BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 2/28/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | 6.03% | 5.70% | 60.37% | 10.56% | 62.26% | 19.25% | -0.31% | 8.72% | 16.98% | 04/07/2010 |
| BIB Market Price | 6.05% | 5.51% | 60.28% | 10.49% | 62.05% | 19.26% | -0.28% | 8.72% | 16.98% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -4.51% | 34.14% | 74.98% | 59.23% | 59.23% | 12.41% | -1.02% | 1.38% | 16.43% | 04/07/2010 |
| BIB NAV | -4.39% | 34.17% | 75.09% | 59.34% | 59.34% | 12.29% | -1.01% | 1.39% | 16.43% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/13/2026- NAV $78.64
- NAV Change $-0.80
- Market Price $78.64
- Market Price Change $-0.78
- Trading Volume (M) 10,316
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time 4:00 p.m. ET
- Distributions Quarterly
- Options Available Yes
Price
as of 3/13/2026- NAV $78.64
- NAV Change $-0.80
- Market Price $78.64
- Market Price Change $-0.78
- Trading Volume (M) 10,316
- 30-Day Median Bid Ask Spread 0.25%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 12/31/2025
Holdings
as of 3/13/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 6.98% | GILD | GILEAD SCIENCES INC | -- | $5,545,142.55 | 38,245 | 2369174 |
| 6.56% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $5,208,735.32 | 11,098 | 2931034 |
| 6.42% | AMGN | AMGEN INC | -- | $5,102,403.93 | 13,933 | 2023607 |
| 4.29% | REGN | REGENERON PHARMACEUTICALS | -- | $3,408,914.67 | 4,571 | 2730190 |
| 2.31% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,832,194.86 | 5,846 | B00FWN1 |
| 1.66% | INSM | INSMED INC | -- | $1,316,461.50 | 9,437 | 2614487 |
| 1.48% | BIIB | BIOGEN INC | -- | $1,178,622.60 | 6,492 | 2455965 |
| 1.29% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,020,772.48 | 1,904 | 2430412 |
| 1.14% | MRNA | MODERNA INC | -- | $908,709.84 | 17,289 | BGSXTS3 |
| 1.14% | ARGX | ARGENX SE - ADR | -- | $901,479.15 | 1,287 | BDVLM39 |
| 1.09% | ROIV | ROIVANT SCIENCES LTD | -- | $863,658.74 | 30,779 | BMW4NZ9 |
| 1.09% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $863,241.50 | 18,910 | BMVP7Y0 |
| 1.02% | RVMD | REVOLUTION MEDICINES INC | -- | $811,527.30 | 8,555 | BL71K91 |
| 1.01% | ILMN | ILLUMINA INC | -- | $804,153.34 | 6,761 | 2613990 |
| 1.01% | INCY | INCYTE CORP | -- | $803,894.98 | 8,687 | 2471950 |
| 0.87% | VTRS | VIATRIS INC | -- | $688,631.72 | 50,972 | BMWS3X9 |
| 0.77% | ASND | ASCENDIS PHARMA A/S - ADR | -- | $614,213.64 | 2,718 | BV9G6B8 |
| 0.75% | BBIO | BRIDGEBIO PHARMA INC | -- | $591,928.48 | 8,528 | BK1KWG8 |
| 0.72% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $572,589.36 | 4,412 | 2623911 |
| 0.71% | MEDP | MEDPACE HOLDINGS INC | -- | $561,661.27 | 1,247 | BDCBC61 |
| 0.67% | SMMT | SUMMIT THERAPEUTICS INC | -- | $531,105.64 | 32,947 | BMTVQS7 |
| 0.64% | SNY | SANOFI-ADR | -- | $510,643.20 | 11,712 | 2964557 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $510,218.73 | 7,167 | BDJ0LS6 |
| 0.63% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $497,452.02 | 8,502 | 2437071 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $489,430.25 | 5,725 | BFXC911 |
| 0.62% | EXEL | EXELIXIS INC | -- | $489,312.60 | 11,865 | 2576941 |
| 0.60% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $480,120.95 | 2,689 | B4Q5ZN4 |
| 0.56% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $446,164.49 | 1,003 | BD59BS7 |
| 0.51% | BNTX | BIONTECH SE-ADR | -- | $407,984.06 | 4,474 | BK6H543 |
| 0.50% | ONC | BEONE MEDICINES LTD-ADR | -- | $395,965.70 | 1,394 | BYYWPW6 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $382,297.02 | 7,649 | BSLSJJ0 |
| 0.46% | IBRX | IMMUNITYBIO INC | -- | $365,728.49 | 43,591 | BNSP0B8 |
| 0.44% | AXSM | AXSOME THERAPEUTICS INC | -- | $348,214.48 | 2,231 | BYZR4X4 |
| 0.42% | HALO | HALOZYME THERAPEUTICS INC | -- | $331,350.30 | 5,205 | 2975098 |
| 0.42% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $330,850.50 | 6,010 | BYQBFJ8 |
| 0.41% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $325,402.65 | 1,107 | BQ721R4 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $325,044.72 | 5,412 | BBBSBJ5 |
| 0.40% | KRYS | KRYSTAL BIOTECH INC | -- | $316,987.32 | 1,282 | BD6JX35 |
| 0.40% | PCVX | VAXCYTE INC | -- | $316,127.36 | 5,792 | BKPVGH6 |
| 0.39% | NUVL | NUVALENT INC-A | -- | $313,082.21 | 3,197 | BMVBZD3 |
| 0.38% | ABVX | ABIVAX SA-ADR | -- | $301,686.00 | 2,612 | BLC89B2 |
| 0.37% | ACLX | ARCELLX INC | -- | $292,724.01 | 2,559 | BPCJ1Q2 |
| 0.32% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $258,033.14 | 2,953 | BF2YWG4 |
| 0.32% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $255,560.12 | 2,767 | BDCBCD8 |
| 0.32% | KYMR | KYMERA THERAPEUTICS INC | -- | $251,631.52 | 3,184 | BMPRZV5 |
| 0.29% | COGT | COGENT BIOSCIENCES INC | -- | $230,996.00 | 6,794 | BLR6XK8 |
| 0.29% | CGON | CG ONCOLOGY INC | -- | $229,451.01 | 3,569 | BRBCSP4 |
| 0.29% | PTCT | PTC THERAPEUTICS INC | -- | $229,197.46 | 3,554 | B17VCN9 |
| 0.29% | CAI | CARIS LIFE SCIENCES INC | -- | $226,620.90 | 12,486 | BT18HP9 |
| 0.26% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $206,160.84 | 2,274 | BJDX8Y8 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $205,578.75 | 4,217 | BDHF4K6 |
| 0.26% | ALKS | ALKERMES PLC | -- | $202,814.56 | 7,306 | B3P6D26 |
| 0.25% | FOLD | AMICUS THERAPEUTICS INC | -- | $196,236.72 | 13,656 | B19FQ48 |
| 0.24% | IMVT | IMMUNOVANT INC | -- | $189,372.78 | 7,758 | BJRFSB7 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $188,941.83 | 3,421 | BRJ3GY4 |
| 0.23% | TERN | TERNS PHARMACEUTICALS INC | -- | $185,428.72 | 3,986 | BMDJ0C9 |
| 0.23% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $180,645.15 | 4,515 | BFZQ0L8 |
| 0.22% | LGND | LIGAND PHARMACEUTICALS | -- | $176,531.70 | 870 | 2501578 |
| 0.22% | APGE | APOGEE THERAPEUTICS INC | -- | $174,501.30 | 2,427 | BM9HHL5 |
| 0.22% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $171,820.53 | 5,523 | BTZRLN8 |
| 0.22% | ERAS | ERASCA INC | -- | $170,999.10 | 12,555 | BNLYBF3 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $164,590.79 | 13,913 | BFNF1D6 |
| 0.20% | ADMA | ADMA BIOLOGICS INC | -- | $159,590.10 | 10,534 | B9NSBM2 |
| 0.20% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $158,938.75 | 2,957 | BQS9486 |
| 0.20% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $157,420.51 | 4,199 | BDD19F8 |
| 0.19% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $154,327.68 | 7,488 | 2713317 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $143,586.54 | 5,017 | BP8JSP4 |
| 0.17% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $138,629.15 | 4,685 | BKY5JZ8 |
| 0.17% | SYRE | SPYRE THERAPEUTICS INC | -- | $136,942.37 | 3,433 | BQBBDY8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $133,499.30 | 6,490 | BD2B4V0 |
| 0.16% | IDYA | IDEAYA BIOSCIENCES INC | -- | $128,389.20 | 3,880 | BK0VHF6 |
| 0.16% | TARS | TARSUS PHARMACEUTICALS INC | -- | $127,764.80 | 1,880 | BMH5RL1 |
| 0.16% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $126,621.67 | 2,537 | B72ZBG4 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $123,350.50 | 5,422 | BKX9VD3 |
| 0.15% | TWST | TWIST BIOSCIENCE CORP | -- | $117,115.68 | 2,706 | BGKG6G7 |
| 0.14% | DYN | DYNE THERAPEUTICS INC | -- | $113,290.24 | 6,322 | BN15WD1 |
| 0.14% | BEAM | BEAM THERAPEUTICS INC | -- | $112,968.40 | 4,490 | BK6L288 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $112,966.92 | 2,827 | BL55460 |
| 0.14% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $112,402.77 | 4,269 | BLB0YQ9 |
| 0.14% | VCYT | VERACYTE INC | -- | $112,358.61 | 3,497 | BFTWZY0 |
| 0.14% | TVTX | TRAVERE THERAPEUTICS INC | -- | $110,088.00 | 3,960 | BLFGJD5 |
| 0.13% | MAZE | MAZE THERAPEUTICS INC | -- | $106,897.09 | 2,129 | BSRK699 |
| 0.13% | ALMS | ALUMIS INC | -- | $106,757.43 | 4,303 | BPLQG36 |
| 0.13% | APLS | APELLIS PHARMACEUTICALS INC | -- | $105,988.24 | 5,596 | BYTQ6X1 |
| 0.13% | TNGX | TANGO THERAPEUTICS INC | -- | $103,125.30 | 5,961 | BP2P6L0 |
| 0.13% | IRON | DISC MEDICINE INC | -- | $100,386.88 | 1,672 | BMGJZJ8 |
| 0.12% | TXG | 10X GENOMICS INC-CLASS A | -- | $96,843.66 | 5,154 | BKS3RS7 |
| 0.12% | DAWN | DAY ONE BIOPHARMACEUTICALS I | -- | $96,811.33 | 4,543 | BLB0YH0 |
| 0.12% | WVE | WAVE LIFE SCIENCES LTD | -- | $96,374.04 | 7,402 | BYZG9R0 |
| 0.12% | MLYS | MINERALYS THERAPEUTICS INC | -- | $91,691.19 | 3,501 | BP9N0G0 |
| 0.12% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $91,514.22 | 1,999 | BRXB0C0 |
| 0.11% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $91,100.46 | 4,269 | BJ62Z18 |
| 0.11% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $90,381.00 | 3,846 | BN7Q7R7 |
| 0.11% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $88,963.35 | 6,755 | BJ5FZ74 |
| 0.11% | ORKA | ORUKA THERAPEUTICS INC | -- | $85,720.00 | 2,143 | BKVF0J2 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $85,551.64 | 2,362 | BMVNDH9 |
| 0.11% | STOK | STOKE THERAPEUTICS INC | -- | $83,871.13 | 2,527 | BJQ05Z6 |
| 0.10% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,598.04 | 9,429 | BNZB1X8 |
| 0.10% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $81,412.20 | 5,836 | BFWLC09 |
| 0.10% | RLAY | RELAY THERAPEUTICS INC | -- | $79,461.20 | 7,670 | BN2R582 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $79,327.44 | 1,224 | BDRW1L7 |
| 0.10% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $78,723.54 | 4,359 | BV2DHY6 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $77,825.52 | 22,756 | BM9FJ13 |
| 0.10% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $76,585.74 | 9,317 | 2100362 |
| 0.10% | SRPT | SAREPTA THERAPEUTICS INC | -- | $76,046.80 | 4,637 | B8DPDT7 |
| 0.10% | ZYME | ZYMEWORKS INC | -- | $75,778.56 | 3,312 | BPCQZY9 |
| 0.09% | GRAL | GRAIL INC | -- | $74,278.50 | 1,725 | BSLSSX7 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $73,669.68 | 1,974 | BQKXDX4 |
| 0.09% | NVAX | NOVAVAX INC | -- | $73,610.12 | 7,192 | BJDQXG4 |
| 0.09% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $72,951.79 | 2,627 | BMFD115 |
| 0.09% | INVA | INNOVIVA INC | -- | $72,897.27 | 3,309 | BDDXF67 |
| 0.09% | VCEL | VERICEL CORP | -- | $72,845.87 | 2,239 | BSBMN89 |
| 0.09% | PHVS | PHARVARIS NV | -- | $72,065.70 | 2,835 | BMZ2X38 |
| 0.09% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $71,880.85 | 2,581 | BCBVTX1 |
| 0.09% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $70,377.89 | 2,549 | BKSGZN7 |
| 0.09% | ANIP | ANI PHARMACEUTICALS INC | -- | $70,137.55 | 995 | BCDWBX6 |
| 0.09% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $69,862.50 | 3,726 | BMX9K07 |
| 0.09% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $69,569.28 | 17,568 | BF0DMK7 |
| 0.09% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $68,005.39 | 4,861 | BPCK358 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $67,650.32 | 2,588 | BBC9WC7 |
| 0.08% | NRIX | NURIX THERAPEUTICS INC | -- | $67,454.40 | 4,485 | BMVLGP2 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $65,407.76 | 5,126 | BYZM6C2 |
| 0.08% | TRVI | TREVI THERAPEUTICS INC | -- | $62,481.75 | 5,675 | BJH9ZN0 |
| 0.08% | ARDX | ARDELYX INC | -- | $62,146.56 | 10,752 | BN89V40 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $59,757.30 | 4,955 | BYSS4X4 |
| 0.08% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $59,590.66 | 1,931 | BLCD809 |
| 0.07% | ATAI | ATAIBECKLEY INC | -- | $59,313.06 | 16,074 | BWJDYK1 |
| 0.07% | RAPP | RAPPORT THERAPEUTICS INC | -- | $58,686.72 | 2,108 | BR3T9B6 |
| 0.07% | ZBIO | ZENAS BIOPHARMA INC | -- | $57,119.04 | 2,376 | BQB42H3 |
| 0.07% | VIR | VIR BIOTECHNOLOGY INC | -- | $57,013.82 | 6,157 | BK4PZ38 |
| 0.07% | HROW | HARROW INC | -- | $55,855.80 | 1,638 | BHNDW86 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $55,608.00 | 1,986 | BQXJKH2 |
| 0.07% | PGEN | PRECIGEN INC | -- | $54,966.60 | 15,660 | BKM5C84 |
| 0.07% | KOD | KODIAK SCIENCES INC | -- | $54,450.12 | 2,348 | BFXC933 |
| 0.07% | TSHA | TAYSHA GENE THERAPIES INC | -- | $54,432.27 | 12,123 | BNC1BX1 |
| 0.06% | ORIC | ORIC PHARMACEUTICALS INC | -- | $51,300.90 | 4,311 | BKVDFF7 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $51,220.22 | 3,482 | BMZ4LN0 |
| 0.06% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $50,632.60 | 3,305 | BYP80F1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $49,777.20 | 1,980 | BQNKXX2 |
| 0.06% | EYPT | EYEPOINT INC | -- | $48,351.60 | 3,663 | BMGS7L1 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $48,300.00 | 1,400 | BX7RSN3 |
| 0.06% | ALVO | ALVOTECH SA | -- | $48,073.38 | 13,854 | BPNTJ34 |
| 0.06% | SVRA | SAVARA INC | -- | $47,276.25 | 9,005 | BYXGN81 |
| 0.06% | BCAX | BICARA THERAPEUTICS INC | -- | $46,535.75 | 2,425 | BQB42F1 |
| 0.06% | ABCL | ABCELLERA BIOLOGICS INC | -- | $46,228.54 | 13,246 | BL53SR3 |
| 0.06% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $46,153.62 | 2,881 | BP7KZP7 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $44,869.29 | 907 | BL95N25 |
| 0.06% | GERN | GERON CORP | -- | $44,633.42 | 28,249 | 2370381 |
| 0.06% | INBX | INHIBRX BIOSCIENCES INC | -- | $44,337.30 | 645 | BNSP8K3 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $44,240.52 | 1,902 | B3X26D8 |
| 0.06% | AVBP | ARRIVENT BIOPHARMA INC | -- | $43,689.20 | 1,828 | BMGTLY5 |
| 0.05% | QURE | UNIQURE NV | -- | $42,816.21 | 2,757 | BJFSR88 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $42,166.19 | 5,399 | B8K7T65 |
| 0.05% | GHRS | GH RESEARCH PLC | -- | $41,022.80 | 2,744 | BP6C0S2 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $40,098.24 | 7,344 | BLR7H87 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $39,614.40 | 11,790 | BMFJJ97 |
| 0.05% | URGN | UROGEN PHARMA LTD | -- | $38,207.68 | 2,072 | BZ7PJQ1 |
| 0.05% | XNCR | XENCOR INC | -- | $37,920.00 | 3,160 | BGCYWN8 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $37,911.72 | 2,238 | BD06CS0 |
| 0.05% | MNKD | MANNKIND CORP | -- | $37,641.53 | 13,589 | BF081J4 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $36,996.30 | 2,035 | BNFWZS4 |
| 0.05% | SPRY | ARS PHARMACEUTICALS INC | -- | $36,706.25 | 4,375 | BMCR7V2 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $36,514.77 | 4,089 | BRXYZ57 |
| 0.05% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $36,261.12 | 8,512 | BZ0QMB7 |
| 0.05% | ANNX | ANNEXON INC | -- | $36,246.64 | 6,404 | BMVV9R5 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $36,163.54 | 2,663 | BMFX8Y7 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $35,262.86 | 2,614 | BM90J52 |
| 0.04% | OMER | OMEROS CORP | -- | $35,125.41 | 3,139 | B4NB858 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $35,095.32 | 7,499 | BYWVTY5 |
| 0.04% | ARVN | ARVINAS INC | -- | $34,615.56 | 2,842 | BDZ30Q0 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $33,302.50 | 3,850 | BYZD465 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $32,997.96 | 1,291 | BKLCWZ3 |
| 0.04% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $32,634.39 | 3,147 | BJLKVS6 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $31,835.21 | 1,733 | BD9GVY0 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $31,588.05 | 2,171 | BQS7491 |
| 0.04% | TBPH | THERAVANCE BIOPHARMA INC | -- | $30,922.32 | 2,244 | BMNDK09 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $29,708.64 | 1,587 | BT9K6D8 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $29,152.55 | 7,987 | BPBJFM7 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $27,580.68 | 828 | BPBPCG8 |
| 0.03% | CMPS | COMPASS PATHWAYS PLC | -- | $26,652.69 | 4,171 | BMC3HS7 |
| 0.03% | PSNL | PERSONALIS INC | -- | $26,409.60 | 3,930 | BJQ0608 |
| 0.03% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $26,315.79 | 3,561 | BFYQFJ2 |
| 0.03% | ESPR | ESPERION THERAPEUTICS INC | -- | $25,812.76 | 10,579 | BBNBTD2 |
| 0.03% | DSGN | DESIGN THERAPEUTICS INC | -- | $25,522.64 | 2,522 | BMFK3H6 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $25,204.88 | 3,448 | BQHN6C7 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $24,870.16 | 2,492 | BLFBZ32 |
| 0.03% | REPL | REPLIMUNE GROUP INC | -- | $24,790.08 | 3,472 | BDDVW37 |
| 0.03% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $24,264.00 | 7,200 | B3MZ6K5 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $23,868.00 | 9,945 | BFZNYB7 |
| 0.03% | VNDA | VANDA PHARMACEUTICALS INC | -- | $23,038.15 | 2,615 | B12W3P6 |
| 0.03% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $22,623.59 | 4,783 | BDFKQ07 |
| 0.03% | CRMD | CORMEDIX INC | -- | $22,497.60 | 3,488 | BJ0LT31 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $22,488.84 | 1,188 | BGL0JK3 |
| 0.03% | KMDA | KAMADA LTD | -- | $22,211.10 | 2,553 | B2Q9833 |
| 0.03% | NMRA | NEUMORA THERAPEUTICS INC | -- | $22,182.00 | 7,394 | BN4JN37 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $22,059.70 | 2,390 | BRCFFK6 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $21,947.43 | 2,383 | B91XRN2 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $21,703.98 | 5,399 | BYVQJ96 |
| 0.03% | LXEO | LEXEO THERAPEUTICS INC | -- | $21,505.14 | 3,229 | BQ6C357 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $21,484.17 | 1,693 | BP81RK8 |
| 0.03% | IVVD | INVIVYD INC | -- | $21,341.10 | 12,265 | BM8NHS1 |
| 0.03% | AVIR | ATEA PHARMACEUTICALS INC | -- | $21,087.70 | 3,457 | BLN9Z50 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $21,049.91 | 2,527 | BKLXFX5 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $20,811.90 | 802 | BQD3J33 |
| 0.03% | GLPG | GALAPAGOS NV-SPON ADR | -- | $20,326.11 | 641 | B292NQ7 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,911.25 | 937 | BTNMG41 |
| 0.02% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $19,764.36 | 6,417 | BMCWKZ2 |
| 0.02% | RGNX | REGENXBIO INC | -- | $19,205.37 | 2,241 | BZ0G875 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $18,386.10 | 3,954 | BYTYP72 |
| 0.02% | FULC | FULCRUM THERAPEUTICS INC | -- | $18,314.10 | 2,394 | BJDX8Z9 |
| 0.02% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $17,771.46 | 13,362 | B4N8MH9 |
| 0.02% | LRMR | LARIMAR THERAPEUTICS INC | -- | $17,405.86 | 3,788 | BMXNGZ6 |
| 0.02% | KYTX | KYVERNA THERAPEUTICS INC | -- | $17,354.05 | 1,939 | BSMLR16 |
| 0.02% | ACRS | ACLARIS THERAPEUTICS INC | -- | $16,977.84 | 4,796 | BYV2W40 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $16,827.75 | 1,385 | BQV0J03 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $16,685.46 | 2,809 | BP81R42 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $16,668.94 | 3,169 | 2107437 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,230.60 | 1,278 | B9L5200 |
| 0.02% | PEPG | PEPGEN INC | -- | $16,203.98 | 3,043 | BMTX3D7 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $16,163.00 | 4,618 | BFY7DC4 |
| 0.02% | ABSI | ABSCI CORP | -- | $15,907.84 | 6,656 | BN94K69 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,865.98 | 1,349 | BM7V485 |
| 0.02% | NGNE | NEUROGENE INC | -- | $14,734.35 | 685 | BS2F741 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $14,432.90 | 2,858 | BMVBZF5 |
| 0.02% | EOLS | EVOLUS INC | -- | $14,378.70 | 2,870 | BDRJH21 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,345.10 | 2,079 | BL5B6Z1 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $13,398.66 | 4,444 | BZC0D70 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $13,286.00 | 1,022 | BPRBTY7 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $13,157.00 | 2,230 | B7F2TY6 |
| 0.02% | CABA | CABALETTA BIO INC | -- | $13,032.54 | 4,259 | BK5MWR1 |
| 0.02% | NBP | NOVABRIDGE BIOSCIENCES | -- | $13,018.00 | 4,600 | BKRRKY7 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,784.32 | 8,878 | BFMLGR4 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,264.70 | 2,503 | BMF7DT9 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,666.08 | 4,289 | BKX9NQ0 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $11,614.19 | 2,607 | BY7RB53 |
| 0.01% | OABI | OMNIAB INC | -- | $11,404.09 | 6,371 | BN13S71 |
| 0.01% | CADL | CANDEL THERAPEUTICS INC | -- | $11,348.10 | 2,430 | BP0TQC5 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $10,843.32 | 1,658 | 2517058 |
| 0.01% | EDIT | EDITAS MEDICINE INC | -- | $10,545.68 | 4,322 | BZ8FPH3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $10,495.80 | 2,499 | BPRB2N7 |
| 0.01% | VOR | VOR BIOPHARMA INC | -- | $10,064.95 | 745 | BRJJYT3 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $9,779.88 | 2,046 | BKDQKM6 |
| 0.01% | HUMA | HUMACYTE INC | -- | $9,612.92 | 8,287 | BMYTJP4 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $8,720.50 | 5,350 | BRK0149 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $8,403.44 | 1,258 | BKC9SX3 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $8,218.79 | 8,655 | BNR5QT9 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,775.68 | 4,136 | BNYJR68 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $7,148.12 | 1,372 | BP2NYN2 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,660.72 | 3,364 | BPTK6Z2 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,609.51 | 2,369 | BP7L561 |
| 0.01% | CDXS | CODEXIS INC | -- | $6,435.17 | 3,997 | B5LL2C2 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,279.63 | 7,367 | BNNXX52 |
| 0.01% | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $5,699.76 | 4,318 | BNNXX18 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $5,348.76 | 2,523 | BKTV702 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,901.67 | 963 | BTXQTX3 |
| 0.01% | GOSS | GOSSAMER BIO INC | -- | $4,477.22 | 10,243 | BJ0CK86 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,242.70 | 2,755 | BLBR8D5 |
| -- | STRO | SUTRO BIOPHARMA INC | -- | $23.08 | 01 | BTFHQP5 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 32.21% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,576,818 | -- | 4,475 | -- |
| 30.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 24,525,168 | -- | 4,291 | -- |
| 25.27% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 20,067,085 | -- | 3,511 | -- |
| 18.99% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,083,178 | -- | 2,639 | -- |
| 17.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 14,197,277 | -- | 2,484 | -- |
| 4.56% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,617,905 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $23,425,202.59 | 23,425,203 | -- |
Index
as of 12/31/2025
- Total Number of Companies262
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$7.32 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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