BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,722,598
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/24/2026- NAV
- NAV Change
- Market Price $82.71
- Market Price Change $-1.88
- Trading Volume (M) 22,923
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $77,722,598
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/24/2026- NAV
- NAV Change
- Market Price $82.71
- Market Price Change $-1.88
- Trading Volume (M) 22,923
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/24/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.84% | AMGN | AMGEN INC | -- | $3,718,039.05 | 10,791 | 2023607 |
| 4.77% | GILD | GILEAD SCIENCES INC | -- | $3,666,978.40 | 28,121 | 2369174 |
| 4.72% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,626,914.41 | 8,429 | 2931034 |
| 4.13% | REGN | REGENERON PHARMACEUTICALS | -- | $3,176,886.39 | 4,227 | 2730190 |
| 2.14% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,648,693.84 | 5,396 | B00FWN1 |
| 1.54% | INSM | INSMED INC | -- | $1,185,846.41 | 8,773 | 2614487 |
| 1.43% | BIIB | BIOGEN INC | -- | $1,100,932.98 | 5,971 | 2455965 |
| 1.42% | RVMD | REVOLUTION MEDICINES INC | -- | $1,091,194.50 | 8,065 | BL71K91 |
| 1.32% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,011,246.28 | 1,783 | 2430412 |
| 1.17% | ARGX | ARGENX SE - ADR | -- | $901,188.75 | 1,155 | BDVLM39 |
| 1.12% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $860,989.68 | 17,436 | BMVP7Y0 |
| 1.06% | MRNA | MODERNA INC | -- | $815,383.29 | 16,073 | BGSXTS3 |
| 1.04% | ROIV | ROIVANT SCIENCES LTD | -- | $798,562.94 | 29,134 | BMW4NZ9 |
| 1.04% | ILMN | ILLUMINA INC | -- | $795,925.12 | 6,224 | 2613990 |
| 1.00% | INCY | INCYTE CORP | -- | $766,854.30 | 8,102 | 2471950 |
| 0.91% | SMMT | SUMMIT THERAPEUTICS INC | -- | $696,844.80 | 31,560 | BMTVQS7 |
| 0.89% | VTRS | VIATRIS INC | -- | $683,760.35 | 46,865 | BMWS3X9 |
| 0.75% | BBIO | BRIDGEBIO PHARMA INC | -- | $578,252.48 | 7,891 | BK1KWG8 |
| 0.75% | -- | ASCENDIS PHARMA A/S | -- | $574,321.35 | 2,505 | -- |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $521,700.48 | 4,086 | 2623911 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $492,740.75 | 6,725 | BDJ0LS6 |
| 0.64% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $492,282.60 | 2,505 | B4Q5ZN4 |
| 0.64% | BNTX | BIONTECH SE-ADR | -- | $489,018.02 | 4,637 | BK6H543 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $478,572.26 | 934 | BD59BS7 |
| 0.62% | EXEL | EXELIXIS INC | -- | $475,060.74 | 10,571 | 2576941 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $474,512.67 | 5,337 | BFXC911 |
| 0.62% | MEDP | MEDPACE HOLDINGS INC | -- | $474,173.70 | 1,155 | BDCBC61 |
| 0.61% | SNY | SANOFI-ADR | -- | $465,928.80 | 9,960 | 2964557 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $421,434.82 | 5,702 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $416,293.04 | 7,828 | 2437071 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $391,340.80 | 1,301 | BYYWPW6 |
| 0.51% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $391,025.88 | 1,134 | BQ721R4 |
| 0.50% | AXSM | AXSOME THERAPEUTICS INC | -- | $387,168.72 | 2,082 | BYZR4X4 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $368,488.40 | 7,070 | BSLSJJ0 |
| 0.45% | PCVX | VAXCYTE INC | -- | $348,432.93 | 5,857 | BKPVGH6 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $327,514.48 | 5,014 | BBBSBJ5 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $324,843.84 | 1,192 | BD6JX35 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $313,989.44 | 4,804 | 2975098 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $311,410.00 | 2,980 | BMVBZD3 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $311,356.56 | 41,849 | BNSP0B8 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $286,285.44 | 2,499 | BLC89B2 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $281,986.11 | 3,321 | BMPRZV5 |
| 0.35% | ERAS | ERASCA INC | -- | $270,838.47 | 12,603 | BNLYBF3 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $259,800.00 | 2,598 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $243,240.48 | 6,608 | BLR6XK8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $238,246.00 | 2,780 | BF2YWG4 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $236,842.46 | 8,287 | BJRFSB7 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $236,053.16 | 3,437 | BRBCSP4 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $232,017.20 | 11,486 | BT18HP9 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $229,798.64 | 3,368 | B17VCN9 |
| 0.30% | TERN | TERNS PHARMACEUTICALS INC | -- | $228,960.81 | 4,329 | BMDJ0C9 |
| 0.29% | ALKS | ALKERMES PLC | -- | $225,975.04 | 6,784 | B3P6D26 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $224,699.44 | 2,456 | BJDX8Y8 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $222,665.32 | 3,196 | BQBBDY8 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,010.82 | 5,203 | BYTQ6X1 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $193,077.92 | 4,154 | BFZQ0L8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,179.43 | 4,869 | BLB0YQ9 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $190,995.91 | 2,231 | BM9HHL5 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $190,603.00 | 3,907 | BDHF4K6 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $187,328.70 | 810 | 2501578 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $187,042.64 | 3,386 | BRJ3GY4 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $169,074.24 | 5,088 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $163,362.46 | 4,262 | BDD19F8 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $160,331.12 | 12,806 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $152,336.52 | 6,937 | 2713317 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $152,106.24 | 2,496 | BGKG6G7 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $152,077.50 | 3,755 | BLFGJD5 |
| 0.19% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $144,339.77 | 3,173 | BQS9486 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $141,271.14 | 5,482 | BP2P6L0 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $139,030.16 | 4,678 | BP8JSP4 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $137,878.28 | 4,366 | BKY5JZ8 |
| 0.18% | ORKA | ORUKA THERAPEUTICS INC | -- | $135,989.10 | 1,970 | BKVF0J2 |
| 0.17% | ALMS | ALUMIS INC | -- | $128,289.78 | 5,146 | BPLQG36 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $128,240.98 | 6,454 | BD2B4V0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $122,342.00 | 6,700 | BN15WD1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,323.44 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $116,139.84 | 2,334 | B72ZBG4 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $112,425.17 | 4,147 | BK6L288 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $111,382.56 | 2,484 | BFXC933 |
| 0.14% | VCYT | VERACYTE INC | -- | $111,126.21 | 3,237 | BFTWZY0 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $110,070.75 | 7,275 | BN2R582 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $109,859.75 | 3,575 | BK0VHF6 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $109,451.76 | 2,904 | BL55460 |
| 0.14% | ADMA | ADMA BIOLOGICS INC | -- | $109,165.70 | 9,695 | B9NSBM2 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $106,992.90 | 1,554 | BMGJZJ8 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $106,952.25 | 2,417 | BMFD115 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $106,431.40 | 1,732 | BMH5RL1 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $105,719.04 | 4,788 | BKS3RS7 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $94,785.30 | 3,933 | BJ62Z18 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $91,277.40 | 10,210 | 2100362 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $91,223.84 | 4,058 | BV2DHY6 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $88,637.22 | 3,222 | BP9N0G0 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $88,615.38 | 6,267 | BJ5FZ74 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $86,599.80 | 4,266 | B8DPDT7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $86,483.76 | 5,412 | BFWLC09 |
| 0.11% | GRAL | GRAIL INC | -- | $86,201.28 | 1,584 | BSLSSX7 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $85,648.80 | 3,048 | BPCQZY9 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $84,090.89 | 8,861 | BNZB1X8 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $82,096.50 | 3,435 | BMX9K07 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $81,645.48 | 2,172 | BMVNDH9 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $80,017.30 | 1,870 | BRXB0C0 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $79,085.72 | 2,324 | BJQ05Z6 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $76,811.49 | 3,591 | BN7Q7R7 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $76,274.46 | 591 | BNSP8K3 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $76,202.88 | 4,472 | BPCK358 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $75,191.38 | 5,218 | BJH9ZN0 |
| 0.10% | PHVS | PHARVARIS NV | -- | $74,667.04 | 2,608 | BMZ2X38 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $74,573.46 | 21,246 | BM9FJ13 |
| 0.10% | VCEL | VERICEL CORP | -- | $73,667.88 | 2,067 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,534.00 | 2,355 | BKSGZN7 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $71,798.32 | 913 | BCDWBX6 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $71,347.20 | 11,148 | BNC1BX1 |
| 0.09% | INVA | INNOVIVA INC | -- | $71,039.98 | 3,014 | BDDXF67 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $70,962.96 | 1,941 | BR3T9B6 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $70,426.27 | 2,621 | BBC9WC7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,822.48 | 4,186 | BMVLGP2 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $69,283.98 | 1,818 | BQKXDX4 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $68,445.29 | 14,783 | BWJDYK1 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $66,475.52 | 1,129 | BDRW1L7 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $66,326.52 | 6,396 | BK4PZ38 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,533.04 | 4,808 | BYZM6C2 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $61,447.95 | 3,105 | BP7KZP7 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $60,362.88 | 2,384 | BCBVTX1 |
| 0.08% | HROW | HARROW INC | -- | $59,986.70 | 1,511 | BHNDW86 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,488.52 | 14,404 | BKM5C84 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,386.95 | 9,981 | BN89V40 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $58,414.35 | 2,579 | BQB42F1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $58,358.96 | 1,826 | BQXJKH2 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $57,761.04 | 4,632 | BYSS4X4 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,681.92 | 16,768 | BF0DMK7 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,020.34 | 7,663 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $54,490.38 | 6,629 | BJDQXG4 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $54,060.96 | 3,362 | BYP80F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $52,271.20 | 1,784 | BLCD809 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,211.00 | 12,340 | BL53SR3 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $51,166.44 | 1,682 | BMGTLY5 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $51,151.50 | 2,526 | BP6C0S2 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $50,643.33 | 3,261 | BMZ4LN0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,535.98 | 1,958 | BSRK699 |
| 0.06% | EYPT | EYEPOINT INC | -- | $46,391.13 | 3,369 | BMGS7L1 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $46,279.24 | 839 | BL95N25 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $45,905.44 | 1,904 | BZ7PJQ1 |
| 0.06% | QURE | UNIQURE NV | -- | $45,724.08 | 2,536 | BJFSR88 |
| 0.06% | ALVO | ALVOTECH SA | -- | $45,444.10 | 13,445 | BPNTJ34 |
| 0.06% | SEPN | SEPTERNA INC | -- | $44,924.07 | 1,821 | BQNKXX2 |
| 0.06% | SVRA | SAVARA INC | -- | $42,419.20 | 8,285 | BYXGN81 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $41,990.00 | 1,292 | BX7RSN3 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $41,840.64 | 4,086 | BKVDFF7 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,861.70 | 6,754 | BLR7H87 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $40,398.54 | 2,058 | BD06CS0 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $40,363.61 | 2,219 | BQB42H3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,318.95 | 1,645 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,101.04 | 4,963 | B8K7T65 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,522.86 | 1,846 | BNFWZS4 |
| 0.05% | OMER | OMEROS CORP | -- | $39,020.52 | 2,884 | B4NB858 |
| 0.05% | GERN | GERON CORP | -- | $38,977.50 | 25,985 | 2370381 |
| 0.05% | XNCR | XENCOR INC | -- | $38,771.26 | 2,987 | BGCYWN8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,510.20 | 3,206 | BJLKVS6 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $37,289.00 | 3,805 | BRXYZ57 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $37,179.77 | 2,477 | BMFX8Y7 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $36,787.20 | 3,840 | BMC3HS7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $35,673.47 | 10,843 | BMFJJ97 |
| 0.05% | ANNX | ANNEXON INC | -- | $34,639.08 | 5,891 | BMVV9R5 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $33,973.44 | 2,064 | BMNDK09 |
| 0.04% | MNKD | MANNKIND CORP | -- | $33,863.40 | 12,542 | BF081J4 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,367.25 | 4,025 | BMCR7V2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,020.79 | 2,129 | BQS7491 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,877.60 | 7,828 | BZ0QMB7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,798.92 | 3,542 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,807.32 | 2,406 | BM90J52 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,764.15 | 1,395 | BD9GVY0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $30,342.40 | 6,896 | BYWVTY5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,237.48 | 3,276 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,127.35 | 1,767 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,596.60 | 1,210 | BKLCWZ3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $29,032.01 | 2,317 | BMFK3H6 |
| 0.04% | ARVN | ARVINAS INC | -- | $27,185.76 | 2,604 | BDZ30Q0 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $27,183.90 | 7,347 | BPBJFM7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,028.39 | 6,623 | B3MZ6K5 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,979.90 | 4,259 | BJQ0608 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,138.08 | 3,174 | BQHN6C7 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $25,114.82 | 1,091 | BGL0JK3 |
| 0.03% | ABSI | ABSCI CORP | -- | $24,116.74 | 6,121 | BN94K69 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,788.52 | 3,206 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,531.75 | 2,189 | B91XRN2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,380.33 | 1,693 | BRJJYT3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,083.20 | 2,290 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,444.89 | 741 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,833.10 | 765 | BPBPCG8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $21,246.40 | 2,710 | BJDX8Z9 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,150.90 | 5,958 | BMCWKZ2 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,131.88 | 9,148 | BFZNYB7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,100.10 | 4,907 | BYV2W40 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,064.50 | 2,325 | BSMLR16 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $20,502.64 | 1,129 | BS2CR64 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,450.70 | 2,199 | BRCFFK6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,253.12 | 4,964 | BYVQJ96 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $20,062.26 | 4,419 | BMXNGZ6 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,702.80 | 1,560 | BP81RK8 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,505.00 | 2,075 | BKLXFX5 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,441.44 | 2,348 | B2Q9833 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,384.65 | 865 | BTNMG41 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $19,344.00 | 2,976 | BP0TQC5 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,175.52 | 12,292 | B4N8MH9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,785.68 | 2,584 | BP81R42 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,582.39 | 9,729 | BBNBTD2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,054.36 | 2,061 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,383.66 | 3,178 | BLN9Z50 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,380.35 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,274.40 | 604 | B292NQ7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,001.87 | 629 | BS2F741 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,653.13 | 2,417 | B12W3P6 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,465.88 | 11,278 | BM8NHS1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,758.36 | 2,609 | BMVBZF5 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,732.42 | 1,182 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,600.26 | 2,069 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,558.40 | 4,420 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,375.99 | 1,239 | BPRBTY7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,306.75 | 6,803 | BN4JN37 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,714.70 | 1,911 | BL5B6Z1 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,523.60 | 5,096 | BFY7DC4 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,272.40 | 1,240 | BM7V485 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,981.40 | 2,638 | BDRJH21 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,326.12 | 2,916 | 2107437 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,653.73 | 2,383 | BMF7DT9 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,605.16 | 3,774 | BYTYP72 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,940.74 | 1,273 | BQV0J03 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,759.04 | 8,166 | BFMLGR4 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,635.48 | 4,097 | BZC0D70 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,564.34 | 3,974 | BZ8FPH3 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,552.20 | 3,916 | BK5MWR1 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,439.36 | 3,972 | BKX9NQ0 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,194.05 | 4,569 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,647.00 | 6,084 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,938.63 | 1,157 | BKC9SX3 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,631.12 | 3,676 | B5LL2C2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,490.74 | 2,298 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,118.56 | 1,884 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,096.00 | 2,400 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $8,552.68 | 5,858 | BN13S71 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $8,136.04 | 3,362 | BDDVW37 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,100.39 | 3,803 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,645.46 | 1,523 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,401.18 | 1,263 | BP2NYN2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,204.73 | 7,954 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,929.22 | 2,179 | BP7L561 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,884.46 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,613.80 | 3,020 | BPTK6Z2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,930.82 | 8,823 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,499.90 | 7,857 | BMYTJP4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,816.50 | 2,535 | BLBR8D5 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,775.54 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,312.00 | 2,800 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,728.37 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,416.27 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 36.47% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 28,045,130 | -- | 4,754 | -- |
| 28.40% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,839,098 | -- | 3,702 | -- |
| 27.04% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,789,027 | -- | 3,524 | -- |
| 20.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,568,174 | -- | 2,639 | -- |
| 16.89% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,984,293 | -- | 2,201 | -- |
| 4.86% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,734,238 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,113,548.24 | 26,113,548 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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