BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,892,922
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/20/2026- NAV $75.14
- NAV Change $-2.63
- Market Price $75.08
- Market Price Change $-2.68
- Trading Volume (M) 14,497
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,892,922
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/20/2026- NAV $75.14
- NAV Change $-2.63
- Market Price $75.08
- Market Price Change $-2.68
- Trading Volume (M) 14,497
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/20/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.75% | GILD | GILEAD SCIENCES INC | -- | $4,360,122.17 | 31,777 | 2369174 |
| 5.70% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $4,325,258.00 | 9,527 | 2931034 |
| 5.59% | AMGN | AMGEN INC | -- | $4,241,073.20 | 12,194 | 2023607 |
| 4.62% | REGN | REGENERON PHARMACEUTICALS | -- | $3,502,385.73 | 4,779 | 2730190 |
| 2.51% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,904,237.00 | 6,100 | B00FWN1 |
| 1.78% | INSM | INSMED INC | -- | $1,348,304.00 | 9,914 | 2614487 |
| 1.61% | BIIB | BIOGEN INC | -- | $1,224,855.00 | 6,750 | 2455965 |
| 1.39% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,056,948.48 | 2,016 | 2430412 |
| 1.23% | MRNA | MODERNA INC | -- | $933,317.70 | 18,165 | BGSXTS3 |
| 1.20% | ROIV | ROIVANT SCIENCES LTD | -- | $911,856.30 | 32,919 | BMW4NZ9 |
| 1.18% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $893,818.80 | 19,705 | BMVP7Y0 |
| 1.15% | ILMN | ILLUMINA INC | -- | $874,412.89 | 7,033 | 2613990 |
| 1.15% | RVMD | REVOLUTION MEDICINES INC | -- | $873,034.70 | 9,115 | BL71K91 |
| 1.14% | ARGX | ARGENX SE - ADR | -- | $866,428.65 | 1,305 | BDVLM39 |
| 1.10% | INCY | INCYTE CORP | -- | $831,000.12 | 9,154 | 2471950 |
| 0.92% | VTRS | VIATRIS INC | -- | $699,058.80 | 52,959 | BMWS3X9 |
| 0.83% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $628,364.16 | 2,832 | BV9G6B8 |
| 0.81% | BBIO | BRIDGEBIO PHARMA INC | -- | $611,171.18 | 8,917 | BK1KWG8 |
| 0.78% | MEDP | MEDPACE HOLDINGS INC | -- | $590,525.55 | 1,305 | BDCBC61 |
| 0.78% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $589,370.88 | 4,616 | 2623911 |
| 0.73% | SMMT | SUMMIT THERAPEUTICS INC | -- | $553,148.64 | 35,664 | BMTVQS7 |
| 0.71% | IONS | IONIS PHARMACEUTICALS INC | -- | $539,382.02 | 7,598 | BDJ0LS6 |
| 0.68% | GH | GUARDANT HEALTH INC | -- | $513,890.94 | 6,033 | BFXC911 |
| 0.67% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $511,515.84 | 2,832 | B4Q5ZN4 |
| 0.66% | SNY | SANOFI-ADR | -- | $502,062.20 | 11,257 | 2964557 |
| 0.65% | EXEL | EXELIXIS INC | -- | $492,970.15 | 11,945 | 2576941 |
| 0.63% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $478,833.98 | 8,846 | 2437071 |
| 0.62% | BNTX | BIONTECH SE-ADR | -- | $467,774.80 | 5,240 | BK6H543 |
| 0.61% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $465,423.80 | 1,055 | BD59BS7 |
| 0.53% | ONC | BEONE MEDICINES LTD-ADR | -- | $404,661.60 | 1,470 | BYYWPW6 |
| 0.53% | IBRX | IMMUNITYBIO INC | -- | $400,537.83 | 47,289 | BNSP0B8 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $382,135.11 | 1,281 | BQ721R4 |
| 0.49% | TEM | TEMPUS AI INC-CL A | -- | $375,257.36 | 7,991 | BSLSJJ0 |
| 0.49% | AXSM | AXSOME THERAPEUTICS INC | -- | $369,232.76 | 2,353 | BYZR4X4 |
| 0.48% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $362,821.53 | 6,441 | BYQBFJ8 |
| 0.48% | PCVX | VAXCYTE INC | -- | $362,246.40 | 6,620 | BKPVGH6 |
| 0.46% | CYTK | CYTOKINETICS INC | -- | $349,530.50 | 5,665 | BBBSBJ5 |
| 0.45% | HALO | HALOZYME THERAPEUTICS INC | -- | $344,298.04 | 5,428 | 2975098 |
| 0.45% | ABVX | ABIVAX SA-ADR | -- | $340,080.84 | 2,826 | BLC89B2 |
| 0.45% | KRYS | KRYSTAL BIOTECH INC | -- | $338,509.60 | 1,345 | BD6JX35 |
| 0.42% | NUVL | NUVALENT INC-A | -- | $318,995.82 | 3,366 | BMVBZD3 |
| 0.41% | ACLX | ARCELLX INC | -- | $308,731.30 | 2,690 | BPCJ1Q2 |
| 0.39% | KYMR | KYMERA THERAPEUTICS INC | -- | $292,552.05 | 3,755 | BMPRZV5 |
| 0.38% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $290,183.45 | 2,935 | BDCBCD8 |
| 0.36% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $274,680.45 | 3,141 | BF2YWG4 |
| 0.33% | CGON | CG ONCOLOGY INC | -- | $252,770.72 | 3,884 | BRBCSP4 |
| 0.33% | COGT | COGENT BIOSCIENCES INC | -- | $249,181.70 | 7,465 | BLR6XK8 |
| 0.33% | PTCT | PTC THERAPEUTICS INC | -- | $248,597.10 | 3,807 | B17VCN9 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $245,615.25 | 2,775 | BJDX8Y8 |
| 0.31% | CAI | CARIS LIFE SCIENCES INC | -- | $238,924.98 | 12,978 | BT18HP9 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $236,920.04 | 4,891 | BMDJ0C9 |
| 0.28% | ALKS | ALKERMES PLC | -- | $215,769.75 | 7,665 | B3P6D26 |
| 0.28% | IMVT | IMMUNOVANT INC | -- | $215,138.76 | 9,362 | BJRFSB7 |
| 0.28% | XENE | XENON PHARMACEUTICALS INC | -- | $210,200.44 | 3,826 | BRJ3GY4 |
| 0.28% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $209,450.88 | 4,692 | BFZQ0L8 |
| 0.27% | ERAS | ERASCA INC | -- | $207,904.00 | 14,240 | BNLYBF3 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $204,149.60 | 4,415 | BDHF4K6 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $187,810.77 | 917 | 2501578 |
| 0.23% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $174,097.97 | 3,583 | BQS9486 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $171,305.12 | 4,816 | BDD19F8 |
| 0.23% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $171,203.76 | 14,472 | BFNF1D6 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $168,533.60 | 5,752 | BTZRLN8 |
| 0.22% | APGE | APOGEE THERAPEUTICS INC | -- | $166,552.88 | 2,522 | BM9HHL5 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $162,643.08 | 7,842 | 2713317 |
| 0.21% | ADMA | ADMA BIOLOGICS INC | -- | $156,861.28 | 10,954 | B9NSBM2 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $153,034.72 | 5,288 | BP8JSP4 |
| 0.20% | SYRE | SPYRE THERAPEUTICS INC | -- | $149,036.25 | 3,613 | BQBBDY8 |
| 0.20% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $148,857.06 | 5,501 | BLB0YQ9 |
| 0.19% | DNLI | DENALI THERAPEUTICS INC | -- | $147,140.15 | 7,295 | BD2B4V0 |
| 0.19% | ALMS | ALUMIS INC | -- | $145,723.90 | 5,815 | BPLQG36 |
| 0.19% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $143,382.04 | 4,934 | BKY5JZ8 |
| 0.18% | VERA | VERA THERAPEUTICS INC | -- | $133,019.46 | 3,282 | BL55460 |
| 0.18% | DYN | DYNE THERAPEUTICS INC | -- | $132,981.88 | 7,573 | BN15WD1 |
| 0.17% | IDYA | IDEAYA BIOSCIENCES INC | -- | $132,277.25 | 4,039 | BK0VHF6 |
| 0.17% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $126,597.00 | 5,700 | BKX9VD3 |
| 0.17% | TARS | TARSUS PHARMACEUTICALS INC | -- | $126,246.07 | 1,957 | BMH5RL1 |
| 0.17% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $125,943.12 | 2,637 | B72ZBG4 |
| 0.16% | TNGX | TANGO THERAPEUTICS INC | -- | $120,306.90 | 6,195 | BP2P6L0 |
| 0.16% | TWST | TWIST BIOSCIENCE CORP | -- | $118,637.40 | 2,820 | BGKG6G7 |
| 0.15% | VCYT | VERACYTE INC | -- | $116,375.20 | 3,655 | BFTWZY0 |
| 0.15% | BEAM | BEAM THERAPEUTICS INC | -- | $115,391.55 | 4,685 | BK6L288 |
| 0.15% | TVTX | TRAVERE THERAPEUTICS INC | -- | $113,882.12 | 4,243 | BLFGJD5 |
| 0.15% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $111,899.20 | 11,536 | 2100362 |
| 0.14% | MAZE | MAZE THERAPEUTICS INC | -- | $106,290.39 | 2,213 | BSRK699 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $102,088.35 | 1,755 | BMGJZJ8 |
| 0.13% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $101,861.44 | 4,751 | BLB0YH0 |
| 0.13% | WVE | WAVE LIFE SCIENCES LTD | -- | $101,829.84 | 8,659 | BYZG9R0 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $101,194.80 | 5,880 | BYTQ6X1 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $99,526.68 | 5,412 | BKS3RS7 |
| 0.13% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $98,301.11 | 4,057 | BN7Q7R7 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $97,274.88 | 2,111 | BRXB0C0 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $96,173.56 | 7,082 | BJ5FZ74 |
| 0.12% | TYRA | TYRA BIOSCIENCES INC | -- | $91,203.25 | 2,455 | BMVNDH9 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $88,322.15 | 4,445 | BJ62Z18 |
| 0.12% | STOK | STOKE THERAPEUTICS INC | -- | $88,030.77 | 2,627 | BJQ05Z6 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $87,614.80 | 3,640 | BP9N0G0 |
| 0.11% | ORKA | ORUKA THERAPEUTICS INC | -- | $86,652.57 | 2,227 | BKVF0J2 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $85,746.32 | 6,116 | BFWLC09 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $84,382.40 | 4,586 | BV2DHY6 |
| 0.11% | GRAL | GRAIL INC | -- | $83,984.12 | 1,793 | BSLSSX7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,906.34 | 10,013 | BNZB1X8 |
| 0.11% | RLAY | RELAY THERAPEUTICS INC | -- | $81,470.11 | 8,221 | BN2R582 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $80,445.80 | 4,820 | B8DPDT7 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $80,267.44 | 3,442 | BPCQZY9 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $79,453.01 | 1,274 | BDRW1L7 |
| 0.10% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $79,251.90 | 2,730 | BMFD115 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $78,022.75 | 24,007 | BM9FJ13 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $76,984.77 | 1,031 | BCDWBX6 |
| 0.10% | PHVS | PHARVARIS NV | -- | $76,596.00 | 2,946 | BMZ2X38 |
| 0.10% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $75,082.70 | 2,695 | BCBVTX1 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $74,708.67 | 2,053 | BQKXDX4 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $74,321.10 | 2,961 | BBC9WC7 |
| 0.10% | INVA | INNOVIVA INC | -- | $73,931.90 | 3,407 | BDDXF67 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,735.20 | 2,660 | BKSGZN7 |
| 0.10% | VCEL | VERICEL CORP | -- | $73,342.35 | 2,335 | BSBMN89 |
| 0.09% | NVAX | NOVAVAX INC | -- | $72,092.28 | 7,494 | BJDQXG4 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $69,918.12 | 18,948 | BF0DMK7 |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $69,772.56 | 5,434 | BYZM6C2 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $69,754.31 | 5,051 | BPCK358 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $68,253.90 | 4,730 | BMVLGP2 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $67,585.62 | 3,882 | BMX9K07 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $65,783.90 | 7,229 | BK4PZ38 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $62,577.78 | 5,898 | BJH9ZN0 |
| 0.08% | KOD | KODIAK SCIENCES INC | -- | $62,478.00 | 2,808 | BFXC933 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $61,813.54 | 5,234 | BYSS4X4 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $60,328.47 | 2,017 | BLCD809 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,896.80 | 11,280 | BN89V40 |
| 0.08% | RAPP | RAPPORT THERAPEUTICS INC | -- | $59,359.36 | 2,192 | BR3T9B6 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $59,224.20 | 2,065 | BQXJKH2 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $58,303.94 | 16,706 | BWJDYK1 |
| 0.07% | HROW | HARROW INC | -- | $56,709.12 | 1,704 | BHNDW86 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $55,435.60 | 12,599 | BNC1BX1 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $55,058.70 | 2,469 | BQB42H3 |
| 0.07% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $54,814.41 | 3,507 | BP7KZP7 |
| 0.07% | BCAX | BICARA THERAPEUTICS INC | -- | $53,646.74 | 2,914 | BQB42F1 |
| 0.07% | ALVO | ALVOTECH SA | -- | $53,627.76 | 15,192 | BPNTJ34 |
| 0.07% | PGEN | PRECIGEN INC | -- | $53,378.72 | 16,274 | BKM5C84 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $51,912.96 | 3,687 | BMZ4LN0 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $51,777.84 | 1,461 | BX7RSN3 |
| 0.07% | ORIC | ORIC PHARMACEUTICALS INC | -- | $51,514.56 | 4,616 | BKVDFF7 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $50,627.34 | 3,798 | BYP80F1 |
| 0.07% | EYPT | EYEPOINT INC | -- | $50,379.84 | 3,808 | BMGS7L1 |
| 0.07% | SEPN | SEPTERNA INC | -- | $49,786.62 | 2,059 | BQNKXX2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $48,171.24 | 949 | BL95N25 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,409.60 | 13,944 | BL53SR3 |
| 0.06% | SVRA | SAVARA INC | -- | $46,420.64 | 9,359 | BYXGN81 |
| 0.06% | QURE | UNIQURE NV | -- | $46,097.85 | 2,865 | BJFSR88 |
| 0.06% | GERN | GERON CORP | -- | $42,868.52 | 29,362 | 2370381 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $42,531.38 | 5,611 | B8K7T65 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $41,815.98 | 1,899 | BMGTLY5 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,518.08 | 7,632 | BLR7H87 |
| 0.05% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,168.82 | 1,862 | B3X26D8 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,988.53 | 4,301 | BRXYZ57 |
| 0.05% | XNCR | XENCOR INC | -- | $40,914.49 | 3,373 | BGCYWN8 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $40,755.48 | 669 | BNSP8K3 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,696.50 | 2,087 | BNFWZS4 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $40,625.04 | 3,624 | BJLKVS6 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $39,856.41 | 2,853 | BP6C0S2 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,525.00 | 2,325 | BD06CS0 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $39,339.88 | 2,798 | BMFX8Y7 |
| 0.05% | BIOA | BIOAGE LABS INC | -- | $38,561.40 | 1,998 | BT9K6D8 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $38,103.72 | 12,252 | BMFJJ97 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $37,935.86 | 2,153 | BZ7PJQ1 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,507.04 | 8,846 | BZ0QMB7 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $37,148.99 | 4,547 | BMCR7V2 |
| 0.05% | OMER | OMEROS CORP | -- | $35,871.00 | 3,261 | B4NB858 |
| 0.05% | MNKD | MANNKIND CORP | -- | $35,002.37 | 14,171 | BF081J4 |
| 0.05% | PSNL | PERSONALIS INC | -- | $34,942.38 | 4,813 | BJQ0608 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $34,678.85 | 7,793 | BYWVTY5 |
| 0.05% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,614.58 | 2,717 | BM90J52 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $34,578.88 | 2,408 | BQS7491 |
| 0.05% | CSTL | CASTLE BIOSCIENCES INC | -- | $34,200.00 | 1,368 | BKLCWZ3 |
| 0.04% | ANNX | ANNEXON INC | -- | $34,017.27 | 6,657 | BMVV9R5 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $33,403.23 | 2,331 | BMNDK09 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,056.52 | 4,002 | BYZD465 |
| 0.04% | ARVN | ARVINAS INC | -- | $32,185.48 | 2,942 | BDZ30Q0 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,226.56 | 8,303 | BPBJFM7 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $28,527.93 | 1,577 | BD9GVY0 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $28,039.80 | 10,996 | BBNBTD2 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $27,520.56 | 1,233 | BGL0JK3 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $27,012.20 | 2,620 | BMFK3H6 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $26,654.40 | 3,702 | BFYQFJ2 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $26,510.04 | 3,798 | BDDVW37 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $25,816.32 | 864 | BPBPCG8 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,195.52 | 3,584 | BQHN6C7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,896.47 | 2,589 | BLFBZ32 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $23,468.58 | 4,338 | BMC3HS7 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $22,996.40 | 1,910 | BRJJYT3 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $22,763.52 | 7,488 | B3MZ6K5 |
| 0.03% | CRMD | CORMEDIX INC | -- | $22,650.00 | 3,624 | BJ0LT31 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $22,427.55 | 4,995 | BMXNGZ6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $22,335.76 | 5,612 | BYVQJ96 |
| 0.03% | KMDA | KAMADA LTD | -- | $21,899.45 | 2,653 | B2Q9833 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $21,830.82 | 682 | B292NQ7 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,676.60 | 835 | BQD3J33 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $21,665.00 | 2,476 | B91XRN2 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $21,553.62 | 2,486 | BRCFFK6 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $21,397.59 | 10,337 | BFZNYB7 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,866.32 | 2,628 | BSMLR16 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $20,736.51 | 3,063 | BJDX8Z9 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $20,675.16 | 4,994 | BDFKQ07 |
| 0.03% | ABSI | ABSCI CORP | -- | $20,471.36 | 6,916 | BN94K69 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,468.43 | 5,547 | BYV2W40 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $20,336.38 | 3,593 | BLN9Z50 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $20,199.06 | 2,346 | BKLXFX5 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,064.34 | 6,733 | BMCWKZ2 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,916.91 | 1,761 | BP81RK8 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $19,423.36 | 2,728 | B12W3P6 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $19,289.35 | 7,685 | BN4JN37 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $19,238.40 | 5,760 | BFY7DC4 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $19,132.55 | 2,921 | BP81R42 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $18,967.05 | 3,357 | BQ6C357 |
| 0.02% | RGNX | REGENXBIO INC | -- | $18,856.80 | 2,328 | BZ0G875 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,680.24 | 977 | BTNMG41 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,475.03 | 13,891 | B4N8MH9 |
| 0.02% | IVVD | INVIVYD INC | -- | $17,589.48 | 12,746 | BM8NHS1 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $17,303.72 | 4,262 | BYTYP72 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $17,094.00 | 1,400 | BPRBTY7 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $16,709.14 | 3,362 | BP0TQC5 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,700.85 | 1,335 | B9L5200 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,272.36 | 3,294 | 2107437 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $15,354.96 | 1,401 | BM7V485 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $15,080.72 | 1,439 | BQV0J03 |
| 0.02% | PEPG | PEPGEN INC | -- | $14,861.40 | 3,162 | BMTX3D7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,819.04 | 2,952 | BMVBZF5 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $14,320.80 | 2,340 | B7F2TY6 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,831.84 | 2,981 | BDRJH21 |
| 0.02% | NGNE | NEUROGENE INC | -- | $13,563.60 | 712 | BS2F741 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $13,470.00 | 2,694 | BMF7DT9 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,327.20 | 2,160 | BL5B6Z1 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $13,217.28 | 5,163 | BKRRKY7 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,186.95 | 4,627 | BZC0D70 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,018.32 | 4,428 | BK5MWR1 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,640.99 | 9,227 | BFMLGR4 |
| 0.02% | CCCC | C4 THERAPEUTICS INC | -- | $12,117.60 | 4,488 | BKX9NQ0 |
| 0.02% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $12,050.08 | 2,597 | BPRB2N7 |
| 0.02% | OABI | OMNIAB INC | -- | $11,586.75 | 6,621 | BN13S71 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,506.60 | 4,490 | BZ8FPH3 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,450.00 | 6,875 | BRK0149 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,423.80 | 2,711 | BY7RB53 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,269.85 | 2,131 | BKDQKM6 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,665.41 | 1,307 | BKC9SX3 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,039.13 | 4,299 | BNYJR68 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,595.76 | 8,988 | BNR5QT9 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $7,489.46 | 9,970 | BNNXX52 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,949.80 | 8,877 | BMYTJP4 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $6,926.46 | 1,723 | 2517058 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $6,873.32 | 1,426 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,868.98 | 2,462 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,648.00 | 4,155 | B5LL2C2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $5,803.80 | 3,414 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,530.31 | 2,621 | BKTV702 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,070.31 | 4,487 | BNNXX18 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,496.87 | 10,646 | BJ0CK86 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,210.08 | 2,864 | BLBR8D5 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,074.07 | 1,001 | BTXQTX3 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $20.68 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 31.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 23,950,879 | -- | 4,283 | -- |
| 29.67% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 22,513,714 | -- | 4,026 | -- |
| 27.28% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,701,880 | -- | 3,702 | -- |
| 19.45% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 14,757,499 | -- | 2,639 | -- |
| 14.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 11,128,239 | -- | 1,990 | -- |
| 4.66% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,539,787 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $21,101,397.48 | 21,101,397 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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