BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 12/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/26/2026- NAV $86.37
- NAV Change $+0.68
- Market Price $86.37
- Market Price Change $+0.64
- Trading Volume (M) 8,645
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/26/2026- NAV $86.37
- NAV Change $+0.68
- Market Price $86.37
- Market Price Change $+0.64
- Trading Volume (M) 8,645
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 1/26/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.08% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,509,886.20 | 11,555 | 2931034 |
| 6.05% | GILD | GILEAD SCIENCES INC | -- | $5,485,572.92 | 39,814 | 2369174 |
| 5.59% | AMGN | AMGEN INC | -- | $5,071,554.07 | 14,503 | 2023607 |
| 4.00% | REGN | REGENERON PHARMACEUTICALS | -- | $3,628,688.70 | 4,758 | 2730190 |
| 2.43% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,201,344.20 | 6,092 | B00FWN1 |
| 1.73% | INSM | INSMED INC | -- | $1,569,408.72 | 9,826 | 2614487 |
| 1.29% | BIIB | BIOGEN INC | -- | $1,170,118.08 | 6,759 | 2455965 |
| 1.23% | ARGX | ARGENX SE - ADR | -- | $1,117,267.56 | 1,341 | BDVLM39 |
| 1.19% | ILMN | ILLUMINA INC | -- | $1,077,120.00 | 7,040 | 2613990 |
| 1.04% | UTHR | UNITED THERAPEUTICS CORP | -- | $939,146.24 | 1,984 | 2430412 |
| 1.02% | INCY | INCYTE CORP | -- | $927,836.10 | 9,045 | 2471950 |
| 0.96% | RVMD | REVOLUTION MEDICINES INC | -- | $870,926.46 | 8,907 | BL71K91 |
| 0.95% | MRNA | MODERNA INC | -- | $863,772.01 | 17,999 | BGSXTS3 |
| 0.88% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $796,490.07 | 19,681 | BMVP7Y0 |
| 0.86% | MEDP | MEDPACE HOLDINGS INC | -- | $782,075.94 | 1,299 | BDCBC61 |
| 0.80% | ROIV | ROIVANT SCIENCES LTD | -- | $728,496.50 | 32,050 | BMW4NZ9 |
| 0.77% | VTRS | VIATRIS INC | -- | $698,852.88 | 53,064 | BMWS3X9 |
| 0.76% | BBIO | BRIDGEBIO PHARMA INC | -- | $690,797.18 | 8,878 | BK1KWG8 |
| 0.75% | GH | GUARDANT HEALTH INC | -- | $683,965.14 | 5,961 | BFXC911 |
| 0.73% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $660,995.85 | 2,829 | BV9G6B8 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $617,938.94 | 4,594 | 2623911 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $604,422.00 | 7,462 | BDJ0LS6 |
| 0.64% | SNY | SANOFI-ADR | -- | $577,047.36 | 12,192 | 2964557 |
| 0.63% | SMMT | SUMMIT THERAPEUTICS INC | -- | $567,974.88 | 34,298 | BMTVQS7 |
| 0.61% | BNTX | BIONTECH SE-ADR | -- | $549,644.00 | 4,658 | BK6H543 |
| 0.59% | EXEL | EXELIXIS INC | -- | $538,801.55 | 12,355 | 2576941 |
| 0.59% | TEM | TEMPUS AI INC | -- | $538,672.95 | 7,965 | BSLSJJ0 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $523,130.16 | 1,048 | BD59BS7 |
| 0.56% | RNA | AVIDITY BIOSCIENCES INC | -- | $504,197.46 | 6,942 | BMWHPY1 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $502,616.56 | 8,852 | 2437071 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $489,795.50 | 1,450 | BYYWPW6 |
| 0.51% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $465,780.00 | 2,800 | B4Q5ZN4 |
| 0.47% | AXSM | AXSOME THERAPEUTICS INC | -- | $428,455.44 | 2,322 | BYZR4X4 |
| 0.46% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $417,691.82 | 6,251 | BYQBFJ8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $378,555.66 | 5,418 | 2975098 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $372,410.00 | 1,336 | BD6JX35 |
| 0.39% | CYTK | CYTOKINETICS INC | -- | $355,949.27 | 5,633 | BBBSBJ5 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $352,907.29 | 3,329 | BMVBZD3 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $338,734.08 | 1,152 | BQ721R4 |
| 0.37% | CAI | CARIS LIFE SCIENCES INC | -- | $335,244.21 | 12,999 | BT18HP9 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $328,672.72 | 2,719 | BLC89B2 |
| 0.36% | PCVX | VAXCYTE INC | -- | $322,055.40 | 6,031 | BKPVGH6 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $317,820.86 | 3,074 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $281,974.77 | 3,699 | B17VCN9 |
| 0.31% | IBRX | IMMUNITYBIO INC | -- | $281,809.80 | 45,380 | BNSP0B8 |
| 0.30% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $275,696.46 | 3,078 | BQS9486 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $267,859.50 | 7,075 | BLR6XK8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $251,900.88 | 7,608 | B3P6D26 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $240,186.75 | 4,395 | BDHF4K6 |
| 0.26% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $237,024.00 | 2,880 | BDCBCD8 |
| 0.26% | KYMR | KYMERA THERAPEUTICS INC | -- | $235,563.90 | 3,315 | BMPRZV5 |
| 0.25% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $229,722.48 | 4,374 | BDD19F8 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $229,506.56 | 2,368 | BJDX8Y8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $214,874.80 | 8,078 | BJRFSB7 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $211,072.78 | 4,702 | BFZQ0L8 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $209,373.70 | 7,795 | 2713317 |
| 0.22% | FOLD | AMICUS THERAPEUTICS INC | -- | $203,132.35 | 14,215 | B19FQ48 |
| 0.22% | CGON | CG ONCOLOGY INC | -- | $198,062.80 | 3,716 | BRBCSP4 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $196,534.31 | 14,483 | BFNF1D6 |
| 0.21% | -- | INDIVIOR PHARMACEUTICALS INC COMMON STOCK USD 0.001 | -- | $193,219.32 | 5,754 | -- |
| 0.21% | GRAL | GRAIL INC | -- | $190,932.76 | 1,796 | BSLSSX7 |
| 0.21% | ADMA | ADMA BIOLOGICS INC | -- | $185,966.40 | 10,965 | B9NSBM2 |
| 0.20% | ACLX | ARCELLX INC | -- | $182,617.20 | 2,664 | BPCJ1Q2 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $179,785.54 | 907 | 2501578 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $176,940.54 | 2,527 | BM9HHL5 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $169,100.88 | 5,224 | BP8JSP4 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $150,316.40 | 3,562 | BRJ3GY4 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $148,523.76 | 5,643 | BKX9VD3 |
| 0.16% | VCYT | VERACYTE INC | -- | $147,755.94 | 3,642 | BFTWZY0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $144,691.25 | 4,675 | BK6L288 |
| 0.16% | TERN | TERNS PHARMACEUTICALS INC | -- | $143,001.95 | 4,151 | BMDJ0C9 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $139,261.77 | 6,757 | BD2B4V0 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $139,224.33 | 4,039 | BK0VHF6 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $139,062.90 | 2,945 | BL55460 |
| 0.15% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $136,681.56 | 4,878 | BKY5JZ8 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $134,919.60 | 1,740 | BMGJZJ8 |
| 0.15% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $134,394.48 | 7,029 | BJ5FZ74 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $132,822.70 | 1,955 | BMH5RL1 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $129,880.72 | 2,642 | B72ZBG4 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $128,201.70 | 5,830 | BYTQ6X1 |
| 0.14% | ERAS | ERASCA INC | -- | $125,612.31 | 13,071 | BNLYBF3 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $123,412.68 | 4,122 | BLFGJD5 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $120,802.50 | 5,369 | BKS3RS7 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $120,463.84 | 3,646 | BP9N0G0 |
| 0.13% | TWST | TWIST BIOSCIENCE CORP | -- | $119,652.28 | 2,818 | BGKG6G7 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $118,440.00 | 6,580 | BN15WD1 |
| 0.13% | ALMS | ALUMIS INC | -- | $117,842.49 | 4,479 | BPLQG36 |
| 0.13% | SYRE | SPYRE THERAPEUTICS INC | -- | $115,404.46 | 3,574 | BQBBDY8 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $114,369.85 | 4,445 | BLB0YQ9 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $110,055.60 | 4,827 | B8DPDT7 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $108,737.10 | 23,690 | BM9FJ13 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $108,057.95 | 4,445 | BJ62Z18 |
| 0.12% | OCUL | OCULAR THERAPEUTIX INC | -- | $106,939.80 | 9,820 | BNZB1X8 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $102,051.50 | 7,702 | BYZG9R0 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $99,153.44 | 2,654 | BKSGZN7 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $98,833.86 | 2,217 | BSRK699 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $90,875.98 | 3,622 | BMZ4LN0 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $90,134.71 | 2,693 | BBC9WC7 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $89,899.20 | 2,081 | BRXB0C0 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,525.06 | 6,086 | BFWLC09 |
| 0.10% | VCEL | VERICEL CORP | -- | $87,841.00 | 2,330 | BSBMN89 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $87,585.60 | 2,056 | BQKXDX4 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $87,562.50 | 4,670 | BMVLGP2 |
| 0.10% | ARDX | ARDELYX INC | -- | $87,321.00 | 11,195 | BN89V40 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $85,707.00 | 4,005 | BN7Q7R7 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $84,176.55 | 1,035 | BCDWBX6 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $83,963.20 | 5,410 | BRJZSK0 |
| 0.09% | PHVS | PHARVARIS NV | -- | $81,418.09 | 2,951 | BMZ2X38 |
| 0.09% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $79,177.41 | 3,441 | BYP80F1 |
| 0.09% | MNKD | MANNKIND CORP | -- | $79,023.96 | 14,162 | BF081J4 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $78,993.68 | 3,448 | BPCQZY9 |
| 0.09% | PGEN | PRECIGEN INC | -- | $77,610.25 | 16,339 | BKM5C84 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $77,437.38 | 2,686 | BCBVTX1 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $76,956.75 | 2,631 | BJQ05Z6 |
| 0.08% | ALVO | ALVOTECH SA | -- | $76,869.26 | 14,422 | BPNTJ34 |
| 0.08% | ORKA | ORUKA THERAPEUTICS INC | -- | $76,121.72 | 2,231 | BKVF0J2 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $75,935.59 | 5,059 | BPCK358 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $75,725.40 | 2,069 | BQXJKH2 |
| 0.08% | UPB | UPSTREAM BIO INC | -- | $75,098.40 | 2,490 | BRCFFK6 |
| 0.08% | -- | DEFINIUM THERAPEUTICS INC COMMON STOCK USD 0 | -- | $74,922.38 | 4,538 | -- |
| 0.08% | HROW | HARROW INC | -- | $74,817.81 | 1,707 | BHNDW86 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $74,493.00 | 5,340 | BYZM6C2 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $74,188.03 | 2,459 | BMVNDH9 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $73,580.74 | 1,277 | BTJZB49 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $73,545.84 | 3,879 | BMX9K07 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $72,624.42 | 4,257 | BRXYZ57 |
| 0.08% | QURE | UNIQURE NV | -- | $72,524.90 | 2,870 | BJFSR88 |
| 0.08% | TNGX | TANGO THERAPEUTICS INC | -- | $72,474.40 | 6,205 | BP2P6L0 |
| 0.08% | NVAX | NOVAVAX INC | -- | $72,099.81 | 7,487 | BJDQXG4 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $70,728.58 | 2,734 | BMFD115 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $70,470.60 | 2,010 | BLCD809 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $68,408.34 | 5,159 | BYSS4X4 |
| 0.07% | INVA | INNOVIVA INC | -- | $67,246.40 | 3,445 | BDDXF67 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $67,170.00 | 3,000 | BP7KZP7 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,713.92 | 1,456 | BX7RSN3 |
| 0.07% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $66,542.00 | 9,700 | 2100362 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $65,258.70 | 16,733 | BWJDYK1 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $62,713.04 | 2,444 | BFXC933 |
| 0.07% | RLAY | RELAY THERAPEUTICS INC | -- | $60,644.10 | 7,990 | BN2R582 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $60,125.12 | 1,276 | BDRW1L7 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $59,966.20 | 5,908 | BJH9ZN0 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $59,566.40 | 12,620 | BNC1BX1 |
| 0.07% | EYPT | EYEPOINT INC | -- | $59,003.55 | 3,819 | BMGS7L1 |
| 0.06% | SANA | SANA BIOTECHNOLOGY INC | -- | $58,537.44 | 12,272 | BMFJJ97 |
| 0.06% | RAPP | RAPPORT THERAPEUTICS INC | -- | $58,004.85 | 2,193 | BR3T9B6 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $57,888.80 | 1,345 | BKLCWZ3 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $57,177.12 | 7,644 | BLR7H87 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $57,094.74 | 13,791 | BL53SR3 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $56,913.93 | 4,731 | BLB0YH0 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $56,312.20 | 2,117 | BNFWZS4 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $54,965.75 | 4,487 | BKVDFF7 |
| 0.06% | SVRA | SAVARA INC | -- | $54,181.72 | 9,374 | BYXGN81 |
| 0.06% | SEPN | SEPTERNA INC | -- | $53,576.11 | 2,063 | BQNKXX2 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $53,086.41 | 18,369 | BF0DMK7 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $51,713.20 | 5,621 | B8K7T65 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $48,240.00 | 670 | BNSP8K3 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $47,894.28 | 2,479 | BQB42H3 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $47,754.50 | 6,410 | BK4PZ38 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $47,725.92 | 4,554 | BMCR7V2 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $47,442.80 | 2,858 | BP6C0S2 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $46,205.88 | 3,284 | BJLKVS6 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $46,096.50 | 2,334 | BMNDK09 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $45,919.39 | 3,287 | BMG99Y1 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $45,469.56 | 2,157 | BZ7PJQ1 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,887.20 | 1,902 | BMGTLY5 |
| 0.05% | ANNX | ANNEXON INC | -- | $44,515.44 | 6,684 | BMVV9R5 |
| 0.05% | XNCR | XENCOR INC | -- | $42,835.80 | 3,290 | BGCYWN8 |
| 0.05% | PSNL | PERSONALIS INC | -- | $42,382.76 | 4,091 | BJQ0608 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $42,198.12 | 2,259 | BQS7491 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $41,764.14 | 7,821 | BYWVTY5 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $41,476.92 | 2,526 | BQB42F1 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,631.00 | 1,982 | B3X26D8 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $40,567.44 | 2,771 | BMFX8Y7 |
| 0.04% | GERN | GERON CORP | -- | $40,291.70 | 29,410 | 2370381 |
| 0.04% | ARVN | ARVINAS INC | -- | $39,325.11 | 2,959 | BDZ30Q0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $38,736.04 | 7,478 | B3MZ6K5 |
| 0.04% | OMER | OMEROS CORP | -- | $37,668.51 | 3,267 | B4NB858 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $37,190.16 | 942 | BL95N25 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $36,786.76 | 11,014 | BBNBTD2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,238.56 | 8,882 | BZ0QMB7 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $35,053.20 | 13,910 | B4N8MH9 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $34,806.86 | 8,327 | BPBJFM7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $34,740.30 | 2,330 | BD06CS0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,357.13 | 4,009 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $32,582.34 | 2,722 | BM90J52 |
| 0.04% | RGNX | REGENXBIO INC | -- | $32,309.86 | 2,332 | BZ0G875 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,804.92 | 1,803 | BD9GVY0 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $30,969.00 | 837 | BQD3J33 |
| 0.03% | BIOA | BIOAGE LABS INC | -- | $30,182.04 | 1,652 | BT9K6D8 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $29,952.90 | 4,341 | BMC3HS7 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,672.00 | 3,709 | BFYQFJ2 |
| 0.03% | LENZ | LENZ THERAPEUTICS INC | -- | $29,079.38 | 1,441 | BQV0J03 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $28,422.10 | 10,685 | BJ0CK86 |
| 0.03% | CRMD | CORMEDIX INC | -- | $28,168.80 | 3,630 | BJ0LT31 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,447.04 | 2,624 | BMFK3H6 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $27,321.84 | 3,614 | BDDVW37 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $27,213.28 | 4,808 | BFY7DC4 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $27,198.63 | 2,493 | BJDX8Z9 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $26,353.08 | 1,404 | BM7V485 |
| 0.03% | IVVD | INVIVYD INC | -- | $26,172.35 | 12,767 | BM8NHS1 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $25,248.62 | 3,362 | BQ6C357 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,719.70 | 6,681 | BMCWKZ2 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,651.20 | 2,480 | B91XRN2 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $24,352.20 | 978 | BTNMG41 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,397.88 | 2,594 | BLFBZ32 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,149.05 | 3,589 | BQHN6C7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $23,003.64 | 666 | B292NQ7 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,752.48 | 2,658 | B2Q9833 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,400.21 | 3,299 | 2107437 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $21,184.94 | 2,723 | B12W3P6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,977.04 | 2,632 | BKLXFX5 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $20,687.42 | 4,121 | BYTYP72 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,021.92 | 6,928 | BN94K69 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,547.10 | 1,761 | BP81RK8 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,069.44 | 4,992 | BYV2W40 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $19,016.30 | 4,790 | BKRRKY7 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $18,660.85 | 1,235 | BGL0JK3 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,212.04 | 5,621 | BYVQJ96 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,099.18 | 4,986 | BDFKQ07 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,919.84 | 2,018 | BSMLR16 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,183.60 | 1,330 | B9L5200 |
| 0.02% | PEPG | PEPGEN INC | -- | $16,816.77 | 3,167 | BMTX3D7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,619.36 | 862 | BPBPCG8 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,356.34 | 2,926 | BP81R42 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $16,098.48 | 4,626 | BZC0D70 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,703.92 | 7,698 | BN4JN37 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,634.54 | 10,354 | BFZNYB7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,550.38 | 2,979 | BMVBZF5 |
| 0.02% | LFCR | LIFECORE BIOMEDICAL INC | -- | $15,232.14 | 1,727 | 2517058 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,205.30 | 2,530 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,140.86 | 2,606 | BMF7DT9 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,924.03 | 2,321 | B7F2TY6 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $14,924.00 | 2,132 | BKDQKM6 |
| 0.02% | AARD | AARDVARK THERAPEUTICS INC | -- | $14,804.28 | 1,003 | BTXQTX3 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,396.00 | 3,599 | BLN9Z50 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,392.52 | 2,986 | BDRJH21 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,194.80 | 3,943 | BMXNGZ6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,781.10 | 1,065 | BPRBTY7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,632.56 | 713 | BS2F741 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $13,083.25 | 4,435 | BK5MWR1 |
| 0.01% | OABI | OMNIAB INC | -- | $12,934.35 | 6,633 | BN13S71 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,846.38 | 9,242 | BFMLGR4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $12,697.32 | 5,569 | BRK0149 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,750.52 | 2,164 | BL5B6Z1 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $11,694.32 | 776 | BRJJYT3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,900.89 | 9,009 | BNR5QT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,876.00 | 2,719 | BY7RB53 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $10,470.98 | 3,502 | BPTK6Z2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,277.90 | 2,602 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,634.24 | 1,309 | BKC9SX3 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,265.88 | 4,498 | BZ8FPH3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,242.55 | 4,465 | BKX9NQ0 |
| 0.01% | HUMA | HUMACYTE INC | -- | $8,800.56 | 8,628 | BMYTJP4 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,628.93 | 1,431 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,841.88 | 2,466 | BP7L561 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,720.00 | 2,625 | BKTV702 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,588.18 | 4,306 | BNYJR68 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,449.55 | 4,161 | B5LL2C2 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,201.72 | 4,494 | BNNXX18 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,416.43 | 7,672 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,619.09 | 2,869 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $15.64 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 41.35% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,505,417 | -- | 6,292 | -- |
| 29.11% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,400,427 | -- | 4,429 | -- |
| 23.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,321,817 | -- | 3,577 | -- |
| 17.35% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,730,578 | -- | 2,639 | -- |
| 16.33% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,806,652 | -- | 2,484 | -- |
| 4.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,773,193 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $29,184,208.07 | 29,184,208 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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