BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/19/2026- NAV $87.42
- NAV Change $+0.39
- Market Price $87.38
- Market Price Change $+0.33
- Trading Volume (M) 9,740
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/19/2026- NAV $87.42
- NAV Change $+0.39
- Market Price $87.38
- Market Price Change $+0.33
- Trading Volume (M) 9,740
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/18/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.76% | GILD | GILEAD SCIENCES INC | -- | $6,180,318.62 | 40,463 | 2369174 |
| 6.12% | AMGN | AMGEN INC | -- | $5,596,840.47 | 14,739 | 2023607 |
| 6.04% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,522,850.33 | 11,743 | 2931034 |
| 4.19% | REGN | REGENERON PHARMACEUTICALS | -- | $3,830,885.76 | 4,836 | 2730190 |
| 2.25% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,057,958.48 | 6,186 | B00FWN1 |
| 1.65% | INSM | INSMED INC | -- | $1,508,984.46 | 9,986 | 2614487 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,333,478.97 | 6,869 | 2455965 |
| 1.26% | ARGX | ARGENX SE - ADR | -- | $1,152,212.05 | 1,363 | BDVLM39 |
| 1.05% | UTHR | UNITED THERAPEUTICS CORP | -- | $959,716.80 | 2,016 | 2430412 |
| 1.04% | INCY | INCYTE CORP | -- | $946,684.08 | 9,192 | 2471950 |
| 0.99% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $907,026.70 | 20,005 | BMVP7Y0 |
| 0.99% | RVMD | REVOLUTION MEDICINES INC | -- | $903,299.08 | 9,052 | BL71K91 |
| 0.98% | ROIV | ROIVANT SCIENCES LTD | -- | $894,858.72 | 32,564 | BMW4NZ9 |
| 0.95% | VTRS | VIATRIS INC | -- | $865,544.40 | 53,928 | BMWS3X9 |
| 0.94% | ILMN | ILLUMINA INC | -- | $859,123.86 | 7,154 | 2613990 |
| 0.93% | MRNA | MODERNA INC | -- | $852,407.20 | 18,292 | BGSXTS3 |
| 0.73% | BBIO | BRIDGEBIO PHARMA INC | -- | $666,996.46 | 9,022 | BK1KWG8 |
| 0.71% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $652,136.25 | 2,875 | BV9G6B8 |
| 0.71% | GH | GUARDANT HEALTH INC | -- | $650,750.36 | 6,058 | BFXC911 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $623,556.48 | 7,584 | BDJ0LS6 |
| 0.66% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $599,277.84 | 4,668 | 2623911 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $588,498.23 | 1,319 | BDCBC61 |
| 0.63% | SNY | SANOFI-ADR | -- | $571,674.60 | 12,390 | 2964557 |
| 0.61% | EXEL | EXELIXIS INC | -- | $558,276.38 | 12,554 | 2576941 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $556,160.85 | 8,995 | 2437071 |
| 0.61% | SMMT | SUMMIT THERAPEUTICS INC | -- | $553,513.28 | 34,856 | BMTVQS7 |
| 0.58% | ONC | BEONE MEDICINES LTD-ADR | -- | $529,239.70 | 1,474 | BYYWPW6 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $522,453.87 | 1,063 | BD59BS7 |
| 0.56% | RNA | AVIDITY BIOSCIENCES INC | -- | $513,815.65 | 7,055 | BMWHPY1 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $511,035.30 | 4,734 | BK6H543 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $480,008.40 | 2,845 | B4Q5ZN4 |
| 0.50% | TEM | TEMPUS AI INC | -- | $454,559.04 | 8,094 | BSLSJJ0 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $435,986.40 | 2,360 | BYZR4X4 |
| 0.45% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $409,392.42 | 6,359 | BYQBFJ8 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $403,204.38 | 5,506 | 2975098 |
| 0.43% | IBRX | IMMUNITYBIO INC | -- | $393,847.72 | 46,118 | BNSP0B8 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $385,177.03 | 1,171 | BQ721R4 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $384,707.82 | 1,358 | BD6JX35 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $383,460.50 | 5,725 | BBBSBJ5 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $350,972.72 | 2,764 | BLC89B2 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $346,181.52 | 3,382 | BMVBZD3 |
| 0.38% | PCVX | VAXCYTE INC | -- | $344,265.93 | 6,129 | BKPVGH6 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $316,562.50 | 3,125 | BF2YWG4 |
| 0.31% | KYMR | KYMERA THERAPEUTICS INC | -- | $286,735.59 | 3,369 | BMPRZV5 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $278,091.55 | 13,211 | BT18HP9 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $275,621.45 | 7,187 | BLR6XK8 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $259,107.87 | 3,759 | B17VCN9 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $252,870.60 | 2,406 | BJDX8Y8 |
| 0.27% | ALKS | ALKERMES PLC | -- | $247,546.62 | 7,731 | B3P6D26 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $242,911.73 | 2,927 | BDCBCD8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $238,806.24 | 4,462 | BDHF4K6 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $224,280.96 | 4,776 | BFZQ0L8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $218,716.55 | 8,207 | BJRFSB7 |
| 0.24% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $218,577.15 | 14,719 | BFNF1D6 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $213,898.44 | 3,129 | BQS9486 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $208,528.17 | 3,777 | BRBCSP4 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $207,155.64 | 14,446 | B19FQ48 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $200,799.84 | 5,844 | BTZRLN8 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $193,048.35 | 4,443 | BDD19F8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $189,849.84 | 5,309 | BP8JSP4 |
| 0.20% | ACLX | ARCELLX INC | -- | $186,891.28 | 2,707 | BPCJ1Q2 |
| 0.20% | GRAL | GRAIL INC | -- | $186,661.00 | 1,825 | BSLSSX7 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $183,767.20 | 7,921 | 2713317 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $180,383.09 | 2,567 | BM9HHL5 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $178,192.56 | 11,144 | B9NSBM2 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $175,124.68 | 922 | 2501578 |
| 0.18% | ERAS | ERASCA INC | -- | $168,175.44 | 13,284 | BNLYBF3 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $165,978.30 | 4,218 | BMDJ0C9 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $157,235.96 | 2,863 | BGKG6G7 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $153,801.18 | 3,618 | BRJ3GY4 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $153,181.85 | 5,735 | BKX9VD3 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $149,453.55 | 4,957 | BKY5JZ8 |
| 0.15% | VCYT | VERACYTE INC | -- | $135,493.61 | 3,701 | BFTWZY0 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $134,787.00 | 2,685 | B72ZBG4 |
| 0.15% | SYRE | SPYRE THERAPEUTICS INC | -- | $132,967.80 | 3,633 | BQBBDY8 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $132,052.41 | 6,867 | BD2B4V0 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $131,813.37 | 2,991 | BL55460 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $131,446.20 | 5,921 | BYTQ6X1 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $130,937.56 | 4,751 | BK6L288 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $126,926.60 | 4,105 | BK0VHF6 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $125,780.76 | 1,988 | BMH5RL1 |
| 0.14% | ALMS | ALUMIS INC | -- | $125,225.52 | 4,552 | BPLQG36 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $116,747.43 | 4,189 | BLFGJD5 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $114,000.64 | 1,768 | BMGJZJ8 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $113,438.76 | 7,148 | BJ5FZ74 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $113,105.68 | 4,517 | BLB0YQ9 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $106,734.78 | 5,454 | BKS3RS7 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $103,517.70 | 3,705 | BP9N0G0 |
| 0.11% | DYN | DYNE THERAPEUTICS INC | -- | $102,846.06 | 6,687 | BN15WD1 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $102,507.79 | 7,831 | BYZG9R0 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $101,565.24 | 2,253 | BSRK699 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $95,999.85 | 2,115 | BRXB0C0 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $95,150.16 | 2,697 | BKSGZN7 |
| 0.10% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $92,372.65 | 4,517 | BJ62Z18 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $90,172.28 | 4,906 | B8DPDT7 |
| 0.10% | VCEL | VERICEL CORP | -- | $88,586.88 | 2,368 | BSBMN89 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,335.63 | 6,173 | BFWLC09 |
| 0.09% | HROW | HARROW INC | -- | $86,474.58 | 1,734 | BHNDW86 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $84,984.75 | 24,075 | BM9FJ13 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $84,731.62 | 2,102 | BQXJKH2 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $82,871.50 | 2,675 | BJQ05Z6 |
| 0.09% | INVA | INNOVIVA INC | -- | $82,833.66 | 3,501 | BDDXF67 |
| 0.09% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $82,536.03 | 3,683 | BMZ4LN0 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $82,417.50 | 4,070 | BN7Q7R7 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $81,856.12 | 1,052 | BCDWBX6 |
| 0.09% | PHVS | PHARVARIS NV | -- | $81,002.99 | 2,999 | BMZ2X38 |
| 0.09% | PGEN | PRECIGEN INC | -- | $80,846.96 | 16,567 | BKM5C84 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $80,276.64 | 3,504 | BPCQZY9 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $80,156.56 | 4,612 | BV2DHY6 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $79,810.92 | 2,737 | BBC9WC7 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $78,855.70 | 2,090 | BQKXDX4 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $78,257.46 | 6,306 | BP2P6L0 |
| 0.09% | MNKD | MANNKIND CORP | -- | $78,216.32 | 14,378 | BF081J4 |
| 0.08% | ARDX | ARDELYX INC | -- | $76,453.44 | 11,377 | BN89V40 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $75,238.80 | 2,730 | BCBVTX1 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,888.78 | 1,297 | BTJZB49 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $73,846.50 | 8,115 | BN2R582 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $73,470.60 | 2,499 | BMVNDH9 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $73,468.08 | 4,746 | BMVLGP2 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $73,282.23 | 2,779 | BMFD115 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,156.09 | 2,267 | BKVF0J2 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,502.20 | 5,142 | BPCK358 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,335.70 | 3,942 | BMX9K07 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $71,569.08 | 9,858 | 2100362 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $71,059.68 | 1,296 | BDRW1L7 |
| 0.08% | OCUL | OCULAR THERAPEUTIX INC | -- | $68,628.00 | 9,975 | BNZB1X8 |
| 0.07% | QURE | UNIQURE NV | -- | $68,345.31 | 2,917 | BJFSR88 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $67,679.04 | 5,423 | BYZM6C2 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $67,169.75 | 17,005 | BWJDYK1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $67,046.84 | 2,513 | BQB42H3 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $67,029.20 | 1,480 | BX7RSN3 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $66,417.93 | 2,043 | BLCD809 |
| 0.07% | NVAX | NOVAVAX INC | -- | $66,122.21 | 7,609 | BJDQXG4 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,174.40 | 2,232 | BR3T9B6 |
| 0.07% | ALVO | ALVOTECH SA | -- | $64,046.72 | 14,656 | BPNTJ34 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $63,260.73 | 3,497 | BYP80F1 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $61,676.32 | 2,152 | BNFWZS4 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $61,180.76 | 6,004 | BJH9ZN0 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $61,056.72 | 2,484 | BFXC933 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $59,770.20 | 5,243 | BYSS4X4 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,636.25 | 12,825 | BNC1BX1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $59,316.80 | 2,096 | BQNKXX2 |
| 0.06% | GERN | GERON CORP | -- | $57,984.66 | 29,889 | 2370381 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $55,735.72 | 3,049 | BP7KZP7 |
| 0.06% | EYPT | EYEPOINT INC | -- | $55,659.36 | 3,876 | BMGS7L1 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $55,568.92 | 4,807 | BLB0YH0 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $55,555.98 | 681 | BNSP8K3 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $55,520.64 | 5,712 | B8K7T65 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $54,616.07 | 7,769 | BLR7H87 |
| 0.06% | SVRA | SAVARA INC | -- | $53,255.93 | 9,527 | BYXGN81 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $51,004.62 | 6,514 | BK4PZ38 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $50,556.64 | 18,587 | BF0DMK7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $49,384.80 | 4,560 | BKVDFF7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $49,014.96 | 12,472 | BMFJJ97 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $48,985.72 | 959 | BL95N25 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $48,815.84 | 2,192 | BZ7PJQ1 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $46,754.40 | 2,904 | BP6C0S2 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,640.36 | 3,341 | BMG99Y1 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $46,362.28 | 2,014 | B3X26D8 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $46,026.89 | 1,367 | BKLCWZ3 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $45,490.41 | 2,373 | BMNDK09 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $45,163.44 | 4,326 | BRXYZ57 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,942.25 | 1,933 | BMGTLY5 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $43,866.95 | 14,015 | BL53SR3 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $43,734.60 | 4,628 | BMCR7V2 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $42,917.53 | 7,933 | BYWVTY5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $39,959.01 | 11,193 | BBNBTD2 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $39,572.28 | 3,331 | BJLKVS6 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $39,123.84 | 2,296 | BQS7491 |
| 0.04% | OMER | OMEROS CORP | -- | $39,010.00 | 3,320 | B4NB858 |
| 0.04% | XNCR | XENCOR INC | -- | $37,920.96 | 3,344 | BGCYWN8 |
| 0.04% | PSNL | PERSONALIS INC | -- | $37,422.00 | 4,158 | BJQ0608 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $37,281.40 | 4,412 | BMC3HS7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $37,199.36 | 2,816 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,190.65 | 9,005 | BZ0QMB7 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $37,166.85 | 2,565 | BQB42F1 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $36,989.94 | 1,833 | BD9GVY0 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $36,570.15 | 2,367 | BD06CS0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $36,409.26 | 7,617 | B3MZ6K5 |
| 0.04% | ARVN | ARVINAS INC | -- | $35,542.74 | 3,007 | BDZ30Q0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,588.26 | 4,074 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,409.04 | 2,766 | BM90J52 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,291.62 | 6,777 | BMVV9R5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,891.61 | 1,679 | BT9K6D8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $30,362.00 | 850 | BQD3J33 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $29,530.92 | 3,673 | BDDVW37 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,305.19 | 3,769 | BFYQFJ2 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $28,084.57 | 7,823 | BN4JN37 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $27,807.08 | 8,452 | BPBJFM7 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $27,721.96 | 2,534 | BJDX8Z9 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,750.01 | 2,667 | BMFK3H6 |
| 0.03% | CRMD | CORMEDIX INC | -- | $26,450.13 | 3,689 | BJ0LT31 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $24,529.75 | 2,675 | BKLXFX5 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $24,219.27 | 993 | BTNMG41 |
| 0.03% | KMDA | KAMADA LTD | -- | $23,903.85 | 2,701 | B2Q9833 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $23,884.94 | 10,522 | BFZNYB7 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $23,516.29 | 10,837 | BJ0CK86 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $23,417.43 | 677 | B292NQ7 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $23,058.42 | 1,426 | BM7V485 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $23,041.68 | 14,136 | B4N8MH9 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,906.80 | 2,520 | B91XRN2 |
| 0.02% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,801.40 | 2,636 | BLFBZ32 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,398.04 | 3,353 | 2107437 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,876.96 | 5,712 | BYVQJ96 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $21,791.56 | 4,886 | BFY7DC4 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $21,615.76 | 1,256 | BGL0JK3 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $21,596.16 | 3,648 | BQHN6C7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,492.93 | 3,417 | BQ6C357 |
| 0.02% | IVVD | INVIVYD INC | -- | $21,408.75 | 12,975 | BM8NHS1 |
| 0.02% | PEPG | PEPGEN INC | -- | $21,052.26 | 3,219 | BMTX3D7 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $20,973.70 | 2,530 | BRCFFK6 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,234.20 | 6,790 | BMCWKZ2 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,761.60 | 1,790 | BP81RK8 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,010.70 | 7,041 | BN94K69 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,765.39 | 1,351 | B9L5200 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,723.00 | 2,370 | BZ0G875 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $18,708.05 | 1,465 | BQV0J03 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $18,501.12 | 876 | BPBPCG8 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,457.00 | 5,060 | BDFKQ07 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,899.32 | 4,183 | BYTYP72 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $16,826.80 | 3,658 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,685.01 | 2,767 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,468.04 | 1,082 | BPRBTY7 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,081.41 | 5,073 | BYV2W40 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $16,015.72 | 4,868 | BKRRKY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,758.12 | 2,359 | B7F2TY6 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $15,751.68 | 2,051 | BSMLR16 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,205.69 | 3,023 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,034.50 | 2,570 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,987.68 | 2,648 | BMF7DT9 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,983.92 | 2,973 | BP81R42 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $14,651.52 | 9,392 | BFMLGR4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,106.91 | 4,507 | BK5MWR1 |
| 0.01% | EOLS | EVOLUS INC | -- | $13,171.90 | 3,035 | BDRJH21 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,890.35 | 1,019 | BTXQTX3 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,734.04 | 1,754 | 2517058 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,477.25 | 725 | BS2F741 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $12,316.62 | 4,701 | BZC0D70 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $11,823.60 | 4,008 | BMXNGZ6 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,653.08 | 2,166 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $11,525.40 | 6,740 | BN13S71 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,687.14 | 2,199 | BL5B6Z1 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,576.00 | 2,644 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,414.80 | 789 | BRJJYT3 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,988.30 | 1,330 | BKC9SX3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,469.44 | 8,768 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,224.17 | 5,659 | BRK0149 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,215.06 | 2,759 | BY7RB53 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,667.58 | 4,538 | BKX9NQ0 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,299.00 | 9,156 | BNR5QT9 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,862.12 | 4,571 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,623.00 | 1,452 | BP2NYN2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $7,298.00 | 3,560 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,089.12 | 4,376 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,029.68 | 2,668 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,937.10 | 4,567 | BNNXX18 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,087.18 | 2,506 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $4,947.93 | 4,229 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $4,920.06 | 7,796 | BNNXX52 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,993.55 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $17.43 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 41.52% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,941,817 | -- | 6,327 | -- |
| 28.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,475,916 | -- | 4,415 | -- |
| 22.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,754,959 | -- | 3,461 | -- |
| 17.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,825,582 | -- | 2,639 | -- |
| 16.30% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,896,076 | -- | 2,484 | -- |
| 4.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,795,981 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,583,572.06 | 28,583,572 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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