BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $85,888,390
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/17/2026- NAV
- NAV Change
- Market Price $89.45
- Market Price Change $+2.73
- Trading Volume (M) 9,637
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $85,888,390
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/17/2026- NAV
- NAV Change
- Market Price $89.45
- Market Price Change $+2.73
- Trading Volume (M) 9,637
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/17/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.73% | GILD | GILEAD SCIENCES INC | -- | $4,065,472.68 | 29,537 | 2369174 |
| 4.69% | AMGN | AMGEN INC | -- | $4,027,325.50 | 11,335 | 2023607 |
| 4.55% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,906,384.80 | 8,854 | 2931034 |
| 3.88% | REGN | REGENERON PHARMACEUTICALS | -- | $3,332,530.80 | 4,440 | 2730190 |
| 2.04% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,755,152.88 | 5,668 | B00FWN1 |
| 1.55% | INSM | INSMED INC | -- | $1,331,527.68 | 9,216 | 2614487 |
| 1.47% | RVMD | REVOLUTION MEDICINES INC | -- | $1,259,193.36 | 8,472 | BL71K91 |
| 1.30% | BIIB | BIOGEN INC | -- | $1,112,516.55 | 6,273 | 2455965 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,102,035.74 | 1,873 | 2430412 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $1,029,036.48 | 1,212 | BDVLM39 |
| 1.07% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $915,800.00 | 18,316 | BMVP7Y0 |
| 1.06% | ROIV | ROIVANT SCIENCES LTD | -- | $912,827.83 | 30,601 | BMW4NZ9 |
| 1.06% | MRNA | MODERNA INC | -- | $907,008.48 | 16,884 | BGSXTS3 |
| 1.02% | ILMN | ILLUMINA INC | -- | $879,361.00 | 6,538 | 2613990 |
| 0.97% | SMMT | SUMMIT THERAPEUTICS INC | -- | $833,722.50 | 33,150 | BMTVQS7 |
| 0.97% | INCY | INCYTE CORP | -- | $832,350.38 | 8,509 | 2471950 |
| 0.84% | VTRS | VIATRIS INC | -- | $722,652.36 | 49,227 | BMWS3X9 |
| 0.75% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $643,226.88 | 2,631 | BV9G6B8 |
| 0.74% | BBIO | BRIDGEBIO PHARMA INC | -- | $636,180.75 | 8,289 | BK1KWG8 |
| 0.73% | MEDP | MEDPACE HOLDINGS INC | -- | $630,967.20 | 1,212 | BDCBC61 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $571,909.00 | 4,292 | 2623911 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $535,198.02 | 2,631 | B4Q5ZN4 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $534,739.73 | 7,063 | BDJ0LS6 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $522,443.64 | 982 | BD59BS7 |
| 0.59% | GH | GUARDANT HEALTH INC | -- | $506,558.16 | 5,606 | BFXC911 |
| 0.59% | SNY | SANOFI-ADR | -- | $502,851.78 | 10,463 | 2964557 |
| 0.58% | BNTX | BIONTECH SE-ADR | -- | $501,323.32 | 4,871 | BK6H543 |
| 0.58% | EXEL | EXELIXIS INC | -- | $498,458.56 | 11,104 | 2576941 |
| 0.52% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $449,304.72 | 8,223 | 2437071 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $442,730.29 | 1,367 | BYYWPW6 |
| 0.48% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $416,295.39 | 5,989 | BYQBFJ8 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $414,890.62 | 7,426 | BSLSJJ0 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $413,321.13 | 2,187 | BYZR4X4 |
| 0.47% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $407,917.50 | 1,191 | BQ721R4 |
| 0.45% | PCVX | VAXCYTE INC | -- | $383,639.55 | 6,153 | BKPVGH6 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $351,294.86 | 5,266 | BBBSBJ5 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $349,637.34 | 5,046 | 2975098 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $343,310.92 | 1,252 | BD6JX35 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $338,468.90 | 43,957 | BNSP0B8 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $336,819.30 | 3,130 | BMVBZD3 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $315,420.00 | 2,625 | BLC89B2 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $306,020.19 | 3,489 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $289,219.42 | 2,729 | BDCBCD8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $265,082.30 | 3,610 | BRBCSP4 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $258,974.80 | 2,920 | BF2YWG4 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $258,515.00 | 6,940 | BLR6XK8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $256,257.34 | 3,538 | B17VCN9 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $255,153.60 | 12,064 | BT18HP9 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $255,027.20 | 8,704 | BJRFSB7 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $252,613.05 | 2,579 | BJDX8Y8 |
| 0.29% | ERAS | ERASCA INC | -- | $251,654.38 | 13,238 | BNLYBF3 |
| 0.29% | ALKS | ALKERMES PLC | -- | $246,026.25 | 7,125 | B3P6D26 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $245,094.57 | 3,357 | BQBBDY8 |
| 0.28% | TERN | TERNS PHARMACEUTICALS INC | -- | $239,399.55 | 4,547 | BMDJ0C9 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $237,990.96 | 4,104 | BDHF4K6 |
| 0.26% | APLS | APELLIS PHARMACEUTICALS INC | -- | $223,559.40 | 5,466 | BYTQ6X1 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $217,975.48 | 4,363 | BFZQ0L8 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $216,116.80 | 2,344 | BM9HHL5 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $212,352.90 | 3,557 | BRJ3GY4 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $202,821.24 | 5,114 | BLB0YQ9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $197,510.64 | 852 | 2501578 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $187,117.32 | 13,452 | BFNF1D6 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $183,557.00 | 4,477 | BDD19F8 |
| 0.20% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $174,781.50 | 5,345 | BTZRLN8 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $170,417.52 | 4,914 | BP8JSP4 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $169,099.00 | 3,332 | BQS9486 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $161,552.79 | 7,287 | 2713317 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $160,796.88 | 3,944 | BLFGJD5 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $157,861.55 | 4,585 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $156,821.82 | 2,622 | BGKG6G7 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $153,393.12 | 5,758 | BP2P6L0 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $143,645.58 | 7,038 | BN15WD1 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $142,595.48 | 2,069 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $139,464.60 | 6,780 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $136,734.84 | 4,356 | BK6L288 |
| 0.16% | ALMS | ALUMIS INC | -- | $135,095.94 | 5,406 | BPLQG36 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $131,182.40 | 5,030 | BKS3RS7 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $129,959.94 | 5,298 | BKX9VD3 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $129,057.30 | 3,051 | BL55460 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $128,063.16 | 7,641 | BN2R582 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $127,332.05 | 3,755 | BK0VHF6 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $125,956.89 | 2,451 | B72ZBG4 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $122,309.56 | 1,819 | BMH5RL1 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $122,151.29 | 2,539 | BMFD115 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $117,189.00 | 2,610 | BFXC933 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $117,128.64 | 1,632 | BMGJZJ8 |
| 0.13% | VCYT | VERACYTE INC | -- | $114,886.20 | 3,399 | BFTWZY0 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $112,114.83 | 10,183 | B9NSBM2 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $103,482.72 | 3,384 | BP9N0G0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,490.11 | 4,131 | BJ62Z18 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $101,887.50 | 10,725 | 2100362 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $96,662.16 | 4,262 | BV2DHY6 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $96,565.55 | 4,481 | B8DPDT7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $95,241.54 | 6,582 | BJ5FZ74 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $94,832.99 | 4,417 | BLB0YH0 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $91,394.74 | 9,307 | BNZB1X8 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $91,371.33 | 3,771 | BN7Q7R7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,228.20 | 5,684 | BFWLC09 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $90,976.07 | 2,441 | BJQ05Z6 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $88,987.80 | 3,201 | BPCQZY9 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $88,138.70 | 1,963 | BRXB0C0 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $87,990.56 | 2,504 | BCBVTX1 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $86,236.92 | 4,697 | BPCK358 |
| 0.10% | GRAL | GRAIL INC | -- | $86,097.15 | 1,665 | BSLSSX7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $84,358.26 | 22,317 | BM9FJ13 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $83,475.63 | 5,481 | BJH9ZN0 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $83,161.40 | 1,910 | BQKXDX4 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $81,147.92 | 2,282 | BMVNDH9 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $80,968.69 | 2,039 | BR3T9B6 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $80,066.86 | 1,186 | BDRW1L7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $78,598.15 | 2,753 | BBC9WC7 |
| 0.09% | PHVS | PHARVARIS NV | -- | $78,309.20 | 2,740 | BMZ2X38 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $77,521.36 | 958 | BCDWBX6 |
| 0.09% | VCEL | VERICEL CORP | -- | $77,496.96 | 2,172 | BSBMN89 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $76,973.96 | 4,396 | BMVLGP2 |
| 0.09% | INVA | INNOVIVA INC | -- | $76,743.84 | 3,166 | BDDXF67 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $76,381.36 | 3,608 | BMX9K07 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $75,497.50 | 5,050 | BYZM6C2 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $75,295.30 | 11,710 | BNC1BX1 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,195.26 | 2,474 | BKSGZN7 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $72,229.25 | 6,719 | BK4PZ38 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $67,982.32 | 17,612 | BF0DMK7 |
| 0.08% | ARDX | ARDELYX INC | -- | $67,621.80 | 10,484 | BN89V40 |
| 0.08% | HROW | HARROW INC | -- | $65,819.00 | 1,586 | BHNDW86 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $65,019.08 | 2,708 | BQB42F1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $64,804.63 | 1,919 | BQXJKH2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $64,502.58 | 3,261 | BP7KZP7 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $62,577.84 | 15,528 | BWJDYK1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $62,417.95 | 4,865 | BYSS4X4 |
| 0.07% | NVAX | NOVAVAX INC | -- | $61,561.76 | 6,964 | BJDQXG4 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $60,287.01 | 8,049 | BYZG9R0 |
| 0.07% | PGEN | PRECIGEN INC | -- | $60,213.42 | 15,129 | BKM5C84 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $59,125.68 | 3,532 | BYP80F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $58,937.30 | 1,874 | BLCD809 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $57,781.13 | 2,057 | BSRK699 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $57,625.32 | 3,426 | BMZ4LN0 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $54,790.83 | 621 | BNSP8K3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $52,837.27 | 3,539 | BMGS7L1 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,344.24 | 1,766 | BMGTLY5 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,977.62 | 12,962 | BL53SR3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $50,980.42 | 14,122 | BPNTJ34 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $50,840.60 | 2,330 | BQB42H3 |
| 0.06% | SVRA | SAVARA INC | -- | $50,291.78 | 8,701 | BYXGN81 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $50,278.67 | 881 | BL95N25 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,986.69 | 1,913 | BQNKXX2 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $48,637.68 | 2,652 | BP6C0S2 |
| 0.05% | QURE | UNIQURE NV | -- | $46,833.12 | 2,664 | BJFSR88 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $46,728.78 | 1,358 | BX7RSN3 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $46,139.00 | 4,292 | BKVDFF7 |
| 0.05% | GERN | GERON CORP | -- | $45,852.24 | 27,293 | 2370381 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $45,622.50 | 5,214 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $45,195.15 | 7,095 | BLR7H87 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $45,080.00 | 2,000 | BZ7PJQ1 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $44,423.92 | 3,368 | BJLKVS6 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $44,364.32 | 1,939 | BNFWZS4 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $44,277.76 | 2,162 | BD06CS0 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,740.88 | 1,729 | B3X26D8 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $41,488.86 | 3,997 | BRXYZ57 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $41,163.64 | 2,602 | BMFX8Y7 |
| 0.05% | XNCR | XENCOR INC | -- | $40,969.22 | 3,137 | BGCYWN8 |
| 0.05% | OMER | OMEROS CORP | -- | $40,723.20 | 3,030 | B4NB858 |
| 0.05% | ANNX | ANNEXON INC | -- | $40,462.98 | 6,187 | BMVV9R5 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $40,085.76 | 11,388 | BMFJJ97 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,812.56 | 8,223 | BZ0QMB7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $38,041.56 | 2,526 | BM90J52 |
| 0.04% | MNKD | MANNKIND CORP | -- | $37,414.16 | 13,174 | BF081J4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $37,354.64 | 2,168 | BMNDK09 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $36,821.02 | 2,237 | BQS7491 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $36,019.28 | 3,721 | BYZD465 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $35,414.16 | 1,464 | BD9GVY0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $34,911.26 | 7,243 | BYWVTY5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $34,822.92 | 3,441 | BFYQFJ2 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,585.04 | 4,228 | BMCR7V2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $34,335.93 | 1,857 | BT9K6D8 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,934.08 | 2,434 | BMFK3H6 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $31,813.50 | 1,270 | BKLCWZ3 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,823.94 | 6,958 | B3MZ6K5 |
| 0.04% | PSNL | PERSONALIS INC | -- | $30,110.02 | 4,474 | BJQ0608 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,096.00 | 2,736 | BDZ30Q0 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $29,480.43 | 1,777 | BRJJYT3 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $29,405.58 | 7,718 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $28,763.79 | 3,333 | BQHN6C7 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $28,670.80 | 1,145 | BGL0JK3 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $26,866.44 | 4,034 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,672.02 | 2,406 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $25,198.11 | 777 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $25,070.00 | 2,300 | B91XRN2 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,889.52 | 3,368 | BJ0LT31 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $24,249.06 | 2,442 | BSMLR16 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $23,726.04 | 804 | BPBPCG8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $23,601.63 | 2,847 | BJDX8Z9 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,076.90 | 2,310 | BRCFFK6 |
| 0.03% | ABSI | ABSCI CORP | -- | $23,015.82 | 6,429 | BN94K69 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,965.51 | 9,609 | BFZNYB7 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,915.62 | 1,638 | BP81RK8 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,868.20 | 2,180 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,528.80 | 5,215 | BYVQJ96 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,276.80 | 4,641 | BMXNGZ6 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,908.75 | 5,155 | BYV2W40 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,825.09 | 909 | BTNMG41 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $21,821.28 | 12,912 | B4N8MH9 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,566.11 | 3,121 | BQ6C357 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,214.62 | 6,258 | BMCWKZ2 |
| 0.02% | KMDA | KAMADA LTD | -- | $20,944.83 | 2,467 | B2Q9833 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $20,848.80 | 10,220 | BBNBTD2 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,613.78 | 11,847 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,545.85 | 2,165 | BZ0G875 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $19,912.62 | 3,126 | BP0TQC5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,792.35 | 2,715 | BP81R42 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,165.86 | 3,339 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,735.50 | 5,353 | BFY7DC4 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,563.52 | 634 | B292NQ7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,443.99 | 2,537 | B12W3P6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $18,436.70 | 662 | BS2F741 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,150.22 | 4,642 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,616.06 | 1,302 | BPRBTY7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,400.42 | 1,242 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,239.78 | 2,174 | B7F2TY6 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,361.75 | 7,145 | BN4JN37 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,239.96 | 2,741 | BMVBZF5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,206.01 | 1,303 | BM7V485 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $15,112.71 | 2,007 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,579.88 | 3,063 | 2107437 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $14,567.26 | 4,174 | BZ8FPH3 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $14,425.32 | 3,963 | BYTYP72 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,152.16 | 4,114 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,723.20 | 8,577 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,600.48 | 1,336 | BQV0J03 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,240.87 | 2,503 | BMF7DT9 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,991.30 | 2,770 | BDRJH21 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,957.30 | 4,799 | BKRRKY7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,952.03 | 4,303 | BZC0D70 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $12,652.20 | 6,390 | BRK0149 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $12,182.24 | 4,172 | BKX9NQ0 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,056.12 | 2,414 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,743.90 | 1,214 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,553.40 | 1,980 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,407.60 | 2,520 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $10,092.56 | 6,154 | BN13S71 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,999.99 | 3,861 | B5LL2C2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,939.85 | 8,355 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,789.00 | 3,995 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,608.00 | 1,600 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,579.22 | 1,326 | BP2NYN2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,742.12 | 3,173 | BPTK6Z2 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $7,664.44 | 3,532 | BDDVW37 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,451.10 | 2,435 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,247.72 | 9,267 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,706.77 | 2,289 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,860.57 | 8,252 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,999.70 | 2,941 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,869.13 | 931 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,420.58 | 2,663 | BLBR8D5 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,413.17 | 9,895 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,989.14 | 4,171 | BNNXX18 |
| -- | -- | FIRST TRACKS BIOTHERAPEUTICS INC COMMON STOCK USD | -- | $00.00 | 1,186 | -- |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 40.26% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 34,577,107 | -- | 5,639 | -- |
| 29.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,336,515 | -- | 4,132 | -- |
| 26.43% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,699,850 | -- | 3,702 | -- |
| 18.84% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 16,181,767 | -- | 2,639 | -- |
| 15.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,496,048 | -- | 2,201 | -- |
| 4.52% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,881,417 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $30,348,238.36 | 30,348,238 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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