BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/11/2026- NAV $84.92
- NAV Change $+0.72
- Market Price $84.87
- Market Price Change $+0.75
- Trading Volume (M) 6,255
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/11/2026- NAV $84.92
- NAV Change $+0.72
- Market Price $84.87
- Market Price Change $+0.75
- Trading Volume (M) 6,255
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/11/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 7.07% | GILD | GILEAD SCIENCES INC | -- | $6,304,135.40 | 40,463 | 2369174 |
| 6.07% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,416,341.32 | 11,743 | 2931034 |
| 6.06% | AMGN | AMGEN INC | -- | $5,403,022.62 | 14,739 | 2023607 |
| 4.22% | REGN | REGENERON PHARMACEUTICALS | -- | $3,767,098.92 | 4,836 | 2730190 |
| 2.24% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,993,624.08 | 6,186 | B00FWN1 |
| 1.66% | INSM | INSMED INC | -- | $1,482,221.98 | 9,986 | 2614487 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,313,352.80 | 6,869 | 2455965 |
| 1.28% | ARGX | ARGENX SE - ADR | -- | $1,137,491.65 | 1,363 | BDVLM39 |
| 1.08% | UTHR | UNITED THERAPEUTICS CORP | -- | $959,313.60 | 2,016 | 2430412 |
| 1.02% | INCY | INCYTE CORP | -- | $908,537.28 | 9,192 | 2471950 |
| 0.99% | RVMD | REVOLUTION MEDICINES INC | -- | $887,005.48 | 9,052 | BL71K91 |
| 0.99% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $885,221.25 | 20,005 | BMVP7Y0 |
| 0.98% | ROIV | ROIVANT SCIENCES LTD | -- | $872,715.20 | 32,564 | BMW4NZ9 |
| 0.98% | VTRS | VIATRIS INC | -- | $869,858.64 | 53,928 | BMWS3X9 |
| 0.93% | ILMN | ILLUMINA INC | -- | $832,582.52 | 7,154 | 2613990 |
| 0.83% | MRNA | MODERNA INC | -- | $741,008.92 | 18,292 | BGSXTS3 |
| 0.74% | BBIO | BRIDGEBIO PHARMA INC | -- | $661,583.26 | 9,022 | BK1KWG8 |
| 0.73% | GH | GUARDANT HEALTH INC | -- | $651,719.64 | 6,058 | BFXC911 |
| 0.72% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $641,569.92 | 4,668 | 2623911 |
| 0.72% | IONS | IONIS PHARMACEUTICALS INC | -- | $639,710.40 | 7,584 | BDJ0LS6 |
| 0.71% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $636,783.75 | 2,875 | BV9G6B8 |
| 0.68% | SNY | SANOFI-ADR | -- | $610,207.50 | 12,390 | 2964557 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $559,163.67 | 1,319 | BDCBC61 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $542,488.45 | 8,995 | 2437071 |
| 0.60% | EXEL | EXELIXIS INC | -- | $539,068.76 | 12,554 | 2576941 |
| 0.60% | SMMT | SUMMIT THERAPEUTICS INC | -- | $531,554.00 | 34,856 | BMTVQS7 |
| 0.58% | BNTX | BIONTECH SE-ADR | -- | $517,804.92 | 4,734 | BK6H543 |
| 0.58% | ONC | BEONE MEDICINES LTD-ADR | -- | $517,771.98 | 1,474 | BYYWPW6 |
| 0.58% | RNA | AVIDITY BIOSCIENCES INC | -- | $514,450.60 | 7,055 | BMWHPY1 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $511,303.00 | 1,063 | BD59BS7 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $472,952.80 | 2,845 | B4Q5ZN4 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $439,455.60 | 2,360 | BYZR4X4 |
| 0.49% | HALO | HALOZYME THERAPEUTICS INC | -- | $437,782.06 | 5,506 | 2975098 |
| 0.49% | TEM | TEMPUS AI INC | -- | $433,919.34 | 8,094 | BSLSJJ0 |
| 0.44% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $391,396.45 | 6,359 | BYQBFJ8 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $382,430.00 | 5,725 | BBBSBJ5 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $378,572.59 | 1,171 | BQ721R4 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $370,258.70 | 1,358 | BD6JX35 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $348,853.30 | 3,382 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $339,336.28 | 2,764 | BLC89B2 |
| 0.38% | PCVX | VAXCYTE INC | -- | $339,240.15 | 6,129 | BKPVGH6 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $307,718.75 | 3,125 | BF2YWG4 |
| 0.34% | IBRX | IMMUNITYBIO INC | -- | $301,611.72 | 46,118 | BNSP0B8 |
| 0.32% | CAI | CARIS LIFE SCIENCES INC | -- | $284,036.50 | 13,211 | BT18HP9 |
| 0.31% | KYMR | KYMERA THERAPEUTICS INC | -- | $277,167.63 | 3,369 | BMPRZV5 |
| 0.30% | ALKS | ALKERMES PLC | -- | $269,889.21 | 7,731 | B3P6D26 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $267,356.40 | 7,187 | BLR6XK8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $266,588.28 | 3,759 | B17VCN9 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $244,375.23 | 2,927 | BDCBCD8 |
| 0.27% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $240,311.28 | 2,406 | BJDX8Y8 |
| 0.27% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $237,741.42 | 3,129 | BQS9486 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $225,140.64 | 4,776 | BFZQ0L8 |
| 0.24% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $216,369.30 | 14,719 | BFNF1D6 |
| 0.24% | CRSP | CRISPR THERAPEUTICS AG | -- | $215,603.84 | 4,462 | BDHF4K6 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $212,889.58 | 8,207 | BJRFSB7 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $211,531.23 | 4,443 | BDD19F8 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $206,722.26 | 14,446 | B19FQ48 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $202,258.35 | 3,777 | BRBCSP4 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $199,163.52 | 5,844 | BTZRLN8 |
| 0.21% | ACLX | ARCELLX INC | -- | $189,165.16 | 2,707 | BPCJ1Q2 |
| 0.21% | GRAL | GRAIL INC | -- | $183,230.00 | 1,825 | BSLSSX7 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $181,780.16 | 5,309 | BP8JSP4 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $181,424.32 | 11,144 | B9NSBM2 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $177,984.87 | 7,921 | 2713317 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $171,455.12 | 922 | 2501578 |
| 0.19% | APGE | APOGEE THERAPEUTICS INC | -- | $168,934.27 | 2,567 | BM9HHL5 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $162,983.52 | 4,218 | BMDJ0C9 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $154,705.68 | 3,618 | BRJ3GY4 |
| 0.17% | ERAS | ERASCA INC | -- | $153,563.04 | 13,284 | BNLYBF3 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $152,493.65 | 5,735 | BKX9VD3 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $151,981.62 | 4,957 | BKY5JZ8 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $142,119.32 | 2,863 | BGKG6G7 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $137,847.90 | 2,685 | B72ZBG4 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $135,211.23 | 6,867 | BD2B4V0 |
| 0.15% | VCYT | VERACYTE INC | -- | $133,198.99 | 3,701 | BFTWZY0 |
| 0.15% | APLS | APELLIS PHARMACEUTICALS INC | -- | $132,097.51 | 5,921 | BYTQ6X1 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $130,949.50 | 4,105 | BK0VHF6 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $129,995.32 | 1,988 | BMH5RL1 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $128,493.36 | 2,991 | BL55460 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $127,278.32 | 1,768 | BMGJZJ8 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $126,591.58 | 4,189 | BLFGJD5 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $123,478.49 | 4,751 | BK6L288 |
| 0.14% | SYRE | SPYRE THERAPEUTICS INC | -- | $123,231.36 | 3,633 | BQBBDY8 |
| 0.13% | ALMS | ALUMIS INC | -- | $116,667.76 | 4,552 | BPLQG36 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $111,651.76 | 7,148 | BJ5FZ74 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $111,539.16 | 6,687 | BN15WD1 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $110,334.90 | 3,705 | BP9N0G0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $107,865.96 | 4,517 | BJ62Z18 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $106,420.52 | 4,517 | BLB0YQ9 |
| 0.12% | MAZE | MAZE THERAPEUTICS INC | -- | $106,386.66 | 2,253 | BSRK699 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $104,444.10 | 5,454 | BKS3RS7 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $103,917.37 | 7,831 | BYZG9R0 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $98,683.23 | 2,697 | BKSGZN7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $95,132.70 | 2,115 | BRXB0C0 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $91,371.00 | 9,975 | BNZB1X8 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,570.23 | 6,173 | BFWLC09 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $89,318.25 | 24,075 | BM9FJ13 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $88,359.70 | 4,070 | BN7Q7R7 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $88,111.76 | 4,906 | B8DPDT7 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $87,102.95 | 3,683 | BMZ4LN0 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $86,188.50 | 2,675 | BJQ05Z6 |
| 0.09% | HROW | HARROW INC | -- | $84,376.44 | 1,734 | BHNDW86 |
| 0.09% | ARDX | ARDELYX INC | -- | $82,597.02 | 11,377 | BN89V40 |
| 0.09% | MNKD | MANNKIND CORP | -- | $82,529.72 | 14,378 | BF081J4 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $82,274.22 | 2,737 | BBC9WC7 |
| 0.09% | VCEL | VERICEL CORP | -- | $82,003.84 | 2,368 | BSBMN89 |
| 0.09% | PHVS | PHARVARIS NV | -- | $81,902.69 | 2,999 | BMZ2X38 |
| 0.09% | PGEN | PRECIGEN INC | -- | $81,343.97 | 16,567 | BKM5C84 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $80,215.00 | 1,052 | BCDWBX6 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $80,018.20 | 4,612 | BV2DHY6 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $79,996.32 | 3,504 | BPCQZY9 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $79,518.66 | 6,306 | BP2P6L0 |
| 0.09% | INVA | INNOVIVA INC | -- | $78,702.48 | 3,501 | BDDXF67 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $77,839.79 | 2,779 | BMFD115 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $76,458.06 | 4,746 | BMVLGP2 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $76,347.70 | 2,090 | BQKXDX4 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $75,648.30 | 2,730 | BCBVTX1 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $74,970.00 | 2,499 | BMVNDH9 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,862.84 | 1,297 | BTJZB49 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $74,252.25 | 8,115 | BN2R582 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $73,787.70 | 5,142 | BPCK358 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $73,570.00 | 2,102 | BQXJKH2 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $73,084.68 | 3,942 | BMX9K07 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,020.07 | 2,267 | BKVF0J2 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $71,604.00 | 1,296 | BDRW1L7 |
| 0.08% | ALVO | ALVOTECH SA | -- | $71,081.60 | 14,656 | BPNTJ34 |
| 0.08% | QURE | UNIQURE NV | -- | $70,328.87 | 2,917 | BJFSR88 |
| 0.08% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $69,030.78 | 3,497 | BYP80F1 |
| 0.08% | NVAX | NOVAVAX INC | -- | $68,252.73 | 7,609 | BJDQXG4 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $67,509.85 | 17,005 | BWJDYK1 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $67,428.72 | 9,858 | 2100362 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $67,275.99 | 2,043 | BLCD809 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,807.20 | 1,480 | BX7RSN3 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $66,344.20 | 6,004 | BJH9ZN0 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,076.00 | 5,423 | BYZM6C2 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $61,692.48 | 2,232 | BR3T9B6 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $61,525.68 | 2,152 | BNFWZS4 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,764.50 | 12,825 | BNC1BX1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $58,477.51 | 2,513 | BQB42H3 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $57,809.04 | 3,049 | BP7KZP7 |
| 0.06% | KOD | KODIAK SCIENCES INC | -- | $56,908.44 | 2,484 | BFXC933 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,835.19 | 681 | BNSP8K3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $55,208.64 | 2,096 | BQNKXX2 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $55,051.50 | 5,243 | BYSS4X4 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $53,982.61 | 4,807 | BLB0YH0 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $53,683.79 | 7,769 | BLR7H87 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $52,607.52 | 5,712 | B8K7T65 |
| 0.06% | SVRA | SAVARA INC | -- | $50,969.45 | 9,527 | BYXGN81 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $50,138.34 | 4,326 | BRXYZ57 |
| 0.06% | EYPT | EYEPOINT INC | -- | $49,806.60 | 3,876 | BMGS7L1 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,407.68 | 959 | BL95N25 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $48,391.36 | 12,472 | BMFJJ97 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $48,333.88 | 6,514 | BK4PZ38 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $48,326.20 | 18,587 | BF0DMK7 |
| 0.05% | GERN | GERON CORP | -- | $48,121.29 | 29,889 | 2370381 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,573.54 | 3,341 | BMG99Y1 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $46,512.00 | 4,560 | BKVDFF7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $46,338.88 | 2,192 | BZ7PJQ1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,297.23 | 2,373 | BMNDK09 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $44,208.78 | 1,367 | BKLCWZ3 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $44,107.48 | 7,933 | BYWVTY5 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $43,995.60 | 2,904 | BP6C0S2 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $43,966.00 | 4,628 | BMCR7V2 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $43,866.95 | 14,015 | BL53SR3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,764.22 | 2,014 | B3X26D8 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $42,016.80 | 2,296 | BQS7491 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $41,791.46 | 1,933 | BMGTLY5 |
| 0.05% | XNCR | XENCOR INC | -- | $40,863.68 | 3,344 | BGCYWN8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,738.13 | 3,331 | BJLKVS6 |
| 0.04% | ARVN | ARVINAS INC | -- | $39,361.63 | 3,007 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $38,727.78 | 11,193 | BBNBTD2 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $37,962.00 | 2,565 | BQB42F1 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,460.80 | 9,005 | BZ0QMB7 |
| 0.04% | OMER | OMEROS CORP | -- | $37,283.60 | 3,320 | B4NB858 |
| 0.04% | UPB | UPSTREAM BIO INC | -- | $37,165.70 | 2,530 | BRCFFK6 |
| 0.04% | PSNL | PERSONALIS INC | -- | $37,006.20 | 4,158 | BJQ0608 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $36,917.76 | 2,816 | BMFX8Y7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $36,712.17 | 2,367 | BD06CS0 |
| 0.04% | ANNX | ANNEXON INC | -- | $35,511.48 | 6,777 | BMVV9R5 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $34,881.99 | 1,833 | BD9GVY0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $33,819.48 | 7,617 | B3MZ6K5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,563.21 | 1,679 | BT9K6D8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,081.36 | 2,766 | BM90J52 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,940.16 | 4,074 | BYZD465 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $29,699.00 | 850 | BQD3J33 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $29,159.40 | 8,452 | BPBJFM7 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $28,502.48 | 3,673 | BDDVW37 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,116.74 | 3,769 | BFYQFJ2 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $27,839.72 | 4,412 | BMC3HS7 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,630.12 | 2,667 | BMFK3H6 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $27,544.58 | 2,534 | BJDX8Z9 |
| 0.03% | CRMD | CORMEDIX INC | -- | $27,409.27 | 3,689 | BJ0LT31 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $26,010.24 | 14,136 | B4N8MH9 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $25,466.95 | 10,837 | BJ0CK86 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $24,743.75 | 2,675 | BKLXFX5 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $24,299.04 | 1,426 | BM7V485 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $24,169.62 | 993 | BTNMG41 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $23,469.00 | 7,823 | BN4JN37 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,347.20 | 3,648 | BQHN6C7 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $23,201.43 | 3,417 | BQ6C357 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $23,055.24 | 677 | B292NQ7 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,985.51 | 2,701 | B2Q9833 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $22,622.18 | 4,886 | BFY7DC4 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,503.60 | 2,520 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,353.28 | 2,636 | BLFBZ32 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,263.92 | 3,353 | 2107437 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,819.84 | 5,712 | BYVQJ96 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,184.80 | 6,790 | BMCWKZ2 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,889.75 | 12,975 | BM8NHS1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $20,558.81 | 2,767 | B12W3P6 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $20,158.80 | 1,256 | BGL0JK3 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,145.00 | 2,370 | BZ0G875 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,815.30 | 1,790 | BP81RK8 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $19,792.15 | 1,465 | BQV0J03 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,280.76 | 876 | BPBPCG8 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $19,251.75 | 1,351 | B9L5200 |
| 0.02% | PEPG | PEPGEN INC | -- | $18,444.87 | 3,219 | BMTX3D7 |
| 0.02% | ABSI | ABSCI CORP | -- | $18,306.60 | 7,041 | BN94K69 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,361.30 | 10,522 | BFZNYB7 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $17,197.47 | 5,073 | BYV2W40 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,708.26 | 2,973 | BP81R42 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,511.32 | 1,082 | BPRBTY7 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $16,502.52 | 4,868 | BKRRKY7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,394.40 | 5,060 | BDFKQ07 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $16,314.68 | 3,658 | BLN9Z50 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,230.04 | 4,183 | BYTYP72 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,663.76 | 2,359 | B7F2TY6 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $15,485.05 | 2,051 | BSMLR16 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,266.15 | 3,023 | BMVBZF5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,352.16 | 2,648 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,244.03 | 4,701 | BZC0D70 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $14,212.10 | 2,570 | BP0TQC5 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,430.56 | 9,392 | BFMLGR4 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,386.72 | 4,008 | BMXNGZ6 |
| 0.01% | EOLS | EVOLUS INC | -- | $13,050.50 | 3,035 | BDRJH21 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,910.73 | 1,019 | BTXQTX3 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,681.42 | 1,754 | 2517058 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,245.25 | 725 | BS2F741 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,999.64 | 2,166 | BKDQKM6 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $11,582.99 | 4,507 | BK5MWR1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,544.36 | 5,659 | BRK0149 |
| 0.01% | OABI | OMNIAB INC | -- | $11,458.00 | 6,740 | BN13S71 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,734.64 | 2,644 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,525.26 | 789 | BRJJYT3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,070.35 | 2,759 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,842.00 | 1,330 | BKC9SX3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $9,522.24 | 9,156 | BNR5QT9 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,521.67 | 2,199 | BL5B6Z1 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,855.68 | 8,768 | BMYTJP4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,304.54 | 4,538 | BKX9NQ0 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,090.67 | 4,571 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,623.00 | 1,452 | BP2NYN2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,957.84 | 4,376 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,922.96 | 2,668 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,891.43 | 4,567 | BNNXX18 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,298.94 | 7,796 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,287.66 | 2,506 | BP7L561 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,197.60 | 3,560 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,032.51 | 4,229 | B5LL2C2 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,935.25 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $15.73 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 39.98% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 35,646,119 | -- | 6,018 | -- |
| 29.33% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,151,149 | -- | 4,415 | -- |
| 22.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,500,368 | -- | 3,461 | -- |
| 17.53% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,631,457 | -- | 2,639 | -- |
| 16.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,713,353 | -- | 2,484 | -- |
| 4.20% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,749,417 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $27,143,730.90 | 27,143,731 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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