BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,082,231
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/15/2026- NAV
- NAV Change
- Market Price $80.27
- Market Price Change $-4.51
- Trading Volume (M) 7,487
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,082,231
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/15/2026- NAV
- NAV Change
- Market Price $80.27
- Market Price Change $-4.51
- Trading Volume (M) 7,487
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/15/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.92% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,592,165.95 | 8,221 | 2931034 |
| 4.86% | GILD | GILEAD SCIENCES INC | -- | $3,553,342.76 | 27,422 | 2369174 |
| 4.70% | AMGN | AMGEN INC | -- | $3,433,760.13 | 10,523 | 2023607 |
| 3.94% | REGN | REGENERON PHARMACEUTICALS | -- | $2,879,583.00 | 4,124 | 2730190 |
| 2.07% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,510,662.72 | 5,264 | B00FWN1 |
| 1.57% | RVMD | REVOLUTION MEDICINES INC | -- | $1,145,761.56 | 7,866 | BL71K91 |
| 1.54% | BIIB | BIOGEN INC | -- | $1,123,933.75 | 5,825 | 2455965 |
| 1.35% | UTHR | UNITED THERAPEUTICS CORP | -- | $989,329.20 | 1,740 | 2430412 |
| 1.28% | INSM | INSMED INC | -- | $933,801.84 | 8,556 | 2614487 |
| 1.23% | ARGX | ARGENX SE - ADR | -- | $900,034.32 | 1,126 | BDVLM39 |
| 1.23% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $898,714.25 | 17,005 | BMVP7Y0 |
| 1.18% | ILMN | ILLUMINA INC | -- | $865,075.26 | 6,069 | 2613990 |
| 1.14% | ROIV | ROIVANT SCIENCES LTD | -- | $832,070.32 | 28,408 | BMW4NZ9 |
| 1.05% | MRNA | MODERNA INC | -- | $768,751.04 | 15,676 | BGSXTS3 |
| 1.03% | VTRS | VIATRIS INC | -- | $753,152.48 | 45,701 | BMWS3X9 |
| 1.03% | INCY | INCYTE CORP | -- | $752,853.69 | 7,899 | 2471950 |
| 0.86% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $631,145.28 | 3,984 | 2623911 |
| 0.80% | ASND | ASCENDIS PHARMA A/S | -- | $587,782.00 | 2,444 | BWXJHM8 |
| 0.76% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $558,885.11 | 2,443 | B4Q5ZN4 |
| 0.71% | SMMT | SUMMIT THERAPEUTICS INC | -- | $519,191.12 | 30,776 | BMTVQS7 |
| 0.71% | EXEL | EXELIXIS INC | -- | $516,740.04 | 10,308 | 2576941 |
| 0.70% | BBIO | BRIDGEBIO PHARMA INC | -- | $508,870.35 | 7,695 | BK1KWG8 |
| 0.68% | GH | GUARDANT HEALTH INC | -- | $494,153.52 | 5,206 | BFXC911 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $486,726.11 | 6,557 | BDJ0LS6 |
| 0.65% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $477,081.59 | 911 | BD59BS7 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $468,009.29 | 1,127 | BDCBC61 |
| 0.63% | AXSM | AXSOME THERAPEUTICS INC | -- | $462,271.60 | 2,030 | BYZR4X4 |
| 0.58% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $426,131.86 | 5,558 | BYQBFJ8 |
| 0.57% | SNY | SANOFI-ADR | -- | $414,733.35 | 9,715 | 2964557 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $405,213.75 | 4,525 | BK6H543 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $395,517.54 | 7,634 | 2437071 |
| 0.52% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $378,550.90 | 1,105 | BQ721R4 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $372,159.63 | 1,269 | BYYWPW6 |
| 0.51% | CYTK | CYTOKINETICS INC | -- | $370,830.65 | 4,889 | BBBSBJ5 |
| 0.49% | KRYS | KRYSTAL BIOTECH INC | -- | $355,296.40 | 1,160 | BD6JX35 |
| 0.45% | IBRX | IMMUNITYBIO INC | -- | $325,239.76 | 40,808 | BNSP0B8 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $314,390.08 | 4,684 | 2975098 |
| 0.41% | TEM | TEMPUS AI INC-CL A | -- | $302,941.28 | 6,896 | BSLSJJ0 |
| 0.41% | PCVX | VAXCYTE INC | -- | $299,304.07 | 5,713 | BKPVGH6 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $297,181.50 | 2,905 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $279,338.67 | 2,439 | BLC89B2 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $266,442.61 | 3,241 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $258,821.94 | 2,533 | BDCBCD8 |
| 0.34% | ALKS | ALKERMES PLC | -- | $247,930.20 | 6,615 | B3P6D26 |
| 0.34% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $245,309.20 | 2,710 | BF2YWG4 |
| 0.33% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $244,733.08 | 2,395 | BJDX8Y8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $234,850.42 | 3,286 | B17VCN9 |
| 0.32% | SYRE | SPYRE THERAPEUTICS INC | -- | $233,525.64 | 3,117 | BQBBDY8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $224,282.43 | 3,351 | BRBCSP4 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $222,091.71 | 8,079 | BJRFSB7 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $210,524.56 | 6,442 | BLR6XK8 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $199,818.15 | 4,049 | BFZQ0L8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $187,933.73 | 4,747 | BLB0YQ9 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,442.10 | 3,810 | BDHF4K6 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $182,476.64 | 4,964 | BTZRLN8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $179,595.78 | 3,302 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $176,560.64 | 2,176 | BM9HHL5 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $168,862.32 | 792 | 2501578 |
| 0.22% | CAI | CARIS LIFE SCIENCES INC | -- | $162,945.45 | 11,199 | BT18HP9 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $161,748.16 | 4,564 | BP8JSP4 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $155,921.99 | 3,661 | BLFGJD5 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $152,816.12 | 4,156 | BDD19F8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $148,981.84 | 12,488 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $144,813.80 | 6,767 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $140,897.22 | 4,258 | BKY5JZ8 |
| 0.17% | ERAS | ERASCA INC | -- | $125,706.24 | 12,288 | BNLYBF3 |
| 0.17% | VCYT | VERACYTE INC | -- | $121,365.92 | 3,154 | BFTWZY0 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $119,679.78 | 2,434 | BGKG6G7 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $119,629.48 | 3,092 | BQS9486 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $118,967.53 | 1,921 | BKVF0J2 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $117,212.90 | 6,295 | BD2B4V0 |
| 0.16% | ALMS | ALUMIS INC | -- | $114,761.66 | 5,018 | BPLQG36 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $112,990.15 | 6,535 | BN15WD1 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $112,920.99 | 4,043 | BK6L288 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $112,502.68 | 2,276 | B72ZBG4 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $109,913.76 | 5,346 | BP2P6L0 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $105,690.24 | 2,832 | BL55460 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $105,528.72 | 1,689 | BMH5RL1 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $104,958.36 | 4,923 | BKX9VD3 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $102,961.22 | 1,822 | BRXB0C0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $101,292.90 | 1,515 | BMGJZJ8 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $99,025.20 | 4,671 | BKS3RS7 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $98,340.06 | 3,486 | BK0VHF6 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $97,397.04 | 2,356 | BMFD115 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $95,875.00 | 3,835 | BJ62Z18 |
| 0.13% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $92,292.50 | 3,350 | BMX9K07 |
| 0.13% | GRAL | GRAIL INC | -- | $92,278.55 | 1,547 | BSLSSX7 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $89,794.10 | 9,955 | 2100362 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $89,699.46 | 2,423 | BFXC933 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $86,546.80 | 7,094 | BN2R582 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $86,000.58 | 3,141 | BP9N0G0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $83,057.43 | 3,957 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $80,647.84 | 5,278 | BFWLC09 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $79,408.86 | 4,517 | BYSS4X4 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $79,151.56 | 8,641 | BNZB1X8 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $78,450.72 | 2,118 | BMVNDH9 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $78,416.96 | 6,112 | BJ5FZ74 |
| 0.11% | ADMA | ADMA BIOLOGICS INC | -- | $78,176.31 | 9,453 | B9NSBM2 |
| 0.11% | PHVS | PHARVARIS NV | -- | $77,307.20 | 2,543 | BMZ2X38 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $72,990.45 | 4,159 | B8DPDT7 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $72,278.00 | 5,090 | BJH9ZN0 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $71,229.62 | 1,771 | BQKXDX4 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $71,072.10 | 2,970 | BPCQZY9 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $70,825.23 | 3,501 | BN7Q7R7 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $70,136.44 | 1,892 | BR3T9B6 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $69,428.90 | 890 | BCDWBX6 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $69,401.85 | 1,099 | BDRW1L7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $69,086.64 | 2,296 | BKSGZN7 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $68,191.36 | 2,267 | BJQ05Z6 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $67,809.70 | 2,555 | BBC9WC7 |
| 0.09% | QURE | UNIQURE NV | -- | $66,894.65 | 2,473 | BJFSR88 |
| 0.09% | VCEL | VERICEL CORP | -- | $66,555.45 | 2,015 | BSBMN89 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $65,523.42 | 2,326 | BCBVTX1 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $64,797.12 | 10,872 | BNC1BX1 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $64,720.11 | 4,082 | BMVLGP2 |
| 0.09% | INVA | INNOVIVA INC | -- | $64,591.80 | 2,940 | BDDXF67 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,098.63 | 4,689 | BYZM6C2 |
| 0.09% | INBX | INHIBRX BIOSCIENCES INC | -- | $62,685.28 | 577 | BNSP8K3 |
| 0.08% | PGEN | PRECIGEN INC | -- | $62,074.48 | 14,044 | BKM5C84 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,700.81 | 20,717 | BM9FJ13 |
| 0.08% | ARDX | ARDELYX INC | -- | $60,642.82 | 9,734 | BN89V40 |
| 0.08% | NVAX | NOVAVAX INC | -- | $58,591.02 | 6,467 | BJDQXG4 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $57,909.32 | 4,359 | BPCK358 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $57,884.26 | 14,417 | BWJDYK1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $57,825.90 | 1,782 | BQXJKH2 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $56,414.40 | 16,352 | BF0DMK7 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,921.90 | 3,026 | BP7KZP7 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,832.02 | 6,238 | BK4PZ38 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $53,620.38 | 2,006 | BD06CS0 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $53,473.24 | 1,858 | BZ7PJQ1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $52,662.18 | 2,462 | BP6C0S2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $50,878.45 | 2,515 | BQB42F1 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $50,692.26 | 3,711 | BRXYZ57 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $50,585.44 | 7,472 | BYZG9R0 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $49,214.97 | 12,033 | BL53SR3 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $48,835.05 | 1,741 | BLCD809 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $48,819.60 | 1,910 | BSRK699 |
| 0.07% | SEPN | SEPTERNA INC | -- | $47,890.15 | 1,777 | BQNKXX2 |
| 0.06% | HROW | HARROW INC | -- | $45,878.70 | 1,470 | BHNDW86 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,678.93 | 1,639 | BMGTLY5 |
| 0.06% | ALVO | ALVOTECH SA | -- | $43,394.10 | 13,110 | BPNTJ34 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $43,243.38 | 3,182 | BMZ4LN0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,562.80 | 1,260 | BX7RSN3 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,096.64 | 6,586 | BLR7H87 |
| 0.06% | SVRA | SAVARA INC | -- | $40,622.28 | 8,076 | BYXGN81 |
| 0.06% | EYPT | EYEPOINT INC | -- | $40,582.10 | 3,286 | BMGS7L1 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $40,352.18 | 3,278 | BYP80F1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $39,082.54 | 2,131 | BQB42H3 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $38,814.91 | 3,743 | BMC3HS7 |
| 0.05% | MNKD | MANNKIND CORP | -- | $37,787.61 | 12,229 | BF081J4 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,129.36 | 3,128 | BJLKVS6 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $37,089.72 | 4,842 | B8K7T65 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,886.85 | 2,345 | BM90J52 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $36,382.48 | 1,607 | B3X26D8 |
| 0.05% | OMER | OMEROS CORP | -- | $34,471.50 | 2,814 | B4NB858 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $33,544.35 | 2,415 | BMFX8Y7 |
| 0.04% | GERN | GERON CORP | -- | $32,686.02 | 25,338 | 2370381 |
| 0.04% | XNCR | XENCOR INC | -- | $32,661.42 | 2,911 | BGCYWN8 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $32,618.42 | 2,011 | BMNDK09 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $32,490.57 | 2,261 | BMFK3H6 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $32,461.45 | 3,983 | BKVDFF7 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $32,459.11 | 10,573 | BMFJJ97 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,368.16 | 7,634 | BZ0QMB7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,196.64 | 1,064 | BGL0JK3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,845.88 | 3,454 | BYZD465 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,149.22 | 2,078 | BQS7491 |
| 0.04% | ABSI | ABSCI CORP | -- | $30,620.97 | 5,969 | BN94K69 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,445.84 | 1,724 | BT9K6D8 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,382.87 | 1,801 | BNFWZS4 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,033.00 | 3,195 | BFYQFJ2 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,931.45 | 5,745 | BMVV9R5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $29,605.68 | 9,489 | BBNBTD2 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $29,135.70 | 3,924 | BMCR7V2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $28,149.03 | 819 | BL95N25 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $28,022.99 | 1,361 | BD9GVY0 |
| 0.04% | PSNL | PERSONALIS INC | -- | $26,413.08 | 4,153 | BJQ0608 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $25,494.39 | 2,907 | BP0TQC5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,607.35 | 2,235 | BLFBZ32 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $24,277.25 | 6,725 | BYWVTY5 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,111.50 | 5,810 | BMCWKZ2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,110.24 | 1,648 | BRJJYT3 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,608.85 | 3,127 | BJ0LT31 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,169.76 | 6,472 | B3MZ6K5 |
| 0.03% | ARVN | ARVINAS INC | -- | $23,054.12 | 2,539 | BDZ30Q0 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,573.40 | 1,180 | BKLCWZ3 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,637.24 | 4,787 | BYV2W40 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $21,523.32 | 2,268 | BSMLR16 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $21,396.64 | 3,092 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $20,993.45 | 7,165 | BPBJFM7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,887.20 | 720 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $20,857.12 | 2,137 | B91XRN2 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,778.05 | 745 | BPBPCG8 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,195.31 | 4,843 | BYVQJ96 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $19,512.54 | 2,521 | BP81R42 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $19,498.05 | 2,145 | BRCFFK6 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $18,573.10 | 1,099 | BS2CR64 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,528.75 | 2,025 | BKLXFX5 |
| 0.03% | NGNE | NEUROGENE INC | -- | $18,339.30 | 615 | BS2F741 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,840.00 | 8,920 | BFZNYB7 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $17,688.36 | 2,644 | BJDX8Z9 |
| 0.02% | KMDA | KAMADA LTD | -- | $17,655.90 | 2,290 | B2Q9833 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $17,105.94 | 3,277 | BDDVW37 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,724.50 | 2,573 | BDRJH21 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,573.76 | 1,208 | BPRBTY7 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,905.40 | 588 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,448.32 | 1,152 | B9L5200 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $15,429.80 | 4,310 | BMXNGZ6 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $15,106.56 | 843 | BTNMG41 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $14,745.73 | 2,897 | BQ6C357 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,732.88 | 2,346 | B12W3P6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,167.35 | 4,971 | BFY7DC4 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $14,004.25 | 4,309 | BDFKQ07 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,971.48 | 2,019 | B7F2TY6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,787.88 | 3,873 | BKX9NQ0 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,425.44 | 11,987 | B4N8MH9 |
| 0.02% | IVVD | INVIVYD INC | -- | $13,310.00 | 11,000 | BM8NHS1 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,225.08 | 2,563 | BMVBZF5 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,978.06 | 7,962 | BFMLGR4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,714.10 | 3,101 | BLN9Z50 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,694.50 | 1,209 | BM7V485 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $12,647.51 | 3,821 | BK5MWR1 |
| 0.02% | OABI | OMNIAB INC | -- | $12,456.52 | 5,714 | BN13S71 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $12,202.88 | 6,632 | BN4JN37 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,851.14 | 2,842 | 2107437 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,491.48 | 2,009 | BZ0G875 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,370.40 | 1,864 | BL5B6Z1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,140.47 | 3,993 | BZC0D70 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $10,702.98 | 3,678 | BYTYP72 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,152.50 | 3,875 | BZ8FPH3 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,697.60 | 1,520 | BP81RK8 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,314.81 | 5,933 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $9,116.28 | 1,242 | BQV0J03 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,819.10 | 3,585 | B5LL2C2 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,811.75 | 2,325 | BMF7DT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,806.34 | 2,339 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,493.90 | 1,231 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,426.16 | 1,128 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,336.52 | 2,241 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,183.55 | 1,839 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $8,108.10 | 4,455 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,939.40 | 3,710 | BNYJR68 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,458.75 | 2,125 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,376.21 | 8,604 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,124.57 | 7,660 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,908.96 | 7,762 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,542.80 | 1,487 | 2517058 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,217.75 | 2,261 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,923.47 | 2,947 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,633.88 | 2,471 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,229.95 | 2,729 | BMTX3D7 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $4,181.76 | 3,872 | BNNXX18 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $3,948.48 | 864 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,123.58 | 9,187 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 33.07% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 24,164,215 | -- | 4,148 | -- |
| 28.09% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,529,097 | -- | 3,524 | -- |
| 26.90% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,655,271 | -- | 3,374 | -- |
| 21.04% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,373,521 | -- | 2,639 | -- |
| 20.03% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,639,507 | -- | 2,513 | -- |
| 5.05% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,687,548 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $19,591,427.91 | 19,591,428 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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