BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,520,780
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/09/2026- NAV
- NAV Change
- Market Price $81.08
- Market Price Change $+2.42
- Trading Volume (M) 8,255
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $70,520,780
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/09/2026- NAV
- NAV Change
- Market Price $81.08
- Market Price Change $+2.42
- Trading Volume (M) 8,255
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/09/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.84% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,413,260.89 | 7,657 | 2931034 |
| 4.79% | AMGN | AMGEN INC | -- | $3,377,770.70 | 9,803 | 2023607 |
| 4.55% | GILD | GILEAD SCIENCES INC | -- | $3,205,521.00 | 25,542 | 2369174 |
| 3.36% | REGN | REGENERON PHARMACEUTICALS | -- | $2,366,131.20 | 3,840 | 2730190 |
| 2.07% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,459,871.76 | 4,904 | B00FWN1 |
| 1.55% | RVMD | REVOLUTION MEDICINES INC | -- | $1,095,603.30 | 7,326 | BL71K91 |
| 1.53% | BIIB | BIOGEN INC | -- | $1,080,117.50 | 5,425 | 2455965 |
| 1.32% | ARGX | ARGENX SE - ADR | -- | $928,200.00 | 1,050 | BDVLM39 |
| 1.28% | ILMN | ILLUMINA INC | -- | $904,649.59 | 5,653 | 2613990 |
| 1.27% | UTHR | UNITED THERAPEUTICS CORP | -- | $896,086.80 | 1,620 | 2430412 |
| 1.25% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $881,012.31 | 15,837 | BMVP7Y0 |
| 1.12% | INSM | INSMED INC | -- | $789,150.72 | 7,968 | 2614487 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $768,663.00 | 26,460 | BMW4NZ9 |
| 1.08% | INCY | INCYTE CORP | -- | $759,669.57 | 7,359 | 2471950 |
| 0.99% | MRNA | MODERNA INC | -- | $696,858.00 | 14,600 | BGSXTS3 |
| 0.98% | VTRS | VIATRIS INC | -- | $689,553.00 | 42,565 | BMWS3X9 |
| 0.89% | GH | GUARDANT HEALTH INC | -- | $631,082.00 | 4,850 | BFXC911 |
| 0.87% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $613,370.88 | 3,712 | 2623911 |
| 0.74% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $521,407.25 | 2,275 | B4Q5ZN4 |
| 0.72% | EXEL | EXELIXIS INC | -- | $508,704.00 | 9,600 | 2576941 |
| 0.70% | MEDP | MEDPACE HOLDINGS INC | -- | $490,596.29 | 1,051 | BDCBC61 |
| 0.69% | ASND | ASCENDIS PHARMA A/S | -- | $485,311.48 | 2,276 | BWXJHM8 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $485,062.56 | 7,167 | BK1KWG8 |
| 0.66% | AXSM | AXSOME THERAPEUTICS INC | -- | $464,259.60 | 1,890 | BYZR4X4 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $455,609.22 | 6,109 | BDJ0LS6 |
| 0.58% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $411,740.10 | 7,110 | 2437071 |
| 0.58% | SMMT | SUMMIT THERAPEUTICS INC | -- | $409,608.56 | 28,664 | BMTVQS7 |
| 0.57% | SNY | SANOFI-ADR | -- | $404,672.31 | 9,047 | 2964557 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $403,925.83 | 847 | BD59BS7 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $379,702.74 | 5,178 | BYQBFJ8 |
| 0.52% | BNTX | BIONTECH SE-ADR | -- | $364,424.50 | 4,213 | BK6H543 |
| 0.47% | KRYS | KRYSTAL BIOTECH INC | -- | $334,530.00 | 1,080 | BD6JX35 |
| 0.47% | NUVL | NUVALENT INC-A | -- | $333,391.25 | 2,705 | BMVBZD3 |
| 0.45% | ONC | BEONE MEDICINES LTD-ADR | -- | $316,708.77 | 1,181 | BYYWPW6 |
| 0.44% | TEM | TEMPUS AI INC-CL A | -- | $313,619.68 | 6,424 | BSLSJJ0 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $311,938.72 | 4,364 | 2975098 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $311,652.85 | 4,553 | BBBSBJ5 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $275,558.00 | 38,008 | BNSP0B8 |
| 0.39% | ALKS | ALKERMES PLC | -- | $272,959.27 | 6,163 | B3P6D26 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $257,589.57 | 1,029 | BQ721R4 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $249,959.07 | 2,361 | BDCBCD8 |
| 0.35% | PCVX | VAXCYTE INC | -- | $249,448.48 | 5,321 | BKPVGH6 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $237,802.03 | 7,523 | BJRFSB7 |
| 0.33% | ABVX | ABIVAX SA-ADR | -- | $233,277.12 | 2,271 | BLC89B2 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $232,037.47 | 3,017 | BMPRZV5 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $225,608.16 | 3,062 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $222,058.20 | 2,905 | BQBBDY8 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $221,934.36 | 2,526 | BF2YWG4 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $213,015.88 | 2,231 | BJDX8Y8 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $191,943.96 | 6,002 | BLR6XK8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $182,754.00 | 3,550 | BDHF4K6 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $179,054.08 | 736 | 2501578 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $176,980.41 | 3,123 | BRBCSP4 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $176,914.24 | 4,624 | BTZRLN8 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $176,909.76 | 10,431 | BT18HP9 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,858.48 | 4,423 | BLB0YQ9 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $172,380.00 | 2,028 | BM9HHL5 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $171,973.34 | 3,773 | BFZQ0L8 |
| 0.24% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $170,874.08 | 11,632 | BFNF1D6 |
| 0.23% | TVTX | TRAVERE THERAPEUTICS INC | -- | $165,575.13 | 3,409 | BLFGJD5 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $162,276.46 | 3,074 | BRJ3GY4 |
| 0.23% | TWST | TWIST BIOSCIENCE CORP | -- | $158,755.96 | 2,266 | BGKG6G7 |
| 0.22% | TNGX | TANGO THERAPEUTICS INC | -- | $157,105.68 | 4,978 | BP2P6L0 |
| 0.22% | ERAS | ERASCA INC | -- | $153,464.04 | 11,444 | BNLYBF3 |
| 0.21% | VCYT | VERACYTE INC | -- | $144,667.12 | 2,938 | BFTWZY0 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $137,657.52 | 6,303 | 2713317 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $135,403.84 | 3,872 | BDD19F8 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $135,081.96 | 3,966 | BKY5JZ8 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $133,097.09 | 4,351 | BKS3RS7 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $129,175.76 | 4,252 | BP8JSP4 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $121,891.77 | 5,863 | BD2B4V0 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $119,737.77 | 1,789 | BKVF0J2 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $118,800.00 | 2,880 | BQS9486 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $114,780.49 | 3,767 | BK6L288 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $109,079.04 | 6,087 | BN15WD1 |
| 0.15% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $104,555.78 | 3,122 | BMX9K07 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $104,537.73 | 4,587 | BKX9VD3 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $98,813.12 | 5,692 | BJ5FZ74 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $96,818.15 | 1,573 | BMH5RL1 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $96,799.20 | 2,120 | B72ZBG4 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $96,427.74 | 1,411 | BMGJZJ8 |
| 0.13% | ALMS | ALUMIS INC | -- | $93,526.74 | 4,674 | BPLQG36 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $93,078.54 | 6,606 | BN2R582 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $91,115.22 | 3,246 | BK0VHF6 |
| 0.12% | GRAL | GRAIL INC | -- | $87,635.10 | 1,439 | BSLSSX7 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,570.75 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $83,851.16 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $82,692.60 | 1,698 | BRXB0C0 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $81,383.09 | 3,571 | BJ62Z18 |
| 0.11% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $79,297.56 | 2,196 | BMFD115 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $77,542.92 | 4,914 | BFWLC09 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $77,227.43 | 9,271 | 2100362 |
| 0.11% | PHVS | PHARVARIS NV | -- | $74,797.20 | 2,367 | BMZ2X38 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,974.00 | 2,140 | BKSGZN7 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $72,563.16 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $71,496.60 | 8,805 | B9NSBM2 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $70,726.50 | 2,925 | BP9N0G0 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $70,040.30 | 2,255 | BFXC933 |
| 0.10% | VCEL | VERICEL CORP | -- | $69,431.25 | 1,875 | BSBMN89 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $68,175.03 | 8,049 | BNZB1X8 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,396.00 | 830 | BCDWBX6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $64,443.78 | 4,742 | BJH9ZN0 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $64,337.16 | 2,766 | BPCQZY9 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $63,221.76 | 1,764 | BR3T9B6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $62,136.34 | 19,297 | BM9FJ13 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $62,000.07 | 2,111 | BJQ05Z6 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,759.60 | 2,740 | BDDXF67 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $61,573.75 | 3,875 | B8DPDT7 |
| 0.09% | QURE | UNIQURE NV | -- | $60,990.30 | 2,305 | BJFSR88 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $60,951.24 | 2,166 | BCBVTX1 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $59,712.90 | 2,379 | BBC9WC7 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $59,463.28 | 3,802 | BMVLGP2 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,407.70 | 11,209 | BL53SR3 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $59,100.16 | 15,232 | BF0DMK7 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $58,320.40 | 3,455 | BRXYZ57 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $57,687.09 | 3,261 | BN7Q7R7 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $56,316.41 | 4,369 | BYZM6C2 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $55,622.19 | 1,651 | BQKXDX4 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $54,999.45 | 4,059 | BPCK358 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $54,286.08 | 10,128 | BNC1BX1 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $52,817.49 | 1,023 | BDRW1L7 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $52,238.81 | 13,429 | BWJDYK1 |
| 0.07% | NVAX | NOVAVAX INC | -- | $52,219.41 | 6,023 | BJDQXG4 |
| 0.07% | SEPN | SEPTERNA INC | -- | $51,383.57 | 1,657 | BQNKXX2 |
| 0.07% | TYRA | TYRA BIOSCIENCES INC | -- | $51,205.56 | 1,974 | BMVNDH9 |
| 0.07% | ALVO | ALVOTECH SA | -- | $50,793.60 | 12,210 | BPNTJ34 |
| 0.07% | ARDX | ARDELYX INC | -- | $50,769.60 | 9,066 | BN89V40 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,471.30 | 1,870 | BD06CS0 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $49,524.46 | 1,658 | BQXJKH2 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $49,443.10 | 5,810 | BK4PZ38 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $48,751.40 | 1,730 | BZ7PJQ1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $48,526.80 | 13,080 | BKM5C84 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $48,172.08 | 2,343 | BQB42F1 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $47,846.70 | 537 | BNSP8K3 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $46,806.98 | 2,818 | BP7KZP7 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $46,682.90 | 2,294 | BP6C0S2 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,649.85 | 1,527 | BMGTLY5 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $46,230.92 | 1,621 | BLCD809 |
| 0.07% | HROW | HARROW INC | -- | $45,840.20 | 1,370 | BHNDW86 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $42,547.54 | 1,778 | BSRK699 |
| 0.06% | MNKD | MANNKIND CORP | -- | $40,658.73 | 11,389 | BF081J4 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,316.80 | 1,172 | BX7RSN3 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $40,228.80 | 6,960 | BYZG9R0 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $39,871.00 | 6,134 | BLR7H87 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $39,263.62 | 3,487 | BMC3HS7 |
| 0.05% | ABSI | ABSCI CORP | -- | $37,981.63 | 5,561 | BN94K69 |
| 0.05% | PSNL | PERSONALIS INC | -- | $37,722.75 | 3,869 | BJQ0608 |
| 0.05% | SVRA | SAVARA INC | -- | $37,093.32 | 7,524 | BYXGN81 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $36,526.86 | 1,983 | BQB42H3 |
| 0.05% | EYPT | EYEPOINT INC | -- | $36,039.74 | 3,062 | BMGS7L1 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,698.95 | 1,495 | B3X26D8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,402.96 | 3,656 | BMCR7V2 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $34,113.18 | 3,054 | BYP80F1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $33,808.32 | 1,677 | BNFWZS4 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,103.40 | 4,510 | B8K7T65 |
| 0.05% | XNCR | XENCOR INC | -- | $32,233.79 | 2,711 | BGCYWN8 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $30,952.90 | 2,962 | BMZ4LN0 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,918.75 | 1,875 | BMNDK09 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,658.62 | 2,251 | BMFX8Y7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,285.76 | 992 | BGL0JK3 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,217.50 | 7,110 | BZ0QMB7 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $29,688.00 | 3,711 | BKVDFF7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $28,798.30 | 2,185 | BM90J52 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,595.84 | 2,912 | BJLKVS6 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $28,453.78 | 2,083 | BLFBZ32 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,350.58 | 3,218 | BYZD465 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $28,209.72 | 3,053 | BDDVW37 |
| 0.04% | ANNX | ANNEXON INC | -- | $27,814.80 | 5,349 | BMVV9R5 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $27,774.18 | 9,849 | BMFJJ97 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,748.18 | 8,837 | BBNBTD2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $27,617.52 | 1,934 | BQS7491 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,591.00 | 5,410 | BMCWKZ2 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,399.75 | 2,975 | BFYQFJ2 |
| 0.04% | GERN | GERON CORP | -- | $26,434.24 | 23,602 | 2370381 |
| 0.04% | OMER | OMEROS CORP | -- | $26,141.34 | 2,622 | B4NB858 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $25,343.20 | 1,604 | BT9K6D8 |
| 0.04% | CRMD | CORMEDIX INC | -- | $25,180.15 | 2,911 | BJ0LT31 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,911.95 | 763 | BL95N25 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,469.69 | 2,707 | BP0TQC5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,188.00 | 1,100 | BKLCWZ3 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,207.75 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,128.85 | 1,269 | BD9GVY0 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,643.84 | 672 | BQD3J33 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $20,398.08 | 1,536 | BRJJYT3 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,792.08 | 693 | BPBPCG8 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $19,410.16 | 6,028 | B3MZ6K5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,218.24 | 6,673 | BPBJFM7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,173.70 | 4,459 | BYV2W40 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $18,921.60 | 2,880 | BQHN6C7 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,669.70 | 6,265 | BYWVTY5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,998.89 | 4,511 | BYVQJ96 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $17,398.55 | 1,885 | BKLXFX5 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,037.23 | 2,363 | BDZ30Q0 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,846.83 | 1,989 | B91XRN2 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,579.20 | 2,112 | BSMLR16 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,450.51 | 571 | BS2F741 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,337.31 | 1,023 | BS2CR64 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,059.90 | 2,397 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,491.96 | 548 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,450.16 | 2,134 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,293.31 | 11,163 | B4N8MH9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,120.56 | 8,308 | BFZNYB7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $14,916.15 | 2,349 | BP81R42 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,049.00 | 4,014 | BMXNGZ6 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,378.32 | 2,186 | B12W3P6 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $13,359.93 | 1,997 | BRCFFK6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,246.95 | 1,879 | B7F2TY6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,920.22 | 3,609 | BKX9NQ0 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,847.32 | 1,124 | BPRBTY7 |
| 0.02% | OABI | OMNIAB INC | -- | $12,772.80 | 5,322 | BN13S71 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,596.04 | 2,889 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,318.46 | 4,631 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,167.20 | 1,072 | B9L5200 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,874.82 | 1,873 | BZ0G875 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,615.94 | 2,646 | 2107437 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,453.54 | 3,557 | BK5MWR1 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,435.28 | 2,697 | BQ6C357 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,328.75 | 1,125 | BM7V485 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,824.44 | 7,414 | BFMLGR4 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,634.45 | 4,013 | BDFKQ07 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,433.36 | 1,736 | BL5B6Z1 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,190.40 | 6,176 | BN4JN37 |
| 0.01% | IVVD | INVIVYD INC | -- | $10,141.56 | 10,244 | BM8NHS1 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,994.90 | 787 | BTNMG41 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,919.04 | 7,136 | BMYTJP4 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,619.61 | 2,387 | BMVBZF5 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,569.15 | 3,611 | BZ8FPH3 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,019.92 | 1,416 | BP81RK8 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,835.26 | 1,981 | BP7L561 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,702.04 | 3,426 | BYTYP72 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,673.28 | 2,464 | BJDX8Z9 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,418.67 | 2,089 | BPRB2N7 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,409.46 | 3,721 | BZC0D70 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,378.55 | 2,165 | BMF7DT9 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,252.27 | 3,341 | B5LL2C2 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,862.82 | 1,158 | BQV0J03 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,850.42 | 1,387 | 2517058 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,845.50 | 5,525 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,532.32 | 1,052 | BKC9SX3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,478.44 | 1,147 | BP2NYN2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,473.97 | 2,179 | BY7RB53 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,136.73 | 7,230 | BNR5QT9 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,134.87 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,600.09 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,355.36 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,688.52 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,964.83 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,999.50 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,915.10 | 2,303 | BLBR8D5 |
| -- | PEPG | PEPGEN INC | -- | $3,506.58 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,926.81 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,878.32 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,368.80 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 32.26% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 22,752,351 | -- | 3,874 | -- |
| 29.35% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,696,769 | -- | 3,524 | -- |
| 25.61% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,059,752 | -- | 3,075 | -- |
| 21.98% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,499,085 | -- | 2,639 | -- |
| 20.93% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,759,075 | -- | 2,513 | -- |
| 5.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,717,666 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,004,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $19,991,270.54 | 19,991,271 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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