BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,891,032
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/08/2026- NAV
- NAV Change
- Market Price $83.66
- Market Price Change $+3.08
- Trading Volume (M) 5,096
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $82,891,032
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/08/2026- NAV
- NAV Change
- Market Price $83.66
- Market Price Change $+3.08
- Trading Volume (M) 5,096
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 4/08/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.28% | GILD | GILEAD SCIENCES INC | -- | $4,374,293.70 | 30,905 | 2369174 |
| 5.01% | AMGN | AMGEN INC | -- | $4,148,746.60 | 11,860 | 2023607 |
| 4.96% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,112,918.80 | 9,265 | 2931034 |
| 4.35% | REGN | REGENERON PHARMACEUTICALS | -- | $3,603,887.91 | 4,647 | 2730190 |
| 2.34% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,941,247.00 | 5,932 | B00FWN1 |
| 1.86% | INSM | INSMED INC | -- | $1,544,455.56 | 9,642 | 2614487 |
| 1.42% | BIIB | BIOGEN INC | -- | $1,180,863.60 | 6,564 | 2455965 |
| 1.38% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,140,112.40 | 1,960 | 2430412 |
| 1.20% | ARGX | ARGENX SE - ADR | -- | $996,253.83 | 1,269 | BDVLM39 |
| 1.11% | MRNA | MODERNA INC | -- | $920,450.70 | 17,667 | BGSXTS3 |
| 1.11% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $918,003.50 | 19,165 | BMVP7Y0 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $901,918.89 | 32,017 | BMW4NZ9 |
| 1.06% | ILMN | ILLUMINA INC | -- | $875,648.00 | 6,841 | 2613990 |
| 1.03% | RVMD | REVOLUTION MEDICINES INC | -- | $857,688.75 | 8,865 | BL71K91 |
| 1.03% | INCY | INCYTE CORP | -- | $853,612.78 | 8,902 | 2471950 |
| 0.84% | VTRS | VIATRIS INC | -- | $698,949.99 | 51,507 | BMWS3X9 |
| 0.80% | MEDP | MEDPACE HOLDINGS INC | -- | $660,704.85 | 1,269 | BDCBC61 |
| 0.79% | SMMT | SUMMIT THERAPEUTICS INC | -- | $652,443.66 | 34,686 | BMTVQS7 |
| 0.78% | BBIO | BRIDGEBIO PHARMA INC | -- | $643,016.22 | 8,673 | BK1KWG8 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $642,232.80 | 2,754 | BV9G6B8 |
| 0.72% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $597,843.50 | 4,490 | 2623911 |
| 0.67% | IONS | IONIS PHARMACEUTICALS INC | -- | $554,102.20 | 7,390 | BDJ0LS6 |
| 0.66% | GH | GUARDANT HEALTH INC | -- | $544,692.28 | 5,867 | BFXC911 |
| 0.65% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $539,591.22 | 2,754 | B4Q5ZN4 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $533,783.25 | 1,027 | BD59BS7 |
| 0.62% | SNY | SANOFI-ADR | -- | $516,135.86 | 10,949 | 2964557 |
| 0.62% | EXEL | EXELIXIS INC | -- | $513,471.40 | 11,617 | 2576941 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $492,148.80 | 8,604 | 2437071 |
| 0.57% | BNTX | BIONTECH SE-ADR | -- | $469,239.68 | 5,096 | BK6H543 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $446,431.70 | 1,430 | BYYWPW6 |
| 0.49% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $403,215.40 | 6,265 | BYQBFJ8 |
| 0.48% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $398,673.90 | 1,245 | BQ721R4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $396,431.91 | 2,289 | BYZR4X4 |
| 0.47% | PCVX | VAXCYTE INC | -- | $386,923.80 | 6,438 | BKPVGH6 |
| 0.45% | TEM | TEMPUS AI INC-CL A | -- | $369,122.50 | 7,771 | BSLSJJ0 |
| 0.44% | CYTK | CYTOKINETICS INC | -- | $362,326.93 | 5,509 | BBBSBJ5 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $345,863.98 | 1,309 | BD6JX35 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $345,470.40 | 5,280 | 2975098 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $343,900.96 | 3,274 | BMVBZD3 |
| 0.39% | ABVX | ABIVAX SA-ADR | -- | $326,902.08 | 2,748 | BLC89B2 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $321,017.18 | 45,991 | BNSP0B8 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $318,111.63 | 3,651 | BMPRZV5 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $291,466.95 | 2,855 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $268,293.95 | 7,261 | BLR6XK8 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $264,367.05 | 2,699 | BJDX8Y8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $263,875.78 | 3,703 | B17VCN9 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $261,141.40 | 3,055 | BF2YWG4 |
| 0.31% | CGON | CG ONCOLOGY INC | -- | $260,190.86 | 3,778 | BRBCSP4 |
| 0.31% | ALKS | ALKERMES PLC | -- | $259,210.35 | 7,455 | B3P6D26 |
| 0.30% | TERN | TERNS PHARMACEUTICALS INC | -- | $250,503.62 | 4,757 | BMDJ0C9 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $246,255.22 | 12,622 | BT18HP9 |
| 0.28% | ERAS | ERASCA INC | -- | $234,619.00 | 13,850 | BNLYBF3 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $232,665.42 | 5,718 | BYTQ6X1 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $228,154.36 | 4,564 | BFZQ0L8 |
| 0.27% | IMVT | IMMUNOVANT INC | -- | $225,191.38 | 9,106 | BJRFSB7 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $222,205.68 | 4,293 | BDHF4K6 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $214,163.88 | 3,722 | BRJ3GY4 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $211,525.03 | 5,351 | BLB0YQ9 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $203,810.24 | 2,452 | BM9HHL5 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $187,172.64 | 4,684 | BDD19F8 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $185,408.19 | 891 | 2501578 |
| 0.22% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $185,088.35 | 3,485 | BQS9486 |
| 0.22% | SYRE | SPYRE THERAPEUTICS INC | -- | $182,605.74 | 3,513 | BQBBDY8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $178,905.96 | 14,076 | BFNF1D6 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $178,672.36 | 5,594 | BTZRLN8 |
| 0.21% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $174,879.42 | 5,142 | BP8JSP4 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $172,042.56 | 7,626 | 2713317 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $158,525.92 | 4,798 | BKY5JZ8 |
| 0.17% | TWST | TWIST BIOSCIENCE CORP | -- | $140,308.14 | 2,742 | BGKG6G7 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $139,203.90 | 7,095 | BD2B4V0 |
| 0.17% | TARS | TARSUS PHARMACEUTICALS INC | -- | $136,806.67 | 1,903 | BMH5RL1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $136,437.84 | 5,544 | BKX9VD3 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $135,368.70 | 7,365 | BN15WD1 |
| 0.16% | ORKA | ORUKA THERAPEUTICS INC | -- | $134,251.65 | 2,165 | BKVF0J2 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $132,379.65 | 2,565 | B72ZBG4 |
| 0.16% | TVTX | TRAVERE THERAPEUTICS INC | -- | $130,743.36 | 4,127 | BLFGJD5 |
| 0.16% | VERA | VERA THERAPEUTICS INC | -- | $128,733.36 | 3,192 | BL55460 |
| 0.15% | ALMS | ALUMIS INC | -- | $128,425.05 | 5,655 | BPLQG36 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $121,641.84 | 3,929 | BK0VHF6 |
| 0.15% | TXG | 10X GENOMICS INC-CLASS A | -- | $121,177.28 | 5,264 | BKS3RS7 |
| 0.15% | TNGX | TANGO THERAPEUTICS INC | -- | $120,861.50 | 6,025 | BP2P6L0 |
| 0.14% | VCYT | VERACYTE INC | -- | $116,141.85 | 3,555 | BFTWZY0 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $116,007.45 | 7,995 | BN2R582 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $115,930.08 | 4,557 | BK6L288 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $114,114.00 | 2,730 | BFXC933 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $114,022.08 | 2,656 | BMFD115 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $113,122.89 | 1,707 | BMGJZJ8 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $109,731.60 | 11,220 | 2100362 |
| 0.13% | ADMA | ADMA BIOLOGICS INC | -- | $104,728.82 | 10,654 | B9NSBM2 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $102,667.20 | 4,688 | B8DPDT7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $102,217.92 | 6,888 | BJ5FZ74 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $100,077.45 | 4,323 | BJ62Z18 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $99,074.24 | 4,621 | BLB0YH0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $98,270.40 | 3,540 | BP9N0G0 |
| 0.12% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $96,889.20 | 3,945 | BN7Q7R7 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $96,552.59 | 2,053 | BRXB0C0 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $94,513.72 | 5,948 | BFWLC09 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $93,749.20 | 4,460 | BV2DHY6 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $89,425.08 | 3,348 | BPCQZY9 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $89,092.85 | 2,555 | BJQ05Z6 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $88,629.31 | 2,387 | BMVNDH9 |
| 0.11% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $88,511.17 | 2,621 | BCBVTX1 |
| 0.11% | GRAL | GRAIL INC | -- | $88,509.54 | 1,743 | BSLSSX7 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $83,127.96 | 4,913 | BPCK358 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,002.38 | 9,739 | BNZB1X8 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $81,763.60 | 2,879 | BBC9WC7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $81,269.60 | 1,240 | BDRW1L7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $79,247.03 | 1,003 | BCDWBX6 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,153.11 | 23,349 | BM9FJ13 |
| 0.10% | PHVS | PHARVARIS NV | -- | $78,986.96 | 2,866 | BMZ2X38 |
| 0.09% | INVA | INNOVIVA INC | -- | $78,253.06 | 3,313 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $77,282.13 | 2,271 | BSBMN89 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $74,969.52 | 5,736 | BJH9ZN0 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $73,789.15 | 1,997 | BQKXDX4 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,680.36 | 2,588 | BKSGZN7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $73,289.08 | 5,284 | BYZM6C2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $71,827.08 | 2,132 | BR3T9B6 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $71,760.00 | 4,600 | BMVLGP2 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $69,100.80 | 3,776 | BMX9K07 |
| 0.08% | VIR | VIR BIOTECHNOLOGY INC | -- | $66,935.12 | 7,031 | BK4PZ38 |
| 0.08% | ARDX | ARDELYX INC | -- | $66,917.00 | 10,970 | BN89V40 |
| 0.08% | PGEN | PRECIGEN INC | -- | $65,211.36 | 15,828 | BKM5C84 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $63,945.16 | 18,428 | BF0DMK7 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $63,604.94 | 2,009 | BQXJKH2 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $62,457.85 | 1,961 | BLCD809 |
| 0.07% | NVAX | NOVAVAX INC | -- | $61,364.96 | 7,288 | BJDQXG4 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $61,242.74 | 2,834 | BQB42F1 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $61,092.48 | 16,248 | BWJDYK1 |
| 0.07% | HROW | HARROW INC | -- | $60,898.34 | 1,658 | BHNDW86 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $60,477.77 | 2,153 | BSRK699 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $59,789.10 | 8,421 | BYZG9R0 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,396.32 | 3,411 | BP7KZP7 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $56,248.65 | 3,585 | BMZ4LN0 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,751.15 | 12,253 | BNC1BX1 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $54,966.72 | 3,694 | BYP80F1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $54,921.10 | 5,090 | BYSS4X4 |
| 0.07% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $54,143.18 | 923 | BL95N25 |
| 0.07% | SVRA | SAVARA INC | -- | $54,071.82 | 9,103 | BYXGN81 |
| 0.06% | ALVO | ALVOTECH SA | -- | $52,898.08 | 14,776 | BPNTJ34 |
| 0.06% | EYPT | EYEPOINT INC | -- | $52,485.68 | 3,704 | BMGS7L1 |
| 0.06% | ZBIO | ZENAS BIOPHARMA INC | -- | $50,794.10 | 2,435 | BQB42H3 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,053.47 | 2,003 | BQNKXX2 |
| 0.06% | GERN | GERON CORP | -- | $48,830.76 | 28,556 | 2370381 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $47,504.03 | 1,421 | BX7RSN3 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,636.75 | 1,847 | BMGTLY5 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,517.66 | 13,562 | BL53SR3 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $45,784.23 | 5,457 | B8K7T65 |
| 0.05% | QURE | UNIQURE NV | -- | $44,285.43 | 2,787 | BJFSR88 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,938.24 | 7,422 | BLR7H87 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $43,701.63 | 651 | BNSP8K3 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $43,569.47 | 2,261 | BD06CS0 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,082.50 | 1,810 | B3X26D8 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $41,618.44 | 3,524 | BJLKVS6 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $41,597.25 | 2,775 | BP6C0S2 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $41,391.60 | 2,029 | BNFWZS4 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $40,634.50 | 4,490 | BKVDFF7 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,282.29 | 4,183 | BRXYZ57 |
| 0.05% | XNCR | XENCOR INC | -- | $40,192.25 | 3,281 | BGCYWN8 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $39,976.30 | 2,093 | BZ7PJQ1 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,550.66 | 2,722 | BMFX8Y7 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $39,539.28 | 2,643 | BM90J52 |
| 0.05% | ANNX | ANNEXON INC | -- | $39,173.75 | 6,475 | BMVV9R5 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $38,250.36 | 11,916 | BMFJJ97 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,685.52 | 8,604 | BZ0QMB7 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $37,632.20 | 2,267 | BMNDK09 |
| 0.04% | OMER | OMEROS CORP | -- | $36,498.21 | 3,171 | B4NB858 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,224.37 | 4,423 | BMCR7V2 |
| 0.04% | MNKD | MANNKIND CORP | -- | $35,973.63 | 13,783 | BF081J4 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $35,069.76 | 1,944 | BT9K6D8 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,210.68 | 3,892 | BYZD465 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $33,804.00 | 3,600 | BFYQFJ2 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $33,502.70 | 1,330 | BKLCWZ3 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $32,790.87 | 1,533 | BD9GVY0 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $32,600.64 | 2,342 | BQS7491 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $32,283.16 | 2,548 | BMFK3H6 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $32,210.75 | 7,579 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $32,083.02 | 2,862 | BDZ30Q0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $31,647.61 | 1,199 | BGL0JK3 |
| 0.04% | PSNL | PERSONALIS INC | -- | $29,630.73 | 4,681 | BJQ0608 |
| 0.04% | VOR | VOR BIOPHARMA INC | -- | $29,254.21 | 1,858 | BRJJYT3 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $28,585.50 | 8,075 | BPBJFM7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $27,957.72 | 3,486 | BQHN6C7 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $27,143.10 | 10,053 | BFZNYB7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $25,645.20 | 2,408 | B91XRN2 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $25,559.82 | 7,282 | B3MZ6K5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,478.52 | 3,524 | BJ0LT31 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,250.40 | 840 | BPBPCG8 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $24,917.02 | 10,694 | BBNBTD2 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $24,722.13 | 4,857 | BMXNGZ6 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $24,530.16 | 1,713 | BP81RK8 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $24,170.49 | 813 | BQD3J33 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $24,138.40 | 4,220 | BMC3HS7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,138.03 | 2,517 | BLFBZ32 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $23,793.12 | 2,418 | BRCFFK6 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $23,566.32 | 2,556 | BSMLR16 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $23,534.10 | 2,979 | BJDX8Z9 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $23,048.20 | 2,282 | BKLXFX5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,814.44 | 5,458 | BYVQJ96 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,861.07 | 2,581 | B2Q9833 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $21,787.41 | 951 | BTNMG41 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $21,739.19 | 3,694 | BDDVW37 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,310.25 | 5,395 | BYV2W40 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,026.60 | 3,265 | BQ6C357 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $20,725.35 | 3,495 | BLN9Z50 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,367.39 | 6,549 | BMCWKZ2 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,110.74 | 6,726 | BN94K69 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,858.23 | 13,509 | B4N8MH9 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,628.88 | 2,264 | BZ0G875 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $19,347.66 | 2,654 | B12W3P6 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $19,233.57 | 2,841 | BP81R42 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $19,182.96 | 664 | B292NQ7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $18,878.74 | 5,602 | BFY7DC4 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,887.23 | 1,299 | B9L5200 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $17,488.80 | 4,858 | BDFKQ07 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,419.98 | 1,362 | BPRBTY7 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $17,105.65 | 1,363 | BM7V485 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $17,092.76 | 2,276 | B7F2TY6 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,734.60 | 12,396 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $16,295.50 | 7,475 | BN4JN37 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,186.50 | 3,270 | BP0TQC5 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,785.00 | 2,870 | BMVBZF5 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,954.12 | 692 | BS2F741 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $14,674.32 | 3,204 | 2107437 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $14,448.21 | 4,501 | BZC0D70 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,369.77 | 8,973 | BFMLGR4 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,305.54 | 4,306 | BK5MWR1 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $13,220.55 | 1,399 | BQV0J03 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,811.80 | 2,620 | BMF7DT9 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,655.60 | 4,364 | BKX9NQ0 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,603.84 | 4,146 | BYTYP72 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $12,301.45 | 5,021 | BKRRKY7 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $12,285.00 | 2,100 | BL5B6Z1 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $12,050.16 | 4,366 | BZ8FPH3 |
| 0.01% | EOLS | EVOLUS INC | -- | $11,856.91 | 2,899 | BDRJH21 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,367.90 | 6,687 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,803.50 | 1,271 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,781.75 | 2,525 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,337.04 | 2,637 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,323.54 | 2,073 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $9,787.28 | 6,439 | BN13S71 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,930.61 | 4,041 | B5LL2C2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $8,897.60 | 3,320 | BPTK6Z2 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,152.95 | 4,181 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,747.74 | 1,386 | BP2NYN2 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,102.00 | 1,675 | 2517058 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,031.54 | 9,696 | BNNXX52 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,775.02 | 2,394 | BP7L561 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,560.87 | 8,742 | BNR5QT9 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,372.50 | 2,549 | BKTV702 |
| 0.01% | HUMA | HUMACYTE INC | -- | $5,624.40 | 8,633 | BMYTJP4 |
| 0.01% | PEPG | PEPGEN INC | -- | $5,106.16 | 3,076 | BMTX3D7 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $4,095.42 | 2,786 | BLBR8D5 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $3,823.89 | 973 | BTXQTX3 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,626.09 | 4,363 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,596.98 | 10,354 | BJ0CK86 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $27.05 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 37.25% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 30,876,443 | -- | 5,213 | -- |
| 30.60% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 25,368,081 | -- | 4,283 | -- |
| 26.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,926,835 | -- | 3,702 | -- |
| 18.86% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,630,718 | -- | 2,639 | -- |
| 14.22% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,786,710 | -- | 1,990 | -- |
| 4.52% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,749,240 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $26,758,523.96 | 26,758,524 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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