BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 8/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.47% | 28.93% | 1.11% | 9.77% | -16.62% | 3.73% | -4.43% | -2.92% | 14.03% | 04/07/2010 |
| BIB NAV | 9.35% | 28.93% | 1.18% | 9.85% | -16.62% | 3.78% | -4.40% | -2.92% | 14.03% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/12/2025- NAV $57.15
- NAV Change $-2.13
- Market Price $57.20
- Market Price Change $-2.07
- Trading Volume (M) 6,244
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/12/2025- NAV $57.15
- NAV Change $-2.13
- Market Price $57.20
- Market Price Change $-2.07
- Trading Volume (M) 6,244
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/12/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.53% | GILD | GILEAD SCIENCES INC | -- | $2,513,072.16 | 22,091 | 2369174 |
| 4.21% | AMGN | AMGEN INC | -- | $2,332,178.82 | 8,438 | 2023607 |
| 3.91% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,169,915.00 | 5,500 | 2931034 |
| 3.73% | REGN | REGENERON PHARMACEUTICALS | -- | $2,069,760.00 | 3,696 | 2730190 |
| 3.36% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,860,764.66 | 3,994 | B00FWN1 |
| 2.98% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,651,506.48 | 20,758 | 2989044 |
| 1.69% | INSM | INSMED INC | -- | $934,389.79 | 6,403 | 2614487 |
| 1.51% | ARGX | ARGENX SE - ADR | -- | $838,069.04 | 1,108 | BDVLM39 |
| 1.35% | BIIB | BIOGEN INC | -- | $746,029.00 | 5,150 | 2455965 |
| 1.16% | UTHR | UNITED THERAPEUTICS CORP | -- | $641,551.68 | 1,584 | 2430412 |
| 1.02% | INCY | INCYTE CORP | -- | $565,246.20 | 6,802 | 2471950 |
| 0.97% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $538,455.24 | 14,809 | BMVP7Y0 |
| 0.95% | ILMN | ILLUMINA INC | -- | $529,152.56 | 5,563 | 2613990 |
| 0.92% | TEM | TEMPUS AI INC | -- | $510,333.04 | 5,908 | BSLSJJ0 |
| 0.89% | MEDP | MEDPACE HOLDINGS INC | -- | $496,037.04 | 1,011 | BDCBC61 |
| 0.89% | SMMT | SUMMIT THERAPEUTICS INC | -- | $494,371.88 | 26,102 | BMTVQS7 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $493,565.73 | 3,479 | 2623911 |
| 0.85% | ONC | BEONE MEDICINES LTD-ADR | -- | $471,266.02 | 1,453 | BYYWPW6 |
| 0.84% | SNY | SANOFI-ADR | -- | $465,173.73 | 9,891 | 2964557 |
| 0.75% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $417,367.72 | 2,134 | BV9G6B8 |
| 0.74% | VTRS | VIATRIS INC | -- | $410,869.92 | 41,252 | BMWS3X9 |
| 0.68% | EXEL | EXELIXIS INC | -- | $375,213.60 | 9,584 | 2576941 |
| 0.66% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $364,512.51 | 6,739 | 2437071 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $353,380.20 | 5,595 | BDJ0LS6 |
| 0.62% | BBIO | BRIDGEBIO PHARMA INC | -- | $341,673.12 | 6,672 | BK1KWG8 |
| 0.61% | BNTX | BIONTECH SE-ADR | -- | $339,557.40 | 3,510 | BK6H543 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $336,699.38 | 779 | BD59BS7 |
| 0.61% | ROIV | ROIVANT SCIENCES LTD | -- | $336,427.52 | 23,894 | BMW4NZ9 |
| 0.60% | HALO | HALOZYME THERAPEUTICS INC | -- | $332,977.00 | 4,330 | 2975098 |
| 0.58% | MRNA | MODERNA INC | -- | $319,571.43 | 13,593 | BGSXTS3 |
| 0.55% | RVMD | REVOLUTION MEDICINES INC | -- | $304,669.75 | 6,545 | BL71K91 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $294,066.09 | 2,763 | BYWPZK5 |
| 0.49% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $273,388.72 | 2,167 | B4Q5ZN4 |
| 0.43% | GH | GUARDANT HEALTH INC | -- | $239,067.73 | 4,355 | BFXC911 |
| 0.39% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $215,147.92 | 2,236 | BF2YWG4 |
| 0.39% | CYTK | CYTOKINETICS INC | -- | $214,541.48 | 4,196 | BBBSBJ5 |
| 0.37% | AXSM | AXSOME THERAPEUTICS INC | -- | $204,866.60 | 1,730 | BYZR4X4 |
| 0.34% | RNA | AVIDITY BIOSCIENCES INC | -- | $189,608.12 | 4,238 | BMWHPY1 |
| 0.34% | NUVL | NUVALENT INC-A | -- | $187,575.57 | 2,331 | BMVBZD3 |
| 0.31% | CRSP | CRISPR THERAPEUTICS AG | -- | $170,749.10 | 3,035 | BDHF4K6 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $170,135.65 | 2,785 | B17VCN9 |
| 0.31% | MRUS | MERUS NV | -- | $169,357.72 | 2,434 | BZBY005 |
| 0.28% | ALKS | ALKERMES PLC | -- | $156,479.94 | 5,802 | B3P6D26 |
| 0.27% | ACLX | ARCELLX INC | -- | $147,656.22 | 1,938 | BPCJ1Q2 |
| 0.26% | KRYS | KRYSTAL BIOTECH INC | -- | $146,122.56 | 1,017 | BD6JX35 |
| 0.26% | PCVX | VAXCYTE INC | -- | $145,890.95 | 4,535 | BKPVGH6 |
| 0.26% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $144,290.60 | 4,855 | BYQBFJ8 |
| 0.25% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $138,874.02 | 5,882 | 2713317 |
| 0.24% | ADMA | ADMA BIOLOGICS INC | -- | $135,195.12 | 8,392 | B9NSBM2 |
| 0.23% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $129,373.71 | 1,741 | BJDX8Y8 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $128,255.94 | 2,179 | BDCBCD8 |
| 0.22% | AKRO | AKERO THERAPEUTICS INC | -- | $121,818.38 | 2,803 | BK7Y2V9 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $112,378.50 | 678 | 2501578 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $111,962.00 | 3,293 | BDD19F8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $110,140.00 | 11,014 | BFNF1D6 |
| 0.20% | APLS | APELLIS PHARMACEUTICALS INC | -- | $109,787.30 | 4,418 | BYTQ6X1 |
| 0.19% | KYMR | KYMERA THERAPEUTICS INC | -- | $107,513.12 | 2,288 | BMPRZV5 |
| 0.19% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $105,651.12 | 3,336 | BFZQ0L8 |
| 0.18% | INDV | INDIVIOR PLC | -- | $101,752.64 | 4,384 | BP0BQQ5 |
| 0.18% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $100,659.51 | 3,321 | BJ62Z18 |
| 0.18% | XENE | XENON PHARMACEUTICALS INC | -- | $97,730.79 | 2,699 | BRJ3GY4 |
| 0.18% | IMVT | IMMUNOVANT INC | -- | $97,073.12 | 6,007 | BJRFSB7 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $95,405.36 | 3,944 | BP8JSP4 |
| 0.17% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $95,091.92 | 2,872 | BMX9K07 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $89,419.82 | 1,967 | B72ZBG4 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $89,351.20 | 2,680 | BRBCSP4 |
| 0.16% | FOLD | AMICUS THERAPEUTICS INC | -- | $86,491.75 | 10,825 | B19FQ48 |
| 0.15% | VCYT | VERACYTE INC | -- | $85,043.52 | 2,754 | BFTWZY0 |
| 0.15% | MLYS | MINERALYS THERAPEUTICS INC | -- | $84,959.00 | 2,290 | BP9N0G0 |
| 0.15% | IBRX | IMMUNITYBIO INC | -- | $80,657.20 | 31,022 | BNSP0B8 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $75,724.97 | 3,077 | BK0VHF6 |
| 0.14% | ALVO | ALVOTECH SA | -- | $75,313.37 | 9,379 | BPNTJ34 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,847.30 | 2,035 | BCBVTX1 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $74,455.02 | 762 | BCDWBX6 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $73,296.81 | 3,123 | BLFGJD5 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $73,216.17 | 3,357 | BLB0YQ9 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $72,855.36 | 1,476 | BMH5RL1 |
| 0.13% | BEAM | BEAM THERAPEUTICS INC | -- | $72,841.60 | 3,536 | BK6L288 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $72,741.12 | 1,216 | BMGJZJ8 |
| 0.13% | DNLI | DENALI THERAPEUTICS INC | -- | $72,525.09 | 5,111 | BD2B4V0 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $72,410.52 | 4,188 | BKX9VD3 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,736.00 | 5,600 | BNZB1X8 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $67,856.67 | 14,049 | BM9FJ13 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $67,337.40 | 5,340 | BJ5FZ74 |
| 0.12% | ZLAB | ZAI LAB LTD-ADR | -- | $66,715.20 | 2,034 | BD9GVY0 |
| 0.12% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,298.24 | 2,016 | BKSGZN7 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $60,476.78 | 4,747 | BFWLC09 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $60,047.67 | 3,453 | B8DPDT7 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $59,598.08 | 1,616 | BM9HHL5 |
| 0.11% | MNKD | MANNKIND CORP | -- | $59,504.31 | 10,683 | BF081J4 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $58,162.23 | 7,353 | 2100362 |
| 0.10% | VCEL | VERICEL CORP | -- | $56,894.24 | 1,768 | BSBMN89 |
| 0.10% | ARDX | ARDELYX INC | -- | $55,570.27 | 8,407 | BN89V40 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $55,204.80 | 1,488 | BRXB0C0 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $53,302.86 | 2,106 | BGKG6G7 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $53,292.34 | 2,242 | BL55460 |
| 0.09% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $52,602.56 | 3,694 | BKY5JZ8 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $52,560.55 | 3,997 | BN15WD1 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $52,344.60 | 3,399 | BDGMC59 |
| 0.09% | HROW | HARROW INC | -- | $50,812.38 | 1,289 | BHNDW86 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $50,690.64 | 4,004 | BLR6XK8 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $49,975.90 | 2,078 | BMFX8Y7 |
| 0.09% | TXG | 10X GENOMICS INC-CLASS A | -- | $49,346.56 | 3,904 | BKS3RS7 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,159.80 | 1,395 | BLCD809 |
| 0.09% | GRAL | GRAIL INC | -- | $48,158.64 | 1,266 | BSLSSX7 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $47,615.85 | 3,919 | BYSS4X4 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $47,007.65 | 3,023 | BN7Q7R7 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,894.77 | 10,491 | BL53SR3 |
| 0.08% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $46,467.36 | 1,656 | BNFWZS4 |
| 0.08% | NVAX | NOVAVAX INC | -- | $45,422.16 | 5,692 | BJDQXG4 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $45,019.74 | 1,919 | BJQ05Z6 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,151.36 | 1,628 | B3X26D8 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $43,764.63 | 2,093 | BQS9486 |
| 0.08% | TRML | TOURMALINE BIO INC | -- | $42,896.61 | 901 | BQ80NC6 |
| 0.08% | INVA | INNOVIVA INC | -- | $42,710.85 | 2,205 | BDDXF67 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $42,365.44 | 4,288 | B8K7T65 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,250.08 | 7,912 | BN4RD42 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,208.92 | 1,131 | BX7RSN3 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,153.72 | 5,628 | BLR7H87 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $41,545.96 | 3,638 | BYZM6C2 |
| 0.07% | ETNB | 89BIO INC | -- | $41,399.10 | 5,130 | BK1K484 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $40,978.86 | 1,473 | BBC9WC7 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $40,880.32 | 989 | BQV0J03 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $39,719.61 | 4,221 | BRJZSK0 |
| 0.07% | PGEN | PRECIGEN INC | -- | $39,325.04 | 10,376 | BKM5C84 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $38,578.74 | 2,451 | BPCQZY9 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $37,770.43 | 5,419 | BYZG9R0 |
| 0.07% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $36,522.75 | 3,135 | BPCK358 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,613.53 | 3,451 | BMCR7V2 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $34,411.04 | 1,724 | BMFD115 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $33,209.30 | 2,122 | BQBBDY8 |
| 0.06% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $32,293.65 | 2,419 | BMGS7L1 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $32,138.20 | 3,182 | BRXYZ57 |
| 0.06% | QURE | UNIQURE NV | -- | $31,717.14 | 1,924 | BJFSR88 |
| 0.06% | CRMD | CORMEDIX INC | -- | $30,874.84 | 2,386 | BJ0LT31 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $30,460.32 | 1,282 | BR3T9B6 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $30,458.59 | 1,621 | BZ7PJQ1 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,033.64 | 6,734 | BZ0QMB7 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $29,493.75 | 3,575 | BJH9ZN0 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,031.68 | 2,452 | BJLKVS6 |
| 0.05% | GERN | GERON CORP | -- | $28,430.22 | 22,386 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $28,288.68 | 714 | BL95N25 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $28,167.25 | 9,175 | BNC1BX1 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $28,128.74 | 3,002 | BYTYP72 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,950.00 | 2,500 | BKVDFF7 |
| 0.05% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $26,921.37 | 714 | BQ721R4 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $26,645.26 | 11,738 | BF0DMK7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $25,524.94 | 7,927 | BMFJJ97 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $25,375.68 | 3,564 | BLB0YH0 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $25,153.70 | 1,759 | BMNDK09 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $25,063.20 | 2,655 | BPQYY97 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $24,922.17 | 3,043 | BYZD465 |
| 0.04% | TNGX | TANGO THERAPEUTICS INC | -- | $24,885.83 | 3,811 | BP2P6L0 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $24,489.48 | 1,748 | BD06CS0 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $24,300.00 | 4,860 | BK4PZ38 |
| 0.04% | NRIX | NURIX THERAPEUTICS INC | -- | $24,227.20 | 2,680 | BMVLGP2 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $24,125.40 | 1,031 | BDRW1L7 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $24,043.74 | 6,026 | BN2R582 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,876.84 | 629 | BQD3J33 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $23,730.84 | 1,204 | BMGTLY5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $23,652.72 | 1,596 | BQS7491 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $23,412.40 | 1,870 | BMVNDH9 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,415.96 | 2,513 | 2107437 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,362.48 | 1,428 | BM7V485 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,210.56 | 3,072 | BMDJ0C9 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,762.72 | 1,016 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $21,623.44 | 6,074 | BYXGN81 |
| 0.04% | XNCR | XENCOR INC | -- | $21,525.80 | 2,503 | BGCYWN8 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $21,483.03 | 2,823 | BFYQFJ2 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $20,281.80 | 1,317 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $19,868.58 | 2,567 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,786.28 | 6,967 | BBNBTD2 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $19,507.84 | 1,088 | BYXV9H7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,787.12 | 4,616 | BPBJFM7 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $18,679.08 | 2,404 | BMZ4LN0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $18,164.25 | 3,105 | BJQ0608 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,634.60 | 3,492 | BYVQJ96 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,714.44 | 522 | B292NQ7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $16,598.40 | 3,192 | BMC3HS7 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $16,540.60 | 955 | BKC9SX3 |
| 0.03% | EOLS | EVOLUS INC | -- | $16,278.16 | 2,264 | BDRJH21 |
| 0.03% | RGNX | REGENXBIO INC | -- | $16,238.00 | 1,765 | BZ0G875 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,793.47 | 2,709 | BYP80F1 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,549.74 | 1,894 | B91XRN2 |
| 0.03% | ERAS | ERASCA INC | -- | $15,536.04 | 9,959 | BNLYBF3 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,516.84 | 2,708 | BDDVW37 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $14,895.50 | 1,922 | BLFBZ32 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,733.69 | 1,983 | BMYRFN8 |
| 0.03% | ALMS | ALUMIS INC | -- | $14,683.20 | 3,360 | BPLQG36 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $14,682.36 | 2,724 | BQHN6C7 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $14,678.60 | 12,764 | BWFZX59 |
| 0.03% | INBX | INHIBRX BIOSCIENCES INC | -- | $14,035.20 | 510 | BNSP8K3 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $13,666.69 | 1,591 | BG31GH0 |
| 0.02% | CGEM | CULLINAN THERAPEUTICS INC | -- | $13,575.87 | 2,079 | BM90J52 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $13,507.53 | 5,059 | BMCWKZ2 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $13,472.40 | 2,180 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $12,339.99 | 10,547 | B4N8MH9 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $12,035.88 | 1,996 | BMFK3H6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,966.92 | 3,787 | BDFKQ07 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $11,606.60 | 655 | BPBPCG8 |
| 0.02% | ABSI | ABSCI CORP | -- | $11,434.20 | 4,484 | BN94K69 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $11,093.49 | 1,629 | BKLXFX5 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,965.57 | 1,551 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,582.05 | 705 | BN72KB0 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,443.65 | 1,855 | BYX2Z16 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,394.41 | 2,161 | BP7KZP7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,377.64 | 2,851 | BFY7DC4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,156.83 | 1,957 | BMF7DT9 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $9,723.48 | 7,046 | BFMLGR4 |
| 0.02% | ALEC | ALECTOR INC | -- | $9,660.75 | 3,513 | BJ4LDC4 |
| 0.02% | NGNE | NEUROGENE INC | -- | $9,538.00 | 502 | BS2F741 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $9,451.40 | 3,010 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,349.23 | 2,073 | B12W3P6 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,333.94 | 3,857 | BMVV9R5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,208.08 | 5,684 | BN4JN37 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $8,850.36 | 2,252 | BMXNGZ6 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,818.48 | 911 | BQB9HM8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,687.44 | 7,688 | BFZNYB7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $8,575.47 | 3,529 | BZC0D70 |
| 0.02% | OMER | OMEROS CORP | -- | $8,549.00 | 2,060 | B4NB858 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $8,361.55 | 1,879 | BP7L561 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,134.28 | 1,946 | BY7RB53 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,014.44 | 5,452 | BMYTJP4 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,919.36 | 2,944 | BZ8FPH3 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $7,450.52 | 1,652 | BL5B6Z1 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $7,448.66 | 5,686 | B3MZ6K5 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,076.16 | 2,912 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $7,053.64 | 4,301 | BN13S71 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,043.52 | 1,334 | BP81RK8 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $6,666.40 | 520 | BTNMG41 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,642.02 | 2,497 | BKX9NQ0 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,226.56 | 752 | B9L5200 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $6,039.88 | 1,166 | BQ6C357 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,962.32 | 1,521 | BSMLR16 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,595.88 | 6,464 | BPG5P75 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,420.10 | 3,738 | BKMQF66 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $5,346.00 | 2,376 | BMW5LX6 |
| 0.01% | NKTX | NKARTA INC | -- | $4,915.15 | 2,495 | BK80YJ8 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,963.96 | 2,178 | BLBR8D5 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $3,880.33 | 4,029 | BCZS820 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,523.44 | 2,216 | BFDV8K0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,429.63 | 2,157 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,233.12 | 1,837 | BNLYBJ7 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,602.64 | 2,968 | BF12XC2 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,551.46 | 1,322 | BNKF6N0 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,182.80 | 856 | BMF1LJ7 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,093.33 | 4,977 | BJL38Z1 |
| -- | PEPG | PEPGEN INC | -- | $1,699.04 | 1,148 | BMTX3D7 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,673.52 | 1,101 | BP2TPK4 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,249.50 | 175 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,107.40 | 452 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $826.04 | 428 | BS2FKQ4 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,516,263 | -- | 3,675 | -- |
| 25.85% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 14,332,354 | -- | 3,007 | -- |
| 25.61% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 14,198,897 | -- | 2,979 | -- |
| 20.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 11,420,127 | -- | 2,396 | -- |
| 16.54% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,170,419 | -- | 1,924 | -- |
| 16.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,146,587 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,986,293.35 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $15,329,046.91 | 15,329,047 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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