BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $84,456,704
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/15/2026- NAV
- NAV Change
- Market Price $87.97
- Market Price Change $+0.33
- Trading Volume (M) 6,299
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $84,456,704
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/15/2026- NAV
- NAV Change
- Market Price $87.97
- Market Price Change $+0.33
- Trading Volume (M) 6,299
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/14/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.93% | GILD | GILEAD SCIENCES INC | -- | $4,148,471.65 | 29,537 | 2369174 |
| 4.73% | AMGN | AMGEN INC | -- | $3,978,018.25 | 11,335 | 2023607 |
| 4.67% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,933,655.12 | 8,854 | 2931034 |
| 3.99% | REGN | REGENERON PHARMACEUTICALS | -- | $3,354,464.40 | 4,440 | 2730190 |
| 2.29% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,923,775.88 | 5,668 | B00FWN1 |
| 1.68% | INSM | INSMED INC | -- | $1,413,734.40 | 9,216 | 2614487 |
| 1.48% | RVMD | REVOLUTION MEDICINES INC | -- | $1,245,468.72 | 8,472 | BL71K91 |
| 1.33% | BIIB | BIOGEN INC | -- | $1,122,616.08 | 6,273 | 2455965 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,083,605.42 | 1,873 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $1,003,960.20 | 1,212 | BDVLM39 |
| 1.06% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $894,187.12 | 18,316 | BMVP7Y0 |
| 1.06% | MRNA | MODERNA INC | -- | $892,150.56 | 16,884 | BGSXTS3 |
| 1.06% | ROIV | ROIVANT SCIENCES LTD | -- | $891,101.12 | 30,601 | BMW4NZ9 |
| 1.01% | ILMN | ILLUMINA INC | -- | $852,032.16 | 6,538 | 2613990 |
| 0.99% | INCY | INCYTE CORP | -- | $831,244.21 | 8,509 | 2471950 |
| 0.82% | SMMT | SUMMIT THERAPEUTICS INC | -- | $691,177.50 | 33,150 | BMTVQS7 |
| 0.81% | VTRS | VIATRIS INC | -- | $684,747.57 | 49,227 | BMWS3X9 |
| 0.78% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $657,329.04 | 2,631 | BV9G6B8 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $645,961.77 | 8,289 | BK1KWG8 |
| 0.75% | MEDP | MEDPACE HOLDINGS INC | -- | $630,240.00 | 1,212 | BDCBC61 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $561,436.52 | 4,292 | 2623911 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $542,155.88 | 7,063 | BDJ0LS6 |
| 0.63% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $528,988.86 | 2,631 | B4Q5ZN4 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $515,540.18 | 982 | BD59BS7 |
| 0.60% | EXEL | EXELIXIS INC | -- | $509,229.44 | 11,104 | 2576941 |
| 0.59% | SNY | SANOFI-ADR | -- | $498,457.32 | 10,463 | 2964557 |
| 0.58% | GH | GUARDANT HEALTH INC | -- | $484,358.40 | 5,606 | BFXC911 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $479,355.11 | 4,871 | BK6H543 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $456,129.81 | 8,223 | 2437071 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $423,770.00 | 1,367 | BYYWPW6 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $409,227.60 | 1,191 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $402,801.66 | 2,187 | BYZR4X4 |
| 0.47% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $399,406.41 | 5,989 | BYQBFJ8 |
| 0.46% | PCVX | VAXCYTE INC | -- | $386,162.28 | 6,153 | BKPVGH6 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $367,809.78 | 7,426 | BSLSJJ0 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $349,399.10 | 5,266 | BBBSBJ5 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $339,646.26 | 5,046 | 2975098 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $338,040.00 | 1,252 | BD6JX35 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $334,073.20 | 43,957 | BNSP0B8 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $330,225.00 | 2,625 | BLC89B2 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $328,712.60 | 3,130 | BMVBZD3 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $313,538.99 | 3,489 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $285,780.88 | 2,729 | BDCBCD8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $258,309.38 | 3,538 | B17VCN9 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $254,857.60 | 2,920 | BF2YWG4 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $253,240.60 | 6,940 | BLR6XK8 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $249,905.10 | 2,579 | BJDX8Y8 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $243,572.16 | 12,064 | BT18HP9 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $242,880.80 | 3,610 | BRBCSP4 |
| 0.29% | ALKS | ALKERMES PLC | -- | $241,323.75 | 7,125 | B3P6D26 |
| 0.28% | TERN | TERNS PHARMACEUTICALS INC | -- | $239,535.96 | 4,547 | BMDJ0C9 |
| 0.28% | ERAS | ERASCA INC | -- | $236,298.30 | 13,238 | BNLYBF3 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $233,353.44 | 4,104 | BDHF4K6 |
| 0.27% | IMVT | IMMUNOVANT INC | -- | $231,091.20 | 8,704 | BJRFSB7 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $223,286.10 | 5,466 | BYTQ6X1 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $216,186.65 | 4,363 | BFZQ0L8 |
| 0.26% | SYRE | SPYRE THERAPEUTICS INC | -- | $214,881.57 | 3,357 | BQBBDY8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $211,107.95 | 3,557 | BRJ3GY4 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $207,373.68 | 2,344 | BM9HHL5 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $202,463.26 | 5,114 | BLB0YQ9 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $197,953.68 | 852 | 2501578 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $177,960.75 | 4,477 | BDD19F8 |
| 0.21% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $177,329.04 | 3,332 | BQS9486 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $176,490.24 | 13,452 | BFNF1D6 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $176,224.65 | 5,345 | BTZRLN8 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $169,238.16 | 4,914 | BP8JSP4 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $166,160.72 | 3,944 | BLFGJD5 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $160,459.74 | 7,287 | 2713317 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $152,038.60 | 4,585 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $150,529.02 | 2,622 | BGKG6G7 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $139,422.78 | 7,038 | BN15WD1 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $138,747.14 | 2,069 | BKVF0J2 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $138,537.48 | 5,758 | BP2P6L0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $136,684.80 | 6,780 | BD2B4V0 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $135,342.36 | 3,051 | BL55460 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $134,260.39 | 1,819 | BMH5RL1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $132,926.82 | 5,298 | BKX9VD3 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $131,986.80 | 4,356 | BK6L288 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $124,744.00 | 5,030 | BKS3RS7 |
| 0.15% | ALMS | ALUMIS INC | -- | $123,743.34 | 5,406 | BPLQG36 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $122,819.61 | 2,451 | B72ZBG4 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $121,474.25 | 3,755 | BK0VHF6 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $117,632.70 | 2,610 | BFXC933 |
| 0.14% | VCYT | VERACYTE INC | -- | $116,585.70 | 3,399 | BFTWZY0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $115,023.36 | 1,632 | BMGJZJ8 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $113,874.15 | 2,539 | BMFD115 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $112,704.75 | 7,641 | BN2R582 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $106,819.67 | 10,183 | B9NSBM2 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $103,710.75 | 10,725 | 2100362 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $101,498.67 | 4,131 | BJ62Z18 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $99,254.15 | 4,481 | B8DPDT7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $95,636.46 | 6,582 | BJ5FZ74 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $94,788.82 | 4,417 | BLB0YH0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $93,465.66 | 4,262 | BV2DHY6 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $92,450.88 | 3,384 | BP9N0G0 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $92,125.53 | 3,771 | BN7Q7R7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $92,103.96 | 1,963 | BRXB0C0 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,341.88 | 5,684 | BFWLC09 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $87,534.26 | 2,441 | BJQ05Z6 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $86,362.98 | 3,201 | BPCQZY9 |
| 0.10% | GRAL | GRAIL INC | -- | $84,065.85 | 1,665 | BSLSSX7 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $83,383.20 | 2,504 | BCBVTX1 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $83,280.92 | 1,186 | BDRW1L7 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $82,703.00 | 1,910 | BQKXDX4 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,529.32 | 9,307 | BNZB1X8 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $80,486.14 | 2,282 | BMVNDH9 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $80,002.18 | 2,753 | BBC9WC7 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $79,473.24 | 4,697 | BPCK358 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,002.18 | 22,317 | BM9FJ13 |
| 0.09% | PHVS | PHARVARIS NV | -- | $78,583.20 | 2,740 | BMZ2X38 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $76,953.24 | 5,481 | BJH9ZN0 |
| 0.09% | INVA | INNOVIVA INC | -- | $76,585.54 | 3,166 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $76,324.08 | 2,172 | BSBMN89 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,001.82 | 958 | BCDWBX6 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $74,639.00 | 5,050 | BYZM6C2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $73,709.85 | 2,039 | BR3T9B6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,463.46 | 2,474 | BKSGZN7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,654.80 | 4,396 | BMVLGP2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $67,525.95 | 6,719 | BK4PZ38 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $67,433.52 | 3,608 | BMX9K07 |
| 0.08% | ARDX | ARDELYX INC | -- | $66,363.72 | 10,484 | BN89V40 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $64,107.68 | 17,612 | BF0DMK7 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $62,962.39 | 1,919 | BQXJKH2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $62,229.84 | 2,708 | BQB42F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $60,213.42 | 15,129 | BKM5C84 |
| 0.07% | HROW | HARROW INC | -- | $60,109.40 | 1,586 | BHNDW86 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $59,782.80 | 15,528 | BWJDYK1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $59,482.11 | 8,049 | BYZG9R0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,387.06 | 1,874 | BLCD809 |
| 0.07% | NVAX | NOVAVAX INC | -- | $58,427.96 | 6,964 | BJDQXG4 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $57,067.50 | 3,261 | BP7KZP7 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $56,937.76 | 2,057 | BSRK699 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $55,843.80 | 3,426 | BMZ4LN0 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,154.10 | 11,710 | BNC1BX1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $54,974.50 | 4,865 | BYSS4X4 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,863.00 | 3,532 | BYP80F1 |
| 0.06% | SVRA | SAVARA INC | -- | $52,815.07 | 8,701 | BYXGN81 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $51,996.62 | 881 | BL95N25 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,660.99 | 621 | BNSP8K3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,749.26 | 3,539 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $49,850.66 | 14,122 | BPNTJ34 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $49,722.20 | 2,330 | BQB42H3 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $48,812.24 | 1,766 | BMGTLY5 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $48,737.12 | 12,962 | BL53SR3 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,399.12 | 1,358 | BX7RSN3 |
| 0.06% | GERN | GERON CORP | -- | $48,308.61 | 27,293 | 2370381 |
| 0.05% | SEPN | SEPTERNA INC | -- | $46,160.69 | 1,913 | BQNKXX2 |
| 0.05% | QURE | UNIQURE NV | -- | $45,527.76 | 2,664 | BJFSR88 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $45,194.76 | 4,292 | BKVDFF7 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $44,474.04 | 2,652 | BP6C0S2 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $44,319.00 | 5,214 | B8K7T65 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $43,866.98 | 2,162 | BD06CS0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,066.65 | 7,095 | BLR7H87 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $42,672.56 | 3,368 | BJLKVS6 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $42,440.00 | 2,000 | BZ7PJQ1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,455.82 | 1,939 | BNFWZS4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,063.75 | 1,729 | B3X26D8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,654.48 | 2,602 | BMFX8Y7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,630.24 | 11,388 | BMFJJ97 |
| 0.05% | XNCR | XENCOR INC | -- | $39,243.87 | 3,137 | BGCYWN8 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $38,848.89 | 3,441 | BFYQFJ2 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $38,331.23 | 3,997 | BRXYZ57 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,248.10 | 2,526 | BM90J52 |
| 0.04% | MNKD | MANNKIND CORP | -- | $36,096.76 | 13,174 | BF081J4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,988.80 | 2,168 | BMNDK09 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,884.60 | 6,187 | BMVV9R5 |
| 0.04% | OMER | OMEROS CORP | -- | $35,875.20 | 3,030 | B4NB858 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $35,770.05 | 8,223 | BZ0QMB7 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,415.92 | 4,228 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,009.94 | 3,721 | BYZD465 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,883.22 | 7,243 | BYWVTY5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $32,682.57 | 2,237 | BQS7491 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,149.44 | 1,464 | BD9GVY0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,052.40 | 1,145 | BGL0JK3 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,949.90 | 1,270 | BKLCWZ3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,770.49 | 1,857 | BT9K6D8 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,765.76 | 2,434 | BMFK3H6 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,096.00 | 2,736 | BDZ30Q0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $29,886.32 | 4,474 | BJQ0608 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,556.60 | 7,718 | BPBJFM7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $28,200.99 | 1,777 | BRJJYT3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $28,110.32 | 6,958 | B3MZ6K5 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,430.59 | 3,333 | BQHN6C7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,586.40 | 3,368 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,403.00 | 2,300 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,390.03 | 777 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $24,079.80 | 804 | BPBPCG8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,885.40 | 2,310 | BRCFFK6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,554.74 | 2,406 | BLFBZ32 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $23,195.50 | 4,034 | BMC3HS7 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,981.14 | 1,638 | BP81RK8 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,857.12 | 2,442 | BSMLR16 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,601.67 | 4,641 | BMXNGZ6 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,491.30 | 2,847 | BJDX8Z9 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,908.52 | 9,609 | BFZNYB7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,642.25 | 5,215 | BYVQJ96 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,243.33 | 909 | BTNMG41 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,058.80 | 2,180 | BKLXFX5 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $20,951.00 | 10,220 | BBNBTD2 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $20,817.07 | 3,121 | BQ6C357 |
| 0.02% | KMDA | KAMADA LTD | -- | $20,772.14 | 2,467 | B2Q9833 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,526.24 | 6,258 | BMCWKZ2 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $20,271.84 | 12,912 | B4N8MH9 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,251.35 | 6,429 | BN94K69 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,207.60 | 5,155 | BYV2W40 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,134.50 | 2,165 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,366.20 | 3,339 | BLN9Z50 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,249.35 | 2,715 | BP81R42 |
| 0.02% | IVVD | INVIVYD INC | -- | $19,073.67 | 11,847 | BM8NHS1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,570.84 | 2,537 | B12W3P6 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,309.92 | 634 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,170.46 | 1,242 | B9L5200 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,611.37 | 5,353 | BFY7DC4 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,896.88 | 4,642 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,886.94 | 1,302 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,457.18 | 2,174 | B7F2TY6 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,942.60 | 3,126 | BP0TQC5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,049.65 | 1,303 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,828.81 | 2,741 | BMVBZF5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,504.35 | 7,145 | BN4JN37 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $14,149.86 | 4,174 | BZ8FPH3 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,028.54 | 3,063 | 2107437 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,743.12 | 662 | BS2F741 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,726.57 | 4,303 | BZC0D70 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,411.64 | 4,114 | BK5MWR1 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,226.40 | 1,336 | BQV0J03 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,693.96 | 8,577 | BFMLGR4 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,364.56 | 3,963 | BYTYP72 |
| 0.01% | EOLS | EVOLUS INC | -- | $12,298.80 | 2,770 | BDRJH21 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $12,282.84 | 2,007 | BL5B6Z1 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,189.46 | 4,799 | BKRRKY7 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,139.55 | 2,503 | BMF7DT9 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,514.72 | 4,172 | BKX9NQ0 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,502.00 | 6,390 | BRK0149 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,887.14 | 2,414 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,537.52 | 1,214 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,018.80 | 1,980 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,928.80 | 2,520 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,150.57 | 3,861 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $8,984.84 | 6,154 | BN13S71 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,471.91 | 3,173 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,469.40 | 3,995 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,320.00 | 1,600 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,346.04 | 1,326 | BP2NYN2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,024.88 | 8,355 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,935.67 | 2,289 | BP7L561 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $6,887.40 | 3,532 | BDDVW37 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,848.31 | 9,267 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,477.10 | 2,435 | BKTV702 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,702.96 | 8,252 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,970.29 | 2,941 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,527.10 | 2,663 | BLBR8D5 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,319.84 | 931 | BTXQTX3 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,270.68 | 9,895 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,492.38 | 4,171 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $28.78 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 37.29% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,390,968 | -- | 5,174 | -- |
| 29.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,069,092 | -- | 4,132 | -- |
| 26.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,460,256 | -- | 3,702 | -- |
| 19.02% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 16,010,971 | -- | 2,639 | -- |
| 17.30% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,560,944 | -- | 2,400 | -- |
| 4.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,840,449 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $29,223,058.96 | 29,223,059 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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