BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $72,272,686
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/27/2026- NAV
- NAV Change
- Market Price $83.06
- Market Price Change $+0.54
- Trading Volume (M) 2,589
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $72,272,686
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/27/2026- NAV
- NAV Change
- Market Price $83.06
- Market Price Change $+0.54
- Trading Volume (M) 2,589
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/27/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.72% | GILD | GILEAD SCIENCES INC | -- | $3,414,709.98 | 25,542 | 2369174 |
| 4.63% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,347,793.54 | 7,657 | 2931034 |
| 4.56% | AMGN | AMGEN INC | -- | $3,294,396.18 | 9,803 | 2023607 |
| 3.34% | REGN | REGENERON PHARMACEUTICALS | -- | $2,410,521.60 | 3,840 | 2730190 |
| 2.01% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,449,769.52 | 4,904 | B00FWN1 |
| 1.55% | RVMD | REVOLUTION MEDICINES INC | -- | $1,120,878.00 | 7,326 | BL71K91 |
| 1.48% | BIIB | BIOGEN INC | -- | $1,068,562.25 | 5,425 | 2455965 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $924,615.00 | 1,620 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $861,661.50 | 1,050 | BDVLM39 |
| 1.18% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $854,722.89 | 15,837 | BMVP7Y0 |
| 1.17% | ILMN | ILLUMINA INC | -- | $848,911.01 | 5,653 | 2613990 |
| 1.17% | INSM | INSMED INC | -- | $847,795.20 | 7,968 | 2614487 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $782,686.80 | 26,460 | BMW4NZ9 |
| 0.99% | INCY | INCYTE CORP | -- | $716,325.06 | 7,359 | 2471950 |
| 0.96% | MRNA | MODERNA INC | -- | $695,106.00 | 14,600 | BGSXTS3 |
| 0.96% | VTRS | VIATRIS INC | -- | $693,383.85 | 42,565 | BMWS3X9 |
| 0.86% | GH | GUARDANT HEALTH INC | -- | $618,423.50 | 4,850 | BFXC911 |
| 0.80% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $578,440.96 | 3,712 | 2623911 |
| 0.75% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $540,449.00 | 2,275 | B4Q5ZN4 |
| 0.74% | ASND | ASCENDIS PHARMA A/S | -- | $535,451.76 | 2,276 | BWXJHM8 |
| 0.69% | SMMT | SUMMIT THERAPEUTICS INC | -- | $497,607.04 | 28,664 | BMTVQS7 |
| 0.66% | EXEL | EXELIXIS INC | -- | $480,288.00 | 9,600 | 2576941 |
| 0.66% | BBIO | BRIDGEBIO PHARMA INC | -- | $476,175.48 | 7,167 | BK1KWG8 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $467,277.41 | 6,109 | BDJ0LS6 |
| 0.62% | MEDP | MEDPACE HOLDINGS INC | -- | $449,828.00 | 1,051 | BDCBC61 |
| 0.62% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $446,936.49 | 847 | BD59BS7 |
| 0.61% | AXSM | AXSOME THERAPEUTICS INC | -- | $443,242.80 | 1,890 | BYZR4X4 |
| 0.57% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $409,010.22 | 5,178 | BYQBFJ8 |
| 0.56% | SNY | SANOFI-ADR | -- | $401,958.21 | 9,047 | 2964557 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $391,809.00 | 4,213 | BK6H543 |
| 0.52% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $372,421.80 | 7,110 | 2437071 |
| 0.51% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $367,486.77 | 1,029 | BQ721R4 |
| 0.49% | ONC | BEONE MEDICINES LTD-ADR | -- | $354,311.81 | 1,181 | BYYWPW6 |
| 0.49% | CYTK | CYTOKINETICS INC | -- | $351,263.95 | 4,553 | BBBSBJ5 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $331,160.40 | 1,080 | BD6JX35 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $303,020.08 | 6,424 | BSLSJJ0 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $299,883.12 | 38,008 | BNSP0B8 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $299,588.60 | 4,364 | 2975098 |
| 0.41% | ABVX | ABIVAX SA-ADR | -- | $294,616.83 | 2,271 | BLC89B2 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $290,462.90 | 2,705 | BMVBZD3 |
| 0.38% | PCVX | VAXCYTE INC | -- | $271,477.42 | 5,321 | BKPVGH6 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $251,343.43 | 7,523 | BJRFSB7 |
| 0.34% | KYMR | KYMERA THERAPEUTICS INC | -- | $246,488.90 | 3,017 | BMPRZV5 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $241,317.81 | 2,361 | BDCBCD8 |
| 0.32% | ALKS | ALKERMES PLC | -- | $234,748.67 | 6,163 | B3P6D26 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $230,926.92 | 2,526 | BF2YWG4 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $217,143.23 | 2,231 | BJDX8Y8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $216,360.92 | 3,062 | B17VCN9 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $210,641.55 | 2,905 | BQBBDY8 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $207,129.02 | 6,002 | BLR6XK8 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $191,064.72 | 3,773 | BFZQ0L8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $190,031.50 | 3,550 | BDHF4K6 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $189,878.40 | 3,123 | BRBCSP4 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,902.71 | 4,423 | BLB0YQ9 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $173,615.04 | 736 | 2501578 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,596.64 | 4,624 | BTZRLN8 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $165,688.60 | 3,074 | BRJ3GY4 |
| 0.23% | TVTX | TRAVERE THERAPEUTICS INC | -- | $162,813.84 | 3,409 | BLFGJD5 |
| 0.22% | CAI | CARIS LIFE SCIENCES INC | -- | $160,428.78 | 10,431 | BT18HP9 |
| 0.22% | APGE | APOGEE THERAPEUTICS INC | -- | $157,677.00 | 2,028 | BM9HHL5 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $155,453.12 | 4,252 | BP8JSP4 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $148,656.96 | 11,632 | BFNF1D6 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $145,409.22 | 2,266 | BGKG6G7 |
| 0.20% | ERAS | ERASCA INC | -- | $142,706.68 | 11,444 | BNLYBF3 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $142,450.88 | 3,872 | BDD19F8 |
| 0.18% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $133,560.57 | 6,303 | 2713317 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $133,019.64 | 3,966 | BKY5JZ8 |
| 0.18% | VCYT | VERACYTE INC | -- | $130,711.62 | 2,938 | BFTWZY0 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $120,129.63 | 3,767 | BK6L288 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $118,491.23 | 5,863 | BD2B4V0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $113,875.20 | 2,880 | BQS9486 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $110,994.01 | 4,351 | BKS3RS7 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $110,539.92 | 6,087 | BN15WD1 |
| 0.14% | ORKA | ORUKA THERAPEUTICS INC | -- | $103,744.11 | 1,789 | BKVF0J2 |
| 0.14% | GRAL | GRAIL INC | -- | $102,773.38 | 1,439 | BSLSSX7 |
| 0.14% | ALMS | ALUMIS INC | -- | $99,696.42 | 4,674 | BPLQG36 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $98,876.80 | 2,120 | B72ZBG4 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $98,431.36 | 1,411 | BMGJZJ8 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $97,817.70 | 4,978 | BP2P6L0 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $97,015.05 | 4,587 | BKX9VD3 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $95,324.58 | 6,606 | BN2R582 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $95,042.88 | 3,246 | BK0VHF6 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $94,474.38 | 1,573 | BMH5RL1 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $90,936.36 | 2,196 | BMFD115 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $90,335.72 | 2,636 | BL55460 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $88,977.00 | 3,122 | BMX9K07 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $88,024.32 | 1,698 | BRXB0C0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $87,779.25 | 2,925 | BP9N0G0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $86,671.20 | 3,685 | BV2DHY6 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $84,551.52 | 9,271 | 2100362 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $83,525.69 | 3,571 | BJ62Z18 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $79,127.95 | 2,255 | BFXC933 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $78,777.28 | 5,692 | BJ5FZ74 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $76,363.56 | 4,914 | BFWLC09 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $71,702.93 | 1,651 | BQKXDX4 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $71,510.91 | 4,209 | BYSS4X4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $69,755.49 | 2,367 | BMZ2X38 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $69,735.60 | 8,805 | B9NSBM2 |
| 0.10% | RAPP | RAPPORT THERAPEUTICS INC | -- | $69,695.64 | 1,764 | BR3T9B6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $68,738.46 | 8,049 | BNZB1X8 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $68,569.14 | 2,766 | BPCQZY9 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $68,521.90 | 4,742 | BJH9ZN0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,860.80 | 830 | BCDWBX6 |
| 0.09% | NVAX | NOVAVAX INC | -- | $66,795.07 | 6,023 | BJDQXG4 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,563.84 | 15,232 | BF0DMK7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $66,420.94 | 3,802 | BMVLGP2 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $66,390.95 | 2,111 | BJQ05Z6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,826.40 | 2,140 | BKSGZN7 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $65,477.58 | 1,974 | BMVNDH9 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $64,635.00 | 3,875 | B8DPDT7 |
| 0.09% | VCEL | VERICEL CORP | -- | $64,256.25 | 1,875 | BSBMN89 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $63,948.21 | 3,261 | BN7Q7R7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $63,543.09 | 2,379 | BBC9WC7 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $61,990.92 | 2,166 | BCBVTX1 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $61,171.49 | 19,297 | BM9FJ13 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $60,976.96 | 11,209 | BL53SR3 |
| 0.08% | INVA | INNOVIVA INC | -- | $60,636.20 | 2,740 | BDDXF67 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $59,016.87 | 1,023 | BDRW1L7 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $58,719.36 | 4,369 | BYZM6C2 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $58,236.00 | 10,128 | BNC1BX1 |
| 0.08% | QURE | UNIQURE NV | -- | $58,016.85 | 2,305 | BJFSR88 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $58,013.28 | 13,429 | BWJDYK1 |
| 0.08% | PGEN | PRECIGEN INC | -- | $57,552.00 | 13,080 | BKM5C84 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $57,110.13 | 4,059 | BPCK358 |
| 0.08% | ARDX | ARDELYX INC | -- | $55,937.22 | 9,066 | BN89V40 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,311.00 | 537 | BNSP8K3 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,021.06 | 2,818 | BP7KZP7 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $52,871.00 | 5,810 | BK4PZ38 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,857.04 | 1,658 | BQXJKH2 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $51,293.84 | 2,294 | BP6C0S2 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $50,740.90 | 1,730 | BZ7PJQ1 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $50,561.94 | 2,343 | BQB42F1 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,097.30 | 1,870 | BD06CS0 |
| 0.07% | SEPN | SEPTERNA INC | -- | $49,362.03 | 1,657 | BQNKXX2 |
| 0.07% | HROW | HARROW INC | -- | $47,169.10 | 1,370 | BHNDW86 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $46,366.10 | 3,455 | BRXYZ57 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $46,316.90 | 1,778 | BSRK699 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,230.92 | 1,621 | BLCD809 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $44,126.40 | 6,960 | BYZG9R0 |
| 0.06% | ALVO | ALVOTECH SA | -- | $42,002.40 | 12,210 | BPNTJ34 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $41,946.69 | 1,527 | BMGTLY5 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $41,320.95 | 3,487 | BMC3HS7 |
| 0.06% | MNKD | MANNKIND CORP | -- | $40,430.95 | 11,389 | BF081J4 |
| 0.06% | EYPT | EYEPOINT INC | -- | $40,295.92 | 3,062 | BMGS7L1 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $39,488.22 | 3,054 | BYP80F1 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,472.96 | 1,172 | BX7RSN3 |
| 0.05% | SVRA | SAVARA INC | -- | $39,200.04 | 7,524 | BYXGN81 |
| 0.05% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $38,239.42 | 2,962 | BMZ4LN0 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $38,214.82 | 6,134 | BLR7H87 |
| 0.05% | PSNL | PERSONALIS INC | -- | $36,716.81 | 3,869 | BJQ0608 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $36,305.50 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $35,939.80 | 1,495 | B3X26D8 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $35,872.47 | 1,983 | BQB42H3 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,911.20 | 2,185 | BM90J52 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,990.40 | 7,110 | BZ0QMB7 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $32,952.32 | 3,218 | BYZD465 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $32,504.44 | 2,251 | BMFX8Y7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,140.80 | 992 | BGL0JK3 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $32,030.70 | 1,677 | BNFWZS4 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,840.38 | 3,711 | BKVDFF7 |
| 0.04% | XNCR | XENCOR INC | -- | $31,772.92 | 2,711 | BGCYWN8 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $31,274.88 | 2,912 | BJLKVS6 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,076.00 | 3,656 | BMCR7V2 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,487.50 | 1,875 | BMNDK09 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $30,137.94 | 9,849 | BMFJJ97 |
| 0.04% | GERN | GERON CORP | -- | $29,738.52 | 23,602 | 2370381 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,422.75 | 2,975 | BFYQFJ2 |
| 0.04% | OMER | OMEROS CORP | -- | $29,025.54 | 2,622 | B4NB858 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,831.11 | 5,349 | BMVV9R5 |
| 0.04% | ABSI | ABSCI CORP | -- | $28,694.76 | 5,561 | BN94K69 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,352.44 | 1,934 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $27,187.80 | 1,604 | BT9K6D8 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,095.07 | 763 | BL95N25 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,627.06 | 2,911 | BJ0LT31 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $23,869.65 | 6,265 | BYWVTY5 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,838.72 | 1,536 | BRJJYT3 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $23,717.61 | 1,269 | BD9GVY0 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,641.70 | 5,410 | BMCWKZ2 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,386.00 | 1,100 | BKLCWZ3 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,365.50 | 2,105 | BMFK3H6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,808.85 | 2,083 | BLFBZ32 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,363.88 | 6,028 | B3MZ6K5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $22,020.90 | 6,673 | BPBJFM7 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,791.35 | 2,707 | BP0TQC5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,087.99 | 693 | BPBPCG8 |
| 0.03% | ARVN | ARVINAS INC | -- | $20,912.55 | 2,363 | BDZ30Q0 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,422.22 | 4,459 | BYV2W40 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $20,217.60 | 2,880 | BQHN6C7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $19,949.67 | 1,989 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,810.56 | 672 | BQD3J33 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $18,693.00 | 8,308 | BFZNYB7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,142.08 | 2,112 | BSMLR16 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,044.00 | 4,511 | BYVQJ96 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,993.34 | 2,349 | BP81R42 |
| 0.02% | KMDA | KAMADA LTD | -- | $17,029.32 | 2,134 | B2Q9833 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,705.92 | 2,464 | BJDX8Z9 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,682.25 | 1,885 | BKLXFX5 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,511.22 | 1,023 | BS2CR64 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,495.22 | 1,997 | BRCFFK6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,342.77 | 571 | BS2F741 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,196.04 | 548 | B292NQ7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,106.56 | 1,124 | BPRBTY7 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,813.46 | 2,397 | BDRJH21 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,400.27 | 11,163 | B4N8MH9 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $14,349.10 | 3,053 | BDDVW37 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,139.68 | 1,072 | B9L5200 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,129.28 | 4,014 | BMXNGZ6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $14,121.56 | 2,186 | B12W3P6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,800.38 | 4,631 | BFY7DC4 |
| 0.02% | OABI | OMNIAB INC | -- | $13,783.98 | 5,322 | BN13S71 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,735.49 | 1,879 | B7F2TY6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,727.73 | 2,697 | BQ6C357 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,623.31 | 3,557 | BK5MWR1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,497.66 | 3,609 | BKX9NQ0 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,166.51 | 787 | BTNMG41 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $13,144.95 | 2,889 | BLN9Z50 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,891.27 | 3,611 | BZ8FPH3 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $12,734.65 | 2,387 | BMVBZF5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,723.75 | 1,125 | BM7V485 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,530.37 | 1,873 | BZ0G875 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,515.58 | 2,646 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,455.52 | 7,414 | BFMLGR4 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,998.87 | 4,013 | BDFKQ07 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,804.80 | 1,736 | BL5B6Z1 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,575.72 | 10,244 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,487.36 | 6,176 | BN4JN37 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $10,902.53 | 3,721 | BZC0D70 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,455.76 | 3,426 | BYTYP72 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,388.08 | 1,416 | BP81RK8 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,244.55 | 2,165 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,171.50 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,951.34 | 1,158 | BQV0J03 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,820.24 | 3,341 | B5LL2C2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,563.47 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,281.34 | 1,147 | BP2NYN2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,251.55 | 2,089 | BPRB2N7 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,206.40 | 7,136 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,169.90 | 7,230 | BNR5QT9 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,058.32 | 1,052 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,978.74 | 3,454 | BNYJR68 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,924.00 | 1,981 | BP7L561 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,819.27 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,762.37 | 4,151 | BKRRKY7 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,685.34 | 1,387 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,346.31 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,924.88 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,862.55 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,984.19 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,862.32 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,427.60 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,207.96 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,864.13 | 8,555 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 32.62% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 23,576,957 | -- | 3,975 | -- |
| 28.92% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,901,936 | -- | 3,524 | -- |
| 27.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,012,240 | -- | 3,374 | -- |
| 21.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,652,727 | -- | 2,639 | -- |
| 20.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,905,382 | -- | 2,513 | -- |
| 5.20% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,754,519 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,290,263.64 | 21,290,264 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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