BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,952,792
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/18/2026- NAV
- NAV Change
- Market Price $85.02
- Market Price Change $+0.07
- Trading Volume (M) 11,468
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,952,792
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/18/2026- NAV
- NAV Change
- Market Price $85.02
- Market Price Change $+0.07
- Trading Volume (M) 11,468
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/18/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.07% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,746,270.85 | 8,295 | 2931034 |
| 5.03% | AMGN | AMGEN INC | -- | $3,721,027.20 | 11,022 | 2023607 |
| 4.62% | GILD | GILEAD SCIENCES INC | -- | $3,417,261.12 | 27,612 | 2369174 |
| 3.01% | REGN | REGENERON PHARMACEUTICALS | -- | $2,224,451.18 | 3,647 | 2730190 |
| 1.78% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,314,531.43 | 4,727 | B00FWN1 |
| 1.66% | RVMD | REVOLUTION MEDICINES INC | -- | $1,226,662.74 | 7,526 | BL71K91 |
| 1.39% | BIIB | BIOGEN INC | -- | $1,027,327.08 | 5,226 | 2455965 |
| 1.22% | MRNA | MODERNA INC | -- | $898,829.88 | 14,053 | BGSXTS3 |
| 1.17% | ILMN | ILLUMINA INC | -- | $867,297.08 | 5,356 | 2613990 |
| 1.16% | ARGX | ARGENX SE - ADR | -- | $857,532.44 | 977 | BDVLM39 |
| 1.12% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $831,366.08 | 15,698 | BMVP7Y0 |
| 1.09% | UTHR | UNITED THERAPEUTICS CORP | -- | $806,494.77 | 1,503 | 2430412 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $800,302.09 | 25,463 | BMW4NZ9 |
| 0.99% | INSM | INSMED INC | -- | $735,073.40 | 7,673 | 2614487 |
| 0.94% | INCY | INCYTE CORP | -- | $694,611.84 | 7,072 | 2471950 |
| 0.86% | VTRS | VIATRIS INC | -- | $633,643.62 | 41,226 | BMWS3X9 |
| 0.84% | GH | GUARDANT HEALTH INC | -- | $618,575.32 | 4,694 | BFXC911 |
| 0.76% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $563,512.40 | 3,560 | 2623911 |
| 0.68% | ASND | ASCENDIS PHARMA A/S | -- | $502,978.57 | 2,179 | BWXJHM8 |
| 0.67% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $498,969.86 | 2,221 | B4Q5ZN4 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $465,262.20 | 1,011 | BDCBC61 |
| 0.62% | EXEL | EXELIXIS INC | -- | $461,895.18 | 8,898 | 2576941 |
| 0.62% | BBIO | BRIDGEBIO PHARMA INC | -- | $459,516.18 | 6,934 | BK1KWG8 |
| 0.62% | AXSM | AXSOME THERAPEUTICS INC | -- | $455,910.00 | 1,820 | BYZR4X4 |
| 0.59% | IONS | IONIS PHARMACEUTICALS INC | -- | $433,602.00 | 5,850 | BDJ0LS6 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $412,692.00 | 816 | BD59BS7 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $407,954.52 | 4,986 | BYQBFJ8 |
| 0.51% | CYTK | CYTOKINETICS INC | -- | $378,065.22 | 4,799 | BBBSBJ5 |
| 0.51% | SMMT | SUMMIT THERAPEUTICS INC | -- | $377,808.75 | 27,477 | BMTVQS7 |
| 0.51% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $374,134.29 | 6,841 | 2437071 |
| 0.51% | BNTX | BIONTECH SE-ADR | -- | $373,921.46 | 4,114 | BK6H543 |
| 0.49% | KRYS | KRYSTAL BIOTECH INC | -- | $363,374.64 | 1,044 | BD6JX35 |
| 0.47% | SNY | SANOFI-ADR | -- | $349,084.06 | 8,237 | 2964557 |
| 0.43% | NUVL | NUVALENT INC-A | -- | $321,411.72 | 2,604 | BMVBZD3 |
| 0.43% | ONC | BEONE MEDICINES LTD-ADR | -- | $315,805.35 | 1,169 | BYYWPW6 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $314,089.52 | 6,178 | BSLSJJ0 |
| 0.39% | HALO | HALOZYME THERAPEUTICS INC | -- | $287,841.45 | 4,199 | 2975098 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $278,639.97 | 987 | BQ721R4 |
| 0.37% | IBRX | IMMUNITYBIO INC | -- | $272,886.72 | 37,077 | BNSP0B8 |
| 0.37% | SYRE | SPYRE THERAPEUTICS INC | -- | $271,733.84 | 3,076 | BQBBDY8 |
| 0.36% | ALKS | ALKERMES PLC | -- | $265,441.00 | 5,900 | B3P6D26 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $263,332.16 | 2,912 | BMPRZV5 |
| 0.36% | PCVX | VAXCYTE INC | -- | $262,961.28 | 5,112 | BKPVGH6 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $256,982.22 | 2,277 | BDCBCD8 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $256,851.12 | 7,268 | BJRFSB7 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $235,006.12 | 2,428 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $231,885.28 | 2,936 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $231,293.67 | 2,159 | BJDX8Y8 |
| 0.28% | COGT | COGENT BIOSCIENCES INC | -- | $208,932.46 | 6,049 | BLR6XK8 |
| 0.28% | ABVX | ABIVAX SA-ADR | -- | $203,455.80 | 2,052 | BLC89B2 |
| 0.27% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $200,773.86 | 4,242 | BFZQ0L8 |
| 0.27% | APGE | APOGEE THERAPEUTICS INC | -- | $198,022.58 | 2,191 | BM9HHL5 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $194,889.92 | 709 | 2501578 |
| 0.26% | TWST | TWIST BIOSCIENCE CORP | -- | $192,982.24 | 2,204 | BGKG6G7 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $190,691.76 | 3,122 | BRBCSP4 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $184,829.29 | 10,007 | BT18HP9 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,663.26 | 3,414 | BDHF4K6 |
| 0.25% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $183,075.74 | 11,294 | BFNF1D6 |
| 0.25% | TVTX | TRAVERE THERAPEUTICS INC | -- | $181,553.80 | 3,292 | BLFGJD5 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $181,058.02 | 3,422 | BRJ3GY4 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $177,288.60 | 4,430 | BLB0YQ9 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $165,302.80 | 4,316 | BTZRLN8 |
| 0.21% | ORKA | ORUKA THERAPEUTICS INC | -- | $154,445.90 | 2,135 | BKVF0J2 |
| 0.20% | VCYT | VERACYTE INC | -- | $151,504.75 | 2,825 | BFTWZY0 |
| 0.20% | ERAS | ERASCA INC | -- | $150,493.03 | 11,009 | BNLYBF3 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $144,163.74 | 4,148 | BKS3RS7 |
| 0.19% | TNGX | TANGO THERAPEUTICS INC | -- | $143,234.37 | 5,121 | BP2P6L0 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $140,209.29 | 3,809 | BKY5JZ8 |
| 0.18% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $133,902.71 | 3,733 | BDD19F8 |
| 0.18% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $131,060.44 | 6,062 | 2713317 |
| 0.18% | DNLI | DENALI THERAPEUTICS INC | -- | $130,955.58 | 5,618 | BD2B4V0 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $124,201.32 | 3,638 | BK6L288 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $123,436.54 | 4,138 | BP8JSP4 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $122,847.60 | 2,760 | BQS9486 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $120,592.72 | 7,594 | BN2R582 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $116,057.88 | 4,428 | BKX9VD3 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $115,869.60 | 5,852 | BN15WD1 |
| 0.14% | QURE | UNIQURE NV | -- | $103,458.15 | 2,235 | BJFSR88 |
| 0.14% | ALMS | ALUMIS INC | -- | $102,325.11 | 4,371 | BPLQG36 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $99,324.98 | 5,666 | BJ5FZ74 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $97,235.60 | 2,156 | BMFD115 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $97,125.30 | 3,110 | BK0VHF6 |
| 0.13% | GRAL | GRAIL INC | -- | $96,821.06 | 1,519 | BSLSSX7 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $96,192.68 | 1,523 | BMH5RL1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $95,708.08 | 1,352 | BMGJZJ8 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $95,683.28 | 3,487 | BJ62Z18 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $94,468.32 | 3,859 | BV2DHY6 |
| 0.12% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $91,200.90 | 2,055 | B72ZBG4 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $90,325.29 | 1,639 | BRXB0C0 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $89,163.69 | 2,541 | BL55460 |
| 0.12% | TRVI | TREVI THERAPEUTICS INC | -- | $86,497.46 | 5,026 | BJH9ZN0 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $83,371.05 | 2,985 | BMX9K07 |
| 0.11% | PHVS | PHARVARIS NV | -- | $81,114.40 | 2,473 | BMZ2X38 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $80,883.03 | 8,997 | 2100362 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $80,050.10 | 2,215 | BFXC933 |
| 0.10% | NTLA | INTELLIA THERAPEUTICS INC | -- | $77,456.81 | 4,943 | BYZM6C2 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $74,843.62 | 4,547 | BFWLC09 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $73,091.93 | 7,751 | BNZB1X8 |
| 0.10% | VCEL | VERICEL CORP | -- | $72,500.80 | 1,808 | BSBMN89 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $72,333.43 | 1,681 | BQXJKH2 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $71,919.60 | 2,920 | BP9N0G0 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $71,906.80 | 2,105 | BCBVTX1 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $68,355.00 | 2,205 | BJQ05Z6 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,190.72 | 2,049 | BKSGZN7 |
| 0.09% | ADMA | ADMA BIOLOGICS INC | -- | $68,183.55 | 8,205 | B9NSBM2 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $67,875.22 | 2,686 | BBC9WC7 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,474.55 | 3,735 | B8DPDT7 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $65,310.66 | 10,173 | BNC1BX1 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $64,197.90 | 3,658 | BMVLGP2 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $63,989.45 | 805 | BCDWBX6 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $63,216.62 | 1,693 | BR3T9B6 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $61,801.46 | 15,806 | BF0DMK7 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $61,677.12 | 3,936 | BPCK358 |
| 0.08% | PGEN | PRECIGEN INC | -- | $60,833.22 | 12,621 | BKM5C84 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $59,994.02 | 18,574 | BM9FJ13 |
| 0.08% | ZYME | ZYMEWORKS INC | -- | $59,793.76 | 2,584 | BPCQZY9 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $59,779.30 | 10,810 | BL53SR3 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $59,613.60 | 2,105 | BMVNDH9 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $59,605.40 | 1,598 | BQKXDX4 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $59,603.00 | 3,137 | BN7Q7R7 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $59,292.81 | 1,031 | BDRW1L7 |
| 0.08% | CMPS | COMPASS PATHWAYS PLC | -- | $59,041.36 | 4,712 | BMC3HS7 |
| 0.08% | INVA | INNOVIVA INC | -- | $58,766.37 | 2,613 | BDDXF67 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $58,548.00 | 4,100 | BYSS4X4 |
| 0.08% | URGN | UROGEN PHARMA LTD | -- | $57,908.25 | 1,725 | BZ7PJQ1 |
| 0.08% | SEPN | SEPTERNA INC | -- | $57,727.32 | 1,596 | BQNKXX2 |
| 0.08% | HROW | HARROW INC | -- | $56,588.40 | 1,320 | BHNDW86 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,765.21 | 2,991 | BP7KZP7 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $54,685.20 | 5,970 | BK4PZ38 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $54,032.98 | 2,326 | BQB42F1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $53,865.28 | 2,422 | BP6C0S2 |
| 0.07% | NVAX | NOVAVAX INC | -- | $53,145.73 | 5,821 | BJDQXG4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $52,913.98 | 13,033 | BWJDYK1 |
| 0.07% | ARDX | ARDELYX INC | -- | $52,907.25 | 8,745 | BN89V40 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,339.26 | 1,649 | BMGTLY5 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $51,257.88 | 3,348 | BRXYZ57 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,307.12 | 1,959 | BSRK699 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $48,292.95 | 519 | BNSP8K3 |
| 0.06% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,016.40 | 1,574 | BLCD809 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $44,208.30 | 2,235 | BQB42H3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $43,304.24 | 11,047 | BPNTJ34 |
| 0.06% | MNKD | MANNKIND CORP | -- | $43,091.78 | 10,937 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,478.40 | 6,112 | BLR7H87 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $41,955.76 | 6,811 | BYZG9R0 |
| 0.06% | ABSI | ABSCI CORP | -- | $40,925.43 | 5,523 | BN94K69 |
| 0.05% | EYPT | EYEPOINT INC | -- | $40,305.44 | 2,968 | BMGS7L1 |
| 0.05% | SVRA | SAVARA INC | -- | $39,902.50 | 7,255 | BYXGN81 |
| 0.05% | PSNL | PERSONALIS INC | -- | $39,071.78 | 3,707 | BJQ0608 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $38,503.92 | 1,148 | BX7RSN3 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $37,106.96 | 3,278 | BFYQFJ2 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,456.07 | 2,977 | BYP80F1 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,919.75 | 3,515 | BMCR7V2 |
| 0.04% | XNCR | XENCOR INC | -- | $33,180.00 | 2,625 | BGCYWN8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $32,705.28 | 2,176 | BM90J52 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,691.98 | 1,574 | BT9K6D8 |
| 0.04% | GRFS | GRIFOLS SA-ADR | -- | $31,960.60 | 4,319 | B8K7T65 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,818.15 | 6,993 | BZ0QMB7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,505.60 | 970 | BGL0JK3 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,209.99 | 3,143 | BYZD465 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,115.85 | 3,665 | BKVDFF7 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $31,105.69 | 1,393 | B3X26D8 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,033.80 | 9,852 | BMFJJ97 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $30,714.24 | 2,823 | BJLKVS6 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,700.98 | 2,159 | BMFX8Y7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,258.50 | 1,825 | BMNDK09 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $29,785.37 | 2,923 | BDDVW37 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $29,471.49 | 3,099 | BMZ4LN0 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $29,362.41 | 1,561 | BNFWZS4 |
| 0.04% | SLDB | SOLID BIOSCIENCES INC | -- | $29,030.05 | 3,485 | BQHN6C7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $28,705.95 | 9,113 | BBNBTD2 |
| 0.04% | GERN | GERON CORP | -- | $28,614.60 | 22,710 | 2370381 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,420.00 | 5,800 | BMVV9R5 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $27,820.80 | 1,920 | BRJJYT3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,504.84 | 2,211 | BMFK3H6 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,154.40 | 5,222 | BMCWKZ2 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,999.70 | 2,093 | BLFBZ32 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,598.87 | 1,851 | BQS7491 |
| 0.04% | OMER | OMEROS CORP | -- | $26,337.36 | 2,562 | B4NB858 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $24,438.00 | 12,219 | BFZNYB7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,076.59 | 2,777 | BJ0LT31 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,760.10 | 746 | BL95N25 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $23,204.40 | 3,660 | BP81R42 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,767.36 | 1,078 | BKLCWZ3 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $22,735.65 | 7,707 | BYWVTY5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,248.00 | 4,944 | BYV2W40 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,556.14 | 2,594 | BP0TQC5 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,556.05 | 655 | BQD3J33 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $21,513.70 | 1,235 | BS2CR64 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,197.88 | 1,166 | BD9GVY0 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,917.11 | 4,441 | BYVQJ96 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $20,652.62 | 6,394 | BPBJFM7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $20,627.58 | 5,827 | B3MZ6K5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,053.36 | 668 | BPBPCG8 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $18,657.00 | 6,910 | BFY7DC4 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $17,880.66 | 1,851 | BKLXFX5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,625.27 | 559 | BS2F741 |
| 0.02% | ARVN | ARVINAS INC | -- | $17,518.28 | 2,284 | BDZ30Q0 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,366.64 | 2,152 | BSMLR16 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $16,547.29 | 1,853 | B91XRN2 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $16,392.48 | 5,772 | BK5MWR1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $16,243.10 | 3,914 | BKX9NQ0 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,454.53 | 2,331 | BDRJH21 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,447.60 | 11,034 | B4N8MH9 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,055.60 | 532 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $14,927.02 | 2,042 | B2Q9833 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $14,614.77 | 5,433 | BZ8FPH3 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $14,468.88 | 2,166 | BP2NYN2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $14,274.00 | 1,830 | BZ0G875 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,826.52 | 1,158 | BPRBTY7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $13,705.40 | 2,780 | BQ6C357 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,623.12 | 1,802 | B7F2TY6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,387.92 | 3,678 | BMXNGZ6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $13,027.14 | 1,029 | B9L5200 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,951.10 | 3,866 | BDFKQ07 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,351.88 | 2,833 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,348.20 | 2,129 | B12W3P6 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,037.50 | 1,926 | BRCFFK6 |
| 0.02% | OABI | OMNIAB INC | -- | $12,008.88 | 5,132 | BN13S71 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,524.59 | 1,663 | BL5B6Z1 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $10,968.48 | 2,539 | 2107437 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,722.51 | 7,101 | BFMLGR4 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $10,523.24 | 826 | BTNMG41 |
| 0.01% | IVVD | INVIVYD INC | -- | $10,115.09 | 10,429 | BM8NHS1 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,098.90 | 2,290 | BMVBZF5 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,945.52 | 1,898 | BP7L561 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,904.09 | 6,559 | BN4JN37 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,741.66 | 1,374 | BP81RK8 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,957.13 | 3,281 | BYTYP72 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,728.30 | 2,359 | BJDX8Z9 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,647.20 | 3,603 | BZC0D70 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,627.85 | 2,079 | BMF7DT9 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,458.80 | 2,120 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,285.68 | 3,224 | B5LL2C2 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,082.28 | 5,461 | BRK0149 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,957.08 | 2,139 | BY7RB53 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,575.18 | 1,006 | BKC9SX3 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $7,465.65 | 701 | BM7V485 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,357.12 | 1,328 | 2517058 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,265.78 | 7,860 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,996.00 | 7,003 | BNR5QT9 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $6,826.50 | 1,110 | BQV0J03 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $6,604.00 | 1,651 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $5,961.00 | 3,974 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $5,758.04 | 3,511 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,612.47 | 7,682 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,553.29 | 2,243 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,383.71 | 2,449 | BMTX3D7 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $4,197.96 | 2,691 | BPTK6Z2 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,368.14 | 2,029 | BKTV702 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,113.17 | 3,979 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,033.96 | 772 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,395.74 | 8,308 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 36.26% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 26,809,197 | -- | 4,453 | -- |
| 28.69% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,216,172 | -- | 3,524 | -- |
| 24.98% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 18,470,833 | -- | 3,068 | -- |
| 21.49% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,888,047 | -- | 2,639 | -- |
| 20.46% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 15,129,466 | -- | 2,513 | -- |
| 5.15% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,810,964 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $22,327,360.33 | 22,327,360 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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