BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 1/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.27% | 16.53% | 65.39% | 4.27% | 51.38% | 11.58% | -2.47% | 6.91% | 16.64% | 04/07/2010 |
| BIB Market Price | 4.19% | 16.41% | 65.44% | 4.19% | 51.07% | 11.50% | -2.49% | 6.94% | 16.64% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/11/2026- NAV $84.92
- NAV Change $+0.72
- Market Price $84.87
- Market Price Change $+0.75
- Trading Volume (M) 6,255
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 2/11/2026- NAV $84.92
- NAV Change $+0.72
- Market Price $84.87
- Market Price Change $+0.75
- Trading Volume (M) 6,255
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 2/10/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.74% | GILD | GILEAD SCIENCES INC | -- | $5,957,367.49 | 40,463 | 2369174 |
| 6.16% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,442,645.64 | 11,743 | 2931034 |
| 6.08% | AMGN | AMGEN INC | -- | $5,374,576.35 | 14,739 | 2023607 |
| 4.13% | REGN | REGENERON PHARMACEUTICALS | -- | $3,650,744.76 | 4,836 | 2730190 |
| 2.26% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,997,954.28 | 6,186 | B00FWN1 |
| 1.68% | INSM | INSMED INC | -- | $1,483,420.30 | 9,986 | 2614487 |
| 1.47% | BIIB | BIOGEN INC | -- | $1,298,172.31 | 6,869 | 2455965 |
| 1.28% | ARGX | ARGENX SE - ADR | -- | $1,135,597.08 | 1,363 | BDVLM39 |
| 1.08% | UTHR | UNITED THERAPEUTICS CORP | -- | $953,971.20 | 2,016 | 2430412 |
| 1.04% | INCY | INCYTE CORP | -- | $919,659.60 | 9,192 | 2471950 |
| 1.01% | ROIV | ROIVANT SCIENCES LTD | -- | $890,625.40 | 32,564 | BMW4NZ9 |
| 1.00% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $884,421.05 | 20,005 | BMVP7Y0 |
| 0.98% | RVMD | REVOLUTION MEDICINES INC | -- | $868,810.96 | 9,052 | BL71K91 |
| 0.97% | VTRS | VIATRIS INC | -- | $860,151.60 | 53,928 | BMWS3X9 |
| 0.97% | ILMN | ILLUMINA INC | -- | $853,615.28 | 7,154 | 2613990 |
| 0.87% | MRNA | MODERNA INC | -- | $768,172.54 | 18,292 | BGSXTS3 |
| 0.74% | BBIO | BRIDGEBIO PHARMA INC | -- | $653,824.34 | 9,022 | BK1KWG8 |
| 0.73% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $644,546.25 | 2,875 | BV9G6B8 |
| 0.73% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $642,550.20 | 4,668 | 2623911 |
| 0.72% | IONS | IONIS PHARMACEUTICALS INC | -- | $639,255.36 | 7,584 | BDJ0LS6 |
| 0.72% | GH | GUARDANT HEALTH INC | -- | $636,271.74 | 6,058 | BFXC911 |
| 0.68% | SNY | SANOFI-ADR | -- | $602,525.70 | 12,390 | 2964557 |
| 0.67% | MEDP | MEDPACE HOLDINGS INC | -- | $588,339.95 | 1,319 | BDCBC61 |
| 0.61% | EXEL | EXELIXIS INC | -- | $539,570.92 | 12,554 | 2576941 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $536,641.70 | 8,995 | 2437071 |
| 0.60% | SMMT | SUMMIT THERAPEUTICS INC | -- | $531,554.00 | 34,856 | BMTVQS7 |
| 0.59% | ONC | BEONE MEDICINES LTD-ADR | -- | $520,955.82 | 1,474 | BYYWPW6 |
| 0.58% | BNTX | BIONTECH SE-ADR | -- | $515,674.62 | 4,734 | BK6H543 |
| 0.58% | RNA | AVIDITY BIOSCIENCES INC | -- | $514,238.95 | 7,055 | BMWHPY1 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $508,996.29 | 1,063 | BD59BS7 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $471,217.35 | 2,845 | B4Q5ZN4 |
| 0.51% | TEM | TEMPUS AI INC | -- | $452,292.72 | 8,094 | BSLSJJ0 |
| 0.50% | HALO | HALOZYME THERAPEUTICS INC | -- | $441,691.32 | 5,506 | 2975098 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $434,948.00 | 2,360 | BYZR4X4 |
| 0.45% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $400,108.28 | 6,359 | BYQBFJ8 |
| 0.42% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $375,282.08 | 1,171 | BQ721R4 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $371,266.25 | 5,725 | BBBSBJ5 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $367,610.60 | 1,358 | BD6JX35 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $345,234.56 | 3,382 | BMVBZD3 |
| 0.38% | PCVX | VAXCYTE INC | -- | $336,972.42 | 6,129 | BKPVGH6 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $329,413.52 | 2,764 | BLC89B2 |
| 0.36% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $321,468.75 | 3,125 | BF2YWG4 |
| 0.34% | IBRX | IMMUNITYBIO INC | -- | $302,534.08 | 46,118 | BNSP0B8 |
| 0.33% | CAI | CARIS LIFE SCIENCES INC | -- | $292,887.87 | 13,211 | BT18HP9 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $271,452.99 | 7,187 | BLR6XK8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $271,174.26 | 3,759 | B17VCN9 |
| 0.30% | ALKS | ALKERMES PLC | -- | $268,420.32 | 7,731 | B3P6D26 |
| 0.30% | KYMR | KYMERA THERAPEUTICS INC | -- | $267,801.81 | 3,369 | BMPRZV5 |
| 0.28% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $245,782.95 | 3,129 | BQS9486 |
| 0.28% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $245,516.76 | 2,927 | BDCBCD8 |
| 0.27% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $242,789.46 | 2,406 | BJDX8Y8 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $227,528.64 | 4,776 | BFZQ0L8 |
| 0.25% | IMVT | IMMUNOVANT INC | -- | $218,962.76 | 8,207 | BJRFSB7 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $217,879.46 | 4,462 | BDHF4K6 |
| 0.25% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $217,252.44 | 14,719 | BFNF1D6 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $211,531.23 | 4,443 | BDD19F8 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $206,577.80 | 14,446 | B19FQ48 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $200,520.93 | 3,777 | BRBCSP4 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $195,540.24 | 5,844 | BTZRLN8 |
| 0.21% | GRAL | GRAIL INC | -- | $189,216.00 | 1,825 | BSLSSX7 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $185,231.01 | 5,309 | BP8JSP4 |
| 0.21% | ACLX | ARCELLX INC | -- | $182,018.68 | 2,707 | BPCJ1Q2 |
| 0.21% | ADMA | ADMA BIOLOGICS INC | -- | $181,424.32 | 11,144 | B9NSBM2 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $179,806.70 | 7,921 | 2713317 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $172,432.44 | 922 | 2501578 |
| 0.19% | APGE | APOGEE THERAPEUTICS INC | -- | $168,138.50 | 2,567 | BM9HHL5 |
| 0.18% | TERN | TERNS PHARMACEUTICALS INC | -- | $161,085.42 | 4,218 | BMDJ0C9 |
| 0.18% | ERAS | ERASCA INC | -- | $158,743.80 | 13,284 | BNLYBF3 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $154,235.34 | 3,618 | BRJ3GY4 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $154,156.80 | 5,735 | BKX9VD3 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $153,667.00 | 4,957 | BKY5JZ8 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $140,458.78 | 2,863 | BGKG6G7 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $137,418.30 | 2,685 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $137,048.03 | 3,701 | BFTWZY0 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $136,491.25 | 4,105 | BK0VHF6 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $136,103.94 | 6,867 | BD2B4V0 |
| 0.15% | APLS | APELLIS PHARMACEUTICALS INC | -- | $133,696.18 | 5,921 | BYTQ6X1 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $132,158.00 | 1,768 | BMGJZJ8 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $131,753.55 | 2,991 | BL55460 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $131,029.08 | 1,988 | BMH5RL1 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $128,039.45 | 4,751 | BK6L288 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $127,010.48 | 4,189 | BLFGJD5 |
| 0.14% | SYRE | SPYRE THERAPEUTICS INC | -- | $121,923.48 | 3,633 | BQBBDY8 |
| 0.14% | ALMS | ALUMIS INC | -- | $121,037.68 | 4,552 | BPLQG36 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $115,114.35 | 3,705 | BP9N0G0 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $114,615.18 | 6,687 | BN15WD1 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $111,794.72 | 7,148 | BJ5FZ74 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $109,311.40 | 4,517 | BJ62Z18 |
| 0.12% | MAZE | MAZE THERAPEUTICS INC | -- | $108,977.61 | 2,253 | BSRK699 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $106,423.29 | 7,831 | BYZG9R0 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $106,375.35 | 4,517 | BLB0YQ9 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $104,444.10 | 5,454 | BKS3RS7 |
| 0.12% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $102,297.21 | 2,697 | BKSGZN7 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,561.65 | 2,115 | BRXB0C0 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $92,688.75 | 24,075 | BM9FJ13 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $90,074.25 | 9,975 | BNZB1X8 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $89,926.98 | 4,906 | B8DPDT7 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,878.88 | 6,173 | BFWLC09 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $86,777.00 | 2,675 | BJQ05Z6 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $86,772.40 | 4,070 | BN7Q7R7 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $86,071.71 | 3,683 | BMZ4LN0 |
| 0.10% | VCEL | VERICEL CORP | -- | $84,277.12 | 2,368 | BSBMN89 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $84,065.32 | 1,052 | BCDWBX6 |
| 0.09% | MNKD | MANNKIND CORP | -- | $83,823.74 | 14,378 | BF081J4 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $83,752.20 | 2,737 | BBC9WC7 |
| 0.09% | ARDX | ARDELYX INC | -- | $83,052.10 | 11,377 | BN89V40 |
| 0.09% | HROW | HARROW INC | -- | $82,729.14 | 1,734 | BHNDW86 |
| 0.09% | PHVS | PHARVARIS NV | -- | $82,412.52 | 2,999 | BMZ2X38 |
| 0.09% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $80,110.44 | 4,612 | BV2DHY6 |
| 0.09% | TNGX | TANGO THERAPEUTICS INC | -- | $80,023.14 | 6,306 | BP2P6L0 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $79,645.92 | 3,504 | BPCQZY9 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $79,451.35 | 2,090 | BQKXDX4 |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $79,203.36 | 2,102 | BQXJKH2 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $78,468.60 | 2,499 | BMVNDH9 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $78,071.70 | 4,746 | BMVLGP2 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $77,617.47 | 2,779 | BMFD115 |
| 0.09% | PGEN | PRECIGEN INC | -- | $77,202.22 | 16,567 | BKM5C84 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $76,564.38 | 5,142 | BPCK358 |
| 0.09% | INVA | INNOVIVA INC | -- | $76,461.84 | 3,501 | BDDXF67 |
| 0.09% | ALVO | ALVOTECH SA | -- | $76,211.20 | 14,656 | BPNTJ34 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,888.78 | 1,297 | BTJZB49 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $74,538.96 | 2,267 | BKVF0J2 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,064.90 | 2,730 | BCBVTX1 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $72,953.85 | 8,115 | BN2R582 |
| 0.08% | QURE | UNIQURE NV | -- | $72,079.07 | 2,917 | BJFSR88 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $70,601.22 | 3,942 | BMX9K07 |
| 0.08% | UPB | UPSTREAM BIO INC | -- | $70,359.30 | 2,530 | BRCFFK6 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $69,190.00 | 1,480 | BX7RSN3 |
| 0.08% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $68,471.26 | 3,497 | BYP80F1 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $67,545.00 | 6,004 | BJH9ZN0 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $67,051.26 | 2,043 | BLCD809 |
| 0.08% | NVAX | NOVAVAX INC | -- | $66,578.75 | 7,609 | BJDQXG4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $65,469.25 | 17,005 | BWJDYK1 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $65,111.04 | 1,296 | BDRW1L7 |
| 0.07% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,587.93 | 5,423 | BYZM6C2 |
| 0.07% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $64,569.90 | 9,858 | 2100362 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $63,054.00 | 2,232 | BR3T9B6 |
| 0.07% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $61,482.64 | 2,152 | BNFWZS4 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,668.93 | 3,049 | BP7KZP7 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $59,136.42 | 4,326 | BRXYZ57 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $57,926.88 | 2,484 | BFXC933 |
| 0.06% | TSHA | TAYSHA GENE THERAPIES INC | -- | $57,456.00 | 12,825 | BNC1BX1 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $56,727.30 | 681 | BNSP8K3 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $56,092.18 | 7,769 | BLR7H87 |
| 0.06% | SEPN | SEPTERNA INC | -- | $55,963.20 | 2,096 | BQNKXX2 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $54,895.94 | 4,807 | BLB0YH0 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $54,894.21 | 5,243 | BYSS4X4 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $53,979.24 | 2,513 | BQB42H3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $53,178.72 | 3,876 | BMGS7L1 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $52,664.64 | 5,712 | B8K7T65 |
| 0.06% | SVRA | SAVARA INC | -- | $50,207.29 | 9,527 | BYXGN81 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,618.66 | 959 | BL95N25 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $48,920.14 | 6,514 | BK4PZ38 |
| 0.05% | GERN | GERON CORP | -- | $48,420.18 | 29,889 | 2370381 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $48,326.20 | 18,587 | BF0DMK7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $48,153.60 | 4,560 | BKVDFF7 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $48,141.92 | 12,472 | BMFJJ97 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $47,500.64 | 2,192 | BZ7PJQ1 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,640.36 | 3,341 | BMG99Y1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,036.20 | 2,373 | BMNDK09 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $45,909.76 | 4,628 | BMCR7V2 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $44,518.32 | 2,904 | BP6C0S2 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $44,287.40 | 14,015 | BL53SR3 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $44,249.79 | 1,367 | BKLCWZ3 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $43,869.49 | 7,933 | BYWVTY5 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,777.36 | 2,014 | B3X26D8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $42,703.42 | 3,331 | BJLKVS6 |
| 0.05% | XNCR | XENCOR INC | -- | $41,365.28 | 3,344 | BGCYWN8 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $41,305.04 | 2,296 | BQS7491 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $40,747.64 | 1,933 | BMGTLY5 |
| 0.05% | ARVN | ARVINAS INC | -- | $40,414.08 | 3,007 | BDZ30Q0 |
| 0.04% | BCAX | BICARA THERAPEUTICS INC | -- | $38,398.05 | 2,565 | BQB42F1 |
| 0.04% | ANNX | ANNEXON INC | -- | $38,018.97 | 6,777 | BMVV9R5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $37,944.27 | 11,193 | BBNBTD2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,460.80 | 9,005 | BZ0QMB7 |
| 0.04% | OMER | OMEROS CORP | -- | $37,084.40 | 3,320 | B4NB858 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $36,974.08 | 2,816 | BMFX8Y7 |
| 0.04% | PSNL | PERSONALIS INC | -- | $35,841.96 | 4,158 | BJQ0608 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $35,835.15 | 1,833 | BD9GVY0 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $35,528.67 | 2,367 | BD06CS0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $34,962.03 | 7,617 | B3MZ6K5 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $33,899.01 | 1,679 | BT9K6D8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,717.54 | 2,766 | BM90J52 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,940.16 | 4,074 | BYZD465 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $29,427.00 | 850 | BQD3J33 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,905.84 | 8,452 | BPBJFM7 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $28,649.40 | 3,673 | BDDVW37 |
| 0.03% | CRMD | CORMEDIX INC | -- | $28,368.41 | 3,689 | BJ0LT31 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,342.88 | 3,769 | BFYQFJ2 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $27,751.48 | 4,412 | BMC3HS7 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,283.41 | 2,667 | BMFK3H6 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $26,201.56 | 2,534 | BJDX8Z9 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $25,586.16 | 14,136 | B4N8MH9 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,280.64 | 3,648 | BQHN6C7 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $25,250.21 | 10,837 | BJ0CK86 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $24,455.90 | 1,426 | BM7V485 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $24,342.50 | 2,675 | BKLXFX5 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $24,055.68 | 3,417 | BQ6C357 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $23,544.03 | 993 | BTNMG41 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $23,390.77 | 7,823 | BN4JN37 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,970.61 | 677 | B292NQ7 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $22,719.90 | 4,886 | BFY7DC4 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,695.96 | 2,636 | BLFBZ32 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,580.36 | 2,701 | B2Q9833 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $22,579.20 | 2,520 | B91XRN2 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,431.57 | 3,353 | 2107437 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,048.32 | 5,712 | BYVQJ96 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,184.80 | 6,790 | BMCWKZ2 |
| 0.02% | IVVD | INVIVYD INC | -- | $21,149.25 | 12,975 | BM8NHS1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,974.50 | 2,370 | BZ0G875 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $20,531.14 | 2,767 | B12W3P6 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $20,011.90 | 1,465 | BQV0J03 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,367.80 | 1,790 | BP81RK8 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $19,103.76 | 1,256 | BGL0JK3 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $19,089.63 | 1,351 | B9L5200 |
| 0.02% | ABSI | ABSCI CORP | -- | $18,588.24 | 7,041 | BN94K69 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $18,516.45 | 5,073 | BYV2W40 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $18,439.80 | 876 | BPBPCG8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,782.18 | 10,522 | BFZNYB7 |
| 0.02% | PEPG | PEPGEN INC | -- | $17,736.69 | 3,219 | BMTX3D7 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,041.50 | 1,082 | BPRBTY7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,737.99 | 2,973 | BP81R42 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $16,648.56 | 4,868 | BKRRKY7 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $16,564.68 | 4,183 | BYTYP72 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,394.40 | 5,060 | BDFKQ07 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,100.35 | 2,051 | BSMLR16 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,592.99 | 2,359 | B7F2TY6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $15,217.28 | 3,658 | BLN9Z50 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,175.46 | 3,023 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $14,803.20 | 2,570 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $14,431.60 | 2,648 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,385.06 | 4,701 | BZC0D70 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,505.75 | 3,035 | BDRJH21 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,430.56 | 9,392 | BFMLGR4 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,346.64 | 4,008 | BMXNGZ6 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $12,944.52 | 1,754 | 2517058 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $12,849.59 | 1,019 | BTXQTX3 |
| 0.01% | NGNE | NEUROGENE INC | -- | $12,325.00 | 725 | BS2F741 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $12,194.58 | 2,166 | BKDQKM6 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,940.49 | 5,659 | BRK0149 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $11,718.20 | 4,507 | BK5MWR1 |
| 0.01% | OABI | OMNIAB INC | -- | $11,660.20 | 6,740 | BN13S71 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $11,025.48 | 2,644 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,959.21 | 789 | BRJJYT3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,208.30 | 2,759 | BY7RB53 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,071.60 | 9,156 | BNR5QT9 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,068.10 | 1,330 | BKC9SX3 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,851.52 | 2,199 | BL5B6Z1 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,206.40 | 8,768 | BMYTJP4 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $8,349.92 | 4,538 | BKX9NQ0 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,189.28 | 1,452 | BP2NYN2 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,136.38 | 4,571 | BZ8FPH3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,870.32 | 4,376 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,158.84 | 7,796 | BNNXX52 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,119.78 | 4,567 | BNNXX18 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,083.04 | 2,668 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,767.20 | 3,560 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $5,286.25 | 4,229 | B5LL2C2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $5,237.54 | 2,506 | BP7L561 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $4,051.85 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $15.64 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 39.21% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 34,665,505 | -- | 5,878 | -- |
| 29.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,037,463 | -- | 4,415 | -- |
| 23.09% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,411,248 | -- | 3,461 | -- |
| 17.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,563,503 | -- | 2,639 | -- |
| 16.57% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,649,390 | -- | 2,484 | -- |
| 4.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,733,118 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,654,843.29 | 26,654,843 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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