BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,818,340
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/04/2026- NAV
- NAV Change
- Market Price $82.54
- Market Price Change $+2.78
- Trading Volume (M) 5,926
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,818,340
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/04/2026- NAV
- NAV Change
- Market Price $82.54
- Market Price Change $+2.78
- Trading Volume (M) 5,926
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/04/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.86% | GILD | GILEAD SCIENCES INC | -- | $3,731,375.49 | 28,121 | 2369174 |
| 4.72% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,623,205.65 | 8,429 | 2931034 |
| 4.55% | AMGN | AMGEN INC | -- | $3,494,665.35 | 10,791 | 2023607 |
| 3.90% | REGN | REGENERON PHARMACEUTICALS | -- | $2,997,830.67 | 4,227 | 2730190 |
| 2.09% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,607,603.30 | 5,396 | B00FWN1 |
| 1.60% | INSM | INSMED INC | -- | $1,228,307.73 | 8,773 | 2614487 |
| 1.55% | RVMD | REVOLUTION MEDICINES INC | -- | $1,192,813.50 | 8,065 | BL71K91 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,117,830.91 | 5,971 | 2455965 |
| 1.35% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,036,315.26 | 1,783 | 2430412 |
| 1.22% | ARGX | ARGENX SE - ADR | -- | $936,808.95 | 1,155 | BDVLM39 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $875,287.20 | 17,436 | BMVP7Y0 |
| 1.13% | ILMN | ILLUMINA INC | -- | $867,438.88 | 6,224 | 2613990 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $826,240.24 | 29,134 | BMW4NZ9 |
| 1.02% | INCY | INCYTE CORP | -- | $787,028.28 | 8,102 | 2471950 |
| 0.99% | MRNA | MODERNA INC | -- | $760,252.90 | 16,073 | BGSXTS3 |
| 0.93% | VTRS | VIATRIS INC | -- | $712,348.00 | 46,865 | BMWS3X9 |
| 0.75% | ASND | ASCENDIS PHARMA A/S | -- | $572,918.55 | 2,505 | BWXJHM8 |
| 0.71% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $547,810.02 | 4,086 | 2623911 |
| 0.71% | BBIO | BRIDGEBIO PHARMA INC | -- | $544,400.09 | 7,891 | BK1KWG8 |
| 0.70% | SMMT | SUMMIT THERAPEUTICS INC | -- | $535,888.80 | 31,560 | BMTVQS7 |
| 0.68% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $521,190.30 | 2,505 | B4Q5ZN4 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $507,401.25 | 6,725 | BDJ0LS6 |
| 0.63% | GH | GUARDANT HEALTH INC | -- | $486,574.29 | 5,337 | BFXC911 |
| 0.63% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $484,428.44 | 934 | BD59BS7 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $481,658.10 | 1,155 | BDCBC61 |
| 0.61% | EXEL | EXELIXIS INC | -- | $466,921.07 | 10,571 | 2576941 |
| 0.61% | AXSM | AXSOME THERAPEUTICS INC | -- | $465,743.40 | 2,082 | BYZR4X4 |
| 0.60% | BNTX | BIONTECH SE-ADR | -- | $460,685.95 | 4,637 | BK6H543 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $435,575.78 | 5,702 | BYQBFJ8 |
| 0.57% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $434,140.88 | 7,828 | 2437071 |
| 0.56% | SNY | SANOFI-ADR | -- | $431,766.00 | 9,960 | 2964557 |
| 0.51% | TEM | TEMPUS AI INC-CL A | -- | $394,576.70 | 7,070 | BSLSJJ0 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $386,579.14 | 1,301 | BYYWPW6 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $382,849.74 | 1,134 | BQ721R4 |
| 0.45% | PCVX | VAXCYTE INC | -- | $342,575.93 | 5,857 | BKPVGH6 |
| 0.45% | KRYS | KRYSTAL BIOTECH INC | -- | $342,044.40 | 1,192 | BD6JX35 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $331,174.70 | 5,014 | BBBSBJ5 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $310,938.07 | 41,849 | BNSP0B8 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $310,194.28 | 4,804 | 2975098 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $305,807.60 | 2,980 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $292,707.87 | 2,499 | BLC89B2 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $277,602.39 | 3,321 | BMPRZV5 |
| 0.34% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $259,820.24 | 2,456 | BJDX8Y8 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $258,552.96 | 2,598 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $242,711.84 | 6,608 | BLR6XK8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $237,912.40 | 2,780 | BF2YWG4 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $232,684.90 | 3,437 | BRBCSP4 |
| 0.30% | ALKS | ALKERMES PLC | -- | $231,809.28 | 6,784 | B3P6D26 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $230,792.95 | 8,287 | BJRFSB7 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $220,939.48 | 3,196 | BQBBDY8 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $220,570.32 | 3,368 | B17VCN9 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $214,673.34 | 11,486 | BT18HP9 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,166.91 | 5,203 | BYTQ6X1 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $209,337.06 | 3,907 | BDHF4K6 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $198,330.24 | 5,088 | BTZRLN8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $194,356.40 | 3,386 | BRJ3GY4 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $193,299.30 | 4,869 | BLB0YQ9 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $193,077.92 | 4,154 | BFZQ0L8 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $186,400.05 | 2,231 | BM9HHL5 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $184,971.60 | 810 | 2501578 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $175,807.50 | 4,262 | BDD19F8 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $168,637.05 | 3,755 | BLFGJD5 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $167,886.66 | 12,806 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $153,932.03 | 6,937 | 2713317 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $140,250.24 | 2,496 | BGKG6G7 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $139,685.08 | 4,678 | BP8JSP4 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $137,310.70 | 4,366 | BKY5JZ8 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $136,565.92 | 3,173 | BQS9486 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $130,926.20 | 1,970 | BKVF0J2 |
| 0.17% | ALMS | ALUMIS INC | -- | $129,936.50 | 5,146 | BPLQG36 |
| 0.17% | ERAS | ERASCA INC | -- | $127,794.42 | 12,603 | BNLYBF3 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $124,741.76 | 4,147 | BK6L288 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $124,496.22 | 5,482 | BP2P6L0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $120,496.18 | 6,454 | BD2B4V0 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $118,657.00 | 6,700 | BN15WD1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $118,483.56 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $113,502.42 | 2,334 | B72ZBG4 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $111,835.24 | 1,732 | BMH5RL1 |
| 0.14% | VCYT | VERACYTE INC | -- | $108,277.65 | 3,237 | BFTWZY0 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $107,749.40 | 1,870 | BRXB0C0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $105,112.56 | 1,554 | BMGJZJ8 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $104,973.84 | 2,484 | BFXC933 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $103,660.20 | 4,788 | BKS3RS7 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $103,317.50 | 3,575 | BK0VHF6 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $103,121.04 | 2,904 | BL55460 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $100,571.37 | 2,417 | BMFD115 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $99,955.45 | 9,695 | B9NSBM2 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,577.73 | 3,933 | BJ62Z18 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $95,532.30 | 3,222 | BP9N0G0 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $95,229.75 | 7,275 | BN2R582 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $94,022.64 | 4,266 | B8DPDT7 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $93,932.00 | 10,210 | 2100362 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $91,027.50 | 3,435 | BMX9K07 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $90,871.50 | 6,267 | BJ5FZ74 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $88,261.50 | 4,058 | BV2DHY6 |
| 0.11% | GRAL | GRAIL INC | -- | $88,165.44 | 1,584 | BSLSSX7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $86,571.97 | 8,861 | BNZB1X8 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $85,347.24 | 5,412 | BFWLC09 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $81,625.44 | 3,048 | BPCQZY9 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $79,434.32 | 2,324 | BJQ05Z6 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $78,781.62 | 1,129 | BDRW1L7 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $78,419.76 | 4,632 | BYSS4X4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,292.16 | 2,608 | BMZ2X38 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $76,749.45 | 2,355 | BKSGZN7 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $76,324.08 | 2,172 | BMVNDH9 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $75,618.45 | 591 | BNSP8K3 |
| 0.10% | VCEL | VERICEL CORP | -- | $75,424.83 | 2,067 | BSBMN89 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,158.16 | 913 | BCDWBX6 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $75,034.84 | 5,218 | BJH9ZN0 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $74,785.92 | 21,246 | BM9FJ13 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $74,022.72 | 11,148 | BNC1BX1 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $73,609.12 | 4,472 | BPCK358 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $73,538.10 | 1,818 | BQKXDX4 |
| 0.09% | ARDX | ARDELYX INC | -- | $72,861.30 | 9,981 | BN89V40 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $71,676.36 | 3,591 | BN7Q7R7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $70,871.84 | 2,621 | BBC9WC7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $70,868.98 | 4,186 | BMVLGP2 |
| 0.09% | INVA | INNOVIVA INC | -- | $69,291.86 | 3,014 | BDDXF67 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $68,963.73 | 1,941 | BR3T9B6 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $66,686.96 | 4,808 | BYZM6C2 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $65,703.04 | 2,384 | BCBVTX1 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $65,111.28 | 6,396 | BK4PZ38 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $64,556.80 | 16,768 | BF0DMK7 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $62,088.60 | 14,783 | BWJDYK1 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $60,764.85 | 3,105 | BP7KZP7 |
| 0.08% | HROW | HARROW INC | -- | $60,742.20 | 1,511 | BHNDW86 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,632.56 | 14,404 | BKM5C84 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $58,594.88 | 2,579 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $57,242.61 | 7,663 | BYZG9R0 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $56,640.60 | 12,340 | BL53SR3 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,866.28 | 2,058 | BD06CS0 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $54,788.94 | 2,526 | BP6C0S2 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,859.24 | 3,362 | BYP80F1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $53,757.44 | 1,826 | BQXJKH2 |
| 0.07% | NVAX | NOVAVAX INC | -- | $53,230.87 | 6,629 | BJDQXG4 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $52,728.94 | 1,958 | BSRK699 |
| 0.07% | QURE | UNIQURE NV | -- | $52,444.48 | 2,536 | BJFSR88 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $51,099.16 | 1,682 | BMGTLY5 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $50,879.68 | 1,784 | BLCD809 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $47,841.64 | 2,219 | BQB42H3 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $47,708.43 | 3,261 | BMZ4LN0 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,326.40 | 13,445 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $46,660.65 | 3,369 | BMGS7L1 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $46,611.25 | 3,805 | BRXYZ57 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $45,876.52 | 839 | BL95N25 |
| 0.06% | SEPN | SEPTERNA INC | -- | $45,197.22 | 1,821 | BQNKXX2 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $44,677.36 | 1,292 | BX7RSN3 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $44,344.16 | 1,904 | BZ7PJQ1 |
| 0.06% | SVRA | SAVARA INC | -- | $43,910.50 | 8,285 | BYXGN81 |
| 0.06% | OMER | OMEROS CORP | -- | $43,000.44 | 2,884 | B4NB858 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,820.36 | 6,754 | BLR7H87 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,978.04 | 1,846 | BNFWZS4 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $41,261.22 | 3,206 | BJLKVS6 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,845.49 | 4,963 | B8K7T65 |
| 0.05% | GERN | GERON CORP | -- | $40,796.45 | 25,985 | 2370381 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,615.05 | 1,645 | B3X26D8 |
| 0.05% | XNCR | XENCOR INC | -- | $39,906.32 | 2,987 | BGCYWN8 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,348.18 | 4,086 | BKVDFF7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,974.63 | 10,843 | BMFJJ97 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,908.04 | 2,406 | BM90J52 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $36,556.80 | 3,840 | BMC3HS7 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,718.34 | 2,477 | BMFX8Y7 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $35,540.75 | 4,025 | BMCR7V2 |
| 0.05% | MNKD | MANNKIND CORP | -- | $35,243.02 | 12,542 | BF081J4 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,902.24 | 2,064 | BMNDK09 |
| 0.04% | ABSI | ABSCI CORP | -- | $34,400.02 | 6,121 | BN94K69 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $34,364.92 | 7,828 | BZ0QMB7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,064.00 | 2,129 | BQS7491 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,519.79 | 5,891 | BMVV9R5 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,904.56 | 1,091 | BGL0JK3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,763.50 | 3,542 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,777.20 | 3,276 | BFYQFJ2 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,879.20 | 1,210 | BKLCWZ3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,514.89 | 2,317 | BMFK3H6 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $30,399.57 | 6,623 | B3MZ6K5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,354.48 | 9,729 | BBNBTD2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $29,601.90 | 1,395 | BD9GVY0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $29,367.54 | 1,767 | BT9K6D8 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $28,825.28 | 6,896 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $28,071.12 | 2,604 | BDZ30Q0 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $25,494.09 | 7,347 | BPBJFM7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,327.40 | 3,206 | BJ0LT31 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,128.10 | 4,259 | BJQ0608 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,904.03 | 1,693 | BRJJYT3 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $24,632.40 | 1,560 | BP81RK8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,619.31 | 2,189 | B91XRN2 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $23,200.95 | 1,129 | BS2CR64 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,014.50 | 2,290 | BLFBZ32 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,948.02 | 3,174 | BQHN6C7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,682.25 | 765 | BPBPCG8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $22,580.82 | 5,958 | BMCWKZ2 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,409.28 | 2,976 | BP0TQC5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,228.71 | 4,907 | BYV2W40 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,889.14 | 741 | BQD3J33 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $21,576.40 | 2,584 | BP81R42 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,948.08 | 4,964 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,925.00 | 2,325 | BSMLR16 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,674.48 | 9,148 | BFZNYB7 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,472.69 | 2,199 | BRCFFK6 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,588.00 | 2,075 | BKLXFX5 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,464.92 | 2,348 | B2Q9833 |
| 0.03% | RGNX | REGENXBIO INC | -- | $19,352.79 | 2,061 | BZ0G875 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,052.60 | 12,292 | B4N8MH9 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,024.20 | 2,710 | BJDX8Z9 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $18,648.18 | 4,419 | BMXNGZ6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,272.52 | 2,417 | B12W3P6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $18,114.60 | 3,178 | BLN9Z50 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,922.80 | 865 | BTNMG41 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,750.38 | 629 | BS2F741 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,531.85 | 1,239 | BPRBTY7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,231.80 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,189.84 | 604 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,186.28 | 1,182 | B9L5200 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,578.66 | 11,278 | BM8NHS1 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,956.20 | 4,420 | BDFKQ07 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,714.93 | 6,803 | BN4JN37 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,579.57 | 2,069 | B7F2TY6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $15,389.92 | 5,096 | BFY7DC4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,998.28 | 3,916 | BK5MWR1 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,720.04 | 2,638 | BDRJH21 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,520.40 | 1,240 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,049.47 | 2,609 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,931.19 | 1,911 | BL5B6Z1 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,501.08 | 2,916 | 2107437 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,869.34 | 3,774 | BYTYP72 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,820.62 | 8,166 | BFMLGR4 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,495.85 | 4,097 | BZC0D70 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,055.02 | 3,972 | BKX9NQ0 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,922.00 | 3,974 | BZ8FPH3 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,813.44 | 1,273 | BQV0J03 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,152.44 | 2,383 | BMF7DT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,965.60 | 4,569 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,525.32 | 6,084 | BRK0149 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $10,186.86 | 3,362 | BDDVW37 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $9,977.70 | 1,263 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,915.49 | 1,157 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,312.00 | 2,400 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,306.96 | 1,884 | BKDQKM6 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,237.96 | 2,298 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,226.76 | 3,676 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $8,259.78 | 5,858 | BN13S71 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,822.61 | 2,179 | BP7L561 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,812.99 | 1,523 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,727.31 | 7,954 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,266.15 | 7,857 | BMYTJP4 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,263.73 | 3,803 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,970.17 | 8,823 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,372.20 | 3,020 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,258.60 | 2,318 | BKTV702 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,040.00 | 2,800 | BMTX3D7 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,669.22 | 886 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,461.60 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,701.77 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,300.42 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.22% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 27,051,225 | -- | 4,585 | -- |
| 29.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,708,869 | -- | 3,849 | -- |
| 27.07% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,791,389 | -- | 3,524 | -- |
| 20.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,569,942 | -- | 2,639 | -- |
| 16.90% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,985,768 | -- | 2,201 | -- |
| 4.86% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,734,662 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,261,986.47 | 26,261,986 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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