BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $84,456,704
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/15/2026- NAV
- NAV Change
- Market Price $87.97
- Market Price Change $+0.33
- Trading Volume (M) 6,308
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $84,456,704
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/15/2026- NAV
- NAV Change
- Market Price $87.97
- Market Price Change $+0.33
- Trading Volume (M) 6,308
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/15/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.89% | GILD | GILEAD SCIENCES INC | -- | $4,128,386.49 | 29,537 | 2369174 |
| 4.67% | AMGN | AMGEN INC | -- | $3,947,073.70 | 11,335 | 2023607 |
| 4.63% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,910,811.80 | 8,854 | 2931034 |
| 3.96% | REGN | REGENERON PHARMACEUTICALS | -- | $3,347,449.20 | 4,440 | 2730190 |
| 2.24% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,889,654.52 | 5,668 | B00FWN1 |
| 1.60% | INSM | INSMED INC | -- | $1,352,355.84 | 9,216 | 2614487 |
| 1.53% | RVMD | REVOLUTION MEDICINES INC | -- | $1,292,318.88 | 8,472 | BL71K91 |
| 1.34% | BIIB | BIOGEN INC | -- | $1,132,527.42 | 6,273 | 2455965 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,081,807.34 | 1,873 | 2430412 |
| 1.21% | ARGX | ARGENX SE - ADR | -- | $1,019,134.44 | 1,212 | BDVLM39 |
| 1.08% | MRNA | MODERNA INC | -- | $916,125.84 | 16,884 | BGSXTS3 |
| 1.06% | ROIV | ROIVANT SCIENCES LTD | -- | $899,363.39 | 30,601 | BMW4NZ9 |
| 1.06% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $891,989.20 | 18,316 | BMVP7Y0 |
| 1.02% | ILMN | ILLUMINA INC | -- | $864,715.88 | 6,538 | 2613990 |
| 0.98% | INCY | INCYTE CORP | -- | $826,223.90 | 8,509 | 2471950 |
| 0.83% | SMMT | SUMMIT THERAPEUTICS INC | -- | $700,128.00 | 33,150 | BMTVQS7 |
| 0.81% | VTRS | VIATRIS INC | -- | $682,286.22 | 49,227 | BMWS3X9 |
| 0.76% | BBIO | BRIDGEBIO PHARMA INC | -- | $644,055.30 | 8,289 | BK1KWG8 |
| 0.75% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $635,939.01 | 2,631 | BV9G6B8 |
| 0.74% | MEDP | MEDPACE HOLDINGS INC | -- | $628,470.48 | 1,212 | BDCBC61 |
| 0.67% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $564,140.48 | 4,292 | 2623911 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $542,579.66 | 7,063 | BDJ0LS6 |
| 0.62% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $524,437.23 | 2,631 | B4Q5ZN4 |
| 0.60% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $509,245.56 | 982 | BD59BS7 |
| 0.59% | SNY | SANOFI-ADR | -- | $502,433.26 | 10,463 | 2964557 |
| 0.58% | EXEL | EXELIXIS INC | -- | $491,685.12 | 11,104 | 2576941 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $484,518.37 | 4,871 | BK6H543 |
| 0.56% | GH | GUARDANT HEALTH INC | -- | $475,725.16 | 5,606 | BFXC911 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $454,485.21 | 8,223 | 2437071 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $437,357.98 | 1,367 | BYYWPW6 |
| 0.50% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $424,919.55 | 5,989 | BYQBFJ8 |
| 0.50% | TEM | TEMPUS AI INC-CL A | -- | $418,900.66 | 7,426 | BSLSJJ0 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $404,856.63 | 1,191 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $402,801.66 | 2,187 | BYZR4X4 |
| 0.44% | PCVX | VAXCYTE INC | -- | $371,948.85 | 6,153 | BKPVGH6 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $344,238.42 | 5,266 | BBBSBJ5 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $343,380.30 | 5,046 | 2975098 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $341,985.46 | 43,957 | BNSP0B8 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $336,212.08 | 1,252 | BD6JX35 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $327,867.50 | 3,130 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $318,885.00 | 2,625 | BLC89B2 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $310,521.00 | 3,489 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $287,745.76 | 2,729 | BDCBCD8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $260,290.66 | 3,538 | B17VCN9 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $256,405.20 | 2,920 | BF2YWG4 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $252,740.80 | 12,064 | BT18HP9 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $252,060.80 | 6,940 | BLR6XK8 |
| 0.29% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $248,615.60 | 2,579 | BJDX8Y8 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $244,324.80 | 3,610 | BRBCSP4 |
| 0.29% | ERAS | ERASCA INC | -- | $240,931.60 | 13,238 | BNLYBF3 |
| 0.28% | TERN | TERNS PHARMACEUTICALS INC | -- | $239,672.37 | 4,547 | BMDJ0C9 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $238,750.72 | 8,704 | BJRFSB7 |
| 0.28% | ALKS | ALKERMES PLC | -- | $236,692.50 | 7,125 | B3P6D26 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $232,943.04 | 4,104 | BDHF4K6 |
| 0.27% | SYRE | SPYRE THERAPEUTICS INC | -- | $231,599.43 | 3,357 | BQBBDY8 |
| 0.26% | APLS | APELLIS PHARMACEUTICALS INC | -- | $223,258.77 | 5,466 | BYTQ6X1 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $215,183.16 | 4,363 | BFZQ0L8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $209,436.16 | 3,557 | BRJ3GY4 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $209,366.08 | 2,344 | BM9HHL5 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $202,565.54 | 5,114 | BLB0YQ9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $191,776.68 | 852 | 2501578 |
| 0.21% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $180,761.00 | 3,332 | BQS9486 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $178,050.29 | 4,477 | BDD19F8 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $175,548.60 | 13,452 | BFNF1D6 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,819.40 | 5,345 | BTZRLN8 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $167,125.14 | 4,914 | BP8JSP4 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $161,506.80 | 3,944 | BLFGJD5 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $158,565.12 | 7,287 | 2713317 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $154,514.50 | 4,585 | BKY5JZ8 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $151,079.64 | 2,622 | BGKG6G7 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $146,990.40 | 6,780 | BD2B4V0 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $145,850.14 | 5,758 | BP2P6L0 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $140,619.24 | 7,038 | BN15WD1 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $135,622.95 | 2,069 | BKVF0J2 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $133,642.08 | 4,356 | BK6L288 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $132,565.95 | 3,051 | BL55460 |
| 0.15% | ALMS | ALUMIS INC | -- | $130,608.96 | 5,406 | BPLQG36 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $130,604.20 | 1,819 | BMH5RL1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $130,224.84 | 5,298 | BKX9VD3 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $127,510.50 | 5,030 | BKS3RS7 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $122,402.94 | 2,451 | B72ZBG4 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $120,835.90 | 3,755 | BK0VHF6 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $118,359.09 | 7,641 | BN2R582 |
| 0.14% | VCYT | VERACYTE INC | -- | $115,701.96 | 3,399 | BFTWZY0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $114,533.76 | 1,632 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $111,589.05 | 2,539 | BMFD115 |
| 0.13% | KOD | KODIAK SCIENCES INC | -- | $109,567.80 | 2,610 | BFXC933 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $108,448.95 | 10,183 | B9NSBM2 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $104,018.58 | 4,131 | BJ62Z18 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $102,941.28 | 3,384 | BP9N0G0 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $101,244.00 | 10,725 | 2100362 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $97,372.13 | 4,481 | B8DPDT7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $95,636.46 | 6,582 | BJ5FZ74 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $94,832.99 | 4,417 | BLB0YH0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $94,403.30 | 4,262 | BV2DHY6 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $91,748.43 | 3,771 | BN7Q7R7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $91,228.20 | 5,684 | BFWLC09 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $90,082.07 | 1,963 | BRXB0C0 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $88,763.73 | 3,201 | BPCQZY9 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $86,753.14 | 2,441 | BJQ05Z6 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $86,262.80 | 2,504 | BCBVTX1 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $86,121.90 | 1,910 | BQKXDX4 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $83,688.75 | 22,317 | BM9FJ13 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,925.37 | 9,307 | BNZB1X8 |
| 0.10% | GRAL | GRAIL INC | -- | $82,900.35 | 1,665 | BSLSSX7 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $80,662.90 | 2,753 | BBC9WC7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $80,517.54 | 1,186 | BDRW1L7 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $80,412.64 | 4,697 | BPCK358 |
| 0.09% | PHVS | PHARVARIS NV | -- | $79,843.60 | 2,740 | BMZ2X38 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $79,801.54 | 2,282 | BMVNDH9 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $78,213.87 | 5,481 | BJH9ZN0 |
| 0.09% | VCEL | VERICEL CORP | -- | $76,823.64 | 2,172 | BSBMN89 |
| 0.09% | INVA | INNOVIVA INC | -- | $75,730.72 | 3,166 | BDDXF67 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $75,447.00 | 5,050 | BYZM6C2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $74,851.69 | 2,039 | BR3T9B6 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $74,600.12 | 4,396 | BMVLGP2 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $74,036.16 | 3,608 | BMX9K07 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $73,267.84 | 958 | BCDWBX6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,290.28 | 2,474 | BKSGZN7 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $70,280.74 | 6,719 | BK4PZ38 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $70,260.00 | 11,710 | BNC1BX1 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $67,277.84 | 17,612 | BF0DMK7 |
| 0.08% | ARDX | ARDELYX INC | -- | $66,049.20 | 10,484 | BN89V40 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $64,233.76 | 2,708 | BQB42F1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $63,250.24 | 1,919 | BQXJKH2 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $62,112.00 | 15,528 | BWJDYK1 |
| 0.07% | HROW | HARROW INC | -- | $61,520.94 | 1,586 | BHNDW86 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $61,091.91 | 8,049 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $60,517.16 | 6,964 | BJDQXG4 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,448.03 | 3,261 | BP7KZP7 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,293.36 | 1,874 | BLCD809 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $59,207.05 | 4,865 | BYSS4X4 |
| 0.07% | PGEN | PRECIGEN INC | -- | $59,003.10 | 15,129 | BKM5C84 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,494.74 | 3,426 | BMZ4LN0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $55,230.45 | 2,057 | BSRK699 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,368.52 | 3,532 | BYP80F1 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $51,938.06 | 1,766 | BMGTLY5 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,912.50 | 621 | BNSP8K3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $51,775.57 | 3,539 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $51,686.52 | 14,122 | BPNTJ34 |
| 0.06% | SVRA | SAVARA INC | -- | $51,074.87 | 8,701 | BYXGN81 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,033.32 | 12,962 | BL53SR3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,604.09 | 1,913 | BQNKXX2 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $49,046.50 | 2,330 | BQB42H3 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $48,463.81 | 881 | BL95N25 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,434.94 | 1,358 | BX7RSN3 |
| 0.05% | GERN | GERON CORP | -- | $46,125.17 | 27,293 | 2370381 |
| 0.05% | QURE | UNIQURE NV | -- | $45,954.00 | 2,664 | BJFSR88 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $45,309.66 | 5,214 | B8K7T65 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $45,099.32 | 2,162 | BD06CS0 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $45,084.00 | 2,652 | BP6C0S2 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $44,121.76 | 4,292 | BKVDFF7 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,989.00 | 7,095 | BLR7H87 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $43,076.72 | 3,368 | BJLKVS6 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $43,020.00 | 2,000 | BZ7PJQ1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $42,037.52 | 1,939 | BNFWZS4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,510.47 | 1,729 | B3X26D8 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,169.85 | 3,997 | BRXYZ57 |
| 0.05% | ANNX | ANNEXON INC | -- | $39,287.45 | 6,187 | BMVV9R5 |
| 0.05% | XNCR | XENCOR INC | -- | $39,243.87 | 3,137 | BGCYWN8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,174.72 | 11,388 | BMFJJ97 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,134.08 | 2,602 | BMFX8Y7 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $38,711.25 | 3,441 | BFYQFJ2 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,763.70 | 2,526 | BM90J52 |
| 0.04% | OMER | OMEROS CORP | -- | $37,117.50 | 3,030 | B4NB858 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,839.04 | 8,223 | BZ0QMB7 |
| 0.04% | MNKD | MANNKIND CORP | -- | $36,491.98 | 13,174 | BF081J4 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $36,075.52 | 2,168 | BMNDK09 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $35,232.75 | 2,237 | BQS7491 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $34,038.00 | 1,464 | BD9GVY0 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,908.56 | 4,228 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,675.05 | 3,721 | BYZD465 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $33,028.08 | 7,243 | BYWVTY5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,513.29 | 1,857 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $31,267.40 | 1,270 | BKLCWZ3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,033.50 | 2,434 | BMFK3H6 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,880.65 | 1,145 | BGL0JK3 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,406.46 | 6,958 | B3MZ6K5 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,013.92 | 2,736 | BDZ30Q0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $29,662.62 | 4,474 | BJQ0608 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $29,251.22 | 7,718 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,730.56 | 3,333 | BQHN6C7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $27,721.20 | 1,777 | BRJJYT3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,910.62 | 777 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,886.00 | 2,300 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,829.92 | 2,406 | BLFBZ32 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,350.64 | 3,368 | BJ0LT31 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $24,042.64 | 4,034 | BMC3HS7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $23,870.76 | 804 | BPBPCG8 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $23,487.75 | 2,847 | BJDX8Z9 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,954.80 | 2,442 | BSMLR16 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,915.62 | 1,638 | BP81RK8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $22,822.80 | 2,310 | BRCFFK6 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,416.03 | 4,641 | BMXNGZ6 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $22,177.40 | 10,220 | BBNBTD2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,111.60 | 5,215 | BYVQJ96 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,903.00 | 6,258 | BMCWKZ2 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,670.56 | 909 | BTNMG41 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,298.60 | 2,180 | BKLXFX5 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,222.80 | 3,121 | BQ6C357 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,851.53 | 9,609 | BFZNYB7 |
| 0.02% | KMDA | KAMADA LTD | -- | $20,821.48 | 2,467 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $20,659.20 | 12,912 | B4N8MH9 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,379.93 | 6,429 | BN94K69 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,264.40 | 2,165 | BZ0G875 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,259.15 | 5,155 | BYV2W40 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,258.37 | 11,847 | BM8NHS1 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,633.32 | 3,339 | BLN9Z50 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,249.35 | 2,715 | BP81R42 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,487.44 | 634 | B292NQ7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,443.99 | 2,537 | B12W3P6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,200.20 | 5,353 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,071.10 | 1,242 | B9L5200 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,010.96 | 4,642 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,251.50 | 1,302 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,261.52 | 2,174 | B7F2TY6 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,098.90 | 3,126 | BP0TQC5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,888.00 | 662 | BS2F741 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,760.75 | 2,741 | BMVBZF5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,258.13 | 1,303 | BM7V485 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,718.70 | 7,145 | BN4JN37 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,610.96 | 2,007 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,396.10 | 3,063 | 2107437 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $14,066.38 | 4,174 | BZ8FPH3 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,987.60 | 4,114 | BK5MWR1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,511.42 | 4,303 | BZC0D70 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,840.12 | 3,963 | BYTYP72 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,825.10 | 2,770 | BDRJH21 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,798.88 | 1,336 | BQV0J03 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,779.73 | 8,577 | BFMLGR4 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,477.40 | 4,799 | BKRRKY7 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,189.61 | 2,503 | BMF7DT9 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $12,057.08 | 4,172 | BKX9NQ0 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $12,013.20 | 6,390 | BRK0149 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,031.98 | 2,414 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,464.68 | 1,214 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,454.40 | 1,980 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,155.60 | 2,520 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,498.06 | 3,861 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $9,107.92 | 6,154 | BN13S71 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,789.00 | 3,995 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,772.75 | 8,355 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $8,608.00 | 1,600 | 2517058 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,344.99 | 3,173 | BPTK6Z2 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $8,052.96 | 3,532 | BDDVW37 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,048.82 | 1,326 | BP2NYN2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,135.59 | 9,267 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,988.45 | 2,435 | BKTV702 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,271.86 | 2,289 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,074.30 | 8,252 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,058.52 | 2,941 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,729.48 | 931 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,553.73 | 2,663 | BLBR8D5 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,461.66 | 9,895 | BJ0CK86 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,004.16 | 4,171 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $29.77 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 37.21% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 31,421,864 | -- | 5,170 | -- |
| 29.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,113,180 | -- | 4,132 | -- |
| 26.64% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,499,756 | -- | 3,702 | -- |
| 18.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 16,039,129 | -- | 2,639 | -- |
| 17.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,586,552 | -- | 2,400 | -- |
| 4.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,847,203 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $29,409,551.99 | 29,409,552 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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