BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,190,299
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/27/2026- NAV
- NAV Change
- Market Price $82.09
- Market Price Change $-0.62
- Trading Volume (M) 7,697
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $76,190,299
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/27/2026- NAV
- NAV Change
- Market Price $82.09
- Market Price Change $-0.62
- Trading Volume (M) 7,697
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2026. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/27/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.82% | AMGN | AMGEN INC | -- | $3,670,882.38 | 10,791 | 2023607 |
| 4.72% | GILD | GILEAD SCIENCES INC | -- | $3,592,457.75 | 28,121 | 2369174 |
| 4.71% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,590,838.29 | 8,429 | 2931034 |
| 4.13% | REGN | REGENERON PHARMACEUTICALS | -- | $3,146,747.88 | 4,227 | 2730190 |
| 2.18% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,664,719.96 | 5,396 | B00FWN1 |
| 1.57% | INSM | INSMED INC | -- | $1,192,952.54 | 8,773 | 2614487 |
| 1.42% | BIIB | BIOGEN INC | -- | $1,078,780.57 | 5,971 | 2455965 |
| 1.39% | RVMD | REVOLUTION MEDICINES INC | -- | $1,061,918.55 | 8,065 | BL71K91 |
| 1.33% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,010,943.17 | 1,783 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $905,219.70 | 1,155 | BDVLM39 |
| 1.14% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $865,697.40 | 17,436 | BMVP7Y0 |
| 1.06% | ROIV | ROIVANT SCIENCES LTD | -- | $811,381.90 | 29,134 | BMW4NZ9 |
| 1.05% | ILMN | ILLUMINA INC | -- | $799,908.48 | 6,224 | 2613990 |
| 1.03% | MRNA | MODERNA INC | -- | $782,755.10 | 16,073 | BGSXTS3 |
| 1.02% | INCY | INCYTE CORP | -- | $775,482.93 | 8,102 | 2471950 |
| 0.92% | SMMT | SUMMIT THERAPEUTICS INC | -- | $698,107.20 | 31,560 | BMTVQS7 |
| 0.91% | VTRS | VIATRIS INC | -- | $694,070.65 | 46,865 | BMWS3X9 |
| 0.77% | BBIO | BRIDGEBIO PHARMA INC | -- | $588,037.32 | 7,891 | BK1KWG8 |
| 0.75% | -- | ASCENDIS PHARMA A/S | -- | $567,783.30 | 2,505 | -- |
| 0.69% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $523,171.44 | 4,086 | 2623911 |
| 0.66% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $504,056.10 | 2,505 | B4Q5ZN4 |
| 0.64% | MEDP | MEDPACE HOLDINGS INC | -- | $486,682.35 | 1,155 | BDCBC61 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $485,764.06 | 934 | BD59BS7 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $485,746.75 | 6,725 | BDJ0LS6 |
| 0.62% | BNTX | BIONTECH SE-ADR | -- | $473,252.22 | 4,637 | BK6H543 |
| 0.62% | GH | GUARDANT HEALTH INC | -- | $472,324.50 | 5,337 | BFXC911 |
| 0.62% | EXEL | EXELIXIS INC | -- | $471,995.15 | 10,571 | 2576941 |
| 0.60% | SNY | SANOFI-ADR | -- | $457,164.00 | 9,960 | 2964557 |
| 0.55% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $421,185.54 | 7,828 | 2437071 |
| 0.55% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $419,667.20 | 5,702 | BYQBFJ8 |
| 0.51% | AXSM | AXSOME THERAPEUTICS INC | -- | $390,166.80 | 2,082 | BYZR4X4 |
| 0.51% | ONC | BEONE MEDICINES LTD-ADR | -- | $388,868.90 | 1,301 | BYYWPW6 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $375,342.66 | 1,134 | BQ721R4 |
| 0.49% | TEM | TEMPUS AI INC-CL A | -- | $372,447.60 | 7,070 | BSLSJJ0 |
| 0.46% | PCVX | VAXCYTE INC | -- | $349,780.04 | 5,857 | BKPVGH6 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $325,118.00 | 1,192 | BD6JX35 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $310,039.20 | 2,980 | BMVBZD3 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $309,809.96 | 4,804 | 2975098 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $308,862.40 | 5,014 | BBBSBJ5 |
| 0.40% | IBRX | IMMUNITYBIO INC | -- | $305,079.21 | 41,849 | BNSP0B8 |
| 0.38% | KYMR | KYMERA THERAPEUTICS INC | -- | $287,864.28 | 3,321 | BMPRZV5 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $279,638.10 | 2,499 | BLC89B2 |
| 0.34% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $255,928.98 | 2,598 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $241,885.84 | 6,608 | BLR6XK8 |
| 0.32% | ERAS | ERASCA INC | -- | $241,347.45 | 12,603 | BNLYBF3 |
| 0.31% | IMVT | IMMUNOVANT INC | -- | $237,173.94 | 8,287 | BJRFSB7 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $236,856.00 | 2,780 | BF2YWG4 |
| 0.31% | PTCT | PTC THERAPEUTICS INC | -- | $233,132.96 | 3,368 | B17VCN9 |
| 0.30% | SYRE | SPYRE THERAPEUTICS INC | -- | $229,792.40 | 3,196 | BQBBDY8 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $229,660.34 | 3,437 | BRBCSP4 |
| 0.30% | TERN | TERNS PHARMACEUTICALS INC | -- | $229,220.55 | 4,329 | BMDJ0C9 |
| 0.30% | CAI | CARIS LIFE SCIENCES INC | -- | $228,915.98 | 11,486 | BT18HP9 |
| 0.30% | ALKS | ALKERMES PLC | -- | $228,824.32 | 6,784 | B3P6D26 |
| 0.30% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $227,130.88 | 2,456 | BJDX8Y8 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,062.85 | 5,203 | BYTQ6X1 |
| 0.26% | CRSP | CRISPR THERAPEUTICS AG | -- | $199,217.93 | 3,907 | BDHF4K6 |
| 0.26% | LGND | LIGAND PHARMACEUTICALS | -- | $195,849.90 | 810 | 2501578 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $192,914.57 | 2,231 | BM9HHL5 |
| 0.25% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,374.19 | 4,869 | BLB0YQ9 |
| 0.25% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $192,288.66 | 4,154 | BFZQ0L8 |
| 0.24% | XENE | XENON PHARMACEUTICALS INC | -- | $183,724.36 | 3,386 | BRJ3GY4 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $174,569.28 | 5,088 | BTZRLN8 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $164,598.44 | 4,262 | BDD19F8 |
| 0.21% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $160,971.42 | 12,806 | BFNF1D6 |
| 0.20% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $154,695.10 | 6,937 | 2713317 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $153,241.55 | 3,755 | BLFGJD5 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $152,256.00 | 2,496 | BGKG6G7 |
| 0.20% | ORKA | ORUKA THERAPEUTICS INC | -- | $150,488.30 | 1,970 | BKVF0J2 |
| 0.19% | TNGX | TANGO THERAPEUTICS INC | -- | $144,341.06 | 5,482 | BP2P6L0 |
| 0.19% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $143,832.09 | 3,173 | BQS9486 |
| 0.19% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $142,445.10 | 4,678 | BP8JSP4 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $133,774.24 | 4,366 | BKY5JZ8 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $128,692.76 | 6,454 | BD2B4V0 |
| 0.17% | ALMS | ALUMIS INC | -- | $127,363.50 | 5,146 | BPLQG36 |
| 0.16% | BEAM | BEAM THERAPEUTICS INC | -- | $120,947.26 | 4,147 | BK6L288 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $120,868.00 | 6,700 | BN15WD1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $118,130.48 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $115,439.64 | 2,334 | B72ZBG4 |
| 0.14% | VCYT | VERACYTE INC | -- | $109,572.45 | 3,237 | BFTWZY0 |
| 0.14% | KOD | KODIAK SCIENCES INC | -- | $109,569.24 | 2,484 | BFXC933 |
| 0.14% | RLAY | RELAY THERAPEUTICS INC | -- | $108,761.25 | 7,275 | BN2R582 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $108,523.30 | 2,417 | BMFD115 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $108,261.12 | 2,904 | BL55460 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $106,992.90 | 1,554 | BMGJZJ8 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $106,676.64 | 4,788 | BKS3RS7 |
| 0.14% | ADMA | ADMA BIOLOGICS INC | -- | $105,966.35 | 9,695 | B9NSBM2 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $105,530.76 | 1,732 | BMH5RL1 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $105,391.00 | 3,575 | BK0VHF6 |
| 0.12% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $94,352.67 | 3,933 | BJ62Z18 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,869.00 | 10,210 | 2100362 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $89,500.68 | 4,266 | B8DPDT7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $89,054.07 | 6,267 | BJ5FZ74 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $88,594.44 | 5,412 | BFWLC09 |
| 0.11% | GRAL | GRAIL INC | -- | $87,151.68 | 1,584 | BSLSSX7 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $87,050.88 | 3,048 | BPCQZY9 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $86,961.78 | 3,222 | BP9N0G0 |
| 0.11% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $85,136.84 | 4,058 | BV2DHY6 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $84,356.72 | 8,861 | BNZB1X8 |
| 0.11% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $81,550.70 | 1,870 | BRXB0C0 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $81,237.75 | 3,435 | BMX9K07 |
| 0.11% | TYRA | TYRA BIOSCIENCES INC | -- | $80,190.24 | 2,172 | BMVNDH9 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $78,342.04 | 2,324 | BJQ05Z6 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $77,686.95 | 591 | BNSP8K3 |
| 0.10% | VCEL | VERICEL CORP | -- | $76,313.64 | 2,067 | BSBMN89 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $75,487.36 | 4,472 | BPCK358 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $75,411.00 | 3,591 | BN7Q7R7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $75,180.11 | 1,129 | BDRW1L7 |
| 0.10% | PHVS | PHARVARIS NV | -- | $74,875.68 | 2,608 | BMZ2X38 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $74,460.86 | 5,218 | BJH9ZN0 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $73,936.08 | 21,246 | BM9FJ13 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,122.75 | 2,355 | BKSGZN7 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $72,674.80 | 913 | BCDWBX6 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $72,016.08 | 11,148 | BNC1BX1 |
| 0.09% | SION | SIONNA THERAPEUTICS INC | -- | $71,283.78 | 1,818 | BQKXDX4 |
| 0.09% | INVA | INNOVIVA INC | -- | $70,407.04 | 3,014 | BDDXF67 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $69,823.44 | 2,621 | BBC9WC7 |
| 0.09% | NRIX | NURIX THERAPEUTICS INC | -- | $69,027.14 | 4,186 | BMVLGP2 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $68,711.40 | 1,941 | BR3T9B6 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $68,053.44 | 6,396 | BK4PZ38 |
| 0.08% | ATAI | ATAIBECKLEY INC | -- | $64,158.22 | 14,783 | BWJDYK1 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $62,696.32 | 4,808 | BYZM6C2 |
| 0.08% | HROW | HARROW INC | -- | $62,570.51 | 1,511 | BHNDW86 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,895.45 | 3,105 | BP7KZP7 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,786.19 | 9,981 | BN89V40 |
| 0.08% | MBX | MBX BIOSCIENCES INC | -- | $58,377.22 | 1,826 | BQXJKH2 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $58,241.12 | 2,384 | BCBVTX1 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $57,963.03 | 2,579 | BQB42F1 |
| 0.08% | NVCR | NOVOCURE LTD | -- | $57,807.36 | 4,632 | BYSS4X4 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $57,514.24 | 16,768 | BF0DMK7 |
| 0.07% | PGEN | PRECIGEN INC | -- | $57,039.84 | 14,404 | BKM5C84 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $53,523.04 | 3,362 | BYP80F1 |
| 0.07% | NVAX | NOVAVAX INC | -- | $53,496.03 | 6,629 | BJDQXG4 |
| 0.07% | WVE | WAVE LIFE SCIENCES LTD | -- | $53,181.22 | 7,663 | BYZG9R0 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $51,828.26 | 1,958 | BSRK699 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,334.40 | 12,340 | BL53SR3 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $51,015.06 | 1,682 | BMGTLY5 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $50,951.04 | 1,784 | BLCD809 |
| 0.07% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $49,860.69 | 3,261 | BMZ4LN0 |
| 0.06% | GHRS | GH RESEARCH PLC | -- | $49,496.97 | 2,526 | BP6C0S2 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $47,101.46 | 839 | BL95N25 |
| 0.06% | EYPT | EYEPOINT INC | -- | $45,818.40 | 3,369 | BMGS7L1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $45,688.89 | 1,821 | BQNKXX2 |
| 0.06% | QURE | UNIQURE NV | -- | $45,394.40 | 2,536 | BJFSR88 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $45,258.08 | 1,904 | BZ7PJQ1 |
| 0.06% | ALVO | ALVOTECH SA | -- | $44,368.50 | 13,445 | BPNTJ34 |
| 0.06% | SVRA | SAVARA INC | -- | $42,750.60 | 8,285 | BYXGN81 |
| 0.06% | OMER | OMEROS CORP | -- | $42,510.16 | 2,884 | B4NB858 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,351.76 | 1,292 | BX7RSN3 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $42,029.75 | 1,645 | B3X26D8 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $41,636.34 | 4,086 | BKVDFF7 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,334.48 | 6,754 | BLR7H87 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $41,251.21 | 2,219 | BQB42H3 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,349.19 | 4,963 | B8K7T65 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,333.00 | 3,805 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $39,965.90 | 1,846 | BNFWZS4 |
| 0.05% | GERN | GERON CORP | -- | $39,757.05 | 25,985 | 2370381 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,431.28 | 2,058 | BD06CS0 |
| 0.05% | XNCR | XENCOR INC | -- | $39,129.70 | 2,987 | BGCYWN8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $37,724.71 | 2,477 | BMFX8Y7 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $37,157.54 | 3,206 | BJLKVS6 |
| 0.05% | ANNX | ANNEXON INC | -- | $35,935.10 | 5,891 | BMVV9R5 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $35,348.18 | 10,843 | BMFJJ97 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,695.84 | 2,064 | BMNDK09 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $34,137.60 | 3,840 | BMC3HS7 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $33,503.84 | 7,828 | BZ0QMB7 |
| 0.04% | MNKD | MANNKIND CORP | -- | $32,985.46 | 12,542 | BF081J4 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $32,637.57 | 2,129 | BQS7491 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $32,125.94 | 3,542 | BYZD465 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,998.75 | 4,025 | BMCR7V2 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $31,912.02 | 1,767 | BT9K6D8 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $31,879.50 | 2,406 | BM90J52 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $30,522.60 | 1,395 | BD9GVY0 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $30,225.80 | 1,210 | BKLCWZ3 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,909.88 | 3,276 | BFYQFJ2 |
| 0.04% | ABSI | ABSCI CORP | -- | $29,686.85 | 6,121 | BN94K69 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $29,680.77 | 2,317 | BMFK3H6 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $29,583.84 | 6,896 | BYWVTY5 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $26,963.49 | 7,347 | BPBJFM7 |
| 0.04% | ARVN | ARVINAS INC | -- | $26,795.16 | 2,604 | BDZ30Q0 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $26,756.92 | 6,623 | B3MZ6K5 |
| 0.03% | ETON | ETON PHARMACEUTICALS INC | -- | $25,583.95 | 1,091 | BGL0JK3 |
| 0.03% | PSNL | PERSONALIS INC | -- | $25,383.64 | 4,259 | BJQ0608 |
| 0.03% | CRMD | CORMEDIX INC | -- | $25,070.92 | 3,206 | BJ0LT31 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $23,905.16 | 1,693 | BRJJYT3 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,805.00 | 3,174 | BQHN6C7 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $23,619.31 | 2,189 | B91XRN2 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,607.91 | 741 | BQD3J33 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,464.90 | 2,290 | BLFBZ32 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $21,993.75 | 765 | BPBPCG8 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,925.44 | 5,958 | BMCWKZ2 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $21,639.87 | 4,907 | BYV2W40 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $20,921.20 | 2,710 | BJDX8Z9 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,901.75 | 2,325 | BSMLR16 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,583.00 | 9,148 | BFZNYB7 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $20,434.90 | 1,129 | BS2CR64 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,428.71 | 2,199 | BRCFFK6 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,352.40 | 4,964 | BYVQJ96 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,217.60 | 1,560 | BP81RK8 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $19,620.36 | 4,419 | BMXNGZ6 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,608.75 | 2,075 | BKLXFX5 |
| 0.03% | LYEL | LYELL IMMUNOPHARMA INC | -- | $19,566.30 | 865 | BTNMG41 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,544.28 | 12,292 | B4N8MH9 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,253.60 | 2,348 | B2Q9833 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $18,719.04 | 2,976 | BP0TQC5 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,582.39 | 9,729 | BBNBTD2 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,984.64 | 2,584 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $17,765.82 | 2,061 | BZ0G875 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,195.88 | 604 | B292NQ7 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,034.08 | 3,178 | BLN9Z50 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,014.45 | 629 | BS2F741 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $16,711.88 | 2,971 | BQ6C357 |
| 0.02% | IVVD | INVIVYD INC | -- | $16,465.88 | 11,278 | BM8NHS1 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,411.43 | 2,417 | B12W3P6 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $16,069.83 | 1,239 | BPRBTY7 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $15,696.96 | 1,182 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,538.19 | 2,069 | B7F2TY6 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,425.80 | 4,420 | BDFKQ07 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,102.66 | 6,803 | BN4JN37 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $15,027.84 | 2,609 | BMVBZF5 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,944.02 | 1,911 | BL5B6Z1 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $14,268.80 | 5,096 | BFY7DC4 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,770.36 | 2,638 | BDRJH21 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $13,652.40 | 1,240 | BM7V485 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,296.96 | 2,916 | 2107437 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $12,424.48 | 1,273 | BQV0J03 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,416.46 | 3,774 | BYTYP72 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,415.43 | 2,383 | BMF7DT9 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $11,635.48 | 4,097 | BZC0D70 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $11,595.72 | 8,166 | BFMLGR4 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $11,484.86 | 3,974 | BZ8FPH3 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $11,395.56 | 3,916 | BK5MWR1 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $11,240.76 | 3,972 | BKX9NQ0 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $11,194.56 | 6,084 | BRK0149 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $11,102.67 | 4,569 | BKRRKY7 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $10,255.56 | 1,263 | BP2NYN2 |
| 0.01% | CDXS | CODEXIS INC | -- | $9,741.40 | 3,676 | B5LL2C2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $9,603.10 | 1,157 | BKC9SX3 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $9,421.80 | 2,298 | BPRB2N7 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,024.00 | 2,400 | BY7RB53 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $9,010.16 | 3,362 | BDDVW37 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,986.68 | 1,884 | BKDQKM6 |
| 0.01% | OABI | OMNIAB INC | -- | $8,435.52 | 5,858 | BN13S71 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $8,100.39 | 3,803 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,736.84 | 1,523 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,160.99 | 7,954 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $6,842.06 | 2,179 | BP7L561 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,768.56 | 2,318 | BKTV702 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,493.00 | 3,020 | BPTK6Z2 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,331.96 | 7,857 | BMYTJP4 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,176.10 | 8,823 | BNNXX52 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,890.72 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,480.00 | 2,800 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,461.60 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,533.79 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,282.52 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 35.99% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 27,419,870 | -- | 4,669 | -- |
| 28.53% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,740,921 | -- | 3,702 | -- |
| 27.16% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,695,571 | -- | 3,524 | -- |
| 20.34% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,498,187 | -- | 2,639 | -- |
| 16.97% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,925,923 | -- | 2,201 | -- |
| 4.88% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,717,451 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $25,640,826.29 | 25,640,826 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
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