BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/26/2026- NAV $86.67
- NAV Change $-1.26
- Market Price $86.65
- Market Price Change $-1.28
- Trading Volume (M) 7,605
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/26/2026- NAV $86.67
- NAV Change $-1.26
- Market Price $86.65
- Market Price Change $-1.28
- Trading Volume (M) 7,605
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/25/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.42% | GILD | GILEAD SCIENCES INC | -- | $5,870,676.48 | 39,904 | 2369174 |
| 6.12% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,594,202.05 | 11,581 | 2931034 |
| 6.11% | AMGN | AMGEN INC | -- | $5,586,620.88 | 14,536 | 2023607 |
| 4.09% | REGN | REGENERON PHARMACEUTICALS | -- | $3,740,231.32 | 4,769 | 2730190 |
| 2.18% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,997,223.36 | 6,101 | B00FWN1 |
| 1.60% | INSM | INSMED INC | -- | $1,463,511.28 | 9,848 | 2614487 |
| 1.41% | BIIB | BIOGEN INC | -- | $1,292,005.02 | 6,774 | 2455965 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $1,097,980.80 | 1,344 | BDVLM39 |
| 1.16% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,063,778.80 | 1,988 | 2430412 |
| 1.01% | MRNA | MODERNA INC | -- | $926,663.43 | 18,039 | BGSXTS3 |
| 1.01% | RVMD | REVOLUTION MEDICINES INC | -- | $921,623.48 | 8,927 | BL71K91 |
| 1.01% | ROIV | ROIVANT SCIENCES LTD | -- | $920,387.24 | 32,114 | BMW4NZ9 |
| 0.99% | INCY | INCYTE CORP | -- | $906,318.70 | 9,065 | 2471950 |
| 0.97% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $890,764.35 | 19,729 | BMVP7Y0 |
| 0.94% | ILMN | ILLUMINA INC | -- | $859,792.85 | 7,055 | 2613990 |
| 0.94% | VTRS | VIATRIS INC | -- | $855,182.64 | 53,183 | BMWS3X9 |
| 0.71% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $646,380.00 | 2,835 | BV9G6B8 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $605,275.47 | 7,479 | BDJ0LS6 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $603,814.60 | 4,604 | 2623911 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $592,006.38 | 8,897 | BK1KWG8 |
| 0.64% | SNY | SANOFI-ADR | -- | $581,502.21 | 12,219 | 2964557 |
| 0.62% | MEDP | MEDPACE HOLDINGS INC | -- | $569,942.08 | 1,301 | BDCBC61 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $569,142.98 | 5,974 | BFXC911 |
| 0.61% | EXEL | EXELIXIS INC | -- | $554,049.75 | 12,381 | 2576941 |
| 0.60% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $552,304.98 | 2,806 | B4Q5ZN4 |
| 0.60% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $545,034.24 | 8,871 | 2437071 |
| 0.59% | SMMT | SUMMIT THERAPEUTICS INC | -- | $539,000.00 | 34,375 | BMTVQS7 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $512,842.96 | 4,669 | BK6H543 |
| 0.56% | ONC | BEONE MEDICINES LTD-ADR | -- | $512,142.42 | 1,454 | BYYWPW6 |
| 0.55% | RNAM | AVIDITY BIOSCIENCES INC | -- | $506,542.40 | 6,958 | BMWHPY1 |
| 0.50% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $455,890.48 | 1,048 | BD59BS7 |
| 0.47% | IBRX | IMMUNITYBIO INC | -- | $433,888.74 | 45,481 | BNSP0B8 |
| 0.47% | TEM | TEMPUS AI INC-CL A | -- | $428,713.22 | 7,982 | BSLSJJ0 |
| 0.44% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $401,420.25 | 1,155 | BQ721R4 |
| 0.42% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $386,387.67 | 6,271 | BYQBFJ8 |
| 0.42% | AXSM | AXSOME THERAPEUTICS INC | -- | $382,139.94 | 2,327 | BYZR4X4 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $382,000.50 | 5,430 | 2975098 |
| 0.42% | PCVX | VAXCYTE INC | -- | $381,013.76 | 6,044 | BKPVGH6 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $364,877.50 | 1,339 | BD6JX35 |
| 0.39% | CYTK | CYTOKINETICS INC | -- | $355,076.94 | 5,646 | BBBSBJ5 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $348,607.55 | 3,335 | BMVBZD3 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $336,197.58 | 2,726 | BLC89B2 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $305,580.30 | 3,082 | BF2YWG4 |
| 0.33% | ACLX | ARCELLX INC | -- | $303,739.20 | 2,670 | BPCJ1Q2 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $301,238.96 | 3,322 | BMPRZV5 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $283,307.36 | 7,088 | BLR6XK8 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $257,755.26 | 2,373 | BJDX8Y8 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $251,457.70 | 2,887 | BDCBCD8 |
| 0.27% | PTCT | PTC THERAPEUTICS INC | -- | $251,186.32 | 3,707 | B17VCN9 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $242,880.00 | 4,400 | BDHF4K6 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $238,560.99 | 13,029 | BT18HP9 |
| 0.26% | ALKS | ALKERMES PLC | -- | $236,648.96 | 7,624 | B3P6D26 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $221,228.70 | 4,710 | BFZQ0L8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $220,399.62 | 8,094 | BJRFSB7 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $212,287.75 | 3,725 | BRBCSP4 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $211,643.28 | 14,516 | BFNF1D6 |
| 0.22% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $205,311.58 | 3,086 | BQS9486 |
| 0.22% | FOLD | AMICUS THERAPEUTICS INC | -- | $204,301.98 | 14,247 | B19FQ48 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $195,065.64 | 7,812 | 2713317 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $193,809.69 | 5,763 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $190,134.98 | 4,382 | BDD19F8 |
| -- | -- | NEWAMSTERDAM PHARMA CO NV | -- | $183,312.36 | 5,236 | BP8JSP4 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $179,493.48 | 2,532 | BM9HHL5 |
| 0.19% | ERAS | ERASCA INC | -- | $176,339.46 | 13,101 | BNLYBF3 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $173,973.51 | 909 | 2501578 |
| 0.19% | ADMA | ADMA BIOLOGICS INC | -- | $172,323.20 | 10,990 | B9NSBM2 |
| 0.19% | TERN | TERNS PHARMACEUTICALS INC | -- | $172,140.80 | 4,160 | BMDJ0C9 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $159,043.60 | 3,568 | BRJ3GY4 |
| 0.17% | SYRE | SPYRE THERAPEUTICS INC | -- | $157,222.04 | 3,583 | BQBBDY8 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $152,768.56 | 5,656 | BKX9VD3 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $150,947.88 | 6,772 | BD2B4V0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $149,135.36 | 2,648 | B72ZBG4 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $147,256.68 | 4,889 | BKY5JZ8 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $142,466.65 | 1,961 | BMH5RL1 |
| 0.15% | TWST | TWIST BIOSCIENCE CORP | -- | $139,964.34 | 2,823 | BGKG6G7 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $138,722.85 | 4,685 | BK6L288 |
| 0.14% | ALMS | ALUMIS INC | -- | $131,931.71 | 4,489 | BPLQG36 |
| 0.14% | VCYT | VERACYTE INC | -- | $130,378.00 | 3,650 | BFTWZY0 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $128,200.16 | 4,048 | BK0VHF6 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $125,071.38 | 5,839 | BYTQ6X1 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $122,956.00 | 2,950 | BL55460 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $121,203.54 | 4,131 | BLFGJD5 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $120,151.35 | 4,455 | BLB0YQ9 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $116,656.16 | 1,744 | BMGJZJ8 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $114,264.29 | 7,049 | BJ5FZ74 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $112,292.42 | 7,723 | BYZG9R0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $106,806.42 | 3,654 | BP9N0G0 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $106,113.55 | 6,595 | BN15WD1 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $105,751.14 | 5,379 | BKS3RS7 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $104,945.06 | 2,222 | BSRK699 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $102,064.05 | 4,455 | BJ62Z18 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $93,649.00 | 2,638 | BJQ05Z6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $93,451.50 | 9,837 | BNZB1X8 |
| 0.10% | GRAL | GRAIL INC | -- | $93,222.00 | 1,800 | BSLSSX7 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $91,776.86 | 4,838 | B8DPDT7 |
| 0.10% | HROW | HARROW INC | -- | $91,382.40 | 1,710 | BHNDW86 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $89,511.11 | 23,743 | BM9FJ13 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $89,197.36 | 2,086 | BRXB0C0 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $87,849.84 | 6,088 | BFWLC09 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $87,531.20 | 3,632 | BMZ4LN0 |
| 0.09% | VCEL | VERICEL CORP | -- | $86,605.15 | 2,335 | BSBMN89 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $85,008.00 | 2,464 | BMVNDH9 |
| 0.09% | INVA | INNOVIVA INC | -- | $83,700.72 | 3,453 | BDDXF67 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $83,358.72 | 3,456 | BPCQZY9 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $83,290.50 | 4,014 | BN7Q7R7 |
| 0.09% | PHVS | PHARVARIS NV | -- | $81,729.54 | 2,958 | BMZ2X38 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $80,652.32 | 2,692 | BCBVTX1 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $80,256.48 | 2,741 | BMFD115 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $80,135.76 | 4,548 | BV2DHY6 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $79,123.10 | 1,037 | BCDWBX6 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $79,053.71 | 2,699 | BBC9WC7 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $78,886.08 | 2,236 | BKVF0J2 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $78,545.97 | 6,219 | BP2P6L0 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $78,379.83 | 2,061 | BQKXDX4 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $77,513.29 | 5,171 | BYSS4X4 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $76,671.36 | 3,888 | BMX9K07 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,985.40 | 2,660 | BKSGZN7 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,130.84 | 1,279 | BTJZB49 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $73,897.20 | 4,680 | BMVLGP2 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $73,881.72 | 2,073 | BQXJKH2 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $73,787.66 | 8,003 | BN2R582 |
| 0.08% | ARDX | ARDELYX INC | -- | $73,603.20 | 11,220 | BN89V40 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $73,401.10 | 9,722 | 2100362 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,870.27 | 5,071 | BPCK358 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $72,781.80 | 16,770 | BWJDYK1 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $71,770.16 | 5,348 | BYZM6C2 |
| 0.08% | QURE | UNIQURE NV | -- | $71,550.99 | 2,877 | BJFSR88 |
| 0.08% | NVAX | NOVAVAX INC | -- | $71,513.12 | 7,504 | BJDQXG4 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $70,430.58 | 1,278 | BDRW1L7 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $70,203.90 | 18,330 | BF0DMK7 |
| 0.07% | EYPT | EYEPOINT INC | -- | $67,878.72 | 3,822 | BMGS7L1 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $67,669.00 | 2,450 | BFXC933 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $67,262.56 | 5,921 | BJH9ZN0 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,795.00 | 1,460 | BX7RSN3 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $66,470.20 | 2,201 | BR3T9B6 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $64,802.40 | 2,015 | BLCD809 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $64,502.34 | 2,478 | BQB42H3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,240.00 | 6,424 | BK4PZ38 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $62,771.80 | 3,449 | BYP80F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $62,737.92 | 16,338 | BKM5C84 |
| 0.07% | SEPN | SEPTERNA INC | -- | $61,989.33 | 2,067 | BQNKXX2 |
| 0.07% | ORIC | ORIC PHARMACEUTICALS INC | -- | $60,259.80 | 4,497 | BKVDFF7 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $59,352.34 | 2,122 | BNFWZS4 |
| 0.06% | ALVO | ALVOTECH SA | -- | $59,116.86 | 14,454 | BPNTJ34 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,066.16 | 12,648 | BNC1BX1 |
| 0.06% | SVRA | SAVARA INC | -- | $54,866.80 | 9,395 | BYXGN81 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,396.63 | 3,007 | BP7KZP7 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $53,941.44 | 672 | BNSP8K3 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $52,105.25 | 5,633 | B8K7T65 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $51,819.13 | 4,741 | BLB0YH0 |
| 0.06% | SANA | SANA BIOTECHNOLOGY INC | -- | $51,291.00 | 12,300 | BMFJJ97 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $51,028.92 | 7,662 | BLR7H87 |
| 0.06% | GERN | GERON CORP | -- | $50,698.72 | 29,476 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $50,232.60 | 946 | BL95N25 |
| 0.05% | MNKD | MANNKIND CORP | -- | $49,630.00 | 14,180 | BF081J4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $46,591.56 | 1,986 | B3X26D8 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,031.15 | 3,295 | BMG99Y1 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $45,216.94 | 7,823 | BYWVTY5 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $45,108.00 | 2,864 | BP6C0S2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $44,688.54 | 2,162 | BZ7PJQ1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $44,600.40 | 2,340 | BMNDK09 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,390.74 | 1,906 | BMGTLY5 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $44,300.30 | 2,530 | BQB42F1 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $44,110.44 | 4,266 | BRXYZ57 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $44,092.18 | 13,822 | BL53SR3 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $42,171.36 | 4,564 | BMCR7V2 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $41,558.84 | 1,348 | BKLCWZ3 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $40,852.60 | 8,881 | BZ0QMB7 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,471.20 | 3,285 | BJLKVS6 |
| 0.04% | XNCR | XENCOR INC | -- | $39,510.04 | 3,298 | BGCYWN8 |
| 0.04% | ARVN | ARVINAS INC | -- | $39,419.68 | 2,965 | BDZ30Q0 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $39,174.08 | 2,728 | BM90J52 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,284.24 | 2,264 | BQS7491 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $38,044.90 | 2,777 | BMFX8Y7 |
| 0.04% | OMER | OMEROS CORP | -- | $37,258.12 | 3,274 | B4NB858 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $36,783.84 | 2,334 | BD06CS0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $36,756.54 | 11,038 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $36,663.84 | 1,656 | BT9K6D8 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $35,057.12 | 1,808 | BD9GVY0 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $34,423.55 | 8,335 | BPBJFM7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,394.08 | 4,018 | BYZD465 |
| 0.04% | PSNL | PERSONALIS INC | -- | $34,079.31 | 4,101 | BJQ0608 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,016.47 | 6,683 | BMVV9R5 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $32,371.44 | 4,351 | BMC3HS7 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $29,700.40 | 3,622 | BDDVW37 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,141.28 | 3,717 | BFYQFJ2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $29,011.56 | 838 | BQD3J33 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $28,851.10 | 2,630 | BMFK3H6 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $26,693.90 | 7,715 | BN4JN37 |
| 0.03% | CRMD | CORMEDIX INC | -- | $26,593.78 | 3,638 | BJ0LT31 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $26,253.81 | 10,377 | BFZNYB7 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $26,168.96 | 2,638 | BKLXFX5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,240.32 | 7,512 | B3MZ6K5 |
| 0.03% | KMDA | KAMADA LTD | -- | $24,801.84 | 2,664 | B2Q9833 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $23,520.35 | 3,953 | BMXNGZ6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $23,320.62 | 5,633 | BYVQJ96 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $23,219.30 | 3,370 | BQ6C357 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,218.00 | 2,600 | BLFBZ32 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $22,986.92 | 979 | BTNMG41 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,725.36 | 668 | B292NQ7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $22,723.83 | 13,941 | B4N8MH9 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $22,703.38 | 3,598 | BQHN6C7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $22,596.12 | 2,729 | B12W3P6 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,487.60 | 3,307 | 2107437 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $22,441.02 | 2,499 | BJDX8Z9 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $22,066.80 | 2,485 | B91XRN2 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $21,974.64 | 4,819 | BFY7DC4 |
| 0.02% | IVVD | INVIVYD INC | -- | $21,881.16 | 12,796 | BM8NHS1 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $21,868.35 | 1,239 | BGL0JK3 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,828.96 | 6,696 | BMCWKZ2 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $21,606.70 | 4,990 | BDFKQ07 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $21,399.32 | 1,406 | BM7V485 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,144.70 | 1,765 | BP81RK8 |
| 0.02% | PEPG | PEPGEN INC | -- | $20,320.00 | 3,175 | BMTX3D7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,967.04 | 864 | BPBPCG8 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,934.61 | 2,337 | BZ0G875 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $19,500.48 | 1,332 | B9L5200 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $19,311.30 | 2,495 | BRCFFK6 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $19,102.90 | 1,445 | BQV0J03 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,026.56 | 6,944 | BN94K69 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $18,150.00 | 4,125 | BYTYP72 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,863.68 | 2,326 | B7F2TY6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,650.64 | 2,932 | BP81R42 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,837.26 | 1,067 | BPRBTY7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $16,664.34 | 3,607 | BLN9Z50 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,559.93 | 5,003 | BYV2W40 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,366.07 | 2,023 | BSMLR16 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $16,301.12 | 9,262 | BFMLGR4 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $15,747.28 | 4,801 | BKRRKY7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,620.44 | 2,981 | BMVBZF5 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $15,513.05 | 4,445 | BK5MWR1 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,143.80 | 2,611 | BMF7DT9 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,364.35 | 715 | BS2F741 |
| 0.01% | EOLS | EVOLUS INC | -- | $13,468.50 | 2,993 | BDRJH21 |
| 0.01% | CADL | CANDEL THERAPEUTICS INC | -- | $13,131.30 | 2,535 | BP0TQC5 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $12,795.36 | 4,636 | BZC0D70 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,680.90 | 1,730 | 2517058 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $12,494.68 | 778 | BRJJYT3 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,441.90 | 1,005 | BTXQTX3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $12,395.75 | 4,475 | BKX9NQ0 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $12,239.28 | 2,136 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $11,898.13 | 6,647 | BN13S71 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,604.15 | 2,169 | BL5B6Z1 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,340.45 | 2,607 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $11,128.89 | 2,721 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,889.60 | 1,312 | BKC9SX3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $10,030.52 | 8,647 | BMYTJP4 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,602.04 | 4,508 | BZ8FPH3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,376.08 | 5,581 | BRK0149 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,940.60 | 9,030 | BNR5QT9 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,778.16 | 1,432 | BP2NYN2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,496.62 | 3,511 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,416.20 | 4,316 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,814.29 | 2,631 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,080.40 | 4,504 | BNNXX18 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,584.46 | 2,471 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $4,671.52 | 4,171 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $4,628.18 | 7,688 | BNNXX52 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $4,370.00 | 2,875 | BLBR8D5 |
| -- | GOSS | GOSSAMER BIO INC | -- | $4,062.13 | 10,687 | BJ0CK86 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $20.44 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,261,780 | -- | 6,179 | -- |
| -- | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,624,172 | -- | 4,415 | -- |
| -- | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,986,802 | -- | 3,646 | -- |
| -- | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,914,199 | -- | 2,639 | -- |
| -- | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,979,489 | -- | 2,484 | -- |
| -- | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,817,237 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $29,167,625.00 | 29,167,625 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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