BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,825,504
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/05/2026- NAV
- NAV Change
- Market Price $80.27
- Market Price Change $-2.81
- Trading Volume (M) 3,111
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $69,825,504
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/05/2026- NAV
- NAV Change
- Market Price $80.27
- Market Price Change $-2.81
- Trading Volume (M) 3,111
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/05/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.91% | AMGN | AMGEN INC | -- | $3,426,932.74 | 9,803 | 2023607 |
| 4.90% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,421,377.31 | 7,657 | 2931034 |
| 4.72% | GILD | GILEAD SCIENCES INC | -- | $3,299,004.72 | 25,542 | 2369174 |
| 3.49% | REGN | REGENERON PHARMACEUTICALS | -- | $2,440,128.00 | 3,840 | 2730190 |
| 2.13% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,486,157.20 | 4,904 | B00FWN1 |
| 1.57% | RVMD | REVOLUTION MEDICINES INC | -- | $1,093,258.98 | 7,326 | BL71K91 |
| 1.52% | BIIB | BIOGEN INC | -- | $1,059,719.50 | 5,425 | 2455965 |
| 1.34% | ARGX | ARGENX SE - ADR | -- | $935,886.00 | 1,050 | BDVLM39 |
| 1.31% | ILMN | ILLUMINA INC | -- | $917,594.96 | 5,653 | 2613990 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $890,789.40 | 1,620 | 2430412 |
| 1.27% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $884,813.19 | 15,837 | BMVP7Y0 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $756,226.80 | 26,460 | BMW4NZ9 |
| 1.08% | INCY | INCYTE CORP | -- | $753,414.42 | 7,359 | 2471950 |
| 1.08% | INSM | INSMED INC | -- | $750,744.96 | 7,968 | 2614487 |
| 0.99% | MRNA | MODERNA INC | -- | $692,624.00 | 14,600 | BGSXTS3 |
| 0.97% | VTRS | VIATRIS INC | -- | $675,932.20 | 42,565 | BMWS3X9 |
| 0.87% | GH | GUARDANT HEALTH INC | -- | $609,208.50 | 4,850 | BFXC911 |
| 0.87% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $608,322.56 | 3,712 | 2623911 |
| 0.78% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $542,746.75 | 2,275 | B4Q5ZN4 |
| 0.72% | EXEL | EXELIXIS INC | -- | $505,920.00 | 9,600 | 2576941 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $484,560.87 | 7,167 | BK1KWG8 |
| 0.69% | ASND | ASCENDIS PHARMA A/S | -- | $478,984.20 | 2,276 | BWXJHM8 |
| 0.68% | MEDP | MEDPACE HOLDINGS INC | -- | $477,416.75 | 1,051 | BDCBC61 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $454,998.32 | 6,109 | BDJ0LS6 |
| 0.63% | AXSM | AXSOME THERAPEUTICS INC | -- | $439,084.80 | 1,890 | BYZR4X4 |
| 0.61% | SMMT | SUMMIT THERAPEUTICS INC | -- | $423,367.28 | 28,664 | BMTVQS7 |
| 0.59% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $412,472.06 | 847 | BD59BS7 |
| 0.58% | SNY | SANOFI-ADR | -- | $407,295.94 | 9,047 | 2964557 |
| 0.58% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $403,634.70 | 7,110 | 2437071 |
| 0.54% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $378,460.02 | 5,178 | BYQBFJ8 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $371,081.04 | 4,213 | BK6H543 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $325,448.44 | 4,553 | BBBSBJ5 |
| 0.47% | KRYS | KRYSTAL BIOTECH INC | -- | $325,080.00 | 1,080 | BD6JX35 |
| 0.46% | ONC | BEONE MEDICINES LTD-ADR | -- | $318,988.10 | 1,181 | BYYWPW6 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $312,156.92 | 4,364 | 2975098 |
| 0.43% | TEM | TEMPUS AI INC-CL A | -- | $298,266.32 | 6,424 | BSLSJJ0 |
| 0.38% | ALKS | ALKERMES PLC | -- | $263,776.40 | 6,163 | B3P6D26 |
| 0.38% | IBRX | IMMUNITYBIO INC | -- | $263,015.36 | 38,008 | BNSP0B8 |
| 0.37% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $261,366.00 | 1,029 | BQ721R4 |
| 0.36% | PCVX | VAXCYTE INC | -- | $252,002.56 | 5,321 | BKPVGH6 |
| 0.35% | NUVL | NUVALENT INC-A | -- | $246,019.75 | 2,705 | BMVBZD3 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $234,040.53 | 7,523 | BJRFSB7 |
| 0.33% | ABVX | ABIVAX SA-ADR | -- | $230,574.63 | 2,271 | BLC89B2 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $229,914.18 | 2,361 | BDCBCD8 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $223,650.21 | 3,017 | BMPRZV5 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $218,246.40 | 2,526 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $217,310.14 | 3,062 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $213,953.25 | 2,905 | BQBBDY8 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $208,553.88 | 2,231 | BJDX8Y8 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $186,182.04 | 6,002 | BLR6XK8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,032.00 | 3,550 | BDHF4K6 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $176,273.76 | 2,028 | BM9HHL5 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,239.26 | 4,423 | BLB0YQ9 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $174,432.00 | 736 | 2501578 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,931.76 | 4,624 | BTZRLN8 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $172,007.19 | 10,431 | BT18HP9 |
| 0.24% | CGON | CG ONCOLOGY INC | -- | $167,767.56 | 3,123 | BRBCSP4 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $167,143.90 | 3,773 | BFZQ0L8 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $159,940.00 | 11,632 | BFNF1D6 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $159,018.02 | 3,074 | BRJ3GY4 |
| 0.22% | TWST | TWIST BIOSCIENCE CORP | -- | $156,852.52 | 2,266 | BGKG6G7 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $156,166.29 | 3,409 | BLFGJD5 |
| 0.21% | VCYT | VERACYTE INC | -- | $143,168.74 | 2,938 | BFTWZY0 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $141,149.94 | 3,966 | BKY5JZ8 |
| 0.20% | ERAS | ERASCA INC | -- | $136,984.68 | 11,444 | BNLYBF3 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $135,892.68 | 6,303 | 2713317 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $135,055.04 | 4,351 | BKS3RS7 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $134,023.04 | 4,252 | BP8JSP4 |
| 0.18% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $127,466.24 | 3,872 | BDD19F8 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $114,445.76 | 5,863 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $110,749.80 | 3,767 | BK6L288 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $108,230.40 | 2,880 | BQS9486 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $107,590.46 | 1,789 | BKVF0J2 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $103,722.48 | 6,087 | BN15WD1 |
| 0.15% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $101,839.64 | 3,122 | BMX9K07 |
| 0.14% | TNGX | TANGO THERAPEUTICS INC | -- | $100,655.16 | 4,978 | BP2P6L0 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $97,382.01 | 4,587 | BKX9VD3 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $96,194.80 | 5,692 | BJ5FZ74 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $94,870.00 | 2,120 | B72ZBG4 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $94,537.00 | 1,411 | BMGJZJ8 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $93,247.44 | 1,573 | BMH5RL1 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $91,829.34 | 3,246 | BK0VHF6 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $89,313.12 | 6,606 | BN2R582 |
| 0.13% | ALMS | ALUMIS INC | -- | $89,086.44 | 4,674 | BPLQG36 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $86,781.75 | 3,685 | BV2DHY6 |
| 0.12% | GRAL | GRAIL INC | -- | $86,311.22 | 1,439 | BSLSSX7 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $85,116.44 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $82,217.16 | 1,698 | BRXB0C0 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $78,240.61 | 3,571 | BJ62Z18 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $77,969.11 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $77,837.76 | 4,914 | BFWLC09 |
| 0.11% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $76,223.16 | 2,196 | BMFD115 |
| 0.11% | PHVS | PHARVARIS NV | -- | $73,590.03 | 2,367 | BMZ2X38 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $72,226.44 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $70,175.85 | 8,805 | B9NSBM2 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $70,017.75 | 2,255 | BFXC933 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $69,293.25 | 2,925 | BP9N0G0 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $68,908.00 | 2,140 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $68,062.50 | 1,875 | BSBMN89 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $67,321.30 | 830 | BCDWBX6 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $66,494.64 | 2,766 | BPCQZY9 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $66,404.25 | 8,049 | BNZB1X8 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $64,431.36 | 15,232 | BF0DMK7 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $63,969.56 | 19,297 | BM9FJ13 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $63,680.40 | 1,764 | BR3T9B6 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $63,351.11 | 2,111 | BJQ05Z6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $63,210.86 | 4,742 | BJH9ZN0 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $62,994.58 | 11,209 | BL53SR3 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,704.80 | 2,740 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $61,276.14 | 2,166 | BCBVTX1 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $61,031.25 | 3,875 | B8DPDT7 |
| 0.09% | QURE | UNIQURE NV | -- | $60,967.25 | 2,305 | BJFSR88 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $59,831.85 | 2,379 | BBC9WC7 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $59,156.26 | 4,369 | BYZM6C2 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $58,395.87 | 1,651 | BQKXDX4 |
| 0.08% | NVAX | NOVAVAX INC | -- | $57,158.27 | 6,023 | BJDQXG4 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $56,545.74 | 3,261 | BN7Q7R7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,704.00 | 10,128 | BNC1BX1 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $55,661.28 | 3,802 | BMVLGP2 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $55,556.40 | 3,455 | BRXYZ57 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $54,065.88 | 4,059 | BPCK358 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $53,044.55 | 13,429 | BWJDYK1 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $52,587.36 | 1,974 | BMVNDH9 |
| 0.07% | SEPN | SEPTERNA INC | -- | $51,615.55 | 1,657 | BQNKXX2 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $51,528.51 | 1,023 | BDRW1L7 |
| 0.07% | ARDX | ARDELYX INC | -- | $50,406.96 | 9,066 | BN89V40 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,396.50 | 1,870 | BD06CS0 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,256.50 | 5,810 | BK4PZ38 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $50,204.24 | 1,658 | BQXJKH2 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $49,160.42 | 2,294 | BP6C0S2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $46,860.00 | 2,343 | BQB42F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $46,826.40 | 13,080 | BKM5C84 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $46,724.37 | 537 | BNSP8K3 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $46,450.50 | 1,730 | BZ7PJQ1 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,344.45 | 1,527 | BMGTLY5 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $46,130.66 | 2,818 | BP7KZP7 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,858.09 | 1,621 | BLCD809 |
| 0.07% | HROW | HARROW INC | -- | $45,470.30 | 1,370 | BHNDW86 |
| 0.06% | ALVO | ALVOTECH SA | -- | $43,223.40 | 12,210 | BPNTJ34 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $43,152.06 | 1,778 | BSRK699 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $42,227.57 | 3,487 | BMC3HS7 |
| 0.06% | PSNL | PERSONALIS INC | -- | $41,591.75 | 3,869 | BJQ0608 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $39,880.80 | 6,960 | BYZG9R0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,121.36 | 1,172 | BX7RSN3 |
| 0.06% | MNKD | MANNKIND CORP | -- | $38,722.60 | 11,389 | BF081J4 |
| 0.05% | SVRA | SAVARA INC | -- | $38,297.16 | 7,524 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $37,908.12 | 6,134 | BLR7H87 |
| 0.05% | EYPT | EYEPOINT INC | -- | $36,070.36 | 3,062 | BMGS7L1 |
| 0.05% | ABSI | ABSCI CORP | -- | $35,590.40 | 5,561 | BN94K69 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $34,643.01 | 1,983 | BQB42H3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,456.40 | 4,510 | B8K7T65 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,011.25 | 1,495 | B3X26D8 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $33,960.48 | 3,054 | BYP80F1 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $33,103.98 | 1,677 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $31,908.47 | 2,711 | BGCYWN8 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,295.36 | 3,656 | BMCR7V2 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,543.75 | 1,875 | BMNDK09 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $30,538.22 | 2,962 | BMZ4LN0 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,217.50 | 7,110 | BZ0QMB7 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,073.36 | 2,251 | BMFX8Y7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,519.35 | 2,185 | BM90J52 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,498.56 | 2,912 | BJLKVS6 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $28,911.91 | 3,053 | BDDVW37 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $28,896.96 | 992 | BGL0JK3 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,296.21 | 5,349 | BMVV9R5 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,125.32 | 3,218 | BYZD465 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $27,832.50 | 3,711 | BKVDFF7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | GERN | GERON CORP | -- | $27,614.34 | 23,602 | 2370381 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,158.20 | 5,410 | BMCWKZ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,979.30 | 1,934 | BQS7491 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $26,775.00 | 2,975 | BFYQFJ2 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $26,395.32 | 9,849 | BMFJJ97 |
| 0.04% | OMER | OMEROS CORP | -- | $25,669.38 | 2,622 | B4NB858 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $25,182.80 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,744.09 | 763 | BL95N25 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,335.96 | 2,911 | BJ0LT31 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $23,111.00 | 1,100 | BKLCWZ3 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,036.57 | 2,707 | BP0TQC5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,418.25 | 2,105 | BMFK3H6 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,100.63 | 2,083 | BLFBZ32 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,090.78 | 1,269 | BD9GVY0 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $20,419.38 | 6,673 | BPBJFM7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $20,213.76 | 1,536 | BRJJYT3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,112.96 | 672 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,097.00 | 693 | BPBPCG8 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $19,952.68 | 6,028 | B3MZ6K5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,441.24 | 4,459 | BYV2W40 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $19,296.00 | 2,880 | BQHN6C7 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,795.00 | 6,265 | BYWVTY5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,728.23 | 4,511 | BYVQJ96 |
| 0.03% | ARVN | ARVINAS INC | -- | $17,533.46 | 2,363 | BDZ30Q0 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $17,483.31 | 1,989 | B91XRN2 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,981.80 | 1,023 | BS2CR64 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,286.40 | 1,885 | BKLXFX5 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $16,186.35 | 11,163 | B4N8MH9 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,987.99 | 2,397 | BDRJH21 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $15,776.64 | 2,112 | BSMLR16 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,619.04 | 8,308 | BFZNYB7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $15,573.87 | 2,349 | BP81R42 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,354.96 | 548 | B292NQ7 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,300.78 | 2,134 | B2Q9833 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,125.79 | 571 | BS2F741 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $14,078.85 | 1,997 | BRCFFK6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $13,894.65 | 3,609 | BKX9NQ0 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,209.37 | 1,879 | B7F2TY6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,198.56 | 5,322 | BN13S71 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,181.58 | 2,186 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,914.76 | 1,124 | BPRBTY7 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,724.38 | 4,014 | BMXNGZ6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,550.01 | 4,631 | BFY7DC4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,278.25 | 2,889 | BLN9Z50 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,092.16 | 1,072 | B9L5200 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,785.89 | 2,697 | BQ6C357 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,587.50 | 1,125 | BM7V485 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,560.25 | 3,557 | BK5MWR1 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,387.84 | 1,873 | BZ0G875 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,377.80 | 2,646 | 2107437 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,343.42 | 7,414 | BFMLGR4 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,035.75 | 4,013 | BDFKQ07 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,711.12 | 1,736 | BL5B6Z1 |
| 0.02% | IVVD | INVIVYD INC | -- | $10,551.32 | 10,244 | BM8NHS1 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,192.49 | 2,387 | BMVBZF5 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,066.88 | 6,176 | BN4JN37 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,785.81 | 3,611 | BZ8FPH3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,633.60 | 7,136 | BMYTJP4 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,420.39 | 787 | BTNMG41 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $9,092.16 | 2,464 | BJDX8Z9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,033.36 | 1,981 | BP7L561 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,019.92 | 1,416 | BP81RK8 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,804.82 | 3,426 | BYTYP72 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,552.96 | 3,341 | B5LL2C2 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,372.25 | 3,721 | BZC0D70 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,147.10 | 2,089 | BPRB2N7 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,117.58 | 1,158 | BQV0J03 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,075.45 | 2,165 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,011.25 | 5,525 | BRK0149 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,808.81 | 1,387 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,753.72 | 1,147 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,679.60 | 1,052 | BKC9SX3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,591.50 | 7,230 | BNR5QT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,256.07 | 2,179 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,186.20 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,828.40 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,631.68 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,833.54 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,540.86 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,146.85 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,099.34 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,582.81 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,992.84 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,958.72 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,497.13 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 29.49% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,587,278 | -- | 3,524 | -- |
| 29.34% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 20,487,964 | -- | 3,507 | -- |
| 28.23% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,710,975 | -- | 3,374 | -- |
| 22.08% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,417,091 | -- | 2,639 | -- |
| 21.03% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,680,996 | -- | 2,513 | -- |
| 5.30% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,697,999 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $19,531,295.41 | 19,531,295 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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