BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View all
Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 7/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 10.19% | 6.76% | -8.68% | 0.27% | -23.18% | -0.36% | -5.86% | -6.05% | 13.44% | 04/07/2010 |
| BIB NAV | 10.39% | 6.81% | -8.47% | 0.46% | -23.08% | -0.27% | -5.82% | -6.03% | 13.44% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/15/2025- NAV $55.89
- NAV Change $+1.13
- Market Price $55.87
- Market Price Change $+1.07
- Trading Volume (M) 3,671
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/15/2025- NAV $55.89
- NAV Change $+1.13
- Market Price $55.87
- Market Price Change $+1.07
- Trading Volume (M) 3,671
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 8/15/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.93% | GILD | GILEAD SCIENCES INC | -- | $2,783,470.55 | 23,515 | 2369174 |
| 4.72% | AMGN | AMGEN INC | -- | $2,662,893.54 | 8,982 | 2023607 |
| 4.07% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,300,178.24 | 5,856 | 2931034 |
| 4.04% | REGN | REGENERON PHARMACEUTICALS | -- | $2,281,030.08 | 3,936 | 2730190 |
| 3.38% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,907,867.50 | 4,250 | B00FWN1 |
| 3.10% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,749,498.66 | 22,098 | 2989044 |
| 1.54% | INSM | INSMED INC | -- | $870,957.00 | 6,815 | 2614487 |
| 1.37% | ARGX | ARGENX SE - ADR | -- | $771,519.40 | 1,180 | BDVLM39 |
| 1.35% | BIIB | BIOGEN INC | -- | $759,805.20 | 5,482 | 2455965 |
| 1.31% | SMMT | SUMMIT THERAPEUTICS INC | -- | $741,608.34 | 27,786 | BMTVQS7 |
| 1.12% | INCY | INCYTE CORP | -- | $629,474.64 | 7,242 | 2471950 |
| 1.05% | ILMN | ILLUMINA INC | -- | $592,951.53 | 5,923 | 2613990 |
| 1.02% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $573,057.75 | 15,765 | BMVP7Y0 |
| 0.94% | UTHR | UNITED THERAPEUTICS CORP | -- | $528,563.44 | 1,688 | 2430412 |
| 0.93% | SNY | SANOFI-ADR | -- | $523,928.79 | 10,527 | 2964557 |
| 0.88% | ONC | BEONE MEDICINES LTD-ADR | -- | $496,501.20 | 1,545 | BYYWPW6 |
| 0.87% | MEDP | MEDPACE HOLDINGS INC | -- | $492,188.75 | 1,075 | BDCBC61 |
| 0.87% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $492,128.70 | 3,703 | 2623911 |
| 0.83% | VTRS | VIATRIS INC | -- | $465,906.32 | 43,912 | BMWS3X9 |
| 0.82% | TEM | TEMPUS AI INC | -- | $463,928.64 | 6,288 | BSLSJJ0 |
| 0.80% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $450,186.40 | 2,270 | BV9G6B8 |
| 0.75% | BNTX | BIONTECH SE-ADR | -- | $424,337.76 | 3,738 | BK6H543 |
| 0.73% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $412,849.50 | 7,175 | 2437071 |
| 0.72% | MRNA | MODERNA INC | -- | $405,421.38 | 14,469 | BGSXTS3 |
| 0.69% | EXEL | EXELIXIS INC | -- | $390,762.00 | 10,200 | 2576941 |
| 0.65% | BBIO | BRIDGEBIO PHARMA INC | -- | $364,577.28 | 7,104 | BK1KWG8 |
| 0.55% | HALO | HALOZYME THERAPEUTICS INC | -- | $310,114.70 | 4,610 | 2975098 |
| 0.55% | VRNA | VERONA PHARMA PLC - ADR | -- | $309,809.61 | 2,943 | BYWPZK5 |
| 0.54% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $307,337.04 | 831 | BD59BS7 |
| 0.53% | ROIV | ROIVANT SCIENCES LTD | -- | $301,392.90 | 25,434 | BMW4NZ9 |
| 0.48% | GH | GUARDANT HEALTH INC | -- | $272,908.80 | 4,635 | BFXC911 |
| 0.48% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $271,695.39 | 2,307 | B4Q5ZN4 |
| 0.46% | IONS | IONIS PHARMACEUTICALS INC | -- | $260,709.90 | 5,955 | BDJ0LS6 |
| 0.45% | RVMD | REVOLUTION MEDICINES INC | -- | $253,114.08 | 6,969 | BL71K91 |
| 0.41% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $232,311.80 | 2,380 | BF2YWG4 |
| 0.37% | RNA | AVIDITY BIOSCIENCES INC | -- | $209,579.70 | 4,510 | BMWHPY1 |
| 0.36% | AXSM | AXSOME THERAPEUTICS INC | -- | $201,174.03 | 1,842 | BYZR4X4 |
| 0.34% | CRSP | CRISPR THERAPEUTICS AG | -- | $192,987.63 | 3,231 | BDHF4K6 |
| 0.33% | NUVL | NUVALENT INC-A | -- | $188,807.32 | 2,483 | BMVBZD3 |
| 0.32% | ALKS | ALKERMES PLC | -- | $179,354.70 | 6,174 | B3P6D26 |
| 0.31% | MRUS | MERUS NV | -- | $174,177.50 | 2,590 | BZBY005 |
| 0.31% | CYTK | CYTOKINETICS INC | -- | $172,777.56 | 4,468 | BBBSBJ5 |
| 0.29% | KRYS | KRYSTAL BIOTECH INC | -- | $162,441.87 | 1,081 | BD6JX35 |
| 0.28% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $158,616.46 | 6,262 | 2713317 |
| 0.28% | PCVX | VAXCYTE INC | -- | $157,842.90 | 4,827 | BKPVGH6 |
| 0.27% | ACLX | ARCELLX INC | -- | $152,752.96 | 2,062 | BPCJ1Q2 |
| 0.27% | ADMA | ADMA BIOLOGICS INC | -- | $151,754.68 | 8,932 | B9NSBM2 |
| 0.26% | AKRO | AKERO THERAPEUTICS INC | -- | $147,300.54 | 2,983 | BK7Y2V9 |
| 0.26% | PTCT | PTC THERAPEUTICS INC | -- | $144,751.30 | 2,965 | B17VCN9 |
| 0.23% | APLS | APELLIS PHARMACEUTICALS INC | -- | $130,480.50 | 4,702 | BYTQ6X1 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $130,026.33 | 2,319 | BDCBCD8 |
| 0.22% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $125,874.29 | 1,853 | BJDX8Y8 |
| 0.20% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $114,600.00 | 3,056 | BMX9K07 |
| 0.20% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $111,568.32 | 3,552 | BFZQ0L8 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $110,810.70 | 11,726 | BFNF1D6 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $109,758.33 | 2,871 | BRJ3GY4 |
| 0.19% | INDV | INDIVIOR PLC | -- | $109,511.28 | 4,668 | BP0BQQ5 |
| 0.19% | LGND | LIGAND PHARMACEUTICALS | -- | $109,079.76 | 722 | 2501578 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $107,673.60 | 3,505 | BDD19F8 |
| 0.19% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $105,975.17 | 5,167 | BYQBFJ8 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $105,294.00 | 4,200 | BP8JSP4 |
| 0.19% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $105,013.53 | 3,537 | BJ62Z18 |
| 0.18% | KYMR | KYMERA THERAPEUTICS INC | -- | $103,846.68 | 2,436 | BMPRZV5 |
| 0.17% | IMVT | IMMUNOVANT INC | -- | $97,331.90 | 6,395 | BJRFSB7 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $89,435.55 | 2,095 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $88,544.60 | 2,930 | BFTWZY0 |
| 0.15% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $86,278.81 | 14,953 | BM9FJ13 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $85,255.40 | 11,521 | B19FQ48 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $85,218.12 | 1,572 | BMH5RL1 |
| 0.15% | IBRX | IMMUNITYBIO INC | -- | $84,206.10 | 33,022 | BNSP0B8 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $80,200.67 | 2,167 | BCBVTX1 |
| 0.14% | SRPT | SAREPTA THERAPEUTICS INC | -- | $80,195.37 | 3,677 | B8DPDT7 |
| 0.14% | ALVO | ALVOTECH SA | -- | $80,113.58 | 9,983 | BPNTJ34 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $79,953.30 | 5,439 | BD2B4V0 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $79,729.41 | 3,277 | BK0VHF6 |
| 0.14% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $79,196.76 | 2,148 | BKSGZN7 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $77,578.56 | 1,296 | BMGJZJ8 |
| 0.14% | ZLAB | ZAI LAB LTD-ADR | -- | $77,391.18 | 2,166 | BD9GVY0 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $75,329.40 | 4,460 | BKX9VD3 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $75,215.20 | 5,960 | BNZB1X8 |
| 0.13% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $74,119.36 | 5,684 | BJ5FZ74 |
| 0.13% | CGON | CG ONCOLOGY INC | -- | $73,296.40 | 2,852 | BRBCSP4 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $70,850.70 | 810 | BCDWBX6 |
| 0.12% | VCEL | VERICEL CORP | -- | $68,351.52 | 1,884 | BSBMN89 |
| 0.12% | BEAM | BEAM THERAPEUTICS INC | -- | $67,074.48 | 3,764 | BK6L288 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $65,528.73 | 7,829 | 2100362 |
| 0.11% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $64,492.65 | 3,573 | BLB0YQ9 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $64,138.80 | 1,720 | BM9HHL5 |
| 0.11% | TWST | TWIST BIOSCIENCE CORP | -- | $63,045.04 | 2,242 | BGKG6G7 |
| 0.11% | TVTX | TRAVERE THERAPEUTICS INC | -- | $62,538.86 | 3,323 | BLFGJD5 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $62,024.85 | 5,055 | BFWLC09 |
| 0.10% | NVAX | NOVAVAX INC | -- | $58,054.80 | 6,060 | BJDQXG4 |
| 0.10% | WVE | WAVE LIFE SCIENCES LTD | -- | $56,285.92 | 5,767 | BYZG9R0 |
| 0.10% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $55,666.10 | 3,934 | BKY5JZ8 |
| 0.10% | JANX | JANUX THERAPEUTICS INC | -- | $55,593.54 | 2,214 | BMFX8Y7 |
| 0.10% | TXG | 10X GENOMICS INC-CLASS A | -- | $55,524.16 | 4,156 | BKS3RS7 |
| 0.09% | ARDX | ARDELYX INC | -- | $53,437.47 | 8,951 | BN89V40 |
| 0.09% | SPRY | ARS PHARMACEUTICALS INC | -- | $53,397.75 | 3,675 | BMCR7V2 |
| 0.09% | HROW | HARROW INC | -- | $53,299.86 | 1,373 | BHNDW86 |
| 0.09% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $52,873.92 | 1,584 | BRXB0C0 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $52,652.14 | 4,253 | BN15WD1 |
| 0.09% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $52,620.12 | 1,764 | BNFWZS4 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $51,394.44 | 2,386 | BL55460 |
| 0.09% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,256.53 | 11,167 | BL53SR3 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $50,667.06 | 3,219 | BN7Q7R7 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $50,651.40 | 4,260 | BLR6XK8 |
| 0.09% | ETNB | 89BIO INC | -- | $50,414.26 | 5,462 | BK1K484 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $49,544.11 | 3,619 | BDGMC59 |
| 0.09% | INVA | INNOVIVA INC | -- | $49,141.08 | 2,349 | BDDXF67 |
| 0.09% | GRFS | GRIFOLS SA-ADR | -- | $48,926.08 | 4,564 | B8K7T65 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $48,925.83 | 4,171 | BYSS4X4 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $48,892.56 | 1,487 | BLCD809 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $48,479.47 | 4,493 | BRJZSK0 |
| 0.08% | CVAC | CUREVAC NV | -- | $46,163.52 | 8,424 | BN4RD42 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $46,018.56 | 5,992 | BLR7H87 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $45,401.22 | 1,203 | BX7RSN3 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $44,847.48 | 2,229 | BQS9486 |
| 0.08% | GRAL | GRAIL INC | -- | $43,650.78 | 1,346 | BSLSSX7 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,918.96 | 1,732 | B3X26D8 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $42,575.26 | 3,874 | BYZM6C2 |
| 0.08% | MNKD | MANNKIND CORP | -- | $42,413.83 | 11,371 | BF081J4 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $39,856.05 | 1,053 | BQV0J03 |
| 0.07% | SYRE | SPYRE THERAPEUTICS INC | -- | $38,273.10 | 2,258 | BQBBDY8 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $37,436.52 | 2,607 | BPCQZY9 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $37,203.03 | 2,043 | BJQ05Z6 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $37,123.92 | 1,836 | BMFD115 |
| 0.06% | GMAB | GENMAB A/S -SP ADR | -- | $36,573.39 | 1,569 | BBC9WC7 |
| 0.06% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $35,874.96 | 762 | BQ721R4 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $35,399.76 | 2,438 | BP9N0G0 |
| 0.06% | GERN | GERON CORP | -- | $34,553.50 | 23,830 | 2370381 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $33,999.75 | 1,725 | BZ7PJQ1 |
| 0.06% | QURE | UNIQURE NV | -- | $33,136.64 | 2,048 | BJFSR88 |
| 0.06% | CRMD | CORMEDIX INC | -- | $32,816.34 | 2,538 | BJ0LT31 |
| 0.06% | PGEN | PRECIGEN INC | -- | $32,469.36 | 11,044 | BKM5C84 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $31,859.70 | 12,494 | BF0DMK7 |
| 0.06% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $31,764.33 | 3,194 | BYTYP72 |
| 0.05% | NRIX | NURIX THERAPEUTICS INC | -- | $30,174.16 | 2,852 | BMVLGP2 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $28,714.98 | 9,767 | BNC1BX1 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $28,628.64 | 3,807 | BJH9ZN0 |
| 0.05% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $28,556.75 | 2,575 | BMGS7L1 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $28,101.87 | 8,439 | BMFJJ97 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $27,625.00 | 1,700 | BQS7491 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $27,452.35 | 4,055 | BP2P6L0 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $27,223.44 | 3,386 | BRXYZ57 |
| 0.05% | MNMD | MIND MEDICINE MINDMED INC | -- | $27,167.47 | 2,827 | BPQYY97 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $26,746.88 | 2,612 | BJLKVS6 |
| 0.05% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $26,680.00 | 3,335 | BPCK358 |
| 0.05% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $26,432.19 | 669 | BQD3J33 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $25,695.60 | 2,660 | BKVDFF7 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $25,596.00 | 3,792 | BLB0YH0 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $24,998.40 | 1,280 | BMGTLY5 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,603.65 | 1,871 | BMNDK09 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $24,567.19 | 3,007 | BFYQFJ2 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $24,113.59 | 7,166 | BZ0QMB7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $23,956.80 | 1,860 | BD06CS0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $23,774.26 | 3,239 | BYZD465 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $23,377.44 | 5,172 | BK4PZ38 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $23,370.54 | 762 | BL95N25 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $23,039.40 | 3,268 | BMDJ0C9 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,720.50 | 2,673 | 2107437 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $22,705.56 | 6,414 | BN2R582 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $22,133.86 | 1,099 | BDRW1L7 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,009.60 | 1,520 | BM7V485 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $21,697.20 | 1,080 | BKLCWZ3 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $21,689.77 | 961 | BQ80NC6 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $21,533.37 | 1,401 | BKVF0J2 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $21,352.70 | 1,990 | BMVNDH9 |
| 0.04% | XNCR | XENCOR INC | -- | $20,451.84 | 2,663 | BGCYWN8 |
| 0.04% | RAPP | RAPPORT THERAPEUTICS INC | -- | $20,087.03 | 1,366 | BR3T9B6 |
| 0.04% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $19,772.20 | 1,015 | BKC9SX3 |
| 0.03% | SVRA | SAVARA INC | -- | $19,656.64 | 6,466 | BYXGN81 |
| 0.03% | ARVN | ARVINAS INC | -- | $19,362.79 | 2,731 | BDZ30Q0 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $19,293.78 | 2,046 | BLFBZ32 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $19,082.00 | 1,160 | BYXV9H7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,988.38 | 554 | B292NQ7 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $17,719.00 | 2,900 | BQHN6C7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $17,535.84 | 4,912 | BPBJFM7 |
| 0.03% | ERAS | ERASCA INC | -- | $17,382.36 | 10,599 | BNLYBF3 |
| 0.03% | ALMS | ALUMIS INC | -- | $16,986.00 | 3,576 | BPLQG36 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $16,936.26 | 2,211 | BM90J52 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $16,849.12 | 13,588 | BWFZX59 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $16,615.50 | 2,014 | B91XRN2 |
| 0.03% | RGNX | REGENXBIO INC | -- | $16,555.14 | 1,877 | BZ0G875 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $16,433.49 | 699 | BPBPCG8 |
| 0.03% | EOLS | EVOLUS INC | -- | $16,232.76 | 2,412 | BDRJH21 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $16,035.04 | 2,884 | BDDVW37 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,665.55 | 2,885 | BYP80F1 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $15,590.40 | 2,320 | BP81R42 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $15,272.76 | 3,716 | BYVQJ96 |
| 0.03% | PSNL | PERSONALIS INC | -- | $15,203.00 | 3,305 | BJQ0608 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $15,200.75 | 7,415 | BBNBTD2 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,707.37 | 11,227 | B4N8MH9 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $14,688.00 | 3,400 | BMC3HS7 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $14,477.52 | 1,432 | BMWXFT4 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,460.35 | 2,111 | BMYRFN8 |
| 0.03% | YMAB | Y-MABS THERAPEUTICS INC | -- | $14,441.40 | 1,695 | BG31GH0 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $14,105.60 | 2,560 | BMZ4LN0 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $14,060.07 | 5,387 | BMCWKZ2 |
| 0.02% | ABSI | ABSCI CORP | -- | $13,981.96 | 4,772 | BN94K69 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,353.56 | 7,502 | BFMLGR4 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $12,644.86 | 542 | BNSP8K3 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $12,581.58 | 1,733 | BKLXFX5 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,294.55 | 4,031 | BDFKQ07 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $12,283.44 | 1,651 | BKDQKM6 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $11,721.85 | 749 | BN72KB0 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,320.92 | 2,124 | BMFK3H6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,207.00 | 3,202 | BLN9Z50 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $11,017.05 | 3,035 | BFY7DC4 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $11,001.43 | 971 | BQB9HM8 |
| 0.02% | NGNE | NEUROGENE INC | -- | $10,952.34 | 534 | BS2F741 |
| 0.02% | HUMA | HUMACYTE INC | -- | $10,911.52 | 5,804 | BMYTJP4 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,538.58 | 2,301 | BP7KZP7 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $10,383.30 | 2,085 | BMF7DT9 |
| 0.02% | ANNX | ANNEXON INC | -- | $10,016.20 | 4,105 | BMVV9R5 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,864.76 | 6,052 | BN4JN37 |
| 0.02% | OMER | OMEROS CORP | -- | $9,666.72 | 2,192 | B4NB858 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,653.60 | 1,760 | BL5B6Z1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,613.80 | 2,205 | B12W3P6 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,607.96 | 2,396 | BMXNGZ6 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $9,489.96 | 3,132 | BZ8FPH3 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $9,375.31 | 1,999 | BP7L561 |
| 0.02% | CDXS | CODEXIS INC | -- | $9,331.00 | 3,100 | B5LL2C2 |
| 0.02% | OABI | OMNIAB INC | -- | $9,199.77 | 4,577 | BN13S71 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $9,085.00 | 1,975 | BYX2Z16 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $9,002.40 | 8,184 | BFZNYB7 |
| 0.01% | ALEC | ALECTOR INC | -- | $8,417.25 | 3,741 | BJ4LDC4 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $8,002.41 | 3,757 | BZC0D70 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $7,721.10 | 2,070 | BY7RB53 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,472.86 | 1,418 | BP81RK8 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,536.22 | 2,657 | BKX9NQ0 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $6,524.30 | 6,880 | BPG5P75 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,400.00 | 800 | B9L5200 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $6,235.62 | 6,054 | B3MZ6K5 |
| 0.01% | NKTX | NKARTA INC | -- | $6,186.15 | 2,655 | BK80YJ8 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $5,862.24 | 1,242 | BQ6C357 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $5,840.16 | 552 | BTNMG41 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,675.67 | 1,617 | BSMLR16 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,410.08 | 3,978 | BKMQF66 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,803.20 | 2,528 | BMW5LX6 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $4,675.01 | 4,289 | BCZS820 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,728.80 | 2,360 | BFDV8K0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,560.35 | 2,297 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,522.60 | 1,957 | BNLYBJ7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $2,851.14 | 2,318 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,774.48 | 3,160 | BF12XC2 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,537.79 | 5,297 | BJL38Z1 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,508.00 | 912 | BMF1LJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,432.38 | 1,406 | BNKF6N0 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,583.55 | 1,173 | BP2TPK4 |
| -- | PEPG | PEPGEN INC | -- | $1,578.96 | 1,224 | BMTX3D7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,338.92 | 187 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,214.40 | 480 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $898.32 | 456 | BS2FKQ4 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 30.61% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,276,910 | -- | 3,675 | -- |
| 29.04% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 16,393,084 | -- | 3,487 | -- |
| 26.04% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 14,700,652 | -- | 3,127 | -- |
| 16.65% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 9,397,699 | -- | 1,999 | -- |
| 16.02% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,045,109 | -- | 1,924 | -- |
| 15.98% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,021,603 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,969,919.45 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $14,573,582.82 | 14,573,583 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Earnings Ratio--
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More