BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,861,618
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/30/2026- NAV
- NAV Change
- Market Price $81.62
- Market Price Change $+3.07
- Trading Volume (M) 19,723
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,861,618
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/30/2026- NAV
- NAV Change
- Market Price $81.62
- Market Price Change $+3.07
- Trading Volume (M) 19,723
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/30/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.93% | AMGN | AMGEN INC | -- | $3,736,383.75 | 10,791 | 2023607 |
| 4.85% | GILD | GILEAD SCIENCES INC | -- | $3,679,351.64 | 28,121 | 2369174 |
| 4.75% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,602,386.02 | 8,429 | 2931034 |
| 3.94% | REGN | REGENERON PHARMACEUTICALS | -- | $2,988,742.62 | 4,227 | 2730190 |
| 2.20% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,670,008.04 | 5,396 | B00FWN1 |
| 1.58% | INSM | INSMED INC | -- | $1,196,023.09 | 8,773 | 2614487 |
| 1.53% | RVMD | REVOLUTION MEDICINES INC | -- | $1,162,327.80 | 8,065 | BL71K91 |
| 1.49% | BIIB | BIOGEN INC | -- | $1,130,190.88 | 5,971 | 2455965 |
| 1.34% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,018,717.05 | 1,783 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $902,886.60 | 1,155 | BDVLM39 |
| 1.15% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $873,369.24 | 17,436 | BMVP7Y0 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $831,193.02 | 29,134 | BMW4NZ9 |
| 1.04% | ILMN | ILLUMINA INC | -- | $788,829.76 | 6,224 | 2613990 |
| 1.02% | INCY | INCYTE CORP | -- | $771,877.54 | 8,102 | 2471950 |
| 0.97% | MRNA | MODERNA INC | -- | $738,393.62 | 16,073 | BGSXTS3 |
| 0.92% | VTRS | VIATRIS INC | -- | $700,163.10 | 46,865 | BMWS3X9 |
| 0.89% | SMMT | SUMMIT THERAPEUTICS INC | -- | $677,277.60 | 31,560 | BMTVQS7 |
| 0.76% | ASND | ASCENDIS PHARMA A/S | -- | $574,596.90 | 2,505 | BWXJHM8 |
| 0.74% | BBIO | BRIDGEBIO PHARMA INC | -- | $561,129.01 | 7,891 | BK1KWG8 |
| 0.71% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $538,003.62 | 4,086 | 2623911 |
| 0.67% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $508,565.10 | 2,505 | B4Q5ZN4 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $502,761.00 | 6,725 | BDJ0LS6 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $483,552.30 | 1,155 | BDCBC61 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $483,242.26 | 934 | BD59BS7 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $479,697.65 | 4,637 | BK6H543 |
| 0.62% | EXEL | EXELIXIS INC | -- | $469,986.66 | 10,571 | 2576941 |
| 0.61% | GH | GUARDANT HEALTH INC | -- | $464,745.96 | 5,337 | BFXC911 |
| 0.61% | SNY | SANOFI-ADR | -- | $463,936.80 | 9,960 | 2964557 |
| 0.57% | AXSM | AXSOME THERAPEUTICS INC | -- | $432,535.50 | 2,082 | BYZR4X4 |
| 0.56% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $422,007.48 | 7,828 | 2437071 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $418,982.96 | 5,702 | BYQBFJ8 |
| 0.52% | TEM | TEMPUS AI INC-CL A | -- | $392,243.60 | 7,070 | BSLSJJ0 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $384,146.27 | 1,301 | BYYWPW6 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $361,553.22 | 1,134 | BQ721R4 |
| 0.44% | PCVX | VAXCYTE INC | -- | $335,254.68 | 5,857 | BKPVGH6 |
| 0.42% | CYTK | CYTOKINETICS INC | -- | $320,745.58 | 5,014 | BBBSBJ5 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $312,613.92 | 1,192 | BD6JX35 |
| 0.40% | HALO | HALOZYME THERAPEUTICS INC | -- | $305,822.64 | 4,804 | 2975098 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $298,834.40 | 2,980 | BMVBZD3 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $297,127.90 | 41,849 | BNSP0B8 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $293,332.62 | 2,499 | BLC89B2 |
| 0.35% | KYMR | KYMERA THERAPEUTICS INC | -- | $269,233.47 | 3,321 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $257,124.06 | 2,598 | BDCBCD8 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $238,993.36 | 2,456 | BJDX8Y8 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $237,942.20 | 3,196 | BQBBDY8 |
| 0.31% | COGT | COGENT BIOSCIENCES INC | -- | $236,500.32 | 6,608 | BLR6XK8 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $229,385.38 | 3,437 | BRBCSP4 |
| 0.30% | TERN | TERNS PHARMACEUTICALS INC | -- | $229,133.97 | 4,329 | BMDJ0C9 |
| 0.30% | ALKS | ALKERMES PLC | -- | $228,688.64 | 6,784 | B3P6D26 |
| 0.30% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $226,180.80 | 2,780 | BF2YWG4 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $224,950.62 | 8,287 | BJRFSB7 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $219,122.08 | 3,368 | B17VCN9 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $218,234.00 | 11,486 | BT18HP9 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,062.85 | 5,203 | BYTQ6X1 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,492.38 | 3,907 | BDHF4K6 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $193,617.94 | 4,154 | BFZQ0L8 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $191,935.98 | 4,869 | BLB0YQ9 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $189,751.44 | 3,386 | BRJ3GY4 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $187,136.64 | 5,088 | BTZRLN8 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $185,854.50 | 810 | 2501578 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $184,927.59 | 2,231 | BM9HHL5 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $165,280.36 | 4,262 | BDD19F8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $164,813.22 | 12,806 | BFNF1D6 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $158,160.60 | 3,755 | BLFGJD5 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $155,735.65 | 6,937 | 2713317 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $145,891.20 | 2,496 | BGKG6G7 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $135,171.36 | 4,366 | BKY5JZ8 |
| 0.18% | ORKA | ORUKA THERAPEUTICS INC | -- | $134,767.70 | 1,970 | BKVF0J2 |
| 0.18% | ERAS | ERASCA INC | -- | $134,221.95 | 12,603 | BNLYBF3 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $133,603.68 | 4,678 | BP8JSP4 |
| 0.17% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $131,520.85 | 3,173 | BQS9486 |
| 0.17% | ALMS | ALUMIS INC | -- | $127,054.74 | 5,146 | BPLQG36 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $125,778.51 | 4,147 | BK6L288 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $120,818.88 | 6,454 | BD2B4V0 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $118,520.84 | 5,482 | BP2P6L0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $117,585.00 | 6,700 | BN15WD1 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,121.68 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $112,032.00 | 2,334 | B72ZBG4 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $110,172.52 | 1,732 | BMH5RL1 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $108,004.32 | 2,484 | BFXC933 |
| 0.14% | VCYT | VERACYTE INC | -- | $106,562.04 | 3,237 | BFTWZY0 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $105,575.40 | 4,788 | BKS3RS7 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $104,032.50 | 3,575 | BK0VHF6 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $103,411.44 | 2,904 | BL55460 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $102,486.30 | 1,554 | BMGJZJ8 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $100,568.60 | 1,870 | BRXB0C0 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $99,652.91 | 2,417 | BMFD115 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $99,373.75 | 9,695 | B9NSBM2 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,105.77 | 3,933 | BJ62Z18 |
| 0.12% | RLAY | RELAY THERAPEUTICS INC | -- | $94,284.00 | 7,275 | BN2R582 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $93,523.60 | 10,210 | 2100362 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $89,074.08 | 4,266 | B8DPDT7 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $88,789.04 | 4,058 | BV2DHY6 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $88,364.70 | 6,267 | BJ5FZ74 |
| 0.11% | GRAL | GRAIL INC | -- | $86,296.32 | 1,584 | BSLSSX7 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $85,866.30 | 3,222 | BP9N0G0 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $83,941.92 | 3,048 | BPCQZY9 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $83,263.62 | 5,412 | BFWLC09 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $83,027.57 | 8,861 | BNZB1X8 |
| 0.11% | PHVS | PHARVARIS NV | -- | $80,874.08 | 2,608 | BMZ2X38 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $80,791.20 | 3,435 | BMX9K07 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $76,955.13 | 3,591 | BN7Q7R7 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $76,363.11 | 591 | BNSP8K3 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $76,041.28 | 2,324 | BJQ05Z6 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $75,477.00 | 2,172 | BMVNDH9 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $74,209.17 | 1,129 | BDRW1L7 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,617.30 | 2,355 | BKSGZN7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $73,511.16 | 21,246 | BM9FJ13 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,537.85 | 913 | BCDWBX6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $71,799.68 | 5,218 | BJH9ZN0 |
| 0.09% | VCEL | VERICEL CORP | -- | $71,786.91 | 2,067 | BSBMN89 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $71,552.00 | 4,472 | BPCK358 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $71,235.72 | 11,148 | BNC1BX1 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $70,452.72 | 4,632 | BYSS4X4 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $70,356.60 | 1,818 | BQKXDX4 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,906.20 | 4,186 | BMVLGP2 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $69,508.92 | 2,621 | BBC9WC7 |
| 0.09% | INVA | INNOVIVA INC | -- | $69,291.86 | 3,014 | BDDXF67 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $66,752.00 | 2,384 | BCBVTX1 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $65,335.14 | 6,396 | BK4PZ38 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $64,811.84 | 4,808 | BYZM6C2 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $64,305.33 | 1,941 | BR3T9B6 |
| 0.08% | ARDX | ARDELYX INC | -- | $63,179.73 | 9,981 | BN89V40 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $61,497.28 | 14,783 | BWJDYK1 |
| 0.08% | HROW | HARROW INC | -- | $61,240.83 | 1,511 | BHNDW86 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,920.64 | 14,404 | BKM5C84 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,460.75 | 3,105 | BP7KZP7 |
| 0.07% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $56,340.48 | 16,768 | BF0DMK7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $55,654.82 | 2,579 | BQB42F1 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $55,181.72 | 1,826 | BQXJKH2 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,866.28 | 2,058 | BD06CS0 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $54,100.78 | 7,663 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $52,534.83 | 6,629 | BJDQXG4 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $52,293.38 | 1,682 | BMGTLY5 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $52,043.64 | 1,958 | BSRK699 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $51,858.78 | 2,526 | BP6C0S2 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,211.00 | 12,340 | BL53SR3 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $51,068.78 | 3,362 | BYP80F1 |
| 0.07% | QURE | UNIQURE NV | -- | $50,593.20 | 2,536 | BJFSR88 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,791.44 | 1,784 | BLCD809 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $46,991.01 | 3,261 | BMZ4LN0 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $45,372.32 | 1,904 | BZ7PJQ1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $44,906.30 | 13,445 | BPNTJ34 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $44,618.02 | 839 | BL95N25 |
| 0.06% | EYPT | EYEPOINT INC | -- | $44,470.80 | 3,369 | BMGS7L1 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $43,757.50 | 3,805 | BRXYZ57 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $43,579.16 | 1,292 | BX7RSN3 |
| 0.06% | SVRA | SAVARA INC | -- | $43,413.40 | 8,285 | BYXGN81 |
| 0.06% | SEPN | SEPTERNA INC | -- | $43,266.96 | 1,821 | BQNKXX2 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $42,871.08 | 2,219 | BQB42H3 |
| 0.06% | OMER | OMEROS CORP | -- | $42,106.40 | 2,884 | B4NB858 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,931.05 | 1,645 | B3X26D8 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,368.25 | 6,754 | BLR7H87 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,895.12 | 4,963 | B8K7T65 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,538.16 | 1,846 | BNFWZS4 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $40,369.68 | 4,086 | BKVDFF7 |
| 0.05% | GERN | GERON CORP | -- | $40,016.90 | 25,985 | 2370381 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $35,907.20 | 3,206 | BJLKVS6 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $35,673.47 | 10,843 | BMFJJ97 |
| 0.05% | XNCR | XENCOR INC | -- | $35,634.91 | 2,987 | BGCYWN8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,594.49 | 2,477 | BMFX8Y7 |
| 0.05% | MNKD | MANNKIND CORP | -- | $35,493.86 | 12,542 | BF081J4 |
| 0.05% | CMPS | COMPASS PATHWAYS PLC | -- | $34,790.40 | 3,840 | BMC3HS7 |
| 0.05% | ANNX | ANNEXON INC | -- | $34,580.17 | 5,891 | BMVV9R5 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,551.36 | 2,064 | BMNDK09 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,361.43 | 2,129 | BQS7491 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $33,246.50 | 4,025 | BMCR7V2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,877.60 | 7,828 | BZ0QMB7 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,511.20 | 2,317 | BMFK3H6 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,398.30 | 2,406 | BM90J52 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,275.86 | 3,542 | BYZD465 |
| 0.04% | ABSI | ABSCI CORP | -- | $30,451.98 | 6,121 | BN94K69 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,204.72 | 3,276 | BFYQFJ2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $30,187.80 | 1,395 | BD9GVY0 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $29,773.95 | 1,767 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,632.90 | 1,210 | BKLCWZ3 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $29,101.12 | 6,896 | BYWVTY5 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,319.88 | 6,623 | B3MZ6K5 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $26,314.92 | 1,091 | BGL0JK3 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $26,271.83 | 1,129 | BS2CR64 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $26,045.12 | 7,347 | BPBJFM7 |
| 0.03% | ARVN | ARVINAS INC | -- | $25,779.60 | 2,604 | BDZ30Q0 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,333.54 | 3,206 | BJ0LT31 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,260.69 | 1,693 | BRJJYT3 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,210.34 | 2,189 | B91XRN2 |
| 0.03% | PSNL | PERSONALIS INC | -- | $23,509.68 | 4,259 | BJQ0608 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,289.30 | 2,290 | BLFBZ32 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,043.24 | 3,174 | BQHN6C7 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,925.44 | 5,958 | BMCWKZ2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,414.90 | 741 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,397.05 | 765 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,296.38 | 4,907 | BYV2W40 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,060.00 | 1,560 | BP81RK8 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,460.00 | 2,325 | BSMLR16 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,352.40 | 4,964 | BYVQJ96 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,186.82 | 2,199 | BRCFFK6 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,544.28 | 12,292 | B4N8MH9 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $19,485.24 | 9,148 | BFZNYB7 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,458.00 | 9,729 | BBNBTD2 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,322.30 | 2,710 | BJDX8Z9 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,112.72 | 2,348 | B2Q9833 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,487.17 | 2,061 | BZ0G875 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,405.25 | 2,075 | BKLXFX5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $18,391.68 | 2,976 | BP0TQC5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,217.20 | 2,584 | BP81R42 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,941.14 | 4,419 | BMXNGZ6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,510.78 | 3,178 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $17,160.70 | 2,417 | B12W3P6 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,066.45 | 865 | BTNMG41 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $16,919.85 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,809.32 | 604 | B292NQ7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $16,803.41 | 6,803 | BN4JN37 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,417.98 | 1,182 | B9L5200 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,410.61 | 629 | BS2F741 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,883.98 | 1,239 | BPRBTY7 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,789.20 | 11,278 | BM8NHS1 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,538.19 | 2,069 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,381.60 | 4,420 | BDFKQ07 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,218.82 | 2,638 | BDRJH21 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,969.41 | 1,911 | BL5B6Z1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $13,788.80 | 1,240 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,671.16 | 2,609 | BMVBZF5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,413.60 | 2,916 | 2107437 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,249.60 | 5,096 | BFY7DC4 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,605.16 | 3,774 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,413.91 | 4,097 | BZC0D70 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,922.00 | 3,974 | BZ8FPH3 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,708.84 | 3,916 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,514.06 | 8,166 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,431.54 | 1,273 | BQV0J03 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,319.25 | 2,383 | BMF7DT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,285.43 | 4,569 | BKRRKY7 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,240.76 | 3,972 | BKX9NQ0 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,799.10 | 6,084 | BRK0149 |
| 0.01% | CDXS | CODEXIS INC | -- | $10,366.32 | 3,676 | B5LL2C2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $10,141.89 | 1,263 | BP2NYN2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,973.34 | 1,157 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,169.02 | 2,298 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,952.00 | 2,400 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,892.48 | 1,884 | BKDQKM6 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $8,640.34 | 3,362 | BDDVW37 |
| 0.01% | OABI | OMNIAB INC | -- | $8,142.62 | 5,858 | BN13S71 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,799.69 | 7,954 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,735.45 | 2,179 | BP7L561 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,721.61 | 1,523 | 2517058 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,149.64 | 3,803 | BNYJR68 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,855.40 | 3,020 | BPTK6Z2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,614.02 | 7,857 | BMYTJP4 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,142.70 | 2,318 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,097.58 | 8,823 | BNNXX52 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,810.98 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,592.00 | 2,800 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,309.50 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,525.85 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,464.31 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.12% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,884,880 | -- | 4,415 | -- |
| 29.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 22,566,456 | -- | 3,849 | -- |
| 27.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,661,001 | -- | 3,524 | -- |
| 20.40% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,472,299 | -- | 2,639 | -- |
| 17.01% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,904,331 | -- | 2,201 | -- |
| 4.89% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,711,241 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,394,759.54 | 25,394,760 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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