BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,134,340
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/10/2026- NAV
- NAV Change
- Market Price $81.57
- Market Price Change $-2.80
- Trading Volume (M) 11,768
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,134,340
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/10/2026- NAV
- NAV Change
- Market Price $81.57
- Market Price Change $-2.80
- Trading Volume (M) 11,768
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/10/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.27% | GILD | GILEAD SCIENCES INC | -- | $4,168,727.07 | 29,993 | 2369174 |
| 5.11% | AMGN | AMGEN INC | -- | $4,040,240.20 | 11,510 | 2023607 |
| 4.96% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,922,503.57 | 8,991 | 2931034 |
| 4.27% | REGN | REGENERON PHARMACEUTICALS | -- | $3,376,654.83 | 4,509 | 2730190 |
| 2.34% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,854,065.16 | 5,756 | B00FWN1 |
| 1.83% | INSM | INSMED INC | -- | $1,448,711.98 | 9,358 | 2614487 |
| 1.39% | BIIB | BIOGEN INC | -- | $1,101,818.90 | 6,370 | 2455965 |
| 1.37% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,087,430.46 | 1,902 | 2430412 |
| 1.24% | ARGX | ARGENX SE - ADR | -- | $984,369.15 | 1,231 | BDVLM39 |
| 1.13% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $890,892.10 | 18,599 | BMVP7Y0 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $876,569.33 | 31,073 | BMW4NZ9 |
| 1.10% | MRNA | MODERNA INC | -- | $873,709.20 | 17,145 | BGSXTS3 |
| 1.05% | INCY | INCYTE CORP | -- | $830,044.80 | 8,640 | 2471950 |
| 1.05% | RVMD | REVOLUTION MEDICINES INC | -- | $829,587.29 | 8,603 | BL71K91 |
| 1.01% | ILMN | ILLUMINA INC | -- | $802,854.27 | 6,639 | 2613990 |
| 0.85% | VTRS | VIATRIS INC | -- | $673,324.89 | 49,987 | BMWS3X9 |
| 0.84% | SMMT | SUMMIT THERAPEUTICS INC | -- | $662,131.54 | 33,662 | BMTVQS7 |
| 0.81% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $639,356.16 | 2,672 | BV9G6B8 |
| 0.79% | BBIO | BRIDGEBIO PHARMA INC | -- | $627,824.03 | 8,417 | BK1KWG8 |
| 0.77% | MEDP | MEDPACE HOLDINGS INC | -- | $607,535.43 | 1,231 | BDCBC61 |
| 0.71% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $561,702.62 | 4,358 | 2623911 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $539,119.24 | 7,172 | BDJ0LS6 |
| 0.66% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $518,902.40 | 2,672 | B4Q5ZN4 |
| 0.65% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $518,051.17 | 997 | BD59BS7 |
| 0.63% | EXEL | EXELIXIS INC | -- | $499,144.25 | 11,275 | 2576941 |
| 0.63% | SNY | SANOFI-ADR | -- | $496,825.00 | 10,625 | 2964557 |
| 0.60% | BNTX | BIONTECH SE-ADR | -- | $472,343.00 | 4,946 | BK6H543 |
| 0.58% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $455,325.50 | 8,350 | 2437071 |
| 0.57% | GH | GUARDANT HEALTH INC | -- | $447,469.80 | 5,693 | BFXC911 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $429,808.08 | 1,388 | BYYWPW6 |
| 0.50% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $396,116.34 | 6,081 | BYQBFJ8 |
| 0.50% | AXSM | AXSOME THERAPEUTICS INC | -- | $395,582.31 | 2,221 | BYZR4X4 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $382,213.26 | 1,209 | BQ721R4 |
| 0.48% | PCVX | VAXCYTE INC | -- | $380,378.24 | 6,248 | BKPVGH6 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $347,608.47 | 5,347 | BBBSBJ5 |
| 0.44% | HALO | HALOZYME THERAPEUTICS INC | -- | $347,509.68 | 5,124 | 2975098 |
| 0.42% | ABVX | ABIVAX SA-ADR | -- | $336,289.24 | 2,666 | BLC89B2 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $329,189.00 | 1,271 | BD6JX35 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $326,507.72 | 3,178 | BMVBZD3 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $324,942.80 | 44,635 | BNSP0B8 |
| 0.41% | TEM | TEMPUS AI INC-CL A | -- | $323,810.54 | 7,541 | BSLSJJ0 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $301,332.15 | 3,543 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $273,830.22 | 2,771 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $256,299.39 | 7,047 | BLR6XK8 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $250,216.35 | 2,965 | BF2YWG4 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $249,328.80 | 2,619 | BJDX8Y8 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $248,188.20 | 3,666 | BRBCSP4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $246,803.17 | 3,593 | B17VCN9 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $242,992.71 | 4,617 | BMDJ0C9 |
| 0.31% | ALKS | ALKERMES PLC | -- | $241,359.60 | 7,235 | B3P6D26 |
| 0.29% | ERAS | ERASCA INC | -- | $228,648.42 | 13,442 | BNLYBF3 |
| 0.29% | APLS | APELLIS PHARMACEUTICALS INC | -- | $226,384.50 | 5,550 | BYTQ6X1 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $221,322.80 | 4,430 | BFZQ0L8 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $221,112.50 | 12,250 | BT18HP9 |
| 0.27% | IMVT | IMMUNOVANT INC | -- | $216,531.00 | 8,838 | BJRFSB7 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $213,433.74 | 4,167 | BDHF4K6 |
| 0.27% | XENE | XENON PHARMACEUTICALS INC | -- | $210,940.80 | 3,612 | BRJ3GY4 |
| 0.26% | APGE | APOGEE THERAPEUTICS INC | -- | $205,322.60 | 2,380 | BM9HHL5 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $205,019.64 | 5,193 | BLB0YQ9 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $184,407.33 | 3,383 | BQS9486 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $179,294.24 | 4,546 | BDD19F8 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $177,255.80 | 865 | 2501578 |
| 0.22% | SYRE | SPYRE THERAPEUTICS INC | -- | $174,847.61 | 3,409 | BQBBDY8 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $173,452.40 | 4,990 | BP8JSP4 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $171,296.40 | 13,660 | BFNF1D6 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $165,771.12 | 5,428 | BTZRLN8 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $160,876.00 | 7,400 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $152,809.92 | 4,656 | BKY5JZ8 |
| 0.18% | VERA | VERA THERAPEUTICS INC | -- | $139,533.92 | 3,098 | BL55460 |
| 0.17% | TARS | TARSUS PHARMACEUTICALS INC | -- | $134,018.32 | 1,847 | BMH5RL1 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $133,505.96 | 7,147 | BN15WD1 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $132,398.55 | 6,885 | BD2B4V0 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $130,249.80 | 5,380 | BKX9VD3 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $127,536.42 | 2,662 | BGKG6G7 |
| 0.16% | ALMS | ALUMIS INC | -- | $126,521.45 | 5,489 | BPLQG36 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $126,142.52 | 2,489 | B72ZBG4 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $125,177.58 | 2,101 | BKVF0J2 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $121,322.89 | 4,423 | BK6L288 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $118,863.16 | 5,108 | BKS3RS7 |
| 0.15% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $116,834.96 | 2,578 | BMFD115 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $116,647.65 | 5,847 | BP2P6L0 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $116,296.50 | 3,813 | BK0VHF6 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $115,984.80 | 4,005 | BLFGJD5 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $115,919.46 | 7,759 | BN2R582 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $114,241.50 | 2,650 | BFXC933 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $109,892.24 | 1,657 | BMGJZJ8 |
| 0.14% | VCYT | VERACYTE INC | -- | $107,291.59 | 3,451 | BFTWZY0 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $104,108.40 | 10,890 | 2100362 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $100,298.00 | 10,340 | B9NSBM2 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $97,743.50 | 4,195 | BJ62Z18 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $96,369.00 | 4,550 | B8DPDT7 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $96,292.95 | 4,485 | BLB0YH0 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $93,830.44 | 1,993 | BRXB0C0 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $93,580.76 | 3,829 | BN7Q7R7 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $93,181.84 | 4,328 | BV2DHY6 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $91,466.32 | 3,436 | BP9N0G0 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $90,966.72 | 5,772 | BFWLC09 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $85,540.00 | 3,250 | BPCQZY9 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $85,488.36 | 6,684 | BJ5FZ74 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $85,104.07 | 2,479 | BJQ05Z6 |
| 0.11% | ANAB | ANAPTYSBIO INC | -- | $84,400.40 | 1,204 | BDRW1L7 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $83,715.56 | 2,543 | BCBVTX1 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $83,074.29 | 9,451 | BNZB1X8 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $81,697.42 | 2,317 | BMVNDH9 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $78,958.75 | 2,795 | BBC9WC7 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $78,020.84 | 4,769 | BPCK358 |
| 0.10% | GRAL | GRAIL INC | -- | $77,160.33 | 1,691 | BSLSSX7 |
| 0.10% | INVA | INNOVIVA INC | -- | $76,388.40 | 3,215 | BDDXF67 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,244.28 | 973 | BCDWBX6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $74,328.08 | 22,661 | BM9FJ13 |
| 0.09% | VCEL | VERICEL CORP | -- | $74,308.50 | 2,205 | BSBMN89 |
| 0.09% | PHVS | PHARVARIS NV | -- | $74,084.66 | 2,782 | BMZ2X38 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $73,468.71 | 1,939 | BQKXDX4 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $73,415.54 | 5,566 | BJH9ZN0 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,571.68 | 2,512 | BKSGZN7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,557.92 | 4,464 | BMVLGP2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $70,731.90 | 2,070 | BR3T9B6 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,176.72 | 5,128 | BYZM6C2 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $66,538.24 | 3,664 | BMX9K07 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $66,170.80 | 17,884 | BF0DMK7 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,792.28 | 10,646 | BN89V40 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,818.50 | 6,823 | BK4PZ38 |
| 0.08% | PGEN | PRECIGEN INC | -- | $63,905.92 | 15,362 | BKM5C84 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $60,419.00 | 1,949 | BQXJKH2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,088.15 | 1,903 | BLCD809 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $58,682.14 | 8,173 | BYZG9R0 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $58,080.00 | 2,750 | BQB42F1 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $57,876.28 | 3,311 | BP7KZP7 |
| 0.07% | HROW | HARROW INC | -- | $57,847.30 | 1,610 | BHNDW86 |
| 0.07% | NVAX | NOVAVAX INC | -- | $57,424.64 | 7,072 | BJDQXG4 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $57,395.52 | 15,768 | BWJDYK1 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,011.90 | 3,479 | BMZ4LN0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $55,755.41 | 2,089 | BSRK699 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $54,148.60 | 3,586 | BYP80F1 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $53,390.59 | 11,891 | BNC1BX1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $52,265.20 | 4,940 | BYSS4X4 |
| 0.07% | ALVO | ALVOTECH SA | -- | $51,910.80 | 14,340 | BPNTJ34 |
| 0.07% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $51,811.55 | 895 | BL95N25 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,998.86 | 3,594 | BMGS7L1 |
| 0.06% | SVRA | SAVARA INC | -- | $50,006.10 | 8,835 | BYXGN81 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,913.13 | 1,379 | BX7RSN3 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $48,340.60 | 2,365 | BQB42H3 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $47,495.37 | 631 | BNSP8K3 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,593.48 | 13,162 | BL53SR3 |
| 0.06% | GERN | GERON CORP | -- | $46,282.38 | 27,714 | 2370381 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,649.78 | 1,793 | BMGTLY5 |
| 0.06% | SEPN | SEPTERNA INC | -- | $44,863.87 | 1,943 | BQNKXX2 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $44,233.70 | 4,358 | BKVDFF7 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $43,808.67 | 2,031 | BZ7PJQ1 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $43,471.95 | 5,295 | B8K7T65 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $43,194.60 | 3,420 | BJLKVS6 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $42,561.05 | 2,195 | BD06CS0 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $42,333.96 | 2,693 | BP6C0S2 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $42,143.40 | 7,204 | BLR7H87 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,775.24 | 1,756 | B3X26D8 |
| 0.05% | QURE | UNIQURE NV | -- | $41,602.90 | 2,705 | BJFSR88 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,108.53 | 1,969 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $39,557.70 | 3,185 | BGCYWN8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,445.06 | 2,642 | BMFX8Y7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $37,295.10 | 2,565 | BM90J52 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $37,261.62 | 4,059 | BRXYZ57 |
| 0.05% | ANNX | ANNEXON INC | -- | $36,755.55 | 6,283 | BMVV9R5 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $35,986.35 | 2,201 | BMNDK09 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $35,732.76 | 11,564 | BMFJJ97 |
| 0.04% | OMER | OMEROS CORP | -- | $35,354.73 | 3,077 | B4NB858 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $34,652.50 | 8,350 | BZ0QMB7 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,558.65 | 4,293 | BMCR7V2 |
| 0.04% | MNKD | MANNKIND CORP | -- | $34,378.89 | 13,377 | BF081J4 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,080.00 | 2,272 | BQS7491 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,755.26 | 3,778 | BYZD465 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,288.45 | 7,355 | BYWVTY5 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $31,341.18 | 3,494 | BFYQFJ2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $30,751.16 | 1,487 | BD9GVY0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,656.68 | 1,163 | BGL0JK3 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,534.34 | 1,886 | BT9K6D8 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $30,059.52 | 2,472 | BMFK3H6 |
| 0.04% | ARVN | ARVINAS INC | -- | $30,057.96 | 2,778 | BDZ30Q0 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,837.70 | 1,290 | BKLCWZ3 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $27,907.88 | 1,804 | BRJJYT3 |
| 0.03% | PSNL | PERSONALIS INC | -- | $27,348.86 | 4,543 | BJQ0608 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,139.68 | 3,384 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $26,880.91 | 7,837 | BPBJFM7 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $26,539.04 | 9,757 | BFZNYB7 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,649.58 | 7,066 | B3MZ6K5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,067.52 | 816 | BPBPCG8 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,760.80 | 3,420 | BJ0LT31 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $24,609.54 | 2,346 | BRCFFK6 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,528.00 | 2,336 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,135.21 | 2,443 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,038.80 | 789 | BQD3J33 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,858.05 | 4,713 | BMXNGZ6 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $22,650.88 | 4,096 | BMC3HS7 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $22,520.26 | 10,378 | BBNBTD2 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $22,450.50 | 1,663 | BP81RK8 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $22,196.00 | 2,480 | BSMLR16 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $21,827.05 | 2,891 | BJDX8Z9 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,719.34 | 2,214 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,607.68 | 5,296 | BYVQJ96 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,267.45 | 2,505 | B2Q9833 |
| 0.03% | IVVD | INVIVYD INC | -- | $21,172.80 | 12,030 | BM8NHS1 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,149.40 | 5,235 | BYV2W40 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $20,665.97 | 923 | BTNMG41 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $19,509.85 | 6,355 | BMCWKZ2 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,453.44 | 6,528 | BN94K69 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,342.40 | 2,198 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $19,226.97 | 3,391 | BLN9Z50 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,950.62 | 3,169 | BQ6C357 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,747.60 | 2,757 | BP81R42 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $18,598.72 | 2,576 | B12W3P6 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $18,289.60 | 644 | B292NQ7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,792.71 | 1,261 | B9L5200 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $17,612.64 | 5,436 | BFY7DC4 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,568.74 | 13,111 | B4N8MH9 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,178.24 | 2,208 | B7F2TY6 |
| 0.02% | REPL | REPLIMUNE GROUP INC | -- | $17,069.36 | 3,586 | BDDVW37 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,014.14 | 1,322 | BPRBTY7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,451.86 | 4,714 | BDFKQ07 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,367.68 | 2,784 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,330.42 | 3,174 | BP0TQC5 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,824.22 | 1,323 | BM7V485 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $14,800.20 | 7,255 | BN4JN37 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,330.32 | 4,369 | BZC0D70 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,695.36 | 672 | BS2F741 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,559.60 | 3,110 | 2107437 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,077.14 | 4,178 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,976.41 | 8,709 | BFMLGR4 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,459.72 | 4,238 | BZ8FPH3 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,307.99 | 1,357 | BQV0J03 |
| 0.02% | EOLS | EVOLUS INC | -- | $12,011.51 | 2,813 | BDRJH21 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $11,870.80 | 4,024 | BYTYP72 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,677.74 | 2,038 | BL5B6Z1 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,667.78 | 2,542 | BMF7DT9 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,500.28 | 4,873 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,901.52 | 6,489 | BRK0149 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $10,738.26 | 4,236 | BKX9NQ0 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,307.88 | 1,233 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,122.63 | 2,451 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,934.34 | 2,011 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,570.66 | 2,559 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $9,186.03 | 6,249 | BN13S71 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,783.04 | 3,921 | B5LL2C2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,022.78 | 3,222 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,830.01 | 4,057 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,718.75 | 1,625 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,133.80 | 1,346 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,553.68 | 2,324 | BP7L561 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,492.90 | 9,410 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,330.88 | 2,473 | BKTV702 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,282.40 | 8,484 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,407.81 | 8,379 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,897.04 | 2,986 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,596.80 | 2,704 | BLBR8D5 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,114.66 | 10,048 | BJ0CK86 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,723.30 | 945 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,133.90 | 4,235 | BNNXX18 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $25.86 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.97% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 27,672,139 | -- | 4,731 | -- |
| 30.54% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,168,523 | -- | 4,132 | -- |
| 27.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,653,405 | -- | 3,702 | -- |
| 19.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,435,801 | -- | 2,639 | -- |
| 14.71% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,639,729 | -- | 1,990 | -- |
| 4.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,702,487 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,336,354.41 | 25,336,354 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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