BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 10/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 4.67% | 24.99% | 47.98% | 51.34% | 69.14% | 43.98% | 6.41% | 12.60% | 18.47% | 04/07/2010 |
| BIB Market Price | 4.40% | 24.85% | 47.78% | 51.20% | 68.94% | 43.92% | 6.39% | 12.57% | 18.46% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -0.91% | 14.69% | 41.74% | 44.83% | 94.28% | 35.26% | 4.58% | 9.38% | 18.26% | 04/07/2010 |
| BIB NAV | -1.01% | 14.41% | 41.46% | 44.59% | 93.99% | 35.10% | 4.57% | 9.35% | 18.24% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $107,693,254
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/04/2026- NAV
- NAV Change
- Market Price $125.11
- Market Price Change $+6.34
- Trading Volume (M) 8,336
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $107,693,254
- Gross Expense Ratio 1.17%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 11/04/2026- NAV
- NAV Change
- Market Price $125.11
- Market Price Change $+6.34
- Trading Volume (M) 8,336
- 30-Day Median Bid Ask Spread 0.26%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2027. Without the fee waiver performance would likely be lower.
Exposures
Index as of 9/30/2026
Holdings
as of 11/04/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.49% | GILD | GILEAD SCIENCES INC | -- | $5,910,858.96 | 33,877 | 2369174 |
| 5.12% | AMGN | AMGEN INC | -- | $5,517,831.36 | 11,532 | 2023607 |
| 4.64% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,998,460.16 | 9,104 | 2931034 |
| 3.89% | MRNA | MODERNA INC | -- | $4,186,014.38 | 16,201 | BGSXTS3 |
| 3.55% | REGN | REGENERON PHARMACEUTICALS | -- | $3,819,469.68 | 4,104 | 2730190 |
| 1.61% | RVMD | REVOLUTION MEDICINES INC | -- | $1,736,990.60 | 8,698 | BL71K91 |
| 1.42% | BIIB | BIOGEN INC | -- | $1,525,742.16 | 5,996 | 2455965 |
| 1.29% | ILMN | ILLUMINA INC | -- | $1,388,237.12 | 6,128 | 2613990 |
| 1.13% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $1,220,741.64 | 18,069 | BMVP7Y0 |
| 1.04% | ROIV | ROIVANT SCIENCES LTD | -- | $1,120,597.76 | 29,312 | BMW4NZ9 |
| 0.98% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,059,381.09 | 1,741 | 2430412 |
| 0.96% | ARGX | ARGENX SE - ADR | -- | $1,031,037.66 | 1,107 | BDVLM39 |
| 0.94% | INCY | INCYTE CORP | -- | $1,010,441.25 | 8,225 | 2471950 |
| 0.91% | INSM | INSMED INC | -- | $974,820.00 | 8,862 | 2614487 |
| 0.85% | GH | GUARDANT HEALTH INC | -- | $918,086.68 | 5,446 | BFXC911 |
| 0.83% | VTRS | VIATRIS INC | -- | $895,844.20 | 46,610 | BMWS3X9 |
| 0.81% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $874,664.40 | 5,430 | B00FWN1 |
| 0.69% | MEDP | MEDPACE HOLDINGS INC | -- | $744,120.41 | 1,133 | BDCBC61 |
| 0.68% | EXEL | EXELIXIS INC | -- | $731,501.25 | 10,055 | 2576941 |
| 0.64% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $684,956.25 | 4,125 | 2623911 |
| 0.60% | ASND | ASCENDIS PHARMA A/S | -- | $644,309.14 | 2,498 | BWXJHM8 |
| 0.59% | BBIO | BRIDGEBIO PHARMA INC | -- | $633,713.04 | 8,136 | BK1KWG8 |
| 0.57% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $618,094.44 | 2,634 | B4Q5ZN4 |
| 0.56% | HALO | HALOZYME THERAPEUTICS INC | -- | $600,346.04 | 4,606 | 2975098 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $549,669.90 | 1,455 | BYYWPW6 |
| 0.50% | TEM | TEMPUS AI INC-CL A | -- | $538,116.37 | 7,117 | BSLSJJ0 |
| 0.49% | SMMT | SUMMIT THERAPEUTICS INC | -- | $523,471.41 | 32,373 | BMTVQS7 |
| 0.43% | KYMR | KYMERA THERAPEUTICS INC | -- | $459,707.50 | 3,374 | BMPRZV5 |
| 0.42% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $448,756.15 | 7,855 | 2437071 |
| 0.40% | BNTX | BIONTECH SE-ADR | -- | $426,199.30 | 4,699 | BK6H543 |
| 0.39% | SNY | SANOFI-ADR | -- | $415,267.56 | 8,748 | 2964557 |
| 0.37% | PCVX | VAXCYTE INC | -- | $396,641.52 | 6,039 | BKPVGH6 |
| 0.36% | IBRX | IMMUNITYBIO INC | -- | $384,061.44 | 43,008 | BNSP0B8 |
| 0.36% | TWST | TWIST BIOSCIENCE CORP | -- | $383,825.36 | 2,692 | BGKG6G7 |
| 0.35% | CAI | CARIS LIFE SCIENCES INC | -- | $380,966.96 | 11,468 | BT18HP9 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $376,489.62 | 2,626 | BDCBCD8 |
| 0.35% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $375,603.34 | 938 | BD59BS7 |
| 0.35% | KRYS | KRYSTAL BIOTECH INC | -- | $373,318.84 | 1,201 | BD6JX35 |
| 0.33% | CYTK | CYTOKINETICS INC | -- | $358,831.20 | 5,642 | BBBSBJ5 |
| 0.33% | SYRE | SPYRE THERAPEUTICS INC | -- | $354,365.12 | 3,578 | BQBBDY8 |
| 0.33% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $353,377.80 | 5,732 | BYQBFJ8 |
| 0.31% | TXG | 10X GENOMICS INC-CLASS A | -- | $329,362.56 | 4,878 | BKS3RS7 |
| 0.30% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $322,667.07 | 1,133 | BQ721R4 |
| 0.29% | ALKS | ALKERMES PLC | -- | $312,419.12 | 6,808 | B3P6D26 |
| 0.29% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $309,239.92 | 2,794 | BF2YWG4 |
| 0.27% | AXSM | AXSOME THERAPEUTICS INC | -- | $291,262.00 | 2,126 | BYZR4X4 |
| 0.26% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $281,973.30 | 14,134 | BFNF1D6 |
| 0.25% | ORKA | ORUKA THERAPEUTICS INC | -- | $272,488.67 | 2,687 | BKVF0J2 |
| 0.25% | IONS | IONIS PHARMACEUTICALS INC | -- | $270,771.60 | 6,744 | BDJ0LS6 |
| 0.24% | GRAL | GRAIL INC | -- | $260,455.58 | 1,813 | BSLSSX7 |
| 0.24% | LGND | LIGAND PHARMACEUTICALS | -- | $255,749.17 | 809 | 2501578 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $255,515.95 | 2,635 | BJDX8Y8 |
| 0.23% | KOD | KODIAK SCIENCES INC | -- | $251,200.50 | 2,550 | BFXC933 |
| 0.23% | IMVT | IMMUNOVANT INC | -- | $250,621.80 | 8,382 | BJRFSB7 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $243,552.87 | 3,597 | BRBCSP4 |
| 0.22% | SUPN | SUPERNUS INC | -- | $237,584.62 | 8,422 | BTZRLN8 |
| 0.22% | PTCT | PTC THERAPEUTICS INC | -- | $233,601.39 | 3,387 | B17VCN9 |
| 0.21% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $227,776.78 | 4,942 | BFZQ0L8 |
| 0.21% | COGT | COGENT BIOSCIENCES INC | -- | $221,752.58 | 7,042 | BLR6XK8 |
| 0.20% | GMAB | GENMAB A/S -SP ADR | -- | $216,897.20 | 3,935 | BBC9WC7 |
| 0.20% | ERAS | ERASCA INC | -- | $211,617.63 | 14,193 | BNLYBF3 |
| 0.19% | ABVX | ABIVAX SA-ADR | -- | $207,616.80 | 2,320 | BLC89B2 |
| 0.19% | CRSP | CRISPR THERAPEUTICS AG | -- | $203,165.10 | 3,924 | BDHF4K6 |
| 0.19% | TVTX | TRAVERE THERAPEUTICS INC | -- | $200,506.50 | 3,825 | BLFGJD5 |
| 0.17% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $188,395.20 | 1,960 | BRXB0C0 |
| 0.17% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $178,313.10 | 5,453 | BV2DHY6 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $173,689.05 | 5,101 | BKX9VD3 |
| 0.16% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $172,973.96 | 6,476 | BJ5FZ74 |
| 0.16% | VCYT | VERACYTE INC | -- | $171,320.24 | 3,262 | BFTWZY0 |
| 0.15% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $165,394.71 | 4,407 | BKY5JZ8 |
| 0.15% | ABCL | ABCELLERA BIOLOGICS INC | -- | $161,482.00 | 13,150 | BL53SR3 |
| 0.15% | RLAY | RELAY THERAPEUTICS INC | -- | $160,340.79 | 8,893 | BN2R582 |
| 0.15% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $159,923.40 | 18,382 | BF0DMK7 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $158,597.56 | 6,842 | BP2P6L0 |
| 0.14% | XENE | XENON PHARMACEUTICALS INC | -- | $154,016.70 | 3,930 | BRJ3GY4 |
| 0.14% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $150,118.24 | 6,992 | 2713317 |
| 0.14% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $149,734.20 | 5,093 | BPCK358 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $140,496.12 | 7,578 | BN15WD1 |
| 0.13% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $140,474.25 | 2,973 | BMFD115 |
| 0.13% | DNLI | DENALI THERAPEUTICS INC | -- | $135,967.52 | 6,487 | BD2B4V0 |
| 0.12% | IRON | DISC MEDICINE INC | -- | $129,750.24 | 1,558 | BMGJZJ8 |
| 0.12% | TARS | TARSUS PHARMACEUTICALS INC | -- | $128,884.62 | 1,866 | BMH5RL1 |
| 0.12% | IDYA | IDEAYA BIOSCIENCES INC | -- | $126,721.76 | 3,916 | BK0VHF6 |
| 0.11% | BEAM | BEAM THERAPEUTICS INC | -- | $116,467.89 | 4,191 | BK6L288 |
| 0.10% | XNCR | XENCOR INC | -- | $105,685.51 | 3,017 | BGCYWN8 |
| 0.10% | MBX | MBX BIOSCIENCES INC | -- | $102,545.92 | 1,954 | BQXJKH2 |
| 0.09% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $101,531.43 | 4,851 | BP8JSP4 |
| 0.09% | PHVS | PHARVARIS NV | -- | $97,806.17 | 2,849 | BMZ2X38 |
| 0.09% | ADMA | ADMA BIOLOGICS INC | -- | $95,252.72 | 9,089 | B9NSBM2 |
| 0.09% | VCEL | VERICEL CORP | -- | $94,507.44 | 2,078 | BSBMN89 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $93,480.28 | 2,924 | BL55460 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $92,376.89 | 5,399 | BFWLC09 |
| 0.08% | SEPN | SEPTERNA INC | -- | $90,684.72 | 1,894 | BQNKXX2 |
| 0.08% | ZYME | ZYMEWORKS INC | -- | $89,107.20 | 2,880 | BPCQZY9 |
| 0.08% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $85,448.80 | 10,370 | 2100362 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $85,114.26 | 3,738 | BMX9K07 |
| 0.08% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $84,289.12 | 21,724 | BM9FJ13 |
| 0.08% | SRPT | SAREPTA THERAPEUTICS INC | -- | $81,391.14 | 4,286 | B8DPDT7 |
| 0.08% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $81,322.65 | 2,363 | BKSGZN7 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $80,861.27 | 5,782 | BJH9ZN0 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $80,824.59 | 6,867 | BK4PZ38 |
| 0.07% | FTRE | FORTREA HOLDINGS INC | -- | $80,382.97 | 3,859 | BRXYZ57 |
| 0.07% | REPL | REPLIMUNE GROUP INC | -- | $79,097.87 | 3,823 | BDDVW37 |
| 0.07% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $77,393.54 | 7,399 | BLR7H87 |
| 0.07% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $76,033.74 | 2,423 | BCBVTX1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $75,276.70 | 2,645 | BQB42H3 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $75,238.52 | 2,254 | BSRK699 |
| 0.07% | PGEN | PRECIGEN INC | -- | $73,444.10 | 14,529 | BKM5C84 |
| 0.07% | ABSI | ABSCI CORP | -- | $72,982.72 | 6,964 | BN94K69 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $71,864.10 | 2,618 | BJQ05Z6 |
| 0.07% | NVAX | NOVAVAX INC | -- | $71,280.45 | 6,693 | BJDQXG4 |
| 0.07% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $71,108.00 | 1,450 | BS2CR64 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,994.66 | 5,686 | BYZM6C2 |
| 0.06% | NVCR | NOVOCURE LTD | -- | $69,032.25 | 4,725 | BYSS4X4 |
| 0.06% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $68,657.16 | 4,001 | BJ62Z18 |
| 0.06% | PSNL | PERSONALIS INC | -- | $68,433.86 | 4,334 | BJQ0608 |
| 0.06% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $67,717.36 | 3,326 | BQS9486 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $67,165.45 | 4,211 | BMVLGP2 |
| 0.06% | ANIP | ANI PHARMACEUTICALS INC | -- | $66,777.80 | 932 | BCDWBX6 |
| 0.06% | QURE | UNIQURE NV | -- | $64,829.45 | 2,815 | BJFSR88 |
| 0.06% | ALVO | ALVOTECH SA | -- | $64,095.75 | 13,725 | BPNTJ34 |
| 0.06% | OCUL | OCULAR THERAPEUTIX INC | -- | $63,631.68 | 8,912 | BNZB1X8 |
| 0.06% | INVA | INNOVIVA INC | -- | $62,334.32 | 2,932 | BDDXF67 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $60,996.00 | 3,588 | BP9N0G0 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $58,895.20 | 1,618 | B3X26D8 |
| 0.05% | ETON | ETON PHARMACEUTICALS INC | -- | $58,835.20 | 1,160 | BGL0JK3 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $57,647.92 | 13,222 | BNC1BX1 |
| 0.05% | ANAB | ANAPTYSBIO INC | -- | $57,107.02 | 1,202 | BDRW1L7 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $57,020.16 | 1,984 | BZ7PJQ1 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $55,524.98 | 2,786 | BP6C0S2 |
| 0.05% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $54,952.40 | 1,880 | BLCD809 |
| 0.05% | OMER | OMEROS CORP | -- | $53,412.84 | 2,938 | B4NB858 |
| 0.05% | TYRA | TYRA BIOSCIENCES INC | -- | $52,133.55 | 2,422 | BMVNDH9 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $51,795.72 | 597 | BNSP8K3 |
| 0.05% | MNKD | MANNKIND CORP | -- | $51,278.64 | 13,048 | BF081J4 |
| 0.05% | RAPP | RAPPORT THERAPEUTICS INC | -- | $50,485.71 | 1,947 | BR3T9B6 |
| 0.04% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $48,362.52 | 1,726 | BNFWZS4 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $48,308.12 | 2,401 | BRJJYT3 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $46,732.40 | 5,434 | BMC3HS7 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $46,675.12 | 6,046 | BMCWKZ2 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $45,104.58 | 2,481 | BMFX8Y7 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $44,330.00 | 1,240 | BKLCWZ3 |
| 0.04% | HROW | HARROW INC | -- | $43,728.75 | 1,521 | BHNDW86 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $41,222.40 | 1,808 | BD9GVY0 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,284.04 | 4,206 | BKVDFF7 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $38,877.82 | 758 | BQD3J33 |
| 0.04% | SVRA | SAVARA INC | -- | $38,855.08 | 8,338 | BYXGN81 |
| 0.04% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $37,870.80 | 3,624 | BN7Q7R7 |
| 0.04% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $37,758.60 | 1,907 | BL5B6Z1 |
| 0.03% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $37,458.84 | 3,462 | BP7KZP7 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $36,709.74 | 3,897 | BFYQFJ2 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $36,579.20 | 7,360 | BPBJFM7 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $36,085.98 | 3,414 | BYP80F1 |
| 0.03% | ALMS | ALUMIS INC | -- | $34,400.60 | 5,252 | BPLQG36 |
| 0.03% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $33,752.08 | 856 | BL95N25 |
| 0.03% | ANNX | ANNEXON INC | -- | $33,310.69 | 7,693 | BMVV9R5 |
| 0.03% | ARDX | ARDELYX INC | -- | $33,268.48 | 10,112 | BN89V40 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $32,623.88 | 2,612 | BM90J52 |
| 0.03% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,597.74 | 8,029 | BZ0QMB7 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $32,165.70 | 12,614 | B4N8MH9 |
| 0.03% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $31,268.07 | 1,321 | BX7RSN3 |
| 0.03% | SANA | SANA BIOTECHNOLOGY INC | -- | $31,098.88 | 12,148 | BMFJJ97 |
| 0.03% | OABI | OMNIAB INC | -- | $30,562.00 | 5,900 | BN13S71 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $30,409.12 | 2,128 | BQS7491 |
| 0.03% | WVE | WAVE LIFE SCIENCES INC | -- | $28,945.52 | 7,996 | C08GM13 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $28,368.52 | 4,351 | BQHN6C7 |
| 0.03% | GERN | GERON CORP | -- | $28,157.76 | 26,072 | 2370381 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $28,100.25 | 3,105 | BP0TQC5 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $27,983.20 | 4,208 | BP81R42 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $27,531.76 | 2,242 | BKLXFX5 |
| 0.03% | KURA | KURA ONCOLOGY INC | -- | $27,472.10 | 3,610 | BYZD465 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,000.20 | 2,540 | BMFK3H6 |
| 0.03% | AVBP | ARRIVENT BIOPHARMA INC | -- | $26,993.49 | 2,001 | BMGTLY5 |
| 0.02% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $26,919.70 | 2,410 | BLFBZ32 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $26,774.54 | 3,551 | BMZ4LN0 |
| 0.02% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,277.85 | 6,705 | B3MZ6K5 |
| 0.02% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $24,965.01 | 2,499 | BP2NYN2 |
| 0.02% | BCAX | BICARA THERAPEUTICS INC | -- | $23,869.65 | 2,685 | BQB42F1 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $22,395.55 | 2,095 | B7F2TY6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $22,394.96 | 812 | BS2F741 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,980.64 | 5,973 | BYV2W40 |
| 0.02% | CTMX | CYTOMX THERAPEUTICS INC | -- | $20,778.70 | 8,842 | BYWVTY5 |
| 0.02% | RGNX | REGENXBIO INC | -- | $20,655.09 | 2,679 | BZ0G875 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $20,590.36 | 604 | B292NQ7 |
| 0.02% | EOLS | EVOLUS INC | -- | $20,019.60 | 2,680 | BDRJH21 |
| 0.02% | ARVN | ARVINAS INC | -- | $19,685.26 | 2,653 | BDZ30Q0 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,353.40 | 5,093 | BYVQJ96 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $18,647.44 | 3,283 | BJLKVS6 |
| 0.02% | CRMD | CORMEDIX INC | -- | $17,902.58 | 3,163 | BJ0LT31 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $17,476.37 | 2,083 | B91XRN2 |
| 0.02% | KMDA | KAMADA LTD | -- | $17,370.22 | 2,341 | B2Q9833 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $16,951.04 | 6,232 | BZ8FPH3 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,735.28 | 7,894 | BFY7DC4 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,683.80 | 14,020 | BFZNYB7 |
| 0.01% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,097.90 | 793 | BPBPCG8 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $16,059.23 | 2,179 | BP7L561 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $15,575.04 | 4,992 | BKX9NQ0 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $15,337.42 | 994 | BTNMG41 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $14,634.00 | 2,439 | BPRB2N7 |
| 0.01% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,517.30 | 3,255 | BLN9Z50 |
| 0.01% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,089.23 | 1,337 | BPRBTY7 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $12,951.60 | 2,510 | BSMLR16 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $12,588.30 | 1,182 | B9L5200 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $12,533.11 | 1,153 | BKC9SX3 |
| 0.01% | SPRY | ARS PHARMACEUTICALS INC | -- | $12,309.80 | 4,036 | BMCR7V2 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $11,671.92 | 3,096 | BJDX8Z9 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $11,636.16 | 4,216 | BMXNGZ6 |
| 0.01% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,627.55 | 4,455 | BDFKQ07 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,233.20 | 8,140 | BFMLGR4 |
| 0.01% | BIOA | BIOAGE LABS INC | -- | $11,078.90 | 1,862 | BT9K6D8 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $10,752.67 | 3,329 | BQ6C357 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $10,414.17 | 8,073 | BNR5QT9 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $9,891.84 | 1,536 | 2517058 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,870.00 | 2,625 | BMVBZF5 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $9,769.60 | 6,880 | BK5MWR1 |
| 0.01% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,521.52 | 2,454 | B12W3P6 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $9,457.70 | 4,130 | BZC0D70 |
| 0.01% | SIGA | SIGA TECHNOLOGIES INC | -- | $9,185.40 | 2,916 | 2107437 |
| 0.01% | KROS | KEROS THERAPEUTICS INC | -- | $8,718.15 | 805 | BM7V485 |
| 0.01% | UPB | UPSTREAM BIO INC | -- | $8,225.10 | 2,223 | BRCFFK6 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,994.80 | 1,580 | BP81RK8 |
| 0.01% | IVVD | INVIVYD INC | -- | $7,578.49 | 11,961 | BM8NHS1 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,053.12 | 1,896 | BKDQKM6 |
| 0.01% | PEPG | PEPGEN INC | -- | $6,886.95 | 2,811 | BMTX3D7 |
| 0.01% | SION | SIONNA THERAPEUTICS INC | -- | $6,844.55 | 1,835 | BQKXDX4 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $5,619.10 | 3,385 | BLBR8D5 |
| -- | MENS | JYONG BIOTECH LTD | -- | $5,367.90 | 3,085 | BPTK6Z2 |
| -- | CHRS | COHERUS ONCOLOGY INC | -- | $5,330.75 | 6,270 | BRK0149 |
| -- | HUMA | HUMACYTE INC | -- | $5,072.85 | 11,273 | BMYTJP4 |
| -- | FHTX | FOGHORN THERAPEUTICS INC | -- | $5,061.00 | 2,410 | BMF7DT9 |
| -- | CDXS | CODEXIS INC | -- | $4,799.52 | 4,444 | B5LL2C2 |
| -- | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $4,740.12 | 3,762 | BYTYP72 |
| -- | VYGR | VOYAGER THERAPEUTICS INC | -- | $4,675.00 | 2,500 | BY7RB53 |
| -- | NBP | NOVABRIDGE BIOSCIENCES | -- | $4,600.55 | 4,555 | BKRRKY7 |
| -- | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $4,428.90 | 2,331 | BKTV702 |
| -- | LENZ | LENZ THERAPEUTICS INC | -- | $4,411.50 | 1,275 | BQV0J03 |
| -- | NMRA | NEUMORA THERAPEUTICS INC | -- | $4,315.75 | 7,625 | BN4JN37 |
| -- | TNYA | TENAYA THERAPEUTICS INC | -- | $3,365.72 | 9,099 | BNNXX52 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $2,683.00 | 4,684 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $2,467.60 | 248 | C0BCTT5 |
| -- | CRBU | CARIBOU BIOSCIENCES INC | -- | $1,933.14 | 4,350 | BNYJR68 |
| -- | EYPT | EYEPOINT INC | -- | $1,381.71 | 3,498 | BMGS7L1 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $1,118.88 | 888 | BTXQTX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | -- | COHERUS ONCOLOGY INC COMMON STOCK USD | -- | $00.00 | 5,356 | -- |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 35.21% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 37,915,494 | -- | 5,080 | -- |
| 32.28% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 34,765,821 | -- | 4,658 | -- |
| 31.98% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 34,444,883 | -- | 4,615 | -- |
| 18.29% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 19,696,652 | -- | 2,639 | -- |
| 17.42% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 18,756,228 | -- | 2,513 | -- |
| 4.36% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 4,694,655 | -- | 629 | -- |
| -- | IQMM | PROSHARES GENIUS MONEY MARKET ETF | -- | $17,015,300.00 | 170,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,816,877.30 | 25,816,877 | -- |
Index
as of 9/30/2026
- Total Number of Holdings245
- Price/Book Ratio6.08
- Dividend Yield ( % )0.49
- Avg. Index Market Capitalization$7.91 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: Why hedge?—A tool for managing risk
Periods of uncertainty often make investors want to reduce risk in their portfolios. A hedging strategy may help investors manage risk while remaining invested for long-term growth.
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