BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 8/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.47% | 28.93% | 1.11% | 9.77% | -16.62% | 3.73% | -4.43% | -2.92% | 14.03% | 04/07/2010 |
| BIB NAV | 9.35% | 28.93% | 1.18% | 9.85% | -16.62% | 3.78% | -4.40% | -2.92% | 14.03% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/16/2025- NAV $56.59
- NAV Change $+0.03
- Market Price $56.55
- Market Price Change $-0.01
- Trading Volume (M) 4,833
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/16/2025- NAV $56.59
- NAV Change $+0.03
- Market Price $56.55
- Market Price Change $-0.01
- Trading Volume (M) 4,833
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/16/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.46% | GILD | GILEAD SCIENCES INC | -- | $2,449,008.26 | 22,091 | 2369174 |
| 4.20% | AMGN | AMGEN INC | -- | $2,304,291.23 | 8,438 | 2023607 |
| 3.92% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,152,480.00 | 5,500 | 2931034 |
| 3.87% | REGN | REGENERON PHARMACEUTICALS | -- | $2,125,421.76 | 3,696 | 2730190 |
| 3.36% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,842,192.56 | 3,994 | B00FWN1 |
| 2.93% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,609,990.48 | 20,758 | 2989044 |
| 1.69% | INSM | INSMED INC | -- | $926,834.25 | 6,403 | 2614487 |
| 1.52% | ARGX | ARGENX SE - ADR | -- | $833,570.56 | 1,108 | BDVLM39 |
| 1.35% | BIIB | BIOGEN INC | -- | $739,952.00 | 5,150 | 2455965 |
| 1.15% | UTHR | UNITED THERAPEUTICS CORP | -- | $630,384.48 | 1,584 | 2430412 |
| 1.04% | INCY | INCYTE CORP | -- | $570,687.80 | 6,802 | 2471950 |
| 1.03% | ILMN | ILLUMINA INC | -- | $564,533.24 | 5,563 | 2613990 |
| 0.96% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $524,534.78 | 14,809 | BMVP7Y0 |
| 0.94% | TEM | TEMPUS AI INC | -- | $514,232.32 | 5,908 | BSLSJJ0 |
| 0.90% | MEDP | MEDPACE HOLDINGS INC | -- | $496,168.47 | 1,011 | BDCBC61 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $490,191.10 | 3,479 | 2623911 |
| 0.87% | ONC | BEONE MEDICINES LTD-ADR | -- | $475,421.60 | 1,453 | BYYWPW6 |
| 0.86% | SMMT | SUMMIT THERAPEUTICS INC | -- | $472,968.24 | 26,102 | BMTVQS7 |
| 0.84% | SNY | SANOFI-ADR | -- | $463,492.26 | 9,891 | 2964557 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $420,899.49 | 2,134 | BV9G6B8 |
| 0.72% | VTRS | VIATRIS INC | -- | $394,369.12 | 41,252 | BMWS3X9 |
| 0.68% | EXEL | EXELIXIS INC | -- | $375,117.76 | 9,584 | 2576941 |
| 0.66% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $363,501.66 | 6,739 | 2437071 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $348,402.60 | 3,510 | BK6H543 |
| 0.63% | BBIO | BRIDGEBIO PHARMA INC | -- | $343,541.28 | 6,672 | BK1KWG8 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $343,057.43 | 5,595 | BDJ0LS6 |
| 0.62% | ROIV | ROIVANT SCIENCES LTD | -- | $338,816.92 | 23,894 | BMW4NZ9 |
| 0.62% | MRNA | MODERNA INC | -- | $337,650.12 | 13,593 | BGSXTS3 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $332,671.95 | 779 | BD59BS7 |
| 0.60% | HALO | HALOZYME THERAPEUTICS INC | -- | $328,430.50 | 4,330 | 2975098 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $293,624.01 | 2,763 | BYWPZK5 |
| 0.53% | RVMD | REVOLUTION MEDICINES INC | -- | $292,561.50 | 6,545 | BL71K91 |
| 0.50% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $274,212.18 | 2,167 | B4Q5ZN4 |
| 0.44% | GH | GUARDANT HEALTH INC | -- | $241,267.00 | 4,355 | BFXC911 |
| 0.39% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $213,571.54 | 2,236 | BF2YWG4 |
| 0.38% | CYTK | CYTOKINETICS INC | -- | $208,792.96 | 4,196 | BBBSBJ5 |
| 0.36% | AXSM | AXSOME THERAPEUTICS INC | -- | $197,393.00 | 1,730 | BYZR4X4 |
| 0.34% | CRSP | CRISPR THERAPEUTICS AG | -- | $185,711.65 | 3,035 | BDHF4K6 |
| 0.33% | NUVL | NUVALENT INC-A | -- | $182,587.23 | 2,331 | BMVBZD3 |
| 0.32% | RNA | AVIDITY BIOSCIENCES INC | -- | $175,622.72 | 4,238 | BMWHPY1 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $166,236.65 | 2,785 | B17VCN9 |
| 0.30% | MRUS | MERUS NV | -- | $162,834.60 | 2,434 | BZBY005 |
| 0.29% | ALKS | ALKERMES PLC | -- | $158,916.78 | 5,802 | B3P6D26 |
| 0.29% | KRYS | KRYSTAL BIOTECH INC | -- | $157,004.46 | 1,017 | BD6JX35 |
| 0.27% | ACLX | ARCELLX INC | -- | $149,904.30 | 1,938 | BPCJ1Q2 |
| 0.26% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $142,834.10 | 4,855 | BYQBFJ8 |
| 0.26% | PCVX | VAXCYTE INC | -- | $141,628.05 | 4,535 | BKPVGH6 |
| 0.26% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $140,932.72 | 5,882 | 2713317 |
| 0.24% | ADMA | ADMA BIOLOGICS INC | -- | $131,670.48 | 8,392 | B9NSBM2 |
| 0.23% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $128,468.39 | 1,741 | BJDX8Y8 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $127,667.61 | 2,179 | BDCBCD8 |
| 0.22% | AKRO | AKERO THERAPEUTICS INC | -- | $119,407.80 | 2,803 | BK7Y2V9 |
| 0.21% | LGND | LIGAND PHARMACEUTICALS | -- | $112,710.72 | 678 | 2501578 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $112,291.30 | 3,293 | BDD19F8 |
| 0.20% | KYMR | KYMERA THERAPEUTICS INC | -- | $111,608.64 | 2,288 | BMPRZV5 |
| 0.20% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $107,886.24 | 3,336 | BFZQ0L8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $107,276.36 | 11,014 | BFNF1D6 |
| 0.19% | APLS | APELLIS PHARMACEUTICALS INC | -- | $105,236.76 | 4,418 | BYTQ6X1 |
| 0.18% | INDV | INDIVIOR PLC | -- | $99,823.68 | 4,384 | BP0BQQ5 |
| 0.18% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $98,624.48 | 2,872 | BMX9K07 |
| 0.18% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,903.08 | 3,321 | BJ62Z18 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $96,706.88 | 3,944 | BP8JSP4 |
| 0.18% | XENE | XENON PHARMACEUTICALS INC | -- | $96,246.34 | 2,699 | BRJ3GY4 |
| 0.17% | CGON | CG ONCOLOGY INC | -- | $95,836.80 | 2,680 | BRBCSP4 |
| 0.17% | IMVT | IMMUNOVANT INC | -- | $91,847.03 | 6,007 | BJRFSB7 |
| 0.16% | VCYT | VERACYTE INC | -- | $88,899.12 | 2,754 | BFTWZY0 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $87,171.82 | 31,022 | BNSP0B8 |
| 0.16% | FOLD | AMICUS THERAPEUTICS INC | -- | $86,708.25 | 10,825 | B19FQ48 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $86,528.33 | 1,967 | B72ZBG4 |
| 0.16% | MLYS | MINERALYS THERAPEUTICS INC | -- | $85,691.80 | 2,290 | BP9N0G0 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $81,009.76 | 3,536 | BK6L288 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $76,063.44 | 3,077 | BK0VHF6 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,725.20 | 2,035 | BCBVTX1 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $74,685.60 | 1,476 | BMH5RL1 |
| 0.14% | ALVO | ALVOTECH SA | -- | $74,656.84 | 9,379 | BPNTJ34 |
| 0.14% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,333.10 | 762 | BCDWBX6 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $73,373.44 | 1,216 | BMGJZJ8 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $71,604.81 | 3,357 | BLB0YQ9 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $71,110.71 | 3,123 | BLFGJD5 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $71,070.36 | 4,188 | BKX9VD3 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $69,636.00 | 5,600 | BNZB1X8 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $68,939.40 | 5,340 | BJ5FZ74 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $67,997.16 | 14,049 | BM9FJ13 |
| 0.12% | DNLI | DENALI THERAPEUTICS INC | -- | $67,771.86 | 5,111 | BD2B4V0 |
| 0.12% | ZLAB | ZAI LAB LTD-ADR | -- | $65,698.20 | 2,034 | BD9GVY0 |
| 0.12% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,096.64 | 2,016 | BKSGZN7 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $62,499.30 | 3,453 | B8DPDT7 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $59,533.44 | 1,616 | BM9HHL5 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $59,432.44 | 4,747 | BFWLC09 |
| 0.11% | VCEL | VERICEL CORP | -- | $58,750.64 | 1,768 | BSBMN89 |
| 0.10% | MNKD | MANNKIND CORP | -- | $57,367.71 | 10,683 | BF081J4 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $57,030.48 | 2,106 | BGKG6G7 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $56,985.75 | 7,353 | 2100362 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $55,511.92 | 2,242 | BL55460 |
| 0.10% | HROW | HARROW INC | -- | $55,278.77 | 1,289 | BHNDW86 |
| 0.10% | ARDX | ARDELYX INC | -- | $53,972.94 | 8,407 | BN89V40 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $53,225.76 | 1,488 | BRXB0C0 |
| 0.10% | AVDL | AVADEL PHARMACEUTICALS | -- | $52,378.59 | 3,399 | BDGMC59 |
| 0.09% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $51,937.64 | 3,694 | BKY5JZ8 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $51,921.03 | 3,997 | BN15WD1 |
| 0.09% | TXG | 10X GENOMICS INC-CLASS A | -- | $51,259.52 | 3,904 | BKS3RS7 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $50,210.16 | 4,004 | BLR6XK8 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,042.07 | 10,491 | BL53SR3 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $49,692.92 | 3,919 | BYSS4X4 |
| 0.09% | GRAL | GRAIL INC | -- | $49,101.81 | 1,266 | BSLSSX7 |
| 0.09% | NVAX | NOVAVAX INC | -- | $48,723.52 | 5,692 | BJDQXG4 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $48,645.98 | 2,078 | BMFX8Y7 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $47,157.98 | 1,395 | BLCD809 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $45,606.47 | 2,093 | BQS9486 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $45,465.92 | 3,023 | BN7Q7R7 |
| 0.08% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $44,712.00 | 1,656 | BNFWZS4 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $44,638.26 | 3,638 | BYZM6C2 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $44,444.04 | 1,919 | BJQ05Z6 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,158.28 | 1,628 | B3X26D8 |
| 0.08% | TRML | TOURMALINE BIO INC | -- | $42,986.71 | 901 | BQ80NC6 |
| 0.08% | INVA | INNOVIVA INC | -- | $42,644.70 | 2,205 | BDDXF67 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,329.20 | 7,912 | BN4RD42 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $42,151.04 | 4,288 | B8K7T65 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,041.16 | 5,628 | BLR7H87 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $41,597.52 | 1,473 | BBC9WC7 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $40,943.70 | 4,221 | BRJZSK0 |
| 0.07% | ETNB | 89BIO INC | -- | $40,886.10 | 5,130 | BK1K484 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $40,835.81 | 989 | BQV0J03 |
| 0.07% | PGEN | PRECIGEN INC | -- | $40,362.64 | 10,376 | BKM5C84 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,286.22 | 1,131 | BX7RSN3 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $38,823.84 | 2,451 | BPCQZY9 |
| 0.07% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $37,494.60 | 3,135 | BPCK358 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $36,957.58 | 5,419 | BYZG9R0 |
| 0.06% | RAPP | RAPPORT THERAPEUTICS INC | -- | $33,575.58 | 1,282 | BR3T9B6 |
| 0.06% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $32,898.40 | 2,419 | BMGS7L1 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $32,473.91 | 3,451 | BMCR7V2 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $32,010.92 | 3,182 | BRXYZ57 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $31,773.32 | 1,724 | BMFD115 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $31,448.04 | 2,122 | BQBBDY8 |
| 0.05% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $29,988.00 | 714 | BQ721R4 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $29,629.60 | 6,734 | BZ0QMB7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $29,291.47 | 1,621 | BZ7PJQ1 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $28,457.00 | 3,575 | BJH9ZN0 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $28,010.85 | 3,811 | BP2P6L0 |
| 0.05% | GERN | GERON CORP | -- | $27,982.50 | 22,386 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $27,853.14 | 714 | BL95N25 |
| 0.05% | QURE | UNIQURE NV | -- | $27,840.28 | 1,924 | BJFSR88 |
| 0.05% | CRMD | CORMEDIX INC | -- | $27,653.74 | 2,386 | BJ0LT31 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $27,250.00 | 2,500 | BKVDFF7 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $26,997.40 | 11,738 | BF0DMK7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $26,922.96 | 2,452 | BJLKVS6 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $26,897.92 | 3,002 | BYTYP72 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $26,057.00 | 9,175 | BNC1BX1 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $25,780.05 | 2,655 | BPQYY97 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $25,409.05 | 3,043 | BYZD465 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $25,340.04 | 3,564 | BLB0YH0 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $24,897.60 | 1,596 | BQS7491 |
| 0.05% | RLAY | RELAY THERAPEUTICS INC | -- | $24,887.38 | 6,026 | BN2R582 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $24,573.70 | 7,927 | BMFJJ97 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,397.33 | 1,759 | BMNDK09 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $23,619.60 | 4,860 | BK4PZ38 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $23,598.00 | 1,748 | BD06CS0 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $23,113.20 | 1,870 | BMVNDH9 |
| 0.04% | NRIX | NURIX THERAPEUTICS INC | -- | $22,619.20 | 2,680 | BMVLGP2 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,591.87 | 2,513 | 2107437 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,562.40 | 1,428 | BM7V485 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,425.60 | 3,072 | BMDJ0C9 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,098.00 | 1,016 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $22,048.62 | 6,074 | BYXGN81 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,002.42 | 629 | BQD3J33 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $21,912.80 | 1,204 | BMGTLY5 |
| 0.04% | XNCR | XENCOR INC | -- | $21,575.86 | 2,503 | BGCYWN8 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $21,556.72 | 4,616 | BPBJFM7 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $20,664.36 | 2,823 | BFYQFJ2 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $20,001.40 | 1,031 | BDRW1L7 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $19,623.30 | 1,317 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $19,611.88 | 2,567 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,298.59 | 6,967 | BBNBTD2 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $18,974.72 | 1,088 | BYXV9H7 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $18,967.56 | 2,404 | BMZ4LN0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $18,226.35 | 3,105 | BJQ0608 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $17,275.95 | 955 | BKC9SX3 |
| 0.03% | ERAS | ERASCA INC | -- | $17,029.89 | 9,959 | BNLYBF3 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,006.04 | 3,492 | BYVQJ96 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,714.44 | 522 | B292NQ7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $16,343.90 | 1,765 | BZ0G875 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $16,279.20 | 3,192 | BMC3HS7 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,679.32 | 2,708 | BDDVW37 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,549.66 | 2,709 | BYP80F1 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,455.04 | 1,894 | B91XRN2 |
| 0.03% | EOLS | EVOLUS INC | -- | $14,761.28 | 2,264 | BDRJH21 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $14,736.84 | 2,724 | BQHN6C7 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $14,620.51 | 5,059 | BMCWKZ2 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,416.41 | 1,983 | BMYRFN8 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $14,040.40 | 12,764 | BWFZX59 |
| 0.03% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $13,981.67 | 2,161 | BP7KZP7 |
| 0.03% | ALMS | ALUMIS INC | -- | $13,977.60 | 3,360 | BPLQG36 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $13,953.72 | 1,922 | BLFBZ32 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $13,712.20 | 2,180 | BP81R42 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $13,550.70 | 510 | BNSP8K3 |
| 0.02% | CGEM | CULLINAN THERAPEUTICS INC | -- | $13,076.91 | 2,079 | BM90J52 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $12,972.81 | 10,547 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,307.75 | 3,787 | BDFKQ07 |
| 0.02% | ABSI | ABSCI CORP | -- | $12,106.80 | 4,484 | BN94K69 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,676.60 | 1,996 | BMFK3H6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $10,898.01 | 1,629 | BKLXFX5 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,779.45 | 1,551 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,525.65 | 705 | BN72KB0 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $10,486.55 | 655 | BPBPCG8 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,425.10 | 1,855 | BYX2Z16 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,349.13 | 2,851 | BFY7DC4 |
| 0.02% | ANNX | ANNEXON INC | -- | $10,221.05 | 3,857 | BMVV9R5 |
| 0.02% | ALEC | ALECTOR INC | -- | $9,695.88 | 3,513 | BJ4LDC4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,589.30 | 1,957 | BMF7DT9 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $9,300.72 | 7,046 | BFMLGR4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,245.58 | 2,073 | B12W3P6 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $9,071.84 | 7,688 | BFZNYB7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,008.00 | 2,252 | BMXNGZ6 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $8,963.66 | 3,529 | BZC0D70 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $8,939.70 | 3,010 | BLN9Z50 |
| 0.02% | NGNE | NEUROGENE INC | -- | $8,754.88 | 502 | BS2F741 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,745.60 | 911 | BQB9HM8 |
| 0.02% | HUMA | HUMACYTE INC | -- | $8,559.64 | 5,452 | BMYTJP4 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $8,526.00 | 5,684 | BN4JN37 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $8,514.77 | 2,497 | BKX9NQ0 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $8,493.08 | 1,879 | BP7L561 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $8,331.52 | 2,944 | BZ8FPH3 |
| 0.02% | OMER | OMEROS CORP | -- | $8,301.80 | 2,060 | B4NB858 |
| 0.02% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,270.50 | 1,946 | BY7RB53 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,012.20 | 1,652 | BL5B6Z1 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $7,391.80 | 5,686 | B3MZ6K5 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,250.88 | 2,912 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $6,924.61 | 4,301 | BN13S71 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $6,874.40 | 520 | BTNMG41 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $6,830.08 | 1,334 | BP81RK8 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $6,074.86 | 1,166 | BQ6C357 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,886.27 | 1,521 | BSMLR16 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,602.40 | 752 | B9L5200 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,532.24 | 3,738 | BKMQF66 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,494.40 | 6,464 | BPG5P75 |
| 0.01% | NKTX | NKARTA INC | -- | $4,865.25 | 2,495 | BK80YJ8 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,775.76 | 2,376 | BMW5LX6 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,464.90 | 2,178 | BLBR8D5 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $3,830.37 | 4,029 | BCZS820 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,300.21 | 2,157 | BMDWW66 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,257.52 | 2,216 | BFDV8K0 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,159.64 | 1,837 | BNLYBJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,670.44 | 1,322 | BNKF6N0 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,646.27 | 2,968 | BF12XC2 |
| -- | PEPG | PEPGEN INC | -- | $2,227.12 | 1,148 | BMTX3D7 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,140.11 | 4,977 | BJL38Z1 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,028.72 | 856 | BMF1LJ7 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,706.55 | 1,101 | BP2TPK4 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,261.75 | 175 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,071.24 | 452 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $804.64 | 428 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 31.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,423,690 | -- | 3,675 | -- |
| 25.97% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 14,256,608 | -- | 3,007 | -- |
| 24.77% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,597,590 | -- | 2,868 | -- |
| 20.70% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 11,359,771 | -- | 2,396 | -- |
| 16.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,121,953 | -- | 1,924 | -- |
| 16.58% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,098,248 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,987,686.10 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $14,961,475.91 | 14,961,476 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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