BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,101,627
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/29/2026- NAV
- NAV Change
- Market Price $78.54
- Market Price Change $-2.09
- Trading Volume (M) 16,379
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $73,101,627
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/29/2026- NAV
- NAV Change
- Market Price $78.54
- Market Price Change $-2.09
- Trading Volume (M) 16,379
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/29/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.99% | AMGN | AMGEN INC | -- | $3,647,573.82 | 10,791 | 2023607 |
| 4.96% | GILD | GILEAD SCIENCES INC | -- | $3,623,109.64 | 28,121 | 2369174 |
| 4.88% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,567,489.96 | 8,429 | 2931034 |
| 3.97% | REGN | REGENERON PHARMACEUTICALS | -- | $2,901,243.72 | 4,227 | 2730190 |
| 2.22% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,625,221.24 | 5,396 | B00FWN1 |
| 1.62% | INSM | INSMED INC | -- | $1,184,618.19 | 8,773 | 2614487 |
| 1.59% | BIIB | BIOGEN INC | -- | $1,160,642.98 | 5,971 | 2455965 |
| 1.55% | RVMD | REVOLUTION MEDICINES INC | -- | $1,133,535.75 | 8,065 | BL71K91 |
| 1.39% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,018,217.81 | 1,783 | 2430412 |
| 1.23% | ARGX | ARGENX SE - ADR | -- | $896,303.10 | 1,155 | BDVLM39 |
| 1.18% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $862,907.64 | 17,436 | BMVP7Y0 |
| 1.10% | INCY | INCYTE CORP | -- | $802,908.20 | 8,102 | 2471950 |
| 1.10% | ROIV | ROIVANT SCIENCES LTD | -- | $801,767.68 | 29,134 | BMW4NZ9 |
| 1.02% | ILMN | ILLUMINA INC | -- | $749,182.88 | 6,224 | 2613990 |
| 1.01% | MRNA | MODERNA INC | -- | $734,857.56 | 16,073 | BGSXTS3 |
| 0.96% | VTRS | VIATRIS INC | -- | $701,569.05 | 46,865 | BMWS3X9 |
| 0.90% | SMMT | SUMMIT THERAPEUTICS INC | -- | $657,394.80 | 31,560 | BMTVQS7 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $559,787.54 | 7,891 | BK1KWG8 |
| 0.75% | ASND | ASCENDIS PHARMA A/S | -- | $551,801.40 | 2,505 | BWXJHM8 |
| 0.73% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $536,205.78 | 4,086 | 2623911 |
| 0.69% | IONS | IONIS PHARMACEUTICALS INC | -- | $503,231.75 | 6,725 | BDJ0LS6 |
| 0.69% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $500,799.60 | 2,505 | B4Q5ZN4 |
| 0.66% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $484,353.72 | 934 | BD59BS7 |
| 0.65% | MEDP | MEDPACE HOLDINGS INC | -- | $477,696.45 | 1,155 | BDCBC61 |
| 0.65% | EXEL | EXELIXIS INC | -- | $472,417.99 | 10,571 | 2576941 |
| 0.64% | BNTX | BIONTECH SE-ADR | -- | $470,980.09 | 4,637 | BK6H543 |
| 0.63% | SNY | SANOFI-ADR | -- | $458,458.80 | 9,960 | 2964557 |
| 0.61% | GH | GUARDANT HEALTH INC | -- | $445,159.17 | 5,337 | BFXC911 |
| 0.58% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $424,355.88 | 7,828 | 2437071 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $402,162.06 | 5,702 | BYQBFJ8 |
| 0.52% | AXSM | AXSOME THERAPEUTICS INC | -- | $382,983.90 | 2,082 | BYZR4X4 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $378,330.80 | 1,301 | BYYWPW6 |
| 0.50% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $366,497.46 | 1,134 | BQ721R4 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $353,641.40 | 7,070 | BSLSJJ0 |
| 0.46% | PCVX | VAXCYTE INC | -- | $335,723.24 | 5,857 | BKPVGH6 |
| 0.42% | KRYS | KRYSTAL BIOTECH INC | -- | $309,860.40 | 1,192 | BD6JX35 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $302,940.24 | 4,804 | 2975098 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $298,734.12 | 5,014 | BBBSBJ5 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $295,318.00 | 2,980 | BMVBZD3 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $291,269.04 | 41,849 | BNSP0B8 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $270,694.71 | 3,321 | BMPRZV5 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $265,493.76 | 2,499 | BLC89B2 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $255,954.96 | 2,598 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $237,028.96 | 6,608 | BLR6XK8 |
| 0.32% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $231,355.20 | 2,456 | BJDX8Y8 |
| 0.31% | SYRE | SPYRE THERAPEUTICS INC | -- | $229,760.44 | 3,196 | BQBBDY8 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $229,090.68 | 4,329 | BMDJ0C9 |
| 0.31% | ALKS | ALKERMES PLC | -- | $228,688.64 | 6,784 | B3P6D26 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $228,293.60 | 2,780 | BF2YWG4 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $223,334.65 | 8,287 | BJRFSB7 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $222,545.75 | 3,437 | BRBCSP4 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $217,404.40 | 3,368 | B17VCN9 |
| 0.29% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,062.85 | 5,203 | BYTQ6X1 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $204,106.22 | 11,486 | BT18HP9 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $198,123.97 | 3,907 | BDHF4K6 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $192,330.20 | 4,154 | BFZQ0L8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,082.05 | 4,869 | BLB0YQ9 |
| 0.26% | XENE | XENON PHARMACEUTICALS INC | -- | $188,769.50 | 3,386 | BRJ3GY4 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $183,008.93 | 2,231 | BM9HHL5 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $182,136.60 | 810 | 2501578 |
| 0.24% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $173,755.20 | 5,088 | BTZRLN8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $163,916.80 | 12,806 | BFNF1D6 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $163,831.28 | 4,262 | BDD19F8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $154,001.40 | 6,937 | 2713317 |
| 0.21% | TVTX | TRAVERE THERAPEUTICS INC | -- | $150,575.50 | 3,755 | BLFGJD5 |
| 0.19% | TWST | TWIST BIOSCIENCE CORP | -- | $141,523.20 | 2,496 | BGKG6G7 |
| 0.18% | ORKA | ORUKA THERAPEUTICS INC | -- | $134,157.00 | 1,970 | BKVF0J2 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $132,995.54 | 4,678 | BP8JSP4 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $132,944.70 | 4,366 | BKY5JZ8 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $131,251.15 | 3,173 | BQS9486 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $121,838.86 | 4,147 | BK6L288 |
| 0.17% | TNGX | TANGO THERAPEUTICS INC | -- | $120,932.92 | 5,482 | BP2P6L0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $120,044.40 | 6,454 | BD2B4V0 |
| 0.16% | ALMS | ALUMIS INC | -- | $117,791.94 | 5,146 | BPLQG36 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $116,647.00 | 6,700 | BN15WD1 |
| 0.16% | ERAS | ERASCA INC | -- | $114,813.33 | 12,603 | BNLYBF3 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $113,315.70 | 2,334 | B72ZBG4 |
| 0.15% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $112,834.28 | 5,044 | BKX9VD3 |
| 0.15% | KOD | KODIAK SCIENCES INC | -- | $108,476.28 | 2,484 | BFXC933 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $105,080.44 | 1,732 | BMH5RL1 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $104,079.36 | 2,904 | BL55460 |
| 0.14% | VCYT | VERACYTE INC | -- | $102,871.86 | 3,237 | BFTWZY0 |
| 0.14% | ADMA | ADMA BIOLOGICS INC | -- | $102,767.00 | 9,695 | B9NSBM2 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $102,517.38 | 1,554 | BMGJZJ8 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $102,480.80 | 2,417 | BMFD115 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $100,278.75 | 3,575 | BK0VHF6 |
| 0.14% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $99,091.30 | 1,870 | BRXB0C0 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $96,717.60 | 4,788 | BKS3RS7 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $95,099.94 | 3,933 | BJ62Z18 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $91,787.90 | 10,210 | 2100362 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $91,446.75 | 7,275 | BN2R582 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $88,178.22 | 4,266 | B8DPDT7 |
| 0.12% | ZYME | ZYMEWORKS INC | -- | $84,825.84 | 3,048 | BPCQZY9 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $84,792.51 | 6,267 | BJ5FZ74 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $83,148.42 | 4,058 | BV2DHY6 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $82,695.36 | 5,412 | BFWLC09 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $82,354.32 | 3,222 | BP9N0G0 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $81,609.81 | 8,861 | BNZB1X8 |
| 0.11% | GRAL | GRAIL INC | -- | $78,708.96 | 1,584 | BSLSSX7 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $78,214.95 | 3,435 | BMX9K07 |
| 0.11% | PHVS | PHARVARIS NV | -- | $77,796.64 | 2,608 | BMZ2X38 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $75,344.08 | 2,324 | BJQ05Z6 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $74,082.33 | 3,591 | BN7Q7R7 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $73,768.62 | 591 | BNSP8K3 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $73,381.02 | 2,172 | BMVNDH9 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,122.75 | 2,355 | BKSGZN7 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $72,112.76 | 5,218 | BJH9ZN0 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $71,186.61 | 913 | BCDWBX6 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $70,381.86 | 1,129 | BDRW1L7 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $70,111.80 | 21,246 | BM9FJ13 |
| 0.10% | TSHA | TAYSHA GENE THERAPIES INC | -- | $69,897.96 | 11,148 | BNC1BX1 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $69,763.20 | 4,472 | BPCK358 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $69,529.46 | 4,186 | BMVLGP2 |
| 0.10% | INVA | INNOVIVA INC | -- | $69,472.70 | 3,014 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $69,099.81 | 2,067 | BSBMN89 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $68,434.31 | 2,621 | BBC9WC7 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $68,047.74 | 1,818 | BQKXDX4 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $66,871.20 | 2,384 | BCBVTX1 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $64,471.68 | 6,396 | BK4PZ38 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $64,053.00 | 1,941 | BR3T9B6 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $60,905.96 | 14,783 | BWJDYK1 |
| 0.08% | HROW | HARROW INC | -- | $60,802.64 | 1,511 | BHNDW86 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,985.81 | 9,981 | BN89V40 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $59,835.56 | 4,808 | BYZM6C2 |
| 0.08% | PGEN | PRECIGEN INC | -- | $59,344.48 | 14,404 | BKM5C84 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $58,125.60 | 3,105 | BP7KZP7 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $55,502.08 | 16,768 | BF0DMK7 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $55,259.76 | 4,632 | BYSS4X4 |
| 0.08% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $54,886.86 | 2,058 | BD06CS0 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $54,881.12 | 2,579 | BQB42F1 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $54,024.15 | 7,663 | BYZG9R0 |
| 0.07% | NVAX | NOVAVAX INC | -- | $52,833.13 | 6,629 | BJDQXG4 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $52,241.86 | 1,826 | BQXJKH2 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $50,544.10 | 1,682 | BMGTLY5 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,281.44 | 1,958 | BSRK699 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $49,809.28 | 1,784 | BLCD809 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $48,480.04 | 3,362 | BYP80F1 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $48,398.16 | 2,526 | BP6C0S2 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $47,138.80 | 12,340 | BL53SR3 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $46,110.54 | 3,261 | BMZ4LN0 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $44,439.36 | 1,904 | BZ7PJQ1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $44,368.50 | 13,445 | BPNTJ34 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $44,047.50 | 839 | BL95N25 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $43,617.92 | 1,292 | BX7RSN3 |
| 0.06% | EYPT | EYEPOINT INC | -- | $43,325.34 | 3,369 | BMGS7L1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $42,702.45 | 1,821 | BQNKXX2 |
| 0.06% | QURE | UNIQURE NV | -- | $42,427.28 | 2,536 | BJFSR88 |
| 0.06% | OMER | OMEROS CORP | -- | $41,991.04 | 2,884 | B4NB858 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,355.30 | 1,645 | B3X26D8 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,659.08 | 6,754 | BLR7H87 |
| 0.05% | SVRA | SAVARA INC | -- | $40,182.25 | 8,285 | BYXGN81 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,180.80 | 3,805 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,928.98 | 1,846 | BNFWZS4 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $39,257.33 | 4,963 | B8K7T65 |
| 0.05% | GERN | GERON CORP | -- | $39,237.35 | 25,985 | 2370381 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $38,943.45 | 2,219 | BQB42H3 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $38,571.84 | 4,086 | BKVDFF7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,766.68 | 3,206 | BJLKVS6 |
| 0.05% | DSGN | DESIGN THERAPEUTICS INC | -- | $36,585.43 | 2,317 | BMFK3H6 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $35,239.75 | 10,843 | BMFJJ97 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $34,950.47 | 2,477 | BMFX8Y7 |
| 0.05% | XNCR | XENCOR INC | -- | $34,708.94 | 2,987 | BGCYWN8 |
| 0.05% | ANNX | ANNEXON INC | -- | $34,697.99 | 5,891 | BMVV9R5 |
| 0.05% | MNKD | MANNKIND CORP | -- | $34,490.50 | 12,542 | BF081J4 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,406.88 | 2,064 | BMNDK09 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $33,105.95 | 2,129 | BQS7491 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,329.64 | 7,828 | BZ0QMB7 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $32,179.20 | 3,840 | BMC3HS7 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,556.00 | 4,025 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $30,992.50 | 3,542 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,917.10 | 2,406 | BM90J52 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $29,791.62 | 1,767 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,330.40 | 1,210 | BKLCWZ3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,320.20 | 3,276 | BFYQFJ2 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $28,946.25 | 1,395 | BD9GVY0 |
| 0.04% | ABSI | ABSCI CORP | -- | $28,829.91 | 6,121 | BN94K69 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $27,928.80 | 6,896 | BYWVTY5 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,485.45 | 6,623 | B3MZ6K5 |
| 0.04% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $26,689.56 | 1,129 | BS2CR64 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $25,934.91 | 7,347 | BPBJFM7 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $25,725.78 | 1,091 | BGL0JK3 |
| 0.03% | ARVN | ARVINAS INC | -- | $25,571.28 | 2,604 | BDZ30Q0 |
| 0.03% | CRMD | CORMEDIX INC | -- | $23,980.88 | 3,206 | BJ0LT31 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,794.43 | 2,189 | B91XRN2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,752.79 | 1,693 | BRJJYT3 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $22,376.70 | 3,174 | BQHN6C7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,144.30 | 2,290 | BLFBZ32 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,934.29 | 4,907 | BYV2W40 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $21,652.02 | 741 | BQD3J33 |
| 0.03% | PSNL | PERSONALIS INC | -- | $21,465.36 | 4,259 | BJQ0608 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $20,733.84 | 5,958 | BMCWKZ2 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,708.55 | 765 | BPBPCG8 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,208.81 | 2,199 | BRCFFK6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,104.20 | 4,964 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,843.20 | 1,560 | BP81RK8 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $19,530.00 | 2,325 | BSMLR16 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $19,376.50 | 2,710 | BJDX8Z9 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $19,302.28 | 9,148 | BFZNYB7 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $19,178.46 | 4,419 | BMXNGZ6 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,042.28 | 2,348 | B2Q9833 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,582.39 | 9,729 | BBNBTD2 |
| 0.03% | CADL | CANDEL THERAPEUTICS INC | -- | $18,391.68 | 2,976 | BP0TQC5 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $18,280.75 | 2,075 | BKLXFX5 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $18,069.24 | 12,292 | B4N8MH9 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $17,819.00 | 865 | BTNMG41 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,390.32 | 2,584 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $17,312.40 | 2,061 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,256.54 | 3,178 | BLN9Z50 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $17,039.85 | 2,417 | B12W3P6 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $16,875.28 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $16,827.44 | 604 | B292NQ7 |
| 0.02% | NGNE | NEUROGENE INC | -- | $16,655.92 | 629 | BS2F741 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,394.34 | 1,182 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,476.12 | 2,069 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,381.60 | 4,420 | BDFKQ07 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,338.08 | 11,278 | BM8NHS1 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,306.75 | 6,803 | BN4JN37 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $14,917.56 | 1,239 | BPRBTY7 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $13,764.00 | 1,240 | BM7V485 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,697.25 | 2,609 | BMVBZF5 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,664.84 | 2,638 | BDRJH21 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $13,587.21 | 1,911 | BL5B6Z1 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,402.48 | 5,096 | BFY7DC4 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,209.48 | 2,916 | 2107437 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,303.24 | 3,774 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,004.21 | 4,097 | BZC0D70 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,520.65 | 1,273 | BQV0J03 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,514.06 | 8,166 | BFMLGR4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,343.08 | 2,383 | BMF7DT9 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,206.68 | 3,974 | BZ8FPH3 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $10,886.48 | 3,916 | BK5MWR1 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $10,861.80 | 1,263 | BP2NYN2 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,737.15 | 4,569 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,586.16 | 6,084 | BRK0149 |
| 0.01% | CDXS | CODEXIS INC | -- | $10,329.56 | 3,676 | B5LL2C2 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $10,168.32 | 3,972 | BKX9NQ0 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,718.80 | 1,157 | BKC9SX3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,911.32 | 1,884 | BKDQKM6 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,736.00 | 2,400 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,732.40 | 2,298 | BPRB2N7 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $8,001.56 | 3,362 | BDDVW37 |
| 0.01% | OABI | OMNIAB INC | -- | $7,966.88 | 5,858 | BN13S71 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,523.62 | 1,523 | 2517058 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,301.76 | 3,803 | BNYJR68 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,038.17 | 2,179 | BP7L561 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $6,878.62 | 7,954 | BNR5QT9 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,583.60 | 3,020 | BPTK6Z2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,442.74 | 7,857 | BMYTJP4 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,957.26 | 2,318 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,825.83 | 8,823 | BNNXX52 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,616.06 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,340.00 | 2,800 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,208.10 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,468.67 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,292.88 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.75% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,403,380 | -- | 4,415 | -- |
| 27.74% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,276,673 | -- | 3,524 | -- |
| 26.68% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 19,499,899 | -- | 3,389 | -- |
| 20.77% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,184,489 | -- | 2,639 | -- |
| 17.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,664,290 | -- | 2,201 | -- |
| 4.98% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,642,206 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $23,573,717.50 | 23,573,718 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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