BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $66,617,909
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/02/2026- NAV
- NAV Change
- Market Price $76.69
- Market Price Change $-4.77
- Trading Volume (M) 6,907
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $66,617,909
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/02/2026- NAV
- NAV Change
- Market Price $76.69
- Market Price Change $-4.77
- Trading Volume (M) 6,907
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/02/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.89% | GILD | GILEAD SCIENCES INC | -- | $3,258,392.94 | 25,542 | 2369174 |
| 4.89% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,254,914.13 | 7,657 | 2931034 |
| 4.83% | AMGN | AMGEN INC | -- | $3,217,932.78 | 9,803 | 2023607 |
| 3.48% | REGN | REGENERON PHARMACEUTICALS | -- | $2,315,212.80 | 3,840 | 2730190 |
| 2.11% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,403,132.48 | 4,904 | B00FWN1 |
| 1.66% | RVMD | REVOLUTION MEDICINES INC | -- | $1,108,497.06 | 7,326 | BL71K91 |
| 1.54% | BIIB | BIOGEN INC | -- | $1,024,402.75 | 5,425 | 2455965 |
| 1.38% | ILMN | ILLUMINA INC | -- | $918,895.15 | 5,653 | 2613990 |
| 1.31% | UTHR | UNITED THERAPEUTICS CORP | -- | $874,881.00 | 1,620 | 2430412 |
| 1.28% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $855,356.37 | 15,837 | BMVP7Y0 |
| 1.26% | ARGX | ARGENX SE - ADR | -- | $842,278.50 | 1,050 | BDVLM39 |
| 1.24% | INSM | INSMED INC | -- | $826,520.64 | 7,968 | 2614487 |
| 1.12% | ROIV | ROIVANT SCIENCES LTD | -- | $747,495.00 | 26,460 | BMW4NZ9 |
| 1.02% | INCY | INCYTE CORP | -- | $678,794.16 | 7,359 | 2471950 |
| 1.00% | VTRS | VIATRIS INC | -- | $667,844.85 | 42,565 | BMWS3X9 |
| 1.00% | MRNA | MODERNA INC | -- | $666,344.00 | 14,600 | BGSXTS3 |
| 0.95% | GH | GUARDANT HEALTH INC | -- | $631,324.50 | 4,850 | BFXC911 |
| 0.86% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $574,766.08 | 3,712 | 2623911 |
| 0.77% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $514,423.00 | 2,275 | B4Q5ZN4 |
| 0.74% | ASND | ASCENDIS PHARMA A/S | -- | $492,981.60 | 2,276 | BWXJHM8 |
| 0.70% | MEDP | MEDPACE HOLDINGS INC | -- | $468,315.09 | 1,051 | BDCBC61 |
| 0.70% | EXEL | EXELIXIS INC | -- | $465,984.00 | 9,600 | 2576941 |
| 0.69% | BBIO | BRIDGEBIO PHARMA INC | -- | $457,827.96 | 7,167 | BK1KWG8 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $445,773.73 | 6,109 | BDJ0LS6 |
| 0.64% | SMMT | SUMMIT THERAPEUTICS INC | -- | $425,947.04 | 28,664 | BMTVQS7 |
| 0.63% | AXSM | AXSOME THERAPEUTICS INC | -- | $419,882.40 | 1,890 | BYZR4X4 |
| 0.58% | SNY | SANOFI-ADR | -- | $387,211.60 | 9,047 | 2964557 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $383,572.42 | 847 | BD59BS7 |
| 0.57% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $379,105.20 | 7,110 | 2437071 |
| 0.56% | BNTX | BIONTECH SE-ADR | -- | $375,546.82 | 4,213 | BK6H543 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $366,705.96 | 5,178 | BYQBFJ8 |
| 0.49% | ONC | BEONE MEDICINES LTD-ADR | -- | $324,408.89 | 1,181 | BYYWPW6 |
| 0.48% | CYTK | CYTOKINETICS INC | -- | $322,853.23 | 4,553 | BBBSBJ5 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $318,758.88 | 6,424 | BSLSJJ0 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $316,666.80 | 1,080 | BD6JX35 |
| 0.43% | HALO | HALOZYME THERAPEUTICS INC | -- | $289,245.92 | 4,364 | 2975098 |
| 0.41% | IBRX | IMMUNITYBIO INC | -- | $274,797.84 | 38,008 | BNSP0B8 |
| 0.40% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $265,564.32 | 1,029 | BQ721R4 |
| 0.38% | ALKS | ALKERMES PLC | -- | $254,655.16 | 6,163 | B3P6D26 |
| 0.38% | PCVX | VAXCYTE INC | -- | $252,268.61 | 5,321 | BKPVGH6 |
| 0.37% | NUVL | NUVALENT INC-A | -- | $247,101.75 | 2,705 | BMVBZD3 |
| 0.35% | IMVT | IMMUNOVANT INC | -- | $232,611.16 | 7,523 | BJRFSB7 |
| 0.33% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $220,116.03 | 2,361 | BDCBCD8 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $215,081.93 | 3,017 | BMPRZV5 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $213,068.10 | 2,526 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $208,920.26 | 3,062 | B17VCN9 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $205,631.27 | 2,231 | BJDX8Y8 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $200,909.80 | 2,905 | BQBBDY8 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $196,625.52 | 6,002 | BLR6XK8 |
| 0.28% | CRSP | CRISPR THERAPEUTICS AG | -- | $184,671.00 | 3,550 | BDHF4K6 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $176,477.70 | 4,423 | BLB0YQ9 |
| 0.26% | CGON | CG ONCOLOGY INC | -- | $173,420.19 | 3,123 | BRBCSP4 |
| 0.26% | CAI | CARIS LIFE SCIENCES INC | -- | $172,320.12 | 10,431 | BT18HP9 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $171,311.36 | 736 | 2501578 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $168,577.64 | 3,773 | BFZQ0L8 |
| 0.25% | ABVX | ABIVAX SA-ADR | -- | $164,647.50 | 2,271 | BLC89B2 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $160,770.20 | 3,074 | BRJ3GY4 |
| 0.24% | APGE | APOGEE THERAPEUTICS INC | -- | $159,623.88 | 2,028 | BM9HHL5 |
| 0.24% | TWST | TWIST BIOSCIENCE CORP | -- | $158,959.90 | 2,266 | BGKG6G7 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $155,875.04 | 4,624 | BTZRLN8 |
| 0.23% | ERAS | ERASCA INC | -- | $154,265.12 | 11,444 | BNLYBF3 |
| 0.22% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $147,733.50 | 3,966 | BKY5JZ8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $147,144.80 | 11,632 | BFNF1D6 |
| 0.22% | TVTX | TRAVERE THERAPEUTICS INC | -- | $146,450.64 | 3,409 | BLFGJD5 |
| 0.21% | VCYT | VERACYTE INC | -- | $140,436.40 | 2,938 | BFTWZY0 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $134,830.92 | 4,252 | BP8JSP4 |
| 0.20% | TXG | 10X GENOMICS INC-CLASS A | -- | $133,619.21 | 4,351 | BKS3RS7 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $131,669.67 | 6,303 | 2713317 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $126,265.92 | 3,872 | BDD19F8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $113,449.05 | 5,863 | BD2B4V0 |
| 0.17% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $113,266.16 | 3,122 | BMX9K07 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $109,092.32 | 3,767 | BK6L288 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $107,107.20 | 2,880 | BQS9486 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $107,027.00 | 4,978 | BP2P6L0 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $104,939.88 | 6,087 | BN15WD1 |
| 0.16% | RLAY | RELAY THERAPEUTICS INC | -- | $103,714.20 | 6,606 | BN2R582 |
| 0.15% | ORKA | ORUKA THERAPEUTICS INC | -- | $98,806.47 | 1,789 | BKVF0J2 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $95,948.00 | 1,411 | BMGJZJ8 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $95,363.73 | 4,587 | BKX9VD3 |
| 0.14% | ALMS | ALUMIS INC | -- | $93,666.96 | 4,674 | BPLQG36 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $93,428.40 | 2,120 | B72ZBG4 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $90,466.02 | 3,246 | BK0VHF6 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $90,305.93 | 1,573 | BMH5RL1 |
| 0.13% | GRAL | GRAIL INC | -- | $86,196.10 | 1,439 | BSLSSX7 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $86,176.88 | 5,692 | BJ5FZ74 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $84,386.25 | 2,925 | BP9N0G0 |
| 0.13% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,239.10 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $82,401.36 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $79,670.16 | 1,698 | BRXB0C0 |
| 0.12% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $78,001.92 | 2,196 | BMFD115 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $77,776.38 | 3,571 | BJ62Z18 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $77,320.14 | 9,271 | 2100362 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $75,626.46 | 4,914 | BFWLC09 |
| 0.11% | KOD | KODIAK SCIENCES INC | -- | $74,899.83 | 2,255 | BFXC933 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $69,662.17 | 19,297 | BM9FJ13 |
| 0.10% | ABCL | ABCELLERA BIOLOGICS INC | -- | $68,711.17 | 11,209 | BL53SR3 |
| 0.10% | PHVS | PHARVARIS NV | -- | $68,595.66 | 2,367 | BMZ2X38 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $66,918.00 | 8,805 | B9NSBM2 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $66,887.19 | 8,049 | BNZB1X8 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $66,688.26 | 2,766 | BPCQZY9 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $66,586.38 | 4,209 | BYSS4X4 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $66,147.40 | 2,140 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $64,593.75 | 1,875 | BSBMN89 |
| 0.10% | ATAI | ATAIBECKLEY INC | -- | $64,593.49 | 13,429 | BWJDYK1 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $64,017.00 | 4,742 | BJH9ZN0 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $62,968.75 | 3,875 | B8DPDT7 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $62,451.20 | 15,232 | BF0DMK7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $62,238.74 | 3,802 | BMVLGP2 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $61,959.50 | 830 | BCDWBX6 |
| 0.09% | QURE | UNIQURE NV | -- | $61,681.80 | 2,305 | BJFSR88 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $61,563.60 | 1,764 | BR3T9B6 |
| 0.09% | NVAX | NOVAVAX INC | -- | $61,494.83 | 6,023 | BJDQXG4 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $60,543.48 | 2,111 | BJQ05Z6 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $60,228.48 | 1,651 | BQKXDX4 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $59,969.79 | 3,261 | BN7Q7R7 |
| 0.09% | INVA | INNOVIVA INC | -- | $58,499.00 | 2,740 | BDDXF67 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $57,628.32 | 10,128 | BNC1BX1 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $57,420.66 | 2,166 | BCBVTX1 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $57,364.97 | 4,369 | BYZM6C2 |
| 0.09% | GHRS | GH RESEARCH PLC | -- | $57,051.78 | 2,294 | BP6C0S2 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $56,739.15 | 2,379 | BBC9WC7 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $56,574.84 | 1,974 | BMVNDH9 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $53,944.11 | 4,059 | BPCK358 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $53,068.80 | 3,455 | BRXYZ57 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $52,438.98 | 1,023 | BDRW1L7 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $50,900.60 | 1,658 | BQXJKH2 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,779.40 | 5,810 | BK4PZ38 |
| 0.08% | PGEN | PRECIGEN INC | -- | $50,488.80 | 13,080 | BKM5C84 |
| 0.08% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,377.80 | 1,870 | BD06CS0 |
| 0.08% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,279.31 | 537 | BNSP8K3 |
| 0.08% | ARDX | ARDELYX INC | -- | $50,044.32 | 9,066 | BN89V40 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $49,991.32 | 2,818 | BP7KZP7 |
| 0.07% | SEPN | SEPTERNA INC | -- | $49,610.58 | 1,657 | BQNKXX2 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $47,916.76 | 1,621 | BLCD809 |
| 0.07% | CMPS | COMPASS PATHWAYS PLC | -- | $46,481.71 | 3,487 | BMC3HS7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $46,016.52 | 2,343 | BQB42F1 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $45,914.20 | 1,730 | BZ7PJQ1 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $45,687.84 | 1,527 | BMGTLY5 |
| 0.07% | HROW | HARROW INC | -- | $45,018.20 | 1,370 | BHNDW86 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $43,187.62 | 1,778 | BSRK699 |
| 0.06% | PSNL | PERSONALIS INC | -- | $43,100.66 | 3,869 | BJQ0608 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $39,602.40 | 6,960 | BYZG9R0 |
| 0.06% | SVRA | SAVARA INC | -- | $39,501.00 | 7,524 | BYXGN81 |
| 0.06% | MNKD | MANNKIND CORP | -- | $39,064.27 | 11,389 | BF081J4 |
| 0.06% | EYPT | EYEPOINT INC | -- | $38,366.86 | 3,062 | BMGS7L1 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $36,804.00 | 6,134 | BLR7H87 |
| 0.05% | ALVO | ALVOTECH SA | -- | $36,630.00 | 12,210 | BPNTJ34 |
| 0.05% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $35,722.56 | 1,172 | BX7RSN3 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $35,701.26 | 3,054 | BYP80F1 |
| 0.05% | ABSI | ABSCI CORP | -- | $35,312.35 | 5,561 | BN94K69 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $34,411.30 | 4,510 | B8K7T65 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $33,968.79 | 1,983 | BQB42H3 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $33,517.90 | 2,185 | BM90J52 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $33,263.75 | 1,495 | B3X26D8 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $32,538.40 | 3,656 | BMCR7V2 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,910.76 | 9,849 | BMFJJ97 |
| 0.05% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $31,663.78 | 2,962 | BMZ4LN0 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $31,018.78 | 2,251 | BMFX8Y7 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $30,940.65 | 1,677 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $30,390.31 | 2,711 | BGCYWN8 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,288.60 | 7,110 | BZ0QMB7 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $29,212.50 | 1,875 | BMNDK09 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $28,865.46 | 3,218 | BYZD465 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $28,277.82 | 3,711 | BKVDFF7 |
| 0.04% | ANNX | ANNEXON INC | -- | $28,135.74 | 5,349 | BMVV9R5 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,100.80 | 2,912 | BJLKVS6 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $28,081.68 | 1,934 | BQS7491 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,748.18 | 8,837 | BBNBTD2 |
| 0.04% | GERN | GERON CORP | -- | $27,614.34 | 23,602 | 2370381 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,489.00 | 2,975 | BFYQFJ2 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $27,180.80 | 992 | BGL0JK3 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $27,080.11 | 3,053 | BDDVW37 |
| 0.04% | OMER | OMEROS CORP | -- | $26,901.72 | 2,622 | B4NB858 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $26,530.16 | 1,604 | BT9K6D8 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $26,130.30 | 5,410 | BMCWKZ2 |
| 0.04% | CRMD | CORMEDIX INC | -- | $23,782.87 | 2,911 | BJ0LT31 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $22,792.94 | 2,707 | BP0TQC5 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,663.04 | 2,083 | BLFBZ32 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $21,763.35 | 1,269 | BD9GVY0 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,681.00 | 1,100 | BKLCWZ3 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $21,669.20 | 763 | BL95N25 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $21,420.33 | 6,673 | BPBJFM7 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $21,407.85 | 2,105 | BMFK3H6 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $20,981.76 | 1,536 | BRJJYT3 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,645.17 | 4,459 | BYV2W40 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,173.44 | 672 | BQD3J33 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $19,797.40 | 6,265 | BYWVTY5 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $19,771.84 | 6,028 | B3MZ6K5 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $19,008.99 | 693 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $18,950.40 | 2,880 | BQHN6C7 |
| 0.03% | ARVN | ARVINAS INC | -- | $18,904.00 | 2,363 | BDZ30Q0 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $18,278.91 | 1,989 | B91XRN2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,728.23 | 4,511 | BYVQJ96 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,637.54 | 11,163 | B4N8MH9 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $17,473.95 | 1,885 | BKLXFX5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,031.40 | 8,308 | BFZNYB7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,684.80 | 2,112 | BSMLR16 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,511.22 | 1,023 | BS2CR64 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,208.10 | 2,349 | BP81R42 |
| 0.02% | KMDA | KAMADA LTD | -- | $16,026.34 | 2,134 | B2Q9833 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $15,663.06 | 3,609 | BKX9NQ0 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $14,943.96 | 548 | B292NQ7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,925.94 | 571 | BS2F741 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,789.49 | 2,397 | BDRJH21 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $14,478.25 | 1,997 | BRCFFK6 |
| 0.02% | OABI | OMNIAB INC | -- | $13,943.64 | 5,322 | BN13S71 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,915.12 | 1,124 | BPRBTY7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,429.90 | 4,631 | BFY7DC4 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $13,400.18 | 2,186 | B12W3P6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $13,246.20 | 4,014 | BMXNGZ6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,115.42 | 1,879 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,089.76 | 3,557 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,974.50 | 7,414 | BFMLGR4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,896.16 | 1,072 | B9L5200 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,336.03 | 2,889 | BLN9Z50 |
| 0.02% | RGNX | REGENXBIO INC | -- | $12,211.96 | 1,873 | BZ0G875 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $12,163.47 | 2,697 | BQ6C357 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,868.75 | 1,125 | BM7V485 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $11,718.43 | 787 | BTNMG41 |
| 0.02% | IVVD | INVIVYD INC | -- | $11,678.16 | 10,244 | BM8NHS1 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,597.57 | 4,013 | BDFKQ07 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,430.72 | 2,646 | 2107437 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,058.32 | 1,736 | BL5B6Z1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,808.00 | 6,176 | BN4JN37 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $10,261.58 | 1,981 | BP7L561 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $10,216.36 | 2,387 | BMVBZF5 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $10,183.02 | 3,611 | BZ8FPH3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,919.04 | 7,136 | BMYTJP4 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $9,541.41 | 3,426 | BYTYP72 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $9,402.24 | 1,416 | BP81RK8 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,004.82 | 3,721 | BZC0D70 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,987.29 | 3,341 | B5LL2C2 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,965.20 | 7,230 | BNR5QT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,398.00 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $8,256.54 | 1,158 | BQV0J03 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,167.99 | 2,089 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,047.80 | 1,052 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,013.28 | 3,454 | BNYJR68 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $7,858.95 | 2,165 | BMF7DT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,822.61 | 2,179 | BY7RB53 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,788.13 | 1,147 | BP2NYN2 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $7,736.96 | 2,464 | BJDX8Z9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,559.15 | 1,387 | 2517058 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,357.30 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $7,098.21 | 4,151 | BKRRKY7 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,329.48 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,924.88 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,588.90 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,938.13 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,684.45 | 2,541 | BMTX3D7 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,191.88 | 804 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,094.58 | 3,608 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,712.71 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 30.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,089,795 | -- | 3,524 | -- |
| 28.87% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,234,668 | -- | 3,374 | -- |
| 25.00% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 16,652,183 | -- | 2,921 | -- |
| 22.58% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,044,543 | -- | 2,639 | -- |
| 21.51% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,326,236 | -- | 2,513 | -- |
| 5.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,608,638 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,003,000.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $17,424,903.41 | 17,424,903 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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