BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,916,671
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/07/2026- NAV
- NAV Change
- Market Price $80.59
- Market Price Change $-0.45
- Trading Volume (M) 19,481
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $79,916,671
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/07/2026- NAV
- NAV Change
- Market Price $80.59
- Market Price Change $-0.45
- Trading Volume (M) 19,481
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/07/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.37% | GILD | GILEAD SCIENCES INC | -- | $4,289,614.00 | 30,905 | 2369174 |
| 5.05% | AMGN | AMGEN INC | -- | $4,032,400.00 | 11,860 | 2023607 |
| 5.01% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,001,182.90 | 9,265 | 2931034 |
| 4.42% | REGN | REGENERON PHARMACEUTICALS | -- | $3,532,974.69 | 4,647 | 2730190 |
| 2.37% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,895,392.64 | 5,932 | B00FWN1 |
| 1.97% | INSM | INSMED INC | -- | $1,571,935.26 | 9,642 | 2614487 |
| 1.44% | BIIB | BIOGEN INC | -- | $1,152,704.04 | 6,564 | 2455965 |
| 1.39% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,108,772.00 | 1,960 | 2430412 |
| 1.22% | ARGX | ARGENX SE - ADR | -- | $971,330.67 | 1,269 | BDVLM39 |
| 1.12% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $898,263.55 | 19,165 | BMVP7Y0 |
| 1.11% | ROIV | ROIVANT SCIENCES LTD | -- | $888,471.75 | 32,017 | BMW4NZ9 |
| 1.11% | MRNA | MODERNA INC | -- | $885,293.37 | 17,667 | BGSXTS3 |
| 1.08% | ILMN | ILLUMINA INC | -- | $864,976.04 | 6,841 | 2613990 |
| 1.07% | RVMD | REVOLUTION MEDICINES INC | -- | $853,610.85 | 8,865 | BL71K91 |
| 1.04% | INCY | INCYTE CORP | -- | $834,028.38 | 8,902 | 2471950 |
| 0.85% | VTRS | VIATRIS INC | -- | $677,832.12 | 51,507 | BMWS3X9 |
| 0.83% | SMMT | SUMMIT THERAPEUTICS INC | -- | $666,664.92 | 34,686 | BMTVQS7 |
| 0.81% | MEDP | MEDPACE HOLDINGS INC | -- | $645,311.88 | 1,269 | BDCBC61 |
| 0.78% | BBIO | BRIDGEBIO PHARMA INC | -- | $623,848.89 | 8,673 | BK1KWG8 |
| 0.76% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $607,201.92 | 2,754 | BV9G6B8 |
| 0.74% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $587,741.00 | 4,490 | 2623911 |
| 0.68% | GH | GUARDANT HEALTH INC | -- | $547,391.10 | 5,867 | BFXC911 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $546,047.10 | 7,390 | BDJ0LS6 |
| 0.66% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $525,848.76 | 2,754 | B4Q5ZN4 |
| 0.66% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $525,711.03 | 1,027 | BD59BS7 |
| 0.64% | SNY | SANOFI-ADR | -- | $512,741.67 | 10,949 | 2964557 |
| 0.64% | EXEL | EXELIXIS INC | -- | $511,031.83 | 11,617 | 2576941 |
| 0.61% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $483,716.88 | 8,604 | 2437071 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $456,703.52 | 5,096 | BK6H543 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $434,462.60 | 1,430 | BYYWPW6 |
| 0.49% | PCVX | VAXCYTE INC | -- | $390,722.22 | 6,438 | BKPVGH6 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $386,245.86 | 2,289 | BYZR4X4 |
| 0.48% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $383,292.70 | 6,265 | BYQBFJ8 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $381,829.05 | 1,245 | BQ721R4 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $363,799.37 | 7,771 | BSLSJJ0 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $360,729.32 | 5,509 | BBBSBJ5 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $345,562.91 | 1,309 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $335,808.00 | 5,280 | 2975098 |
| 0.42% | NUVL | NUVALENT INC-A | -- | $334,766.50 | 3,274 | BMVBZD3 |
| 0.40% | ABVX | ABIVAX SA-ADR | -- | $320,087.04 | 2,748 | BLC89B2 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $315,498.26 | 45,991 | BNSP0B8 |
| 0.39% | KYMR | KYMERA THERAPEUTICS INC | -- | $310,700.10 | 3,651 | BMPRZV5 |
| 0.37% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $296,206.25 | 2,855 | BDCBCD8 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $264,746.30 | 3,055 | BF2YWG4 |
| 0.33% | CGON | CG ONCOLOGY INC | -- | $263,742.18 | 3,778 | BRBCSP4 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $258,636.82 | 7,261 | BLR6XK8 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $258,159.35 | 2,699 | BJDX8Y8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $257,654.74 | 3,703 | B17VCN9 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $250,313.34 | 4,757 | BMDJ0C9 |
| 0.31% | ALKS | ALKERMES PLC | -- | $246,164.10 | 7,455 | B3P6D26 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $236,662.50 | 12,622 | BT18HP9 |
| 0.30% | ERAS | ERASCA INC | -- | $236,281.00 | 13,850 | BNLYBF3 |
| 0.29% | APLS | APELLIS PHARMACEUTICALS INC | -- | $232,722.60 | 5,718 | BYTQ6X1 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $227,743.60 | 4,564 | BFZQ0L8 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $224,098.66 | 9,106 | BJRFSB7 |
| 0.27% | XENE | XENON PHARMACEUTICALS INC | -- | $214,573.30 | 3,722 | BRJ3GY4 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $213,362.10 | 4,293 | BDHF4K6 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $211,632.05 | 5,351 | BLB0YQ9 |
| 0.26% | APGE | APOGEE THERAPEUTICS INC | -- | $204,202.56 | 2,452 | BM9HHL5 |
| 0.24% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $190,559.80 | 3,485 | BQS9486 |
| 0.23% | LGND | LIGAND PHARMACEUTICALS | -- | $182,744.10 | 891 | 2501578 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $179,912.44 | 4,684 | BDD19F8 |
| 0.23% | SYRE | SPYRE THERAPEUTICS INC | -- | $179,865.60 | 3,513 | BQBBDY8 |
| 0.22% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $174,365.22 | 5,142 | BP8JSP4 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $173,416.32 | 14,076 | BFNF1D6 |
| 0.21% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $170,449.18 | 5,594 | BTZRLN8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $168,458.34 | 7,626 | 2713317 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $155,935.00 | 4,798 | BKY5JZ8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $137,713.95 | 7,095 | BD2B4V0 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $137,429.04 | 2,742 | BGKG6G7 |
| 0.17% | DYN | DYNE THERAPEUTICS INC | -- | $133,748.40 | 7,365 | BN15WD1 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $131,199.00 | 2,165 | BKVF0J2 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $130,850.28 | 1,903 | BMH5RL1 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $130,712.40 | 2,565 | B72ZBG4 |
| 0.16% | TVTX | TRAVERE THERAPEUTICS INC | -- | $130,702.09 | 4,127 | BLFGJD5 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $129,008.88 | 5,544 | BKX9VD3 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $127,680.00 | 3,192 | BL55460 |
| 0.16% | ALMS | ALUMIS INC | -- | $126,163.05 | 5,655 | BPLQG36 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $121,445.39 | 3,929 | BK0VHF6 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $119,295.00 | 6,025 | BP2P6L0 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $114,860.48 | 5,264 | BKS3RS7 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $114,632.96 | 2,656 | BMFD115 |
| 0.14% | VCYT | VERACYTE INC | -- | $114,293.25 | 3,555 | BFTWZY0 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $114,112.95 | 1,707 | BMGJZJ8 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $114,086.70 | 2,730 | BFXC933 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $111,600.93 | 4,557 | BK6L288 |
| 0.14% | SRPT | SAREPTA THERAPEUTICS INC | -- | $108,199.04 | 4,688 | B8DPDT7 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $107,772.60 | 7,995 | BN2R582 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $107,599.80 | 11,220 | 2100362 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $100,473.82 | 2,053 | BRXB0C0 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $100,217.40 | 3,540 | BP9N0G0 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $100,077.45 | 4,323 | BJ62Z18 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $99,166.66 | 4,621 | BLB0YH0 |
| 0.12% | ADMA | ADMA BIOLOGICS INC | -- | $98,656.04 | 10,654 | B9NSBM2 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $97,204.80 | 3,945 | BN7Q7R7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $94,434.48 | 6,888 | BJ5FZ74 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $93,918.92 | 5,948 | BFWLC09 |
| 0.12% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $92,023.31 | 2,621 | BCBVTX1 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $91,786.80 | 4,460 | BV2DHY6 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $90,061.51 | 2,387 | BMVNDH9 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $87,048.00 | 3,348 | BPCQZY9 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $86,307.90 | 2,555 | BJQ05Z6 |
| 0.11% | GRAL | GRAIL INC | -- | $85,668.45 | 1,743 | BSLSSX7 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,223.26 | 9,739 | BNZB1X8 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $79,934.51 | 4,913 | BPCK358 |
| 0.10% | PHVS | PHARVARIS NV | -- | $79,789.44 | 2,866 | BMZ2X38 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $79,708.41 | 1,003 | BCDWBX6 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $79,604.35 | 2,879 | BBC9WC7 |
| 0.10% | INVA | INNOVIVA INC | -- | $77,126.64 | 3,313 | BDDXF67 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $77,041.20 | 1,240 | BDRW1L7 |
| 0.09% | VCEL | VERICEL CORP | -- | $75,692.43 | 2,271 | BSBMN89 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $75,210.00 | 4,600 | BMVLGP2 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $75,141.60 | 5,736 | BJH9ZN0 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $74,483.31 | 23,349 | BM9FJ13 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $73,409.72 | 1,997 | BQKXDX4 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $71,598.20 | 5,284 | BYZM6C2 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $71,480.56 | 2,588 | BKSGZN7 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,400.68 | 2,132 | BR3T9B6 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $67,930.24 | 3,776 | BMX9K07 |
| 0.08% | ARDX | ARDELYX INC | -- | $65,271.50 | 10,970 | BN89V40 |
| 0.08% | PGEN | PRECIGEN INC | -- | $65,211.36 | 15,828 | BKM5C84 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,474.27 | 7,031 | BK4PZ38 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $62,673.56 | 1,961 | BLCD809 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $61,579.92 | 16,248 | BWJDYK1 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $61,180.96 | 18,428 | BF0DMK7 |
| 0.08% | MAZE | MAZE THERAPEUTICS INC | -- | $60,994.49 | 2,153 | BSRK699 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $60,651.71 | 2,009 | BQXJKH2 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $60,335.86 | 2,834 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $59,789.10 | 8,421 | BYZG9R0 |
| 0.07% | HROW | HARROW INC | -- | $58,742.94 | 1,658 | BHNDW86 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,396.32 | 3,411 | BP7KZP7 |
| 0.07% | NVAX | NOVAVAX INC | -- | $58,158.24 | 7,288 | BJDQXG4 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,996.21 | 12,253 | BNC1BX1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $54,738.80 | 2,435 | BQB42H3 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $54,671.25 | 3,585 | BMZ4LN0 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,008.90 | 3,694 | BYP80F1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $52,681.50 | 5,090 | BYSS4X4 |
| 0.07% | SVRA | SAVARA INC | -- | $52,615.34 | 9,103 | BYXGN81 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $51,374.18 | 923 | BL95N25 |
| 0.06% | EYPT | EYEPOINT INC | -- | $50,263.28 | 3,704 | BMGS7L1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $50,090.64 | 14,776 | BPNTJ34 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,754.52 | 2,003 | BQNKXX2 |
| 0.06% | GERN | GERON CORP | -- | $49,687.44 | 28,556 | 2370381 |
| 0.06% | QURE | UNIQURE NV | -- | $47,769.18 | 2,787 | BJFSR88 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $46,551.96 | 1,421 | BX7RSN3 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,525.93 | 1,847 | BMGTLY5 |
| 0.06% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $45,491.32 | 2,261 | BD06CS0 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $44,754.60 | 13,562 | BL53SR3 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $44,201.70 | 5,457 | B8K7T65 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,567.14 | 7,422 | BLR7H87 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,756.82 | 2,029 | BNFWZS4 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,779.30 | 1,810 | B3X26D8 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $40,737.00 | 2,775 | BP6C0S2 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,702.20 | 3,524 | BJLKVS6 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $40,639.46 | 2,722 | BMFX8Y7 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $40,589.85 | 651 | BNSP8K3 |
| 0.05% | XNCR | XENCOR INC | -- | $40,389.11 | 3,281 | BGCYWN8 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,826.30 | 4,490 | BKVDFF7 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $39,780.33 | 4,183 | BRXYZ57 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $39,274.98 | 2,643 | BM90J52 |
| 0.05% | ANNX | ANNEXON INC | -- | $38,785.25 | 6,475 | BMVV9R5 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $38,373.84 | 8,604 | BZ0QMB7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $37,736.79 | 2,093 | BZ7PJQ1 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $37,541.52 | 2,267 | BMNDK09 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $37,535.40 | 11,916 | BMFJJ97 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,047.45 | 4,423 | BMCR7V2 |
| 0.04% | MNKD | MANNKIND CORP | -- | $35,422.31 | 13,783 | BF081J4 |
| 0.04% | OMER | OMEROS CORP | -- | $34,817.58 | 3,171 | B4NB858 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,327.44 | 3,892 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $34,236.00 | 3,600 | BFYQFJ2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $34,233.84 | 1,944 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,023.90 | 1,330 | BKLCWZ3 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,589.70 | 7,579 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $32,540.94 | 2,862 | BDZ30Q0 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,193.00 | 1,533 | BD9GVY0 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $32,050.27 | 2,342 | BQS7491 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $31,307.30 | 1,858 | BRJJYT3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $31,136.56 | 2,548 | BMFK3H6 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $30,046.94 | 1,199 | BGL0JK3 |
| 0.04% | PSNL | PERSONALIS INC | -- | $28,881.77 | 4,681 | BJQ0608 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $28,813.20 | 3,694 | BDDVW37 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $27,535.75 | 8,075 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $26,981.64 | 3,486 | BQHN6C7 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $26,338.86 | 10,053 | BFZNYB7 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,267.08 | 3,524 | BJ0LT31 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,195.72 | 7,282 | B3MZ6K5 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,946.88 | 2,408 | B91XRN2 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $24,703.14 | 10,694 | BBNBTD2 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $24,479.28 | 4,857 | BMXNGZ6 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $24,393.60 | 840 | BPBPCG8 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,364.56 | 2,517 | BLFBZ32 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,847.48 | 2,556 | BSMLR16 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $23,725.05 | 1,713 | BP81RK8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,454.60 | 2,418 | BRCFFK6 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $23,378.80 | 4,220 | BMC3HS7 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $23,367.68 | 2,282 | BKLXFX5 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,357.49 | 813 | BQD3J33 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $23,325.57 | 2,979 | BJDX8Z9 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,541.54 | 5,458 | BYVQJ96 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,293.25 | 2,581 | B2Q9833 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $20,865.15 | 3,495 | BLN9Z50 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $20,712.78 | 951 | BTNMG41 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $20,602.15 | 3,265 | BQ6C357 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,231.25 | 5,395 | BYV2W40 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,923.20 | 2,264 | BZ0G875 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $19,772.30 | 2,654 | B12W3P6 |
| 0.02% | ABSI | ABSCI CORP | -- | $19,639.92 | 6,726 | BN94K69 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,452.96 | 13,509 | B4N8MH9 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,209.52 | 664 | B292NQ7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,934.76 | 5,602 | BFY7DC4 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $18,926.61 | 6,549 | BMCWKZ2 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $18,835.83 | 2,841 | BP81R42 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,445.57 | 1,299 | B9L5200 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,338.26 | 1,362 | BPRBTY7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $16,905.84 | 4,858 | BDFKQ07 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $16,683.12 | 1,363 | BM7V485 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,186.50 | 3,270 | BP0TQC5 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,990.84 | 12,396 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,921.75 | 7,475 | BN4JN37 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,863.72 | 2,276 | B7F2TY6 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,010.10 | 2,870 | BMVBZF5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,514.12 | 3,204 | 2107437 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,469.72 | 692 | BS2F741 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,998.11 | 4,501 | BZC0D70 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,584.29 | 1,399 | BQV0J03 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,219.42 | 4,306 | BK5MWR1 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,021.40 | 2,620 | BMF7DT9 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,769.68 | 4,146 | BYTYP72 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,452.08 | 5,021 | BKRRKY7 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,203.28 | 8,973 | BFMLGR4 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $11,962.84 | 4,366 | BZ8FPH3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,957.36 | 4,364 | BKX9NQ0 |
| 0.01% | EOLS | EVOLUS INC | -- | $11,827.92 | 2,899 | BDRJH21 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,760.00 | 2,100 | BL5B6Z1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,167.29 | 6,687 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,816.21 | 1,271 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,756.50 | 2,525 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,442.52 | 2,637 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,157.70 | 2,073 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $9,722.89 | 6,439 | BN13S71 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,399.60 | 3,320 | BPTK6Z2 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,001.18 | 4,041 | B5LL2C2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,776.66 | 4,181 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,040.88 | 1,386 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,942.60 | 2,394 | BP7L561 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,884.25 | 1,675 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,473.05 | 9,696 | BNNXX52 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,245.05 | 2,549 | BKTV702 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,219.06 | 8,742 | BNR5QT9 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,239.37 | 8,633 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,136.92 | 3,076 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,067.56 | 2,786 | BLBR8D5 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,930.92 | 973 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,567.19 | 4,363 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,413.71 | 10,354 | BJ0CK86 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $25.71 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.43% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 27,518,609 | -- | 4,733 | -- |
| 31.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,902,219 | -- | 4,283 | -- |
| 26.93% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,524,168 | -- | 3,702 | -- |
| 19.20% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,343,674 | -- | 2,639 | -- |
| 14.48% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,570,258 | -- | 1,990 | -- |
| 4.61% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,680,389 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $24,815,004.99 | 24,815,005 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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