BIB
Ultra Nasdaq Biotechnology
Investment Objective
ProShares Ultra Nasdaq Biotechnology seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Fund detail sections
Common uses for magnified exposure
Documents & Downloads
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 7/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 10.19% | 6.76% | -8.68% | 0.27% | -23.18% | -0.36% | -5.86% | -6.05% | 13.44% | 04/07/2010 |
| BIB NAV | 10.39% | 6.81% | -8.47% | 0.46% | -23.08% | -0.27% | -5.82% | -6.03% | 13.44% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | 6.88% | -4.57% | -9.00% | -9.00% | -21.42% | -1.05% | -8.38% | -6.36% | 12.80% | 04/07/2010 |
| BIB NAV | 6.82% | -4.48% | -9.00% | -9.00% | -21.46% | -1.12% | -8.40% | -6.35% | 12.79% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.14%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/11/2025- NAV $50.61
- NAV Change $-0.21
- Market Price $50.58
- Market Price Change $-0.22
- Trading Volume (M) 7,676
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Expense Ratio 0.95%
- Gross Expense Ratio 1.14%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 8/11/2025- NAV $50.61
- NAV Change $-0.21
- Market Price $50.58
- Market Price Change $-0.22
- Trading Volume (M) 7,676
- 30-Day Median Bid Ask Spread 0.28%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 6/30/2025
Holdings
as of 8/11/2025
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 5.54% | GILD | GILEAD SCIENCES INC | -- | $2,832,852.05 | 23,515 | 2369174 |
| 5.01% | AMGN | AMGEN INC | -- | $2,560,678.38 | 8,982 | 2023607 |
| 4.29% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $2,192,837.76 | 5,856 | 2931034 |
| 4.20% | REGN | REGENERON PHARMACEUTICALS | -- | $2,148,819.84 | 3,936 | 2730190 |
| 3.62% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,848,750.00 | 4,250 | B00FWN1 |
| 3.20% | AZN | ASTRAZENECA PLC-SPONS ADR | -- | $1,636,798.86 | 22,098 | 2989044 |
| 1.54% | SMMT | SUMMIT THERAPEUTICS INC | -- | $784,954.50 | 27,786 | BMTVQS7 |
| 1.50% | INSM | INSMED INC | -- | $769,345.35 | 6,815 | 2614487 |
| 1.47% | ARGX | ARGENX SE - ADR | -- | $753,902.00 | 1,180 | BDVLM39 |
| 1.37% | BIIB | BIOGEN INC | -- | $701,696.00 | 5,482 | 2455965 |
| 1.12% | INCY | INCYTE CORP | -- | $573,493.98 | 7,242 | 2471950 |
| 1.12% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $570,535.35 | 15,765 | BMVP7Y0 |
| 1.10% | ILMN | ILLUMINA INC | -- | $561,381.94 | 5,923 | 2613990 |
| 0.99% | UTHR | UNITED THERAPEUTICS CORP | -- | $507,125.84 | 1,688 | 2430412 |
| 0.97% | SNY | SANOFI-ADR | -- | $496,979.67 | 10,527 | 2964557 |
| 0.95% | MEDP | MEDPACE HOLDINGS INC | -- | $483,502.75 | 1,075 | BDCBC61 |
| 0.90% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $459,097.94 | 3,703 | 2623911 |
| 0.88% | ONC | BEONE MEDICINES LTD-ADR | -- | $447,663.75 | 1,545 | BYYWPW6 |
| 0.87% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $444,851.90 | 2,270 | BV9G6B8 |
| 0.85% | VTRS | VIATRIS INC | -- | $432,972.32 | 43,912 | BMWS3X9 |
| 0.80% | BNTX | BIONTECH SE-ADR | -- | $408,413.88 | 3,738 | BK6H543 |
| 0.80% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $407,540.00 | 7,175 | 2437071 |
| 0.75% | TEM | TEMPUS AI INC | -- | $382,436.16 | 6,288 | BSLSJJ0 |
| 0.75% | EXEL | EXELIXIS INC | -- | $381,582.00 | 10,200 | 2576941 |
| 0.72% | MRNA | MODERNA INC | -- | $368,525.43 | 14,469 | BGSXTS3 |
| 0.67% | BBIO | BRIDGEBIO PHARMA INC | -- | $342,696.96 | 7,104 | BK1KWG8 |
| 0.61% | VRNA | VERONA PHARMA PLC - ADR | -- | $309,721.32 | 2,943 | BYWPZK5 |
| 0.57% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $290,434.50 | 831 | BD59BS7 |
| 0.57% | HALO | HALOZYME THERAPEUTICS INC | -- | $289,922.90 | 4,610 | 2975098 |
| 0.56% | ROIV | ROIVANT SCIENCES LTD | -- | $284,097.78 | 25,434 | BMW4NZ9 |
| 0.50% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $255,500.25 | 2,307 | B4Q5ZN4 |
| 0.50% | GH | GUARDANT HEALTH INC | -- | $253,998.00 | 4,635 | BFXC911 |
| 0.48% | IONS | IONIS PHARMACEUTICALS INC | -- | $243,202.20 | 5,955 | BDJ0LS6 |
| 0.47% | RVMD | REVOLUTION MEDICINES INC | -- | $241,824.30 | 6,969 | BL71K91 |
| 0.44% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $224,457.80 | 2,380 | BF2YWG4 |
| 0.40% | RNA | AVIDITY BIOSCIENCES INC | -- | $206,467.80 | 4,510 | BMWHPY1 |
| 0.37% | AXSM | AXSOME THERAPEUTICS INC | -- | $191,494.32 | 1,842 | BYZR4X4 |
| 0.36% | NUVL | NUVALENT INC-A | -- | $186,100.85 | 2,483 | BMVBZD3 |
| 0.35% | CRSP | CRISPR THERAPEUTICS AG | -- | $179,029.71 | 3,231 | BDHF4K6 |
| 0.33% | MRUS | MERUS NV | -- | $167,314.00 | 2,590 | BZBY005 |
| 0.32% | ALKS | ALKERMES PLC | -- | $163,857.96 | 6,174 | B3P6D26 |
| 0.30% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $155,422.84 | 6,262 | 2713317 |
| 0.29% | KRYS | KRYSTAL BIOTECH INC | -- | $148,680.74 | 1,081 | BD6JX35 |
| 0.29% | CYTK | CYTOKINETICS INC | -- | $148,471.64 | 4,468 | BBBSBJ5 |
| 0.29% | ADMA | ADMA BIOLOGICS INC | -- | $146,306.16 | 8,932 | B9NSBM2 |
| 0.28% | AKRO | AKERO THERAPEUTICS INC | -- | $144,019.24 | 2,983 | BK7Y2V9 |
| 0.28% | PCVX | VAXCYTE INC | -- | $143,217.09 | 4,827 | BKPVGH6 |
| 0.28% | ACLX | ARCELLX INC | -- | $142,484.20 | 2,062 | BPCJ1Q2 |
| 0.25% | PTCT | PTC THERAPEUTICS INC | -- | $128,384.50 | 2,965 | B17VCN9 |
| 0.24% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $124,646.25 | 2,319 | BDCBCD8 |
| 0.24% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $122,057.11 | 1,853 | BJDX8Y8 |
| 0.22% | APLS | APELLIS PHARMACEUTICALS INC | -- | $112,142.70 | 4,702 | BYTQ6X1 |
| 0.22% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $111,745.92 | 3,552 | BFZQ0L8 |
| 0.22% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $110,749.44 | 3,056 | BMX9K07 |
| 0.21% | LGND | LIGAND PHARMACEUTICALS | -- | $106,141.22 | 722 | 2501578 |
| 0.20% | INDV | INDIVIOR PLC | -- | $104,049.72 | 4,668 | BP0BQQ5 |
| 0.20% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $103,657.84 | 11,726 | BFNF1D6 |
| 0.20% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $102,354.00 | 4,200 | BP8JSP4 |
| 0.19% | XENE | XENON PHARMACEUTICALS INC | -- | $97,929.81 | 2,871 | BRJ3GY4 |
| 0.19% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $96,878.43 | 3,537 | BJ62Z18 |
| 0.19% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $95,966.90 | 3,505 | BDD19F8 |
| 0.18% | IMVT | IMMUNOVANT INC | -- | $94,390.20 | 6,395 | BJRFSB7 |
| 0.18% | KYMR | KYMERA THERAPEUTICS INC | -- | $91,788.48 | 2,436 | BMPRZV5 |
| 0.17% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $88,924.07 | 5,167 | BYQBFJ8 |
| 0.17% | ALVO | ALVOTECH SA | -- | $85,055.16 | 9,983 | BPNTJ34 |
| 0.17% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $84,994.15 | 2,095 | B72ZBG4 |
| 0.16% | VCYT | VERACYTE INC | -- | $82,010.70 | 2,930 | BFTWZY0 |
| 0.16% | IBRX | IMMUNITYBIO INC | -- | $81,564.34 | 33,022 | BNSP0B8 |
| 0.15% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $79,101.37 | 14,953 | BM9FJ13 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $78,710.04 | 1,572 | BMH5RL1 |
| 0.15% | FOLD | AMICUS THERAPEUTICS INC | -- | $76,672.26 | 11,521 | B19FQ48 |
| 0.15% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $76,018.36 | 2,167 | BCBVTX1 |
| 0.15% | IRON | DISC MEDICINE INC | -- | $75,932.64 | 1,296 | BMGJZJ8 |
| 0.15% | DNLI | DENALI THERAPEUTICS INC | -- | $75,710.88 | 5,439 | BD2B4V0 |
| 0.15% | ZLAB | ZAI LAB LTD-ADR | -- | $75,073.56 | 2,166 | BD9GVY0 |
| 0.15% | OCUL | OCULAR THERAPEUTIX INC | -- | $74,857.60 | 5,960 | BNZB1X8 |
| 0.15% | IDYA | IDEAYA BIOSCIENCES INC | -- | $74,846.68 | 3,277 | BK0VHF6 |
| 0.15% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $74,750.40 | 2,148 | BKSGZN7 |
| 0.14% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $69,060.60 | 5,684 | BJ5FZ74 |
| 0.13% | ANIP | ANI PHARMACEUTICALS INC | -- | $68,752.80 | 810 | BCDWBX6 |
| 0.13% | CGON | CG ONCOLOGY INC | -- | $68,291.14 | 2,852 | BRBCSP4 |
| 0.13% | VCEL | VERICEL CORP | -- | $66,750.12 | 1,884 | BSBMN89 |
| 0.13% | SRPT | SAREPTA THERAPEUTICS INC | -- | $65,965.38 | 3,677 | B8DPDT7 |
| 0.13% | BEAM | BEAM THERAPEUTICS INC | -- | $64,609.06 | 3,764 | BK6L288 |
| 0.13% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $64,197.80 | 7,829 | 2100362 |
| 0.12% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $63,287.40 | 4,460 | BKX9VD3 |
| 0.12% | TWST | TWIST BIOSCIENCE CORP | -- | $61,946.46 | 2,242 | BGKG6G7 |
| 0.12% | SPRY | ARS PHARMACEUTICALS INC | -- | $60,196.50 | 3,675 | BMCR7V2 |
| 0.12% | APGE | APOGEE THERAPEUTICS INC | -- | $59,598.00 | 1,720 | BM9HHL5 |
| 0.12% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $59,347.53 | 3,573 | BLB0YQ9 |
| 0.11% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $57,778.65 | 5,055 | BFWLC09 |
| 0.11% | TVTX | TRAVERE THERAPEUTICS INC | -- | $57,421.44 | 3,323 | BLFGJD5 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $51,860.16 | 1,584 | BRXB0C0 |
| 0.10% | TXG | 10X GENOMICS INC-CLASS A | -- | $51,160.36 | 4,156 | BKS3RS7 |
| 0.10% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $51,102.66 | 3,934 | BKY5JZ8 |
| 0.10% | ABCL | ABCELLERA BIOLOGICS INC | -- | $50,251.50 | 11,167 | BL53SR3 |
| 0.10% | JANX | JANUX THERAPEUTICS INC | -- | $50,191.38 | 2,214 | BMFX8Y7 |
| 0.10% | NVAX | NOVAVAX INC | -- | $48,661.80 | 6,060 | BJDQXG4 |
| 0.09% | ARDX | ARDELYX INC | -- | $48,335.40 | 8,951 | BN89V40 |
| 0.09% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $48,263.04 | 1,764 | BNFWZS4 |
| 0.09% | VERA | VERA THERAPEUTICS INC | -- | $48,125.62 | 2,386 | BL55460 |
| 0.09% | ETNB | 89BIO INC | -- | $47,901.74 | 5,462 | BK1K484 |
| 0.09% | DYN | DYNE THERAPEUTICS INC | -- | $47,803.72 | 4,253 | BN15WD1 |
| 0.09% | GRFS | GRIFOLS SA-ADR | -- | $47,587.07 | 4,564 | B8K7T65 |
| 0.09% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $47,420.43 | 1,487 | BLCD809 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $47,064.18 | 4,493 | BRJZSK0 |
| 0.09% | WVE | WAVE LIFE SCIENCES LTD | -- | $46,741.54 | 5,767 | BYZG9R0 |
| 0.09% | COGT | COGENT BIOSCIENCES INC | -- | $46,561.80 | 4,260 | BLR6XK8 |
| 0.09% | HROW | HARROW INC | -- | $46,325.02 | 1,373 | BHNDW86 |
| 0.09% | AVDL | AVADEL PHARMACEUTICALS | -- | $46,287.01 | 3,619 | BDGMC59 |
| 0.09% | INVA | INNOVIVA INC | -- | $46,157.85 | 2,349 | BDDXF67 |
| 0.09% | CVAC | CUREVAC NV | -- | $45,742.32 | 8,424 | BN4RD42 |
| 0.09% | NVCR | NOVOCURE LTD | -- | $45,463.90 | 4,171 | BYSS4X4 |
| 0.09% | GRAL | GRAIL INC | -- | $44,000.74 | 1,346 | BSLSSX7 |
| 0.09% | PCRX | PACIRA BIOSCIENCES INC | -- | $43,629.08 | 1,732 | B3X26D8 |
| 0.09% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $43,476.42 | 1,203 | BX7RSN3 |
| 0.08% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $43,142.40 | 5,992 | BLR7H87 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $41,606.76 | 3,874 | BYZM6C2 |
| 0.08% | LENZ | LENZ THERAPEUTICS INC | -- | $40,824.81 | 1,053 | BQV0J03 |
| 0.08% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $40,269.69 | 3,219 | BN7Q7R7 |
| 0.08% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $39,029.79 | 2,229 | BQS9486 |
| 0.08% | MNKD | MANNKIND CORP | -- | $38,888.82 | 11,371 | BF081J4 |
| 0.07% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $36,251.90 | 3,194 | BYTYP72 |
| 0.07% | SYRE | SPYRE THERAPEUTICS INC | -- | $34,434.50 | 2,258 | BQBBDY8 |
| 0.07% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $34,251.90 | 762 | BQ721R4 |
| 0.07% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $33,259.14 | 1,836 | BMFD115 |
| 0.06% | GMAB | GENMAB A/S -SP ADR | -- | $33,074.52 | 1,569 | BBC9WC7 |
| 0.06% | ZYME | ZYMEWORKS INC | -- | $32,431.08 | 2,607 | BPCQZY9 |
| 0.06% | GERN | GERON CORP | -- | $32,408.80 | 23,830 | 2370381 |
| 0.06% | MLYS | MINERALYS THERAPEUTICS INC | -- | $32,157.22 | 2,438 | BP9N0G0 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $31,464.00 | 1,725 | BZ7PJQ1 |
| 0.06% | QURE | UNIQURE NV | -- | $28,917.76 | 2,048 | BJFSR88 |
| 0.06% | MNMD | MIND MEDICINE MINDMED INC | -- | $28,270.00 | 2,827 | BPQYY97 |
| 0.05% | TRVI | TREVI THERAPEUTICS INC | -- | $27,886.28 | 3,807 | BJH9ZN0 |
| 0.05% | NRIX | NURIX THERAPEUTICS INC | -- | $27,521.80 | 2,852 | BMVLGP2 |
| 0.05% | TSHA | TAYSHA GENE THERAPIES INC | -- | $26,956.92 | 9,767 | BNC1BX1 |
| 0.05% | STOK | STOKE THERAPEUTICS INC | -- | $26,885.88 | 2,043 | BJQ05Z6 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $26,851.36 | 2,612 | BJLKVS6 |
| 0.05% | EYPT | EYEPOINT PHARMACEUTICALS INC | -- | $26,458.13 | 2,575 | BMGS7L1 |
| 0.05% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $26,079.70 | 3,335 | BPCK358 |
| 0.05% | TNGX | TANGO THERAPEUTICS INC | -- | $25,992.55 | 4,055 | BP2P6L0 |
| 0.05% | CRMD | CORMEDIX INC | -- | $25,557.66 | 2,538 | BJ0LT31 |
| 0.05% | SIGA | SIGA TECHNOLOGIES INC | -- | $25,340.04 | 2,673 | 2107437 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $24,990.00 | 1,700 | BQS7491 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $24,641.88 | 8,439 | BMFJJ97 |
| 0.05% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $24,613.18 | 12,494 | BF0DMK7 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $24,472.00 | 2,660 | BKVDFF7 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $24,006.10 | 7,166 | BZ0QMB7 |
| 0.05% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,938.20 | 2,046 | BLFBZ32 |
| 0.05% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $23,574.88 | 3,007 | BFYQFJ2 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $23,268.60 | 1,860 | BD06CS0 |
| 0.04% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,384.74 | 669 | BQD3J33 |
| 0.04% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $22,372.80 | 3,792 | BLB0YH0 |
| 0.04% | AVBP | ARRIVENT BIOPHARMA INC | -- | $22,259.20 | 1,280 | BMGTLY5 |
| 0.04% | VIR | VIR BIOTECHNOLOGY INC | -- | $22,136.16 | 5,172 | BK4PZ38 |
| 0.04% | ANAB | ANAPTYSBIO INC | -- | $21,980.00 | 1,099 | BDRW1L7 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $21,755.10 | 762 | BL95N25 |
| 0.04% | FTRE | FORTREA HOLDINGS INC | -- | $21,636.54 | 3,386 | BRXYZ57 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $21,329.40 | 1,871 | BMNDK09 |
| 0.04% | RLAY | RELAY THERAPEUTICS INC | -- | $20,845.50 | 6,414 | BN2R582 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $20,692.80 | 1,080 | BKLCWZ3 |
| 0.04% | TERN | TERNS PHARMACEUTICALS INC | -- | $20,588.40 | 3,268 | BMDJ0C9 |
| 0.04% | KROS | KEROS THERAPEUTICS INC | -- | $20,292.00 | 1,520 | BM7V485 |
| 0.04% | TRML | TOURMALINE BIO INC | -- | $20,171.39 | 961 | BQ80NC6 |
| 0.04% | TYRA | TYRA BIOSCIENCES INC | -- | $20,099.00 | 1,990 | BMVNDH9 |
| 0.04% | RAPP | RAPPORT THERAPEUTICS INC | -- | $19,506.48 | 1,366 | BR3T9B6 |
| 0.04% | PGEN | PRECIGEN INC | -- | $19,216.56 | 11,044 | BKM5C84 |
| 0.04% | XNCR | XENCOR INC | -- | $18,641.00 | 2,663 | BGCYWN8 |
| 0.04% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $18,529.94 | 7,502 | BFMLGR4 |
| 0.04% | ORKA | ORUKA THERAPEUTICS INC | -- | $18,283.05 | 1,401 | BKVF0J2 |
| 0.04% | ARVN | ARVINAS INC | -- | $17,983.64 | 2,731 | BDZ30Q0 |
| 0.04% | HCM | HUTCHMED CHINA-ADR | -- | $17,956.80 | 1,160 | BYXV9H7 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $17,944.06 | 3,239 | BYZD465 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $17,632.00 | 2,900 | BQHN6C7 |
| 0.03% | SVRA | SAVARA INC | -- | $17,458.20 | 6,466 | BYXGN81 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,451.00 | 554 | B292NQ7 |
| 0.03% | PRME | PRIME MEDICINE INC | -- | $17,241.12 | 4,912 | BPBJFM7 |
| 0.03% | AURA | AURA BIOSCIENCES INC | -- | $15,868.80 | 2,320 | BP81R42 |
| 0.03% | ERAS | ERASCA INC | -- | $15,686.52 | 10,599 | BNLYBF3 |
| 0.03% | CGEM | CULLINAN THERAPEUTICS INC | -- | $15,675.99 | 2,211 | BM90J52 |
| 0.03% | ALMS | ALUMIS INC | -- | $15,519.84 | 3,576 | BPLQG36 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $15,454.89 | 699 | BPBPCG8 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $15,447.38 | 2,014 | B91XRN2 |
| 0.03% | PSNL | PERSONALIS INC | -- | $14,872.50 | 3,305 | BJQ0608 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $14,756.00 | 3,400 | BMC3HS7 |
| 0.03% | ITOS | ITEOS THERAPEUTICS INC | -- | $14,477.52 | 1,432 | BMWXFT4 |
| 0.03% | YMAB | Y-MABS THERAPEUTICS INC | -- | $14,441.40 | 1,695 | BG31GH0 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $14,391.16 | 2,884 | BDDVW37 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $14,343.76 | 3,716 | BYVQJ96 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $14,146.02 | 11,227 | B4N8MH9 |
| 0.03% | LXRX | LEXICON PHARMACEUTICALS INC | -- | $14,131.52 | 13,588 | BWFZX59 |
| 0.03% | ATXS | ASTRIA THERAPEUTICS INC | -- | $14,101.48 | 2,111 | BMYRFN8 |
| 0.03% | RGNX | REGENXBIO INC | -- | $14,002.42 | 1,877 | BZ0G875 |
| 0.03% | EOLS | EVOLUS INC | -- | $13,917.24 | 2,412 | BDRJH21 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $13,680.68 | 7,415 | BBNBTD2 |
| 0.03% | ABSI | ABSCI CORP | -- | $13,600.20 | 4,772 | BN94K69 |
| 0.02% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $12,607.45 | 2,885 | BYP80F1 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $12,316.46 | 1,651 | BKDQKM6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $11,770.52 | 4,031 | BDFKQ07 |
| 0.02% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $11,699.20 | 2,560 | BMZ4LN0 |
| 0.02% | INBX | INHIBRX BIOSCIENCES INC | -- | $11,598.80 | 542 | BNSP8K3 |
| 0.02% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $11,560.85 | 1,015 | BKC9SX3 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $11,239.02 | 3,202 | BLN9Z50 |
| 0.02% | AMRN | AMARIN CORP PLC -ADR | -- | $11,190.06 | 749 | BN72KB0 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $11,097.22 | 5,387 | BMCWKZ2 |
| 0.02% | NGNE | NEUROGENE INC | -- | $10,866.90 | 534 | BS2F741 |
| 0.02% | RNAC | CARTESIAN THERAPEUTICS INC | -- | $10,778.10 | 971 | BQB9HM8 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $10,258.30 | 3,035 | BFY7DC4 |
| 0.02% | DSGN | DESIGN THERAPEUTICS INC | -- | $10,237.68 | 2,124 | BMFK3H6 |
| 0.02% | HUMA | HUMACYTE INC | -- | $10,127.98 | 5,804 | BMYTJP4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $9,820.35 | 2,085 | BMF7DT9 |
| 0.02% | ANNX | ANNEXON INC | -- | $9,646.75 | 4,105 | BMVV9R5 |
| 0.02% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $9,641.19 | 2,301 | BP7KZP7 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $9,583.49 | 1,733 | BKLXFX5 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $9,238.95 | 2,205 | B12W3P6 |
| 0.02% | SCPH | SCPHARMACEUTICALS INC | -- | $9,203.50 | 1,975 | BYX2Z16 |
| 0.02% | OMER | OMEROS CORP | -- | $9,074.88 | 2,192 | B4NB858 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $9,056.88 | 2,396 | BMXNGZ6 |
| 0.02% | OABI | OMNIAB INC | -- | $8,970.92 | 4,577 | BN13S71 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $8,958.40 | 1,760 | BL5B6Z1 |
| 0.02% | THRD | THIRD HARMONIC BIO INC | -- | $8,941.56 | 1,662 | BNNPQY8 |
| 0.02% | TKNO | ALPHA TEKNOVA INC | -- | $8,815.59 | 1,999 | BP7L561 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $8,714.88 | 6,052 | BN4JN37 |
| 0.02% | CDXS | CODEXIS INC | -- | $8,680.00 | 3,100 | B5LL2C2 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $8,429.52 | 8,184 | BFZNYB7 |
| 0.02% | ALEC | ALECTOR INC | -- | $8,342.43 | 3,741 | BJ4LDC4 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $7,776.99 | 3,757 | BZC0D70 |
| 0.02% | CRGX | CARGO THERAPEUTICS INC | -- | $7,728.00 | 1,725 | BQHN2F2 |
| 0.01% | TRDA | ENTRADA THERAPEUTICS INC | -- | $7,118.36 | 1,418 | BP81RK8 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $6,890.40 | 3,132 | BZ8FPH3 |
| 0.01% | TVGN | TEVOGEN BIO HOLDINGS INC | -- | $6,742.40 | 6,880 | BPG5P75 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $6,429.94 | 2,657 | BKX9NQ0 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $6,375.60 | 2,070 | BY7RB53 |
| 0.01% | LYEL | LYELL IMMUNOPHARMA INC | -- | $5,840.16 | 552 | BTNMG41 |
| 0.01% | LXEO | LEXEO THERAPEUTICS INC | -- | $5,514.48 | 1,242 | BQ6C357 |
| 0.01% | NKTX | NKARTA INC | -- | $5,336.55 | 2,655 | BK80YJ8 |
| 0.01% | MXCT | MAXCYTE INC | -- | $5,250.96 | 3,978 | BKMQF66 |
| 0.01% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $5,192.00 | 800 | B9L5200 |
| 0.01% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $5,062.96 | 6,054 | B3MZ6K5 |
| 0.01% | KYTX | KYVERNA THERAPEUTICS INC | -- | $5,012.70 | 1,617 | BSMLR16 |
| 0.01% | CLYM | CLIMB BIO INC | -- | $4,171.20 | 2,528 | BMW5LX6 |
| 0.01% | FATE | FATE THERAPEUTICS INC | -- | $4,013.22 | 4,289 | BCZS820 |
| 0.01% | PLRX | PLIANT THERAPEUTICS INC | -- | $3,904.90 | 2,297 | BMDWW66 |
| 0.01% | MGNX | MACROGENICS INC | -- | $3,469.20 | 2,360 | BFDV8K0 |
| 0.01% | TCRX | TSCAN THERAPEUTICS INC | -- | $3,150.77 | 1,957 | BNLYBJ7 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $2,441.42 | 3,160 | BF12XC2 |
| -- | PYXS | PYXIS ONCOLOGY INC | -- | $2,410.72 | 2,318 | BLBR8D5 |
| -- | APLT | APPLIED THERAPEUTICS INC | -- | $2,378.88 | 5,297 | BJL38Z1 |
| -- | ARTV | ARTIVA BIOTHERAPEUTICS INC | -- | $2,334.72 | 912 | BMF1LJ7 |
| -- | BMEA | BIOMEA FUSION INC | -- | $2,151.18 | 1,406 | BNKF6N0 |
| -- | ACRV | ACRIVON THERAPEUTICS INC | -- | $1,442.79 | 1,173 | BP2TPK4 |
| -- | PEPG | PEPGEN INC | -- | $1,236.24 | 1,224 | BMTX3D7 |
| -- | MRSN | MERSANA THERAPEUTICS INC | -- | $1,116.39 | 187 | BVPKH99 |
| -- | OKUR | ONKURE THERAPEUTICS INC-A | -- | $974.40 | 480 | BT7KGT6 |
| -- | QTTB | Q32 BIO INC | -- | $816.24 | 456 | BS2FKQ4 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 32.13% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 16,426,442 | -- | 3,675 | -- |
| 27.34% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 13,977,002 | -- | 3,127 | -- |
| 20.74% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 10,602,318 | -- | 2,372 | -- |
| 17.48% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 8,935,090 | -- | 1,999 | -- |
| 16.82% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 8,599,857 | -- | 1,924 | -- |
| 16.78% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 8,577,508 | -- | 1,919 | -- |
| -- | -- | TREASURY BILL | -- | $4,966,287.50 | 5,000,000 | BRF3QJ3 |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $11,050,435.07 | 11,050,435 | -- |
Index
as of 6/30/2025
- Total Number of Companies260
- Price/Earnings Ratio--
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$5.68 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2025
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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