BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 12/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/23/2026- NAV $85.69
- NAV Change $-2.52
- Market Price $85.73
- Market Price Change $-2.44
- Trading Volume (M) 9,892
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/23/2026- NAV $85.69
- NAV Change $-2.52
- Market Price $85.73
- Market Price Change $-2.44
- Trading Volume (M) 9,892
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 1/23/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.02% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,412,477.55 | 11,555 | 2931034 |
| 6.01% | GILD | GILEAD SCIENCES INC | -- | $5,411,917.02 | 39,814 | 2369174 |
| 5.56% | AMGN | AMGEN INC | -- | $4,999,909.25 | 14,503 | 2023607 |
| 3.98% | REGN | REGENERON PHARMACEUTICALS | -- | $3,585,390.90 | 4,758 | 2730190 |
| 2.42% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,180,814.16 | 6,092 | B00FWN1 |
| 1.71% | INSM | INSMED INC | -- | $1,534,919.46 | 9,826 | 2614487 |
| 1.29% | BIIB | BIOGEN INC | -- | $1,159,776.81 | 6,759 | 2455965 |
| 1.21% | ARGX | ARGENX SE - ADR | -- | $1,092,566.34 | 1,341 | BDVLM39 |
| 1.18% | ILMN | ILLUMINA INC | -- | $1,057,971.20 | 7,040 | 2613990 |
| 1.16% | RVMD | REVOLUTION MEDICINES INC | -- | $1,047,730.41 | 8,907 | BL71K91 |
| 1.03% | UTHR | UNITED THERAPEUTICS CORP | -- | $930,376.96 | 1,984 | 2430412 |
| 1.03% | INCY | INCYTE CORP | -- | $922,499.55 | 9,045 | 2471950 |
| 0.97% | MRNA | MODERNA INC | -- | $876,731.29 | 17,999 | BGSXTS3 |
| 0.88% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $795,112.40 | 19,681 | BMVP7Y0 |
| 0.85% | MEDP | MEDPACE HOLDINGS INC | -- | $763,876.95 | 1,299 | BDCBC61 |
| 0.80% | ROIV | ROIVANT SCIENCES LTD | -- | $723,689.00 | 32,050 | BMW4NZ9 |
| 0.78% | VTRS | VIATRIS INC | -- | $700,975.44 | 53,064 | BMWS3X9 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $691,329.86 | 8,878 | BK1KWG8 |
| 0.76% | GH | GUARDANT HEALTH INC | -- | $684,024.75 | 5,961 | BFXC911 |
| 0.74% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $665,918.31 | 2,829 | BV9G6B8 |
| 0.70% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $625,610.92 | 4,594 | 2623911 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $599,086.67 | 7,462 | BDJ0LS6 |
| 0.64% | SNY | SANOFI-ADR | -- | $575,462.40 | 12,192 | 2964557 |
| 0.63% | SMMT | SUMMIT THERAPEUTICS INC | -- | $565,574.02 | 34,298 | BMTVQS7 |
| 0.61% | EXEL | EXELIXIS INC | -- | $546,955.85 | 12,355 | 2576941 |
| 0.60% | BNTX | BIONTECH SE-ADR | -- | $540,234.84 | 4,658 | BK6H543 |
| 0.58% | TEM | TEMPUS AI INC | -- | $520,273.80 | 7,965 | BSLSJJ0 |
| 0.56% | RNA | AVIDITY BIOSCIENCES INC | -- | $503,989.20 | 6,942 | BMWHPY1 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $503,511.60 | 1,048 | BD59BS7 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $497,570.92 | 8,852 | 2437071 |
| 0.55% | ONC | BEONE MEDICINES LTD-ADR | -- | $492,014.00 | 1,450 | BYYWPW6 |
| 0.53% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $472,388.00 | 2,800 | B4Q5ZN4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $431,799.12 | 2,322 | BYZR4X4 |
| 0.47% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $419,129.55 | 6,251 | BYQBFJ8 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $376,124.08 | 1,336 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $375,033.96 | 5,418 | 2975098 |
| 0.40% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $359,089.92 | 1,152 | BQ721R4 |
| 0.40% | CYTK | CYTOKINETICS INC | -- | $357,188.53 | 5,633 | BBBSBJ5 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $354,338.76 | 3,329 | BMVBZD3 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $332,044.28 | 2,719 | BLC89B2 |
| 0.36% | CAI | CARIS LIFE SCIENCES INC | -- | $324,975.00 | 12,999 | BT18HP9 |
| 0.35% | PCVX | VAXCYTE INC | -- | $318,014.63 | 6,031 | BKPVGH6 |
| 0.35% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $316,222.38 | 3,074 | BF2YWG4 |
| 0.33% | IBRX | IMMUNITYBIO INC | -- | $292,701.00 | 45,380 | BNSP0B8 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $278,349.75 | 3,699 | B17VCN9 |
| 0.31% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $278,158.86 | 3,078 | BQS9486 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $259,511.00 | 7,075 | BLR6XK8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $255,704.88 | 7,608 | B3P6D26 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $244,010.40 | 4,395 | BDHF4K6 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $239,328.00 | 2,880 | BDCBCD8 |
| 0.26% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $232,609.32 | 4,374 | BDD19F8 |
| 0.26% | KYMR | KYMERA THERAPEUTICS INC | -- | $231,817.95 | 3,315 | BMPRZV5 |
| 0.25% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $223,278.72 | 2,368 | BJDX8Y8 |
| 0.23% | IMVT | IMMUNOVANT INC | -- | $210,108.78 | 8,078 | BJRFSB7 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $209,217.80 | 7,795 | 2713317 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $208,251.58 | 4,702 | BFZQ0L8 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $202,848.05 | 14,215 | B19FQ48 |
| 0.22% | CGON | CG ONCOLOGY INC | -- | $199,957.96 | 3,716 | BRBCSP4 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $193,927.37 | 14,483 | BFNF1D6 |
| 0.21% | -- | INDIVIOR PHARMACEUTICALS INC COMMON STOCK USD 0.001 | -- | $189,709.38 | 5,754 | -- |
| 0.21% | GRAL | GRAIL INC | -- | $188,400.40 | 1,796 | BSLSSX7 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $183,444.45 | 10,965 | B9NSBM2 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $182,443.05 | 907 | 2501578 |
| 0.20% | ACLX | ARCELLX INC | -- | $180,352.80 | 2,664 | BPCJ1Q2 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $176,940.54 | 2,527 | BM9HHL5 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $174,063.68 | 5,224 | BP8JSP4 |
| 0.17% | VCYT | VERACYTE INC | -- | $153,947.34 | 3,642 | BFTWZY0 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $148,749.12 | 3,562 | BRJ3GY4 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $147,846.60 | 5,643 | BKX9VD3 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $147,543.00 | 4,675 | BK6L288 |
| 0.16% | TERN | TERNS PHARMACEUTICALS INC | -- | $142,503.83 | 4,151 | BMDJ0C9 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $140,557.20 | 4,039 | BK0VHF6 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $139,858.05 | 2,945 | BL55460 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $139,559.58 | 4,878 | BKY5JZ8 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $136,829.25 | 6,757 | BD2B4V0 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $133,643.80 | 1,955 | BMH5RL1 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $132,814.20 | 1,740 | BMGJZJ8 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $130,387.95 | 7,029 | BJ5FZ74 |
| 0.14% | ERAS | ERASCA INC | -- | $130,187.16 | 13,071 | BNLYBF3 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $127,476.50 | 2,642 | B72ZBG4 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $126,802.50 | 5,830 | BYTQ6X1 |
| 0.13% | TVTX | TRAVERE THERAPEUTICS INC | -- | $121,351.68 | 4,122 | BLFGJD5 |
| 0.13% | TWST | TWIST BIOSCIENCE CORP | -- | $121,004.92 | 2,818 | BGKG6G7 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $120,158.22 | 5,369 | BKS3RS7 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $119,515.88 | 3,646 | BP9N0G0 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $118,440.00 | 6,580 | BN15WD1 |
| 0.13% | SYRE | SPYRE THERAPEUTICS INC | -- | $114,493.09 | 3,574 | BQBBDY8 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $112,325.15 | 4,445 | BLB0YQ9 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $112,053.70 | 23,690 | BM9FJ13 |
| 0.12% | ALMS | ALUMIS INC | -- | $109,825.08 | 4,479 | BPLQG36 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $107,613.45 | 4,445 | BJ62Z18 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $103,745.94 | 7,702 | BYZG9R0 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $101,994.51 | 4,827 | B8DPDT7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $100,851.40 | 9,820 | BNZB1X8 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $98,146.59 | 2,217 | BSRK699 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $97,720.28 | 2,654 | BKSGZN7 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $91,383.06 | 3,622 | BMZ4LN0 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $91,238.84 | 2,693 | BBC9WC7 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,429.58 | 6,086 | BFWLC09 |
| 0.10% | VCEL | VERICEL CORP | -- | $88,190.50 | 2,330 | BSBMN89 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $87,818.20 | 2,081 | BRXB0C0 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $87,133.28 | 2,056 | BQKXDX4 |
| 0.10% | ARDX | ARDELYX INC | -- | $86,985.15 | 11,195 | BN89V40 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $86,675.20 | 4,670 | BMVLGP2 |
| 0.10% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $86,369.10 | 3,441 | BYP80F1 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $85,894.65 | 1,035 | BCDWBX6 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $83,909.10 | 5,410 | BRJZSK0 |
| 0.09% | PHVS | PHARVARIS NV | -- | $82,568.98 | 2,951 | BMZ2X38 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $81,101.25 | 4,005 | BN7Q7R7 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $80,131.52 | 3,448 | BPCQZY9 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $79,729.84 | 5,059 | BPCK358 |
| 0.09% | -- | DEFINIUM THERAPEUTICS INC COMMON STOCK USD 0 | -- | $78,961.20 | 4,538 | -- |
| 0.09% | MBX | MBX BIOSCIENCES INC | -- | $78,311.65 | 2,069 | BQXJKH2 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $78,124.20 | 5,340 | BYZM6C2 |
| 0.09% | PGEN | PRECIGEN INC | -- | $77,773.64 | 16,339 | BKM5C84 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $77,509.26 | 2,631 | BJQ05Z6 |
| 0.09% | MNKD | MANNKIND CORP | -- | $77,324.52 | 14,162 | BF081J4 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $76,724.09 | 2,231 | BKVF0J2 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $76,658.44 | 2,686 | BCBVTX1 |
| 0.08% | HROW | HARROW INC | -- | $75,910.29 | 1,707 | BHNDW86 |
| 0.08% | ALVO | ALVOTECH SA | -- | $75,859.72 | 14,422 | BPNTJ34 |
| 0.08% | UPB | UPSTREAM BIO INC | -- | $74,749.80 | 2,490 | BRCFFK6 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $74,679.83 | 2,459 | BMVNDH9 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $73,739.79 | 3,879 | BMX9K07 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $73,593.51 | 1,277 | BTJZB49 |
| 0.08% | TNGX | TANGO THERAPEUTICS INC | -- | $72,660.55 | 6,205 | BP2P6L0 |
| 0.08% | QURE | UNIQURE NV | -- | $71,979.60 | 2,870 | BJFSR88 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $71,645.31 | 4,257 | BRXYZ57 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $70,571.10 | 2,010 | BLCD809 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $70,482.52 | 2,734 | BMFD115 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $69,441.95 | 16,733 | BWJDYK1 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $69,388.55 | 5,159 | BYSS4X4 |
| 0.08% | NVAX | NOVAVAX INC | -- | $68,655.79 | 7,487 | BJDQXG4 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $68,520.00 | 3,000 | BP7KZP7 |
| 0.07% | INVA | INNOVIVA INC | -- | $67,384.20 | 3,445 | BDDXF67 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $66,248.00 | 1,456 | BX7RSN3 |
| 0.07% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $65,863.00 | 9,700 | 2100362 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $63,201.84 | 2,444 | BFXC933 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $60,661.04 | 1,276 | BDRW1L7 |
| 0.07% | RLAY | RELAY THERAPEUTICS INC | -- | $59,365.70 | 7,990 | BN2R582 |
| 0.07% | SANA | SANA BIOTECHNOLOGY INC | -- | $59,273.76 | 12,272 | BMFJJ97 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $59,057.49 | 2,193 | BR3T9B6 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $59,020.92 | 5,908 | BJH9ZN0 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $58,809.20 | 12,620 | BNC1BX1 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $58,473.84 | 13,791 | BL53SR3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $57,972.42 | 3,819 | BMGS7L1 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $56,871.36 | 7,644 | BLR7H87 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $56,812.80 | 1,345 | BKLCWZ3 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $56,535.45 | 4,731 | BLB0YH0 |
| 0.06% | SVRA | SAVARA INC | -- | $56,431.48 | 9,374 | BYXGN81 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $54,872.64 | 2,117 | BNFWZS4 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $53,799.13 | 4,487 | BKVDFF7 |
| 0.06% | SEPN | SEPTERNA INC | -- | $53,153.20 | 2,063 | BQNKXX2 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $51,825.62 | 5,621 | B8K7T65 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,022.20 | 670 | BNSP8K3 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $49,803.11 | 2,479 | BQB42H3 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $48,494.16 | 18,369 | BF0DMK7 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $48,459.60 | 6,410 | BK4PZ38 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $47,814.34 | 2,858 | BP6C0S2 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $47,240.16 | 2,334 | BMNDK09 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $46,496.34 | 4,554 | BMCR7V2 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,116.61 | 3,287 | BMG99Y1 |
| 0.05% | ANNX | ANNEXON INC | -- | $45,317.52 | 6,684 | BMVV9R5 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $44,334.00 | 3,284 | BJLKVS6 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,154.93 | 1,902 | BMGTLY5 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $43,328.34 | 7,821 | BYWVTY5 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $43,140.00 | 2,157 | BZ7PJQ1 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $42,285.24 | 2,526 | BQB42F1 |
| 0.05% | XNCR | XENCOR INC | -- | $42,046.20 | 3,290 | BGCYWN8 |
| 0.05% | PSNL | PERSONALIS INC | -- | $41,605.47 | 4,091 | BJQ0608 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $41,520.42 | 2,259 | BQS7491 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $41,038.51 | 2,771 | BMFX8Y7 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $40,967.94 | 1,982 | B3X26D8 |
| 0.05% | GERN | GERON CORP | -- | $40,585.80 | 29,410 | 2370381 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $39,109.94 | 7,478 | B3MZ6K5 |
| 0.04% | OMER | OMEROS CORP | -- | $38,975.31 | 3,267 | B4NB858 |
| 0.04% | ARVN | ARVINAS INC | -- | $38,141.51 | 2,959 | BDZ30Q0 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $37,326.60 | 2,330 | BD06CS0 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $36,888.61 | 8,327 | BPBJFM7 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $36,747.42 | 942 | BL95N25 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,060.92 | 8,882 | BZ0QMB7 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $35,887.80 | 13,910 | B4N8MH9 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,597.67 | 4,009 | BYZD465 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $34,583.96 | 11,014 | BBNBTD2 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,025.00 | 2,722 | BM90J52 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $33,048.99 | 1,803 | BD9GVY0 |
| 0.04% | RGNX | REGENXBIO INC | -- | $32,158.28 | 2,332 | BZ0G875 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $31,124.97 | 4,341 | BMC3HS7 |
| 0.03% | BIOA | BIOAGE LABS INC | -- | $31,074.12 | 1,652 | BT9K6D8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $30,935.52 | 837 | BQD3J33 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,042.90 | 3,709 | BFYQFJ2 |
| 0.03% | LENZ | LENZ THERAPEUTICS INC | -- | $29,454.04 | 1,441 | BQV0J03 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $28,849.50 | 10,685 | BJ0CK86 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $27,863.94 | 3,614 | BDDVW37 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $26,956.80 | 1,404 | BM7V485 |
| 0.03% | IVVD | INVIVYD INC | -- | $26,938.37 | 12,767 | BM8NHS1 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $26,799.75 | 2,493 | BJDX8Z9 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $26,712.32 | 2,624 | BMFK3H6 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $26,444.00 | 4,808 | BFY7DC4 |
| 0.03% | CRMD | CORMEDIX INC | -- | $26,390.10 | 3,630 | BJ0LT31 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $25,215.00 | 3,362 | BQ6C357 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,800.00 | 2,480 | B91XRN2 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $24,786.51 | 6,681 | BMCWKZ2 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $24,704.28 | 978 | BTNMG41 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,687.40 | 3,589 | BQHN6C7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,268.18 | 2,594 | BLFBZ32 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $22,910.40 | 666 | B292NQ7 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $22,464.00 | 4,992 | BYV2W40 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,905.36 | 3,299 | 2107437 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $21,811.23 | 2,723 | B12W3P6 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $21,676.46 | 4,121 | BYTYP72 |
| 0.02% | KMDA | KAMADA LTD | -- | $21,051.36 | 2,658 | B2Q9833 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,950.72 | 2,632 | BKLXFX5 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,160.48 | 6,928 | BN94K69 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,128.23 | 1,761 | BP81RK8 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $19,695.68 | 2,018 | BSMLR16 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $18,633.10 | 4,790 | BKRRKY7 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,547.92 | 4,986 | BDFKQ07 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $18,512.65 | 1,235 | BGL0JK3 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $18,212.04 | 5,621 | BYVQJ96 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $17,808.88 | 10,354 | BFZNYB7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $17,377.92 | 862 | BPBPCG8 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,316.60 | 1,330 | B9L5200 |
| 0.02% | PEPG | PEPGEN INC | -- | $17,260.15 | 3,167 | BMTX3D7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $17,116.20 | 4,626 | BZC0D70 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,619.68 | 2,926 | BP81R42 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,967.44 | 2,979 | BMVBZF5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,857.88 | 7,698 | BN4JN37 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,686.00 | 2,530 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,323.28 | 2,606 | BMF7DT9 |
| 0.02% | AARD | AARDVARK THERAPEUTICS INC | -- | $15,055.03 | 1,003 | BTXQTX3 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,900.82 | 2,321 | B7F2TY6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,827.88 | 3,599 | BLN9Z50 |
| 0.02% | LFCR | LIFECORE BIOMEDICAL INC | -- | $14,817.66 | 1,727 | 2517058 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $14,817.40 | 2,132 | BKDQKM6 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,691.12 | 2,986 | BDRJH21 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,549.67 | 3,943 | BMXNGZ6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $14,103.30 | 4,435 | BK5MWR1 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,834.35 | 1,065 | BPRBTY7 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,493.32 | 9,242 | BFMLGR4 |
| 0.01% | NGNE | NEUROGENE INC | -- | $13,055.03 | 713 | BS2F741 |
| 0.01% | OABI | OMNIAB INC | -- | $13,000.68 | 6,633 | BN13S71 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $12,873.84 | 776 | BRJJYT3 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $12,269.88 | 2,164 | BL5B6Z1 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,472.14 | 5,569 | BRK0149 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $11,261.25 | 9,009 | BNR5QT9 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,876.00 | 2,719 | BY7RB53 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $10,611.06 | 3,502 | BPTK6Z2 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,512.08 | 2,602 | BPRB2N7 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,856.77 | 1,309 | BKC9SX3 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,715.68 | 4,498 | BZ8FPH3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,599.75 | 4,465 | BKX9NQ0 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,059.40 | 8,628 | BMYTJP4 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,786.34 | 1,431 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,187.12 | 2,466 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,990.48 | 4,161 | B5LL2C2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,851.25 | 2,625 | BKTV702 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,588.18 | 4,306 | BNYJR68 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,246.66 | 4,494 | BNNXX18 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,602.86 | 7,672 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,676.47 | 2,869 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $15.05 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 41.56% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,395,525 | -- | 6,299 | -- |
| 29.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,293,821 | -- | 4,429 | -- |
| 23.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,235,719 | -- | 3,577 | -- |
| 17.41% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,667,057 | -- | 2,639 | -- |
| 16.39% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,746,862 | -- | 2,484 | -- |
| 4.18% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,757,956 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,714,967.17 | 28,714,967 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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