BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $80,355,244
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/06/2026- NAV
- NAV Change
- Market Price $86.37
- Market Price Change $+3.53
- Trading Volume (M) 7,053
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $80,355,244
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/06/2026- NAV
- NAV Change
- Market Price $86.37
- Market Price Change $+3.53
- Trading Volume (M) 7,053
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/06/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.77% | GILD | GILEAD SCIENCES INC | -- | $3,832,892.30 | 28,121 | 2369174 |
| 4.49% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,604,661.85 | 8,429 | 2931034 |
| 4.45% | AMGN | AMGEN INC | -- | $3,573,008.01 | 10,791 | 2023607 |
| 3.79% | REGN | REGENERON PHARMACEUTICALS | -- | $3,047,878.35 | 4,227 | 2730190 |
| 2.03% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,634,988.00 | 5,396 | B00FWN1 |
| 1.52% | RVMD | REVOLUTION MEDICINES INC | -- | $1,218,379.55 | 8,065 | BL71K91 |
| 1.50% | INSM | INSMED INC | -- | $1,202,690.57 | 8,773 | 2614487 |
| 1.42% | BIIB | BIOGEN INC | -- | $1,138,550.28 | 5,971 | 2455965 |
| 1.32% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,064,023.08 | 1,783 | 2430412 |
| 1.16% | ARGX | ARGENX SE - ADR | -- | $932,720.25 | 1,155 | BDVLM39 |
| 1.10% | ILMN | ILLUMINA INC | -- | $887,417.92 | 6,224 | 2613990 |
| 1.10% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $884,353.92 | 17,436 | BMVP7Y0 |
| 1.04% | ROIV | ROIVANT SCIENCES LTD | -- | $839,641.88 | 29,134 | BMW4NZ9 |
| 1.01% | INCY | INCYTE CORP | -- | $808,984.70 | 8,102 | 2471950 |
| 0.98% | MRNA | MODERNA INC | -- | $784,201.67 | 16,073 | BGSXTS3 |
| 0.93% | VTRS | VIATRIS INC | -- | $747,496.75 | 46,865 | BMWS3X9 |
| 0.75% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $600,723.72 | 4,086 | 2623911 |
| 0.74% | ASND | ASCENDIS PHARMA A/S | -- | $590,929.50 | 2,505 | BWXJHM8 |
| 0.71% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $572,567.85 | 2,505 | B4Q5ZN4 |
| 0.70% | SMMT | SUMMIT THERAPEUTICS INC | -- | $563,346.00 | 31,560 | BMTVQS7 |
| 0.67% | BBIO | BRIDGEBIO PHARMA INC | -- | $537,298.19 | 7,891 | BK1KWG8 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $516,816.25 | 6,725 | BDJ0LS6 |
| 0.64% | EXEL | EXELIXIS INC | -- | $514,807.70 | 10,571 | 2576941 |
| 0.63% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $504,107.82 | 934 | BD59BS7 |
| 0.61% | MEDP | MEDPACE HOLDINGS INC | -- | $492,942.45 | 1,155 | BDCBC61 |
| 0.61% | GH | GUARDANT HEALTH INC | -- | $492,338.25 | 5,337 | BFXC911 |
| 0.58% | AXSM | AXSOME THERAPEUTICS INC | -- | $463,515.66 | 2,082 | BYZR4X4 |
| 0.56% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $451,256.28 | 5,702 | BYQBFJ8 |
| 0.55% | BNTX | BIONTECH SE-ADR | -- | $441,720.62 | 4,637 | BK6H543 |
| 0.54% | SNY | SANOFI-ADR | -- | $435,949.20 | 9,960 | 2964557 |
| 0.53% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $427,408.80 | 7,828 | 2437071 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $407,629.32 | 1,301 | BYYWPW6 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $383,371.38 | 1,134 | BQ721R4 |
| 0.47% | TEM | TEMPUS AI INC-CL A | -- | $378,245.00 | 7,070 | BSLSJJ0 |
| 0.47% | CYTK | CYTOKINETICS INC | -- | $375,247.76 | 5,014 | BBBSBJ5 |
| 0.44% | IBRX | IMMUNITYBIO INC | -- | $350,694.62 | 41,849 | BNSP0B8 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $344,476.08 | 1,192 | BD6JX35 |
| 0.42% | PCVX | VAXCYTE INC | -- | $334,434.70 | 5,857 | BKPVGH6 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $318,745.40 | 4,804 | 2975098 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $316,223.46 | 2,499 | BLC89B2 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $310,694.80 | 2,980 | BMVBZD3 |
| 0.36% | KYMR | KYMERA THERAPEUTICS INC | -- | $286,469.46 | 3,321 | BMPRZV5 |
| 0.34% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $270,356.48 | 2,456 | BJDX8Y8 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $270,114.06 | 2,598 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $268,575.80 | 2,780 | BF2YWG4 |
| 0.30% | ALKS | ALKERMES PLC | -- | $239,610.88 | 6,784 | B3P6D26 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $237,588.29 | 8,287 | BJRFSB7 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $237,028.96 | 6,608 | BLR6XK8 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $233,750.37 | 3,437 | BRBCSP4 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $233,308.00 | 3,196 | BQBBDY8 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $224,207.76 | 3,368 | B17VCN9 |
| 0.27% | CAI | CARIS LIFE SCIENCES INC | -- | $219,727.18 | 11,486 | BT18HP9 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $215,197.56 | 3,907 | BDHF4K6 |
| 0.27% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,947.36 | 5,203 | BYTQ6X1 |
| 0.26% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $206,623.68 | 5,088 | BTZRLN8 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $198,385.74 | 3,386 | BRJ3GY4 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $195,694.94 | 4,154 | BFZQ0L8 |
| 0.24% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,812.40 | 4,869 | BLB0YQ9 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $188,608.74 | 2,231 | BM9HHL5 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $188,365.50 | 810 | 2501578 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $177,768.02 | 4,262 | BDD19F8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $174,417.72 | 12,806 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $168,073.80 | 3,755 | BLFGJD5 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $161,498.34 | 4,366 | BKY5JZ8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $149,006.76 | 6,937 | 2713317 |
| 0.18% | TWST | TWIST BIOSCIENCE CORP | -- | $148,586.88 | 2,496 | BGKG6G7 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $144,971.22 | 4,678 | BP8JSP4 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $137,486.30 | 1,970 | BKVF0J2 |
| 0.17% | ERAS | ERASCA INC | -- | $137,372.70 | 12,603 | BNLYBF3 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $134,113.98 | 4,147 | BK6L288 |
| 0.17% | VCYT | VERACYTE INC | -- | $133,332.03 | 3,237 | BFTWZY0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $131,726.14 | 6,454 | BD2B4V0 |
| 0.16% | ALMS | ALUMIS INC | -- | $131,223.00 | 5,146 | BPLQG36 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $129,585.32 | 3,173 | BQS9486 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $129,484.84 | 5,482 | BP2P6L0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $126,228.00 | 6,700 | BN15WD1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $121,913.48 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $120,084.30 | 2,334 | B72ZBG4 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $113,990.76 | 2,484 | BFXC933 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $112,164.32 | 1,732 | BMH5RL1 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $108,890.10 | 1,870 | BRXB0C0 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $108,879.12 | 4,788 | BKS3RS7 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $106,682.10 | 1,554 | BMGJZJ8 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $106,271.88 | 2,904 | BL55460 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $102,745.50 | 3,575 | BK0VHF6 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $101,982.69 | 3,933 | BJ62Z18 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $99,580.40 | 2,417 | BMFD115 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $99,477.60 | 3,435 | BMX9K07 |
| 0.12% | GRAL | GRAIL INC | -- | $99,396.00 | 1,584 | BSLSSX7 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $98,245.98 | 4,266 | B8DPDT7 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $97,725.60 | 9,695 | B9NSBM2 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $97,046.64 | 3,222 | BP9N0G0 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $95,038.36 | 4,058 | BV2DHY6 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $93,993.00 | 7,275 | BN2R582 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $90,432.81 | 6,267 | BJ5FZ74 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,154.30 | 10,210 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $87,917.94 | 5,412 | BFWLC09 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $86,040.31 | 8,861 | BNZB1X8 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $84,155.28 | 3,048 | BPCQZY9 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $83,827.44 | 591 | BNSP8K3 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $78,701.22 | 1,818 | BQKXDX4 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,526.88 | 2,608 | BMZ2X38 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $77,813.04 | 11,148 | BNC1BX1 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $77,342.72 | 2,324 | BJQ05Z6 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $77,196.90 | 2,355 | BKSGZN7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,746.78 | 913 | BCDWBX6 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $76,404.84 | 4,632 | BYSS4X4 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $76,049.44 | 1,129 | BDRW1L7 |
| 0.09% | VCEL | VERICEL CORP | -- | $76,024.26 | 2,067 | BSBMN89 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $74,408.68 | 5,218 | BJH9ZN0 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $74,154.15 | 3,591 | BN7Q7R7 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $73,413.60 | 2,172 | BMVNDH9 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $73,099.69 | 2,621 | BBC9WC7 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $72,873.78 | 21,246 | BM9FJ13 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,933.46 | 1,941 | BR3T9B6 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $71,820.32 | 4,472 | BPCK358 |
| 0.09% | ARDX | ARDELYX INC | -- | $70,865.10 | 9,981 | BN89V40 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $70,659.68 | 4,186 | BMVLGP2 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $68,581.12 | 16,768 | BF0DMK7 |
| 0.08% | INVA | INNOVIVA INC | -- | $67,875.28 | 3,014 | BDDXF67 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $66,590.80 | 4,808 | BYZM6C2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $65,814.84 | 6,396 | BK4PZ38 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $64,320.32 | 2,384 | BCBVTX1 |
| 0.08% | PGEN | PRECIGEN INC | -- | $63,377.60 | 14,404 | BKM5C84 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $63,310.95 | 3,105 | BP7KZP7 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $62,193.60 | 12,340 | BL53SR3 |
| 0.08% | NVAX | NOVAVAX INC | -- | $62,047.44 | 6,629 | BJDQXG4 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $61,645.11 | 14,783 | BWJDYK1 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $61,328.62 | 2,579 | BQB42F1 |
| 0.08% | HROW | HARROW INC | -- | $60,847.97 | 1,511 | BHNDW86 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $59,510.20 | 3,805 | BRXYZ57 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $58,651.12 | 1,826 | BQXJKH2 |
| 0.07% | QURE | UNIQURE NV | -- | $57,871.52 | 2,536 | BJFSR88 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $56,683.44 | 2,526 | BP6C0S2 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $55,863.27 | 7,663 | BYZG9R0 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,989.76 | 2,058 | BD06CS0 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,822.32 | 1,784 | BLCD809 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,942.90 | 3,362 | BYP80F1 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $51,828.26 | 1,958 | BSRK699 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $49,980.00 | 1,904 | BZ7PJQ1 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $49,820.84 | 1,682 | BMGTLY5 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $49,534.59 | 3,261 | BMZ4LN0 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $49,081.50 | 839 | BL95N25 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,998.65 | 13,445 | BPNTJ34 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,170.92 | 1,292 | BX7RSN3 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $46,221.77 | 2,219 | BQB42H3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $44,996.91 | 1,821 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $44,976.15 | 3,369 | BMGS7L1 |
| 0.06% | MNKD | MANNKIND CORP | -- | $44,649.52 | 12,542 | BF081J4 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $44,119.40 | 1,846 | BNFWZS4 |
| 0.05% | SVRA | SAVARA INC | -- | $43,661.95 | 8,285 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,022.98 | 6,754 | BLR7H87 |
| 0.05% | OMER | OMEROS CORP | -- | $42,769.72 | 2,884 | B4NB858 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $41,738.83 | 4,963 | B8K7T65 |
| 0.05% | GERN | GERON CORP | -- | $41,056.30 | 25,985 | 2370381 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,620.02 | 3,206 | BJLKVS6 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,468.52 | 10,843 | BMFJJ97 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $38,970.05 | 1,645 | B3X26D8 |
| 0.05% | XNCR | XENCOR INC | -- | $38,860.87 | 2,987 | BGCYWN8 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $37,999.80 | 4,086 | BKVDFF7 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $37,478.40 | 3,840 | BMC3HS7 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $37,352.00 | 4,025 | BMCR7V2 |
| 0.05% | ABSI | ABSCI CORP | -- | $36,419.95 | 6,121 | BN94K69 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $36,213.74 | 2,477 | BMFX8Y7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $36,065.94 | 2,406 | BM90J52 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,964.16 | 2,064 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $34,599.76 | 7,828 | BZ0QMB7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,861.52 | 3,542 | BYZD465 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $33,712.35 | 2,317 | BMFK3H6 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,659.49 | 2,129 | BQS7491 |
| 0.04% | ANNX | ANNEXON INC | -- | $33,578.70 | 5,891 | BMVV9R5 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $32,893.65 | 1,091 | BGL0JK3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,618.82 | 1,767 | BT9K6D8 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $32,432.40 | 3,276 | BFYQFJ2 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $31,989.09 | 6,623 | B3MZ6K5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $30,646.35 | 9,729 | BBNBTD2 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,947.50 | 1,210 | BKLCWZ3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $29,308.95 | 1,395 | BD9GVY0 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $28,480.48 | 6,896 | BYWVTY5 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $26,918.70 | 1,693 | BRJJYT3 |
| 0.03% | ARVN | ARVINAS INC | -- | $26,717.04 | 2,604 | BDZ30Q0 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,852.13 | 4,259 | BJQ0608 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,808.30 | 3,206 | BJ0LT31 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,762.50 | 2,290 | BLFBZ32 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $25,053.27 | 7,347 | BPBJFM7 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $25,006.80 | 1,560 | BP81RK8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,473.02 | 2,189 | B91XRN2 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $23,474.52 | 5,958 | BMCWKZ2 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $23,455.46 | 4,907 | BYV2W40 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $22,862.25 | 1,129 | BS2CR64 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,852.80 | 3,174 | BQHN6C7 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,706.88 | 2,976 | BP0TQC5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $22,200.30 | 765 | BPBPCG8 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,017.75 | 2,325 | BSMLR16 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,621.50 | 2,075 | BKLXFX5 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $21,421.36 | 2,584 | BP81R42 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,131.88 | 9,148 | BFZNYB7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $21,063.42 | 2,061 | BZ0G875 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $21,019.32 | 12,292 | B4N8MH9 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,997.72 | 4,964 | BYVQJ96 |
| 0.03% | NGNE | NEUROGENE INC | -- | $20,335.57 | 629 | BS2F741 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,208.81 | 2,199 | BRCFFK6 |
| 0.02% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,762.47 | 741 | BQD3J33 |
| 0.02% | KMDA | KAMADA LTD | -- | $19,441.44 | 2,348 | B2Q9833 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,268.10 | 2,710 | BJDX8Z9 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $18,510.66 | 1,239 | BPRBTY7 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,509.33 | 2,971 | BQ6C357 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $18,338.85 | 4,419 | BMXNGZ6 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,035.25 | 865 | BTNMG41 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $18,013.68 | 1,182 | B9L5200 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $17,982.48 | 2,417 | B12W3P6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,955.70 | 3,178 | BLN9Z50 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,401.24 | 604 | B292NQ7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,061.20 | 4,420 | BDFKQ07 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,672.16 | 2,638 | BDRJH21 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,612.96 | 5,096 | BFY7DC4 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,465.88 | 11,278 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,850.99 | 6,803 | BN4JN37 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,414.05 | 2,069 | B7F2TY6 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,607.20 | 1,240 | BM7V485 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,606.68 | 3,916 | BK5MWR1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,064.96 | 1,911 | BL5B6Z1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,882.20 | 8,166 | BFMLGR4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,705.20 | 2,916 | 2107437 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,540.71 | 2,609 | BMVBZF5 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,617.45 | 3,974 | BZ8FPH3 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,605.16 | 3,774 | BYTYP72 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,322.64 | 1,273 | BQV0J03 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,168.09 | 4,097 | BZC0D70 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,637.96 | 3,972 | BKX9NQ0 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $11,565.28 | 3,362 | BDDVW37 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,152.44 | 2,383 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,647.00 | 6,084 | BRK0149 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $10,583.94 | 1,263 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,563.41 | 1,157 | BKC9SX3 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,280.25 | 4,569 | BKRRKY7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,008.00 | 2,400 | BY7RB53 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,778.16 | 3,676 | B5LL2C2 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,702.60 | 1,884 | BKDQKM6 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,444.78 | 2,298 | BPRB2N7 |
| 0.01% | OABI | OMNIAB INC | -- | $8,376.94 | 5,858 | BN13S71 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,192.62 | 7,954 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,931.56 | 2,179 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,725.79 | 7,857 | BMYTJP4 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,554.08 | 1,523 | 2517058 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,415.85 | 3,803 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,971.93 | 8,823 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,536.76 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,493.00 | 3,020 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,830.50 | 2,535 | BLBR8D5 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $5,218.54 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,166.00 | 2,800 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,812.56 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,298.53 | 9,419 | BJ0CK86 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 38.55% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,979,061 | -- | 5,132 | -- |
| 29.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 23,705,139 | -- | 3,927 | -- |
| 26.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 21,272,450 | -- | 3,524 | -- |
| 19.83% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,930,192 | -- | 2,639 | -- |
| 16.53% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 13,286,226 | -- | 2,201 | -- |
| 4.76% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,821,073 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,629,154.64 | 28,629,155 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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