BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 7/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 10.19% | 6.76% | -8.68% | 0.27% | -23.18% | -0.36% | -5.86% | -6.05% | 13.44% | 04/07/2010 |
| BIB NAV | 10.39% | 6.81% | -8.47% | 0.46% | -23.08% | -0.27% | -5.82% | -6.03% | 13.44% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/08/2025- NAV $58.07
- NAV Change $-1.13
- Market Price $58.07
- Market Price Change $-1.18
- Trading Volume (M) 8,809
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 9/08/2025- NAV $58.07
- NAV Change $-1.13
- Market Price $58.07
- Market Price Change $-1.18
- Trading Volume (M) 8,809
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 9/08/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.54% | GILD | GILEAD SCIENCES INC | -- | $2,559,905.08 | 22,091 | 2369174 |
| 4.20% | AMGN | AMGEN INC | -- | $2,364,243.22 | 8,438 | 2023607 |
| 3.86% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,173,875.00 | 5,500 | 2931034 |
| 3.66% | REGN | REGENERON PHARMACEUTICALS | -- | $2,063,994.24 | 3,696 | 2730190 |
| 3.23% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,817,389.82 | 3,994 | B00FWN1 |
| 3.01% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,693,022.48 | 20,758 | 2989044 |
| 1.67% | INSM | INSMED INC | -- | $939,192.04 | 6,403 | 2614487 |
| 1.51% | ARGX | ARGENX SE - ADR | -- | $850,944.00 | 1,108 | BDVLM39 |
| 1.29% | BIIB | BIOGEN INC | -- | $727,952.50 | 5,150 | 2455965 |
| 1.11% | UTHR | UNITED THERAPEUTICS CORP | -- | $625,078.08 | 1,584 | 2430412 |
| 1.05% | INCY | INCYTE CORP | -- | $588,781.12 | 6,802 | 2471950 |
| 0.97% | ILMN | ILLUMINA INC | -- | $546,175.34 | 5,563 | 2613990 |
| 0.94% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $530,162.20 | 14,809 | BMVP7Y0 |
| 0.90% | SMMT | SUMMIT THERAPEUTICS INC | -- | $507,553.39 | 26,102 | BMTVQS7 |
| 0.89% | ONC | BEONE MEDICINES LTD-ADR | -- | $503,391.85 | 1,453 | BYYWPW6 |
| 0.89% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $500,280.20 | 3,479 | 2623911 |
| 0.88% | MEDP | MEDPACE HOLDINGS INC | -- | $497,502.99 | 1,011 | BDCBC61 |
| 0.84% | TEM | TEMPUS AI INC | -- | $473,939.76 | 5,908 | BSLSJJ0 |
| 0.82% | SNY | SANOFI-ADR | -- | $462,898.80 | 9,891 | 2964557 |
| 0.78% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $437,939.48 | 2,134 | BV9G6B8 |
| 0.77% | VTRS | VIATRIS INC | -- | $432,320.96 | 41,252 | BMWS3X9 |
| 0.67% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $379,944.82 | 6,739 | 2437071 |
| 0.64% | BBIO | BRIDGEBIO PHARMA INC | -- | $362,222.88 | 6,672 | BK1KWG8 |
| 0.64% | EXEL | EXELIXIS INC | -- | $361,220.96 | 9,584 | 2576941 |
| 0.64% | BNTX | BIONTECH SE-ADR | -- | $360,336.60 | 3,510 | BK6H543 |
| 0.63% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $353,510.20 | 779 | BD59BS7 |
| 0.61% | IONS | IONIS PHARMACEUTICALS INC | -- | $341,295.00 | 5,595 | BDJ0LS6 |
| 0.60% | MRNA | MODERNA INC | -- | $337,514.19 | 13,593 | BGSXTS3 |
| 0.58% | HALO | HALOZYME THERAPEUTICS INC | -- | $328,430.50 | 4,330 | 2975098 |
| 0.55% | ROIV | ROIVANT SCIENCES LTD | -- | $308,471.54 | 23,894 | BMW4NZ9 |
| 0.52% | VRNA | VERONA PHARMA PLC - ADR | -- | $293,706.90 | 2,763 | BYWPZK5 |
| 0.50% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $281,384.95 | 2,167 | B4Q5ZN4 |
| 0.48% | RVMD | REVOLUTION MEDICINES INC | -- | $268,737.70 | 6,545 | BL71K91 |
| 0.47% | GH | GUARDANT HEALTH INC | -- | $262,018.58 | 4,355 | BFXC911 |
| 0.40% | AXSM | AXSOME THERAPEUTICS INC | -- | $223,671.70 | 1,730 | BYZR4X4 |
| 0.40% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $223,085.72 | 2,236 | BF2YWG4 |
| 0.39% | CYTK | CYTOKINETICS INC | -- | $218,569.64 | 4,196 | BBBSBJ5 |
| 0.36% | RNA | AVIDITY BIOSCIENCES INC | -- | $203,635.90 | 4,238 | BMWHPY1 |
| 0.33% | NUVL | NUVALENT INC-A | -- | $186,083.73 | 2,331 | BMVBZD3 |
| 0.29% | ALKS | ALKERMES PLC | -- | $165,066.90 | 5,802 | B3P6D26 |
| 0.29% | CRSP | CRISPR THERAPEUTICS AG | -- | $164,193.50 | 3,035 | BDHF4K6 |
| 0.29% | MRUS | MERUS NV | -- | $163,540.46 | 2,434 | BZBY005 |
| 0.28% | PTCT | PTC THERAPEUTICS INC | -- | $158,605.75 | 2,785 | B17VCN9 |
| 0.27% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $149,343.98 | 5,882 | 2713317 |
| 0.26% | KRYS | KRYSTAL BIOTECH INC | -- | $147,668.40 | 1,017 | BD6JX35 |
| 0.26% | PCVX | VAXCYTE INC | -- | $146,979.35 | 4,535 | BKPVGH6 |
| 0.24% | ACLX | ARCELLX INC | -- | $137,811.18 | 1,938 | BPCJ1Q2 |
| 0.24% | ADMA | ADMA BIOLOGICS INC | -- | $137,796.64 | 8,392 | B9NSBM2 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $134,735.99 | 1,741 | BJDX8Y8 |
| 0.23% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $131,910.35 | 4,855 | BYQBFJ8 |
| 0.22% | AKRO | AKERO THERAPEUTICS INC | -- | $124,929.71 | 2,803 | BK7Y2V9 |
| 0.22% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $122,438.01 | 2,179 | BDCBCD8 |
| 0.21% | APLS | APELLIS PHARMACEUTICALS INC | -- | $118,888.38 | 4,418 | BYTQ6X1 |
| 0.21% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $115,716.02 | 3,293 | BDD19F8 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $112,453.08 | 678 | 2501578 |
| 0.19% | INDV | INDIVIOR PLC | -- | $108,460.16 | 4,384 | BP0BQQ5 |
| 0.19% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $107,166.22 | 11,014 | BFNF1D6 |
| 0.19% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $105,350.88 | 3,336 | BFZQ0L8 |
| 0.19% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $104,644.71 | 3,321 | BJ62Z18 |
| 0.18% | XENE | XENON PHARMACEUTICALS INC | -- | $103,074.81 | 2,699 | BRJ3GY4 |
| 0.18% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $99,428.64 | 2,872 | BMX9K07 |
| 0.18% | KYMR | KYMERA THERAPEUTICS INC | -- | $98,978.88 | 2,288 | BMPRZV5 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $98,954.96 | 3,944 | BP8JSP4 |
| 0.17% | IMVT | IMMUNOVANT INC | -- | $98,334.59 | 6,007 | BJRFSB7 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $90,289.20 | 2,680 | BRBCSP4 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $90,127.94 | 1,967 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $89,394.84 | 2,754 | BFTWZY0 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $86,383.50 | 10,825 | B19FQ48 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $83,969.64 | 1,476 | BMH5RL1 |
| 0.15% | MLYS | MINERALYS THERAPEUTICS INC | -- | $82,279.70 | 2,290 | BP9N0G0 |
| 0.14% | DNLI | DENALI THERAPEUTICS INC | -- | $79,220.50 | 5,111 | BD2B4V0 |
| 0.14% | ALVO | ALVOTECH SA | -- | $76,532.64 | 9,379 | BPNTJ34 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $75,282.56 | 1,216 | BMGJZJ8 |
| 0.13% | IBRX | IMMUNITYBIO INC | -- | $74,763.02 | 31,022 | BNSP0B8 |
| 0.13% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $74,094.35 | 2,035 | BCBVTX1 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $72,578.04 | 4,188 | BKX9VD3 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,542.40 | 762 | BCDWBX6 |
| 0.13% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,233.28 | 2,016 | BKSGZN7 |
| 0.13% | IDYA | IDEAYA BIOSCIENCES INC | -- | $71,971.03 | 3,077 | BK0VHF6 |
| 0.13% | OCUL | OCULAR THERAPEUTIX INC | -- | $71,176.00 | 5,600 | BNZB1X8 |
| 0.13% | BEAM | BEAM THERAPEUTICS INC | -- | $70,507.84 | 3,536 | BK6L288 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $66,963.60 | 5,340 | BJ5FZ74 |
| 0.12% | TVTX | TRAVERE THERAPEUTICS INC | -- | $66,207.60 | 3,123 | BLFGJD5 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $64,906.38 | 14,049 | BM9FJ13 |
| 0.11% | ZLAB | ZAI LAB LTD-ADR | -- | $63,725.22 | 2,034 | BD9GVY0 |
| 0.11% | APGE | APOGEE THERAPEUTICS INC | -- | $62,086.72 | 1,616 | BM9HHL5 |
| 0.11% | SRPT | SAREPTA THERAPEUTICS INC | -- | $60,772.80 | 3,453 | B8DPDT7 |
| 0.11% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $60,526.71 | 3,357 | BLB0YQ9 |
| 0.11% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $60,221.07 | 7,353 | 2100362 |
| 0.11% | MNKD | MANNKIND CORP | -- | $59,504.31 | 10,683 | BF081J4 |
| 0.10% | VCEL | VERICEL CORP | -- | $58,732.96 | 1,768 | BSBMN89 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $58,388.10 | 4,747 | BFWLC09 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $55,489.50 | 2,242 | BL55460 |
| 0.10% | ARDX | ARDELYX INC | -- | $55,402.13 | 8,407 | BN89V40 |
| 0.10% | TWST | TWIST BIOSCIENCE CORP | -- | $55,282.50 | 2,106 | BGKG6G7 |
| 0.10% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $54,966.72 | 3,694 | BKY5JZ8 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $54,416.16 | 1,488 | BRXB0C0 |
| 0.10% | TXG | 10X GENOMICS INC-CLASS A | -- | $54,382.72 | 3,904 | BKS3RS7 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $53,160.10 | 3,997 | BN15WD1 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $52,276.62 | 3,399 | BDGMC59 |
| 0.09% | JANX | JANUX THERAPEUTICS INC | -- | $51,555.18 | 2,078 | BMFX8Y7 |
| 0.09% | HROW | HARROW INC | -- | $51,263.53 | 1,289 | BHNDW86 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $51,112.80 | 1,395 | BLCD809 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $50,770.72 | 4,004 | BLR6XK8 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $49,379.40 | 3,919 | BYSS4X4 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $49,365.59 | 3,023 | BN7Q7R7 |
| 0.09% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $48,454.56 | 1,656 | BNFWZS4 |
| 0.09% | GRAL | GRAIL INC | -- | $48,399.18 | 1,266 | BSLSSX7 |
| 0.08% | INVA | INNOVIVA INC | -- | $45,114.30 | 2,205 | BDDXF67 |
| 0.08% | NVAX | NOVAVAX INC | -- | $43,999.16 | 5,692 | BJDQXG4 |
| 0.08% | ETNB | 89BIO INC | -- | $43,964.10 | 5,130 | BK1K484 |
| 0.08% | ABCL | ABCELLERA BIOLOGICS INC | -- | $43,747.47 | 10,491 | BL53SR3 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,729.56 | 5,628 | BLR7H87 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $43,659.98 | 2,093 | BQS9486 |
| 0.08% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,532.72 | 1,628 | B3X26D8 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $43,351.68 | 4,288 | B8K7T65 |
| 0.08% | PGEN | PRECIGEN INC | -- | $43,164.16 | 10,376 | BKM5C84 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $43,073.92 | 3,638 | BYZM6C2 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,695.25 | 1,131 | BX7RSN3 |
| 0.08% | CVAC | CUREVAC NV | -- | $42,329.20 | 7,912 | BN4RD42 |
| 0.07% | STOK | STOKE THERAPEUTICS INC | -- | $42,198.81 | 1,919 | BJQ05Z6 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $41,076.02 | 5,419 | BYZG9R0 |
| 0.07% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $40,943.70 | 4,221 | BRJZSK0 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $40,566.42 | 1,473 | BBC9WC7 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $40,344.54 | 1,282 | BR3T9B6 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $39,194.07 | 989 | BQV0J03 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $37,230.69 | 2,451 | BPCQZY9 |
| 0.07% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,925.70 | 3,451 | BMCR7V2 |
| 0.06% | SYRE | SPYRE THERAPEUTICS INC | -- | $35,288.86 | 2,122 | BQBBDY8 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $34,721.82 | 1,621 | BZ7PJQ1 |
| 0.06% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $34,514.48 | 1,724 | BMFD115 |
| 0.06% | QURE | UNIQURE NV | -- | $33,535.32 | 1,924 | BJFSR88 |
| 0.06% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $33,019.35 | 2,419 | BMGS7L1 |
| 0.06% | FTRE | FORTREA HOLDINGS INC | -- | $32,838.24 | 3,182 | BRXYZ57 |
| 0.06% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $32,729.40 | 3,135 | BPCK358 |
| 0.05% | GERN | GERON CORP | -- | $30,668.82 | 22,386 | 2370381 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $30,478.36 | 2,452 | BJLKVS6 |
| 0.05% | CRMD | CORMEDIX INC | -- | $30,421.50 | 2,386 | BJ0LT31 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $29,727.00 | 9,175 | BNC1BX1 |
| 0.05% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $29,095.50 | 714 | BQ721R4 |
| 0.05% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $28,153.02 | 714 | BL95N25 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $28,068.70 | 3,002 | BYTYP72 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $27,936.44 | 11,738 | BF0DMK7 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $27,898.08 | 1,748 | BD06CS0 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $27,542.06 | 6,734 | BZ0QMB7 |
| 0.05% | TRML | TOURMALINE BIO INC | -- | $27,192.18 | 901 | BQ80NC6 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $27,170.00 | 3,575 | BJH9ZN0 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $26,623.08 | 3,564 | BLB0YH0 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $26,250.00 | 2,500 | BKVDFF7 |
| 0.05% | NRIX | NURIX THERAPEUTICS INC | -- | $25,996.00 | 2,680 | BMVLGP2 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $25,952.91 | 3,811 | BP2P6L0 |
| 0.05% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $25,707.23 | 629 | BQD3J33 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $25,223.40 | 4,860 | BK4PZ38 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $24,930.45 | 2,655 | BPQYY97 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $24,770.02 | 3,043 | BYZD465 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $24,485.28 | 1,759 | BMNDK09 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $24,465.56 | 6,026 | BN2R582 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $24,444.96 | 1,016 | BKLCWZ3 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $24,332.84 | 1,204 | BMGTLY5 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $23,781.00 | 7,927 | BMFJJ97 |
| 0.04% | SVRA | SAVARA INC | -- | $23,384.90 | 6,074 | BYXGN81 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $23,221.80 | 1,596 | BQS7491 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $22,877.89 | 1,031 | BDRW1L7 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $22,683.10 | 1,870 | BMVNDH9 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $22,364.16 | 3,072 | BMDJ0C9 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $22,091.16 | 1,428 | BM7V485 |
| 0.04% | SIGA | SIGA TECHNOLOGIES INC | -- | $21,762.58 | 2,513 | 2107437 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $21,087.81 | 2,823 | BFYQFJ2 |
| 0.04% | XNCR | XENCOR INC | -- | $21,050.23 | 2,503 | BGCYWN8 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $20,808.60 | 1,317 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $20,381.98 | 2,567 | BDZ30Q0 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $18,222.32 | 2,404 | BMZ4LN0 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $17,956.24 | 4,616 | BPBJFM7 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $17,527.68 | 1,088 | BYXV9H7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,513.10 | 522 | B292NQ7 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $17,494.92 | 3,492 | BYVQJ96 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $17,487.17 | 6,967 | BBNBTD2 |
| 0.03% | EOLS | EVOLUS INC | -- | $17,229.04 | 2,264 | BDRJH21 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $17,037.20 | 955 | BKC9SX3 |
| 0.03% | RGNX | REGENXBIO INC | -- | $16,732.20 | 1,765 | BZ0G875 |
| 0.03% | PSNL | PERSONALIS INC | -- | $16,518.60 | 3,105 | BJQ0608 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $16,356.32 | 2,708 | BDDVW37 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $16,080.06 | 1,894 | B91XRN2 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $16,010.26 | 1,922 | BLFBZ32 |
| 0.03% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $15,983.10 | 2,709 | BYP80F1 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $15,896.16 | 3,192 | BMC3HS7 |
| 0.03% | ERAS | ERASCA INC | -- | $15,436.45 | 9,959 | BNLYBF3 |
| 0.03% | INBX | INHIBRX BIOSCIENCES INC | -- | $14,841.00 | 510 | BNSP8K3 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,733.69 | 1,983 | BMYRFN8 |
| 0.03% | ALMS | ALUMIS INC | -- | $14,515.20 | 3,360 | BPLQG36 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $14,220.36 | 2,079 | BM90J52 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $14,104.60 | 2,180 | BP81R42 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $13,974.12 | 2,724 | BQHN6C7 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $13,785.12 | 12,764 | BWFZX59 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $13,666.69 | 1,591 | BG31GH0 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $13,183.75 | 10,547 | B4N8MH9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $12,345.62 | 3,787 | BDFKQ07 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $12,343.96 | 5,059 | BMCWKZ2 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $11,616.72 | 1,996 | BMFK3H6 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $11,354.13 | 1,629 | BKLXFX5 |
| 0.02% | ABSI | ABSCI CORP | -- | $11,254.84 | 4,484 | BN94K69 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $11,252.75 | 1,957 | BMF7DT9 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $10,857.00 | 1,551 | BKDQKM6 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $10,683.05 | 655 | BPBPCG8 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,577.21 | 2,851 | BFY7DC4 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $10,416.38 | 705 | BN72KB0 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,372.80 | 2,161 | BP7KZP7 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $10,350.90 | 1,855 | BYX2Z16 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $10,075.78 | 7,046 | BFMLGR4 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $9,782.50 | 3,010 | BLN9Z50 |
| 0.02% | NGNE | NEUROGENE INC | -- | $9,763.90 | 502 | BS2F741 |
| 0.02% | ALEC | ALECTOR INC | -- | $9,695.88 | 3,513 | BJ4LDC4 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $9,435.44 | 5,684 | BN4JN37 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,432.15 | 2,073 | B12W3P6 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $9,283.09 | 911 | BQB9HM8 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,887.76 | 1,652 | BL5B6Z1 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $8,850.36 | 2,252 | BMXNGZ6 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,764.32 | 7,688 | BFZNYB7 |
| 0.02% | OMER | OMEROS CORP | -- | $8,672.60 | 2,060 | B4NB858 |
| 0.02% | ANNX | ANNEXON INC | -- | $8,523.97 | 3,857 | BMVV9R5 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $8,289.96 | 1,946 | BY7RB53 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $8,213.76 | 2,944 | BZ8FPH3 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $8,173.65 | 1,879 | BP7L561 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $7,763.80 | 3,529 | BZC0D70 |
| 0.01% | HUMA | HUMACYTE INC | -- | $7,687.32 | 5,452 | BMYTJP4 |
| 0.01% | CDXS | CODEXIS INC | -- | $7,134.40 | 2,912 | B5LL2C2 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,043.52 | 1,334 | BP81RK8 |
| 0.01% | OABI | OMNIAB INC | -- | $6,838.59 | 4,301 | BN13S71 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $6,775.60 | 520 | BTNMG41 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,766.87 | 2,497 | BKX9NQ0 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $6,700.32 | 752 | B9L5200 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $6,425.18 | 5,686 | B3MZ6K5 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $6,121.50 | 1,166 | BQ6C357 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,931.90 | 1,521 | BSMLR16 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $5,868.72 | 2,376 | BMW5LX6 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $5,683.15 | 6,464 | BPG5P75 |
| 0.01% | NKTX | NKARTA INC | -- | $5,289.40 | 2,495 | BK80YJ8 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,270.58 | 3,738 | BKMQF66 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,268.88 | 2,178 | BLBR8D5 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,900.16 | 2,216 | BFDV8K0 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $3,892.01 | 4,029 | BCZS820 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,731.61 | 2,157 | BMDWW66 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,453.56 | 1,837 | BNLYBJ7 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,915.47 | 2,968 | BF12XC2 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,645.04 | 856 | BMF1LJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,392.82 | 1,322 | BNKF6N0 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,191.37 | 4,977 | BJL38Z1 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,970.79 | 1,101 | BP2TPK4 |
| -- | PEPG | PEPGEN INC | -- | $1,710.52 | 1,148 | BMTX3D7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,232.00 | 175 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,188.76 | 452 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $749.00 | 428 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 31.32% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 17,639,963 | -- | 3,675 | -- |
| 31.29% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 17,625,563 | -- | 3,672 | -- |
| 24.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,799,971 | -- | 2,875 | -- |
| 17.13% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 9,647,980 | -- | 2,010 | -- |
| 16.40% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 9,235,181 | -- | 1,924 | -- |
| 16.35% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 9,211,181 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,983,098.45 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $15,955,284.03 | 15,955,284 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
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