BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
View fund details
Documents & Downloads
ETF & Index
Prospectus & Regulatory
You may order paper copies by contacting ProShares Client Services at 866-PRO-5125 (866-776-5125)
Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 12/31/2025
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/27/2026- NAV $87.37
- NAV Change $+0.99
- Market Price $87.36
- Market Price Change $+0.99
- Trading Volume (M) 15,012
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 1/27/2026- NAV $87.37
- NAV Change $+0.99
- Market Price $87.36
- Market Price Change $+0.99
- Trading Volume (M) 15,012
- 30-Day Median Bid Ask Spread 0.27%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 1/27/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.22% | GILD | GILEAD SCIENCES INC | -- | $5,704,069.11 | 40,463 | 2369174 |
| 6.07% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,568,178.31 | 11,743 | 2931034 |
| 5.64% | AMGN | AMGEN INC | -- | $5,178,105.48 | 14,739 | 2023607 |
| 4.07% | REGN | REGENERON PHARMACEUTICALS | -- | $3,729,765.00 | 4,836 | 2730190 |
| 2.39% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $2,194,483.50 | 6,186 | B00FWN1 |
| 1.77% | INSM | INSMED INC | -- | $1,624,123.04 | 9,986 | 2614487 |
| 1.30% | BIIB | BIOGEN INC | -- | $1,196,030.28 | 6,869 | 2455965 |
| 1.28% | ARGX | ARGENX SE - ADR | -- | $1,178,204.46 | 1,363 | BDVLM39 |
| 1.19% | ILMN | ILLUMINA INC | -- | $1,088,051.86 | 7,154 | 2613990 |
| 1.05% | UTHR | UNITED THERAPEUTICS CORP | -- | $961,188.48 | 2,016 | 2430412 |
| 1.04% | INCY | INCYTE CORP | -- | $951,096.24 | 9,192 | 2471950 |
| 0.99% | RVMD | REVOLUTION MEDICINES INC | -- | $903,570.64 | 9,052 | BL71K91 |
| 0.91% | MRNA | MODERNA INC | -- | $831,371.40 | 18,292 | BGSXTS3 |
| 0.89% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $815,003.70 | 20,005 | BMVP7Y0 |
| 0.87% | MEDP | MEDPACE HOLDINGS INC | -- | $794,367.75 | 1,319 | BDCBC61 |
| 0.80% | ROIV | ROIVANT SCIENCES LTD | -- | $733,666.92 | 32,564 | BMW4NZ9 |
| 0.77% | VTRS | VIATRIS INC | -- | $707,535.36 | 53,928 | BMWS3X9 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $702,543.14 | 9,022 | BK1KWG8 |
| 0.76% | GH | GUARDANT HEALTH INC | -- | $694,186.22 | 6,058 | BFXC911 |
| 0.75% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $686,550.00 | 2,875 | BV9G6B8 |
| 0.68% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $624,998.52 | 4,668 | 2623911 |
| 0.68% | IONS | IONIS PHARMACEUTICALS INC | -- | $622,949.76 | 7,584 | BDJ0LS6 |
| 0.64% | SNY | SANOFI-ADR | -- | $588,401.10 | 12,390 | 2964557 |
| 0.62% | BNTX | BIONTECH SE-ADR | -- | $564,955.56 | 4,734 | BK6H543 |
| 0.60% | SMMT | SUMMIT THERAPEUTICS INC | -- | $554,210.40 | 34,856 | BMTVQS7 |
| 0.60% | EXEL | EXELIXIS INC | -- | $549,111.96 | 12,554 | 2576941 |
| 0.59% | TEM | TEMPUS AI INC | -- | $540,760.14 | 8,094 | BSLSJJ0 |
| 0.58% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $531,914.57 | 1,063 | BD59BS7 |
| 0.56% | RNA | AVIDITY BIOSCIENCES INC | -- | $512,475.20 | 7,055 | BMWHPY1 |
| 0.56% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $511,365.75 | 8,995 | 2437071 |
| 0.54% | ONC | BEONE MEDICINES LTD-ADR | -- | $495,499.84 | 1,474 | BYYWPW6 |
| 0.52% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $477,533.25 | 2,845 | B4Q5ZN4 |
| 0.48% | AXSM | AXSOME THERAPEUTICS INC | -- | $443,727.20 | 2,360 | BYZR4X4 |
| 0.46% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $425,480.69 | 6,359 | BYQBFJ8 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $386,631.32 | 5,506 | 2975098 |
| 0.41% | KRYS | KRYSTAL BIOTECH INC | -- | $376,654.88 | 1,358 | BD6JX35 |
| 0.40% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $368,572.25 | 1,171 | BQ721R4 |
| 0.40% | CYTK | CYTOKINETICS INC | -- | $366,457.25 | 5,725 | BBBSBJ5 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $360,013.90 | 3,382 | BMVBZD3 |
| 0.37% | CAI | CARIS LIFE SCIENCES INC | -- | $343,618.11 | 13,211 | BT18HP9 |
| 0.36% | PCVX | VAXCYTE INC | -- | $333,111.15 | 6,129 | BKPVGH6 |
| 0.36% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $329,781.25 | 3,125 | BF2YWG4 |
| 0.36% | ABVX | ABIVAX SA-ADR | -- | $328,611.96 | 2,764 | BLC89B2 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $283,766.91 | 3,759 | B17VCN9 |
| 0.31% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $280,076.79 | 3,129 | BQS9486 |
| 0.30% | COGT | COGENT BIOSCIENCES INC | -- | $276,771.37 | 7,187 | BLR6XK8 |
| 0.30% | IBRX | IMMUNITYBIO INC | -- | $274,402.10 | 46,118 | BNSP0B8 |
| 0.28% | ALKS | ALKERMES PLC | -- | $259,143.12 | 7,731 | B3P6D26 |
| 0.27% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $243,175.16 | 2,927 | BDCBCD8 |
| 0.26% | KYMR | KYMERA THERAPEUTICS INC | -- | $243,073.35 | 3,369 | BMPRZV5 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $242,108.12 | 4,462 | BDHF4K6 |
| 0.26% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $238,843.62 | 2,406 | BJDX8Y8 |
| 0.26% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $235,323.50 | 4,443 | BDD19F8 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $220,193.81 | 8,207 | BJRFSB7 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $210,096.24 | 4,776 | BFZQ0L8 |
| 0.23% | CGON | CG ONCOLOGY INC | -- | $208,112.70 | 3,777 | BRBCSP4 |
| 0.23% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $207,530.20 | 7,921 | 2713317 |
| 0.23% | FOLD | AMICUS THERAPEUTICS INC | -- | $206,433.34 | 14,446 | B19FQ48 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $203,563.77 | 14,719 | BFNF1D6 |
| 0.22% | -- | INDIVIOR PHARMACEUTICALS INC COMMON STOCK USD 0.001 | -- | $203,020.56 | 5,844 | -- |
| 0.22% | GRAL | GRAIL INC | -- | $198,888.50 | 1,825 | BSLSSX7 |
| 0.20% | APGE | APOGEE THERAPEUTICS INC | -- | $185,799.46 | 2,567 | BM9HHL5 |
| 0.20% | ACLX | ARCELLX INC | -- | $185,456.57 | 2,707 | BPCJ1Q2 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $184,767.52 | 11,144 | B9NSBM2 |
| 0.20% | LGND | LIGAND PHARMACEUTICALS | -- | $180,241.78 | 922 | 2501578 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $173,232.67 | 5,309 | BP8JSP4 |
| 0.17% | XENE | XENON PHARMACEUTICALS INC | -- | $153,367.02 | 3,618 | BRJ3GY4 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $151,002.55 | 5,735 | BKX9VD3 |
| 0.16% | TERN | TERNS PHARMACEUTICALS INC | -- | $148,009.62 | 4,218 | BMDJ0C9 |
| 0.16% | VCYT | VERACYTE INC | -- | $147,299.80 | 3,701 | BFTWZY0 |
| 0.16% | DNLI | DENALI THERAPEUTICS INC | -- | $145,923.75 | 6,867 | BD2B4V0 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $145,855.70 | 4,751 | BK6L288 |
| 0.16% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $145,537.52 | 4,957 | BKY5JZ8 |
| 0.16% | IRON | DISC MEDICINE INC | -- | $145,223.52 | 1,768 | BMGJZJ8 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $142,607.70 | 4,105 | BK0VHF6 |
| 0.15% | VERA | VERA THERAPEUTICS INC | -- | $139,829.25 | 2,991 | BL55460 |
| 0.15% | ERAS | ERASCA INC | -- | $139,482.00 | 13,284 | BNLYBF3 |
| 0.15% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $137,456.04 | 7,148 | BJ5FZ74 |
| 0.15% | TARS | TARSUS PHARMACEUTICALS INC | -- | $135,482.20 | 1,988 | BMH5RL1 |
| 0.14% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $132,746.40 | 2,685 | B72ZBG4 |
| 0.14% | APLS | APELLIS PHARMACEUTICALS INC | -- | $129,137.01 | 5,921 | BYTQ6X1 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $125,795.67 | 4,189 | BLFGJD5 |
| 0.13% | TWST | TWIST BIOSCIENCE CORP | -- | $121,963.80 | 2,863 | BGKG6G7 |
| 0.13% | MLYS | MINERALYS THERAPEUTICS INC | -- | $121,672.20 | 3,705 | BP9N0G0 |
| 0.13% | SYRE | SPYRE THERAPEUTICS INC | -- | $121,196.88 | 3,633 | BQBBDY8 |
| 0.13% | DYN | DYNE THERAPEUTICS INC | -- | $120,633.48 | 6,687 | BN15WD1 |
| 0.13% | ALMS | ALUMIS INC | -- | $118,352.00 | 4,552 | BPLQG36 |
| 0.13% | TXG | 10X GENOMICS INC-CLASS A | -- | $117,915.48 | 5,454 | BKS3RS7 |
| 0.13% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $117,396.83 | 4,517 | BLB0YQ9 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $111,208.54 | 4,517 | BJ62Z18 |
| 0.12% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $110,745.00 | 24,075 | BM9FJ13 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $108,766.02 | 4,906 | B8DPDT7 |
| 0.12% | OCUL | OCULAR THERAPEUTIX INC | -- | $108,228.75 | 9,975 | BNZB1X8 |
| 0.11% | WVE | WAVE LIFE SCIENCES LTD | -- | $104,622.16 | 7,831 | BYZG9R0 |
| 0.11% | MAZE | MAZE THERAPEUTICS INC | -- | $102,151.02 | 2,253 | BSRK699 |
| 0.11% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $101,622.96 | 2,697 | BKSGZN7 |
| 0.10% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $96,126.30 | 3,683 | BMZ4LN0 |
| 0.10% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $94,413.60 | 2,115 | BRXB0C0 |
| 0.10% | GMAB | GENMAB A/S -SP ADR | -- | $94,152.80 | 2,737 | BBC9WC7 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $92,119.86 | 4,746 | BMVLGP2 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $90,706.00 | 2,090 | BQKXDX4 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $89,940.61 | 6,173 | BFWLC09 |
| 0.10% | ARDX | ARDELYX INC | -- | $89,764.53 | 11,377 | BN89V40 |
| 0.09% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $86,731.70 | 4,070 | BN7Q7R7 |
| 0.09% | VCEL | VERICEL CORP | -- | $86,621.44 | 2,368 | BSBMN89 |
| 0.09% | DVAX | DYNAVAX TECHNOLOGIES CORP | -- | $85,109.04 | 5,498 | BRJZSK0 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $84,633.40 | 1,052 | BCDWBX6 |
| 0.09% | UPB | UPSTREAM BIO INC | -- | $82,225.00 | 2,530 | BRCFFK6 |
| 0.09% | PHVS | PHARVARIS NV | -- | $81,542.81 | 2,999 | BMZ2X38 |
| 0.09% | ZYME | ZYMEWORKS INC | -- | $81,468.00 | 3,504 | BPCQZY9 |
| 0.09% | -- | DEFINIUM THERAPEUTICS INC COMMON STOCK USD 0 | -- | $80,617.76 | 4,612 | -- |
| 0.09% | NTLA | INTELLIA THERAPEUTICS INC | -- | $80,423.09 | 5,423 | BYZM6C2 |
| 0.09% | MNKD | MANNKIND CORP | -- | $80,373.02 | 14,378 | BF081J4 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $79,546.74 | 5,142 | BPCK358 |
| 0.09% | ORKA | ORUKA THERAPEUTICS INC | -- | $79,118.30 | 2,267 | BKVF0J2 |
| 0.09% | STOK | STOKE THERAPEUTICS INC | -- | $78,939.25 | 2,675 | BJQ05Z6 |
| 0.09% | TYRA | TYRA BIOSCIENCES INC | -- | $78,468.60 | 2,499 | BMVNDH9 |
| 0.09% | PGEN | PRECIGEN INC | -- | $78,361.91 | 16,567 | BKM5C84 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $78,269.10 | 2,730 | BCBVTX1 |
| 0.08% | ALVO | ALVOTECH SA | -- | $77,823.36 | 14,656 | BPNTJ34 |
| 0.08% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $77,213.76 | 3,497 | BYP80F1 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $75,819.14 | 2,102 | BQXJKH2 |
| 0.08% | TNGX | TANGO THERAPEUTICS INC | -- | $74,726.10 | 6,306 | BP2P6L0 |
| 0.08% | NVAX | NOVAVAX INC | -- | $74,720.38 | 7,609 | BJDQXG4 |
| 0.08% | RAPT | RAPT THERAPEUTICS INC | -- | $74,720.17 | 1,297 | BTJZB49 |
| 0.08% | HROW | HARROW INC | -- | $74,527.32 | 1,734 | BHNDW86 |
| 0.08% | FTRE | FORTREA HOLDINGS INC | -- | $74,061.12 | 4,326 | BRXYZ57 |
| 0.08% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $72,698.64 | 2,779 | BMFD115 |
| 0.08% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $72,020.34 | 3,942 | BMX9K07 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $71,607.15 | 2,043 | BLCD809 |
| 0.08% | QURE | UNIQURE NV | -- | $71,087.29 | 2,917 | BJFSR88 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $70,431.90 | 3,049 | BP7KZP7 |
| 0.08% | INVA | INNOVIVA INC | -- | $69,039.72 | 3,501 | BDDXF67 |
| 0.08% | RLAY | RELAY THERAPEUTICS INC | -- | $68,977.50 | 8,115 | BN2R582 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $68,421.15 | 5,243 | BYSS4X4 |
| 0.07% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $67,073.60 | 1,480 | BX7RSN3 |
| 0.07% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $66,640.08 | 9,858 | 2100362 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $66,319.50 | 17,005 | BWJDYK1 |
| 0.07% | TRVI | TREVI THERAPEUTICS INC | -- | $65,803.84 | 6,004 | BJH9ZN0 |
| 0.07% | ANAB | ANAPTYSBIO INC | -- | $64,450.08 | 1,296 | BDRW1L7 |
| 0.07% | SANA | SANA BIOTECHNOLOGY INC | -- | $61,985.84 | 12,472 | BMFJJ97 |
| 0.07% | EYPT | EYEPOINT INC | -- | $61,279.56 | 3,876 | BMGS7L1 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $61,112.16 | 2,232 | BR3T9B6 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $61,047.00 | 12,825 | BNC1BX1 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $60,932.52 | 2,484 | BFXC933 |
| 0.06% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $59,270.31 | 4,807 | BLB0YH0 |
| 0.06% | CSTL | CASTLE BIOSCIENCES INC | -- | $58,562.28 | 1,367 | BKLCWZ3 |
| 0.06% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $58,345.19 | 7,769 | BLR7H87 |
| 0.06% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $56,490.00 | 2,152 | BNFWZS4 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $55,919.85 | 14,015 | BL53SR3 |
| 0.06% | SVRA | SAVARA INC | -- | $55,732.95 | 9,527 | BYXGN81 |
| 0.06% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $55,389.26 | 18,587 | BF0DMK7 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $55,221.60 | 4,560 | BKVDFF7 |
| 0.06% | SEPN | SEPTERNA INC | -- | $53,343.20 | 2,096 | BQNKXX2 |
| 0.06% | GRFS | GRIFOLS SA-ADR | -- | $53,064.48 | 5,712 | B8K7T65 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $50,435.91 | 2,513 | BQB42H3 |
| 0.05% | VIR | VIR BIOTECHNOLOGY INC | -- | $50,092.66 | 6,514 | BK4PZ38 |
| 0.05% | INBX | INHIBRX BIOSCIENCES INC | -- | $50,046.69 | 681 | BNSP8K3 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $48,779.12 | 4,628 | BMCR7V2 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $47,895.20 | 2,192 | BZ7PJQ1 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $47,400.13 | 3,331 | BJLKVS6 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $47,073.84 | 2,904 | BP6C0S2 |
| 0.05% | CTMX | CYTOMX THERAPEUTICS INC | -- | $47,042.69 | 7,933 | BYWVTY5 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $47,032.86 | 2,373 | BMNDK09 |
| 0.05% | VTYX | VENTYX BIOSCIENCES INC | -- | $46,740.59 | 3,341 | BMG99Y1 |
| 0.05% | AVBP | ARRIVENT BIOPHARMA INC | -- | $44,671.63 | 1,933 | BMGTLY5 |
| 0.05% | ANNX | ANNEXON INC | -- | $44,524.89 | 6,777 | BMVV9R5 |
| 0.05% | XNCR | XENCOR INC | -- | $44,040.48 | 3,344 | BGCYWN8 |
| 0.05% | MESO | MESOBLAST LTD- SPON ADR | -- | $44,014.32 | 2,296 | BQS7491 |
| 0.05% | BCAX | BICARA THERAPEUTICS INC | -- | $43,015.05 | 2,565 | BQB42F1 |
| 0.05% | PSNL | PERSONALIS INC | -- | $42,910.56 | 4,158 | BJQ0608 |
| 0.05% | OMER | OMEROS CORP | -- | $42,064.40 | 3,320 | B4NB858 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $41,479.68 | 2,816 | BMFX8Y7 |
| 0.04% | GERN | GERON CORP | -- | $41,246.82 | 29,889 | 2370381 |
| 0.04% | ARVN | ARVINAS INC | -- | $40,955.34 | 3,007 | BDZ30Q0 |
| 0.04% | PCRX | PACIRA BIOSCIENCES INC | -- | $39,977.90 | 2,014 | B3X26D8 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $39,151.38 | 7,617 | B3MZ6K5 |
| 0.04% | ESPR | ESPERION THERAPEUTICS INC | -- | $38,280.06 | 11,193 | BBNBTD2 |
| 0.04% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $37,899.68 | 959 | BL95N25 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $37,460.80 | 9,005 | BZ0QMB7 |
| 0.04% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $36,329.52 | 14,136 | B4N8MH9 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $36,174.56 | 8,452 | BPBJFM7 |
| 0.04% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $35,362.98 | 2,367 | BD06CS0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $34,506.78 | 4,074 | BYZD465 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $34,132.44 | 2,766 | BM90J52 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $32,908.40 | 1,679 | BT9K6D8 |
| 0.03% | RGNX | REGENXBIO INC | -- | $31,781.70 | 2,370 | BZ0G875 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $31,662.50 | 850 | BQD3J33 |
| 0.03% | ZLAB | ZAI LAB LTD-ADR | -- | $31,252.65 | 1,833 | BD9GVY0 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $30,839.88 | 4,412 | BMC3HS7 |
| 0.03% | ALT | ALTIMMUNE INC | -- | $30,195.48 | 4,886 | BFY7DC4 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $30,189.69 | 3,769 | BFYQFJ2 |
| 0.03% | GOSS | GOSSAMER BIO INC | -- | $28,609.68 | 10,837 | BJ0CK86 |
| 0.03% | CRMD | CORMEDIX INC | -- | $28,589.75 | 3,689 | BJ0LT31 |
| 0.03% | LENZ | LENZ THERAPEUTICS INC | -- | $28,406.35 | 1,465 | BQV0J03 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $28,243.53 | 2,667 | BMFK3H6 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $27,721.96 | 2,534 | BJDX8Z9 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $27,657.69 | 3,673 | BDDVW37 |
| 0.03% | IVVD | INVIVYD INC | -- | $26,339.25 | 12,975 | BM8NHS1 |
| 0.03% | KROS | KEROS THERAPEUTICS INC | -- | $26,095.80 | 1,426 | BM7V485 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $25,802.00 | 6,790 | BMCWKZ2 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $25,764.18 | 3,417 | BQ6C357 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $25,103.04 | 993 | BTNMG41 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $24,519.60 | 2,520 | B91XRN2 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,967.36 | 3,648 | BQHN6C7 |
| 0.03% | KMDA | KAMADA LTD | -- | $23,957.87 | 2,701 | B2Q9833 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $23,539.48 | 2,636 | BLFBZ32 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $23,451.28 | 677 | B292NQ7 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $22,867.46 | 3,353 | 2107437 |
| 0.02% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $22,710.75 | 2,675 | BKLXFX5 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $22,191.34 | 2,767 | B12W3P6 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $21,124.15 | 4,183 | BYTYP72 |
| 0.02% | ABSI | ABSCI CORP | -- | $20,982.18 | 7,041 | BN94K69 |
| 0.02% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $19,820.64 | 5,712 | BYVQJ96 |
| 0.02% | TRDA | ENTRADA THERAPEUTICS INC | -- | $19,690.00 | 1,790 | BP81RK8 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $19,632.51 | 5,073 | BYV2W40 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $19,374.64 | 4,868 | BKRRKY7 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $19,033.28 | 2,051 | BSMLR16 |
| 0.02% | ETON | ETON PHARMACEUTICALS INC | -- | $18,890.24 | 1,256 | BGL0JK3 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $18,469.00 | 5,060 | BDFKQ07 |
| 0.02% | PEPG | PEPGEN INC | -- | $18,026.40 | 3,219 | BMTX3D7 |
| 0.02% | TECX | TECTONIC THERAPEUTIC INC | -- | $17,844.12 | 876 | BPBPCG8 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $17,535.98 | 1,351 | B9L5200 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,827.18 | 2,973 | BP81R42 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $16,662.99 | 7,823 | BN4JN37 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $16,641.54 | 4,701 | BZC0D70 |
| 0.02% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $16,098.66 | 10,522 | BFZNYB7 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,810.29 | 3,023 | BMVBZF5 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $15,677.00 | 2,570 | BP0TQC5 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $15,623.20 | 2,648 | BMF7DT9 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,498.63 | 2,359 | B7F2TY6 |
| 0.02% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $15,313.62 | 2,166 | BKDQKM6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,245.38 | 1,082 | BPRBTY7 |
| 0.02% | LFCR | LIFECORE BIOMEDICAL INC | -- | $15,207.18 | 1,754 | 2517058 |
| 0.02% | EOLS | EVOLUS INC | -- | $15,023.25 | 3,035 | BDRJH21 |
| 0.02% | AARD | AARDVARK THERAPEUTICS INC | -- | $14,979.30 | 1,019 | BTXQTX3 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $14,888.06 | 3,658 | BLN9Z50 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $14,709.36 | 4,008 | BMXNGZ6 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,405.75 | 725 | BS2F741 |
| 0.02% | CHRS | COHERUS ONCOLOGY INC | -- | $14,204.09 | 5,659 | BRK0149 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $13,611.14 | 4,507 | BK5MWR1 |
| 0.01% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $13,336.64 | 9,392 | BFMLGR4 |
| 0.01% | OABI | OMNIAB INC | -- | $13,210.40 | 6,740 | BN13S71 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $11,645.64 | 789 | BRJJYT3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $11,261.88 | 9,156 | BNR5QT9 |
| 0.01% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $11,236.89 | 2,199 | BL5B6Z1 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,999.04 | 2,644 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $10,870.46 | 2,759 | BY7RB53 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $10,715.60 | 3,560 | BPTK6Z2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,921.80 | 1,330 | BKC9SX3 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $9,711.32 | 4,538 | BKX9NQ0 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $9,644.81 | 4,571 | BZ8FPH3 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,031.04 | 8,768 | BMYTJP4 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $8,842.68 | 1,452 | BP2NYN2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,918.96 | 2,506 | BP7L561 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,910.12 | 2,668 | BKTV702 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $6,782.80 | 4,376 | BNYJR68 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $6,302.46 | 4,567 | BNNXX18 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,047.47 | 4,229 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $5,440.05 | 7,796 | BNNXX52 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,780.60 | 2,915 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $16.62 | 01 | BTFHQP5 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| 41.12% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 37,723,434 | -- | 6,292 | -- |
| 28.86% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 26,469,956 | -- | 4,415 | -- |
| 23.38% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,445,760 | -- | 3,577 | -- |
| 17.25% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,822,019 | -- | 2,639 | -- |
| 16.24% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,892,723 | -- | 2,484 | -- |
| 4.14% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,795,126 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $28,865,037.62 | 28,865,038 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
Read More