BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 0.06% | -1.91% | 14.30% | 2.28% | 73.28% | 14.74% | -1.02% | -- | 16.23% | 04/07/2010 |
| BIB Market Price | 0.13% | -1.80% | 14.32% | 2.32% | 73.45% | 14.71% | -1.06% | -- | 16.23% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $68,477,953
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/08/2026- NAV
- NAV Change
- Market Price $78.67
- Market Price Change $-1.60
- Trading Volume (M) 5,094
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $68,477,953
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 6/08/2026- NAV
- NAV Change
- Market Price $78.67
- Market Price Change $-1.60
- Trading Volume (M) 5,094
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 6/08/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.95% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,391,744.72 | 7,657 | 2931034 |
| 4.95% | AMGN | AMGEN INC | -- | $3,389,191.19 | 9,803 | 2023607 |
| 4.78% | GILD | GILEAD SCIENCES INC | -- | $3,271,930.20 | 25,542 | 2369174 |
| 3.43% | REGN | REGENERON PHARMACEUTICALS | -- | $2,347,545.60 | 3,840 | 2730190 |
| 2.09% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,432,752.64 | 4,904 | B00FWN1 |
| 1.59% | RVMD | REVOLUTION MEDICINES INC | -- | $1,087,837.74 | 7,326 | BL71K91 |
| 1.53% | BIIB | BIOGEN INC | -- | $1,044,963.50 | 5,425 | 2455965 |
| 1.35% | ARGX | ARGENX SE - ADR | -- | $926,530.50 | 1,050 | BDVLM39 |
| 1.30% | ILMN | ILLUMINA INC | -- | $893,400.12 | 5,653 | 2613990 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $882,397.80 | 1,620 | 2430412 |
| 1.27% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $868,817.82 | 15,837 | BMVP7Y0 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $753,845.40 | 26,460 | BMW4NZ9 |
| 1.10% | INSM | INSMED INC | -- | $750,346.56 | 7,968 | 2614487 |
| 1.08% | INCY | INCYTE CORP | -- | $740,609.76 | 7,359 | 2471950 |
| 1.01% | MRNA | MODERNA INC | -- | $694,960.00 | 14,600 | BGSXTS3 |
| 0.99% | VTRS | VIATRIS INC | -- | $678,060.45 | 42,565 | BMWS3X9 |
| 0.88% | GH | GUARDANT HEALTH INC | -- | $605,716.50 | 4,850 | BFXC911 |
| 0.88% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $605,501.44 | 3,712 | 2623911 |
| 0.77% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $527,891.00 | 2,275 | B4Q5ZN4 |
| 0.73% | EXEL | EXELIXIS INC | -- | $496,704.00 | 9,600 | 2576941 |
| 0.71% | BBIO | BRIDGEBIO PHARMA INC | -- | $482,840.79 | 7,167 | BK1KWG8 |
| 0.70% | MEDP | MEDPACE HOLDINGS INC | -- | $481,252.90 | 1,051 | BDCBC61 |
| 0.68% | ASND | ASCENDIS PHARMA A/S | -- | $468,423.56 | 2,276 | BWXJHM8 |
| 0.66% | IONS | IONIS PHARMACEUTICALS INC | -- | $449,255.86 | 6,109 | BDJ0LS6 |
| 0.65% | AXSM | AXSOME THERAPEUTICS INC | -- | $444,414.60 | 1,890 | BYZR4X4 |
| 0.59% | SMMT | SUMMIT THERAPEUTICS INC | -- | $404,449.04 | 28,664 | BMTVQS7 |
| 0.59% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $402,070.50 | 7,110 | 2437071 |
| 0.58% | SNY | SANOFI-ADR | -- | $396,982.36 | 9,047 | 2964557 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $395,786.16 | 847 | BD59BS7 |
| 0.56% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $382,447.08 | 5,178 | BYQBFJ8 |
| 0.53% | BNTX | BIONTECH SE-ADR | -- | $360,211.50 | 4,213 | BK6H543 |
| 0.48% | KRYS | KRYSTAL BIOTECH INC | -- | $325,900.80 | 1,080 | BD6JX35 |
| 0.47% | ONC | BEONE MEDICINES LTD-ADR | -- | $319,814.80 | 1,181 | BYYWPW6 |
| 0.46% | TEM | TEMPUS AI INC-CL A | -- | $312,142.16 | 6,424 | BSLSJJ0 |
| 0.45% | CYTK | CYTOKINETICS INC | -- | $309,148.70 | 4,553 | BBBSBJ5 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $308,665.72 | 4,364 | 2975098 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $272,517.36 | 38,008 | BNSP0B8 |
| 0.38% | ALKS | ALKERMES PLC | -- | $261,619.35 | 6,163 | B3P6D26 |
| 0.38% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $260,594.25 | 1,029 | BQ721R4 |
| 0.36% | PCVX | VAXCYTE INC | -- | $246,521.93 | 5,321 | BKPVGH6 |
| 0.35% | NUVL | NUVALENT INC-A | -- | $239,365.45 | 2,705 | BMVBZD3 |
| 0.34% | IMVT | IMMUNOVANT INC | -- | $231,708.40 | 7,523 | BJRFSB7 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $231,448.83 | 2,361 | BDCBCD8 |
| 0.34% | ABVX | ABIVAX SA-ADR | -- | $230,574.63 | 2,271 | BLC89B2 |
| 0.33% | KYMR | KYMERA THERAPEUTICS INC | -- | $223,107.15 | 3,017 | BMPRZV5 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $217,046.55 | 2,526 | BF2YWG4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $217,003.94 | 3,062 | B17VCN9 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $209,160.00 | 2,905 | BQBBDY8 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $208,788.14 | 2,231 | BJDX8Y8 |
| 0.27% | COGT | COGENT BIOSCIENCES INC | -- | $187,022.32 | 6,002 | BLR6XK8 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $183,180.00 | 3,550 | BDHF4K6 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $175,593.10 | 4,423 | BLB0YQ9 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $174,984.00 | 736 | 2501578 |
| 0.25% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $172,891.36 | 4,624 | BTZRLN8 |
| 0.25% | CGON | CG ONCOLOGY INC | -- | $169,891.20 | 3,123 | BRBCSP4 |
| 0.25% | CAI | CARIS LIFE SCIENCES INC | -- | $168,356.34 | 10,431 | BT18HP9 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $168,344.28 | 2,028 | BM9HHL5 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $165,257.40 | 3,773 | BFZQ0L8 |
| 0.23% | TVTX | TRAVERE THERAPEUTICS INC | -- | $160,495.72 | 3,409 | BLFGJD5 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $159,474.72 | 11,632 | BFNF1D6 |
| 0.23% | TWST | TWIST BIOSCIENCE CORP | -- | $158,710.64 | 2,266 | BGKG6G7 |
| 0.23% | XENE | XENON PHARMACEUTICALS INC | -- | $157,419.54 | 3,074 | BRJ3GY4 |
| 0.22% | TNGX | TANGO THERAPEUTICS INC | -- | $153,969.54 | 4,978 | BP2P6L0 |
| 0.22% | ERAS | ERASCA INC | -- | $147,284.28 | 11,444 | BNLYBF3 |
| 0.20% | VCYT | VERACYTE INC | -- | $138,879.26 | 2,938 | BFTWZY0 |
| 0.20% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $138,175.44 | 3,966 | BKY5JZ8 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $136,775.10 | 6,303 | 2713317 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $131,599.40 | 4,252 | BP8JSP4 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $129,634.56 | 3,872 | BDD19F8 |
| 0.19% | TXG | 10X GENOMICS INC-CLASS A | -- | $126,962.18 | 4,351 | BKS3RS7 |
| 0.17% | ORKA | ORUKA THERAPEUTICS INC | -- | $114,603.34 | 1,789 | BKVF0J2 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $114,563.02 | 5,863 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $112,181.26 | 3,767 | BK6L288 |
| 0.16% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $108,777.60 | 2,880 | BQS9486 |
| 0.15% | DYN | DYNE THERAPEUTICS INC | -- | $102,322.47 | 6,087 | BN15WD1 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $102,184.08 | 3,246 | BK0VHF6 |
| 0.14% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $98,803.98 | 4,587 | BKX9VD3 |
| 0.14% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $98,405.44 | 3,122 | BMX9K07 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $95,056.40 | 5,692 | BJ5FZ74 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $94,297.60 | 2,120 | B72ZBG4 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $93,813.72 | 1,573 | BMH5RL1 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $92,843.80 | 1,411 | BMGJZJ8 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $90,237.96 | 6,606 | BN2R582 |
| 0.13% | ALMS | ALUMIS INC | -- | $88,759.26 | 4,674 | BPLQG36 |
| 0.13% | GRAL | GRAIL INC | -- | $88,527.28 | 1,439 | BSLSSX7 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,828.70 | 3,685 | BV2DHY6 |
| 0.12% | VERA | VERA THERAPEUTICS INC | -- | $83,693.00 | 2,636 | BL55460 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $83,269.92 | 1,698 | BRXB0C0 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $78,154.53 | 9,271 | 2100362 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $77,097.89 | 3,571 | BJ62Z18 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $76,953.24 | 4,914 | BFWLC09 |
| 0.11% | PHVS | PHARVARIS NV | -- | $74,773.53 | 2,367 | BMZ2X38 |
| 0.11% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $73,851.48 | 2,196 | BMFD115 |
| 0.10% | ADMA | ADMA BIOLOGICS INC | -- | $70,968.30 | 8,805 | B9NSBM2 |
| 0.10% | NVCR | NOVOCURE LTD | -- | $70,921.65 | 4,209 | BYSS4X4 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $69,314.60 | 2,140 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $67,068.75 | 1,875 | BSBMN89 |
| 0.10% | KOD | KODIAK SCIENCES INC | -- | $66,770.55 | 2,255 | BFXC933 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $66,507.90 | 830 | BCDWBX6 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $66,190.38 | 2,766 | BPCQZY9 |
| 0.10% | MLYS | MINERALYS THERAPEUTICS INC | -- | $65,812.50 | 2,925 | BP9N0G0 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $65,679.84 | 8,049 | BNZB1X8 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $64,703.52 | 1,764 | BR3T9B6 |
| 0.09% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $64,066.04 | 19,297 | BM9FJ13 |
| 0.09% | TRVI | TREVI THERAPEUTICS INC | -- | $64,017.00 | 4,742 | BJH9ZN0 |
| 0.09% | QURE | UNIQURE NV | -- | $62,235.00 | 2,305 | BJFSR88 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $61,219.00 | 2,111 | BJQ05Z6 |
| 0.09% | INVA | INNOVIVA INC | -- | $61,184.20 | 2,740 | BDDXF67 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $60,928.00 | 15,232 | BF0DMK7 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $60,752.78 | 11,209 | BL53SR3 |
| 0.09% | SRPT | SAREPTA THERAPEUTICS INC | -- | $60,256.25 | 3,875 | B8DPDT7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $59,463.28 | 3,802 | BMVLGP2 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $59,435.04 | 2,166 | BCBVTX1 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $58,999.20 | 2,379 | BBC9WC7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $58,937.81 | 4,369 | BYZM6C2 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $57,249.35 | 3,455 | BRXYZ57 |
| 0.08% | SION | SIONNA THERAPEUTICS INC | -- | $55,325.01 | 1,651 | BQKXDX4 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $55,306.56 | 3,261 | BN7Q7R7 |
| 0.08% | TSHA | TAYSHA GENE THERAPIES INC | -- | $54,995.04 | 10,128 | BNC1BX1 |
| 0.08% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $52,807.59 | 4,059 | BPCK358 |
| 0.08% | TYRA | TYRA BIOSCIENCES INC | -- | $52,804.50 | 1,974 | BMVNDH9 |
| 0.08% | ANAB | ANAPTYSBIO INC | -- | $52,541.28 | 1,023 | BDRW1L7 |
| 0.08% | NVAX | NOVAVAX INC | -- | $51,918.26 | 6,023 | BJDQXG4 |
| 0.08% | ALVO | ALVOTECH SA | -- | $51,770.40 | 12,210 | BPNTJ34 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $51,164.49 | 13,429 | BWJDYK1 |
| 0.07% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $50,471.30 | 1,870 | BD06CS0 |
| 0.07% | SEPN | SEPTERNA INC | -- | $50,389.37 | 1,657 | BQNKXX2 |
| 0.07% | ARDX | ARDELYX INC | -- | $50,225.64 | 9,066 | BN89V40 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $49,094.50 | 5,810 | BK4PZ38 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $48,082.00 | 1,658 | BQXJKH2 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $47,906.00 | 2,818 | BP7KZP7 |
| 0.07% | INBX | INHIBRX BIOSCIENCES INC | -- | $47,862.81 | 537 | BNSP8K3 |
| 0.07% | URGN | UROGEN PHARMA LTD | -- | $47,142.50 | 1,730 | BZ7PJQ1 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $47,094.30 | 2,343 | BQB42F1 |
| 0.07% | PGEN | PRECIGEN INC | -- | $46,695.60 | 13,080 | BKM5C84 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $46,573.50 | 1,527 | BMGTLY5 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $46,155.28 | 2,294 | BP6C0S2 |
| 0.07% | HROW | HARROW INC | -- | $45,347.00 | 1,370 | BHNDW86 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,047.59 | 1,621 | BLCD809 |
| 0.06% | MAZE | MAZE THERAPEUTICS INC | -- | $41,925.24 | 1,778 | BSRK699 |
| 0.06% | CMPS | COMPASS PATHWAYS PLC | -- | $40,902.51 | 3,487 | BMC3HS7 |
| 0.06% | WVE | WAVE LIFE SCIENCES LTD | -- | $39,672.00 | 6,960 | BYZG9R0 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $38,992.44 | 1,172 | BX7RSN3 |
| 0.06% | PSNL | PERSONALIS INC | -- | $38,844.76 | 3,869 | BJQ0608 |
| 0.06% | MNKD | MANNKIND CORP | -- | $38,608.71 | 11,389 | BF081J4 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $38,276.16 | 6,134 | BLR7H87 |
| 0.06% | SVRA | SAVARA INC | -- | $38,071.44 | 7,524 | BYXGN81 |
| 0.05% | ABSI | ABSCI CORP | -- | $36,424.55 | 5,561 | BN94K69 |
| 0.05% | EYPT | EYEPOINT INC | -- | $35,059.90 | 3,062 | BMGS7L1 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $34,920.63 | 1,983 | BQB42H3 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $34,175.70 | 1,495 | B3X26D8 |
| 0.05% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $34,052.10 | 3,054 | BYP80F1 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $33,058.30 | 4,510 | B8K7T65 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $32,867.44 | 3,656 | BMCR7V2 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $32,517.03 | 1,677 | BNFWZS4 |
| 0.05% | XNCR | XENCOR INC | -- | $30,932.51 | 2,711 | BGCYWN8 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,543.75 | 1,875 | BMNDK09 |
| 0.04% | JANX | JANUX THERAPEUTICS INC | -- | $30,411.01 | 2,251 | BMFX8Y7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $30,146.40 | 7,110 | BZ0QMB7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $29,710.40 | 992 | BGL0JK3 |
| 0.04% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $29,501.52 | 2,962 | BMZ4LN0 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $29,120.00 | 2,912 | BJLKVS6 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $29,016.80 | 2,185 | BM90J52 |
| 0.04% | ORIC | ORIC PHARMACEUTICALS INC | -- | $27,943.83 | 3,711 | BKVDFF7 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $27,836.55 | 8,837 | BBNBTD2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $27,546.08 | 3,218 | BYZD465 |
| 0.04% | ANNX | ANNEXON INC | -- | $27,386.88 | 5,349 | BMVV9R5 |
| 0.04% | REPL | REPLIMUNE GROUP INC | -- | $27,385.41 | 3,053 | BDDVW37 |
| 0.04% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $27,266.40 | 5,410 | BMCWKZ2 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $27,042.75 | 2,975 | BFYQFJ2 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $26,689.20 | 1,934 | BQS7491 |
| 0.04% | GERN | GERON CORP | -- | $26,670.26 | 23,602 | 2370381 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $26,493.81 | 9,849 | BMFJJ97 |
| 0.04% | OMER | OMEROS CORP | -- | $25,826.70 | 2,622 | B4NB858 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $25,183.47 | 2,083 | BLFBZ32 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $24,878.04 | 1,604 | BT9K6D8 |
| 0.04% | CRMD | CORMEDIX INC | -- | $24,859.94 | 2,911 | BJ0LT31 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $24,232.88 | 763 | BL95N25 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $23,009.50 | 2,707 | BP0TQC5 |
| 0.03% | CSTL | CASTLE BIOSCIENCES INC | -- | $22,132.00 | 1,100 | BKLCWZ3 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $22,018.30 | 2,105 | BMFK3H6 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $20,913.12 | 1,269 | BD9GVY0 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $20,413.44 | 1,536 | BRJJYT3 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,213.76 | 672 | BQD3J33 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,166.30 | 693 | BPBPCG8 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $19,832.12 | 6,028 | B3MZ6K5 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $19,752.08 | 6,673 | BPBJFM7 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,441.24 | 4,459 | BYV2W40 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $18,460.80 | 2,880 | BQHN6C7 |
| 0.03% | CTMX | CYTOMX THERAPEUTICS INC | -- | $18,419.10 | 6,265 | BYWVTY5 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,638.01 | 4,511 | BYVQJ96 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $17,025.84 | 1,989 | B91XRN2 |
| 0.02% | ARVN | ARVINAS INC | -- | $16,895.45 | 2,363 | BDZ30Q0 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,330.60 | 571 | BS2F741 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $16,286.40 | 1,885 | BKLXFX5 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $16,283.52 | 2,112 | BSMLR16 |
| 0.02% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $16,112.25 | 1,023 | BS2CR64 |
| 0.02% | EOLS | EVOLUS INC | -- | $16,011.96 | 2,397 | BDRJH21 |
| 0.02% | KMDA | KAMADA LTD | -- | $15,450.16 | 2,134 | B2Q9833 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $15,404.94 | 11,163 | B4N8MH9 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $15,369.80 | 8,308 | BFZNYB7 |
| 0.02% | LKFT | LAKEFRONT BIOTHERAPEUTIC-ADR | -- | $15,250.84 | 548 | B292NQ7 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $15,221.52 | 2,349 | BP81R42 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $12,984.84 | 2,186 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $12,959.72 | 1,124 | BPRBTY7 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,956.31 | 3,609 | BKX9NQ0 |
| 0.02% | UPB | UPSTREAM BIO INC | -- | $12,880.65 | 1,997 | BRCFFK6 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $12,871.15 | 1,879 | B7F2TY6 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $12,642.63 | 4,631 | BFY7DC4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $12,480.48 | 2,889 | BLN9Z50 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $12,443.40 | 4,014 | BMXNGZ6 |
| 0.02% | OABI | OMNIAB INC | -- | $12,134.16 | 5,322 | BN13S71 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $11,867.04 | 1,072 | B9L5200 |
| 0.02% | RGNX | REGENXBIO INC | -- | $11,481.49 | 1,873 | BZ0G875 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $11,457.18 | 2,646 | 2107437 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $11,382.40 | 3,557 | BK5MWR1 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $11,354.37 | 2,697 | BQ6C357 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $11,250.00 | 1,125 | BM7V485 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,835.10 | 4,013 | BDFKQ07 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,824.44 | 7,414 | BFMLGR4 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $10,815.28 | 1,736 | BL5B6Z1 |
| 0.02% | IVVD | INVIVYD INC | -- | $10,448.88 | 10,244 | BM8NHS1 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $10,005.12 | 6,176 | BN4JN37 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,847.68 | 7,136 | BMYTJP4 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $9,687.97 | 787 | BTNMG41 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,551.10 | 3,611 | BZ8FPH3 |
| 0.01% | IMRX | IMMUNEERING CORP - CLASS A | -- | $9,380.91 | 2,387 | BMVBZF5 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $9,211.65 | 1,981 | BP7L561 |
| 0.01% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $8,976.12 | 3,426 | BYTYP72 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $8,864.16 | 1,416 | BP81RK8 |
| 0.01% | CDXS | CODEXIS INC | -- | $8,703.31 | 3,341 | B5LL2C2 |
| 0.01% | FULC | FULCRUM THERAPEUTICS INC | -- | $8,476.16 | 2,464 | BJDX8Z9 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,251.55 | 2,089 | BPRB2N7 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,148.99 | 3,721 | BZC0D70 |
| 0.01% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,032.15 | 2,165 | BMF7DT9 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $7,845.50 | 5,525 | BRK0149 |
| 0.01% | LENZ | LENZ THERAPEUTICS INC | -- | $7,781.76 | 1,158 | BQV0J03 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,725.59 | 1,387 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,663.80 | 7,230 | BNR5QT9 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $7,490.24 | 1,052 | BKC9SX3 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,489.91 | 1,147 | BP2NYN2 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,343.23 | 2,179 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $7,032.21 | 1,711 | BKDQKM6 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $6,475.56 | 4,151 | BKRRKY7 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,355.36 | 3,454 | BNYJR68 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,499.44 | 8,012 | BNNXX52 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,486.00 | 2,743 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $3,894.25 | 2,105 | BKTV702 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $3,892.07 | 2,303 | BLBR8D5 |
| 0.01% | PEPG | PEPGEN INC | -- | $3,430.35 | 2,541 | BMTX3D7 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,029.28 | 3,608 | BNNXX18 |
| -- | AARD | AARDVARK THERAPEUTICS INC | -- | $2,886.36 | 804 | BTXQTX3 |
| -- | GOSS | GOSSAMER BIO INC | -- | $1,416.71 | 8,555 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 29.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,390,992 | -- | 3,524 | -- |
| 29.63% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 20,292,624 | -- | 3,507 | -- |
| 25.98% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 17,792,934 | -- | 3,075 | -- |
| 22.30% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,270,098 | -- | 2,639 | -- |
| 21.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,541,022 | -- | 2,513 | -- |
| 5.35% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,662,741 | -- | 633 | -- |
| -- | IQMM | PROSHARES GENIUS MNY MKT ETF | -- | $5,006,500.00 | 50,000 | BTGTPK8 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $18,618,639.59 | 18,618,640 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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