BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 4/30/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -1.49% | -14.47% | -20.30% | -6.07% | -4.31% | -1.10% | -4.38% | -4.22% | 13.18% | 04/07/2010 |
| BIB NAV | -1.28% | -14.31% | -20.40% | -5.95% | -4.14% | -1.07% | -4.38% | -4.22% | 13.19% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -12.17% | -4.65% | -23.66% | -4.65% | -14.82% | -7.50% | 1.19% | -4.67% | 13.38% | 04/07/2010 |
| BIB NAV | -12.25% | -4.72% | -23.81% | -4.72% | -14.95% | -7.45% | 1.07% | -4.69% | 13.36% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 6/05/2025- NAV $45.16
- NAV Change $-0.05
- Market Price $45.21
- Market Price Change $-0.04
- Trading Volume (M) 12,598
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 6/05/2025- NAV $45.16
- NAV Change $-0.05
- Market Price $45.21
- Market Price Change $-0.04
- Trading Volume (M) 12,598
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2025
Holdings
as of 6/05/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.13% | GILD | GILEAD SCIENCES INC | -- | $2,850,530.76 | 25,806 | 2369174 |
| 5.91% | AMGN | AMGEN INC | -- | $2,749,269.60 | 9,576 | 2023607 |
| 5.87% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,728,605.36 | 6,148 | 2931034 |
| 4.11% | REGN | REGENERON PHARMACEUTICALS | -- | $1,910,541.85 | 3,955 | 2730190 |
| 3.33% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,549,809.35 | 21,421 | 2989044 |
| 3.15% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,466,696.00 | 4,762 | B00FWN1 |
| 1.51% | BIIB | BIOGEN INC | -- | $701,988.60 | 5,385 | 2455965 |
| 1.47% | ARGX | ARGENX SE - ADR | -- | $683,935.02 | 1,178 | BDVLM39 |
| 1.16% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $537,975.00 | 15,940 | BMVP7Y0 |
| 1.15% | SMMT | SUMMIT THERAPEUTICS INC | -- | $535,393.28 | 27,136 | BMTVQS7 |
| 1.14% | UTHR | UNITED THERAPEUTICS CORP | -- | $528,160.92 | 1,652 | 2430412 |
| 1.13% | SNY | SANOFI-ADR | -- | $525,963.20 | 10,570 | 2964557 |
| 1.04% | INSM | INSMED INC | -- | $484,302.92 | 6,658 | 2614487 |
| 1.03% | ILMN | ILLUMINA INC | -- | $479,270.75 | 5,827 | 2613990 |
| 1.03% | INCY | INCYTE CORP | -- | $478,681.56 | 7,119 | 2471950 |
| 0.98% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $457,069.48 | 3,668 | 2623911 |
| 0.94% | EXEL | EXELIXIS INC | -- | $436,241.52 | 10,296 | 2576941 |
| 0.87% | BNTX | BIONTECH SE-ADR | -- | $403,149.00 | 3,660 | BK6H543 |
| 0.85% | ONC | BEONE MEDICINES LTD-ADR | -- | $395,523.00 | 1,539 | BYYWPW6 |
| 0.85% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $394,516.10 | 2,222 | BV9G6B8 |
| 0.83% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $387,884.86 | 7,018 | 2437071 |
| 0.80% | VTRS | VIATRIS INC | -- | $371,487.06 | 43,911 | BMWS3X9 |
| 0.80% | MRNA | MODERNA INC | -- | $370,721.16 | 14,193 | BGSXTS3 |
| 0.78% | TEM | TEMPUS AI INC | -- | $360,700.34 | 6,149 | BSLSJJ0 |
| 0.71% | MEDP | MEDPACE HOLDINGS INC | -- | $329,103.18 | 1,121 | BDCBC61 |
| 0.65% | BPMC | BLUEPRINT MEDICINES CORP | -- | $300,692.90 | 2,351 | BWY52P3 |
| 0.63% | ROIV | ROIVANT SCIENCES LTD | -- | $293,988.80 | 26,249 | BMW4NZ9 |
| 0.59% | RVMD | REVOLUTION MEDICINES INC | -- | $274,927.80 | 6,839 | BL71K91 |
| 0.58% | BBIO | BRIDGEBIO PHARMA INC | -- | $268,226.64 | 6,996 | BK1KWG8 |
| 0.53% | VRNA | VERONA PHARMA PLC - ADR | -- | $247,980.46 | 2,899 | BYWPZK5 |
| 0.52% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $243,059.20 | 2,234 | B4Q5ZN4 |
| 0.52% | HALO | HALOZYME THERAPEUTICS INC | -- | $242,581.50 | 4,530 | 2975098 |
| 0.48% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $222,569.20 | 812 | BD59BS7 |
| 0.47% | GH | GUARDANT HEALTH INC | -- | $219,781.40 | 4,540 | BFXC911 |
| 0.44% | IONS | IONIS PHARMACEUTICALS INC | -- | $206,083.52 | 5,848 | BDJ0LS6 |
| 0.43% | AXSM | AXSOME THERAPEUTICS INC | -- | $198,524.04 | 1,794 | BYZR4X4 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $190,071.06 | 2,434 | BMVBZD3 |
| 0.40% | ALKS | ALKERMES PLC | -- | $185,442.00 | 5,982 | B3P6D26 |
| 0.37% | ADMA | ADMA BIOLOGICS INC | -- | $173,398.24 | 8,696 | B9NSBM2 |
| 0.35% | PCVX | VAXCYTE INC | -- | $164,847.60 | 4,737 | BKPVGH6 |
| 0.34% | AKRO | AKERO THERAPEUTICS INC | -- | $157,990.26 | 2,929 | BK7Y2V9 |
| 0.34% | RNA | AVIDITY BIOSCIENCES INC | -- | $157,378.98 | 4,422 | BMWHPY1 |
| 0.33% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $153,934.68 | 2,326 | BF2YWG4 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $150,068.73 | 2,901 | B17VCN9 |
| 0.31% | MRUS | MERUS NV | -- | $142,377.42 | 2,542 | BZBY005 |
| 0.30% | KRYS | KRYSTAL BIOTECH INC | -- | $140,577.20 | 1,060 | BD6JX35 |
| 0.30% | SRPT | SAREPTA THERAPEUTICS INC | -- | $139,940.49 | 3,569 | B8DPDT7 |
| 0.30% | CYTK | CYTOKINETICS INC | -- | $139,740.48 | 4,356 | BBBSBJ5 |
| 0.29% | ACLX | ARCELLX INC | -- | $133,891.25 | 2,021 | BPCJ1Q2 |
| 0.28% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $130,920.90 | 6,135 | 2713317 |
| 0.28% | SWTX | SPRINGWORKS THERAPEUTICS INC | -- | $129,027.60 | 2,757 | BGMGM89 |
| 0.27% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $125,604.73 | 3,403 | BJ62Z18 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $121,688.35 | 3,155 | BDHF4K6 |
| 0.26% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $121,525.56 | 2,258 | BDCBCD8 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $119,292.75 | 3,483 | BFZQ0L8 |
| 0.25% | ALVO | ALVOTECH SA | -- | $116,445.00 | 11,090 | BPNTJ34 |
| 0.24% | KYMR | KYMERA THERAPEUTICS INC | -- | $113,859.74 | 2,389 | BMPRZV5 |
| 0.24% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $110,631.36 | 3,423 | BDD19F8 |
| 0.22% | IMVT | IMMUNOVANT INC | -- | $100,108.98 | 6,249 | BJRFSB7 |
| 0.20% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $94,597.40 | 3,005 | BMX9K07 |
| 0.19% | APLS | APELLIS PHARMACEUTICALS INC | -- | $88,184.70 | 4,617 | BYTQ6X1 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $86,535.68 | 2,816 | BRJ3GY4 |
| 0.18% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $84,403.26 | 7,687 | 2100362 |
| 0.18% | ZLAB | ZAI LAB LTD-ADR | -- | $84,078.54 | 2,301 | BD9GVY0 |
| 0.18% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $81,752.34 | 11,402 | BFNF1D6 |
| 0.17% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $80,503.95 | 1,803 | BJDX8Y8 |
| 0.17% | VCEL | VERICEL CORP | -- | $79,769.20 | 1,838 | BSBMN89 |
| 0.17% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $78,820.40 | 4,040 | BP8JSP4 |
| 0.17% | IBRX | IMMUNITYBIO INC | -- | $77,894.00 | 26,860 | BNSP0B8 |
| 0.17% | VCYT | VERACYTE INC | -- | $77,351.66 | 2,867 | BFTWZY0 |
| 0.16% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $76,357.94 | 4,639 | BYQBFJ8 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $75,963.24 | 5,342 | BD2B4V0 |
| 0.16% | CGON | CG ONCOLOGY INC | -- | $74,590.63 | 2,801 | BRBCSP4 |
| 0.16% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,913.30 | 2,110 | BKSGZN7 |
| 0.16% | LGND | LIGAND PHARMACEUTICALS | -- | $73,759.44 | 708 | 2501578 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $71,827.35 | 2,345 | BL55460 |
| 0.15% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $70,786.64 | 2,108 | BCBVTX1 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $67,942.00 | 3,220 | BK0VHF6 |
| 0.14% | FOLD | AMICUS THERAPEUTICS INC | -- | $67,359.92 | 11,302 | B19FQ48 |
| 0.14% | TWST | TWIST BIOSCIENCE CORP | -- | $66,544.02 | 2,194 | BGKG6G7 |
| 0.14% | NVCR | NOVOCURE LTD | -- | $66,507.35 | 4,043 | BYSS4X4 |
| 0.14% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $66,415.81 | 14,533 | BM9FJ13 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $66,394.02 | 2,053 | B72ZBG4 |
| 0.13% | APGE | APOGEE THERAPEUTICS INC | -- | $62,348.40 | 1,656 | BM9HHL5 |
| 0.13% | TARS | TARSUS PHARMACEUTICALS INC | -- | $62,240.96 | 1,412 | BMH5RL1 |
| 0.13% | INDV | INDIVIOR PLC | -- | $62,065.53 | 4,567 | BP0BQQ5 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $61,068.72 | 1,272 | BMGJZJ8 |
| 0.13% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $58,957.64 | 4,364 | BKX9VD3 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $58,212.39 | 4,161 | BN15WD1 |
| 0.12% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $55,433.16 | 1,458 | BLCD809 |
| 0.12% | JANX | JANUX THERAPEUTICS INC | -- | $53,828.24 | 2,174 | BMFX8Y7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $53,584.23 | 5,429 | BJ5FZ74 |
| 0.11% | ETNB | 89BIO INC | -- | $53,485.20 | 5,370 | BK1K484 |
| 0.11% | BEAM | BEAM THERAPEUTICS INC | -- | $52,343.00 | 3,079 | BK6L288 |
| 0.11% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $51,618.06 | 3,483 | BKY5JZ8 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $48,924.18 | 5,783 | BNZB1X8 |
| 0.10% | INVA | INNOVIVA INC | -- | $48,818.02 | 2,306 | BDDXF67 |
| 0.10% | GRAL | GRAIL INC | -- | $48,809.64 | 1,236 | BSLSSX7 |
| 0.10% | SPRY | ARS PHARMACEUTICALS INC | -- | $48,048.00 | 3,575 | BMCR7V2 |
| 0.10% | TVTX | TRAVERE THERAPEUTICS INC | -- | $48,046.08 | 3,264 | BLFGJD5 |
| 0.10% | MNKD | MANNKIND CORP | -- | $48,022.40 | 11,168 | BF081J4 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $47,963.88 | 801 | BCDWBX6 |
| 0.10% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $47,062.24 | 2,192 | BQS9486 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $45,608.40 | 1,545 | BRXB0C0 |
| 0.10% | PCRX | PACIRA BIOSCIENCES INC | -- | $45,511.48 | 1,702 | B3X26D8 |
| 0.10% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $45,411.80 | 4,564 | BRJZSK0 |
| 0.10% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $45,144.88 | 1,769 | BNFWZS4 |
| 0.09% | NVAX | NOVAVAX INC | -- | $41,359.83 | 5,917 | BJDQXG4 |
| 0.09% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $40,870.68 | 5,052 | BFWLC09 |
| 0.09% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $39,825.88 | 3,358 | BLB0YQ9 |
| 0.08% | GRFS | GRIFOLS SA-ADR | -- | $39,135.36 | 4,488 | B8K7T65 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $38,401.89 | 1,797 | BMFD115 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $37,874.25 | 5,611 | BYZG9R0 |
| 0.08% | HROW | HARROW INC | -- | $37,623.20 | 1,310 | BHNDW86 |
| 0.08% | SYRE | SPYRE THERAPEUTICS INC | -- | $36,846.54 | 2,217 | BQBBDY8 |
| 0.08% | CVAC | CUREVAC NV | -- | $36,808.38 | 8,253 | BN4RD42 |
| 0.08% | GERN | GERON CORP | -- | $36,549.24 | 23,429 | 2370381 |
| 0.08% | TXG | 10X GENOMICS INC-CLASS A | -- | $36,276.02 | 3,982 | BKS3RS7 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $35,042.40 | 3,140 | BN7Q7R7 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $34,900.00 | 2,792 | BMVLGP2 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $34,161.00 | 1,158 | BX7RSN3 |
| 0.07% | GMAB | GENMAB A/S -SP ADR | -- | $33,631.02 | 1,542 | BBC9WC7 |
| 0.07% | AVDL | AVADEL PHARMACEUTICALS | -- | $33,464.80 | 3,545 | BDGMC59 |
| 0.07% | QURE | UNIQURE NV | -- | $33,037.29 | 1,989 | BJFSR88 |
| 0.07% | ARDX | ARDELYX INC | -- | $31,915.52 | 8,768 | BN89V40 |
| 0.07% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $31,356.92 | 742 | BQ721R4 |
| 0.07% | ZYME | ZYMEWORKS INC | -- | $30,737.42 | 2,534 | BPCQZY9 |
| 0.07% | LENZ | LENZ THERAPEUTICS INC | -- | $30,663.60 | 1,012 | BQV0J03 |
| 0.06% | CRMD | CORMEDIX INC | -- | $29,417.76 | 2,232 | BJ0LT31 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $29,102.80 | 1,240 | BMGTLY5 |
| 0.06% | NTLA | INTELLIA THERAPEUTICS INC | -- | $28,864.64 | 3,808 | BYZM6C2 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $28,631.46 | 1,833 | BP9N0G0 |
| 0.06% | REPL | REPLIMUNE GROUP INC | -- | $27,621.75 | 2,833 | BDDVW37 |
| 0.06% | VIR | VIR BIOTECHNOLOGY INC | -- | $25,981.75 | 5,045 | BK4PZ38 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $25,979.94 | 10,962 | BL53SR3 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $25,909.60 | 3,728 | BLB0YH0 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $25,088.40 | 1,818 | BD06CS0 |
| 0.05% | COGT | COGENT BIOSCIENCES INC | -- | $25,086.12 | 4,188 | BLR6XK8 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $24,458.64 | 5,484 | BLR7H87 |
| 0.05% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $24,343.62 | 3,129 | BYTYP72 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $23,935.08 | 2,613 | BKVDFF7 |
| 0.05% | ANAB | ANAPTYSBIO INC | -- | $23,845.92 | 1,128 | BDRW1L7 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $23,701.40 | 6,971 | BZ0QMB7 |
| 0.05% | XNCR | XENCOR INC | -- | $23,639.04 | 2,592 | BGCYWN8 |
| 0.05% | EOLS | EVOLUS INC | -- | $22,684.46 | 2,329 | BDRJH21 |
| 0.05% | KROS | KEROS THERAPEUTICS INC | -- | $22,544.12 | 1,492 | BM7V485 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $22,154.38 | 3,287 | BJH9ZN0 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $21,718.08 | 7,541 | BNC1BX1 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $21,709.80 | 12,061 | BF0DMK7 |
| 0.05% | STOK | STOKE THERAPEUTICS INC | -- | $21,194.24 | 1,948 | BJQ05Z6 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $20,943.15 | 8,213 | BMFJJ97 |
| 0.04% | MNMD | MIND MEDICINE MINDMED INC | -- | $20,747.62 | 2,698 | BPQYY97 |
| 0.04% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $20,715.75 | 2,511 | BMGS7L1 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $20,204.64 | 6,236 | BN2R582 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $19,519.47 | 2,971 | BYZD465 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $19,482.93 | 1,809 | BMNDK09 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $18,926.37 | 1,861 | BMVNDH9 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $18,808.48 | 2,152 | BM90J52 |
| 0.04% | VERV | VERVE THERAPEUTICS INC | -- | $18,714.18 | 3,266 | BNKGXX2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $17,869.72 | 748 | BL95N25 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $17,853.98 | 1,049 | BKLCWZ3 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $17,813.27 | 943 | BQ80NC6 |
| 0.04% | ARVN | ARVINAS INC | -- | $17,507.60 | 2,530 | BDZ30Q0 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $17,411.66 | 1,141 | BYXV9H7 |
| 0.04% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $17,333.29 | 1,963 | BLFBZ32 |
| 0.04% | FTRE | FORTREA HOLDINGS INC | -- | $16,896.00 | 3,300 | BRXYZ57 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $16,785.63 | 1,377 | BKVF0J2 |
| 0.04% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $16,660.72 | 7,372 | BFMLGR4 |
| 0.04% | RAPP | RAPPORT THERAPEUTICS INC | -- | $16,596.18 | 1,346 | BR3T9B6 |
| 0.04% | PSNL | PERSONALIS INC | -- | $16,429.82 | 3,247 | BJQ0608 |
| 0.04% | ERAS | ERASCA INC | -- | $16,328.00 | 10,400 | BNLYBF3 |
| 0.03% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $15,917.60 | 3,152 | BPCK358 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $15,755.00 | 2,875 | BFYQFJ2 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $15,468.18 | 2,833 | BFY7DC4 |
| 0.03% | SIGA | SIGA TECHNOLOGIES INC | -- | $15,446.76 | 2,627 | 2107437 |
| 0.03% | SAGE | SAGE THERAPEUTICS INC | -- | $15,336.36 | 2,262 | BP4GNK9 |
| 0.03% | RGNX | REGENXBIO INC | -- | $15,240.28 | 1,823 | BZ0G875 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $15,042.48 | 538 | B292NQ7 |
| 0.03% | SVRA | SAVARA INC | -- | $15,024.94 | 6,313 | BYXGN81 |
| 0.03% | MESO | MESOBLAST LTD- SPON ADR | -- | $14,524.11 | 1,251 | BQS7491 |
| 0.03% | PGEN | PRECIGEN INC | -- | $14,328.09 | 10,773 | BKM5C84 |
| 0.03% | TNGX | TANGO THERAPEUTICS INC | -- | $13,959.27 | 3,977 | BP2P6L0 |
| 0.03% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $13,770.00 | 1,620 | BKDQKM6 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $13,681.92 | 1,344 | BMWXFT4 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $13,588.56 | 648 | BQD3J33 |
| 0.03% | NGNE | NEUROGENE INC | -- | $12,514.32 | 546 | BS2F741 |
| 0.03% | HUMA | HUMACYTE INC | -- | $12,400.46 | 4,733 | BMYTJP4 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $12,190.35 | 543 | BPBPCG8 |
| 0.03% | ABSI | ABSCI CORP | -- | $11,999.00 | 4,225 | BN94K69 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $11,973.78 | 3,354 | BYVQJ96 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $11,929.75 | 2,807 | BQHN6C7 |
| 0.03% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $11,862.36 | 996 | BKC9SX3 |
| 0.03% | ALMS | ALUMIS INC | -- | $11,795.35 | 3,521 | BPLQG36 |
| 0.03% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $11,795.35 | 2,515 | BJLKVS6 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $11,497.51 | 2,731 | BMZ4LN0 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,323.06 | 5,218 | BMCWKZ2 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $11,314.97 | 1,961 | BP7L561 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $11,229.96 | 1,383 | BP81RK8 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $11,211.80 | 1,838 | BP81R42 |
| 0.02% | TERN | TERNS PHARMACEUTICALS INC | -- | $11,062.50 | 3,125 | BMDJ0C9 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $10,863.94 | 3,922 | BDFKQ07 |
| 0.02% | ATXS | ASTRIA THERAPEUTICS INC | -- | $10,836.72 | 2,076 | BMYRFN8 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $10,441.20 | 2,260 | BP7KZP7 |
| 0.02% | CMPS | COMPASS PATHWAYS PLC | -- | $10,346.52 | 2,284 | BMC3HS7 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $10,074.00 | 10,074 | B4N8MH9 |
| 0.02% | PRTA | PROTHENA CORP PLC | -- | $10,018.80 | 1,980 | B91XRN2 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,998.55 | 3,921 | BMVV9R5 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $9,949.77 | 7,713 | BFZNYB7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $9,911.33 | 3,107 | BLN9Z50 |
| 0.02% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $9,558.33 | 13,331 | BWFZX59 |
| 0.02% | INZY | INOZYME PHARMA INC | -- | $9,428.37 | 2,363 | BMVLGY1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,416.55 | 2,145 | B12W3P6 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $9,359.30 | 1,730 | BL5B6Z1 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $9,243.24 | 2,364 | BYP80F1 |
| 0.02% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $9,078.99 | 6,439 | BPG5P75 |
| 0.02% | THRD | THIRD HARMONIC BIO INC | -- | $8,770.82 | 1,658 | BNNPQY8 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $8,733.45 | 737 | BN72KB0 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $8,732.90 | 935 | BQB9HM8 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $8,429.52 | 2,046 | BMF7DT9 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $8,407.68 | 7,248 | BBNBTD2 |
| 0.02% | YMAB | Y-MABS THERAPEUTICS INC | -- | $8,404.80 | 1,648 | BG31GH0 |
| 0.02% | MXCT | MAXCYTE INC | -- | $8,342.00 | 3,880 | BKMQF66 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $8,332.00 | 2,083 | BMFK3H6 |
| 0.02% | URGN | UROGEN PHARMA LTD | -- | $7,977.28 | 1,552 | BZ7PJQ1 |
| 0.02% | CRGX | CARGO THERAPEUTICS INC | -- | $7,720.08 | 1,693 | BQHN2F2 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $7,566.51 | 1,841 | BYX2Z16 |
| 0.02% | OMER | OMEROS CORP | -- | $7,035.60 | 2,132 | B4NB858 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,886.22 | 3,047 | B5LL2C2 |
| 0.01% | INBX | INHIBRX BIOSCIENCES INC | -- | $6,870.37 | 533 | BNSP8K3 |
| 0.01% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $6,658.73 | 1,703 | BKLXFX5 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,629.70 | 2,009 | BY7RB53 |
| 0.01% | PRME | PRIME MEDICINE INC | -- | $6,562.00 | 4,825 | BPBJFM7 |
| 0.01% | ACIU | AC IMMUNE SA | -- | $6,293.74 | 3,638 | BZC0D70 |
| 0.01% | -- | LYELL IMMUNOPHARMA INC COMMON STOCK USD 0.0001 | -- | $6,154.02 | 537 | -- |
| 0.01% | OABI | OMNIAB INC | -- | $6,143.76 | 4,452 | BN13S71 |
| 0.01% | LRMR | LARIMAR THERAPEUTICS INC | -- | $5,773.62 | 2,347 | BMXNGZ6 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,659.85 | 785 | B9L5200 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $5,614.60 | 4,190 | BCZS820 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $5,466.60 | 3,037 | BZ8FPH3 |
| 0.01% | ALEC | ALECTOR INC | -- | $5,139.45 | 3,645 | BJ4LDC4 |
| 0.01% | NMRA | NEUMORA THERAPEUTICS INC | -- | $4,814.42 | 5,943 | BN4JN37 |
| 0.01% | NKTX | NKARTA INC | -- | $4,750.68 | 2,596 | BK80YJ8 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $4,668.72 | 1,588 | BSMLR16 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $3,976.32 | 1,216 | BQ6C357 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $3,838.17 | 2,611 | BKX9NQ0 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,604.79 | 2,239 | BMDWW66 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $3,361.48 | 5,887 | B3MZ6K5 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,348.05 | 2,309 | BFDV8K0 |
| 0.01% | BMEA | BIOMEA FUSION INC | -- | $3,265.85 | 1,333 | BNKF6N0 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $3,066.52 | 2,473 | BMW5LX6 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,034.08 | 1,806 | BNLYBJ7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $2,713.12 | 2,188 | BLBR8D5 |
| 0.01% | STRO | SUTRO BIOPHARMA INC | -- | $2,500.10 | 3,033 | BF12XC2 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $1,752.24 | 894 | BMF1LJ7 |
| -- | PEPG | PEPGEN INC | -- | $1,708.26 | 1,203 | BMTX3D7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,673.56 | 4,544 | BF3NP05 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $1,557.06 | 4,280 | BJL38Z1 |
| -- | IGMS | IGM BIOSCIENCES INC | -- | $1,554.96 | 1,254 | BKS3SM8 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,431.25 | 1,145 | BP2TPK4 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $1,329.90 | 465 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $824.32 | 448 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 34.73% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 16,153,791 | -- | 3,863 | -- |
| 27.93% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 12,992,449 | -- | 3,107 | -- |
| 18.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 8,488,790 | -- | 2,030 | -- |
| 17.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 8,024,625 | -- | 1,919 | -- |
| 15.96% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 7,422,464 | -- | 1,775 | -- |
| 13.81% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 6,423,045 | -- | 1,536 | -- |
| -- | -- | TREASURY BILL | -- | $6,991,094.39 | 7,000,000 | BSNQ2D7 |
| -- | -- | TREASURY BILL | -- | $4,492,697.85 | 4,500,000 | BRBYPQ0 |
| -- | -- | UNITED STATES OF AMERICA BILL ZERO CPN 08/JUL/2025 USD 100 | -- | $3,985,191.12 | 4,000,000 | -- |
| -- | -- | TREASURY BILL | -- | $1,496,864.25 | 1,500,000 | BQ7YG75 |
| -- | -- | TREASURY BILL | -- | $748,261.00 | 750,000 | BS60BF1 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $-4,791,491.49 | -4,791,491 | -- |
Index
as of 3/31/2025
- Total Number of Companies264
- Price/Earnings Ratio--
- Price/Book Ratio4.157
- Dividend Yield ( % )0.88
- Avg. Index Market Capitalization$5.80 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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