BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/13/2026- NAV $84.77
- NAV Change $+1.66
- Market Price $84.72
- Market Price Change $+1.63
- Trading Volume (M) 5,106
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/13/2026- NAV $84.77
- NAV Change $+1.66
- Market Price $84.72
- Market Price Change $+1.63
- Trading Volume (M) 5,106
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/13/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 7.05% | GILD | GILEAD SCIENCES INC | -- | $6,270,955.74 | 40,463 | 2369174 |
| 6.48% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,771,332.21 | 11,743 | 2931034 |
| 6.11% | AMGN | AMGEN INC | -- | $5,441,491.41 | 14,739 | 2023607 |
| 4.36% | REGN | REGENERON PHARMACEUTICALS | -- | $3,884,130.12 | 4,836 | 2730190 |
| 2.19% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,944,878.40 | 6,186 | B00FWN1 |
| 1.67% | INSM | INSMED INC | -- | $1,485,417.50 | 9,986 | 2614487 |
| 1.52% | BIIB | BIOGEN INC | -- | $1,349,895.88 | 6,869 | 2455965 |
| 1.26% | ARGX | ARGENX SE - ADR | -- | $1,120,331.48 | 1,363 | BDVLM39 |
| 1.07% | UTHR | UNITED THERAPEUTICS CORP | -- | $954,898.56 | 2,016 | 2430412 |
| 1.04% | INCY | INCYTE CORP | -- | $929,311.20 | 9,192 | 2471950 |
| 1.02% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $904,025.95 | 20,005 | BMVP7Y0 |
| 0.98% | RVMD | REVOLUTION MEDICINES INC | -- | $871,798.12 | 9,052 | BL71K91 |
| 0.97% | ROIV | ROIVANT SCIENCES LTD | -- | $861,317.80 | 32,564 | BMW4NZ9 |
| 0.96% | VTRS | VIATRIS INC | -- | $850,444.56 | 53,928 | BMWS3X9 |
| 0.94% | ILMN | ILLUMINA INC | -- | $835,658.74 | 7,154 | 2613990 |
| 0.87% | MRNA | MODERNA INC | -- | $772,471.16 | 18,292 | BGSXTS3 |
| 0.76% | BBIO | BRIDGEBIO PHARMA INC | -- | $678,905.50 | 9,022 | BK1KWG8 |
| 0.71% | GH | GUARDANT HEALTH INC | -- | $635,181.30 | 6,058 | BFXC911 |
| 0.70% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $621,920.00 | 2,875 | BV9G6B8 |
| 0.69% | IONS | IONIS PHARMACEUTICALS INC | -- | $611,270.40 | 7,584 | BDJ0LS6 |
| 0.65% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $579,392.16 | 4,668 | 2623911 |
| 0.64% | SNY | SANOFI-ADR | -- | $570,063.90 | 12,390 | 2964557 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $564,571.57 | 1,319 | BDCBC61 |
| 0.62% | EXEL | EXELIXIS INC | -- | $551,371.68 | 12,554 | 2576941 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $538,530.65 | 8,995 | 2437071 |
| 0.59% | SMMT | SUMMIT THERAPEUTICS INC | -- | $521,445.76 | 34,856 | BMTVQS7 |
| 0.58% | RNA | AVIDITY BIOSCIENCES INC | -- | $514,097.85 | 7,055 | BMWHPY1 |
| 0.57% | ONC | BEONE MEDICINES LTD-ADR | -- | $510,107.18 | 1,474 | BYYWPW6 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $501,188.58 | 4,734 | BK6H543 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $493,986.73 | 1,063 | BD59BS7 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $473,151.95 | 2,845 | B4Q5ZN4 |
| 0.49% | HALO | HALOZYME THERAPEUTICS INC | -- | $437,396.64 | 5,506 | 2975098 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $427,655.60 | 2,360 | BYZR4X4 |
| 0.47% | TEM | TEMPUS AI INC | -- | $420,483.30 | 8,094 | BSLSJJ0 |
| 0.46% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $405,831.38 | 6,359 | BYQBFJ8 |
| 0.43% | CYTK | CYTOKINETICS INC | -- | $379,338.50 | 5,725 | BBBSBJ5 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $375,419.10 | 1,358 | BD6JX35 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $371,499.75 | 1,171 | BQ721R4 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $345,472.36 | 2,764 | BLC89B2 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $340,973.24 | 3,382 | BMVBZD3 |
| 0.37% | PCVX | VAXCYTE INC | -- | $331,578.90 | 6,129 | BKPVGH6 |
| 0.34% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $306,468.75 | 3,125 | BF2YWG4 |
| 0.31% | KYMR | KYMERA THERAPEUTICS INC | -- | $277,403.46 | 3,369 | BMPRZV5 |
| 0.31% | IBRX | IMMUNITYBIO INC | -- | $274,171.51 | 46,118 | BNSP0B8 |
| 0.31% | CAI | CARIS LIFE SCIENCES INC | -- | $272,410.82 | 13,211 | BT18HP9 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $262,541.11 | 7,187 | BLR6XK8 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $261,062.55 | 3,759 | B17VCN9 |
| 0.29% | ALKS | ALKERMES PLC | -- | $256,359.96 | 7,731 | B3P6D26 |
| 0.28% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $248,058.60 | 2,406 | BJDX8Y8 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $238,521.23 | 2,927 | BDCBCD8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $236,798.34 | 4,462 | BDHF4K6 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $219,600.48 | 4,776 | BFZQ0L8 |
| 0.25% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $219,249.03 | 3,129 | BQS9486 |
| 0.25% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $218,135.58 | 14,719 | BFNF1D6 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $211,330.25 | 8,207 | BJRFSB7 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $206,722.26 | 14,446 | B19FQ48 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $202,085.52 | 5,844 | BTZRLN8 |
| 0.22% | CGON | CG ONCOLOGY INC | -- | $194,515.50 | 3,777 | BRBCSP4 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $189,716.10 | 4,443 | BDD19F8 |
| 0.21% | ACLX | ARCELLX INC | -- | $185,429.50 | 2,707 | BPCJ1Q2 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $183,850.67 | 5,309 | BP8JSP4 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $179,306.96 | 11,144 | B9NSBM2 |
| 0.20% | GRAL | GRAIL INC | -- | $177,937.50 | 1,825 | BSLSSX7 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $174,499.63 | 7,921 | 2713317 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $173,991.26 | 2,567 | BM9HHL5 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $169,491.26 | 922 | 2501578 |
| 0.18% | ERAS | ERASCA INC | -- | $159,408.00 | 13,284 | BNLYBF3 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $159,398.22 | 4,218 | BMDJ0C9 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $150,074.64 | 3,618 | BRJ3GY4 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $148,759.57 | 4,957 | BKY5JZ8 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $148,307.10 | 5,735 | BKX9VD3 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $140,601.93 | 2,863 | BGKG6G7 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $136,505.40 | 2,685 | B72ZBG4 |
| 0.15% | SYRE | SPYRE THERAPEUTICS INC | -- | $133,076.79 | 3,633 | BQBBDY8 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $132,647.92 | 4,751 | BK6L288 |
| 0.15% | VCYT | VERACYTE INC | -- | $132,384.77 | 3,701 | BFTWZY0 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $128,893.59 | 6,867 | BD2B4V0 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $128,485.70 | 5,921 | BYTQ6X1 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $126,280.02 | 2,991 | BL55460 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $124,258.35 | 4,105 | BK0VHF6 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $120,830.64 | 1,988 | BMH5RL1 |
| 0.14% | ALMS | ALUMIS INC | -- | $120,810.08 | 4,552 | BPLQG36 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $116,537.98 | 4,189 | BLFGJD5 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $114,653.92 | 7,148 | BJ5FZ74 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $111,615.07 | 4,517 | BLB0YQ9 |
| 0.12% | DYN | DYNE THERAPEUTICS INC | -- | $103,915.98 | 6,687 | BN15WD1 |
| 0.12% | MAZE | MAZE THERAPEUTICS INC | -- | $103,660.53 | 2,253 | BSRK699 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $102,258.00 | 3,705 | BP9N0G0 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $99,297.08 | 7,831 | BYZG9R0 |
| 0.11% | IRON | DISC MEDICINE INC | -- | $98,919.60 | 1,768 | BMGJZJ8 |
| 0.11% | TXG | 10X GENOMICS INC-CLASS A | -- | $98,826.48 | 5,454 | BKS3RS7 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $97,118.97 | 2,697 | BKSGZN7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $95,957.55 | 2,115 | BRXB0C0 |
| 0.10% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $92,688.84 | 4,517 | BJ62Z18 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $88,578.00 | 9,975 | BNZB1X8 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $87,841.79 | 6,173 | BFWLC09 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $87,277.74 | 4,906 | B8DPDT7 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $85,359.25 | 2,675 | BJQ05Z6 |
| 0.10% | VCEL | VERICEL CORP | -- | $85,153.28 | 2,368 | BSBMN89 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $84,021.75 | 24,075 | BM9FJ13 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $83,353.60 | 4,070 | BN7Q7R7 |
| 0.09% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $83,198.97 | 3,683 | BMZ4LN0 |
| 0.09% | HROW | HARROW INC | -- | $82,694.46 | 1,734 | BHNDW86 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $82,192.11 | 2,737 | BBC9WC7 |
| 0.09% | PGEN | PRECIGEN INC | -- | $81,675.31 | 16,567 | BKM5C84 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $81,382.72 | 1,052 | BCDWBX6 |
| 0.09% | MNKD | MANNKIND CORP | -- | $81,379.48 | 14,378 | BF081J4 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $81,347.40 | 6,306 | BP2P6L0 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $80,065.18 | 2,102 | BQXJKH2 |
| 0.09% | INVA | INNOVIVA INC | -- | $79,472.70 | 3,501 | BDDXF67 |
| 0.09% | PHVS | PHARVARIS NV | -- | $79,323.55 | 2,999 | BMZ2X38 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $79,190.40 | 3,504 | BPCQZY9 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $78,416.80 | 2,090 | BQKXDX4 |
| 0.09% | ARDX | ARDELYX INC | -- | $78,159.99 | 11,377 | BN89V40 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $76,330.80 | 2,730 | BCBVTX1 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,862.84 | 1,297 | BTJZB49 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $74,254.88 | 2,779 | BMFD115 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $74,037.60 | 4,746 | BMVLGP2 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $73,020.07 | 2,267 | BKVF0J2 |
| 0.08% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $72,639.00 | 4,612 | BV2DHY6 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,605.04 | 5,142 | BPCK358 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $72,466.95 | 8,115 | BN2R582 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $69,947.01 | 2,499 | BMVNDH9 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $69,300.36 | 3,942 | BMX9K07 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $68,791.68 | 1,296 | BDRW1L7 |
| 0.08% | ALVO | ALVOTECH SA | -- | $68,003.84 | 14,656 | BPNTJ34 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $67,769.20 | 1,480 | BX7RSN3 |
| 0.07% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $66,640.08 | 9,858 | 2100362 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $66,343.20 | 2,513 | BQB42H3 |
| 0.07% | NVAX | NOVAVAX INC | -- | $66,198.30 | 7,609 | BJDQXG4 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $65,948.04 | 2,043 | BLCD809 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $65,254.02 | 3,497 | BYP80F1 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,371.01 | 5,423 | BYZM6C2 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $62,441.60 | 6,004 | BJH9ZN0 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $62,339.76 | 2,232 | BR3T9B6 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $61,332.00 | 2,152 | BNFWZS4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $60,707.85 | 17,005 | BWJDYK1 |
| 0.07% | QURE | UNIQURE NV | -- | $59,798.50 | 2,917 | BJFSR88 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $58,353.75 | 12,825 | BNC1BX1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $57,640.00 | 2,096 | BQNKXX2 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $57,620.57 | 5,243 | BYSS4X4 |
| 0.06% | KOD | KODIAK SCIENCES INC | -- | $54,821.88 | 2,484 | BFXC933 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,638.08 | 3,049 | BP7KZP7 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $54,559.45 | 4,807 | BLB0YH0 |
| 0.06% | SVRA | SAVARA INC | -- | $53,351.20 | 9,527 | BYXGN81 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $53,235.84 | 5,712 | B8K7T65 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $52,984.58 | 7,769 | BLR7H87 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,619.80 | 681 | BNSP8K3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,155.44 | 3,876 | BMGS7L1 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $50,117.34 | 959 | BL95N25 |
| 0.06% | GERN | GERON CORP | -- | $49,316.85 | 29,889 | 2370381 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $48,659.58 | 6,514 | BK4PZ38 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $48,017.20 | 12,472 | BMFJJ97 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $47,768.59 | 18,587 | BF0DMK7 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,673.77 | 3,341 | BMG99Y1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,344.69 | 2,373 | BMNDK09 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $45,554.40 | 4,560 | BKVDFF7 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $45,316.05 | 1,367 | BKLCWZ3 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $44,059.20 | 2,192 | BZ7PJQ1 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,844.78 | 2,014 | B3X26D8 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $43,446.50 | 14,015 | BL53SR3 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $43,415.18 | 1,933 | BMGTLY5 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $42,688.80 | 2,904 | BP6C0S2 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $42,351.54 | 4,326 | BRXYZ57 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $42,203.56 | 7,933 | BYWVTY5 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $40,957.80 | 4,628 | BMCR7V2 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,038.62 | 3,331 | BJLKVS6 |
| 0.04% | OMER | OMEROS CORP | -- | $38,810.80 | 3,320 | B4NB858 |
| 0.04% | XNCR | XENCOR INC | -- | $38,756.96 | 3,344 | BGCYWN8 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $38,391.99 | 11,193 | BBNBTD2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $38,274.32 | 2,296 | BQS7491 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $37,002.24 | 2,816 | BMFX8Y7 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $36,714.99 | 1,833 | BD9GVY0 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $36,448.65 | 2,565 | BQB42F1 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $35,839.90 | 9,005 | BZ0QMB7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $35,291.97 | 2,367 | BD06CS0 |
| 0.04% | ARVN | ARVINAS INC | -- | $35,031.55 | 3,007 | BDZ30Q0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $34,276.50 | 7,617 | B3MZ6K5 |
| 0.04% | PSNL | PERSONALIS INC | -- | $34,137.18 | 4,158 | BJQ0608 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,854.94 | 4,074 | BYZD465 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,139.53 | 6,777 | BMVV9R5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,858.03 | 1,679 | BT9K6D8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $32,057.94 | 2,766 | BM90J52 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $29,273.81 | 3,673 | BDDVW37 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $29,172.00 | 850 | BQD3J33 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,079.05 | 3,769 | BFYQFJ2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $27,891.60 | 8,452 | BPBJFM7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $27,077.26 | 3,689 | BJ0LT31 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $26,936.42 | 2,534 | BJDX8Z9 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,856.69 | 2,667 | BMFK3H6 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $25,659.12 | 993 | BTNMG41 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $25,633.72 | 4,412 | BMC3HS7 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $25,033.60 | 7,823 | BN4JN37 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $25,011.25 | 2,675 | BKLXFX5 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $24,816.73 | 10,837 | BJ0CK86 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $24,172.56 | 14,136 | B4N8MH9 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $23,643.08 | 1,426 | BM7V485 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,963.84 | 677 | B292NQ7 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,958.50 | 2,701 | B2Q9833 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,766.87 | 3,353 | 2107437 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,581.12 | 3,648 | BQHN6C7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,579.20 | 2,520 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,406.00 | 2,636 | BLFBZ32 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $22,137.50 | 2,530 | BRCFFK6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $22,133.58 | 4,886 | BFY7DC4 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,561.27 | 3,417 | BQ6C357 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $21,439.92 | 1,256 | BGL0JK3 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,848.80 | 5,712 | BYVQJ96 |
| 0.02% | PEPG | PEPGEN INC | -- | $20,730.36 | 3,219 | BMTX3D7 |
| 0.02% | IVVD | INVIVYD INC | -- | $20,241.00 | 12,975 | BM8NHS1 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,098.40 | 6,790 | BMCWKZ2 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,517.28 | 876 | BPBPCG8 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,475.20 | 1,790 | BP81RK8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $18,939.60 | 10,522 | BFZNYB7 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,936.30 | 2,370 | BZ0G875 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $18,869.20 | 1,465 | BQV0J03 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,711.35 | 1,351 | B9L5200 |
| 0.02% | ABSI | ABSCI CORP | -- | $17,954.55 | 7,041 | BN94K69 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,851.03 | 2,767 | B12W3P6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,559.61 | 2,973 | BP81R42 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,546.20 | 5,060 | BDFKQ07 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,439.19 | 4,183 | BYTYP72 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,182.87 | 5,073 | BYV2W40 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $16,088.38 | 2,359 | B7F2TY6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $15,765.98 | 3,658 | BLN9Z50 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $15,626.28 | 4,868 | BKRRKY7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,624.08 | 1,082 | BPRBTY7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,903.39 | 3,023 | BMVBZF5 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $14,890.26 | 2,051 | BSMLR16 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,696.40 | 2,648 | BMF7DT9 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $14,597.60 | 2,570 | BP0TQC5 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,055.99 | 4,701 | BZC0D70 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,148.80 | 9,392 | BFMLGR4 |
| 0.01% | EOLS | EVOLUS INC | -- | $13,050.50 | 3,035 | BDRJH21 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,625.20 | 4,008 | BMXNGZ6 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $12,619.60 | 4,507 | BK5MWR1 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,600.50 | 725 | BS2F741 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,418.32 | 1,754 | 2517058 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,329.90 | 1,019 | BTXQTX3 |
| 0.01% | OABI | OMNIAB INC | -- | $11,458.00 | 6,740 | BN13S71 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $11,349.84 | 2,166 | BKDQKM6 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,126.52 | 2,644 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,083.42 | 789 | BRJJYT3 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,785.55 | 2,199 | BL5B6Z1 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,589.30 | 1,330 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,353.01 | 2,759 | BY7RB53 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $9,110.99 | 5,659 | BRK0149 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $9,069.93 | 9,156 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,855.68 | 8,768 | BMYTJP4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,576.82 | 4,538 | BKX9NQ0 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,044.96 | 4,571 | BZ8FPH3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,347.12 | 1,452 | BP2NYN2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,914.08 | 4,376 | BNYJR68 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,922.96 | 2,668 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,663.08 | 4,567 | BNNXX18 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,518.00 | 3,560 | BPTK6Z2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,145.36 | 7,796 | BNNXX52 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,074.80 | 4,229 | B5LL2C2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,012.00 | 2,506 | BP7L561 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $3,789.50 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $16.16 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 39.60% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 35,243,081 | -- | 5,956 | -- |
| 29.35% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,124,615 | -- | 4,415 | -- |
| 23.01% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,479,568 | -- | 3,461 | -- |
| 17.54% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,615,596 | -- | 2,639 | -- |
| 16.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,698,424 | -- | 2,484 | -- |
| 4.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,745,613 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $27,043,405.89 | 27,043,406 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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