND CORP | -- | $80,948.14 | 14,378 | BF081J4 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $80,688.40 | 1,052 | BCDWBX6 |
| 0.09% | VCEL | VERICEL CORP | -- | $80,440.96 | 2,368 | BSBMN89 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $79,897.02 | 6,306 | BP2P6L0 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $79,876.00 | 2,102 | BQXJKH2 |
| 0.09% | PHVS | PHARVARIS NV | -- | $79,773.40 | 2,999 | BMZ2X38 |
| 0.09% | ARDX | ARDELYX INC | -- | $79,752.77 | 11,377 | BN89V40 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $78,667.60 | 2,090 | BQKXDX4 |
| 0.09% | INVA | INNOVIVA INC | -- | $78,562.44 | 3,501 | BDDXF67 |
| 0.09% | PGEN | PRECIGEN INC | -- | $78,527.58 | 16,567 | BKM5C84 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $76,631.10 | 2,730 | BCBVTX1 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $75,477.64 | 2,779 | BMFD115 |
| 0.09% | RAPT | RAPT THERAPEUTICS INC | -- | $74,992.54 | 1,297 | BTJZB49 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $74,852.76 | 4,612 | BV2DHY6 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $74,654.58 | 4,746 | BMVLGP2 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,994.88 | 2,267 | BKVF0J2 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $72,945.81 | 2,499 | BMVNDH9 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,347.94 | 5,142 | BPCK358 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $71,493.15 | 8,115 | BN2R582 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $71,192.52 | 3,942 | BMX9K07 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $71,150.40 | 1,296 | BDRW1L7 |
| 0.08% | ALVO | ALVOTECH SA | -- | $69,029.76 | 14,656 | BPNTJ34 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $67,034.40 | 9,858 | 2100362 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $67,014.40 | 1,480 | BX7RSN3 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $65,694.79 | 5,243 | BYSS4X4 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $65,683.76 | 6,004 | BJH9ZN0 |
| 0.08% | ZBIO | ZENAS BIOPHARMA INC | -- | $65,614.43 | 2,513 | BQB42H3 |
| 0.08% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $65,603.72 | 3,497 | BYP80F1 |
| 0.07% | QURE | UNIQURE NV | -- | $65,253.29 | 2,917 | BJFSR88 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $64,946.97 | 2,043 | BLCD809 |
| 0.07% | NVAX | NOVAVAX INC | -- | $64,067.78 | 7,609 | BJDQXG4 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $63,015.26 | 5,423 | BYZM6C2 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $62,429.04 | 2,232 | BR3T9B6 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $60,877.90 | 17,005 | BWJDYK1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,636.25 | 12,825 | BNC1BX1 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $59,287.60 | 2,152 | BNFWZS4 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $56,406.50 | 3,049 | BP7KZP7 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,916.91 | 681 | BNSP8K3 |
| 0.06% | SVRA | SAVARA INC | -- | $55,542.41 | 9,527 | BYXGN81 |
| 0.06% | KOD | KODIAK SCIENCES INC | -- | $54,648.00 | 2,484 | BFXC933 |
| 0.06% | SEPN | SEPTERNA INC | -- | $53,992.96 | 2,096 | BQNKXX2 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $53,683.79 | 7,769 | BLR7H87 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $53,007.36 | 5,712 | B8K7T65 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $52,877.00 | 4,807 | BLB0YH0 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,426.76 | 3,876 | BMGS7L1 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,222.94 | 6,514 | BK4PZ38 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,163.14 | 959 | BL95N25 |
| 0.06% | GERN | GERON CORP | -- | $48,719.07 | 29,889 | 2370381 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $47,268.88 | 12,472 | BMFJJ97 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $46,839.24 | 18,587 | BF0DMK7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $46,694.40 | 4,560 | BKVDFF7 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,540.13 | 3,341 | BMG99Y1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,036.20 | 2,373 | BMNDK09 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $44,428.02 | 4,326 | BRXYZ57 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $44,300.32 | 2,192 | BZ7PJQ1 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $43,607.30 | 1,367 | BKLCWZ3 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $43,589.04 | 2,904 | BP6C0S2 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $43,337.86 | 1,933 | BMGTLY5 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,200.30 | 2,014 | B3X26D8 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $43,076.19 | 7,933 | BYWVTY5 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $41,204.10 | 14,015 | BL53SR3 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $40,772.68 | 4,628 | BMCR7V2 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,038.62 | 3,331 | BJLKVS6 |
| 0.04% | XNCR | XENCOR INC | -- | $38,857.28 | 3,344 | BGCYWN8 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,779.44 | 2,296 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $38,056.20 | 11,193 | BBNBTD2 |
| 0.04% | OMER | OMEROS CORP | -- | $37,980.80 | 3,320 | B4NB858 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $36,974.08 | 2,816 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,110.05 | 9,005 | BZ0QMB7 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $36,063.90 | 2,565 | BQB42F1 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $35,789.04 | 2,367 | BD06CS0 |
| 0.04% | ARVN | ARVINAS INC | -- | $35,587.85 | 3,007 | BDZ30Q0 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,172.63 | 6,777 | BMVV9R5 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $35,114.37 | 7,617 | B3MZ6K5 |
| 0.04% | PSNL | PERSONALIS INC | -- | $34,885.62 | 4,158 | BJQ0608 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $34,405.41 | 1,833 | BD9GVY0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,479.26 | 1,679 | BT9K6D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,673.48 | 4,074 | BYZD465 |
| 0.04% | UPB | UPSTREAM BIO INC | -- | $32,384.00 | 2,530 | BRCFFK6 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $32,334.54 | 2,766 | BM90J52 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $29,310.54 | 3,673 | BDDVW37 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $29,087.00 | 850 | BQD3J33 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,060.64 | 8,452 | BPBJFM7 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,739.84 | 3,769 | BFYQFJ2 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $27,519.24 | 2,534 | BJDX8Z9 |
| 0.03% | CRMD | CORMEDIX INC | -- | $27,151.04 | 3,689 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,803.35 | 2,667 | BMFK3H6 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $26,010.24 | 14,136 | B4N8MH9 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $25,810.20 | 4,412 | BMC3HS7 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $25,424.75 | 7,823 | BN4JN37 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $25,202.34 | 993 | BTNMG41 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $25,141.84 | 10,837 | BJ0CK86 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $25,038.00 | 2,675 | BKLXFX5 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $23,685.86 | 1,426 | BM7V485 |
| 0.03% | KMDA | KAMADA LTD | -- | $23,147.57 | 2,701 | B2Q9833 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,632.11 | 677 | B292NQ7 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $22,449.69 | 3,417 | BQ6C357 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,398.04 | 3,353 | 2107437 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $22,329.02 | 4,886 | BFY7DC4 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,302.00 | 2,520 | B91XRN2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,179.84 | 3,648 | BQHN6C7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,142.40 | 2,636 | BLFBZ32 |
| 0.03% | PEPG | PEPGEN INC | -- | $21,857.01 | 3,219 | BMTX3D7 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,420.00 | 5,712 | BYVQJ96 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $21,088.24 | 1,256 | BGL0JK3 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,505.80 | 6,790 | BMCWKZ2 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,893.96 | 876 | BPBPCG8 |
| 0.02% | IVVD | INVIVYD INC | -- | $19,851.75 | 12,975 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,789.50 | 2,370 | BZ0G875 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,332.00 | 1,790 | BP81RK8 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $19,001.05 | 1,465 | BQV0J03 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,697.84 | 1,351 | B9L5200 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,045.64 | 10,522 | BFZNYB7 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $17,045.28 | 5,073 | BYV2W40 |
| 0.02% | ABSI | ABSCI CORP | -- | $17,039.22 | 7,041 | BN94K69 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,934.04 | 2,767 | B12W3P6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,445.00 | 5,060 | BDFKQ07 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,397.36 | 4,183 | BYTYP72 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,381.23 | 2,973 | BP81R42 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,100.16 | 1,082 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,041.20 | 2,359 | B7F2TY6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $15,839.14 | 3,658 | BLN9Z50 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $15,772.32 | 4,868 | BKRRKY7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $15,095.36 | 2,051 | BSMLR16 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,994.08 | 3,023 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $14,392.00 | 2,570 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,928.48 | 2,648 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,773.93 | 4,701 | BZC0D70 |
| 0.01% | EOLS | EVOLUS INC | -- | $12,989.80 | 3,035 | BDRJH21 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,960.96 | 9,392 | BFMLGR4 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,865.68 | 4,008 | BMXNGZ6 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $12,844.95 | 4,507 | BK5MWR1 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,513.32 | 1,019 | BTXQTX3 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,325.00 | 725 | BS2F741 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,278.00 | 1,754 | 2517058 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,609.76 | 2,166 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $11,390.60 | 6,740 | BN13S71 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,374.59 | 5,659 | BRK0149 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,312.23 | 789 | BRJJYT3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,100.08 | 2,644 | BPRB2N7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,983.46 | 2,199 | BL5B6Z1 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,536.10 | 1,330 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,435.78 | 2,759 | BY7RB53 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,928.02 | 9,156 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,855.68 | 8,768 | BMYTJP4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,304.54 | 4,538 | BKX9NQ0 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,679.28 | 4,571 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,477.80 | 1,452 | BP2NYN2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,651.52 | 4,376 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,842.92 | 2,668 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,708.75 | 4,567 | BNNXX18 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,337.78 | 2,506 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,329.35 | 7,796 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,233.20 | 3,560 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $4,990.22 | 4,229 | B5LL2C2 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,935.25 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $15.62 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 38.10% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 33,247,581 | -- | 5,673 | -- |
| 29.65% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,874,858 | -- | 4,415 | -- |
| 23.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,283,779 | -- | 3,461 | -- |
| 17.72% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,466,308 | -- | 2,639 | -- |
| 16.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,557,904 | -- | 2,484 | -- |
| 4.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,709,804 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,937,831.49 | 25,937,831 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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