BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View fund details
Documents & Downloads
ETF & Index
Prospectus & Regulatory
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/12/2026- NAV $79.43
- NAV Change $-4.54
- Market Price $79.42
- Market Price Change $-4.55
- Trading Volume (M) 18,216
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/12/2026- NAV $79.43
- NAV Change $-4.54
- Market Price $79.42
- Market Price Change $-4.55
- Trading Volume (M) 18,216
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/11/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.61% | GILD | GILEAD SCIENCES INC | -- | $5,664,508.00 | 38,798 | 2369174 |
| 6.47% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,543,706.42 | 11,259 | 2931034 |
| 6.23% | AMGN | AMGEN INC | -- | $5,337,563.76 | 14,134 | 2023607 |
| 4.19% | REGN | REGENERON PHARMACEUTICALS | -- | $3,592,098.42 | 4,637 | 2730190 |
| 2.22% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,900,470.33 | 5,931 | B00FWN1 |
| 1.56% | INSM | INSMED INC | -- | $1,334,615.60 | 9,574 | 2614487 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,254,501.28 | 6,586 | 2455965 |
| 1.23% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,052,379.72 | 1,932 | 2430412 |
| 1.15% | MRNA | MODERNA INC | -- | $981,657.83 | 17,539 | BGSXTS3 |
| 1.11% | ARGX | ARGENX SE - ADR | -- | $950,885.54 | 1,306 | BDVLM39 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $923,605.92 | 31,224 | BMW4NZ9 |
| 1.05% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $895,654.27 | 19,183 | BMVP7Y0 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $864,341.61 | 8,679 | BL71K91 |
| 0.97% | INCY | INCYTE CORP | -- | $834,238.58 | 8,813 | 2471950 |
| 0.97% | ILMN | ILLUMINA INC | -- | $833,368.50 | 6,859 | 2613990 |
| 0.84% | VTRS | VIATRIS INC | -- | $722,374.73 | 51,709 | BMWS3X9 |
| 0.73% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $627,217.50 | 2,757 | BV9G6B8 |
| 0.72% | BBIO | BRIDGEBIO PHARMA INC | -- | $617,594.89 | 8,651 | BK1KWG8 |
| 0.71% | MEDP | MEDPACE HOLDINGS INC | -- | $604,315.80 | 1,265 | BDCBC61 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $579,821.04 | 4,476 | 2623911 |
| 0.63% | IONS | IONIS PHARMACEUTICALS INC | -- | $543,798.09 | 7,271 | BDJ0LS6 |
| 0.63% | SMMT | SUMMIT THERAPEUTICS INC | -- | $537,441.84 | 33,423 | BMTVQS7 |
| 0.61% | SNY | SANOFI-ADR | -- | $522,051.14 | 11,881 | 2964557 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $520,260.00 | 8,625 | 2437071 |
| 0.60% | GH | GUARDANT HEALTH INC | -- | $511,278.24 | 5,808 | BFXC911 |
| 0.59% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $505,853.04 | 2,728 | B4Q5ZN4 |
| 0.59% | EXEL | EXELIXIS INC | -- | $502,544.75 | 12,037 | 2576941 |
| 0.51% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $439,297.54 | 1,018 | BD59BS7 |
| 0.49% | ONC | BEONE MEDICINES LTD-ADR | -- | $422,658.74 | 1,414 | BYYWPW6 |
| 0.48% | BNTX | BIONTECH SE-ADR | -- | $412,322.76 | 4,539 | BK6H543 |
| 0.48% | TEM | ADD | -- | $408,796.80 | 7,760 | BSLSJJ0 |
| 0.43% | IBRX | IMMUNITYBIO INC | -- | $365,707.67 | 44,221 | BNSP0B8 |
| 0.42% | AXSM | AXSOME THERAPEUTICS INC | -- | $360,948.50 | 2,263 | BYZR4X4 |
| 0.41% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $354,235.70 | 6,097 | BYQBFJ8 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $351,014.40 | 5,280 | 2975098 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $349,328.70 | 5,490 | BBBSBJ5 |
| 0.39% | PCVX | VAXCYTE INC | -- | $338,046.28 | 5,876 | BKPVGH6 |
| 0.39% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $333,497.31 | 1,123 | BQ721R4 |
| 0.39% | KRYS | KRYSTAL BIOTECH INC | -- | $331,755.00 | 1,301 | BD6JX35 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $324,462.15 | 3,243 | BMVBZD3 |
| 0.35% | ABVX | ABIVAX SA-ADR | -- | $297,621.50 | 2,650 | BLC89B2 |
| 0.35% | ACLX | ARCELLX INC | -- | $296,878.56 | 2,596 | BPCJ1Q2 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $270,819.36 | 2,807 | BDCBCD8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $269,699.92 | 2,996 | BF2YWG4 |
| 0.31% | KYMR | KYMERA THERAPEUTICS INC | -- | $263,309.60 | 3,230 | BMPRZV5 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $248,663.36 | 6,892 | BLR6XK8 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $236,740.35 | 3,605 | B17VCN9 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $235,859.54 | 12,667 | BT18HP9 |
| 0.27% | CGON | CG ONCOLOGY INC | -- | $234,133.86 | 3,621 | BRBCSP4 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $213,600.54 | 4,278 | BDHF4K6 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $211,667.25 | 2,307 | BJDX8Y8 |
| 0.24% | ALKS | ALKERMES PLC | -- | $205,831.24 | 7,412 | B3P6D26 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $204,868.80 | 3,470 | BRJ3GY4 |
| 0.23% | IMVT | IMMUNOVANT INC | -- | $201,157.20 | 7,870 | BJRFSB7 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $199,067.61 | 13,853 | B19FQ48 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $197,764.40 | 4,580 | BFZQ0L8 |
| 0.23% | ERAS | ERASCA INC | -- | $197,423.50 | 12,737 | BNLYBF3 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $195,354.92 | 883 | 2501578 |
| 0.22% | TERN | TERNS PHARMACEUTICALS INC | -- | $189,178.32 | 4,044 | BMDJ0C9 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $183,946.49 | 5,603 | BTZRLN8 |
| 0.21% | APGE | APOGEE THERAPEUTICS INC | -- | $183,862.16 | 2,462 | BM9HHL5 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $179,388.94 | 14,114 | BFNF1D6 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $174,600.00 | 3,000 | BQS9486 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $167,449.62 | 10,686 | B9NSBM2 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $166,884.12 | 7,596 | 2713317 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $159,571.50 | 5,090 | BP8JSP4 |
| 0.18% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $157,534.80 | 4,260 | BDD19F8 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $147,295.47 | 4,753 | BKY5JZ8 |
| 0.17% | SYRE | SPYRE THERAPEUTICS INC | -- | $144,544.50 | 3,483 | BQBBDY8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $142,280.24 | 6,584 | BD2B4V0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $136,988.28 | 2,574 | B72ZBG4 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $134,020.80 | 3,936 | BK0VHF6 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $133,261.16 | 1,907 | BMH5RL1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $131,725.00 | 5,500 | BKX9VD3 |
| 0.15% | TWST | TWIST BIOSCIENCE CORP | -- | $128,630.70 | 2,745 | BGKG6G7 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $128,195.87 | 6,413 | BN15WD1 |
| 0.14% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $122,220.82 | 4,331 | BLB0YQ9 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $120,570.72 | 2,868 | BL55460 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $118,794.40 | 4,555 | BK6L288 |
| 0.13% | VCYT | VERACYTE INC | -- | $115,168.08 | 3,548 | BFTWZY0 |
| 0.13% | ALMS | ALUMIS INC | -- | $114,974.10 | 4,365 | BPLQG36 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $114,363.99 | 4,017 | BLFGJD5 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $110,020.26 | 5,677 | BYTQ6X1 |
| 0.13% | MAZE | MAZE THERAPEUTICS INC | -- | $108,950.40 | 2,160 | BSRK699 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $108,289.60 | 1,696 | BMGJZJ8 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $106,985.34 | 5,229 | BKS3RS7 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $105,726.72 | 7,509 | BYZG9R0 |
| 0.12% | TNGX | TANGO THERAPEUTICS INC | -- | $102,738.53 | 6,047 | BP2P6L0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $99,349.44 | 3,552 | BP9N0G0 |
| 0.11% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $97,941.25 | 4,609 | BLB0YH0 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $97,449.66 | 6,853 | BJ5FZ74 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $97,278.16 | 2,564 | BJQ05Z6 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $96,191.51 | 4,331 | BJ62Z18 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $95,364.88 | 3,902 | BN7Q7R7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $93,916.68 | 2,028 | BRXB0C0 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $90,867.50 | 9,565 | BNZB1X8 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $87,675.20 | 5,920 | BFWLC09 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $87,549.84 | 2,396 | BMVNDH9 |
| 0.10% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $86,258.48 | 17,822 | BF0DMK7 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $84,470.40 | 3,360 | BPCQZY9 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $84,034.80 | 7,781 | BN2R582 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $82,672.80 | 4,704 | B8DPDT7 |
| 0.10% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $82,381.86 | 4,422 | BV2DHY6 |
| 0.10% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $81,815.50 | 2,665 | BMFD115 |
| 0.09% | GRAL | GRAIL INC | -- | $81,077.50 | 1,750 | BSLSSX7 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $80,320.14 | 1,242 | BDRW1L7 |
| 0.09% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $80,247.48 | 9,452 | 2100362 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,643.25 | 23,085 | BM9FJ13 |
| 0.09% | PHVS | PHARVARIS NV | -- | $78,888.68 | 2,876 | BMZ2X38 |
| 0.09% | NVAX | NOVAVAX INC | -- | $78,796.80 | 7,296 | BJDQXG4 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,976.61 | 1,009 | BCDWBX6 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $76,875.14 | 2,003 | BQKXDX4 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $76,620.60 | 3,780 | BMX9K07 |
| 0.09% | INVA | INNOVIVA INC | -- | $75,263.94 | 3,357 | BDDXF67 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $74,807.34 | 2,174 | BKVF0J2 |
| 0.09% | VCEL | VERICEL CORP | -- | $74,670.48 | 2,271 | BSBMN89 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,450.94 | 2,586 | BKSGZN7 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $73,619.83 | 4,931 | BPCK358 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $73,487.26 | 2,618 | BCBVTX1 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $72,572.50 | 4,550 | BMVLGP2 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $71,872.50 | 2,625 | BBC9WC7 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $68,738.58 | 5,757 | BJH9ZN0 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $67,652.00 | 5,200 | BYZM6C2 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $66,202.36 | 16,306 | BWJDYK1 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,338.92 | 10,908 | BN89V40 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,325.06 | 2,139 | BR3T9B6 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $63,706.68 | 1,959 | BLCD809 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $63,440.74 | 5,027 | BYSS4X4 |
| 0.07% | HROW | HARROW INC | -- | $61,394.28 | 1,662 | BHNDW86 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $61,335.72 | 6,246 | BK4PZ38 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $61,069.40 | 2,410 | BQB42H3 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $58,454.28 | 2,382 | BFXC933 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $58,314.10 | 2,015 | BQXJKH2 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $56,665.70 | 3,353 | BYP80F1 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,525.47 | 12,298 | BNC1BX1 |
| 0.06% | EYPT | EYEPOINT INC | -- | $55,442.72 | 3,716 | BMGS7L1 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $55,134.52 | 3,532 | BMZ4LN0 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $55,056.07 | 4,373 | BKVDFF7 |
| 0.06% | PGEN | PRECIGEN INC | -- | $54,330.12 | 15,886 | BKM5C84 |
| 0.06% | SEPN | SEPTERNA INC | -- | $52,856.79 | 2,009 | BQNKXX2 |
| 0.06% | ALVO | ALVOTECH SA | -- | $52,421.42 | 14,054 | BPNTJ34 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $50,580.40 | 1,420 | BX7RSN3 |
| 0.06% | SVRA | SAVARA INC | -- | $50,516.55 | 9,135 | BYXGN81 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $49,866.38 | 2,923 | BP7KZP7 |
| 0.06% | QURE | UNIQURE NV | -- | $49,115.32 | 2,797 | BJFSR88 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $49,048.70 | 13,438 | BL53SR3 |
| 0.06% | BCAX | BICARA THERAPEUTICS INC | -- | $48,954.00 | 2,460 | BQB42F1 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $48,069.00 | 654 | BNSP8K3 |
| 0.06% | GERN | GERON CORP | -- | $47,572.28 | 28,658 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $46,064.40 | 920 | BL95N25 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,626.94 | 1,854 | BMGTLY5 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,061.90 | 1,930 | B3X26D8 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $43,980.31 | 5,477 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,688.50 | 7,450 | BLR7H87 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $42,121.92 | 2,784 | BP6C0S2 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $41,404.80 | 2,270 | BD06CS0 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $40,757.20 | 8,635 | BZ0QMB7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $39,601.68 | 2,102 | BZ7PJQ1 |
| 0.05% | ANNX | ANNEXON INC | -- | $39,176.91 | 6,497 | BMVV9R5 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,074.16 | 4,148 | BRXYZ57 |
| 0.05% | MNKD | MANNKIND CORP | -- | $38,876.52 | 13,786 | BF081J4 |
| 0.05% | ARVN | ARVINAS INC | -- | $38,862.84 | 2,883 | BDZ30Q0 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $38,741.28 | 2,064 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $38,600.24 | 3,206 | BGCYWN8 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $38,030.08 | 2,701 | BMFX8Y7 |
| 0.04% | OMER | OMEROS CORP | -- | $37,985.12 | 3,184 | B4NB858 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,950.12 | 2,652 | BM90J52 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,674.00 | 11,960 | BMFJJ97 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $37,190.44 | 4,438 | BMCR7V2 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $37,122.16 | 7,607 | BYWVTY5 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $36,013.32 | 3,906 | BYZD465 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $35,585.99 | 3,193 | BJLKVS6 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,417.26 | 2,202 | BQS7491 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $34,230.30 | 1,310 | BKLCWZ3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $33,525.06 | 1,758 | BD9GVY0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,312.70 | 1,610 | BT9K6D8 |
| 0.04% | PSNL | PERSONALIS INC | -- | $31,696.65 | 3,987 | BJQ0608 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $31,431.56 | 2,276 | BMNDK09 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $31,034.49 | 8,103 | BPBJFM7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $29,223.60 | 840 | BPBPCG8 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $29,151.59 | 4,231 | BMC3HS7 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,217.53 | 3,613 | BFYQFJ2 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $27,823.80 | 3,522 | BDDVW37 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,795.88 | 10,732 | BBNBTD2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,987.07 | 3,498 | BQHN6C7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,878.72 | 7,304 | B3MZ6K5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $26,534.07 | 10,089 | BFZNYB7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,316.48 | 2,528 | BLFBZ32 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,605.58 | 2,558 | BMFK3H6 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $25,315.88 | 7,501 | BN4JN37 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $24,646.37 | 2,653 | B12W3P6 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $24,065.92 | 4,852 | BDFKQ07 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $23,908.14 | 951 | BTNMG41 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,669.22 | 3,538 | BJ0LT31 |
| 0.03% | IVVD | INVIVYD INC | -- | $23,639.80 | 12,442 | BM8NHS1 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $23,386.79 | 5,477 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $23,179.50 | 1,717 | BP81RK8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,154.86 | 2,417 | B91XRN2 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,110.50 | 6,510 | BMCWKZ2 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $22,698.00 | 2,425 | BRCFFK6 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $22,440.60 | 3,276 | BQ6C357 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,181.50 | 814 | BQD3J33 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,144.50 | 2,590 | B2Q9833 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,896.56 | 2,564 | BKLXFX5 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $21,798.45 | 1,205 | BGL0JK3 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $21,392.70 | 3,507 | BLN9Z50 |
| 0.02% | RGNX | REGENXBIO INC | -- | $21,320.74 | 2,273 | BZ0G875 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $21,190.00 | 650 | B292NQ7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $20,829.06 | 3,843 | BMXNGZ6 |
| 0.02% | PEPG | PEPGEN INC | -- | $19,417.23 | 3,087 | BMTX3D7 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,921.91 | 2,429 | BJDX8Z9 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $18,651.15 | 4,011 | BYTYP72 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,364.32 | 1,296 | B9L5200 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,299.25 | 13,555 | B4N8MH9 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,803.00 | 4,685 | BFY7DC4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $17,602.13 | 3,215 | 2107437 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $17,514.00 | 4,865 | BYV2W40 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,289.93 | 1,967 | BSMLR16 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $16,888.10 | 1,405 | BQV0J03 |
| 0.02% | ABSI | ABSCI CORP | -- | $16,542.40 | 6,752 | BN94K69 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $16,379.35 | 2,899 | BMVBZF5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,159.50 | 2,850 | BP81R42 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,005.85 | 695 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,690.29 | 2,911 | BDRJH21 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,534.26 | 1,037 | BPRBTY7 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,417.36 | 1,368 | BM7V485 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $15,027.74 | 4,667 | BKRRKY7 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,720.82 | 2,109 | BL5B6Z1 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,345.35 | 2,539 | BMF7DT9 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,129.67 | 4,321 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $14,049.36 | 9,006 | BFMLGR4 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,794.48 | 4,508 | BZC0D70 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,572.00 | 2,262 | B7F2TY6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,009.49 | 4,351 | BKX9NQ0 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $12,828.25 | 2,645 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $12,635.17 | 6,463 | BN13S71 |
| 0.01% | CADL | CANDEL THERAPEUTICS INC | -- | $12,571.50 | 2,465 | BP0TQC5 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,661.44 | 4,384 | BZ8FPH3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,661.00 | 2,535 | BPRB2N7 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $11,454.42 | 1,682 | 2517058 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $11,249.28 | 756 | BRJJYT3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,899.00 | 2,076 | BKDQKM6 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,004.33 | 8,407 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,660.06 | 5,427 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,518.96 | 1,276 | BKC9SX3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $9,219.00 | 8,780 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,266.12 | 4,196 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,990.08 | 1,392 | BP2NYN2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,610.99 | 3,413 | BPTK6Z2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,512.13 | 2,403 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,417.92 | 7,474 | BNNXX52 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,000.60 | 4,380 | BNNXX18 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,757.75 | 2,559 | BKTV702 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,149.85 | 4,055 | B5LL2C2 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $5,092.63 | 10,391 | BJ0CK86 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,080.40 | 977 | BTXQTX3 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,360.20 | 2,795 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $24.54 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.93% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,772,779 | -- | 5,211 | -- |
| 29.58% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,339,857 | -- | 4,291 | -- |
| 26.38% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,593,869 | -- | 3,826 | -- |
| 18.19% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,584,219 | -- | 2,639 | -- |
| 17.13% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,668,889 | -- | 2,484 | -- |
| 4.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,738,087 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,961,781.07 | 26,961,781 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More