BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 8/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 9.47% | 28.93% | 1.11% | 9.77% | -16.62% | 3.73% | -4.43% | -2.92% | 14.03% | 04/07/2010 |
| BIB NAV | 9.35% | 28.93% | 1.18% | 9.85% | -16.62% | 3.78% | -4.40% | -2.92% | 14.03% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/15/2025- NAV $56.55
- NAV Change $-0.60
- Market Price $56.56
- Market Price Change $-0.64
- Trading Volume (M) 4,215
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/15/2025- NAV $56.55
- NAV Change $-0.60
- Market Price $56.56
- Market Price Change $-0.64
- Trading Volume (M) 4,215
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/15/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.53% | GILD | GILEAD SCIENCES INC | -- | $2,486,121.14 | 22,091 | 2369174 |
| 4.22% | AMGN | AMGEN INC | -- | $2,315,387.20 | 8,438 | 2023607 |
| 3.94% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,162,655.00 | 5,500 | 2931034 |
| 3.86% | REGN | REGENERON PHARMACEUTICALS | -- | $2,116,292.64 | 3,696 | 2730190 |
| 3.36% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,841,793.16 | 3,994 | B00FWN1 |
| 2.95% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,620,161.90 | 20,758 | 2989044 |
| 1.67% | INSM | INSMED INC | -- | $916,525.42 | 6,403 | 2614487 |
| 1.53% | ARGX | ARGENX SE - ADR | -- | $838,567.64 | 1,108 | BDVLM39 |
| 1.35% | BIIB | BIOGEN INC | -- | $738,098.00 | 5,150 | 2455965 |
| 1.16% | UTHR | UNITED THERAPEUTICS CORP | -- | $638,526.24 | 1,584 | 2430412 |
| 1.03% | INCY | INCYTE CORP | -- | $565,518.28 | 6,802 | 2471950 |
| 1.02% | ILMN | ILLUMINA INC | -- | $561,417.96 | 5,563 | 2613990 |
| 0.95% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $520,536.35 | 14,809 | BMVP7Y0 |
| 0.92% | TEM | TEMPUS AI INC | -- | $502,948.04 | 5,908 | BSLSJJ0 |
| 0.91% | MEDP | MEDPACE HOLDINGS INC | -- | $501,870.51 | 1,011 | BDCBC61 |
| 0.90% | SMMT | SUMMIT THERAPEUTICS INC | -- | $494,371.88 | 26,102 | BMTVQS7 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $488,590.76 | 3,479 | 2623911 |
| 0.88% | ONC | BEONE MEDICINES LTD-ADR | -- | $482,788.31 | 1,453 | BYYWPW6 |
| 0.84% | SNY | SANOFI-ADR | -- | $461,118.42 | 9,891 | 2964557 |
| 0.76% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $415,319.08 | 2,134 | BV9G6B8 |
| 0.72% | VTRS | VIATRIS INC | -- | $396,019.20 | 41,252 | BMWS3X9 |
| 0.68% | EXEL | EXELIXIS INC | -- | $373,871.84 | 9,584 | 2576941 |
| 0.65% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $358,110.46 | 6,739 | 2437071 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $343,558.80 | 3,510 | BK6H543 |
| 0.63% | BBIO | BRIDGEBIO PHARMA INC | -- | $343,407.84 | 6,672 | BK1KWG8 |
| 0.62% | IONS | IONIS PHARMACEUTICALS INC | -- | $341,854.50 | 5,595 | BDJ0LS6 |
| 0.61% | ROIV | ROIVANT SCIENCES LTD | -- | $333,321.30 | 23,894 | BMW4NZ9 |
| 0.60% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $331,542.40 | 779 | BD59BS7 |
| 0.60% | HALO | HALOZYME THERAPEUTICS INC | -- | $330,508.90 | 4,330 | 2975098 |
| 0.59% | MRNA | MODERNA INC | -- | $324,600.84 | 13,593 | BGSXTS3 |
| 0.55% | RVMD | REVOLUTION MEDICINES INC | -- | $302,379.00 | 6,545 | BL71K91 |
| 0.54% | VRNA | VERONA PHARMA PLC - ADR | -- | $293,900.31 | 2,763 | BYWPZK5 |
| 0.49% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $271,351.74 | 2,167 | B4Q5ZN4 |
| 0.43% | GH | GUARDANT HEALTH INC | -- | $238,610.45 | 4,355 | BFXC911 |
| 0.39% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $214,723.08 | 2,236 | BF2YWG4 |
| 0.38% | CYTK | CYTOKINETICS INC | -- | $207,450.24 | 4,196 | BBBSBJ5 |
| 0.37% | AXSM | AXSOME THERAPEUTICS INC | -- | $202,020.75 | 1,730 | BYZR4X4 |
| 0.34% | NUVL | NUVALENT INC-A | -- | $185,011.47 | 2,331 | BMVBZD3 |
| 0.32% | CRSP | CRISPR THERAPEUTICS AG | -- | $175,544.40 | 3,035 | BDHF4K6 |
| 0.31% | RNA | AVIDITY BIOSCIENCES INC | -- | $170,452.36 | 4,238 | BMWHPY1 |
| 0.30% | MRUS | MERUS NV | -- | $165,731.06 | 2,434 | BZBY005 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $164,259.30 | 2,785 | B17VCN9 |
| 0.29% | KRYS | KRYSTAL BIOTECH INC | -- | $158,357.07 | 1,017 | BD6JX35 |
| 0.28% | ALKS | ALKERMES PLC | -- | $153,869.04 | 5,802 | B3P6D26 |
| 0.27% | ACLX | ARCELLX INC | -- | $145,737.60 | 1,938 | BPCJ1Q2 |
| 0.26% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $145,108.94 | 5,882 | 2713317 |
| 0.26% | PCVX | VAXCYTE INC | -- | $140,585.00 | 4,535 | BKPVGH6 |
| 0.25% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $139,192.85 | 4,855 | BYQBFJ8 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $129,164.79 | 1,741 | BJDX8Y8 |
| 0.23% | ADMA | ADMA BIOLOGICS INC | -- | $128,397.60 | 8,392 | B9NSBM2 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $127,210.02 | 2,179 | BDCBCD8 |
| 0.22% | AKRO | AKERO THERAPEUTICS INC | -- | $120,108.55 | 2,803 | BK7Y2V9 |
| 0.20% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $112,323.12 | 3,336 | BFZQ0L8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $112,219.17 | 678 | 2501578 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $111,204.61 | 3,293 | BDD19F8 |
| 0.20% | KYMR | KYMERA THERAPEUTICS INC | -- | $108,176.64 | 2,288 | BMPRZV5 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $107,827.06 | 11,014 | BFNF1D6 |
| 0.20% | APLS | APELLIS PHARMACEUTICALS INC | -- | $107,755.02 | 4,418 | BYTQ6X1 |
| 0.19% | INDV | INDIVIOR PLC | -- | $101,686.88 | 4,384 | BP0BQQ5 |
| 0.18% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $97,303.36 | 2,872 | BMX9K07 |
| 0.18% | XENE | XENON PHARMACEUTICALS INC | -- | $97,137.01 | 2,699 | BRJ3GY4 |
| 0.18% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $96,309.00 | 3,321 | BJ62Z18 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $95,129.28 | 3,944 | BP8JSP4 |
| 0.17% | IMVT | IMMUNOVANT INC | -- | $93,288.71 | 6,007 | BJRFSB7 |
| 0.17% | CGON | CG ONCOLOGY INC | -- | $92,728.00 | 2,680 | BRBCSP4 |
| 0.16% | VCYT | VERACYTE INC | -- | $87,769.98 | 2,754 | BFTWZY0 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $86,528.33 | 1,967 | B72ZBG4 |
| 0.15% | IBRX | IMMUNITYBIO INC | -- | $85,000.28 | 31,022 | BNSP0B8 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $83,677.25 | 10,825 | B19FQ48 |
| 0.15% | MLYS | MINERALYS THERAPEUTICS INC | -- | $82,920.90 | 2,290 | BP9N0G0 |
| 0.14% | ALVO | ALVOTECH SA | -- | $76,157.48 | 9,379 | BPNTJ34 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $75,478.81 | 3,077 | BK0VHF6 |
| 0.14% | ANIP | ANI PHARMACEUTICALS INC | -- | $75,293.22 | 762 | BCDWBX6 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $75,246.08 | 3,536 | BK6L288 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $73,921.14 | 3,357 | BLB0YQ9 |
| 0.13% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $73,870.50 | 2,035 | BCBVTX1 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $73,194.84 | 1,476 | BMH5RL1 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $72,838.40 | 1,216 | BMGJZJ8 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $71,860.23 | 3,123 | BLFGJD5 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $70,902.84 | 4,188 | BKX9VD3 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $70,224.00 | 5,600 | BNZB1X8 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $69,847.20 | 5,340 | BJ5FZ74 |
| 0.12% | DNLI | DENALI THERAPEUTICS INC | -- | $67,260.76 | 5,111 | BD2B4V0 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $67,013.73 | 14,049 | BM9FJ13 |
| 0.12% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $65,520.00 | 2,016 | BKSGZN7 |
| 0.12% | ZLAB | ZAI LAB LTD-ADR | -- | $64,925.28 | 2,034 | BD9GVY0 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $60,809.07 | 4,747 | BFWLC09 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $60,323.91 | 3,453 | B8DPDT7 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $59,565.76 | 1,616 | BM9HHL5 |
| 0.10% | MNKD | MANNKIND CORP | -- | $57,474.54 | 10,683 | BF081J4 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $56,618.10 | 7,353 | 2100362 |
| 0.10% | VCEL | VERICEL CORP | -- | $55,550.56 | 1,768 | BSBMN89 |
| 0.10% | HROW | HARROW INC | -- | $55,194.98 | 1,289 | BHNDW86 |
| 0.10% | ARDX | ARDELYX INC | -- | $54,897.71 | 8,407 | BN89V40 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $54,401.28 | 1,488 | BRXB0C0 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $54,346.08 | 2,242 | BL55460 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $54,166.32 | 2,106 | BGKG6G7 |
| 0.10% | TXG | 10X GENOMICS INC-CLASS A | -- | $52,118.40 | 3,904 | BKS3RS7 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $51,630.81 | 3,399 | BDGMC59 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $51,401.42 | 3,997 | BN15WD1 |
| 0.09% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $50,607.80 | 3,694 | BKY5JZ8 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $49,849.68 | 3,919 | BYSS4X4 |
| 0.09% | GRAL | GRAIL INC | -- | $49,791.78 | 1,266 | BSLSSX7 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $49,689.64 | 4,004 | BLR6XK8 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $48,957.68 | 2,078 | BMFX8Y7 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $48,015.90 | 1,395 | BLCD809 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $47,884.32 | 3,023 | BN7Q7R7 |
| 0.08% | NVAX | NOVAVAX INC | -- | $45,991.36 | 5,692 | BJDQXG4 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $45,635.85 | 10,491 | BL53SR3 |
| 0.08% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $45,159.12 | 1,656 | BNFWZS4 |
| 0.08% | STOK | STOKE THERAPEUTICS INC | -- | $44,904.60 | 1,919 | BJQ05Z6 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,728.08 | 1,628 | B3X26D8 |
| 0.08% | INVA | INNOVIVA INC | -- | $43,107.75 | 2,205 | BDDXF67 |
| 0.08% | TRML | TOURMALINE BIO INC | -- | $42,932.65 | 901 | BQ80NC6 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,408.32 | 7,912 | BN4RD42 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $42,278.60 | 2,093 | BQS9486 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $42,091.66 | 3,638 | BYZM6C2 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,422.08 | 5,628 | BLR7H87 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $41,293.44 | 4,288 | B8K7T65 |
| 0.08% | GMAB | GENMAB A/S -SP ADR | -- | $41,229.27 | 1,473 | BBC9WC7 |
| 0.08% | ETNB | 89BIO INC | -- | $41,142.60 | 5,130 | BK1K484 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $39,569.89 | 989 | BQV0J03 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $39,508.56 | 4,221 | BRJZSK0 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $39,494.52 | 1,131 | BX7RSN3 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $39,044.43 | 2,451 | BPCQZY9 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $37,770.43 | 5,419 | BYZG9R0 |
| 0.07% | PGEN | PRECIGEN INC | -- | $37,249.84 | 10,376 | BKM5C84 |
| 0.07% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $37,149.75 | 3,135 | BPCK358 |
| 0.06% | SPRY | ARS PHARMACEUTICALS INC | -- | $34,371.96 | 3,451 | BMCR7V2 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $32,456.40 | 3,182 | BRXYZ57 |
| 0.06% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $32,438.79 | 2,419 | BMGS7L1 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $31,894.00 | 1,724 | BMFD115 |
| 0.06% | RAPP | RAPPORT THERAPEUTICS INC | -- | $31,703.86 | 1,282 | BR3T9B6 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $31,490.48 | 2,122 | BQBBDY8 |
| 0.06% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,505.02 | 6,734 | BZ0QMB7 |
| 0.06% | CRMD | CORMEDIX INC | -- | $30,182.90 | 2,386 | BJ0LT31 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $29,275.26 | 1,621 | BZ7PJQ1 |
| 0.05% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $28,881.30 | 714 | BQ721R4 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $28,832.38 | 3,575 | BJH9ZN0 |
| 0.05% | QURE | UNIQURE NV | -- | $28,542.54 | 1,924 | BJFSR88 |
| 0.05% | GERN | GERON CORP | -- | $28,430.22 | 22,386 | 2370381 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $28,224.42 | 714 | BL95N25 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $28,148.96 | 2,452 | BJLKVS6 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $27,708.50 | 9,175 | BNC1BX1 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $27,273.17 | 3,002 | BYTYP72 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,775.00 | 2,500 | BKVDFF7 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $26,645.26 | 11,738 | BF0DMK7 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $25,991.02 | 3,811 | BP2P6L0 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $25,604.21 | 7,927 | BMFJJ97 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $25,589.52 | 3,564 | BLB0YH0 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $25,355.25 | 2,655 | BPQYY97 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $25,329.60 | 1,759 | BMNDK09 |
| 0.05% | KURA | KURA ONCOLOGY INC | -- | $24,983.03 | 3,043 | BYZD465 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $24,674.16 | 1,596 | BQS7491 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $24,465.56 | 6,026 | BN2R582 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $23,807.76 | 1,748 | BD06CS0 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $23,461.70 | 629 | BQD3J33 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $23,279.40 | 4,860 | BK4PZ38 |
| 0.04% | NRIX | NURIX THERAPEUTICS INC | -- | $23,235.60 | 2,680 | BMVLGP2 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $23,019.70 | 1,870 | BMVNDH9 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $22,815.80 | 1,204 | BMGTLY5 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,617.00 | 2,513 | 2107437 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,205.40 | 1,428 | BM7V485 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,965.92 | 1,016 | BKLCWZ3 |
| 0.04% | SVRA | SAVARA INC | -- | $21,927.14 | 6,074 | BYXGN81 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $21,903.36 | 3,072 | BMDJ0C9 |
| 0.04% | XNCR | XENCOR INC | -- | $21,250.47 | 2,503 | BGCYWN8 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $20,784.96 | 1,031 | BDRW1L7 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $20,692.59 | 2,823 | BFYQFJ2 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $20,097.42 | 1,317 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $19,868.58 | 2,567 | BDZ30Q0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $19,368.26 | 6,967 | BBNBTD2 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $19,232.00 | 2,404 | BMZ4LN0 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $19,083.52 | 1,088 | BYXV9H7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $18,510.16 | 4,616 | BPBJFM7 |
| 0.03% | PSNL | PERSONALIS INC | -- | $18,412.65 | 3,105 | BJQ0608 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,948.88 | 3,492 | BYVQJ96 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $17,314.15 | 955 | BKC9SX3 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,641.36 | 522 | B292NQ7 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $16,406.88 | 3,192 | BMC3HS7 |
| 0.03% | RGNX | REGENXBIO INC | -- | $16,043.85 | 1,765 | BZ0G875 |
| 0.03% | ERAS | ERASCA INC | -- | $15,934.40 | 9,959 | BNLYBF3 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,928.92 | 2,709 | BYP80F1 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,455.04 | 1,894 | B91XRN2 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $15,354.36 | 2,708 | BDDVW37 |
| 0.03% | EOLS | EVOLUS INC | -- | $15,010.32 | 2,264 | BDRJH21 |
| 0.03% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $14,975.73 | 2,161 | BP7KZP7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $14,954.76 | 2,724 | BQHN6C7 |
| 0.03% | ALMS | ALUMIS INC | -- | $14,716.80 | 3,360 | BPLQG36 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,614.71 | 1,983 | BMYRFN8 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $14,295.68 | 12,764 | BWFZX59 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $13,896.06 | 1,922 | BLFBZ32 |
| 0.03% | INBX | INHIBRX BIOSCIENCES INC | -- | $13,864.35 | 510 | BNSP8K3 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $13,760.48 | 5,059 | BMCWKZ2 |
| 0.02% | CGEM | CULLINAN THERAPEUTICS INC | -- | $13,201.65 | 2,079 | BM90J52 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $13,014.60 | 2,180 | BP81R42 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $12,656.40 | 10,547 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,194.14 | 3,787 | BDFKQ07 |
| 0.02% | ABSI | ABSCI CORP | -- | $11,748.08 | 4,484 | BN94K69 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,696.56 | 1,996 | BMFK3H6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $11,077.20 | 1,629 | BKLXFX5 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $10,866.45 | 655 | BPBPCG8 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,639.86 | 1,551 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,525.65 | 705 | BN72KB0 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,406.55 | 1,855 | BYX2Z16 |
| 0.02% | ALEC | ALECTOR INC | -- | $10,398.48 | 3,513 | BJ4LDC4 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,235.09 | 2,851 | BFY7DC4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,765.43 | 1,957 | BMF7DT9 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,603.93 | 3,857 | BMVV9R5 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $9,300.72 | 7,046 | BFMLGR4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $9,150.40 | 3,010 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,079.74 | 2,073 | B12W3P6 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,918.69 | 911 | BQB9HM8 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $8,917.92 | 2,252 | BMXNGZ6 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $8,914.29 | 2,497 | BKX9NQ0 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,841.20 | 7,688 | BFZNYB7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $8,759.90 | 502 | BS2F741 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $8,751.92 | 3,529 | BZC0D70 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $8,639.68 | 5,684 | BN4JN37 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $8,511.87 | 1,879 | BP7L561 |
| 0.02% | OMER | OMEROS CORP | -- | $8,425.40 | 2,060 | B4NB858 |
| 0.02% | HUMA | HUMACYTE INC | -- | $8,341.56 | 5,452 | BMYTJP4 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,192.66 | 1,946 | BY7RB53 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $7,860.48 | 2,944 | BZ8FPH3 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $7,813.96 | 1,652 | BL5B6Z1 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $7,278.08 | 5,686 | B3MZ6K5 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,105.28 | 2,912 | B5LL2C2 |
| 0.01% | OABI | OMNIAB INC | -- | $6,924.61 | 4,301 | BN13S71 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $6,827.60 | 520 | BTNMG41 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $6,750.04 | 1,334 | BP81RK8 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $6,273.08 | 1,166 | BQ6C357 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,947.11 | 1,521 | BSMLR16 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,609.92 | 752 | B9L5200 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,443.33 | 6,464 | BPG5P75 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,420.10 | 3,738 | BKMQF66 |
| 0.01% | NKTX | NKARTA INC | -- | $4,915.15 | 2,495 | BK80YJ8 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,847.04 | 2,376 | BMW5LX6 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,138.20 | 2,178 | BLBR8D5 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $3,850.92 | 4,029 | BCZS820 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,456.96 | 2,216 | BFDV8K0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,300.21 | 2,157 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,104.53 | 1,837 | BNLYBJ7 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,636.18 | 2,968 | BF12XC2 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,591.12 | 1,322 | BNKF6N0 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,070.43 | 4,977 | BJL38Z1 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,011.60 | 856 | BMF1LJ7 |
| -- | PEPG | PEPGEN INC | -- | $1,825.32 | 1,148 | BMTX3D7 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,662.51 | 1,101 | BP2TPK4 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,254.75 | 175 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,080.28 | 452 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $774.68 | 428 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 31.75% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,417,369 | -- | 3,675 | -- |
| 25.98% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 14,251,436 | -- | 3,007 | -- |
| 24.64% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,516,826 | -- | 2,852 | -- |
| 20.70% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 11,355,650 | -- | 2,396 | -- |
| 16.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,118,644 | -- | 1,924 | -- |
| 16.58% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,094,947 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,986,982.65 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $14,941,500.54 | 14,941,501 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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