BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,261,693
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/16/2026- NAV
- NAV Change
- Market Price $86.72
- Market Price Change $-1.25
- Trading Volume (M) 5,651
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $83,261,693
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/16/2026- NAV
- NAV Change
- Market Price $86.72
- Market Price Change $-1.25
- Trading Volume (M) 5,651
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/16/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.92% | GILD | GILEAD SCIENCES INC | -- | $4,092,351.35 | 29,537 | 2369174 |
| 4.76% | AMGN | AMGEN INC | -- | $3,960,335.65 | 11,335 | 2023607 |
| 4.63% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,857,245.10 | 8,854 | 2931034 |
| 3.98% | REGN | REGENERON PHARMACEUTICALS | -- | $3,312,240.00 | 4,440 | 2730190 |
| 2.18% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,814,496.84 | 5,668 | B00FWN1 |
| 1.58% | INSM | INSMED INC | -- | $1,315,952.64 | 9,216 | 2614487 |
| 1.52% | RVMD | REVOLUTION MEDICINES INC | -- | $1,264,615.44 | 8,472 | BL71K91 |
| 1.33% | BIIB | BIOGEN INC | -- | $1,104,173.46 | 6,273 | 2455965 |
| 1.31% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,087,295.23 | 1,873 | 2430412 |
| 1.21% | ARGX | ARGENX SE - ADR | -- | $1,003,960.20 | 1,212 | BDVLM39 |
| 1.11% | MRNA | MODERNA INC | -- | $923,217.12 | 16,884 | BGSXTS3 |
| 1.07% | ROIV | ROIVANT SCIENCES LTD | -- | $893,243.19 | 30,601 | BMW4NZ9 |
| 1.07% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $887,959.68 | 18,316 | BMVP7Y0 |
| 1.04% | ILMN | ILLUMINA INC | -- | $867,723.36 | 6,538 | 2613990 |
| 0.97% | INCY | INCYTE CORP | -- | $811,077.88 | 8,509 | 2471950 |
| 0.97% | SMMT | SUMMIT THERAPEUTICS INC | -- | $809,523.00 | 33,150 | BMTVQS7 |
| 0.83% | VTRS | VIATRIS INC | -- | $689,670.27 | 49,227 | BMWS3X9 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $642,480.39 | 8,289 | BK1KWG8 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $639,201.45 | 2,631 | BV9G6B8 |
| 0.75% | MEDP | MEDPACE HOLDINGS INC | -- | $624,967.80 | 1,212 | BDCBC61 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $551,135.72 | 4,292 | 2623911 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $531,561.38 | 7,063 | BDJ0LS6 |
| 0.63% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $520,490.73 | 2,631 | B4Q5ZN4 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $515,314.32 | 982 | BD59BS7 |
| 0.60% | SNY | SANOFI-ADR | -- | $499,294.36 | 10,463 | 2964557 |
| 0.60% | BNTX | BIONTECH SE-ADR | -- | $497,426.52 | 4,871 | BK6H543 |
| 0.59% | EXEL | EXELIXIS INC | -- | $492,795.52 | 11,104 | 2576941 |
| 0.58% | GH | GUARDANT HEALTH INC | -- | $480,434.20 | 5,606 | BFXC911 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $444,864.30 | 8,223 | 2437071 |
| 0.53% | ONC | BEONE MEDICINES LTD-ADR | -- | $438,396.90 | 1,367 | BYYWPW6 |
| 0.49% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $407,132.22 | 5,989 | BYQBFJ8 |
| 0.49% | TEM | TEMPUS AI INC-CL A | -- | $404,122.92 | 7,426 | BSLSJJ0 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $402,823.53 | 2,187 | BYZR4X4 |
| 0.46% | PCVX | VAXCYTE INC | -- | $382,716.60 | 6,153 | BKPVGH6 |
| 0.46% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $381,584.49 | 1,191 | BQ721R4 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $344,501.72 | 5,266 | BBBSBJ5 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $336,265.44 | 5,046 | 2975098 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $330,603.12 | 1,252 | BD6JX35 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $325,081.80 | 3,130 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $321,483.75 | 2,625 | BLC89B2 |
| 0.38% | IBRX | IMMUNITYBIO INC | -- | $318,688.25 | 43,957 | BNSP0B8 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $300,542.46 | 3,489 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $283,079.17 | 2,729 | BDCBCD8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $257,281.20 | 2,920 | BF2YWG4 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $253,674.60 | 3,538 | B17VCN9 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $251,158.60 | 6,940 | BLR6XK8 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $247,222.94 | 2,579 | BJDX8Y8 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $246,105.60 | 12,064 | BT18HP9 |
| 0.29% | ERAS | ERASCA INC | -- | $241,328.74 | 13,238 | BNLYBF3 |
| 0.29% | ALKS | ALKERMES PLC | -- | $240,575.63 | 7,125 | B3P6D26 |
| 0.29% | TERN | TERNS PHARMACEUTICALS INC | -- | $239,581.43 | 4,547 | BMDJ0C9 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $239,487.40 | 3,610 | BRBCSP4 |
| 0.29% | IMVT | IMMUNOVANT INC | -- | $238,054.40 | 8,704 | BJRFSB7 |
| 0.28% | SYRE | SPYRE THERAPEUTICS INC | -- | $233,982.90 | 3,357 | BQBBDY8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $228,674.88 | 4,104 | BDHF4K6 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $223,395.42 | 5,466 | BYTQ6X1 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $218,150.00 | 4,363 | BFZQ0L8 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $212,249.20 | 2,344 | BM9HHL5 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $207,835.51 | 3,557 | BRJ3GY4 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $202,156.42 | 5,114 | BLB0YQ9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $190,200.48 | 852 | 2501578 |
| 0.21% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $178,262.00 | 3,332 | BQS9486 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $176,086.68 | 13,452 | BFNF1D6 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $174,692.54 | 4,477 | BDD19F8 |
| 0.20% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $168,420.95 | 5,345 | BTZRLN8 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $163,144.80 | 4,914 | BP8JSP4 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $155,945.76 | 3,944 | BLFGJD5 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $154,848.75 | 7,287 | 2713317 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $151,855.20 | 4,585 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $147,435.06 | 2,622 | BGKG6G7 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $144,180.32 | 5,758 | BP2P6L0 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $140,413.80 | 6,780 | BD2B4V0 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $140,126.58 | 7,038 | BN15WD1 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $138,767.83 | 2,069 | BKVF0J2 |
| 0.16% | ALMS | ALUMIS INC | -- | $135,150.00 | 5,406 | BPLQG36 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $132,117.48 | 4,356 | BK6L288 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $128,874.24 | 3,051 | BL55460 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $128,158.62 | 5,298 | BKX9VD3 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $126,957.20 | 5,030 | BKS3RS7 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $123,182.68 | 1,819 | BMH5RL1 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $123,096.51 | 7,641 | BN2R582 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $122,075.05 | 3,755 | BK0VHF6 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $120,638.22 | 2,451 | B72ZBG4 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $115,118.26 | 2,539 | BMFD115 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $113,342.40 | 1,632 | BMGJZJ8 |
| 0.13% | VCYT | VERACYTE INC | -- | $112,268.97 | 3,399 | BFTWZY0 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $109,365.42 | 10,183 | B9NSBM2 |
| 0.13% | KOD | KODIAK SCIENCES INC | -- | $105,470.10 | 2,610 | BFXC933 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $103,415.04 | 3,384 | BP9N0G0 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $102,102.00 | 10,725 | 2100362 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $101,292.12 | 4,131 | BJ62Z18 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $95,724.52 | 4,262 | BV2DHY6 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $94,862.77 | 4,481 | B8DPDT7 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $94,744.65 | 4,417 | BLB0YH0 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $92,674.56 | 6,582 | BJ5FZ74 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,977.72 | 5,684 | BFWLC09 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $89,787.51 | 3,771 | BN7Q7R7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $88,963.16 | 1,963 | BRXB0C0 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $87,439.68 | 2,504 | BCBVTX1 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $87,067.20 | 3,201 | BPCQZY9 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $86,408.40 | 1,910 | BQKXDX4 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $86,264.94 | 2,441 | BJQ05Z6 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $83,277.81 | 4,697 | BPCK358 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,460.02 | 9,307 | BNZB1X8 |
| 0.10% | GRAL | GRAIL INC | -- | $82,367.55 | 1,665 | BSLSSX7 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $80,622.06 | 2,039 | BR3T9B6 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $80,341.20 | 22,317 | BM9FJ13 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $80,143.84 | 2,282 | BMVNDH9 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $79,693.74 | 5,481 | BJH9ZN0 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $79,343.40 | 1,186 | BDRW1L7 |
| 0.09% | PHVS | PHARVARIS NV | -- | $78,857.20 | 2,740 | BMZ2X38 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $77,909.90 | 2,753 | BBC9WC7 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $76,056.64 | 3,608 | BMX9K07 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,791.06 | 958 | BCDWBX6 |
| 0.09% | INVA | INNOVIVA INC | -- | $74,717.60 | 3,166 | BDDXF67 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $73,369.24 | 4,396 | BMVLGP2 |
| 0.09% | VCEL | VERICEL CORP | -- | $73,348.44 | 2,172 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,785.08 | 2,474 | BKSGZN7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $71,508.00 | 5,050 | BYZM6C2 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $69,674.50 | 11,710 | BNC1BX1 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $69,407.27 | 6,719 | BK4PZ38 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,925.60 | 17,612 | BF0DMK7 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,839.52 | 10,484 | BN89V40 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $64,802.44 | 2,708 | BQB42F1 |
| 0.08% | HROW | HARROW INC | -- | $64,470.90 | 1,586 | BHNDW86 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $63,749.18 | 1,919 | BQXJKH2 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $63,509.52 | 15,528 | BWJDYK1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $61,396.30 | 4,865 | BYSS4X4 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $60,980.70 | 3,261 | BP7KZP7 |
| 0.07% | NVAX | NOVAVAX INC | -- | $60,168.96 | 6,964 | BJDQXG4 |
| 0.07% | PGEN | PRECIGEN INC | -- | $59,759.55 | 15,129 | BKM5C84 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $58,918.68 | 8,049 | BYZG9R0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $58,806.12 | 1,874 | BLCD809 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,460.48 | 3,426 | BMZ4LN0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $55,271.59 | 2,057 | BSRK699 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,121.28 | 3,532 | BYP80F1 |
| 0.06% | EYPT | EYEPOINT INC | -- | $52,412.59 | 3,539 | BMGS7L1 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,291.26 | 1,766 | BMGTLY5 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,611.31 | 621 | BNSP8K3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $51,121.64 | 14,122 | BPNTJ34 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $50,700.80 | 2,330 | BQB42H3 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $49,644.46 | 12,962 | BL53SR3 |
| 0.06% | SVRA | SAVARA INC | -- | $49,073.64 | 8,701 | BYXGN81 |
| 0.06% | SEPN | SEPTERNA INC | -- | $47,805.87 | 1,913 | BQNKXX2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $47,468.28 | 881 | BL95N25 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $47,046.48 | 2,652 | BP6C0S2 |
| 0.06% | GERN | GERON CORP | -- | $46,125.17 | 27,293 | 2370381 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,868.32 | 1,358 | BX7RSN3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $44,840.40 | 5,214 | B8K7T65 |
| 0.05% | QURE | UNIQURE NV | -- | $44,781.84 | 2,664 | BJFSR88 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $43,907.16 | 4,292 | BKVDFF7 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,421.40 | 7,095 | BLR7H87 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $42,780.00 | 2,000 | BZ7PJQ1 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $42,470.48 | 3,368 | BJLKVS6 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $42,289.59 | 1,939 | BNFWZS4 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $42,288.72 | 2,162 | BD06CS0 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,253.94 | 1,729 | B3X26D8 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,329.73 | 3,997 | BRXYZ57 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,524.38 | 2,602 | BMFX8Y7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,516.36 | 11,388 | BMFJJ97 |
| 0.05% | ANNX | ANNEXON INC | -- | $39,163.71 | 6,187 | BMVV9R5 |
| 0.05% | XNCR | XENCOR INC | -- | $39,055.65 | 3,137 | BGCYWN8 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,483.64 | 8,223 | BZ0QMB7 |
| 0.05% | OMER | OMEROS CORP | -- | $37,996.20 | 3,030 | B4NB858 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,233.24 | 2,526 | BM90J52 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $36,379.04 | 2,168 | BMNDK09 |
| 0.04% | MNKD | MANNKIND CORP | -- | $36,228.50 | 13,174 | BF081J4 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $35,993.33 | 2,237 | BQS7491 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $35,418.27 | 7,243 | BYWVTY5 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,585.04 | 4,228 | BMCR7V2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $34,404.00 | 1,464 | BD9GVY0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,265.74 | 3,721 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $32,620.68 | 3,441 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,550.43 | 1,857 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $31,191.20 | 1,270 | BKLCWZ3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,449.34 | 2,434 | BMFK3H6 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,128.14 | 6,958 | B3MZ6K5 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,096.00 | 2,736 | BDZ30Q0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $29,796.84 | 4,474 | BJQ0608 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,325.06 | 7,718 | BPBJFM7 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $27,972.35 | 1,145 | BGL0JK3 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,963.87 | 3,333 | BQHN6C7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $26,866.44 | 4,034 | BMC3HS7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,601.69 | 1,777 | BRJJYT3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,022.40 | 2,406 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,685.29 | 777 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,196.00 | 2,300 | B91XRN2 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,013.84 | 3,368 | BJ0LT31 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $23,862.72 | 804 | BPBPCG8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,331.00 | 2,310 | BRCFFK6 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,272.26 | 2,442 | BSMLR16 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $22,773.33 | 9,609 | BFZNYB7 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,747.53 | 2,847 | BJDX8Z9 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,215.90 | 5,215 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,211.28 | 1,638 | BP81RK8 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,930.80 | 2,180 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $21,905.52 | 4,641 | BMXNGZ6 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,543.30 | 909 | BTNMG41 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,339.78 | 6,258 | BMCWKZ2 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $21,046.56 | 12,912 | B4N8MH9 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $20,951.00 | 10,220 | BBNBTD2 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,765.67 | 6,429 | BN94K69 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $20,536.18 | 3,121 | BQ6C357 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,516.90 | 5,155 | BYV2W40 |
| 0.02% | KMDA | KAMADA LTD | -- | $20,328.08 | 2,467 | B2Q9833 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,258.37 | 11,847 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,896.35 | 2,165 | BZ0G875 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,167.90 | 2,715 | BP81R42 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,032.30 | 3,339 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,789.03 | 5,353 | BFY7DC4 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,297.24 | 634 | B292NQ7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,164.92 | 2,537 | B12W3P6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,103.80 | 4,642 | BDFKQ07 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,462.52 | 1,242 | B9L5200 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,316.60 | 1,302 | BPRBTY7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,967.06 | 662 | BS2F741 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,130.16 | 3,126 | BP0TQC5 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,739.76 | 2,174 | B7F2TY6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,271.16 | 1,303 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,267.37 | 2,741 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $15,253.20 | 2,007 | BL5B6Z1 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,481.28 | 4,114 | BK5MWR1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,290.00 | 7,145 | BN4JN37 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,212.32 | 3,063 | 2107437 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $13,982.90 | 4,174 | BZ8FPH3 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,808.97 | 8,577 | BFMLGR4 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $13,474.20 | 3,963 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,210.21 | 4,303 | BZC0D70 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,879.04 | 1,336 | BQV0J03 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,813.33 | 4,799 | BKRRKY7 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,548.10 | 2,770 | BDRJH21 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,164.58 | 2,503 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $12,141.00 | 6,390 | BRK0149 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $12,098.80 | 4,172 | BKX9NQ0 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,790.58 | 2,414 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,731.76 | 1,214 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,177.20 | 1,980 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,979.20 | 2,520 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,806.94 | 3,861 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $9,600.24 | 6,154 | BN13S71 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,689.20 | 8,355 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,589.25 | 3,995 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,320.00 | 1,600 | 2517058 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,218.07 | 3,173 | BPTK6Z2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,207.94 | 1,326 | BP2NYN2 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $7,735.08 | 3,532 | BDDVW37 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,110.20 | 2,435 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,923.38 | 9,267 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,134.52 | 2,289 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,641.07 | 8,252 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,911.47 | 2,941 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,645.69 | 931 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,527.10 | 2,663 | BLBR8D5 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,328.07 | 9,895 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,833.15 | 4,171 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $29.35 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 37.47% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,201,415 | -- | 5,170 | -- |
| 29.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,936,992 | -- | 4,132 | -- |
| 26.83% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,341,903 | -- | 3,702 | -- |
| 19.13% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,926,603 | -- | 2,639 | -- |
| 15.95% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,283,233 | -- | 2,201 | -- |
| 4.59% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,820,212 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,600,725.72 | 28,600,726 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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