BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,597,897
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/21/2026- NAV
- NAV Change
- Market Price $82.29
- Market Price Change $+1.14
- Trading Volume (M) 4,578
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $71,597,897
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 5/21/2026- NAV
- NAV Change
- Market Price $82.29
- Market Price Change $+1.14
- Trading Volume (M) 4,578
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 5/21/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.66% | GILD | GILEAD SCIENCES INC | -- | $3,333,231.00 | 25,542 | 2369174 |
| 4.64% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,319,615.78 | 7,657 | 2931034 |
| 4.62% | AMGN | AMGEN INC | -- | $3,307,728.26 | 9,803 | 2023607 |
| 3.45% | REGN | REGENERON PHARMACEUTICALS | -- | $2,467,545.60 | 3,840 | 2730190 |
| 2.06% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,473,701.04 | 4,904 | B00FWN1 |
| 1.57% | RVMD | REVOLUTION MEDICINES INC | -- | $1,126,225.98 | 7,326 | BL71K91 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,027,874.75 | 5,425 | 2455965 |
| 1.28% | UTHR | UNITED THERAPEUTICS CORP | -- | $916,709.40 | 1,620 | 2430412 |
| 1.22% | INSM | INSMED INC | -- | $872,735.04 | 7,968 | 2614487 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $857,031.00 | 1,050 | BDVLM39 |
| 1.18% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $848,071.35 | 15,837 | BMVP7Y0 |
| 1.14% | ILMN | ILLUMINA INC | -- | $818,723.99 | 5,653 | 2613990 |
| 1.14% | ROIV | ROIVANT SCIENCES LTD | -- | $817,084.80 | 26,460 | BMW4NZ9 |
| 1.00% | INCY | INCYTE CORP | -- | $716,840.19 | 7,359 | 2471950 |
| 0.97% | VTRS | VIATRIS INC | -- | $695,512.10 | 42,565 | BMWS3X9 |
| 0.96% | MRNA | MODERNA INC | -- | $689,996.00 | 14,600 | BGSXTS3 |
| 0.81% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $577,216.00 | 3,712 | 2623911 |
| 0.80% | GH | GUARDANT HEALTH INC | -- | $572,348.50 | 4,850 | BFXC911 |
| 0.79% | ASND | ASCENDIS PHARMA A/S | -- | $563,332.76 | 2,276 | BWXJHM8 |
| 0.76% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $544,635.00 | 2,275 | B4Q5ZN4 |
| 0.70% | BBIO | BRIDGEBIO PHARMA INC | -- | $503,696.76 | 7,167 | BK1KWG8 |
| 0.70% | SMMT | SUMMIT THERAPEUTICS INC | -- | $500,760.08 | 28,664 | BMTVQS7 |
| 0.67% | EXEL | EXELIXIS INC | -- | $476,640.00 | 9,600 | 2576941 |
| 0.65% | IONS | IONIS PHARMACEUTICALS INC | -- | $462,940.02 | 6,109 | BDJ0LS6 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $452,035.10 | 1,051 | BDCBC61 |
| 0.62% | AXSM | AXSOME THERAPEUTICS INC | -- | $441,579.60 | 1,890 | BYZR4X4 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $435,010.73 | 847 | BD59BS7 |
| 0.57% | SNY | SANOFI-ADR | -- | $406,391.24 | 9,047 | 2964557 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $391,146.12 | 5,178 | BYQBFJ8 |
| 0.54% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $384,651.00 | 7,110 | 2437071 |
| 0.54% | BNTX | BIONTECH SE-ADR | -- | $383,088.09 | 4,213 | BK6H543 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $365,661.22 | 1,181 | BYYWPW6 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $360,726.24 | 1,029 | BQ721R4 |
| 0.50% | CYTK | CYTOKINETICS INC | -- | $355,407.18 | 4,553 | BBBSBJ5 |
| 0.46% | KRYS | KRYSTAL BIOTECH INC | -- | $328,568.40 | 1,080 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $299,021.28 | 4,364 | 2975098 |
| 0.42% | TEM | TEMPUS AI INC-CL A | -- | $298,651.76 | 6,424 | BSLSJJ0 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $294,181.92 | 38,008 | BNSP0B8 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $281,672.13 | 2,271 | BLC89B2 |
| 0.38% | NUVL | NUVALENT INC-A | -- | $273,854.20 | 2,705 | BMVBZD3 |
| 0.36% | IMVT | IMMUNOVANT INC | -- | $256,759.99 | 7,523 | BJRFSB7 |
| 0.35% | PCVX | VAXCYTE INC | -- | $252,162.19 | 5,321 | BKPVGH6 |
| 0.34% | KYMR | KYMERA THERAPEUTICS INC | -- | $243,200.37 | 3,017 | BMPRZV5 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $240,845.61 | 2,361 | BDCBCD8 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $227,819.94 | 2,526 | BF2YWG4 |
| 0.32% | ALKS | ALKERMES PLC | -- | $227,722.85 | 6,163 | B3P6D26 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $224,594.77 | 2,231 | BJDX8Y8 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $215,899.60 | 2,905 | BQBBDY8 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $213,696.98 | 3,062 | B17VCN9 |
| 0.28% | CGON | CG ONCOLOGY INC | -- | $201,714.57 | 3,123 | BRBCSP4 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $195,545.16 | 6,002 | BLR6XK8 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $180,047.56 | 3,773 | BFZQ0L8 |
| 0.25% | CRSP | CRISPR THERAPEUTICS AG | -- | $177,145.00 | 3,550 | BDHF4K6 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,079.63 | 4,423 | BLB0YQ9 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,215.04 | 4,624 | BTZRLN8 |
| 0.23% | APGE | APOGEE THERAPEUTICS INC | -- | $167,168.04 | 2,028 | BM9HHL5 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $166,364.88 | 3,074 | BRJ3GY4 |
| 0.23% | CAI | CARIS LIFE SCIENCES INC | -- | $166,270.14 | 10,431 | BT18HP9 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $163,524.48 | 736 | 2501578 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $152,518.66 | 3,409 | BLFGJD5 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $151,966.48 | 4,252 | BP8JSP4 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $144,469.44 | 11,632 | BFNF1D6 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $143,612.48 | 3,872 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $134,379.96 | 6,303 | 2713317 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $133,320.11 | 2,266 | BGKG6G7 |
| 0.19% | ERAS | ERASCA INC | -- | $132,807.62 | 11,444 | BNLYBF3 |
| 0.19% | VCYT | VERACYTE INC | -- | $132,768.22 | 2,938 | BFTWZY0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $129,648.54 | 3,966 | BKY5JZ8 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $113,155.90 | 5,863 | BD2B4V0 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $111,715.20 | 2,880 | BQS9486 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $107,624.36 | 4,978 | BP2P6L0 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $107,382.68 | 4,351 | BKS3RS7 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $105,731.19 | 6,087 | BN15WD1 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $104,996.41 | 1,789 | BKVF0J2 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $104,685.60 | 2,120 | B72ZBG4 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $104,232.89 | 3,767 | BK6L288 |
| 0.14% | ALMS | ALUMIS INC | -- | $103,622.58 | 4,674 | BPLQG36 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $99,854.04 | 1,573 | BMH5RL1 |
| 0.14% | GRAL | GRAIL INC | -- | $97,650.54 | 1,439 | BSLSSX7 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $96,372.87 | 4,587 | BKX9VD3 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $95,886.84 | 3,246 | BK0VHF6 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $94,720.43 | 1,411 | BMGJZJ8 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $92,781.00 | 2,196 | BMFD115 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $91,097.70 | 1,698 | BRXB0C0 |
| 0.13% | VERA | VERA THERAPEUTICS INC | -- | $90,546.60 | 2,636 | BL55460 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $90,237.96 | 6,606 | BN2R582 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $88,422.75 | 2,925 | BP9N0G0 |
| 0.12% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $87,384.78 | 3,122 | BMX9K07 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $84,668.41 | 3,571 | BJ62Z18 |
| 0.12% | KOD | KODIAK SCIENCES INC | -- | $84,359.55 | 2,255 | BFXC933 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $83,465.25 | 3,685 | BV2DHY6 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $78,948.04 | 5,692 | BJ5FZ74 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $77,598.27 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $75,921.30 | 4,914 | BFWLC09 |
| 0.11% | NVCR | NOVOCURE LTD | -- | $75,341.10 | 4,209 | BYSS4X4 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $74,490.30 | 8,805 | B9NSBM2 |
| 0.10% | PHVS | PHARVARIS NV | -- | $72,288.18 | 2,367 | BMZ2X38 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $69,454.26 | 2,766 | BPCQZY9 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $68,929.25 | 1,651 | BQKXDX4 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,699.10 | 830 | BCDWBX6 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $67,146.72 | 4,742 | BJH9ZN0 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $66,649.06 | 3,802 | BMVLGP2 |
| 0.09% | OCUL | OCULAR THERAPEUTIX INC | -- | $66,162.78 | 8,049 | BNZB1X8 |
| 0.09% | VCEL | VERICEL CORP | -- | $65,906.25 | 1,875 | BSBMN89 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,720.00 | 3,875 | B8DPDT7 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,248.60 | 2,140 | BKSGZN7 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $65,181.48 | 1,974 | BMVNDH9 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $64,738.80 | 1,764 | BR3T9B6 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $64,469.97 | 3,261 | BN7Q7R7 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $64,351.95 | 2,379 | BBC9WC7 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $62,633.37 | 2,111 | BJQ05Z6 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,359.14 | 2,166 | BCBVTX1 |
| 0.09% | ANAB | ANAPTYSBIO INC | -- | $61,799.43 | 1,023 | BDRW1L7 |
| 0.08% | INVA | INNOVIVA INC | -- | $60,828.00 | 2,740 | BDDXF67 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,013.67 | 19,297 | BM9FJ13 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $59,376.09 | 537 | BNSP8K3 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $58,147.57 | 13,429 | BWJDYK1 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $57,614.26 | 11,209 | BL53SR3 |
| 0.08% | ARDX | ARDELYX INC | -- | $57,569.10 | 9,066 | BN89V40 |
| 0.08% | QURE | UNIQURE NV | -- | $57,071.80 | 2,305 | BJFSR88 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $56,541.87 | 4,059 | BPCK358 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $56,358.40 | 15,232 | BF0DMK7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $56,109.12 | 10,128 | BNC1BX1 |
| 0.08% | PGEN | PRECIGEN INC | -- | $55,982.40 | 13,080 | BKM5C84 |
| 0.08% | NVAX | NOVAVAX INC | -- | $54,086.54 | 6,023 | BJDQXG4 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $54,044.53 | 4,369 | BYZM6C2 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $53,203.84 | 2,818 | BP7KZP7 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,707.82 | 1,658 | BQXJKH2 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $52,464.30 | 5,810 | BK4PZ38 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $51,692.40 | 1,730 | BZ7PJQ1 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,059.90 | 1,870 | BD06CS0 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $49,940.38 | 2,294 | BP6C0S2 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $48,828.12 | 2,343 | BQB42F1 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $48,630.00 | 1,621 | BLCD809 |
| 0.06% | SEPN | SEPTERNA INC | -- | $46,263.44 | 1,657 | BQNKXX2 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $45,783.50 | 1,778 | BSRK699 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $45,398.70 | 3,455 | BRXYZ57 |
| 0.06% | HROW | HARROW INC | -- | $45,155.20 | 1,370 | BHNDW86 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $44,683.20 | 6,960 | BYZG9R0 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $41,645.72 | 2,962 | BMZ4LN0 |
| 0.06% | ALVO | ALVOTECH SA | -- | $41,269.80 | 12,210 | BPNTJ34 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $41,229.00 | 1,527 | BMGTLY5 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $40,414.33 | 3,487 | BMC3HS7 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $40,340.24 | 1,172 | BX7RSN3 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $39,946.32 | 3,054 | BYP80F1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $39,342.72 | 1,983 | BQB42H3 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $39,134.92 | 6,134 | BLR7H87 |
| 0.05% | EYPT | EYEPOINT INC | -- | $39,132.36 | 3,062 | BMGS7L1 |
| 0.05% | SVRA | SAVARA INC | -- | $38,071.44 | 7,524 | BYXGN81 |
| 0.05% | MNKD | MANNKIND CORP | -- | $37,697.59 | 11,389 | BF081J4 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $36,576.10 | 4,510 | B8K7T65 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $35,816.34 | 3,218 | BYZD465 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $35,102.60 | 1,495 | B3X26D8 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $34,720.00 | 992 | BGL0JK3 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $33,720.96 | 2,912 | BJLKVS6 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $32,436.91 | 2,251 | BMFX8Y7 |
| 0.04% | PSNL | PERSONALIS INC | -- | $31,919.25 | 3,869 | BJQ0608 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $31,568.40 | 7,110 | BZ0QMB7 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $31,395.06 | 3,711 | BKVDFF7 |
| 0.04% | OMER | OMEROS CORP | -- | $31,359.12 | 2,622 | B4NB858 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,024.35 | 9,849 | BMFJJ97 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,637.50 | 1,875 | BMNDK09 |
| 0.04% | XNCR | XENCOR INC | -- | $30,552.97 | 2,711 | BGCYWN8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,546.30 | 2,185 | BM90J52 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,454.32 | 1,677 | BNFWZS4 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $30,088.88 | 3,656 | BMCR7V2 |
| 0.04% | GERN | GERON CORP | -- | $29,738.52 | 23,602 | 2370381 |
| 0.04% | ANNX | ANNEXON INC | -- | $29,098.56 | 5,349 | BMVV9R5 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,971.32 | 1,934 | BQS7491 |
| 0.04% | ABSI | ABSCI CORP | -- | $28,305.49 | 5,561 | BN94K69 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $28,232.75 | 2,975 | BFYQFJ2 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,659.81 | 8,837 | BBNBTD2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,850.96 | 1,604 | BT9K6D8 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $25,529.98 | 763 | BL95N25 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $24,237.90 | 1,269 | BD9GVY0 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,236.80 | 5,410 | BMCWKZ2 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $23,556.40 | 6,265 | BYWVTY5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,462.66 | 2,911 | BJ0LT31 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $23,207.80 | 6,028 | B3MZ6K5 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $23,176.05 | 2,105 | BMFK3H6 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,101.44 | 1,536 | BRJJYT3 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,594.00 | 1,100 | BKLCWZ3 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $21,850.67 | 2,083 | BLFBZ32 |
| 0.03% | ARVN | ARVINAS INC | -- | $21,503.30 | 2,363 | BDZ30Q0 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $21,466.51 | 2,707 | BP0TQC5 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,243.86 | 4,459 | BYV2W40 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,764.36 | 693 | BPBPCG8 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,685.35 | 6,673 | BPBJFM7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $19,615.68 | 672 | BQD3J33 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,081.53 | 4,511 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $18,796.80 | 2,112 | BSMLR16 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $18,720.00 | 2,880 | BQHN6C7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $18,716.49 | 1,989 | B91XRN2 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $17,969.85 | 2,349 | BP81R42 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $17,145.48 | 1,023 | BS2CR64 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $16,894.62 | 1,997 | BRCFFK6 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,687.88 | 2,134 | B2Q9833 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,380.65 | 1,885 | BKLXFX5 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,283.68 | 8,308 | BFZNYB7 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $16,237.76 | 2,464 | BJDX8Z9 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,151.88 | 1,124 | BPRBTY7 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $15,936.66 | 3,053 | BDDVW37 |
| 0.02% | NGNE | NEUROGENE INC | -- | $15,765.31 | 571 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,460.65 | 2,397 | BDRJH21 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,217.96 | 548 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $14,825.76 | 1,072 | B9L5200 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,329.98 | 4,014 | BMXNGZ6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $14,105.31 | 2,697 | BQ6C357 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,953.75 | 11,163 | B4N8MH9 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $13,615.10 | 787 | BTNMG41 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,575.06 | 2,186 | B12W3P6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,571.10 | 5,322 | BN13S71 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,568.83 | 4,631 | BFY7DC4 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,246.95 | 1,879 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,125.33 | 3,557 | BK5MWR1 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,703.68 | 3,609 | BKX9NQ0 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,642.75 | 1,873 | BZ0G875 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $12,622.50 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,480.43 | 4,013 | BDFKQ07 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $12,462.66 | 2,646 | 2107437 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $12,460.14 | 2,387 | BMVBZF5 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,249.36 | 2,889 | BLN9Z50 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,233.10 | 7,414 | BFMLGR4 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $11,425.60 | 6,176 | BN4JN37 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,370.84 | 10,244 | BM8NHS1 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,266.64 | 1,736 | BL5B6Z1 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $10,604.85 | 3,721 | BZC0D70 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,641.37 | 3,611 | BZ8FPH3 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,284.46 | 3,426 | BYTYP72 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,006.40 | 2,165 | BMF7DT9 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,934.96 | 1,416 | BP81RK8 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,708.16 | 1,158 | BQV0J03 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,674.25 | 5,525 | BRK0149 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,564.90 | 2,089 | BPRB2N7 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,452.73 | 3,341 | B5LL2C2 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,029.00 | 1,147 | BP2NYN2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,018.72 | 2,179 | BY7RB53 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,666.47 | 1,981 | BP7L561 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,613.95 | 1,711 | BKDQKM6 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $7,472.75 | 2,105 | BKTV702 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,388.78 | 4,151 | BKRRKY7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,385.04 | 1,052 | BKC9SX3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,278.72 | 7,136 | BMYTJP4 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,157.70 | 7,230 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,907.26 | 1,387 | 2517058 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,873.46 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,329.48 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,705.44 | 2,743 | BPTK6Z2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,467.82 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,913.14 | 2,541 | BMTX3D7 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,860.56 | 3,608 | BNNXX18 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $3,626.04 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,718.70 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 31.55% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 22,585,270 | -- | 3,827 | -- |
| 29.05% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,797,097 | -- | 3,524 | -- |
| 27.81% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,911,863 | -- | 3,374 | -- |
| 21.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,574,217 | -- | 2,639 | -- |
| 20.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,830,620 | -- | 2,513 | -- |
| 5.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,735,687 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,005,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $20,852,131.34 | 20,852,131 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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