BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -1.49% | -14.47% | -20.30% | -6.07% | -4.31% | -1.10% | -4.38% | -4.22% | 13.18% | 04/07/2010 |
| BIB NAV | -1.28% | -14.31% | -20.40% | -5.95% | -4.14% | -1.07% | -4.38% | -4.22% | 13.19% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -12.17% | -4.65% | -23.66% | -4.65% | -14.82% | -7.50% | 1.19% | -4.67% | 13.38% | 04/07/2010 |
| BIB NAV | -12.25% | -4.72% | -23.81% | -4.72% | -14.95% | -7.45% | 1.07% | -4.69% | 13.36% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 5/22/2025- NAV $43.17
- NAV Change $-0.26
- Market Price $43.10
- Market Price Change $-0.28
- Trading Volume (M) 6,150
- 30-Day Median Bid Ask Spread 0.30%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 5/22/2025- NAV $43.17
- NAV Change $-0.26
- Market Price $43.10
- Market Price Change $-0.28
- Trading Volume (M) 6,150
- 30-Day Median Bid Ask Spread 0.30%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2025
Holdings
as of 5/22/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.20% | GILD | GILEAD SCIENCES INC | -- | $2,754,532.44 | 25,806 | 2369174 |
| 6.00% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,668,416.44 | 6,148 | 2931034 |
| 5.86% | AMGN | AMGEN INC | -- | $2,603,714.40 | 9,576 | 2023607 |
| 5.31% | REGN | REGENERON PHARMACEUTICALS | -- | $2,360,541.75 | 3,955 | 2730190 |
| 3.37% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,498,398.95 | 21,421 | 2989044 |
| 3.10% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,376,218.00 | 4,762 | B00FWN1 |
| 1.57% | SMMT | SUMMIT THERAPEUTICS INC | -- | $699,294.72 | 27,136 | BMTVQS7 |
| 1.54% | ARGX | ARGENX SE - ADR | -- | $684,936.32 | 1,178 | BDVLM39 |
| 1.53% | BIIB | BIOGEN INC | -- | $680,125.50 | 5,385 | 2455965 |
| 1.25% | SNY | SANOFI-ADR | -- | $555,030.70 | 10,570 | 2964557 |
| 1.16% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $515,021.40 | 15,940 | BMVP7Y0 |
| 1.15% | UTHR | UNITED THERAPEUTICS CORP | -- | $510,005.44 | 1,652 | 2430412 |
| 1.06% | ILMN | ILLUMINA INC | -- | $469,306.58 | 5,827 | 2613990 |
| 1.03% | INCY | INCYTE CORP | -- | $459,246.69 | 7,119 | 2471950 |
| 0.99% | EXEL | EXELIXIS INC | -- | $441,286.56 | 10,296 | 2576941 |
| 0.99% | INSM | INSMED INC | -- | $440,493.28 | 6,658 | 2614487 |
| 0.98% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $436,932.16 | 3,668 | 2623911 |
| 0.92% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $407,114.18 | 7,018 | 2437071 |
| 0.85% | MRNA | MODERNA INC | -- | $379,236.96 | 14,193 | BGSXTS3 |
| 0.83% | VTRS | VIATRIS INC | -- | $367,974.18 | 43,911 | BMWS3X9 |
| 0.83% | ONC | BEIGENE LTD-ADR | -- | $367,451.64 | 1,539 | BYYWPW6 |
| 0.82% | TEM | TEMPUS AI INC | -- | $364,328.25 | 6,149 | BSLSJJ0 |
| 0.82% | BNTX | BIONTECH SE-ADR | -- | $362,596.20 | 3,660 | BK6H543 |
| 0.80% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $355,631.10 | 2,222 | BV9G6B8 |
| 0.74% | MEDP | MEDPACE HOLDINGS INC | -- | $328,486.63 | 1,121 | BDCBC61 |
| 0.65% | ROIV | ROIVANT SCIENCES LTD | -- | $287,164.06 | 26,249 | BMW4NZ9 |
| 0.60% | RVMD | REVOLUTION MEDICINES INC | -- | $265,353.20 | 6,839 | BL71K91 |
| 0.55% | HALO | HALOZYME THERAPEUTICS INC | -- | $243,487.50 | 4,530 | 2975098 |
| 0.54% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $240,858.71 | 2,234 | B4Q5ZN4 |
| 0.53% | BPMC | BLUEPRINT MEDICINES CORP | -- | $235,899.34 | 2,351 | BWY52P3 |
| 0.52% | BBIO | BRIDGEBIO PHARMA INC | -- | $230,658.12 | 6,996 | BK1KWG8 |
| 0.50% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $221,960.20 | 812 | BD59BS7 |
| 0.47% | VRNA | VERONA PHARMA PLC - ADR | -- | $210,728.31 | 2,899 | BYWPZK5 |
| 0.44% | IONS | IONIS PHARMACEUTICALS INC | -- | $194,504.48 | 5,848 | BDJ0LS6 |
| 0.42% | AXSM | AXSOME THERAPEUTICS INC | -- | $187,203.90 | 1,794 | BYZR4X4 |
| 0.40% | ALKS | ALKERMES PLC | -- | $179,759.10 | 5,982 | B3P6D26 |
| 0.40% | NUVL | NUVALENT INC-A | -- | $178,241.82 | 2,434 | BMVBZD3 |
| 0.39% | ADMA | ADMA BIOLOGICS INC | -- | $175,311.36 | 8,696 | B9NSBM2 |
| 0.38% | GH | GUARDANT HEALTH INC | -- | $168,207.00 | 4,540 | BFXC911 |
| 0.36% | PCVX | VAXCYTE INC | -- | $160,821.15 | 4,737 | BKPVGH6 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $144,235.26 | 2,326 | BF2YWG4 |
| 0.32% | AKRO | AKERO THERAPEUTICS INC | -- | $143,433.13 | 2,929 | BK7Y2V9 |
| 0.31% | SRPT | SAREPTA THERAPEUTICS INC | -- | $138,441.51 | 3,569 | B8DPDT7 |
| 0.31% | RNA | AVIDITY BIOSCIENCES INC | -- | $136,241.82 | 4,422 | BMWHPY1 |
| 0.30% | KRYS | KRYSTAL BIOTECH INC | -- | $132,807.40 | 1,060 | BD6JX35 |
| 0.30% | CYTK | CYTOKINETICS INC | -- | $132,792.66 | 4,356 | BBBSBJ5 |
| 0.30% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $132,209.25 | 6,135 | 2713317 |
| 0.30% | PTCT | PTC THERAPEUTICS INC | -- | $132,053.52 | 2,901 | B17VCN9 |
| 0.30% | ACLX | ARCELLX INC | -- | $131,789.41 | 2,021 | BPCJ1Q2 |
| 0.29% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $127,566.39 | 2,757 | BGMGM89 |
| 0.27% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $120,840.53 | 3,403 | BJ62Z18 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $118,407.15 | 3,155 | BDHF4K6 |
| 0.25% | ALVO | ALVOTECH SA | -- | $110,234.60 | 11,090 | BPNTJ34 |
| 0.24% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $106,092.18 | 3,483 | BFZQ0L8 |
| 0.24% | MRUS | MERUS NV | -- | $105,747.20 | 2,542 | BZBY005 |
| 0.23% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $103,664.78 | 2,258 | BDCBCD8 |
| 0.23% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $103,066.53 | 3,423 | BDD19F8 |
| 0.20% | IMVT | IMMUNOVANT INC | -- | $90,985.44 | 6,249 | BJRFSB7 |
| 0.20% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $87,295.25 | 3,005 | BMX9K07 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $85,859.84 | 2,816 | BRJ3GY4 |
| 0.18% | APLS | APELLIS PHARMACEUTICALS INC | -- | $82,090.26 | 4,617 | BYTQ6X1 |
| 0.18% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $81,980.38 | 11,402 | BFNF1D6 |
| 0.18% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $79,867.93 | 7,687 | 2100362 |
| 0.18% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $79,422.15 | 1,803 | BJDX8Y8 |
| 0.18% | VCYT | VERACYTE INC | -- | $78,555.80 | 2,867 | BFTWZY0 |
| 0.17% | VCEL | VERICEL CORP | -- | $76,056.44 | 1,838 | BSBMN89 |
| 0.17% | ZLAB | ZAI LAB LTD-ADR | -- | $74,782.50 | 2,301 | BD9GVY0 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $73,851.20 | 4,040 | BP8JSP4 |
| 0.16% | NVCR | NOVOCURE LTD | -- | $73,218.73 | 4,043 | BYSS4X4 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $72,971.72 | 5,342 | BD2B4V0 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $72,153.76 | 2,801 | BRBCSP4 |
| 0.16% | KYMR | KYMERA THERAPEUTICS INC | -- | $72,076.13 | 2,389 | BMPRZV5 |
| 0.16% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $72,014.30 | 2,110 | BKSGZN7 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $71,984.80 | 26,860 | BNSP0B8 |
| 0.16% | LGND | LIGAND PHARMACEUTICALS | -- | $71,713.32 | 708 | 2501578 |
| 0.16% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $71,394.21 | 4,639 | BYQBFJ8 |
| 0.16% | FOLD | AMICUS THERAPEUTICS INC | -- | $70,750.52 | 11,302 | B19FQ48 |
| 0.15% | APGE | APOGEE THERAPEUTICS INC | -- | $66,836.16 | 1,656 | BM9HHL5 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $65,778.12 | 2,053 | B72ZBG4 |
| 0.14% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $62,375.72 | 2,108 | BCBVTX1 |
| 0.14% | TWST | TWIST BIOSCIENCE CORP | -- | $61,783.04 | 2,194 | BGKG6G7 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $61,106.88 | 1,272 | BMGJZJ8 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $60,673.64 | 1,412 | BMH5RL1 |
| 0.14% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $60,239.29 | 14,533 | BM9FJ13 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $60,149.60 | 3,220 | BK0VHF6 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $59,612.24 | 4,364 | BKX9VD3 |
| 0.12% | JANX | JANUX THERAPEUTICS INC | -- | $54,806.54 | 2,174 | BMFX8Y7 |
| 0.12% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $54,032.80 | 2,192 | BQS9486 |
| 0.12% | BEAM | BEAM THERAPEUTICS INC | -- | $53,081.96 | 3,079 | BK6L288 |
| 0.12% | SPRY | ARS PHARMACEUTICALS INC | -- | $51,909.00 | 3,575 | BMCR7V2 |
| 0.12% | ETNB | 89BIO INC | -- | $51,820.50 | 5,370 | BK1K484 |
| 0.12% | TVTX | TRAVERE THERAPEUTICS INC | -- | $51,244.80 | 3,264 | BLFGJD5 |
| 0.12% | INDV | INDIVIOR PLC | -- | $51,196.07 | 4,567 | BP0BQQ5 |
| 0.11% | DYN | DYNE THERAPEUTICS INC | -- | $49,515.90 | 4,161 | BN15WD1 |
| 0.11% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $48,831.66 | 3,483 | BKY5JZ8 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $47,992.36 | 5,429 | BJ5FZ74 |
| 0.11% | GRAL | GRAIL INC | -- | $47,919.72 | 1,236 | BSLSSX7 |
| 0.11% | MNKD | MANNKIND CORP | -- | $47,128.96 | 11,168 | BF081J4 |
| 0.10% | VERA | VERA THERAPEUTICS INC | -- | $46,032.35 | 2,345 | BL55460 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $45,873.27 | 801 | BCDWBX6 |
| 0.10% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $45,504.18 | 1,458 | BLCD809 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $44,818.48 | 4,564 | BRJZSK0 |
| 0.10% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,371.14 | 1,702 | B3X26D8 |
| 0.10% | INVA | INNOVIVA INC | -- | $43,398.92 | 2,306 | BDDXF67 |
| 0.10% | NVAX | NOVAVAX INC | -- | $43,134.93 | 5,917 | BJDQXG4 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $42,809.80 | 1,769 | BNFWZS4 |
| 0.10% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $42,377.96 | 3,358 | BLB0YQ9 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $41,780.04 | 5,052 | BFWLC09 |
| 0.09% | OCUL | OCULAR THERAPEUTIX INC | -- | $41,724.35 | 5,783 | BNZB1X8 |
| 0.09% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $40,092.75 | 1,545 | BRXB0C0 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $36,465.00 | 4,488 | B8K7T65 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $36,023.68 | 3,808 | BYZM6C2 |
| 0.08% | ARDX | ARDELYX INC | -- | $34,721.28 | 8,768 | BN89V40 |
| 0.08% | GERN | GERON CORP | -- | $34,674.92 | 23,429 | 2370381 |
| 0.08% | CVAC | CUREVAC NV | -- | $34,332.48 | 8,253 | BN4RD42 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $34,170.99 | 5,611 | BYZG9R0 |
| 0.08% | TXG | 10X GENOMICS INC-CLASS A | -- | $34,006.28 | 3,982 | BKS3RS7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $33,943.40 | 3,140 | BN7Q7R7 |
| 0.08% | HROW | HARROW INC | -- | $33,719.40 | 1,310 | BHNDW86 |
| 0.08% | SYRE | SPYRE THERAPEUTICS INC | -- | $33,410.19 | 2,217 | BQBBDY8 |
| 0.08% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $33,373.56 | 1,158 | BX7RSN3 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $32,428.26 | 1,542 | BBC9WC7 |
| 0.07% | AVDL | AVADEL PHARMACEUTICALS | -- | $31,479.60 | 3,545 | BDGMC59 |
| 0.07% | QURE | UNIQURE NV | -- | $30,292.47 | 1,989 | BJFSR88 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $30,135.69 | 1,797 | BMFD115 |
| 0.07% | MLYS | MINERALYS THERAPEUTICS INC | -- | $29,914.56 | 1,833 | BP9N0G0 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $29,090.32 | 2,534 | BPCQZY9 |
| 0.06% | LENZ | LENZ THERAPEUTICS INC | -- | $28,558.64 | 1,012 | BQV0J03 |
| 0.06% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $28,426.02 | 742 | BQ721R4 |
| 0.06% | NRIX | NURIX THERAPEUTICS INC | -- | $27,892.08 | 2,792 | BMVLGP2 |
| 0.06% | CRMD | CORMEDIX INC | -- | $27,364.32 | 2,232 | BJ0LT31 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $26,761.92 | 5,484 | BLR7H87 |
| 0.06% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $25,728.32 | 3,922 | BDFKQ07 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $25,581.20 | 1,240 | BMGTLY5 |
| 0.06% | REPL | REPLIMUNE GROUP INC | -- | $24,817.08 | 2,833 | BDDVW37 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $23,999.43 | 3,129 | BYTYP72 |
| 0.05% | ANAB | ANAPTYSBIO INC | -- | $23,394.72 | 1,128 | BDRW1L7 |
| 0.05% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $23,374.56 | 3,728 | BLB0YH0 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $23,257.45 | 5,045 | BK4PZ38 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $22,446.62 | 6,971 | BZ0QMB7 |
| 0.05% | EOLS | EVOLUS INC | -- | $22,265.24 | 2,329 | BDRJH21 |
| 0.05% | ABCL | ABCELLERA BIOLOGICS INC | -- | $21,924.00 | 10,962 | BL53SR3 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $21,491.85 | 7,541 | BNC1BX1 |
| 0.05% | KROS | KEROS THERAPEUTICS INC | -- | $21,126.72 | 1,492 | BM7V485 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $21,106.75 | 12,061 | BF0DMK7 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $20,761.56 | 1,818 | BD06CS0 |
| 0.05% | COGT | COGENT BIOSCIENCES INC | -- | $20,730.60 | 4,188 | BLR6XK8 |
| 0.04% | XNCR | XENCOR INC | -- | $19,932.48 | 2,592 | BGCYWN8 |
| 0.04% | TRVI | TREVI THERAPEUTICS INC | -- | $19,820.61 | 3,287 | BJH9ZN0 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $19,074.86 | 2,698 | BPQYY97 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $18,539.04 | 2,971 | BYZD465 |
| 0.04% | STOK | STOKE THERAPEUTICS INC | -- | $18,506.00 | 1,948 | BJQ05Z6 |
| 0.04% | SVRA | SAVARA INC | -- | $18,497.09 | 6,313 | BYXGN81 |
| 0.04% | RGNX | REGENXBIO INC | -- | $17,974.78 | 1,823 | BZ0G875 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $17,846.99 | 1,861 | BMVNDH9 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $17,741.42 | 6,236 | BN2R582 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $17,218.96 | 748 | BL95N25 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $17,167.41 | 1,809 | BMNDK09 |
| 0.04% | ALMS | ALUMIS INC | -- | $17,041.64 | 3,521 | BPLQG36 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $16,979.28 | 2,152 | BM90J52 |
| 0.04% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $16,894.72 | 3,152 | BPCK358 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $16,822.91 | 1,963 | BLFBZ32 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $16,668.61 | 1,049 | BKLCWZ3 |
| 0.04% | SANA | SANA BIOTECHNOLOGY INC | -- | $16,426.00 | 8,213 | BMFJJ97 |
| 0.04% | ARVN | ARVINAS INC | -- | $16,369.10 | 2,530 | BDZ30Q0 |
| 0.04% | ALT | ALTIMMUNE INC | -- | $16,346.41 | 2,833 | BFY7DC4 |
| 0.03% | ORIC | ORIC PHARMACEUTICALS INC | -- | $15,547.35 | 2,613 | BKVDFF7 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $15,483.64 | 538 | B292NQ7 |
| 0.03% | ORKA | ORUKA THERAPEUTICS INC | -- | $15,408.63 | 1,377 | BKVF0J2 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $15,341.68 | 2,627 | 2107437 |
| 0.03% | HCM | HUTCHMED CHINA-ADR | -- | $15,141.07 | 1,141 | BYXV9H7 |
| 0.03% | PSNL | PERSONALIS INC | -- | $15,001.14 | 3,247 | BJQ0608 |
| 0.03% | PGEN | PRECIGEN INC | -- | $14,974.47 | 10,773 | BKM5C84 |
| 0.03% | RAPP | RAPPORT THERAPEUTICS INC | -- | $14,967.52 | 1,346 | BR3T9B6 |
| 0.03% | SAGE | SAGE THERAPEUTICS INC | -- | $14,951.82 | 2,262 | BP4GNK9 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $14,547.50 | 2,875 | BFYQFJ2 |
| 0.03% | TRML | TOURMALINE BIO INC | -- | $14,399.61 | 943 | BQ80NC6 |
| 0.03% | VERV | VERVE THERAPEUTICS INC | -- | $14,305.08 | 3,266 | BNKGXX2 |
| 0.03% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $14,091.96 | 2,731 | BMZ4LN0 |
| 0.03% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $14,061.60 | 2,511 | BMGS7L1 |
| 0.03% | FTRE | FORTREA HOLDINGS INC | -- | $13,992.00 | 3,300 | BRXYZ57 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $13,548.33 | 1,251 | BQS7491 |
| 0.03% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $13,122.00 | 1,620 | BKDQKM6 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $12,969.00 | 1,980 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $12,785.04 | 648 | BQD3J33 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $12,748.80 | 996 | BKC9SX3 |
| 0.03% | ERAS | ERASCA INC | -- | $12,584.00 | 10,400 | BNLYBF3 |
| 0.03% | TKNO | ALPHA TEKNOVA INC | -- | $12,217.03 | 1,961 | BP7L561 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $12,054.60 | 543 | BPBPCG8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,975.31 | 5,218 | BMCWKZ2 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $11,679.36 | 1,344 | BMWXFT4 |
| 0.03% | HUMA | HUMACYTE INC | -- | $11,359.20 | 4,733 | BMYTJP4 |
| 0.03% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,279.16 | 7,372 | BFMLGR4 |
| 0.03% | ABSI | ABSCI CORP | -- | $11,238.50 | 4,225 | BN94K69 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $10,917.72 | 1,838 | BP81R42 |
| 0.02% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $10,638.45 | 2,515 | BJLKVS6 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $10,538.46 | 1,383 | BP81RK8 |
| 0.02% | NGNE | NEUROGENE INC | -- | $9,849.84 | 546 | BS2F741 |
| 0.02% | CMPS | COMPASS PATHWAYS PLC | -- | $9,547.12 | 2,284 | BMC3HS7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $9,484.67 | 10,074 | B4N8MH9 |
| 0.02% | INZY | INOZYME PHARMA INC | -- | $9,357.48 | 2,363 | BMVLGY1 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $9,187.50 | 3,125 | BMDJ0C9 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $9,153.00 | 2,260 | BP7KZP7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,094.80 | 2,145 | B12W3P6 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $8,854.95 | 3,107 | BLN9Z50 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $8,798.46 | 13,331 | BWFZX59 |
| 0.02% | MXCT | MAXCYTE INC | -- | $8,730.00 | 3,880 | BKMQF66 |
| 0.02% | THRD | THIRD HARMONIC BIO INC | -- | $8,621.60 | 1,658 | BNNPQY8 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,550.58 | 935 | BQB9HM8 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,470.44 | 2,046 | BMF7DT9 |
| 0.02% | ATXS | ASTRIA THERAPEUTICS INC | -- | $8,470.08 | 2,076 | BMYRFN8 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,407.17 | 7,713 | BFZNYB7 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,373.20 | 1,730 | BL5B6Z1 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $8,203.08 | 2,364 | BYP80F1 |
| 0.02% | SLDB | SOLID BIOSCIENCES INC | -- | $8,112.23 | 2,807 | BQHN6C7 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $8,099.63 | 737 | BN72KB0 |
| 0.02% | ANNX | ANNEXON INC | -- | $8,077.26 | 3,921 | BMVV9R5 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $8,061.21 | 2,083 | BMFK3H6 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $7,919.97 | 6,439 | BPG5P75 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $7,680.66 | 3,354 | BYVQJ96 |
| 0.02% | CDXS | CODEXIS INC | -- | $7,495.62 | 3,047 | B5LL2C2 |
| 0.02% | TNGX | TANGO THERAPEUTICS INC | -- | $7,417.11 | 3,977 | BP2P6L0 |
| 0.02% | CRGX | CARGO THERAPEUTICS INC | -- | $6,941.30 | 1,693 | BQHN2F2 |
| 0.02% | OMER | OMEROS CORP | -- | $6,865.04 | 2,132 | B4NB858 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $6,806.24 | 1,648 | BG31GH0 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $6,683.82 | 533 | BNSP8K3 |
| 0.01% | SCPH | SCPHARMACEUTICALS INC | -- | $6,452.71 | 1,841 | BYX2Z16 |
| 0.01% | URGN | UROGEN PHARMA LTD | -- | $6,332.16 | 1,552 | BZ7PJQ1 |
| 0.01% | OABI | OMNIAB INC | -- | $6,277.32 | 4,452 | BN13S71 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $6,166.41 | 3,638 | BZC0D70 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $6,130.80 | 1,703 | BKLXFX5 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,006.91 | 2,009 | BY7RB53 |
| 0.01% | PRME | PRIME MEDICINE INC | -- | $5,934.75 | 4,825 | BPBJFM7 |
| 0.01% | ESPR | ESPERION THERAPEUTICS INC | -- | $5,820.14 | 7,248 | BBNBTD2 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $5,028.00 | 4,190 | BCZS820 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $4,919.94 | 3,037 | BZ8FPH3 |
| 0.01% | ALEC | ALECTOR INC | -- | $4,774.95 | 3,645 | BJ4LDC4 |
| 0.01% | NKTX | NKARTA INC | -- | $4,581.94 | 2,596 | BK80YJ8 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $4,539.53 | 10,747 | BN6MB18 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $4,529.71 | 2,347 | BMXNGZ6 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $4,513.75 | 785 | B9L5200 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $4,265.89 | 5,943 | BN4JN37 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $3,922.36 | 1,588 | BSMLR16 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $3,745.28 | 1,216 | BQ6C357 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $3,650.53 | 5,887 | B3MZ6K5 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,648.22 | 2,309 | BFDV8K0 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $3,577.07 | 2,611 | BKX9NQ0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,000.26 | 2,239 | BMDWW66 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $2,967.60 | 2,473 | BMW5LX6 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,737.59 | 3,033 | BF12XC2 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $2,625.60 | 2,188 | BLBR8D5 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $2,600.64 | 1,806 | BNLYBJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $1,932.85 | 1,333 | BNKF6N0 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,772.16 | 4,544 | BF3NP05 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $1,770.12 | 894 | BMF1LJ7 |
| -- | PEPG | PEPGEN INC | -- | $1,768.41 | 1,203 | BMTX3D7 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $1,754.80 | 4,280 | BJL38Z1 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $1,504.80 | 1,254 | BKS3SM8 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,316.75 | 1,145 | BP2TPK4 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $999.75 | 465 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $739.20 | 448 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 35.47% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 15,767,607 | -- | 3,863 | -- |
| 29.79% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 13,245,117 | -- | 3,245 | -- |
| 17.62% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 7,832,782 | -- | 1,919 | -- |
| 17.12% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 7,612,371 | -- | 1,865 | -- |
| 14.10% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 6,269,491 | -- | 1,536 | -- |
| 12.70% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 5,644,991 | -- | 1,383 | -- |
| -- | -- | TREASURY BILL | -- | $7,496,510.85 | 7,500,000 | BQC9631 |
| -- | -- | TREASURY BILL | -- | $6,979,574.84 | 7,000,000 | BSNQ2D7 |
| -- | -- | TREASURY BILL | -- | $4,485,280.77 | 4,500,000 | BRBYPQ0 |
| -- | -- | TREASURY BILL | -- | $1,494,411.84 | 1,500,000 | BQ7YG75 |
| -- | -- | TREASURY BILL | -- | $747,021.64 | 750,000 | BS60BF1 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $-9,525,408.70 | -9,525,409 | -- |
Index
as of 3/31/2025
- Total Number of Companies264
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.80 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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